Page last updated: 2024-10-17

lactic acid and Left Ventricular Hypertrophy

lactic acid has been researched along with Left Ventricular Hypertrophy in 18 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Moxonidine is a new centrally active imidazoline-receptor agonist being effectively applied in the treatment of arterial hypertension due to its sympathicolytic potency."7.71[Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation]. ( Hamel, M; Hamm, C; Miric, M; Mitrovic, V; Thormann, J, 2001)
"Forty-one patients operated on for isolated aortic valve stenosis were randomly assigned to continuous coronary infusion with either potassium or esmolol during cardiopulmonary bypass."5.10Efficacy of esmolol as a myocardial protective agent during continuous retrograde blood cardioplegia. ( Al Attar, N; Callebert, J; Lessana, A; Maillet, JM; Mebazaa, A; Medini, B; Nataf, P; Payen, D; Raffoul, R; Ramadan, R; Ruffenach, A; Scorsin, M; Simoneau, F, 2003)
"Moxonidine is a new centrally active imidazoline-receptor agonist being effectively applied in the treatment of arterial hypertension due to its sympathicolytic potency."3.71[Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation]. ( Hamel, M; Hamm, C; Miric, M; Mitrovic, V; Thormann, J, 2001)
"As evidence on the predominant type of cardiac hypertrophy due to endurance running training is inconsistent, the aim of this study was to investigate the effect of increased training volume on echocardiographic variables of distance runners."2.72Concentric myocardial hypertrophy after one year of increased training volume in experienced distance runners. ( Raugaliene, R; Stasiulis, A; Venckunas, T, 2006)
"Development of heart failure is known to be associated with changes in energy substrate metabolism."1.39Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. ( Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P, 2013)
"Exercise-induced cardiac hypertrophy has been recently identified to be regulated in a sex-specific manner."1.37Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability. ( Benz, V; Böhm, C; Dragun, D; Foryst-Ludwig, A; Gürgen, D; Kintscher, U; Kreissl, MC; Mai, K; Regitz-Zagrosek, V; Schubert, C; Sprang, C; Spranger, J; Stawowy, P; Thalke, B; Unger, T, 2011)
"and results Left ventricular hypertrophy was induced surgically in Sprague-Dawley rats by inter-renal aortic constriction."1.35Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy. ( Akki, A; Seymour, AM, 2009)
"Captopril (23."1.29Captopril cardioplegia on myocardial protection in the hypertrophied rat hearts. ( Xu, SC; Zhang, YH, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (27.78)18.2507
2000's9 (50.00)29.6817
2010's2 (11.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Hiraki, N1
Tanaka, TD1
Yoshimura, M1
Schnelle, M1
Chong, M1
Zoccarato, A1
Elkenani, M1
Sawyer, GJ1
Hasenfuss, G1
Ludwig, C1
Shah, AM1
Akki, A1
Seymour, AM1
Foryst-Ludwig, A1
Kreissl, MC1
Sprang, C1
Thalke, B1
Böhm, C1
Benz, V1
Gürgen, D1
Dragun, D1
Schubert, C1
Mai, K1
Stawowy, P1
Spranger, J1
Regitz-Zagrosek, V1
Unger, T1
Kintscher, U1
Zhabyeyev, P1
Gandhi, M1
Mori, J1
Basu, R1
Kassiri, Z1
Clanachan, A1
Lopaschuk, GD2
Oudit, GY1
Scorsin, M1
Mebazaa, A1
Al Attar, N1
Medini, B1
Callebert, J1
Raffoul, R1
Ramadan, R1
Maillet, JM1
Ruffenach, A1
Simoneau, F1
Nataf, P1
Payen, D1
Lessana, A1
Minakawa, M1
Takeuchi, K2
Ito, K1
Tsushima, T1
Fukui, K1
Takaya, S1
Fukuda, I1
Venckunas, T1
Stasiulis, A1
Raugaliene, R1
Podesser, BK1
Jain, M1
Ngoy, S1
Apstein, CS1
Eberli, FR1
Barillas, R1
Friehs, I1
Cao-Danh, H2
Martinez, JF1
del Nido, PJ2
Buenaventura, P1
Glynn, P1
Simplaceanu, E1
McGowan, FX1
Zhang, YH1
Xu, SC1
Raizada, V1
Pathak, D1
Avery, G1
Woodfin, B1
Ishibashi, Y1
Shimada, T1
Nosaka, S1
Sano, K1
Oyake, N1
Kobayashi, S1
Umeno, T1
Yoshitomi, H1
Morioka, S1
Yuan, F1
Brandt, NR1
Pinto, JM1
Wasserlauf, BJ1
Myerburg, RJ1
Bassett, AL1
Mitrovic, V1
Hamel, M1
Miric, M1
Thormann, J1
Hamm, C1
Mohri, M1
Ichiki, T1
Hirooka, Y1
Takeshita, A1
Leong, HS1
Grist, M1
Parsons, H1
Wambolt, RB1
Brownsey, R1
Allard, MF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Outcome of Esmolol Potassium Cardioplegia Compared to Potassium Cardioplegia in Patients With Solitary Valvular Disease; Randomized Controlled Study[NCT04306913]80 participants (Anticipated)Interventional2020-04-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for lactic acid and Left Ventricular Hypertrophy

ArticleYear
Efficacy of esmolol as a myocardial protective agent during continuous retrograde blood cardioplegia.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aortic Valve Stenosis; Cardioplegic Solutions; Cardiopulmonary By

2003
Concentric myocardial hypertrophy after one year of increased training volume in experienced distance runners.
    British journal of sports medicine, 2006, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Cardiomegaly; Exercise Test; Humans; Hypertrophy, Left Ventricular; Lactic Acid;

2006

Other Studies

16 other studies available for lactic acid and Left Ventricular Hypertrophy

ArticleYear
A Man With Left Ventricular Hypertrophy.
    JAMA cardiology, 2022, 02-01, Volume: 7, Issue:2

    Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc

2022
In vivo [U-
    American journal of physiology. Heart and circulatory physiology, 2020, 08-01, Volume: 319, Issue:2

    Topics: Animals; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Energy Metabolis

2020
Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy.
    Cardiovascular research, 2009, Feb-15, Volume: 81, Issue:3

    Topics: Acyl-CoA Dehydrogenase; Animals; CD36 Antigens; Diabetes Mellitus, Type 2; Dietary Fats; Disease Mod

2009
Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:1

    Topics: Adipose Tissue; Animals; Blotting, Western; Calorimetry; Cardiomegaly; Echocardiography; Energy Meta

2011
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
    Cardiovascular research, 2013, Mar-15, Volume: 97, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hy

2013
Restoration of sarcoplasmic reticulum protein level by thyroid hormone contributes to partial improvement of myocardial function, but not to glucose metabolism in an early failing heart.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 24, Issue:4

    Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Disease Models, Animal; Disease Progression;

2003
Unveiling gender differences in demand ischemia: a study in a rat model of genetic hypertension.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2007, Volume: 31, Issue:2

    Topics: Animals; Coronary Circulation; Diastole; Disease Models, Animal; Disease Susceptibility; Female; Hyp

2007
Inhibition of glycogen synthase kinase-3beta improves tolerance to ischemia in hypertrophied hearts.
    The Annals of thoracic surgery, 2007, Volume: 84, Issue:1

    Topics: Animals; Body Weight; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycolysis; Hyper

2007
Improved protection of the hypertrophied left ventricle by histidine-containing cardioplegia.
    Circulation, 1995, Nov-01, Volume: 92, Issue:9 Suppl

    Topics: Animals; Cardiomegaly; Energy Metabolism; Heart; Heart Arrest, Induced; Histidine; Hydrogen-Ion Conc

1995
Captopril cardioplegia on myocardial protection in the hypertrophied rat hearts.
    International journal of cardiology, 1994, Volume: 47, Issue:2

    Topics: Animals; Captopril; Coronary Circulation; Creatine Kinase; Heart Arrest, Induced; Hypertrophy, Left

1994
Accelerated glycolysis in early hypertensive left ventricular hypertrophy.
    Cardiology, 1993, Volume: 83, Issue:3

    Topics: Animals; Blood Pressure; Energy Metabolism; Glycogen; Glycolysis; Hypertrophy, Left Ventricular; Lac

1993
Effects of heart rate on coronary circulation and external mechanical efficiency in elderly hypertensive patients with left ventricular hypertrophy.
    Clinical cardiology, 1996, Volume: 19, Issue:8

    Topics: Aged; Analysis of Variance; Coronary Circulation; Heart Failure; Heart Rate; Hemodynamics; Humans; H

1996
Hypertrophy decreases cardiac KATP channel responsiveness to exogenous and locally generated (glycolytic) ATP.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:10

    Topics: Adenosine Triphosphate; Animals; Cats; Cell Membrane Permeability; Female; Glycolysis; Hypertrophy,

1997
[Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:12

    Topics: Aged; Angina Pectoris; Antihypertensive Agents; Blood Flow Velocity; Coronary Circulation; Electroca

2001
Endogenous nitric oxide prevents myocardial ischemia in patients with hypertension and left ventricular hypertrophy.
    American heart journal, 2002, Volume: 143, Issue:4

    Topics: Aged; Cardiac Catheterization; Coronary Circulation; Enzyme Inhibitors; Female; Humans; Hypertension

2002
Accelerated rates of glycolysis in the hypertrophied heart: are they a methodological artifact?
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:5

    Topics: Animals; Artifacts; Blood Pressure; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; Heart Rate;

2002