lactic acid has been researched along with Leukemia in 21 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pharmacokinetic study was performed in 13 adult patients with acute nonlymphoblastic leukemia to compare two formulations of 4'-(9-acridinylamino)-methanesulphone-m-ansidide (AMSA): the original formulation, AMSA-NCL, and a water-soluble lyophilized formulation, AMSA-lactate (Bristol Myers, Syracuse, N." | 1.27 | Comparison of the pharmacokinetics of AMSA and AMSA-lactate in patients with acute nonlymphoblastic leukemia. ( Farmen, RH; Franks, CR; Liliemark, JO; Paul, CY; Peterson, CO; Uytdenhoef, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (38.10) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Mc Dermott, S | 1 |
| Dargan, C | 1 |
| Gonzalez Dominguez, E | 1 |
| Music Aplenc, L | 1 |
| Flatt, T | 1 |
| Iqbal, N | 1 |
| Leung, MHM | 1 |
| Shen, AQ | 1 |
| Scotland, S | 1 |
| Saland, E | 1 |
| Skuli, N | 1 |
| de Toni, F | 1 |
| Boutzen, H | 1 |
| Micklow, E | 1 |
| Sénégas, I | 1 |
| Peyraud, R | 1 |
| Peyriga, L | 1 |
| Théodoro, F | 1 |
| Dumon, E | 1 |
| Martineau, Y | 1 |
| Danet-Desnoyers, G | 1 |
| Bono, F | 1 |
| Rocher, C | 1 |
| Levade, T | 1 |
| Manenti, S | 1 |
| Junot, C | 1 |
| Portais, JC | 1 |
| Alet, N | 1 |
| Récher, C | 1 |
| Selak, MA | 1 |
| Carroll, M | 1 |
| Sarry, JE | 1 |
| Gottfried, E | 1 |
| Lang, SA | 1 |
| Renner, K | 1 |
| Bosserhoff, A | 1 |
| Gronwald, W | 1 |
| Rehli, M | 1 |
| Einhell, S | 1 |
| Gedig, I | 1 |
| Singer, K | 1 |
| Seilbeck, A | 1 |
| Mackensen, A | 1 |
| Grauer, O | 1 |
| Hau, P | 1 |
| Dettmer, K | 1 |
| Andreesen, R | 1 |
| Oefner, PJ | 1 |
| Kreutz, M | 1 |
| Zhang, L | 1 |
| Zhao, S | 1 |
| Duan, J | 1 |
| Hu, Y | 1 |
| Gu, N | 1 |
| Xu, H | 1 |
| Yang, XD | 1 |
| Goto, M | 2 |
| Miwa, H | 2 |
| Suganuma, K | 2 |
| Tsunekawa-Imai, N | 1 |
| Shikami, M | 2 |
| Mizutani, M | 1 |
| Mizuno, S | 2 |
| Hanamura, I | 2 |
| Nitta, M | 2 |
| Klawitter, J | 2 |
| Anderson, N | 1 |
| Christians, U | 1 |
| Leibfritz, D | 1 |
| Eckhardt, SG | 1 |
| Serkova, NJ | 1 |
| Imai, N | 1 |
| Gotou, M | 1 |
| Takahashi, M | 1 |
| Yamamoto, H | 1 |
| Hiramatsu, A | 1 |
| Wakabayashi, M | 1 |
| Watarai, M | 1 |
| Imamura, A | 1 |
| Mihara, H | 1 |
| Yadav, KS | 1 |
| Jacob, S | 1 |
| Sachdeva, G | 1 |
| Chuttani, K | 1 |
| Mishra, AK | 1 |
| Sawant, KK | 1 |
| MCKINNEY, GR | 1 |
| RUNDLES, RW | 1 |
| REMY, D | 1 |
| WIEDING, J | 1 |
| SINGER, Z | 1 |
| MASNY, N | 1 |
| KARDASZEWICZ, E | 1 |
| SANTAGATI, U | 1 |
| BOLDRINI, R | 1 |
| Kompanje, EJ | 1 |
| Jansen, TC | 1 |
| van der Hoven, B | 1 |
| Bakker, J | 1 |
| Natali, PG | 1 |
| Salsano, F | 1 |
| Viora, M | 1 |
| Nista, A | 1 |
| Malorni, W | 1 |
| Marolla, A | 1 |
| De Martino, C | 1 |
| Denis-Gay, M | 1 |
| Petit, JM | 1 |
| Mazat, JP | 1 |
| Ratinaud, MH | 1 |
| Michaelis, M | 1 |
| Matousek, J | 1 |
| Vogel, JU | 1 |
| Slavik, T | 1 |
| Langer, K | 1 |
| Cinatl, J | 2 |
| Kreuter, J | 1 |
| Schwabe, D | 1 |
| Schumpp, B | 1 |
| Schlaeger, EJ | 1 |
| White, MV | 1 |
| Kaplan, AP | 1 |
| Haak-Frendscho, M | 1 |
| Kaliner, M | 1 |
| Paul, CY | 1 |
| Liliemark, JO | 1 |
| Farmen, RH | 1 |
| Franks, CR | 1 |
| Uytdenhoef, M | 1 |
| Peterson, CO | 1 |
| Emmerich, B | 1 |
| Zubrod, E | 1 |
| Weber, H | 1 |
| Maubach, PA | 1 |
| Kersten, H | 1 |
| Kersten, W | 1 |
21 other studies available for lactic acid and Leukemia
| Article | Year |
|---|---|
Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single-institutional experience.
Topics: Adult; Blood Component Removal; Child; Critical Illness; Humans; Lactic Acid; Leukemia; Multiple Org | 2022 |
Microfluidic Assisted Nanoprecipitation of PLGA Nanoparticles for Curcumin Delivery to Leukemia Jurkat Cells.
Topics: Animals; Curcumin; Drug Delivery Systems; Humans; Jurkat Cells; Lactic Acid; Leukemia; Mice; Microfl | 2018 |
Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Blotting, Western; Cell P | 2013 |
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carcinoma; Cell Line, Tumor; | 2013 |
Enhancement of DC-mediated anti-leukemic immunity in vitro by WT1 antigen and CpG co-encapsulated in PLGA microparticles.
Topics: Animals; Antigens, Neoplasm; Cancer Vaccines; Cell Line, Tumor; CpG Islands; Cytotoxicity, Immunolog | 2013 |
Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress.
Topics: Adaptation, Physiological; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Dose-Respo | 2014 |
Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamide | 2009 |
Energy metabolism of leukemia cells: glycolysis versus oxidative phosphorylation.
Topics: Antimetabolites; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Drug Resistance, Neoplasm; Ener | 2010 |
Long circulating PEGylated PLGA nanoparticles of cytarabine for targeting leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Delayed-Action Preparations; | 2011 |
Lactate formation and glyoxalase activity in normal and leukemic human leukocytes in vitro.
Topics: Humans; Hydro-Lyases; In Vitro Techniques; Lactic Acid; Leukemia; Leukocytes | 1956 |
[Characteristics of leukemic blood cells. IV. Lactic acid dehydrogenase in leukemias].
Topics: Blood Cells; L-Lactate Dehydrogenase; Lactic Acid; Leukemia; Oxidoreductases | 1957 |
[Activity of lactic acid dehydrogenase in sera of patients with leukemia and other hematological diseases].
Topics: Hematologic Diseases; L-Lactate Dehydrogenase; Lactic Acid; Leukemia; Oxidation-Reduction; Oxidoredu | 1962 |
[Behavior of sugar, pyruvic acid and lactic acid in blood in lymphadenosis and chronic myeloid leukemia].
Topics: Blood Glucose; Humans; Lactic Acid; Leukemia; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BC | 1955 |
The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814-1869) in January 1843.
Topics: Germany; History, 19th Century; Humans; Lactic Acid; Leukemia; Male; Shock, Hemorrhagic | 2007 |
Inhibition of aerobic glycolysis in normal and neoplastic lymphoid cells induced by Lonidamine [1-(2,4-dichlorobenzyl)-I-H-indazol-3-carboxylic acid].
Topics: Aerobiosis; B-Lymphocytes; Dose-Response Relationship, Drug; Glycolysis; Humans; In Vitro Techniques | 1984 |
Modifications of oxido-reductase activities in adriamycin-resistant leukaemia K562 cells.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Drug Resistance, Neoplasm; Electron Transport Complex IV; | 1998 |
Bovine seminal ribonuclease attached to nanoparticles made of polylactic acid kills leukemia and lymphoma cell lines in vitro.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Division; Dose-Response Relationship, Drug; | 2000 |
Growth study of lactate and ammonia double-resistant clones of HL-60 cells.
Topics: Ammonium Chloride; Cell Division; Clone Cells; Drug Resistance; Glucose; Glutamine; Humans; Kinetics | 1992 |
Neutrophils and mast cells. Comparison of neutrophil-derived histamine-releasing activity with other histamine-releasing factors.
Topics: Animals; Basophils; Biomarkers, Tumor; Blood Platelets; Cell Line; Drug Stability; Histamine Release | 1988 |
Comparison of the pharmacokinetics of AMSA and AMSA-lactate in patients with acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Female; Humans; Lactates; Lactic Acid; Leukemia; | 1987 |
Relationship of queuine-lacking transfer RNA to the grade of malignancy in human leukemias and lymphomas.
Topics: Adolescent; Adult; Aged; Cell Differentiation; Child; Female; Guanine; Humans; Lactates; Lactic Acid | 1985 |