lactic acid has been researched along with Injury, Myocardial Reperfusion in 205 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to study (1) the effects of intracoronary saralasin, an angiotensin II receptor antagonist, on ischaemia induced and reperfusion induced regional cardiac noradrenaline release and ventricular arrhythmias; and (2) the implication of angiotensin II in coronary constriction during myocardial ischaemia." | 7.68 | Intracoronary administration of saralasin: effects on cardiac arrhythmias induced by ischaemia and reperfusion in the anaesthetised dog. ( Godin, D; Jetté, L; Nadeau, R; Ribuot, C; Yamaguchi, N, 1992) |
| "For glycerol, there was a further increase at reperfusion." | 5.33 | Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2006) |
| "Levosimendan used throughout myocardial ischemia-reperfusion might have a cardioprotective affect on the response to myocardial ischemia as compared with levosimendan started during the ischemia." | 3.74 | Levosimendan cardioprotection reduces the metabolic response during temporary regional coronary occlusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2007) |
| " The purpose of this study was to assess the effects of felodipine as a potentially protective agent against myocardial ischemia and reperfusion injury, independent of any negative inotropic actions, when given after the onset of low-flow ischemia." | 3.69 | Beneficial effects of felodipine on myocardial and coronary function during low-flow ischemia and reperfusion. ( Apstein, CS; Bernstein, EA; Eberli, FR; Horowitz, GL; Silverman, AM, 1996) |
| "The aim was to study (1) the effects of intracoronary saralasin, an angiotensin II receptor antagonist, on ischaemia induced and reperfusion induced regional cardiac noradrenaline release and ventricular arrhythmias; and (2) the implication of angiotensin II in coronary constriction during myocardial ischaemia." | 3.68 | Intracoronary administration of saralasin: effects on cardiac arrhythmias induced by ischaemia and reperfusion in the anaesthetised dog. ( Godin, D; Jetté, L; Nadeau, R; Ribuot, C; Yamaguchi, N, 1992) |
| "Patients with STEMI treated using PCLeB have reported positive outcomes." | 3.01 | Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans. ( Koyama, T, 2023) |
| "Left ventricular remodeling was ameliorated 28 days after IR, but the treatment did not affect inflammatory monocyte recruitment to the IR heart." | 1.43 | Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening. ( Egashira, K; Funamoto, D; Ikeda, G; Ishikita, A; Matoba, T; Nagaoka, K; Nakano, K; Nakano, Y; Sunagawa, K, 2016) |
| "Cardiovascular protein therapeutics such as neuregulin (NRG1) and acidic-fibroblast growth factor (FGF1) requires new formulation strategies that allow for sustained bioavailability of the drug in the infarcted myocardium." | 1.43 | Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion. ( Abizanda, G; Blanco-Prieto, MJ; de Yebenes, MG; Garbayo, E; Gavira, JJ; Lana, H; Pelacho, B; Prosper, F, 2016) |
| "Development of heart failure is known to be associated with changes in energy substrate metabolism." | 1.39 | Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. ( Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P, 2013) |
| "Carnitine is a vital biologic substance facilitating fatty acids transport into mitochondria for ATP production." | 1.36 | Pharmacological preconditioning with L-carnitine: relevance to myocardial hemodynamic function and glycogen and lactate content. ( Garjani, A; Ghorbani-Haghjo, A; Javidnia, A; Mohammadi, S; Najafi, M, 2010) |
| "Isoflurane has been shown to mimic ischaemic preconditioning (IPC)." | 1.33 | Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion. ( Berenshtein, E; Chevion, M; Drenger, B; Elami, A; Gozal, Y; Kitrossky, N, 2005) |
| "For glycerol, there was a further increase at reperfusion." | 1.33 | Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2006) |
| "It is debated whether brain death (BD) causes transient functional ischemia." | 1.33 | Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs. ( Christé, G; Ferrera, R; Hadour, G; Ovize, M, 2006) |
| "Cardiac function decreased during hemorrhagic shock but improved significantly in the UTI group after transfusion compared with the control group." | 1.32 | Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion. ( Ikeda, KM; Izumi, T; Masuda, T; Matsunaga, A; Matsuyama, N; Nagasawa, H; Noda, C; Ogura, MN; Sato, K; Shimizu, K, 2003) |
| "Trimetazidine is a widely used anti-ischemic agent, but its effect on myocardial preconditioning in anesthetized animals has not been investigated." | 1.32 | Effects of trimetazidine on myocardial preconditioning in anesthetized rats. ( Celik, A; Demiryürek, AT; Demiryürek, S; Kara, AF; Tarakçioğlu, M, 2004) |
| "Early detection of myocardial ischemia is of major importance in critical-care medicine." | 1.31 | An ultrafiltration catheter for monitoring of venous lactate and glucose around myocardial ischemia. ( Hoekstra, A; Korf, J; Tiessen, RG; Tio, RA; Venema, K, 2001) |
| "Glycerol was progressively released during prolonged ischemia." | 1.31 | Monitoring of porcine myocardial ischemia and reperfusion by intravasal microdialysis. ( Bäckström, T; Franco-Cereceda, A; Liska, J; Lockowandt, U; Sylven, C, 2002) |
| "When taurine was additionally applied during reperfusion, EHW recovered to 60%." | 1.29 | Taurine protects the heart from neutrophil-induced reperfusion injury. ( Becker, BF; Massoudy, P; Raschke, P, 1995) |
| "Dilazep was given 5 min before starting ischemia until the end of ischemia." | 1.29 | A study on dilazep: I. Mechanism of anti-ischemic action of dilazep is not coronary vasodilation but decreased cardiac mechanical function in the isolated, working rat heart. ( Abiko, Y; Hashizume, H; Hoque, AN; Hoque, N, 1995) |
| "Captopril (23." | 1.29 | Captopril cardioplegia on myocardial protection in the hypertrophied rat hearts. ( Xu, SC; Zhang, YH, 1994) |
| " Ergothioneine, independently from the dosage used, failed to: (i) increase recovery of developed pressure upon reperfusion (14." | 1.29 | In vitro administration of ergothioneine failed to protect isolated ischaemic and reperfused rabbit heart. ( Bernocchi, P; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R, 1995) |
| "Adenosine appeared to be a more sensitive marker of early ischaemia than lactate, although interestingly, adenosine levels had decreased already after 15 min, most probably due to intracellular accumulation of protons and Pi." | 1.29 | Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig. ( Maripu, E; Nilsson, S; Ronquist, G; Waldenström, A; Wikström, G, 1995) |
| "Quinaprilat and captopril were either subcutaneously injected (0." | 1.29 | Effect of angiotensin converting enzyme inhibition with quinaprilat on the ischaemic and reperfused myocardium. ( Benigno, M; Bernocchi, P; Boraso, A; Cargnoni, A; Ferrari, R; Ghirardelli, N; Pedersini, P; Scotti, C, 1994) |
| "Argimesna is a sulfhydryl group containing molecule which has no effect on glutathione status or on the total thiol pool." | 1.28 | The effects of L-arginine mono(2-mercaptoethanesulfonate) on the ischemic and reperfused heart. ( Boraso, A; Cargnoni, A; Comini, L; De Giuli, F; Ferrari, R; Scotti, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.44) | 18.7374 |
| 1990's | 96 (46.83) | 18.2507 |
| 2000's | 59 (28.78) | 29.6817 |
| 2010's | 43 (20.98) | 24.3611 |
| 2020's | 2 (0.98) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JY | 1 |
| Li, T | 2 |
| Wang, JL | 1 |
| Wang, ZL | 1 |
| Zhang, Y | 1 |
| Zang, LQ | 1 |
| Koyama, T | 2 |
| Herajärvi, J | 1 |
| Anttila, T | 1 |
| Dimova, EY | 1 |
| Laukka, T | 1 |
| Myllymäki, M | 1 |
| Haapanen, H | 1 |
| Olenchock, BA | 1 |
| Tuominen, H | 1 |
| Puistola, U | 1 |
| Karihtala, P | 1 |
| Kiviluoma, K | 1 |
| Koivunen, P | 2 |
| Anttila, V | 1 |
| Juvonen, T | 1 |
| Hermann, R | 1 |
| Mestre Cordero, VE | 1 |
| Fernández Pazos, MLM | 1 |
| Reznik, FJ | 1 |
| Vélez, DE | 1 |
| Savino, EA | 3 |
| Marina Prendes, MG | 1 |
| Varela, A | 3 |
| Boening, A | 2 |
| Assling-Simon, L | 2 |
| Heep, M | 3 |
| Boengler, K | 2 |
| Niemann, B | 3 |
| Grieshaber, P | 2 |
| Schipke, J | 1 |
| Mühlfeld, C | 2 |
| Du, J | 1 |
| Xu, Z | 1 |
| Zhen, J | 1 |
| Liu, J | 1 |
| Yang, D | 1 |
| Zheng, EL | 1 |
| Leng, JY | 1 |
| Favaretto, E | 1 |
| Tarantini, G | 1 |
| Aquaro, GD | 1 |
| Frijia, F | 1 |
| Positano, V | 1 |
| Menichetti, L | 1 |
| Santarelli, MF | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Wiesinger, F | 1 |
| Lionetti, V | 1 |
| Romano, SL | 1 |
| Bianchi, G | 1 |
| Neglia, D | 2 |
| Giovannetti, G | 1 |
| Schulte, RF | 1 |
| Recchia, FA | 1 |
| Landini, L | 1 |
| Lombardi, M | 1 |
| Veljović, M | 1 |
| Popadić, A | 1 |
| Vukić, Z | 1 |
| Ilić, R | 1 |
| Trifunović, Z | 1 |
| Antunović, M | 1 |
| Mandarić, V | 1 |
| Tisma, S | 1 |
| Marković, Z | 1 |
| Zhang, G | 2 |
| Sun, Y | 2 |
| Wang, Y | 2 |
| Li, X | 2 |
| Su, S | 1 |
| Xu, L | 3 |
| Shen, H | 1 |
| Fullmer, TM | 1 |
| Pei, S | 1 |
| Zhu, Y | 2 |
| Sloan, C | 1 |
| Manzanares, R | 1 |
| Henrie, B | 1 |
| Pires, KM | 1 |
| Cox, JE | 1 |
| Abel, ED | 1 |
| Boudina, S | 1 |
| Wu, J | 1 |
| Yuan, SY | 1 |
| Liepinsh, E | 1 |
| Makrecka, M | 1 |
| Kuka, J | 1 |
| Makarova, E | 1 |
| Vilskersts, R | 1 |
| Cirule, H | 1 |
| Sevostjanovs, E | 1 |
| Grinberga, S | 1 |
| Pugovics, O | 1 |
| Dambrova, M | 1 |
| Zhang, GM | 1 |
| Li, XY | 1 |
| Sun, YY | 1 |
| Li, YZ | 1 |
| Liu, LF | 1 |
| Schmidt, MR | 2 |
| Støttrup, NB | 3 |
| Contractor, H | 1 |
| Hyldebrandt, JA | 1 |
| Johannsen, M | 1 |
| Pedersen, CM | 1 |
| Birkler, R | 1 |
| Ashrafian, H | 1 |
| Sørensen, KE | 1 |
| Kharbanda, RK | 2 |
| Redington, AN | 3 |
| Bøtker, HE | 4 |
| Coskun, C | 1 |
| Avci, B | 1 |
| Yalcin, M | 1 |
| Yermezler, A | 1 |
| Yilmaz, MS | 1 |
| Savci, V | 1 |
| Rachmat, J | 1 |
| Sastroasmoro, S | 1 |
| Suyatna, FD | 1 |
| Soejono, G | 1 |
| Böning, A | 1 |
| Hagmüller, S | 1 |
| Rohrbach, S | 1 |
| Gao, S | 1 |
| Zhang, L | 1 |
| Tan, H | 1 |
| Chen, Y | 1 |
| Geng, Y | 1 |
| Lin, Y | 1 |
| Aertker, B | 1 |
| Almashhadany, A | 1 |
| Alghamdi, OA | 1 |
| Van der Touw, T | 1 |
| Jones, GL | 1 |
| King, N | 2 |
| Yang, XY | 1 |
| He, K | 1 |
| Pan, CS | 1 |
| Li, Q | 1 |
| Liu, YY | 1 |
| Yan, L | 1 |
| Wei, XH | 1 |
| Hu, BH | 1 |
| Chang, X | 1 |
| Mao, XW | 1 |
| Huang, DD | 1 |
| Wang, LJ | 1 |
| Hu, SW | 1 |
| Jiang, Y | 1 |
| Wang, GC | 1 |
| Fan, JY | 1 |
| Fan, TP | 1 |
| Han, JY | 1 |
| Ikeda, G | 2 |
| Matoba, T | 3 |
| Nakano, Y | 1 |
| Nagaoka, K | 1 |
| Ishikita, A | 2 |
| Nakano, K | 3 |
| Funamoto, D | 1 |
| Sunagawa, K | 2 |
| Egashira, K | 3 |
| Garbayo, E | 2 |
| Gavira, JJ | 2 |
| de Yebenes, MG | 1 |
| Pelacho, B | 2 |
| Abizanda, G | 2 |
| Lana, H | 1 |
| Blanco-Prieto, MJ | 2 |
| Prosper, F | 2 |
| Koga, J | 2 |
| Mao, Y | 1 |
| Takeuchi, O | 1 |
| Sadoshima, J | 1 |
| Akima, T | 1 |
| Munakata, M | 1 |
| Shibata, M | 1 |
| Moritani, K | 1 |
| Kanki, H | 1 |
| Ishikawa, S | 1 |
| Mitamura, H | 1 |
| Ichimura, K | 1 |
| Tokutome, M | 1 |
| Honda, K | 1 |
| Bruegger, D | 1 |
| Rehm, M | 2 |
| Jacob, M | 2 |
| Chappell, D | 2 |
| Stoeckelhuber, M | 1 |
| Welsch, U | 2 |
| Conzen, P | 2 |
| Becker, BF | 6 |
| Díaz, R | 1 |
| Lorita, J | 1 |
| Soley, M | 1 |
| Ramírez, I | 1 |
| Li, B | 1 |
| Chen, R | 2 |
| Huang, R | 1 |
| Luo, W | 1 |
| Correa, F | 1 |
| García, N | 1 |
| Gallardo-Pérez, J | 1 |
| Carreno-Fuentes, L | 1 |
| Rodríguez-Enríquez, S | 1 |
| Marín-Hernández, A | 1 |
| Zazueta, C | 1 |
| Hofmann-Kiefer, K | 1 |
| Turer, AT | 1 |
| Stevens, RD | 1 |
| Bain, JR | 1 |
| Muehlbauer, MJ | 1 |
| van der Westhuizen, J | 1 |
| Mathew, JP | 1 |
| Schwinn, DA | 1 |
| Glower, DD | 1 |
| Newgard, CB | 1 |
| Podgoreanu, MV | 1 |
| Luo, WJ | 1 |
| Jiang, HH | 1 |
| Long, L | 1 |
| Huang, RM | 1 |
| Luo, FY | 1 |
| Metzsch, C | 3 |
| Linnér, R | 1 |
| Steen, S | 3 |
| Liao, Q | 3 |
| Algotsson, L | 3 |
| Karahalil, B | 1 |
| Gumus, T | 1 |
| Emerce, E | 1 |
| Izdes, S | 1 |
| Kanbak, O | 1 |
| Kesimci, E | 1 |
| Karu, I | 2 |
| Tähepõld, P | 1 |
| Sulling, TA | 1 |
| Alver, M | 1 |
| Zilmer, M | 2 |
| Starkopf, J | 2 |
| Hyvärinen, J | 1 |
| Hassinen, IE | 1 |
| Sormunen, R | 1 |
| Mäki, JM | 1 |
| Kivirikko, KI | 1 |
| Myllyharju, J | 1 |
| Borowski, A | 1 |
| Kurt, M | 1 |
| Calvo, S | 1 |
| Paprotny, G | 1 |
| Godehardt, E | 1 |
| Fraessdorf, J | 1 |
| Ghodsizad, A | 1 |
| Lie, RH | 1 |
| Stoettrup, N | 1 |
| Sloth, E | 1 |
| Hasenkam, JM | 1 |
| Kroyer, R | 1 |
| Nielsen, TT | 1 |
| Najafi, M | 1 |
| Javidnia, A | 1 |
| Ghorbani-Haghjo, A | 1 |
| Mohammadi, S | 1 |
| Garjani, A | 1 |
| Rudd, DM | 1 |
| Dobson, GP | 1 |
| Formiga, FR | 1 |
| Simon-Yarza, T | 1 |
| Mazo, M | 1 |
| Tamayo, E | 1 |
| Jauquicoa, C | 1 |
| Ortiz-de-Solorzano, C | 1 |
| Yamagishi, T | 1 |
| Bessho, M | 1 |
| Yanagida, S | 1 |
| Nishizawa, K | 1 |
| Kusuhara, M | 1 |
| Ohsuzu, F | 1 |
| Tamai, S | 1 |
| Ahlström, K | 1 |
| Biber, B | 1 |
| Åberg, AM | 1 |
| Abrahamsson, P | 1 |
| Johansson, G | 1 |
| Ronquist, G | 3 |
| Waldenström, A | 3 |
| Haney, MF | 1 |
| Alves, MG | 1 |
| Oliveira, PJ | 1 |
| Carvalho, RA | 1 |
| Bao, W | 1 |
| Aravindhan, K | 1 |
| Alsaid, H | 1 |
| Chendrimada, T | 1 |
| Szapacs, M | 1 |
| Citerone, DR | 1 |
| Harpel, MR | 1 |
| Willette, RN | 1 |
| Lepore, JJ | 1 |
| Jucker, BM | 1 |
| Ahlsson, A | 1 |
| Sobrosa, C | 1 |
| Kaijser, L | 1 |
| Jansson, E | 1 |
| Bomfim, V | 1 |
| Michelsen, MM | 1 |
| Løfgren, B | 2 |
| Jensen, RV | 2 |
| Tropak, M | 1 |
| St-Michel, EJ | 1 |
| Onorati, F | 1 |
| Santini, F | 1 |
| Menon, T | 1 |
| Amoncelli, E | 1 |
| Campanella, F | 1 |
| Pechlivanidis, K | 1 |
| Faggian, G | 1 |
| Mazzucco, A | 1 |
| Kristiansen, SB | 1 |
| Dalgas, C | 1 |
| Povlsen, JA | 1 |
| Erichsen, SB | 1 |
| Ahmed, LA | 1 |
| Salem, HA | 1 |
| Mawsouf, MN | 1 |
| Attia, AS | 1 |
| Agha, AM | 1 |
| Zhabyeyev, P | 1 |
| Gandhi, M | 1 |
| Mori, J | 1 |
| Basu, R | 1 |
| Kassiri, Z | 1 |
| Clanachan, A | 1 |
| Lopaschuk, GD | 1 |
| Oudit, GY | 1 |
| Zou, Z | 1 |
| Sasaguri, S | 1 |
| Rajesh, KG | 1 |
| Suzuki, R | 1 |
| Eynan, M | 1 |
| Knubuvetz, T | 1 |
| Meiri, U | 1 |
| Navon, G | 1 |
| Gerstenblith, G | 1 |
| Bromberg, Z | 1 |
| Hasin, Y | 1 |
| Horowitz, M | 1 |
| Cerruti, S | 1 |
| Testoni, G | 1 |
| Dalamon, V | 1 |
| Kade, P | 1 |
| Canbaz, S | 1 |
| Duran, E | 1 |
| Ege, T | 1 |
| Sunar, H | 1 |
| Cikirikcioglu, M | 1 |
| Acipayam, M | 1 |
| Masuda, T | 1 |
| Sato, K | 1 |
| Noda, C | 1 |
| Ikeda, KM | 1 |
| Matsunaga, A | 1 |
| Ogura, MN | 1 |
| Shimizu, K | 1 |
| Nagasawa, H | 1 |
| Matsuyama, N | 1 |
| Izumi, T | 1 |
| Lin, H | 2 |
| Suleiman, MS | 7 |
| Kobara, M | 2 |
| Tatsumi, T | 2 |
| Takeda, M | 1 |
| Mano, A | 1 |
| Yamanaka, S | 1 |
| Shiraishi, J | 1 |
| Keira, N | 1 |
| Matoba, S | 2 |
| Asayama, J | 2 |
| Nakagawa, M | 2 |
| Louagie, YA | 1 |
| Jamart, J | 1 |
| Gonzalez, M | 2 |
| Collard, E | 1 |
| Broka, S | 1 |
| Galanti, L | 1 |
| Gruslin, A | 1 |
| Muscari, C | 1 |
| Gamberini, C | 1 |
| Bonafe', F | 1 |
| Giordano, E | 1 |
| Bianchi, C | 1 |
| Lenaz, G | 1 |
| Caldarera, CM | 1 |
| Modi, P | 1 |
| Reeves, B | 1 |
| Pawade, A | 1 |
| Parry, AJ | 1 |
| Angelini, GD | 4 |
| Caputo, M | 4 |
| Kara, AF | 1 |
| Demiryürek, S | 1 |
| Celik, A | 1 |
| Tarakçioğlu, M | 1 |
| Demiryürek, AT | 1 |
| Yoshikawa, Y | 1 |
| Hagihara, H | 1 |
| Ohga, Y | 1 |
| Nakajima-Takenaka, C | 1 |
| Murata, KY | 1 |
| Taniguchi, S | 1 |
| Takaki, M | 1 |
| Wang, P | 1 |
| Lloyd, SG | 1 |
| Zeng, H | 1 |
| Bonen, A | 1 |
| Chatham, JC | 1 |
| Pantos, C | 1 |
| Bescond-Jacquet, A | 1 |
| Tzeis, S | 1 |
| Paizis, I | 1 |
| Mourouzis, I | 1 |
| Moraitis, P | 1 |
| Malliopoulou, V | 1 |
| Politi, ED | 1 |
| Karageorgiou, H | 1 |
| Varonos, D | 1 |
| Cokkinos, DV | 1 |
| Lu, J | 1 |
| Zang, WJ | 1 |
| Yu, XJ | 1 |
| Chen, LN | 1 |
| Zhang, CH | 1 |
| Jia, B | 1 |
| Morán, M | 1 |
| Blázquez, I | 1 |
| Saborido, A | 1 |
| Megías, A | 1 |
| Gozal, Y | 1 |
| Chevion, M | 1 |
| Elami, A | 1 |
| Berenshtein, E | 1 |
| Kitrossky, N | 1 |
| Drenger, B | 1 |
| Kitagawa, H | 1 |
| Yamazaki, T | 1 |
| Akiyama, T | 1 |
| Sugimachi, M | 1 |
| Mori, H | 1 |
| McGivan, JD | 1 |
| Christé, G | 1 |
| Hadour, G | 1 |
| Ovize, M | 1 |
| Ferrera, R | 1 |
| Li, J | 1 |
| Konstantinov, IE | 1 |
| Cheung, MM | 1 |
| White, PA | 1 |
| Frndova, H | 1 |
| Stokoe, J | 1 |
| Cox, P | 1 |
| Vogel, M | 1 |
| Van Arsdell, G | 1 |
| MacAllister, R | 1 |
| Savaşkan, D | 1 |
| Yurtseven, N | 1 |
| Tuygun, AK | 1 |
| Aksoy, P | 1 |
| Canik, S | 1 |
| Gökşin, I | 1 |
| Gonsolin, D | 1 |
| Couturier, K | 1 |
| Garait, B | 1 |
| Rondel, S | 1 |
| Novel-Chaté, V | 1 |
| Peltier, S | 1 |
| Faure, P | 1 |
| Gachon, P | 1 |
| Boirie, Y | 1 |
| Keriel, C | 1 |
| Favier, R | 1 |
| Pepe, S | 1 |
| Demaison, L | 1 |
| Leverve, X | 1 |
| Podesser, BK | 1 |
| Jain, M | 1 |
| Ngoy, S | 1 |
| Apstein, CS | 3 |
| Eberli, FR | 2 |
| Constantinou, MA | 1 |
| Tsantili-Kakoulidou, A | 1 |
| Andreadou, I | 1 |
| Iliodromitis, EK | 1 |
| Kremastinos, DT | 1 |
| Mikros, E | 1 |
| Barillas, R | 1 |
| Friehs, I | 1 |
| Cao-Danh, H | 1 |
| Martinez, JF | 1 |
| del Nido, PJ | 1 |
| Hudorovic, N | 1 |
| L'Abbate, A | 1 |
| Vecoli, C | 1 |
| Novelli, M | 1 |
| Ottaviano, V | 1 |
| Baldi, S | 1 |
| Barsacchi, R | 1 |
| Paolicchi, A | 1 |
| Masiello, P | 1 |
| Drummond, GS | 1 |
| McClung, JA | 1 |
| Abraham, NG | 1 |
| Prendes, MG | 1 |
| Torresín, E | 1 |
| Fernández, MA | 1 |
| Perazzo, JC | 1 |
| Loit, R | 1 |
| Zilmer, K | 1 |
| Kairane, C | 1 |
| Paapstel, A | 1 |
| McDonough, KH | 1 |
| Giaimo, ME | 1 |
| Miller, HI | 1 |
| de Groot, MJ | 1 |
| van Helden, MA | 1 |
| de Jong, YF | 1 |
| Coumans, WA | 2 |
| van der Vusse, GJ | 3 |
| Schulz, R | 2 |
| Wambolt, R | 1 |
| Raschke, P | 1 |
| Massoudy, P | 3 |
| Asimakis, GK | 1 |
| Conti, VR | 1 |
| Hoque, AN | 3 |
| Hoque, N | 2 |
| Hashizume, H | 2 |
| Abiko, Y | 4 |
| Mezzetti, A | 1 |
| Calafiore, AM | 2 |
| Lapenna, D | 1 |
| Deslauriers, R | 1 |
| Tian, G | 1 |
| Salerno, TA | 1 |
| Verna, AM | 1 |
| Bosco, G | 1 |
| Pierdomenico, SD | 1 |
| Caccurullo, F | 1 |
| Zhang, YH | 1 |
| Xu, SC | 1 |
| Cargnoni, A | 4 |
| Bernocchi, P | 2 |
| Ceconi, C | 2 |
| Curello, S | 2 |
| Ferrari, R | 4 |
| Isomura, T | 2 |
| Hisatomi, K | 1 |
| Sato, T | 1 |
| Hayashida, N | 3 |
| Ohishi, K | 1 |
| Moolman, JA | 1 |
| Genade, S | 1 |
| Winterbach, R | 1 |
| Harper, IS | 1 |
| Williams, K | 1 |
| Lochner, A | 1 |
| Wikström, G | 2 |
| Nilsson, S | 1 |
| Maripu, E | 1 |
| Seligmann, C | 1 |
| Gerlach, E | 1 |
| McGrath, LB | 1 |
| Locke, M | 1 |
| Cane, M | 1 |
| Chen, C | 1 |
| Ianuzzo, CD | 1 |
| Woolfson, RG | 1 |
| Patel, VC | 1 |
| Neild, GH | 1 |
| Yellon, DM | 2 |
| Hoffmann, P | 1 |
| Klapperstück, M | 1 |
| Scholz, J | 1 |
| Weise, M | 1 |
| Döpfer, KP | 1 |
| Seth, SD | 2 |
| Maulik, M | 2 |
| Manchanda, SC | 2 |
| Maulik, SK | 2 |
| Hudspeth, DA | 1 |
| Williams, MW | 1 |
| Zhao, ZQ | 1 |
| Sato, H | 1 |
| Nakanishi, K | 1 |
| McGee, DS | 1 |
| Hammon, JW | 1 |
| Vinten-Johansen, J | 1 |
| Van Wylen, DG | 2 |
| Myrmel, T | 2 |
| McCully, JD | 1 |
| Malikin, L | 1 |
| Krukenkamp, IB | 1 |
| Levitsky, S | 1 |
| Stahl, RF | 1 |
| Soller, BR | 1 |
| Hsi, C | 1 |
| BelleIsle, J | 1 |
| Vander Salm, TJ | 1 |
| Golden, AL | 1 |
| Bright, JM | 1 |
| Pohost, GM | 1 |
| Pike, MM | 1 |
| Schjøtt, J | 1 |
| Jynge, P | 1 |
| Holten, T | 1 |
| Brurok, H | 1 |
| Kumerova, AO | 1 |
| Shkesters, AP | 1 |
| Shkestere, IIa | 1 |
| Vanoverschelde, JL | 1 |
| Janier, MF | 1 |
| Bergmann, SR | 1 |
| Boraso, A | 2 |
| Scotti, C | 2 |
| Ghirardelli, N | 1 |
| Benigno, M | 1 |
| Pedersini, P | 1 |
| Karmazyn, M | 2 |
| Moffat, MP | 1 |
| Hendrikx, M | 1 |
| Toshima, Y | 1 |
| Mubagwa, K | 1 |
| Flameng, W | 2 |
| Subramanian, R | 2 |
| Volovsek, A | 2 |
| Ho, YS | 1 |
| Bing, OH | 1 |
| Kihara, Y | 1 |
| Brooks, WW | 1 |
| Conrad, CH | 1 |
| Morgan, JP | 1 |
| Ikonomidis, JS | 4 |
| Yau, TM | 3 |
| Weisel, RD | 9 |
| Fu, X | 1 |
| Komeda, M | 2 |
| Ivanov, J | 6 |
| Carson, S | 3 |
| Mohabeer, MK | 3 |
| Tumiati, L | 2 |
| Shizukuda, Y | 1 |
| Iwamoto, T | 1 |
| Mallet, RT | 1 |
| Downey, HF | 1 |
| Alkhulaifi, AM | 1 |
| Pugsley, WB | 1 |
| Mickle, DA | 7 |
| Liu, P | 1 |
| Tani, M | 4 |
| Neely, JR | 1 |
| Yamahara, Y | 1 |
| Nakagawa, C | 1 |
| Ohta, B | 1 |
| Matsumoto, T | 1 |
| Inoue, D | 1 |
| Beresewicz, A | 1 |
| Karwatowska-Prokopczuk, E | 1 |
| Lewartowski, B | 1 |
| Cedro-Ceremuåzyńska, K | 1 |
| Bical, OM | 1 |
| Gerhardt, MF | 1 |
| Paumier, D | 1 |
| Gaillard, D | 1 |
| Landais, P | 1 |
| Fromes, Y | 1 |
| Foiret, JC | 1 |
| Trivin, F | 1 |
| Vanetti, A | 1 |
| Haessler, R | 1 |
| Davis, RF | 1 |
| Wolff, RA | 2 |
| Kozume, K | 1 |
| Shangraw, R | 1 |
| Van Winkle, DM | 2 |
| Bernstein, EA | 1 |
| Silverman, AM | 1 |
| Horowitz, GL | 1 |
| Anderson, KE | 1 |
| Du, XJ | 1 |
| Sinclair, AJ | 1 |
| Woodcock, EA | 1 |
| Dart, AM | 1 |
| Kamlot, A | 1 |
| Bellows, SD | 1 |
| Simkhovich, BZ | 1 |
| Hale, SL | 1 |
| Aoki, A | 1 |
| Kloner, RA | 1 |
| Kay, GL | 1 |
| McNulty, PH | 1 |
| Darling, A | 1 |
| Whiting, JM | 1 |
| Moffatt, AC | 1 |
| Dihmis, WC | 2 |
| Hutter, JA | 1 |
| Bryan, AJ | 3 |
| Nicholson, SC | 1 |
| Squier, M | 1 |
| Ferguson, DJ | 1 |
| Nagy, Z | 1 |
| Westaby, S | 1 |
| Evans, RD | 1 |
| Ando, H | 1 |
| Tanaka, J | 1 |
| Hisahara, M | 1 |
| Nagano, I | 1 |
| Shimizu, I | 1 |
| Rao, V | 5 |
| Feindel, CM | 1 |
| Boylen, P | 1 |
| Cohen, G | 4 |
| Takeda, H | 1 |
| Haneda, T | 1 |
| Kikuchi, K | 1 |
| Shibata, E | 1 |
| Andou, F | 1 |
| Akagawa, H | 1 |
| Yanagi, I | 1 |
| Shima, H | 1 |
| Yamashita, M | 1 |
| Ouryouji, A | 1 |
| Hara, H | 1 |
| Kosuga, K | 1 |
| Shirai, T | 2 |
| Li, RK | 2 |
| Tumiati, LC | 4 |
| Merante, F | 2 |
| Shiono, N | 2 |
| Nonami, Y | 1 |
| Carson, SM | 1 |
| Borger, MA | 2 |
| Cusimano, RJ | 1 |
| Yabe, K | 1 |
| Takeo, S | 1 |
| Suganuma, Y | 1 |
| Takayama, M | 1 |
| Hasegawa, H | 2 |
| Shinmura, K | 1 |
| Ebihara, Y | 1 |
| Tamaki, K | 1 |
| de Jonge, R | 1 |
| Bradamante, S | 1 |
| Speleman, L | 1 |
| Willem de Jong, J | 1 |
| Schöder, H | 2 |
| Knight, RJ | 2 |
| Kofoed, KF | 2 |
| Schelbert, HR | 1 |
| Buxton, DB | 2 |
| Dote, K | 1 |
| Robinson, BH | 1 |
| El Banani, H | 1 |
| Bernard, M | 1 |
| Cozzone, P | 1 |
| James, F | 1 |
| Feuvray, D | 1 |
| Habicht, JM | 1 |
| Wolff, T | 1 |
| Langemann, H | 1 |
| Stulz, P | 1 |
| Zmudka, K | 1 |
| Dubiel, J | 1 |
| Pieniazek, P | 1 |
| Dudek, D | 1 |
| Kocurek, A | 1 |
| Trebacz, J | 1 |
| Grodecki, J | 1 |
| de Geest, H | 1 |
| Abe, K | 1 |
| Hayashi, N | 1 |
| Terada, H | 1 |
| Kerr, PM | 1 |
| Halestrap, AP | 1 |
| Hartl, H | 1 |
| Zahler, S | 1 |
| Braun, S | 1 |
| Barankay, A | 1 |
| Meisner, H | 1 |
| Habazettl, H | 1 |
| Voigtländer, J | 1 |
| Mühlbayer, D | 1 |
| Pietersen, HG | 1 |
| Langenberg, CJ | 1 |
| Geskes, G | 1 |
| Kester, A | 1 |
| de Lange, S | 1 |
| Wagenmakers, AJ | 1 |
| Soeters, PB | 1 |
| Du Toit, EF | 1 |
| Muller, CA | 1 |
| McCarthy, J | 1 |
| Opie, LH | 1 |
| Maddaford, TG | 1 |
| Hurtado, C | 1 |
| Sobrattee, S | 1 |
| Czubryt, MP | 1 |
| Pierce, GN | 1 |
| Ladilov, YV | 1 |
| Balser-Schäfer, C | 1 |
| Haffner, S | 1 |
| Maxeiner, H | 1 |
| Piper, HM | 1 |
| Möbert, J | 1 |
| Nomura, F | 2 |
| Aoki, M | 1 |
| Forbess, JM | 2 |
| Mayer, JE | 1 |
| Tomoeda, H | 1 |
| Oda, T | 1 |
| Tayama, E | 1 |
| Chihara, S | 1 |
| Akasu, K | 1 |
| Kosuga, T | 1 |
| Kai, E | 1 |
| Aoyagi, S | 1 |
| Kjellman, UW | 1 |
| Björk, K | 1 |
| Dahlin, A | 1 |
| Ekroth, R | 1 |
| Kirnö, K | 1 |
| Svensson, G | 1 |
| Wernerman, J | 1 |
| Hayashi, Y | 1 |
| Tajima, K | 1 |
| Kirimoto, T | 1 |
| Miyake, H | 1 |
| Matsuura, N | 1 |
| Mayer, EJ | 1 |
| Ravingerova, T | 1 |
| Neckar, J | 1 |
| Kolar, F | 1 |
| Stetka, R | 1 |
| Volkovova, K | 1 |
| Ziegelhöffer, A | 1 |
| Styk, J | 1 |
| Tiessen, RG | 1 |
| Tio, RA | 1 |
| Hoekstra, A | 1 |
| Venema, K | 1 |
| Korf, J | 1 |
| De Windt, LJ | 1 |
| Willems, J | 1 |
| Roemen, TH | 1 |
| Reneman, RS | 1 |
| Van Bilsen, M | 1 |
| Dawn, B | 1 |
| Bolli, R | 1 |
| Korvald, C | 1 |
| Elvenes, OP | 1 |
| Aghajani, E | 1 |
| Myhre, ES | 1 |
| Yamamura, K | 1 |
| Gen, W | 1 |
| Zemgulis, V | 1 |
| Bjerner, T | 1 |
| Henze, A | 1 |
| Lahtinen, M | 1 |
| Thelin, S | 1 |
| Crittenden, MD | 1 |
| Khandoudi, N | 1 |
| Delerive, P | 1 |
| Berrebi-Bertrand, I | 1 |
| Buckingham, RE | 1 |
| Staels, B | 1 |
| Bril, A | 1 |
| Bäckström, T | 1 |
| Lockowandt, U | 1 |
| Liska, J | 1 |
| Sylven, C | 1 |
| Franco-Cereceda, A | 1 |
| Corno, AF | 1 |
| Milano, G | 1 |
| Samaja, M | 1 |
| Tozzi, P | 1 |
| von Segesser, LK | 1 |
| Ehring, T | 1 |
| Heusch, G | 1 |
| Bagchi, D | 1 |
| Bagchi, M | 1 |
| Douglas, DM | 1 |
| Das, DK | 1 |
| Fabián, J | 1 |
| Popovic, Z | 1 |
| Vucinic, M | 1 |
| Sherry, AD | 1 |
| Malloy, CR | 1 |
| Zhao, P | 1 |
| Thompson, JR | 1 |
| Poltronieri, R | 1 |
| Cevese, A | 1 |
| Sbarbati, A | 1 |
| Comini, L | 1 |
| De Giuli, F | 1 |
| Reboussin, D | 1 |
| McFalls, EO | 1 |
| Duncker, DJ | 1 |
| Krams, R | 1 |
| Sassen, LM | 1 |
| Hoogendoorn, A | 1 |
| Verdouw, PD | 1 |
| Ribuot, C | 1 |
| Yamaguchi, N | 1 |
| Godin, D | 1 |
| Jetté, L | 1 |
| Nadeau, R | 1 |
| Nasa, Y | 2 |
| Ichihara, K | 2 |
| Downing, SE | 1 |
| Chen, V | 1 |
| Mergner, GW | 1 |
| Weglicki, WB | 1 |
| Kramer, JH | 1 |
| Wittnich, C | 1 |
| Maitland, A | 1 |
| Vincente, W | 1 |
| Salerno, T | 1 |
| Bengtsson, L | 1 |
| Gunnes, S | 1 |
| Norman, B | 1 |
| Karlsson, J | 1 |
| Julia, P | 1 |
| Kofsky, ER | 1 |
| Buckberg, GD | 1 |
| Young, HH | 1 |
| Bugyi, HI | 1 |
| Keller, AM | 1 |
| Cannon, PJ | 1 |
| Boffa, GM | 1 |
| Gaasch, WH | 1 |
| Zile, MR | 1 |
| Hoshino, PK | 1 |
| Weinberg, EO | 1 |
| Rhodes, DR | 1 |
| Cavallini, L | 1 |
| Valente, M | 1 |
| Rigobello, MP | 1 |
| Geisbuhler, TP | 1 |
| Rovetto, MJ | 1 |
| Vavrínková, H | 1 |
| Tutterová, M | 1 |
| Vránová, Z | 1 |
| van der Kraaij, AM | 1 |
| van Eijk, HG | 1 |
| Koster, JF | 1 |
| Sochor, H | 1 |
| Finkle, CD | 1 |
| Madonik, MM | 1 |
| Burton, GW | 1 |
| Ingold, KU | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Peri-Operative Intravenous Estrogen for the Mitigation of Ischemia Reperfusion Injury in the Setting of Renal Transplantation[NCT03663543] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2016-08-26 | Active, not recruiting | ||
| The Effect of Adenosine on Myocardial Protection in Intermittent Warm Blood Cardioplegia: A Randomized Placebo-controlled Trial[NCT02681913] | Phase 2 | 100 participants (Anticipated) | Interventional | 2016-02-29 | Recruiting | ||
| A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Ischemic Preconditioning for Prevention of Contrast Nephropathy in The Emergency Department: Randomised, Double Blind Clinical Trial[NCT03238391] | 350 participants (Anticipated) | Interventional | 2017-08-15 | Not yet recruiting | |||
| Effect of Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery[NCT03016182] | 60 participants (Anticipated) | Interventional | 2017-02-07 | Recruiting | |||
| A Clinical Study Investigating Ischemic Preconditioning in Type II Diabetic Patients Undergoing Coronary Artery Bypass Graft Surgery.[NCT00397163] | Phase 1 | 200 participants (Anticipated) | Interventional | 2010-12-31 | Completed | ||
| Conservative vs Conventional Oxygen Administration in Critically Ill Patients: Effects on ICU Mortality. A Multicentre Randomized Open Label Clinical Trial[NCT04198077] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2019-12-04 | Recruiting | ||
| Clinical and Ultramicroscopic Myocardial Randomized Study of On-Pump Beating Heart Mitral Valve Replacement[NCT01641614] | Phase 4 | 34 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| A Double-Blind, Placebo-Controlled Trial of Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment: Bergman's Minimal Model Analysis[NCT00337350] | Phase 4 | 20 participants (Actual) | Interventional | 2003-09-30 | Completed | ||
| Attenuation of Myocardial Dysfunction by N-Acetylcysteine in Infants Undergoing Arterial Switch Procedure[NCT00374088] | Phase 2 | 21 participants (Actual) | Interventional | 2005-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Acute insulin response to glucose (AIRG) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in SG between Baseline and week 8. AIRG was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. AIRG measures the acute(0-10 min) beta cell response to a glucose load calculated by the areas under the curve higher than basal insulin values. The AIRG was assessed as the incremental area under the curve (calculated by the trapezoid rule) from 0 to 10 min of the FSIVGTT. (NCT00337350)
Timeframe: baseline, week 8
| Intervention | Units/mL per 10 minutes (Mean) |
|---|---|
| Rosiglitazone | -151 |
| Placebo | 19 |
Insulin Sensitivity (IS) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in IS between Baseline and week 8. SI was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. SI represents the increase in net fractional glucose clearance rate per unit change in serum insulin concentration after the intravenous glucose load (microUnits/mL). (NCT00337350)
Timeframe: baseline, week 8
| Intervention | microUnits/mL (Mean) |
|---|---|
| Rosiglitazone | 3.2 |
| Placebo | 0.4 |
Glucose utilization (SG) was assessed using a Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT), performed at Baseline and at week 8 (study endpoint). Subjects in the Rosiglitazone treatment arm were compared to subjects in the placebo treatment arm on their change in SG between Baseline and week 8. SG was calculated from plasma glucose and serum insulin values using the MINMOD Millennium computer program. SG represents the net fractional glucose clearance rate because of the increase in glucose independent of any increase in circulating insulin concentrations above baseline. (NCT00337350)
Timeframe: baseline, week 8
| Intervention | min^-1 (Mean) |
|---|---|
| Rosiglitazone | .002 |
| Placebo | -0.01 |
Maximum serum creatinine over first 3 days postoperative. (NCT00374088)
Timeframe: 72 hours
| Intervention | mg/dL (Mean) |
|---|---|
| Placebo | 0.99 |
| N-acetylcysteine | 0.74 |
Serial cardiac output was measured by thermodilution. The outcome of maximum decline in indexed cardiac output from 1 hour postoperative to lowest output within 24 hours postoperative was then calculated and compared between NAC and placebo groups. (NCT00374088)
Timeframe: 24 hours
| Intervention | L/min/m2 (Mean) |
|---|---|
| Placebo | 0.68 |
| N-acetylcysteine | 0.29 |
Total urine output over the first 24 hours postoperative (NCT00374088)
Timeframe: 24 hours
| Intervention | mL (Mean) |
|---|---|
| Placebo | 96 |
| N-acetylcysteine | 176 |
3 reviews available for lactic acid and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans.
Topics: Humans; Lactic Acid; Myocardial Reperfusion Injury; ST Elevation Myocardial Infarction | 2023 |
Role of Na+/H+ exchange in cardiac physiology and pathophysiology: mediation of myocardial reperfusion injury by the pH paradox.
Topics: Animals; Arrhythmias, Cardiac; Blood Platelets; Calcium; Heart; Humans; Hydrogen-Ion Concentration; | 1993 |
Characterization of "hibernating" and "stunned" myocardium with focus on the use of calcium antagonists in "stunned" myocardium.
Topics: Calcium; Calcium Channel Blockers; Coronary Circulation; Humans; Lactates; Lactic Acid; Myocardial C | 1992 |
21 trials available for lactic acid and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Myocardial protection during elective coronary artery bypasses grafting by pretreatment with omega-3 polyunsaturated fatty acids.
Topics: Coronary Artery Bypass; Elective Surgical Procedures; Fatty Acids, Omega-3; Female; Humans; Infusion | 2013 |
Clinical benefit of cardiac ischemic postconditioning in corrections of tetralogy of Fallot.
Topics: Adolescent; Aorta; Cardiac Surgical Procedures; Cardiotonic Agents; Child; Child, Preschool; Constri | 2009 |
[Cardiopulmonary protection of ischemic postconditioning in cardiac surgery in children with tetralogy of Fallot].
Topics: Adolescent; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child, Preschool; Female; He | 2009 |
Adenosine in cold blood cardioplegia--a placebo-controlled study.
Topics: Adenine Nucleotides; Adenosine; Aged; Biopsy; Cold Temperature; Dose-Response Relationship, Drug; Do | 2012 |
Leukocyte filtration of blood cardioplegia attenuates myocardial damage and inflammation.
Topics: Aged; Analysis of Variance; Aortic Valve; Aortic Valve Stenosis; Cytokines; Female; Heart Arrest, In | 2013 |
The effects of intracoronary administration of vitamin E on myocardial ischemia-reperfusion injury during coronary artery surgery.
Topics: Aged; Antioxidants; Biomarkers; Blood Gas Analysis; Coronary Artery Bypass; Creatine Kinase; Creatin | 2003 |
Continuous cold blood cardioplegia improves myocardial protection: a prospective randomized study.
Topics: Aged; Cardiopulmonary Bypass; Coronary Disease; Energy Metabolism; Female; Heart Arrest, Induced; He | 2004 |
Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biomarkers; Cardiac Surgical Procedures; Child; Child | 2004 |
[The effects of insulin given prior to release of cross-clamp on coronary sinus lactate levels in coronary artery surgery].
Topics: Adult; Aged; Coronary Artery Bypass; Drug Administration Schedule; Female; Humans; Hypoglycemic Agen | 2006 |
Pre-treatment with hyperoxia before coronary artery bypass grafting - effects on myocardial injury and inflammatory response.
Topics: Coronary Artery Bypass; Creatine Kinase; Female; Hemodynamics; Humans; Hyperoxia; Inflammation; Inte | 2007 |
Intermittent antegrade warm cardioplegia reduces oxidative stress and improves metabolism of the ischemic-reperfused human myocardium.
Topics: Aged; Creatine Kinase; Female; Glutathione; Heart Arrest, Induced; Humans; Lactates; Lactic Acid; Li | 1995 |
Optimal flow rates for retrograde warm cardioplegia.
Topics: Adult; Aged; Blood; Cardioplegic Solutions; Coronary Artery Bypass; Female; Heart Arrest, Induced; H | 1994 |
Ventricular function after normothermic versus hypothermic cardioplegia.
Topics: Adenine Nucleotides; Blood; Cardioplegic Solutions; Coronary Artery Bypass; Female; Heart Arrest, In | 1993 |
Effects of two different crystalloid cardioplegic solutions assessed by myocardial pH, tissue lactate content and energy metabolism.
Topics: Acid-Base Equilibrium; Aged; Bicarbonates; Biopsy; Calcium Chloride; Cardioplegic Solutions; Energy | 1996 |
Optimal flow rates for integrated cardioplegia.
Topics: Blood; Cardioplegic Solutions; Cardiopulmonary Bypass; Coronary Artery Bypass; Heart Arrest, Induced | 1998 |
Warm blood hyperkalaemic reperfusion ('hot shot') prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery.
Topics: Adenosine Triphosphate; Amino Acids; Bicarbonates; Blood; Calcium Chloride; Cardioplegic Solutions; | 1998 |
Intermittent antegrade hyperkalaemic warm blood cardioplegia supplemented with magnesium prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery.
Topics: Adenosine Triphosphate; Amino Acids; Biopsy; Blood; Calcium Channel Blockers; Cardioplegic Solutions | 1998 |
[Plasma lactate concentration in post-ischemic reperfusion of human hearts under treatment with sodium nitroprusside].
Topics: Aged; Anesthesia; Biomarkers; Chromatography, High Pressure Liquid; Female; Glutathione; Humans; Lac | 1999 |
Insulin(GIK) improves myocardial metabolism in patients during blood cardioplegia.
Topics: Aged; Amino Acids; Cardioplegic Solutions; Citric Acid Cycle; Coronary Artery Bypass; Energy Metabol | 2000 |
The effect of allopurinol on free oxygen radicals in myocardial reperfusion.
Topics: Administration, Oral; Allopurinol; Coronary Artery Bypass; Coronary Circulation; Creatine Kinase; Fe | 1992 |
Alternative techniques of cardioplegia.
Topics: Adenosine Triphosphate; Blood; Coronary Artery Bypass; Creatine Kinase; Female; Heart Arrest, Induce | 1992 |
181 other studies available for lactic acid and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Protective Effects and Mechanisms of Melatonin on Stress Myocardial Injury in Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Body Weight; Caspase 3; Creatine Kina | 2022 |
Exploring effects of remote ischemic preconditioning in a pig model of hypothermic circulatory arrest.
Topics: Animals; Antioxidants; Biomarkers; Brain; Cardiopulmonary Bypass; Circulatory Arrest, Deep Hypotherm | 2017 |
Differential effects of AMP-activated protein kinase in isolated rat atria subjected to simulated ischemia-reperfusion depending on the energetic substrates available.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; Animals; Atrial Function; Energy Metab | 2018 |
Buckberg's blood cardioplegia for protection of adult and senile myocardium in a rat in vitro model of acute myocardial infarction.
Topics: Analysis of Variance; Animals; Aorta; Cardioplegic Solutions; Constriction; Coronary Vessels; Diseas | 2018 |
Blood cardioplegia for cardiac surgery in acute myocardial infarction: rat experiments with two widely used solutions.
Topics: Animals; Cardiac Surgical Procedures; Cardioplegic Solutions; Disease Models, Animal; Heart Arrest, | 2018 |
Dexmedetomidine attenuates myocardial ischemia/reperfusion injury through regulating lactate signaling cascade in mice.
Topics: Animals; Caspase 3; Caspase 9; Coronary Vessels; Cytochromes c; Dexmedetomidine; Disease Models, Ani | 2019 |
Acidic postconditioning in ST-elevation myocardial infarction patients.
Topics: Angioplasty, Balloon, Coronary; Female; Humans; Ischemic Preconditioning, Myocardial; Isotonic Solut | 2013 |
3D CMR mapping of metabolism by hyperpolarized 13C-pyruvate in ischemia-reperfusion.
Topics: Animals; Carbon Isotopes; Disease Models, Animal; Energy Metabolism; Feasibility Studies; Image Inte | 2013 |
Local administration of lactic acid and a low dose of the free radical scavenger, edaravone, alleviates myocardial reperfusion injury in rats.
Topics: Animals; Antipyrine; Apoptosis; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers | 2013 |
Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms.
Topics: Animals; Cardiotonic Agents; Glycogen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; | 2013 |
MCT1 and MCT4 expression during myocardial ischemic-reperfusion injury in the isolated rat heart.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Basigin; Heart; In Vitro Techniques; L-Lactate De | 2013 |
The heart is better protected against myocardial infarction in the fed state compared to the fasted state.
Topics: Animals; Blood Glucose; Blotting, Western; Caloric Restriction; Energy Metabolism; Fasting; Fatty Ac | 2014 |
[Pharmacological postconditioning with lactic acid and low dose edaravone could attenuate myocardial reperfusion injury through mitochondrial pathway].
Topics: Animals; Antipyrine; Apoptosis; Cytochromes c; Disease Models, Animal; Edaravone; Ischemic Postcondi | 2013 |
Remote ischemic preconditioning with--but not without--metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury.
Topics: Animals; Animals, Newborn; Glucose; Hypoglycemic Agents; Inosine; Insulin; Ischemic Preconditioning; | 2014 |
Protective effect of CDP-choline on ischemia-reperfusion-induced myocardial tissue injury in rats.
Topics: Animals; Apoptosis; Arginine; Blood Pressure; Cytidine Diphosphate Choline; Homocysteine; Lactic Aci | 2014 |
Ischemic preconditioning reduces apoptosis in open heart surgery.
Topics: Animals; Apoptosis; Biomarkers; Cardiac Surgical Procedures; Caspase 3; Ischemic Preconditioning, My | 2014 |
Is warm or cold Calafiore blood cardioplegia better? Hemodynamic, metabolic, and electron microscopic differences.
Topics: Animals; Cardioplegic Solutions; Cold Temperature; Energy Metabolism; Heart Arrest, Induced; Hemodyn | 2014 |
Pharmacological postconditioning with lactic acid and hydrogen rich saline alleviates myocardial reperfusion injury in rats.
Topics: Animals; Apoptosis; Caspase 8; Disease Models, Animal; Female; Hydrogen; Ischemic Postconditioning; | 2015 |
L-Glycyl-L-glutamine provides the isolated and perfused young and middle-aged rat heart protection against ischaemia-reperfusion injury.
Topics: Age Factors; Animals; Dipeptides; Isolated Heart Preparation; Lactic Acid; Lipid Peroxidation; Male; | 2015 |
3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Disease Models, Animal; Electron Transport Comple | 2015 |
Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening.
Topics: Animals; bcl-2-Associated X Protein; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Cytochromes | 2016 |
Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion.
Topics: Administration, Cutaneous; Animals; Cell Line; Disease Models, Animal; Female; Fibroblast Growth Fac | 2016 |
Nanoparticle-Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia-Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial
Topics: Animals; bcl-2-Associated X Protein; Biocompatible Materials; Cell Survival; Cytochromes c; Drug Car | 2016 |
Absence of reperfusion-induced arrhythmia in patients with ST-segment elevation myocardial infarction treated using postconditioning with lactate-enriched blood.
Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Ischemic Postconditioning; Lactic Acid; Male; Myocardial | 2016 |
A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model.
Topics: Anesthesia; Animals; Blood Pressure; Cardiotonic Agents; Cell Death; Cells, Cultured; Consciousness; | 2016 |
Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts.
Topics: Adenine Nucleotides; Animals; Coronary Vessels; Endothelium, Vascular; Free Radical Scavengers; Glyc | 2008 |
Carnitine worsens both injury and recovery of contractile function after transient ischemia in perfused rat heart.
Topics: Animals; Carnitine; Glucose; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocard | 2008 |
Post-conditioning preserves glycolytic ATP during early reperfusion: a survival mechanism for the reperfused heart.
Topics: Adenosine Triphosphate; Animals; Cytosol; Glucose; Glucose Transporter Type 4; Glycolysis; Heart; He | 2008 |
Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.
Topics: Animals; Antithrombins; Capillary Permeability; Coronary Vessels; Edema, Cardiac; Endothelial Cells; | 2009 |
Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.
Topics: Aged; Anaerobic Threshold; Cardiac Output; Cardiopulmonary Bypass; Carnitine; Coronary Artery Diseas | 2009 |
Levosimendan cardioprotection in acutely beta-1 adrenergic receptor blocked open chest pigs.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Clinical Protocols; Female; Glucose; Glyce | 2010 |
Comet assay in evaluating DNA damage associated with ischaemia-reperfusion injury in patients undergoing coronary surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Comet Assay; Coronary Artery Bypass; DNA Damage | 2009 |
Off-pump coronary surgery causes immediate release of myocardial damage markers.
Topics: Aged; Biomarkers; Coronary Artery Bypass, Off-Pump; Creatine Kinase, MB Form; Female; Glutathione; H | 2009 |
Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Topics: Acute Disease; Animals; Basic Helix-Loop-Helix Transcription Factors; Coronary Circulation; Dioxygen | 2010 |
Metabolic monitoring of postischemic myocardium during intermittent warm-blood cardioplegic administration.
Topics: Adult; Aged; Blood Glucose; Cardioplegic Solutions; Coronary Artery Bypass; Elective Surgical Proced | 2010 |
Post-conditioning with cyclosporine A fails to reduce the infarct size in an in vivo porcine model.
Topics: Animals; Biomarkers; Coronary Circulation; Cyclosporine; Hemodynamics; Immunosuppressive Agents; Lac | 2010 |
Pharmacological preconditioning with L-carnitine: relevance to myocardial hemodynamic function and glycogen and lactate content.
Topics: Adenosine Triphosphate; Animals; Carnitine; Glycogen; Hemodynamics; Ischemic Preconditioning, Myocar | 2010 |
Early reperfusion with warm, polarizing adenosine-lidocaine cardioplegia improves functional recovery after 6 hours of cold static storage.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Blood Pressure; Cardiac Output; Cardioplegic Solu | 2011 |
Sustained release of VEGF through PLGA microparticles improves vasculogenesis and tissue remodeling in an acute myocardial ischemia-reperfusion model.
Topics: Animals; Capillaries; Coronary Vessels; Delayed-Action Preparations; Disease Models, Animal; Drug Ca | 2010 |
Severe, short-term food restriction improves cardiac function following ischemia/reperfusion in perfused rat hearts.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Caloric Restriction; Creatine Kinase; D | 2010 |
Exogenous carbon monoxide does not affect cell membrane energy availability assessed by sarcolemmal calcium fluxes during myocardial ischaemia-reperfusion in the pig.
Topics: Animals; Calcium; Carbon Monoxide; Cell Membrane; Coronary Occlusion; Energy Metabolism; Glucose; Is | 2011 |
Substrate selection in hearts subjected to ischemia/reperfusion: role of cardioplegic solutions and gender.
Topics: Amino Acids; Animals; Buffers; Caprylates; Cardioplegic Solutions; Citric Acid Cycle; Disaccharides; | 2011 |
Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Cyclic AMP; Energy Metabolism; Feeding Beha | 2011 |
Exercise-induced cardioprotection is mediated by a bloodborne, transferable factor.
Topics: Adolescent; Adult; Animals; Blood Transfusion; Exercise; Hemodynamics; Humans; In Vitro Techniques; | 2012 |
Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients.
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Hemodynamics; Humans; Ische | 2012 |
Effects of fatty acids on cardioprotection by pre-ischaemic inhibition of the malate-aspartate shuttle.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Fatty Acids; Glucose; Heart; Hemody | 2012 |
Cardioprotective effects of ozone oxidative preconditioning in an in vivo model of ischemia/reperfusion injury in rats.
Topics: Adenine Nucleotides; Animals; Cardiotonic Agents; Creatine Kinase, MB Form; Glutathione; Heart; Hear | 2012 |
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hy | 2013 |
dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Apoptosis; Blood Glucose; Blo | 2002 |
Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance.
Topics: Acclimatization; Animals; Carbon Isotopes; Glucose; Glycogen; Glycolysis; Hot Temperature; Hypothyro | 2002 |
Effects of fasting and hypoxic preconditioning on the hypoxic-reoxygenated ventricular strips of the rat heart.
Topics: Acyl Coenzyme A; Analysis of Variance; Animals; Carnitine; Fasting; Heart Ventricles; Hypoxia; Ische | 2002 |
Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Blood Transfusion, Autologous; Energy Metabolism; G | 2003 |
Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia.
Topics: Animals; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In Vitro Techniques; Lactic Acid | 2003 |
The dual effects of nitric oxide synthase inhibitors on ischemia-reperfusion injury in rat hearts.
Topics: Adenine Nucleotides; Animals; Creatine; Creatine Kinase; Enzyme Inhibitors; Glucose; Glycogen; Heart | 2003 |
Evaluation of cellular energetics by the pasteur effect in intact cardiomyoblasts and isolated perfused hearts.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Cell Line; Energy Metabolism; In Vitro Techniques; Lact | 2004 |
Effects of trimetazidine on myocardial preconditioning in anesthetized rats.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbachol; Coronary Vessels; Creatine Kin | 2004 |
Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury: analysis by mechanical work and energetics.
Topics: Animals; Blood Pressure; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cardiotonic Agent | 2005 |
Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats.
Topics: Animals; Carbon Isotopes; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids; Glucose; In Vit | 2005 |
Trimetazidine protects isolated rat hearts against ischemia-reperfusion injury in an experimental timing-dependent manner.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Drug Administration Schedule; In Vitro Techniqu | 2005 |
Effects of ischaemia-mimetic factors on isolated rat ventricular myocytes.
Topics: Acidosis; Animals; Glucose; Heart Ventricles; Hypoxia; In Vitro Techniques; Lactic Acid; Male; Myoca | 2005 |
Antioxidants and ecto-5'-nucleotidase are not involved in the training-induced cardioprotection against ischaemia-reperfusion injury.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Antioxidants; Biomarkers; Heat-Shock Proteins; HSP | 2005 |
Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Antidotes; Blood Pressure; Catechols; Deferoxamine; Dogs; Heart Ra | 2005 |
Microdialysis separately monitors myocardial interstitial myoglobin during ischemia and reperfusion.
Topics: Animals; Blood Pressure; Glycerol; Heart Rate; Lactic Acid; Male; Microdialysis; Myocardial Ischemia | 2005 |
Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Coronary Circulation; Glucose; Glycer | 2006 |
Expression and activity of the glutamate transporter EAAT2 in cardiac hypertrophy: implications for ischaemia reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Cardiac Output; Cardiomegaly; Cardiotonic Agents; Excitatory Amino | 2006 |
Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs.
Topics: Action Potentials; Animals; Arteries; Blood Pressure; Brain Death; Heart Rate; Heart Ventricles; Hem | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Ischemic Preconditioning, Myocardial; Lactic Acid; | 2006 |
[Coronary sinus lactate levels and insulin in coronary artery bypass surgery].
Topics: Coronary Artery Bypass; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Myocardial Reperfusion In | 2006 |
High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery.
Topics: Animals; Blood Glucose; Body Weight; Dietary Sucrose; Glycolysis; Hyperinsulinism; In Vitro Techniqu | 2007 |
Levosimendan cardioprotection reduces the metabolic response during temporary regional coronary occlusion in an open chest pig model.
Topics: Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Glucose; Hydrazones; Infusions, I | 2007 |
Unveiling gender differences in demand ischemia: a study in a rat model of genetic hypertension.
Topics: Animals; Coronary Circulation; Diastole; Disease Models, Animal; Disease Susceptibility; Female; Hyp | 2007 |
Application of NMR-based metabonomics in the investigation of myocardial ischemia-reperfusion, ischemic preconditioning and antioxidant intervention in rabbits.
Topics: Acetates; Alanine; Animals; Antioxidants; Blood Glucose; Discriminant Analysis; Indoles; Ischemic Pr | 2007 |
Inhibition of glycogen synthase kinase-3beta improves tolerance to ischemia in hypertrophied hearts.
Topics: Animals; Body Weight; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycolysis; Hyper | 2007 |
ICVTS on-line discussion A. Further testing is warranted to detect more subtle degrees...
Topics: Anaerobic Threshold; Animals; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Diseas | 2007 |
Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats.
Topics: Adiponectin; Animals; bcl-X Protein; Cardiovascular Agents; Coronary Vessels; Diabetes Mellitus, Exp | 2007 |
Protection of ischaemic-reperfused rat heart by dimethylamiloride is associated with inhibition of mitochondrial permeability transition.
Topics: Amiloride; Animals; Cardiovascular Agents; Cell Survival; Cyclosporine; Female; Glycolysis; In Vitro | 2008 |
Effects of endotoxin on the guinea pig heart response to ischemia reperfusion injury.
Topics: Animals; Blood Flow Velocity; Endotoxins; Guinea Pigs; Lactates; Lactic Acid; Male; Myocardial Reper | 1995 |
The influence of lactate, pyruvate and glucose as exogenous substrates on free radical defense mechanisms in isolated rat hearts during ischaemia and reperfusion.
Topics: Animals; Antioxidants; Catalase; Free Radicals; Glucose; Glutathione; Glutathione Peroxidase; Glutat | 1995 |
Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischaemia-reperfusion injury.
Topics: Animals; Arginine; Glycogen; Heart; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusi | 1995 |
Taurine protects the heart from neutrophil-induced reperfusion injury.
Topics: Animals; Antioxidants; Coronary Vessels; Glutathione; Guinea Pigs; Heart; Lactates; Lactic Acid; Lum | 1995 |
Preconditioning with dobutamine in the isolated rat heart.
Topics: Animals; Dobutamine; Drug Interactions; Heart; Heart Rate; Lactates; Lactic Acid; Male; Myocardial C | 1995 |
A study on dilazep: I. Mechanism of anti-ischemic action of dilazep is not coronary vasodilation but decreased cardiac mechanical function in the isolated, working rat heart.
Topics: Animals; Arachidonic Acid; Coronary Circulation; Coronary Vessels; Dilazep; Fatty Acids, Nonesterifi | 1995 |
A study on dilazep: II. Dilazep attenuates lysophosphatidylcholine-induced mechanical and metabolic derangements in the isolated, working rat heart.
Topics: Animals; Blood Pressure; Dilazep; Fatty Acids, Nonesterified; Heart; Heart Rate; In Vitro Techniques | 1995 |
Captopril cardioplegia on myocardial protection in the hypertrophied rat hearts.
Topics: Animals; Captopril; Coronary Circulation; Creatine Kinase; Heart Arrest, Induced; Hypertrophy, Left | 1994 |
In vitro administration of ergothioneine failed to protect isolated ischaemic and reperfused rabbit heart.
Topics: Adenine Nucleotides; Animals; Creatine Kinase; Ergothioneine; Glutathione; Glutathione Disulfide; In | 1995 |
Interrupted warm blood cardioplegia for coronary artery bypass grafting.
Topics: Adult; Aged; Cardiac Output; Coronary Artery Bypass; Creatine Kinase; Energy Metabolism; Female; Hea | 1995 |
Preconditioning with a single short episode of global ischemia in the isolated working rat heart: effect on structure, mechanical function, and energy metabolism for various durations of sustained global ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Energy Metabolism; Glycogen; Heart; Heart Arrest; In | 1995 |
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; | 1995 |
Preischaemic as well as postischaemic application of a calcium antagonist affords cardioprotection in the isolated guinea pig heart.
Topics: Animals; Coronary Circulation; Gallopamil; Glutathione; Guinea Pigs; Heart; Lactates; Lactic Acid; L | 1995 |
Heat shock protein (HSP 72) expression in patients undergoing cardiac operations.
Topics: Adolescent; Adult; Aged; Biopsy; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child, | 1995 |
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfu | 1995 |
Protection from reperfusion-induced arrhythmias by polyethylene glycol 600.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Disease Mod | 1993 |
Role of aspirin in modulating myocardial ischemic reperfusion injury.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Aspirin; Blood Pressure; Creatinine; Disease | 1994 |
Pentostatin-augmented interstitial adenosine prevents postcardioplegia injury in damaged hearts.
Topics: Adenosine; Animals; Creatine Kinase; Dogs; Heart Arrest, Induced; Hypoxanthine; Hypoxanthines; Inosi | 1994 |
Heat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts.
Topics: Anaerobiosis; Animals; Blotting, Northern; Creatine Kinase; Deoxyglucose; Gene Expression; HSP70 Hea | 1994 |
Decreasing myocardial pH reflects ischemia during continuous warm retrograde cardioplegic arrest.
Topics: Adenosine Triphosphate; Animals; Cardioplegic Solutions; Dogs; Heart Arrest, Induced; Hydrogen-Ion C | 1994 |
Ischemic dysfunction and impaired recovery in hypertensive hypertrophied hearts is associated with exaggerated intracellular sodium accumulation.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Hydrogen-Ion Concentration; Hypertension; Lactates; L | 1994 |
Ischaemic episodes of less than 5 minutes produce preconditioning but not stunning in the isolated rat heart.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Conditioning, Psychological; Coronary Circulation; Energy | 1994 |
[The cardioprotective effect of alpha-tocopherol and pantenol in a model of experimental ischemia-reperfusion of the isolated heart].
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Lactates; Lactic Acid; Lipid Peroxidation; Mal | 1994 |
The relative importance of myocardial energy metabolism compared with ischemic contracture in the determination of ischemic injury in isolated perfused rabbit hearts.
Topics: Animals; Creatine Kinase; Diacetyl; Energy Metabolism; Glucose; Glycogen; Lactates; Lactic Acid; Myo | 1994 |
Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia.
Topics: Adenosine; Animals; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Inosine; Lactate | 1994 |
Effect of angiotensin converting enzyme inhibition with quinaprilat on the ischaemic and reperfused myocardium.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Creat | 1994 |
Muscarinic receptor stimulation by carbachol improves functional recovery in isolated, blood perfused rabbit heart.
Topics: Adenosine Triphosphate; Animals; Atropine; Blood Pressure; Carbachol; Cardiac Pacing, Artificial; Co | 1993 |
Lack of change in MnSOD during ischemia/reperfusion of isolated rat heart.
Topics: Analysis of Variance; Animals; Citrate (si)-Synthase; Enzyme Activation; In Vitro Techniques; L-Lact | 1993 |
Fluorocarbon simulation of myocardial ischaemia and reperfusion: studies of relationships between force and intracellular calcium.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Ferrets; Fluorocarbons; Hypoxia; Intracellular Fluid | 1993 |
Hypoxic preconditioning attenuates stunning caused by repeated coronary artery occlusions in dog heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Hypoxia; Lact | 1993 |
The influence of the time period between preconditioning ischemia and prolonged ischemia on myocardial protection.
Topics: Adenosine Triphosphate; Animals; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Repe | 1993 |
Effect of prostaglandins I2 (prostacyclin) and F2 alpha on function, energy metabolism, and calcium uptake in ischaemic/reperfused hearts.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium; Dinoprost; Energy Metabolism; Epoprostenol | 1993 |
Effect of ischemic preconditioning on mitochondrial oxidative phosphorylation and high energy phosphates in rat hearts.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anaerobiosis; Animals; Creatine; Creatine Kinase; | 1996 |
A protective role of nitric oxide in isolated ischaemic/reperfused rat heart.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Heart; Lactates; Lactic Acid; Male; Myocardial I | 1995 |
Dichloroacetate reduces plasma lactate levels but does not reduce infarct size in rabbit myocardium.
Topics: Animals; Blood Glucose; Dichloroacetic Acid; Enzyme Activation; Hemodynamics; Lactic Acid; Myocardia | 1996 |
Beneficial effects of felodipine on myocardial and coronary function during low-flow ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relat | 1996 |
Dietary fish oil prevents reperfusion Ins(1,4,5)P3 release in rat heart: possible antiarrhythmic mechanism.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Dietary Fats, Unsaturated; Fish Oils; Inosito | 1996 |
Is warm retrograde blood cardioplegia better than cold for myocardial protection?
Topics: Adenosine Triphosphate; Animals; Blood; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Heart | 1997 |
Glycogen depletion contributes to ischemic preconditioning in the rat heart in vivo.
Topics: Animals; Blood Glucose; Coronary Disease; Glycogen; Hemodynamics; Ischemic Preconditioning, Myocardi | 1996 |
Effect of ischaemia and reperfusion on the intracellular concentration of taurine and glutamine in the hearts of patients undergoing coronary artery surgery.
Topics: Adenosine Triphosphate; Aged; Bicarbonates; Biomarkers; Blood; Calcium Chloride; Cardioplegic Soluti | 1997 |
Effect of desferrioxamine cardioplegia on ischemia-reperfusion injury in isolated rat heart.
Topics: Animals; Deferoxamine; Diastole; Heart Arrest, Induced; Lactic Acid; Male; Microscopy, Electron; Myo | 1997 |
Implication of myocardial lactate metabolism during coronary artery bypass grafting.
Topics: Blood Pressure; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Disease; Female; Humans; La | 1997 |
Donor blood perfusion improves myocardial recovery after heart transplantation.
Topics: Animals; Blood; Blood Pressure; Cardioplegic Solutions; Cost-Benefit Analysis; Cryopreservation; Fem | 1997 |
Lack of any additional benefit in combining aspirin with iloprost in a canine model of myocardial reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Aspirin; Blood Pressure; Cyclooxygenase Inhib | 1997 |
Protective effect of the angiotensin-converting enzyme inhibitor captopril on postischemic myocardial damage in perfused rat heart.
Topics: Adenine Nucleotides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ani | 1997 |
[Safety limit of our myocardial protection method, and possibility of glutamate enriched asanguineous secondary cardioplegia].
Topics: Animals; Cardioplegic Solutions; Dogs; Energy Metabolism; Heart Arrest, Induced; Lactic Acid; Myocar | 1987 |
Preconditioning human cardiomyocytes and endothelial cells.
Topics: Cell Hypoxia; Cells, Cultured; Endothelium, Vascular; Humans; Ischemic Preconditioning, Myocardial; | 1998 |
Does glycogen depletion play an important role in ischemic preconditioning?
Topics: Animals; Glycogen; Hemodynamics; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lactic A | 1997 |
Low concentrations of adenosine receptor blocker decrease protection by hypoxic preconditioning in ischemic rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Creatine Kinase; Hypoxia; In Vitro Techniques; Ischemic | 1998 |
Carbohydrates and purines in underperfused hearts, protected by ischemic preconditioning.
Topics: Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Glucose; Glycogen; In Vitro Techniques; Is | 1998 |
Regulation of pyruvate dehydrogenase activity and glucose metabolism in post-ischaemic myocardium.
Topics: Animals; Dichloroacetic Acid; Dogs; Glucose; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusio | 1998 |
Hypothermia increases the threshold for ischemic preconditioning.
Topics: Animals; Body Temperature; Coronary Circulation; Disease Models, Animal; Glycogen; Hypothermia, Indu | 1998 |
Insulin stimulates pyruvate dehydrogenase and protects human ventricular cardiomyocytes from simulated ischemia.
Topics: Adenine Nucleotides; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; La | 1998 |
Ionic and metabolic imbalance as potential factors of ischemia reperfusion injury.
Topics: Acetylcarnitine; Animals; Dichloroacetic Acid; Disease Models, Animal; Energy Metabolism; Fatty Acid | 1998 |
[Intraoperative and postoperative microdialysis measurement of the human heart--feasibility and initial results].
Topics: Aged; Blood Glucose; Coronary Artery Bypass; Energy Metabolism; Feasibility Studies; Female; Glutath | 1998 |
Influence of an early adrenergic blockade on thrombotic infarct size and myocardial metabolism.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Fe | 1998 |
Effect of endogenous nitric oxide on energy metabolism of rat heart mitochondria during ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Enzyme Inhibitors; Lactic Acid; Male; Mitochondr | 1999 |
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate.
Topics: Adenine Nucleotides; Animals; Capillary Permeability; Deoxyglucose; Hydrogen-Ion Concentration; In V | 1999 |
Efficacy of contraction uncoupling by 2,3-butanedione monoxime during initial reperfusion versus cardioplegic arrest for protection of isolated hearts.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Circulation; Diacetyl; Gui | 1999 |
Myocardial substrate uptake and oxidation during and after routine cardiac surgery.
Topics: Aged; Arteries; Blood Glucose; Carbon Dioxide; Coronary Artery Bypass; Coronary Disease; Energy Meta | 1999 |
Levosimendan: effects of a calcium sensitizer on function and arrhythmias and cyclic nucleotide levels during ischemia/reperfusion in the Langendorff-perfused guinea pig heart.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Agoni | 1999 |
A model of low-flow ischemia and reperfusion in single, beating adult cardiomyocytes.
Topics: Animals; Calcium; Cell Survival; Coronary Circulation; Electric Stimulation; Hydrogen-Ion Concentrat | 1999 |
Pretreatment with PKC activator protects cardiomyocytes against reoxygenation-induced hypercontracture independently of Ca2+ overload.
Topics: Analysis of Variance; Animals; Calcium; Cells, Cultured; Cytosol; Diglycerides; Enzyme Activation; H | 1999 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relati | 1999 |
Myocardial self-preservative effect of heat shock protein 70 on an immature lamb heart.
Topics: Animals; Animals, Newborn; Coronary Circulation; Endothelium, Vascular; HSP70 Heat-Shock Proteins; I | 1999 |
Glucose metabolism in reperfused myocardium measured by [2-18F] 2-fluorodeoxyglucose and PET.
Topics: Animals; Dogs; Fluorodeoxyglucose F18; Glucose; Glycolysis; Heart; Image Processing, Computer-Assist | 2000 |
Effects of supplemental L-arginine during warm blood cardioplegia.
Topics: Animals; Arginine; Blood; Cardioplegic Solutions; Creatine Kinase; E-Selectin; Enzyme Inhibitors; He | 2000 |
Cardioprotective effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor, on cardiac dysfunction induced by ischemia/reperfusion in isolated rat hearts.
Topics: Animals; Carnitine; Enzyme Inhibitors; gamma-Butyrobetaine Dioxygenase; Heart Function Tests; Hemody | 2000 |
Effects of Hot shot on recovery after hypothermic ischemia in neonatal lamb heart.
Topics: Animals; Animals, Newborn; Blood; Cardioplegic Solutions; Coronary Circulation; Coronary Vessels; En | 2001 |
Ventricular arrhythmias following coronary artery occlusion in rats: is the diabetic heart less or more sensitive to ischaemia?
Topics: Animals; Blood Glucose; Coronary Disease; Diabetes Mellitus, Experimental; Glycogen; In Vitro Techni | 2001 |
An ultrafiltration catheter for monitoring of venous lactate and glucose around myocardial ischemia.
Topics: Animals; Biosensing Techniques; Blood Glucose; Catheterization; Coronary Vessels; Lactic Acid; Monit | 2001 |
Ischemic-reperfused isolated working mouse hearts: membrane damage and type IIA phospholipase A2.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cardiac Output; Cell Membrane; Fatty Acids; Fe | 2001 |
Lactate release during reperfusion predicts low cardiac output syndrome after coronary bypass surgery.
Topics: Aged; Cardiac Output, Low; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Female | 2001 |
Toward a better understanding of the metabolic effects of ischemic preconditioning in humans.
Topics: Animals; Coronary Artery Bypass; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardi | 2001 |
Postischemic mechanoenergetic inefficiency is related to contractile dysfunction and not altered metabolism.
Topics: Animals; Blood Glucose; Blood Pressure; Carbon Radioisotopes; Energy Metabolism; Fatty Acids; Glucos | 2001 |
Very low dose of the Na(+)/Ca(2+) exchange inhibitor, KB-R7943, protects ischemic reperfused aged Fischer 344 rat hearts: considerable strain difference in the sensitivity to KB-R7943.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Electrocardiography; Immunoblotting; Lactic Acid; M | 2001 |
Discrepant outcome between myocardial energy-related metabolites and infarct size limitation during retroperfusion of the coronary sinus.
Topics: Animals; Coronary Circulation; Energy Metabolism; Guanosine; Jugular Veins; Lactic Acid; Microdialys | 2001 |
Intraoperative metabolic monitoring of the heart: I. Clinical assessment of coronary sinus metabolites.
Topics: Energy Metabolism; Heart Arrest, Induced; Heart Diseases; Humans; Intraoperative Complications; Lact | 2001 |
Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury.
Topics: Animals; Cardiotonic Agents; Carrier Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2002 |
Monitoring of porcine myocardial ischemia and reperfusion by intravasal microdialysis.
Topics: Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Female; Glutamic Acid; Glycerol; Hemodyn | 2002 |
Chronic hypoxia: a model for cyanotic congenital heart defects.
Topics: Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Chronic Disease; Cyanosis; Disease Models, | 2002 |
Generation of singlet oxygen and hydroxyl radical from sodium chlorite and lactic acid.
Topics: Alkenes; Benzofurans; Chlorides; Cholesterol; Chromatography, High Pressure Liquid; Deuterium; Free | 1992 |
Alterations in substrate utilization in the reperfused myocardium: a direct analysis by 13C NMR.
Topics: Acetates; Animals; Glutamates; Glutamic Acid; In Vitro Techniques; Lactates; Lactic Acid; Magnetic R | 1992 |
Protective effect of selenium in cardiac ischemia and reperfusion.
Topics: Adenine Nucleotides; Animals; Creatine Kinase; Diet; Free Radical Scavengers; Glutathione Peroxidase | 1992 |
The effects of L-arginine mono(2-mercaptoethanesulfonate) on the ischemic and reperfused heart.
Topics: Adenosine Triphosphate; Animals; Arginine; Creatine Kinase; Free Radicals; Glutathione; Lactates; La | 1992 |
Effects of duration of ischaemia during preconditioning on mechanical function, enzyme release and energy production in the isolated working rat heart.
Topics: Adenine Nucleotides; Animals; Creatine Kinase; Energy Metabolism; Glycogen; Heart; In Vitro Techniqu | 1992 |
Recruitment of myocardial work and metabolism in regionally stunned porcine myocardium.
Topics: Animals; Coronary Circulation; Dobutamine; Female; Heart; Hemodynamics; Lactates; Lactic Acid; Male; | 1992 |
Intracoronary administration of saralasin: effects on cardiac arrhythmias induced by ischaemia and reperfusion in the anaesthetised dog.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vessels; Creatine Kinase; Dogs; Female; Heart; Lactates; Lac | 1992 |
Cardioprotective effect of pindolol in ischemic-reperfused isolated rat hearts.
Topics: Adenine Nucleotides; Animals; Fatty Acids, Nonesterified; Heart; Lactates; Lactic Acid; Male; Myocar | 1992 |
Effects of catecholamine stimulation on myocardial hibernation.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Glycogen; Lactates; Lactic Acid; Myocardial C | 1992 |
Postischemic free radical production in the venous blood of the regionally ischemic swine heart. Effect of deferoxamine.
Topics: Alcohols; Animals; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radical | 1991 |
Not all neonatal hearts are equally protected from ischemic damage during hypothermia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Heart Arrest, Induced; Hypothermia, Induced; Lact | 1991 |
The effect of lidocaine on myocardial ischemia with asanguinous reperfusion. An in vitro study.
Topics: Adenine Nucleotides; Animals; Coronary Circulation; Heart Arrest, Induced; In Vitro Techniques; Lact | 1991 |
Studies of myocardial protection in the immature heart. III. Models of ischemic and hypoxic/ischemic injury in the immature puppy heart.
Topics: Adenosine Triphosphate; Amino Acids, Dicarboxylic; Animals; Carboxylic Acids; Coronary Circulation; | 1991 |
[The reversal of the protective effects of intermittent perfusion on ischemic myocardium by hypoxic, no-substrates, zero-K+ perfusate].
Topics: Adenosine Triphosphate; Animals; Calcium; Energy Metabolism; In Vitro Techniques; Lactates; Lactic A | 1991 |
Effect of graded reductions of coronary pressure and flow on myocardial metabolism and performance: a model of "hibernating" myocardium.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Lactates; Lactic Acid; | 1991 |
Antioxidant protection against damage during cardiac ischemia and reperfusion: effect of dimercapto-propanol.
Topics: Animals; Creatine Kinase; Dimercaprol; Free Radical Scavengers; Glutathione; Lactates; Lactic Acid; | 1990 |
Tolerance of the hypertrophic heart to ischemia. Studies in compensated and failing dog hearts with pressure overload hypertrophy.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Dogs; Heart Arrest, Induced; He | 1990 |
The protective action of pyruvate on recovery of ischemic rat heart: comparison with other oxidizable substrates.
Topics: Acetates; Animals; Coronary Disease; Energy Metabolism; Glucose; Heart; Insulin; Lactates; Lactic Ac | 1990 |
Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium; Coronary Disease; Diltiazem; Fatty Acids, | 1990 |
Lactate does not enhance anoxia/reoxygenation damage in adult rat cardiac myocytes.
Topics: Animals; Cell Survival; Glucose; Hydrogen-Ion Concentration; In Vitro Techniques; Lactates; Lactic A | 1990 |
[Energy reserves and the extent of heart injury in ischemia and reperfusion during single and repeated administration of cardioplegic solutions].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cardioplegic Solutions; Energy Metabolism; Gly | 1989 |
Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3.
Topics: Animals; Antioxidants; Catechin; Chemical Phenomena; Chemistry; Coronary Circulation; Deferiprone; I | 1989 |
[Relation between myocardial perfusion, myocardial necrosis and residual glucose metabolism as a vitality parameter in the post-ischemic myocardium following coronary reperfusion].
Topics: Aged; Animals; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Coronary Disease; Coronary | 1989 |
Myocardial free-radical injury after cardioplegia.
Topics: Free Radicals; Heart Arrest, Induced; Humans; Lactates; Lactic Acid; Lipid Peroxidation; Middle Aged | 1989 |