lactic acid has been researched along with Kidney Diseases in 34 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The primary outcomes were mortality, occurrence of lactic acidosis and myocardial infarction (MI) in patients taking metformin during dialysis treatment for ≥12 months (long term)." | 5.01 | Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis. ( Abdel Shaheed, C; Carland, JE; Chowdhury, G; Day, RO; Furlong, T; Graham, GG; Greenfield, JR; Hicks, M; Macdonald, P; Smith, FC; Smith, G; Stocker, SL; Williams, KM, 2019) |
| " Compared to normal controls, untreated burned animals showed decreased hemodynamic parameters, increased serum lactic acid, and severe myocardial inflammation." | 3.79 | Shaking stress aggravates burn-induced cardiovascular and renal disturbances in a rabbit model. ( Chen, YS; Hu, JY; Huang, YS; Lei, ZY; Luo, ZH; Ruan, J; Wang, G; Xiao, R; Zhang, BQ; Zhang, JP, 2013) |
| "The relationship among metformin use, plasma lactate levels, and lactic acidosis in patients with type 2 diabetes mellitus and the appropriateness of metformin use in patients with renal dysfunction are discussed." | 3.75 | Metformin use in renal dysfunction: is a serum creatinine threshold appropriate? ( Ernst, ME; McDanel, DL; Moores, KG; Philbrick, AM; Ross, MB, 2009) |
| " There is currently an unmet need for an efficacious (AMB) formulation amenable to oral administration with better bioavailability and lower nephrotoxicity." | 1.46 | Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats. ( AlQuadeib, BT; Horrocks, B; Radwan, MA; Šiller, L; Wright, MC, 2017) |
| " The nephropathy was induced using intravenous injections of aristolochic acid at a dosage of 10 mg/kg per day for 5 days and was characterized biochemically and histologically." | 1.39 | Urinary d-lactate levels reflect renal function in aristolochic acid-induced nephropathy in mice. ( Chen, SM; Huang, TC; Lee, JA; Li, YC, 2013) |
| "Chloroacetaldehyde toxicity was demonstrated by the decrease in total glutathione and cellular ATP levels." | 1.36 | Targets of chloroacetaldehyde-induced nephrotoxicity. ( Baverel, G; Dubourg, L; Knouzy, B; Michoudet, C, 2010) |
| "The present study demonstrates the potential of EA nanoparticulate formulations in the prevention of CyA-induced nephrotoxicity at three times lower dose suggesting improved oral bioavailability of EA." | 1.34 | Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats. ( Bhardwaj, V; Italia, JL; Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (23.53) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 10 (29.41) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel Shaheed, C | 1 |
| Carland, JE | 1 |
| Graham, GG | 1 |
| Stocker, SL | 1 |
| Smith, G | 1 |
| Hicks, M | 1 |
| Williams, KM | 1 |
| Furlong, T | 1 |
| Macdonald, P | 1 |
| Greenfield, JR | 1 |
| Smith, FC | 1 |
| Chowdhury, G | 1 |
| Day, RO | 1 |
| Chen, SM | 3 |
| Lin, CE | 2 |
| Chen, HH | 1 |
| Cheng, YF | 1 |
| Cheng, HW | 1 |
| Imai, K | 1 |
| Kelemen, JA | 1 |
| Kaserer, A | 1 |
| Jensen, KO | 1 |
| Stein, P | 1 |
| Seifert, B | 1 |
| Simmen, HP | 1 |
| Spahn, DR | 1 |
| Pape, HC | 1 |
| Neuhaus, V | 1 |
| Lin, PY | 1 |
| Yang, WC | 1 |
| Huang, YS | 2 |
| Lin, TY | 1 |
| Chen, CM | 1 |
| Chen, HS | 1 |
| Lee, JA | 2 |
| Huang, TC | 1 |
| Li, YC | 1 |
| Zou, ZJ | 1 |
| Xie, YY | 1 |
| Gong, MJ | 1 |
| Han, B | 1 |
| Wang, SM | 1 |
| Liang, SW | 1 |
| Radwan, MA | 1 |
| AlQuadeib, BT | 1 |
| Šiller, L | 1 |
| Wright, MC | 1 |
| Horrocks, B | 1 |
| Frank, H | 1 |
| Gröger, N | 1 |
| Diener, M | 1 |
| Becker, C | 1 |
| Braun, T | 1 |
| Boettger, T | 1 |
| Lei, R | 1 |
| Wu, C | 1 |
| Yang, B | 1 |
| Ma, H | 1 |
| Shi, C | 1 |
| Wang, Q | 2 |
| Yuan, Y | 1 |
| Liao, M | 1 |
| Huybregts, RA | 1 |
| de Vroege, R | 1 |
| Jansen, EK | 1 |
| van Schijndel, AW | 1 |
| Christiaans, HM | 1 |
| van Oeveren, W | 1 |
| Knouzy, B | 1 |
| Dubourg, L | 1 |
| Baverel, G | 1 |
| Michoudet, C | 1 |
| Philbrick, AM | 1 |
| Ernst, ME | 1 |
| McDanel, DL | 1 |
| Ross, MB | 1 |
| Moores, KG | 1 |
| Müller, HC | 1 |
| Witzenrath, M | 1 |
| Tschernig, T | 1 |
| Gutbier, B | 1 |
| Hippenstiel, S | 1 |
| Santel, A | 1 |
| Suttorp, N | 1 |
| Rosseau, S | 1 |
| Alves, RL | 1 |
| Aragão e Silva, AL | 1 |
| Kraychete, NC | 1 |
| Campos, GO | 1 |
| Martins, Mde J | 1 |
| Módolo, NS | 1 |
| Loor, G | 1 |
| Li, L | 1 |
| Sabik, JF | 1 |
| Rajeswaran, J | 1 |
| Blackstone, EH | 1 |
| Koch, CG | 1 |
| Nishibe, S | 1 |
| Tsujita, M | 1 |
| Wang, G | 1 |
| Zhang, BQ | 1 |
| Ruan, J | 1 |
| Luo, ZH | 1 |
| Zhang, JP | 1 |
| Xiao, R | 1 |
| Lei, ZY | 1 |
| Hu, JY | 1 |
| Chen, YS | 1 |
| HODLER, J | 1 |
| RAMKISSOON, RA | 1 |
| CHAMBERLAIN, NO | 1 |
| BAKER, EL | 1 |
| JENNINGS, ER | 1 |
| Mukhin, NA | 1 |
| Moiseev, VS | 1 |
| Kobalava, ZhD | 1 |
| Moiseev, SV | 1 |
| Fomin, VV | 1 |
| Tyagi, R | 1 |
| Lala, S | 1 |
| Verma, AK | 1 |
| Nandy, AK | 1 |
| Mahato, SB | 1 |
| Maitra, A | 1 |
| Basu, MK | 1 |
| Sonaje, K | 1 |
| Italia, JL | 1 |
| Sharma, G | 1 |
| Bhardwaj, V | 1 |
| Tikoo, K | 1 |
| Kumar, MN | 1 |
| Ditting, T | 1 |
| Hilgers, KF | 1 |
| Stetter, A | 1 |
| Linz, P | 1 |
| Schönweiss, C | 1 |
| Veelken, R | 1 |
| Funk, GC | 1 |
| Paterson, KR | 1 |
| Paice, BJ | 1 |
| Lawson, DH | 1 |
| Goodkin, DA | 1 |
| Krishna, GG | 1 |
| Narins, RG | 1 |
| Bannister, DW | 1 |
| O'Neill, IE | 1 |
| Whitehead, CC | 1 |
| Lewis, NP | 1 |
| Macdougall, IC | 1 |
| Willis, N | 1 |
| Coles, GA | 1 |
| Williams, JD | 1 |
| Henderson, AH | 1 |
| Neiberger, RE | 1 |
| George, JC | 1 |
| Perkins, LA | 1 |
| Theriaque, DW | 1 |
| Hutson, AD | 1 |
| Stacpoole, PW | 1 |
| Munnich, A | 1 |
| Rustin, P | 1 |
| Rötig, A | 1 |
| Chretien, D | 1 |
| Bonnefont, JP | 1 |
| Nuttin, C | 1 |
| Cormier, V | 1 |
| Vassault, A | 1 |
| Parvy, P | 1 |
| Bardet, J | 1 |
| Davenport, A | 1 |
| Will, EJ | 1 |
| Davison, AM | 1 |
| Onwubalili, JK | 1 |
| Bihari, DJ | 1 |
| Gimson, AE | 1 |
| Williams, R | 1 |
| Brezis, M | 1 |
| Rosen, S | 1 |
| Spokes, K | 1 |
| Silva, P | 1 |
| Epstein, FH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for lactic acid and Kidney Diseases
| Article | Year |
|---|---|
Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis.
Topics: Acidosis; Diabetes Mellitus, Type 2; Drug Monitoring; Humans; Hypoglycemic Agents; Kidney; Kidney Di | 2019 |
[Cardiorenal interactions: clinical implication and role in pathogenesis of cardiovascular and renal diseases].
Topics: Atrial Natriuretic Factor; Cardiovascular Diseases; Endothelium; Humans; Kidney Diseases; Lactic Aci | 2004 |
[Stewart's acid-base approach].
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Anions; Bicarbonates; Cations; Diabetic Ketoacidosis; El | 2007 |
Undesired effects of biguanide therapy.
Topics: Acidosis; Biguanides; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Interact | 1984 |
Cardiovascular, pulmonary and renal complications of fulminant hepatic failure.
Topics: Biological Transport; Cardiovascular Diseases; Epoprostenol; Hemodynamics; Hemoglobins; Humans; Kidn | 1986 |
29 other studies available for lactic acid and Kidney Diseases
| Article | Year |
|---|---|
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; F | 2020 |
Prevalence and outcome of contrast-induced nephropathy in major trauma patients.
Topics: Contrast Media; Humans; Incidence; Kidney Diseases; Lactic Acid; Prevalence; Retrospective Studies | 2022 |
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Topics: Animals; Aristolochic Acids; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fibros | 2021 |
Urinary d-lactate levels reflect renal function in aristolochic acid-induced nephropathy in mice.
Topics: Acetylglucosaminidase; Animals; Aristolochic Acids; Creatinine; Female; Histocytochemistry; Kidney; | 2013 |
[Urine metabonomic study of intervention effects of Morinda officinalis how. on 'kidney-yang deficiency syndrome'].
Topics: Alanine; Animals; Betaine; Biomarkers; Citric Acid; Drugs, Chinese Herbal; Hydrocortisone; Ketogluta | 2013 |
Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats.
Topics: Administration, Oral; Amphotericin B; Animals; Antifungal Agents; Biological Availability; Biomarker | 2017 |
Lactaturia and loss of sodium-dependent lactate uptake in the colon of SLC5A8-deficient mice.
Topics: Animals; Butyrates; Carcinogens; Cation Transport Proteins; Cell Transformation, Neoplastic; Colon; | 2008 |
Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: a rapid in vivo screening method for nanotoxicity.
Topics: Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Copper; Drug Evaluation, | 2008 |
The association of hemodilution and transfusion of red blood cells with biochemical markers of splanchnic and renal injury during cardiopulmonary bypass.
Topics: Acetylglucosaminidase; Aged; Biomarkers; Blood Gas Analysis; Cardiopulmonary Bypass; Creatine; Eryth | 2009 |
Targets of chloroacetaldehyde-induced nephrotoxicity.
Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Biotransformation; Enzyme Inhibitors; Enzymes; Glucon | 2010 |
Metformin use in renal dysfunction: is a serum creatinine threshold appropriate?
Topics: Acidosis, Lactic; Creatinine; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Kidney Disease | 2009 |
Adrenomedullin attenuates ventilator-induced lung injury in mice.
Topics: Adrenomedullin; Animals; Bronchodilator Agents; Capillary Permeability; Cytokines; Drug Evaluation, | 2010 |
Intraoperative lactate levels and postoperative complications of pediatric cardiac surgery.
Topics: Adolescent; Blood Gas Analysis; Blood Volume; Cardiac Surgical Procedures; Cardiopulmonary Bypass; C | 2012 |
Nadir hematocrit during cardiopulmonary bypass: end-organ dysfunction and mortality.
Topics: Aged; Anemia; Biomarkers; Cardiopulmonary Bypass; Female; Glomerular Filtration Rate; Heart Diseases | 2012 |
The impact of intraoperative vasopressin infusion in complex neonatal cardiac surgery.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Urea Nitrogen; Cardiac Surgical | 2012 |
Shaking stress aggravates burn-induced cardiovascular and renal disturbances in a rabbit model.
Topics: Animals; Blood Urea Nitrogen; Burns; Cardiovascular Diseases; Creatinine; Disease Models, Animal; Fl | 2013 |
[THE ACTIVITY OF GLUTAMINASE I, TRANSAMINASES AND GLUTAMIC ACID AND LACTIC ACID DEHYDROGENASES IN THE DISEASED HUMAN KIDNEY].
Topics: Alanine Transaminase; Aspartate Aminotransferases; D-Alanine Transaminase; Glomerulonephritis; Gluta | 1964 |
DIAGNOSTIC SIGNIFICANCE OF URINARY LACTIC ACID DEHYDROGENASE.
Topics: Adenocarcinoma; Albuminuria; Carcinoma, Papillary; Carcinoma, Transitional Cell; Clinical Enzyme Tes | 1964 |
Targeted delivery of arjunglucoside I using surface hydrophilic and hydrophobic nanocarriers to combat experimental leishmaniasis.
Topics: Animals; Antiparasitic Agents; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chemistr | 2005 |
Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Antioxidants; Biocompatible Materials; Biological Availability; Cyclo | 2007 |
Renal sympathetic nerves modulate erythropoietin plasma levels after transient hemorrhage in rats.
Topics: Animals; Blood Pressure; Erythropoietin; Hemorrhage; Hypotension; Kidney; Kidney Diseases; Lactic Ac | 2007 |
The role of the anion gap in detecting and managing mixed metabolic acid-base disorders.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis; Alkalosis, Respiratory; Anti-Bacter | 1984 |
The post mortem diagnosis of fatal hypoglycaemia using the fatty liver and kidney syndrome of chicks as a model.
Topics: Animals; Biotin; Blood Glucose; Chickens; Fatty Liver; Glucose; Hypoglycemia; Kidney Diseases; Lacta | 1982 |
Effects of the correction of renal anaemia by erythropoietin on physiological changes during exercise.
Topics: Adolescent; Adult; Aged; Anemia; Bicarbonates; Erythropoietin; Exercise Tolerance; Female; Humans; K | 1993 |
Renal manifestations of congenital lactic acidosis.
Topics: Acidosis, Lactic; Adolescent; Adult; Bicarbonates; Blood Urea Nitrogen; Calcium; Child; Child, Presc | 2002 |
Clinical aspects of mitochondrial disorders.
Topics: Child, Preschool; Coma; Diabetes Mellitus; DNA, Mitochondrial; Dwarfism; Female; Heart Diseases; Hum | 1992 |
Paradoxical increase in arterial hydrogen ion concentration in patients with hepatorenal failure given lactate-based fluids.
Topics: Acid-Base Equilibrium; Aged; Bicarbonates; Blood Pressure; Female; Hemofiltration; Humans; Hydrogen- | 1990 |
Successful peritoneal dialysis using 0.9% sodium chloride with modified M/6 sodium lactate solution and recycled catheters.
Topics: Adolescent; Adult; Aged; Dialysis Solutions; Equipment and Supplies, Hospital; Evaluation Studies as | 1989 |
Substrates induce hypoxic injury to medullary thick limbs of isolated rat kidneys.
Topics: Animals; Glomerular Filtration Rate; Hypoxia; In Vitro Techniques; Kidney Diseases; Kidney Tubules; | 1986 |