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lactic acid and Infections, Prosthesis-Related

lactic acid has been researched along with Infections, Prosthesis-Related in 19 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The levels of inflammatory markers in serum [white blood cells, C-reactive protein (CRPS)] and synovial fluid [synovial fluid white blood cell count (SFWBC), percentage of polymorphonuclear cells (%PMN), lactic acid, lactate dehydrogenase (LDH), glucose, total protein] of patients suffering from septic arthritis (n = 114), PJI (n = 67), non-infectious joint diseases (n = 495) and arthralgia after total joint arthroplasty (n = 43) were determined."3.81Diagnostic potential of inflammatory markers in septic arthritis and periprosthetic joint infections: a clinical study with 719 patients. ( Lenski, M; Scherer, MA, 2015)
" Systemic antibiotics often do not reach "dead-space" hematomas where bacteria harbor after surgery, whereas local, controlled release gentamicin prophylaxis through PLGA microspheres showed favorable pharmacokinetics data to achieve local bactericidal concentrations for up to 7 days after surgery."3.75Reduction of postoperative spinal implant infection using gentamicin microspheres. ( Becker, E; Gelb, D; Ludwig, SC; Poelstra, KA; Stall, AC, 2009)
"D-lactic acid is a specific marker produced almost exclusively by bacterial species; thus, the appearance of this marker in synovial fluid may indicate periprosthetic joint infection (PJI)."1.91What is the Accuracy of a Rapid Strip Test That Detects D-lactic Acid in Synovial Fluid for the Diagnosis of Periprosthetic Joint Infections? ( Grajek, A; Grzelecki, D; Kowalczewski, J; Walczak, P, 2023)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (31.58)29.6817
2010's7 (36.84)24.3611
2020's6 (31.58)2.80

Authors

AuthorsStudies
Li, Z1
Li, C1
Wang, G1
Shi, L1
Li, T1
Fan, X1
Xu, X1
Wang, P1
Gao, F1
Sun, W1
Svoboda, M1
Gallo, J1
Zapletalová, J1
Prošková, J1
Juráňová, J1
Lovečková, Y1
Chen, Y1
Wang, H1
Chen, X1
Ma, H1
Zheng, J1
Cao, L1
Grzelecki, D1
Grajek, A1
Walczak, P1
Kowalczewski, J1
Schlatterer, D1
Karbysheva, S2
Yermak, K2
Grigoricheva, L1
Renz, N2
Perka, C2
Trampuz, A2
Roth, J1
Soleman, J1
Kozyrev, DA1
Jabang, JN1
Stein, M1
Grisaru-Soen, G1
Benvenisti, H1
Sadot, E1
Friedman, S1
Ayalon, I1
Goldiner, I1
Stark, M1
Hassoun, E1
Constantini, S1
Pitarresi, G1
Palumbo, FS1
Calascibetta, F1
Fiorica, C1
Di Stefano, M1
Giammona, G1
Gilchrist, SE1
Lange, D1
Letchford, K1
Bach, H1
Fazli, L1
Burt, HM1
Neut, D1
Dijkstra, RJ1
Thompson, JI1
Kavanagh, C1
van der Mei, HC1
Busscher, HJ1
Lenski, M1
Scherer, MA1
Stall, AC1
Becker, E1
Ludwig, SC1
Gelb, D1
Poelstra, KA1
Cai, W1
Wu, J1
Xi, C1
Meyerhoff, ME1
Su, SH1
Chao, RY1
Landau, CL1
Nelson, KD1
Timmons, RB1
Meidell, RS1
Eberhart, RC1
Etienne, O1
Picart, C1
Taddei, C1
Haikel, Y2
Dimarcq, JL1
Schaaf, P2
Voegel, JC2
Ogier, JA1
Egles, C1
Schultz, P1
Vautier, D1
Richert, L1
Jessel, N1
Ogier, J1
Debry, C1
Soriano, A1
Miró, O1
Mensa, J1
Aviv, M1
Berdicevsky, I1
Zilberman, M1

Reviews

1 review available for lactic acid and Infections, Prosthesis-Related

ArticleYear
Diagnostic accuracy of synovial fluid D-lactate for periprosthetic joint infection: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2021, Oct-16, Volume: 16, Issue:1

    Topics: Arthritis, Infectious; Biomarkers; Humans; Lactic Acid; Prosthesis-Related Infections; Quality of Li

2021

Other Studies

18 other studies available for lactic acid and Infections, Prosthesis-Related

ArticleYear
[Glucose, Lactate, NGAL and Coefficient of Energy Balance in Synovial Fluid in Patients with Hip and Knee Prosthetic Joint Infection].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2022, Volume: 89, Issue:1

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biomarkers; C-Reactive Protein; Glu

2022
Serum D-lactate, a novel serological biomarker, is promising for the diagnosis of periprosthetic joint infection.
    BMC musculoskeletal disorders, 2022, Mar-26, Volume: 23, Issue:1

    Topics: Arthroplasty, Replacement, Hip; Biomarkers; Blood Sedimentation; C-Reactive Protein; Humans; Lactic

2022
What is the Accuracy of a Rapid Strip Test That Detects D-lactic Acid in Synovial Fluid for the Diagnosis of Periprosthetic Joint Infections?
    Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1

    Topics: Arthritis, Infectious; Biomarkers; Humans; Lactic Acid; Prospective Studies; Prosthesis-Related Infe

2023
CORR Insights®: What is the Accuracy of a Rapid Strip Test That Detects D-lactic Acid in Synovial Fluid for the Diagnosis of Periprosthetic Joint Infections?
    Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1

    Topics: Arthritis, Infectious; Biomarkers; Humans; Joint Prosthesis; Lactic Acid; Prosthesis-Related Infecti

2023
Synovial Fluid d-Lactate-A Novel Pathogen-Specific Biomarker for the Diagnosis of Periprosthetic Joint Infection.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:8

    Topics: Arthroplasty, Replacement, Hip; Biomarkers; C-Reactive Protein; Humans; Lactic Acid; Prosthesis-Rela

2020
Performance of synovial fluid D-lactate for the diagnosis of periprosthetic joint infection: A prospective observational study.
    The Journal of infection, 2019, Volume: 79, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Arthroplasty, Replacement, Hip; Biomarkers; E

2019
Value of Cerebrospinal Fluid Lactate Levels in Diagnosing Shunt Infections in Pediatric Patients.
    World neurosurgery, 2019, Volume: 129

    Topics: Biomarkers; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid

2019
Medicated hydrogels of hyaluronic acid derivatives for use in orthopedic field.
    International journal of pharmaceutics, 2013, Jun-05, Volume: 449, Issue:1-2

    Topics: Anti-Bacterial Agents; Cells, Cultured; Femur; Fibroblasts; Humans; Hyaluronic Acid; Hydrogels; Lact

2013
Fusidic acid and rifampicin co-loaded PLGA nanofibers for the prevention of orthopedic implant associated infections.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Aug-28, Volume: 170, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Arthroplasty, Replacement; Bacterial Infections; Drug Delivery Syste

2013
A biodegradable gentamicin-hydroxyapatite-coating for infection prophylaxis in cementless hip prostheses.
    European cells & materials, 2015, Jan-02, Volume: 29

    Topics: Animals; Anti-Bacterial Agents; Bone Cements; Bone Nails; Coated Materials, Biocompatible; Dogs; Dru

2015
Diagnostic potential of inflammatory markers in septic arthritis and periprosthetic joint infections: a clinical study with 719 patients.
    Infectious diseases (London, England), 2015, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Arthralgia; Arthritis, Infectious; Bio

2015
Reduction of postoperative spinal implant infection using gentamicin microspheres.
    Spine, 2009, Mar-01, Volume: 34, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Bone Nails; Delayed-Action Preparations; Dr

2009
Diazeniumdiolate-doped poly(lactic-co-glycolic acid)-based nitric oxide releasing films as antibiofilm coatings.
    Biomaterials, 2012, Volume: 33, Issue:32

    Topics: Anti-Bacterial Agents; Azo Compounds; Biofilms; Coated Materials, Biocompatible; Escherichia coli; E

2012
Expandable bioresorbable endovascular stent. I. Fabrication and properties.
    Annals of biomedical engineering, 2003, Volume: 31, Issue:6

    Topics: Absorbable Implants; Animals; Blood Pressure; Blood Vessel Prosthesis; Coated Materials, Biocompatib

2003
Multilayer polyelectrolyte films functionalized by insertion of defensin: a new approach to protection of implants from bacterial colonization.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10

    Topics: Adsorption; Anti-Infective Agents; Bacterial Adhesion; Defensins; Electrolytes; Escherichia coli; La

2004
Polyelectrolyte multilayers functionalized by a synthetic analogue of an anti-inflammatory peptide, alpha-MSH, for coating a tracheal prosthesis.
    Biomaterials, 2005, Volume: 26, Issue:15

    Topics: alpha-MSH; Animals; Anti-Inflammatory Agents; Coated Materials, Biocompatible; Drug Implants; Electr

2005
Mitochondrial toxicity associated with linezolid.
    The New England journal of medicine, 2005, Nov-24, Volume: 353, Issue:21

    Topics: Acetamides; Adult; Aged; Anti-Infective Agents; Asthenia; Brain Abscess; Electron Transport Complex

2005
Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants.
    Journal of biomedical materials research. Part A, 2007, Volume: 83, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biofilms; Colony Count, Microbial; Gentamicin

2007