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lactic acid and Injuries, Multiple

lactic acid has been researched along with Injuries, Multiple in 36 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"In cases of Polytrauma induced sepsis or septic shock, the level started to increase within first 72 hours after traumatic injury, pick concentration was achieved within first 25 days high from the beginning and dynamically increases within first 25 days, the tendency of gradual decrease was seen after 30 days."5.48THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS. ( Kanashvili, B; Ratiani, L; Saganelidze, K, 2018)
"Bosutinib as an adjunct therapy to a balanced transfusion strategy reduced resuscitation volume, improved shock reversal, and reduced vascular leak and organ injury in a rat polytrauma model."4.02Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model. ( Aman, J; Botros, L; Hollmann, MW; Juffermans, NP; Kers, J; Kleinveld, DJB; Maas, MAW, 2021)
" Lactic acidosis and poor cardiac performance, as evidenced by low cardiac index (CI) with normal filling pressures, were seen in all cases of MSOF and RC, as well as in all deaths."3.70The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma. ( Blow, O; Butler, K; Claridge, JA; Magliore, L; Young, JS, 1999)
"After severe multiple injuries (first hit) a two-phase immunological response with early hyperinflammation followed by immunosuppression can be observed."2.49[Pathophysiology of multiple trauma : intensive care medicine and timing of treatment]. ( Lehnert, M; Lustenberger, T; Marzi, I; Relja, B; Wutzler, S, 2013)
"In a rat model of multiple injuries and hemorrhagic shock, early administration of EVs significantly reduced the elevation of lactate and creatinine and did not significantly enhance coagulopathy in rats with acute traumatic coagulopathy."1.62Extracellular vesicles derived from cardiosphere-derived cells as a potential antishock therapeutic. ( Atai, NA; Bynum, JA; Cap, AP; Chance, TC; Garcia-Marcano, J; Gould, SJ; Keesee, JD; Liu, B; Marban, LS; Moseley, JJ; Peck, KA; R-Borlado, L; Rathbone, CR; Salgado, CL; Wu, X, 2021)
"In cases of Polytrauma induced sepsis or septic shock, the level started to increase within first 72 hours after traumatic injury, pick concentration was achieved within first 25 days high from the beginning and dynamically increases within first 25 days, the tendency of gradual decrease was seen after 30 days."1.48THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS. ( Kanashvili, B; Ratiani, L; Saganelidze, K, 2018)
"Trauma-induced coagulopathy (TIC) in multiple trauma patients is a potentially lethal complication."1.43Clinical presentation and blood gas analysis of multiple trauma patients for prediction of standard coagulation parameters at emergency department arrival. ( Hilbert-Carius, P; Hofmann, GO; Lefering, R; Struck, MF; Stuttmann, R, 2016)
"The lactic acid was measured at the beginning and at 24 hours of the trauma and associating it with the patient morbidity and mortality."1.38[Measurement of lactic acid in multiple injury patients and its usefulness as a predictor of multiorgan failure and mortality]. ( Gómez Díaz, C; Llaquet Bayo, H; Luna Aufroy, A; Montmany Vioque, S; Navarro Soto, S; Rebasa Cladera, P, 2012)
"Infection and sepsis have a close relationship with bacterial translocation."1.33[Clinical study on bacterial translocation in severe multiple trauma patients]. ( Deng, Q; Li, JY; Li, ZL; Lin, HY; Lu, LR; Lü, Y; Qiao, Z, 2006)
"The damage of gut barrier in multiple trauma appears to be more severe than that in one-site trauma, thereby promoting gut-derived endotoxemia and bacterial translocation and contributing to the development of endogenous infection."1.31Gut barrier function damage following multiple firearm injuries in a porcine model. ( Li, Z; Lu, L; Yang, X; Yao, Y; Yu, Y, 2001)
"Eighty patients with multiple trauma were studied (514 samples) during their intensive care unit courses (Injury Severity Score 27."1.31Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response. ( Rixen, D; Siegel, JH, 2000)
"In trauma patients, hypothermia is a frequent event."1.30Adenosine-triphosphate in trauma-related and elective hypothermia. ( Hildebrandt, F; Seekamp, A; Tscherne, H; van Griensven, M; Wahlers, T, 1999)
"In trauma patients hypothermia is a frequent event."1.30[Role of adenosine triphosphate (ATP) in trauma-induced and elective hypothermia]. ( Grotz, M; Hildebrand, F; Seekamp, A; Tscherne, H; van Griensven, M, 1999)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's5 (13.89)18.2507
2000's13 (36.11)29.6817
2010's12 (33.33)24.3611
2020's5 (13.89)2.80

Authors

AuthorsStudies
Özakın, E1
Özcan Yazlamaz, N1
Baloğlu Kaya, F1
Çanakçı, ME1
Bilgin, M1
Shehu, A1
Kalbas, Y1
Teuben, MPJ1
Pape, HC1
Pfeifer, R1
Kleinveld, DJB1
Botros, L1
Maas, MAW1
Kers, J1
Aman, J1
Hollmann, MW1
Juffermans, NP1
Chance, TC1
Wu, X1
Keesee, JD1
Garcia-Marcano, J1
Salgado, CL1
Liu, B1
Moseley, JJ1
Peck, KA1
R-Borlado, L1
Atai, NA1
Gould, SJ1
Marban, LS1
Cap, AP1
Rathbone, CR1
Bynum, JA1
Qi, J1
Bao, L1
Yang, P1
Chen, D1
Londoño, J1
Niño, C1
Díaz, J1
Morales, C1
León, J1
Bernal, E1
Vargas, C1
Mejía, L1
Hincapié, C1
Ascuntar, J1
León, A1
Jaimes, F1
Kanashvili, B1
Saganelidze, K1
Ratiani, L1
Kireyeva, EA1
Stogov, MV1
Karasev, AG1
Wutzler, S1
Lustenberger, T1
Relja, B1
Lehnert, M1
Marzi, I1
Qian, A1
Zhang, M1
Zhao, G1
Hilbert-Carius, P1
Hofmann, GO1
Lefering, R1
Stuttmann, R1
Struck, MF1
Saad, S1
Mohamed, N1
Moghazy, A1
Ellabban, G1
El-Kamash, S1
Dekker, SE1
de Vries, HM1
Lubbers, WD1
van de Ven, PM1
Toor, EJ1
Bloemers, FW1
Geeraedts, LMG1
Schober, P1
Boer, C1
Ahmed, AI1
Soliman, RA1
Samir, S1
Honore, PM1
Joannes-Boyau, O1
Boer, W1
Mackenzie, CF1
Morrison, C1
Jaberi, M1
Genuit, T1
Katamuluwa, S1
Rodriguez, A1
Zehtabchi, S2
Liu, T1
Morshed, S1
Corrales, LA1
Lin, K1
Miclau, T1
Montmany Vioque, S1
Navarro Soto, S1
Rebasa Cladera, P1
Luna Aufroy, A1
Gómez Díaz, C1
Llaquet Bayo, H1
Grey, B1
Rodseth, RN1
Muckart, DJ1
Li, Z1
Yang, X1
Lu, L1
Yu, Y1
Yao, Y1
Kaplan, LJ2
Kellum, JA1
Gumanenko, EK1
Nemchenko, NS1
Goncharov, AV1
Pashkovskiĭ, EV1
Sinert, R1
Goldman, M1
Kapitanyan, R1
Ballas, J1
Qiao, Z1
Li, ZL1
Li, JY2
Lin, HY1
Deng, Q1
Lu, LR1
Lü, Y1
Chytra, I1
Pradl, R1
Bosman, R1
Pelnár, P1
Kasal, E1
Zidková, A1
Wahl, W1
Pelletier, K1
Schmidtmann, S1
Junginger, T1
Seekamp, A2
van Griensven, M2
Hildebrandt, F1
Wahlers, T1
Tscherne, H2
Blow, O1
Magliore, L1
Claridge, JA2
Butler, K1
Young, JS2
Hildebrand, F1
Grotz, M1
Oehler, R1
Weingartmann, G1
Manhart, N1
Salzer, U1
Meissner, M1
Schlegel, W1
Spittler, A1
Bergmann, M1
Kandioler, D1
Oismüller, C1
Struse, HM1
Roth, E1
Crowl, AC1
Kahler, DM1
Chrzanowski, DS1
Pomphrey, M1
Rixen, D1
Siegel, JH1
McPartland, K1
Santora, TA1
Trooskin, SZ1
Sunderland, PM1
Heilbrun, MP1
Brandl, M1
Pscheidl, E1
Amann, W1
Barjasic, A1
Pasch, T1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units[NCT02652364]112 participants (Actual)Observational2015-10-31Completed
Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974]196 participants (Anticipated)Interventional2015-12-31Recruiting
Bedside Resources to Gauge Intravascular Volume Status in Hypovolemic Infants in the Operating Room[NCT03915587]23 participants (Actual)Interventional2019-04-08Completed
A Multi-center Randomized Comparison of a Minimally-invasive Cardiovascular Hemodynamic Optimization (MiCHO) Protocol Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock Patients Presenting to the Emergency Department[NCT00535821]Phase 45 participants (Actual)Interventional2007-06-30Terminated (stopped due to slow enrollement unavailable technology)
Early Lactate-Directed Therapy on the ICU: A Randomized Controlled Trial[NCT00270673]Phase 3350 participants (Anticipated)Interventional2006-02-28Completed
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)[NCT01128413]22 participants (Actual)Interventional2010-07-31Terminated (stopped due to lack of resources)
The Effect of Pre- and Postoperative Supplemental Enteral Nutrition in High-Risk Patients Undergoing Elective Cardiac Surgery. A Prospective Double Blind Study.[NCT00247793]0 participants Interventional1996-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Utility of Compensatory Reserve Index (CRI) Which Ranges From 0-1 in Order to Predict Fluid Responders From Non-responders

"Using a delta peak aortic velocity threshold of 10% (measured from CardioQ-EDM) before and after a bolus to define fluid responders (=/>10%) from non-responders (<10%), we will determine the performance of pre-bolus CRI reading which is an index between 0 and 1 (0=poor reserve and 1=excellent reserve) in order to predict fluid responders from non-responders. Measurements will be recorded three times with one minute between measurements and then averaged.~Vital signs analyzed included heart rate, systolic blood pressure, mean arterial pressure, shock index (heart rate/systolic blood pressure), pulse pressure variability, and end-tidal carbon dioxide level. Infants were also monitored with a Compensatory Reserve Index (CRI) monitor, which provides a continuous, individual-specific, beat-to-beat estimate of central volume status, from normovolemia (CRI=1) to decompensation (CRI=0). Each variable's performance was compared using area under the receiver operator curves (AUC)." (NCT03915587)
Timeframe: Through study completion (3-4 hours)

Interventionunits on a scale (Mean)
Fluid Challenge Responders0.06
Fluid Challenge Non-responders0.05

Mortality

In-hospital mortality (NCT00535821)
Timeframe: hospital

Interventionparticipants (Number)
MiCHO0
EGDT0

Lactate Clearance

The median lactate clearance from time zero to within 6 hours of the ED stay. (NCT01128413)
Timeframe: The median lactate clearance within 6 hours of the ED stay.

Interventionpercent lactate clearance (Median)
Fluid Optimization (FO)54
Routine Care (RC)56

Reviews

2 reviews available for lactic acid and Injuries, Multiple

ArticleYear
Definition of occult hypoperfusion in trauma: A systematic literature review.
    Injury, 2023, Volume: 54, Issue:3

    Topics: Hemodynamics; Humans; Injury Severity Score; Lactic Acid; Multiple Trauma; Vital Signs

2023
[Pathophysiology of multiple trauma : intensive care medicine and timing of treatment].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2013, Volume: 84, Issue:9

    Topics: Blood Coagulation; Cause of Death; Combined Modality Therapy; Cooperative Behavior; Critical Care; D

2013

Trials

2 trials available for lactic acid and Injuries, Multiple

ArticleYear
Association of Clinical Hypoperfusion Variables With Lactate Clearance and Hospital Mortality.
    Shock (Augusta, Ga.), 2018, Volume: 50, Issue:3

    Topics: Adult; Aged; Female; Hospital Mortality; Humans; Hyperlactatemia; Infections; Lactic Acid; Male; Mid

2018
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
    Critical care (London, England), 2007, Volume: 11, Issue:1

    Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal

2007

Other Studies

32 other studies available for lactic acid and Injuries, Multiple

ArticleYear
Lactate and base deficit combination score for predicting blood transfusion need in blunt multi-trauma patients.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:5

    Topics: Adult; Blood Transfusion; Female; Glasgow Coma Scale; Humans; Lactic Acid; Male; Multiple Trauma; Sh

2022
Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model.
    British journal of anaesthesia, 2021, Volume: 126, Issue:5

    Topics: Aniline Compounds; Animals; Blood Transfusion; Disease Models, Animal; Endothelium, Vascular; Lactic

2021
Extracellular vesicles derived from cardiosphere-derived cells as a potential antishock therapeutic.
    The journal of trauma and acute care surgery, 2021, 08-01, Volume: 91, Issue:2S Suppl 2

    Topics: Animals; Blood Glucose; Creatinine; Disease Models, Animal; Extracellular Vesicles; Flow Cytometry;

2021
Comparison of base excess, lactate and pH predicting 72-h mortality of multiple trauma.
    BMC emergency medicine, 2021, 07-07, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Female; Hospital Mortality; Humans; Hydrogen-Ion Concentration; Lact

2021
THE ROLE OF PROCALCITONIN AND BLOOD LACTIC ACID VALUES IN PROGNOSIS OF SEPSIS AND SEPTIC SHOCK IN POLYTRAUMA PATIENTS.
    Georgian medical news, 2018, Issue:279

    Topics: Biomarkers; C-Reactive Protein; Humans; Lactic Acid; Multiple Trauma; Procalcitonin; Prognosis; Seps

2018
[The laboratory biochemical markers of severity of trauma in acute period after multiple fractures of bones of extremities].
    Klinicheskaia laboratornaia diagnostika, 2016, Volume: 61, Issue:6

    Topics: Acid Phosphatase; Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Creatine Kin

2016
Dynamic detection of N-terminal pro-B-type natriuretic peptide helps to predict the outcome of patients with major trauma.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2015, Volume: 41, Issue:1

    Topics: Adult; Aged; Biomarkers; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Middle Aged; Multiple

2015
Clinical presentation and blood gas analysis of multiple trauma patients for prediction of standard coagulation parameters at emergency department arrival.
    Der Anaesthesist, 2016, Volume: 65, Issue:4

    Topics: Accidents; Adult; Aged; Anticoagulants; Blood Coagulation; Blood Gas Analysis; Emergency Medical Ser

2016
Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2016, Volume: 22, Issue:1

    Topics: Adult; APACHE; Biomarkers; Blood Glucose; Cross-Sectional Studies; Egypt; Emergency Service, Hospita

2016
Lactate clearance metrics are not superior to initial lactate in predicting mortality in trauma.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2017, Volume: 43, Issue:6

    Topics: Adult; Biomarkers; Brain Injuries, Traumatic; Female; Glasgow Coma Scale; Humans; Lactic Acid; Male;

2017
Cell Free DNA and Procalcitonin as Early Markers of Complications in ICU Patients with Multiple Trauma and Major Surgery.
    Clinical laboratory, 2016, Dec-01, Volume: 62, Issue:12

    Topics: Adult; Area Under Curve; Biomarkers; C-Reactive Protein; Calcitonin; Cell-Free Nucleic Acids; DNA; E

2016
Strong ion gap and outcome after cardiac arrest: another nail in the coffin of traditional acid-base quantification.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Analysis of Variance; Biomechanical Phenomena;

2009
Management of hemorrhagic shock when blood is not an option.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:7

    Topics: Blood Substitutes; Hemoglobins; Humans; Jehovah's Witnesses; Lactic Acid; Male; Multiple Trauma; Sho

2008
Effect of hypoperfusion and the protein C pathway on the early coagulopathy after traumatic brain injury.
    The Journal of trauma, 2008, Volume: 65, Issue:6

    Topics: Adult; Blood Coagulation Disorders; Brain Injuries; Brain Ischemia; Hemoperitoneum; Humans; Lactic A

2008
Femoral nailing during serum bicarbonate-defined hypo-perfusion predicts pulmonary organ dysfunction in multi-system trauma patients.
    Injury, 2011, Volume: 42, Issue:7

    Topics: Adult; Anion Transport Proteins; Antiporters; Cohort Studies; Female; Femoral Fractures; Fracture Fi

2011
[Measurement of lactic acid in multiple injury patients and its usefulness as a predictor of multiorgan failure and mortality].
    Cirugia espanola, 2012, Volume: 90, Issue:2

    Topics: Adult; Humans; Lactic Acid; Middle Aged; Multiple Organ Failure; Multiple Trauma; Predictive Value o

2012
Early fracture stabilisation in the presence of subclinical hypoperfusion.
    Injury, 2013, Volume: 44, Issue:2

    Topics: Adult; Arterial Pressure; Cell Hypoxia; Female; Femoral Fractures; Fracture Fixation, Internal; Frac

2013
Gut barrier function damage following multiple firearm injuries in a porcine model.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2001, Volume: 16, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Animals; Bacterial Translocation; Endotoxemia; Endotoxins; Femora

2001
Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury.
    Critical care medicine, 2004, Volume: 32, Issue:5

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Age Distribution; Analysis of Variance; Biomechan

2004
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:6

    Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag

2004
Diagnostic performance of serial haematocrit measurements in identifying major injury in adult trauma patients.
    Injury, 2006, Volume: 37, Issue:1

    Topics: Adult; Female; Hematocrit; Hemorrhage; Humans; Infusions, Intravenous; Injury Severity Score; Lactic

2006
[Clinical study on bacterial translocation in severe multiple trauma patients].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2006, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Bacterial Translocation; DNA, Bacterial; Female; Humans; Intestines; Lactic Acid;

2006
[Experiences with various scores in evaluating the prognosis of postoperative intensive care patients].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1996, Volume: 67, Issue:7

    Topics: Abdomen; APACHE; Critical Care; Humans; Lactic Acid; Length of Stay; Mathematical Computing; Multipl

1996
Adenosine-triphosphate in trauma-related and elective hypothermia.
    The Journal of trauma, 1999, Volume: 47, Issue:4

    Topics: Adenosine Triphosphate; Adolescent; Adult; Body Temperature; Coronary Artery Bypass; Elective Surgic

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
    The Journal of trauma, 1999, Volume: 47, Issue:5

    Topics: Acidosis, Lactic; Adult; Critical Care; Female; Hemodynamics; Humans; Injury Severity Score; Ischemi

1999
[Role of adenosine triphosphate (ATP) in trauma-induced and elective hypothermia].
    Zentralblatt fur Chirurgie, 1999, Volume: 124, Issue:11

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Body Temperature Regulation; Coronary Artery Bypass

1999
Polytrauma induces increased expression of pyruvate kinase in neutrophils.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Adult; Aged; Cells, Cultured; Enzyme Induction; Female; Glycolysis; Humans; Lactic Acid; Male; Middl

2000
Occult hypoperfusion is associated with increased morbidity in patients undergoing early femur fracture fixation.
    The Journal of trauma, 2000, Volume: 48, Issue:2

    Topics: Adult; Cell Hypoxia; Clinical Protocols; Femoral Fractures; Fracture Fixation, Intramedullary; Human

2000
Metabolic correlates of oxygen debt predict posttrauma early acute respiratory distress syndrome and the related cytokine response.
    The Journal of trauma, 2000, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Cytokines; Enzyme-Linked Immunosorbent

2000
Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients.
    The Journal of trauma, 2001, Volume: 50, Issue:4

    Topics: Algorithms; Blood Gas Analysis; Blood Pressure; Cardiac Output; Critical Care; Decision Trees; Diast

2001
Estimating energy expenditure in traumatic brain injury: comparison of indirect calorimetry with predictive formulas.
    Neurosurgery, 1992, Volume: 31, Issue:2

    Topics: Adult; Blood Glucose; Blood Urea Nitrogen; Brain Injuries; Calorimetry, Indirect; Energy Intake; Ene

1992
Biochemical and hormonal parameters in patients with multiple trauma.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Biomarkers; Biopterins; Humans; Lactates; Lactic Acid; Multiple Trauma; Neopterin; Retrospective Stu

1989