lactic acid has been researched along with Infection in 41 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Excerpt | Relevance | Reference |
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"Dobutamine was used to increase cardiac output, thereby directly varying TO2 under conditions of constant O2 demand." | 5.29 | Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome. ( Dantzker, DR; Gutierrez, G; Krachman, SL; Lodato, RF; Morice, R, 1994) |
"We evaluated the ability of four biomarkers (C-Reactive protein (CRP), lactate, mid-regional proadrenomedullin (MR-proADM) and procalcitonin (PCT)) to detect each kind of organ failure considered in the SOFA in 213 patients with infection, sepsis or septic shock, by using multivariate regression analysis and calculation of the area under the receiver operating curve (AUROC)." | 3.96 | MR- proADM to detect specific types of organ failure in infection. ( Aldecoa, C; Almansa, R; Andaluz-Ojeda, D; Andrés, C; Bermejo-Martin, JF; Calvo, D; Cicuendez, R; Esteban-Velasco, MC; Martín, S; Martin-Fernandez, M; Muñoz-Bellvís, L; Nogales, L; Ríos-Llorente, A; Sanchez-Barrado, E; Vaquero-Roncero, LM, 2020) |
"To determine whether the levels of oxygen consumption (VO2) required to relieve an existing oxygen debt are variable, increases in VO2 produced by increases in oxygen delivery (DO2) were evaluated longitudinally in septic patients with lactic acidosis and related to changes in lactate levels." | 3.68 | Lack of a relationship between induced changes in oxygen consumption and changes in lactate levels. ( Silverman, HJ, 1991) |
"These data indicate that lactic acidosis does not entirely account for the metabolic acidosis during severe sepsis." | 3.68 | Unaccounted for anion in metabolic acidosis during severe sepsis in humans. ( Astiz, ME; Mecher, C; Rackow, EC; Weil, MH, 1991) |
"Validation of the host-mRNA infection severity classifier IMX-SEV-2." | 1.72 | Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department. ( Bauer, W; Bergström, WH; Buturovic, L; Diehl-Wiesenecker, E; Galtung, N; Kappert, K; Lehmann, D; Liesenfeld, O; Luethy, R; Markmann, N; Mayhew, M; Somasundaram, R; Sweeney, TE; Tauber, R; Wacker, J, 2022) |
"Among them, 23." | 1.51 | Blood lactate measurement within the emergency department: A two-year retrospective analysis. ( Contenti, J; Ferrari, P; Lemoel, F; Levraut, J; Occelli, C, 2019) |
"Disease progression was identified using a composite endpoint of 28-day mortality, ICU admission and hospitalisation > 10 days." | 1.51 | The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study. ( Amin, D; Beau, N; Bernardini, S; Bloos, F; Brandi, A; Callejo, CC; Chan, L; Claessens, YE; Cortes, N; Del Castillo, JG; Dryden, M; Hausfater, P; Kutz, A; Legramante, JM; Limper, M; Macchi, MA; Melander, O; Minieri, M; Mueller, B; Patka, P; Rood, PPM; Rosenqvist, M; Saeed, K; Schuetz, P; van der Does, Y; van Gorp, ECM; White, G; Wilson, DC; Yañez, MC, 2019) |
"Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis." | 1.43 | Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). ( Angus, DC; Brunkhorst, FM; Deutschman, CS; Escobar, GJ; Iwashyna, TJ; Kahn, JM; Liu, VX; Rea, TD; Rubenfeld, G; Scherag, A; Seymour, CW; Shankar-Hari, M; Singer, M, 2016) |
"Ten cases of infection were reported during the study with higher prevalence in F-OR (70%) than that in AF (20%) and CTL (10%)." | 1.40 | Functional overreaching: the key to peak performance during the taper? ( Aubry, A; Coutts, AJ; Hausswirth, C; LE Meur, Y; Louis, J, 2014) |
"Inclusion criteria were suspected infection evidenced by administration of antibiotics in the ED and measurement of whole blood lactate in the ED." | 1.38 | Prognostic value of incremental lactate elevations in emergency department patients with suspected infection. ( Jones, AE; Kline, JA; Puskarich, MA; Summers, RL, 2012) |
"The presence or absence of infection was determined by review of International Classification of Diseases Ninth Revision (ICD-9) admission diagnosis codes." | 1.36 | Emergency department lactate is associated with mortality in older adults admitted with and without infections. ( del Portal, DA; Dorsey, PJ; Gaieski, DF; Goyal, M; Mikkelsen, ME; Pines, JM; Shofer, F; Synnestvedt, M; Weiner, MG, 2010) |
"Dobutamine was used to increase cardiac output, thereby directly varying TO2 under conditions of constant O2 demand." | 1.29 | Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome. ( Dantzker, DR; Gutierrez, G; Krachman, SL; Lodato, RF; Morice, R, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (4.88) | 18.7374 |
1990's | 11 (26.83) | 18.2507 |
2000's | 8 (19.51) | 29.6817 |
2010's | 14 (34.15) | 24.3611 |
2020's | 6 (14.63) | 2.80 |
Authors | Studies |
---|---|
Galtung, N | 1 |
Diehl-Wiesenecker, E | 1 |
Lehmann, D | 1 |
Markmann, N | 1 |
Bergström, WH | 1 |
Wacker, J | 1 |
Liesenfeld, O | 2 |
Mayhew, M | 1 |
Buturovic, L | 1 |
Luethy, R | 1 |
Sweeney, TE | 2 |
Tauber, R | 1 |
Kappert, K | 1 |
Somasundaram, R | 1 |
Bauer, W | 1 |
Kostaki, A | 1 |
Wacker, JW | 1 |
Safarika, A | 1 |
Solomonidi, N | 1 |
Katsaros, K | 1 |
Giannikopoulos, G | 1 |
Koutelidakis, IM | 1 |
Hogan, CA | 1 |
Uhle, F | 1 |
Giamarellos-Bourboulis, EJ | 1 |
Andrés, C | 1 |
Andaluz-Ojeda, D | 1 |
Cicuendez, R | 1 |
Nogales, L | 1 |
Martín, S | 1 |
Martin-Fernandez, M | 1 |
Almansa, R | 1 |
Calvo, D | 1 |
Esteban-Velasco, MC | 1 |
Vaquero-Roncero, LM | 1 |
Ríos-Llorente, A | 1 |
Sanchez-Barrado, E | 1 |
Muñoz-Bellvís, L | 1 |
Aldecoa, C | 1 |
Bermejo-Martin, JF | 1 |
Martín-Rodríguez, F | 1 |
López-Izquierdo, R | 1 |
Medina-Lozano, E | 1 |
Ortega Rabbione, G | 1 |
Del Pozo Vegas, C | 1 |
Carbajosa Rodríguez, V | 1 |
Castro Villamor, MÁ | 1 |
Sánchez-Soberon, I | 1 |
Sanz-García, A | 1 |
Guyther, J | 1 |
Cantwell, L | 1 |
Manoharan, I | 1 |
Prasad, PD | 1 |
Thangaraju, M | 1 |
Manicassamy, S | 1 |
Londoño, J | 1 |
Niño, C | 1 |
Díaz, J | 1 |
Morales, C | 1 |
León, J | 1 |
Bernal, E | 1 |
Vargas, C | 1 |
Mejía, L | 1 |
Hincapié, C | 1 |
Ascuntar, J | 1 |
León, A | 1 |
Jaimes, F | 1 |
Contenti, J | 1 |
Occelli, C | 1 |
Lemoel, F | 1 |
Ferrari, P | 1 |
Levraut, J | 1 |
Ramirez-Zuniga, I | 1 |
Rubin, JE | 1 |
Swigon, D | 1 |
Clermont, G | 1 |
Saeed, K | 1 |
Wilson, DC | 1 |
Bloos, F | 1 |
Schuetz, P | 1 |
van der Does, Y | 1 |
Melander, O | 1 |
Hausfater, P | 1 |
Legramante, JM | 1 |
Claessens, YE | 1 |
Amin, D | 1 |
Rosenqvist, M | 1 |
White, G | 1 |
Mueller, B | 1 |
Limper, M | 1 |
Callejo, CC | 1 |
Brandi, A | 1 |
Macchi, MA | 1 |
Cortes, N | 1 |
Kutz, A | 1 |
Patka, P | 1 |
Yañez, MC | 2 |
Bernardini, S | 1 |
Beau, N | 1 |
Dryden, M | 1 |
van Gorp, ECM | 1 |
Minieri, M | 1 |
Chan, L | 1 |
Rood, PPM | 1 |
Del Castillo, JG | 1 |
Salido Mota, M | 1 |
Fuentes Ferrer, M | 1 |
Julián-Jiménez, A | 1 |
Piñera, P | 1 |
Llopis, F | 1 |
Gamazo Del Rio, J | 1 |
Martínez Ortiz de Zarate, M | 1 |
Estella, A | 1 |
Martín-Sánchez, FJ | 1 |
González Del Castillo, J | 1 |
Shu, W | 1 |
Wan, J | 1 |
Chen, J | 1 |
He, W | 1 |
Zhu, Y | 1 |
Lu, N | 1 |
Xia, L | 1 |
Puskarich, MA | 2 |
Illich, BM | 1 |
Jones, AE | 2 |
Aubry, A | 1 |
Hausswirth, C | 1 |
Louis, J | 1 |
Coutts, AJ | 1 |
LE Meur, Y | 1 |
Seymour, CW | 1 |
Liu, VX | 1 |
Iwashyna, TJ | 1 |
Brunkhorst, FM | 1 |
Rea, TD | 1 |
Scherag, A | 1 |
Rubenfeld, G | 1 |
Kahn, JM | 1 |
Shankar-Hari, M | 1 |
Singer, M | 1 |
Deutschman, CS | 1 |
Escobar, GJ | 1 |
Angus, DC | 1 |
del Portal, DA | 1 |
Shofer, F | 1 |
Mikkelsen, ME | 1 |
Dorsey, PJ | 1 |
Gaieski, DF | 2 |
Goyal, M | 2 |
Synnestvedt, M | 1 |
Weiner, MG | 1 |
Pines, JM | 1 |
Shaw, LB | 1 |
Schwartz, IB | 1 |
Alves, RL | 1 |
Aragão e Silva, AL | 1 |
Kraychete, NC | 1 |
Campos, GO | 1 |
Martins, Mde J | 1 |
Módolo, NS | 1 |
Kline, JA | 1 |
Summers, RL | 1 |
Dankiewicz, J | 1 |
Linder, A | 1 |
Annborn, M | 1 |
Rundgren, M | 1 |
Friberg, H | 1 |
Martinez, A | 1 |
Chiolero, R | 1 |
Bollman, M | 1 |
Revelly, JP | 1 |
Berger, M | 1 |
Cayeux, C | 1 |
Tappy, L | 1 |
Mortier, S | 1 |
Faict, D | 1 |
Lameire, NH | 1 |
De Vriese, AS | 1 |
Shapiro, NI | 1 |
Howell, MD | 1 |
Talmor, D | 1 |
Nathanson, LA | 1 |
Lisbon, A | 1 |
Wolfe, RE | 1 |
Weiss, JW | 1 |
Chytra, I | 1 |
Pradl, R | 1 |
Bosman, R | 1 |
Pelnár, P | 1 |
Kasal, E | 1 |
Zidková, A | 1 |
Mercier, D | 1 |
Jones, J | 1 |
Leu, HS | 1 |
Huang, CH | 1 |
Cheng, DL | 1 |
Krachman, SL | 1 |
Lodato, RF | 1 |
Morice, R | 1 |
Gutierrez, G | 1 |
Dantzker, DR | 1 |
Molteni, KH | 1 |
Groeneveld, AB | 1 |
Vermeij, CG | 1 |
Nauta, JJ | 1 |
Thijs, LG | 1 |
Harada, M | 1 |
Hisaoka, S | 1 |
Mori, K | 1 |
Yoneda, K | 1 |
Noda, S | 1 |
Nishitani, H | 1 |
Brown, EM | 1 |
Teupe, C | 1 |
Meffert, R | 1 |
Winckler, S | 1 |
Ritzerfeld, W | 1 |
Törmälä, P | 1 |
Brug, E | 1 |
Silverman, HJ | 1 |
Angerås, U | 1 |
Hall-Angerås, M | 1 |
Wagner, KR | 1 |
James, H | 1 |
Hasselgren, PO | 2 |
Fischer, JE | 2 |
Arnold, J | 1 |
Shipley, KA | 1 |
Scott, NA | 1 |
Little, RA | 1 |
Irving, MH | 1 |
Weg, JG | 1 |
Mecher, C | 1 |
Rackow, EC | 1 |
Astiz, ME | 1 |
Weil, MH | 1 |
Hotchkiss, RS | 1 |
Song, SK | 1 |
Ling, CS | 1 |
Ackerman, JJ | 1 |
Karl, IE | 1 |
Warner, BW | 1 |
Hummel, RP | 1 |
James, JH | 1 |
Pedersen, P | 1 |
Schirmer, WJ | 1 |
Schirmer, JM | 1 |
Townsend, MC | 1 |
Fry, DE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Sepsis Prognosis and Diagnosis in the Emergency Department Using a Host Response Classifier (SPEED) UK - a Multi-Centre Observational Study[NCT05639504] | 0 participants (Actual) | Observational | 2022-12-31 | Withdrawn (stopped due to Study never started, change in company focus on US) | |||
Pneumonia Direct Pilot[NCT06181669] | 250 participants (Anticipated) | Observational | 2024-01-31 | Not yet recruiting | |||
ADAPTED: Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department[NCT03992794] | 684 participants (Actual) | Observational [Patient Registry] | 2018-03-15 | Completed | |||
Comment Diminuer Les hémocultures Inutiles : Construction et Validation d'un Score prédictif de positivité Des hémocultures en réanimation.[NCT05686577] | 2,400 participants (Anticipated) | Observational | 2022-11-22 | Recruiting | |||
Early Efferon LPS Hemoperfusion Through Hypercrosslinked Styrene-divinylbenzene Copolymer With Immobilized LPS-selective Ligand for Treatment of Patients With Septic Shock[NCT04884854] | 9 participants (Actual) | Observational | 2019-09-13 | Completed | |||
The Correlation of Regional Cerebral Oxygen Saturation(rScO2) Variation in Passive Leg Raising (PLR) With Neurological Outcomes of Sepsis and Septic Shock Patients[NCT03523169] | 120 participants (Actual) | Observational [Patient Registry] | 2016-12-31 | Completed | |||
Evaluation of the PliNOSa® Test as an Aid in the Risk Assessment for the Onset of Sepsis[NCT01371929] | 166 participants (Actual) | Observational | 2013-02-04 | Terminated (stopped due to NIH funding ended prior to full enrollment in the clinical study) | |||
Impact of Intraoperative Goal-directed Blood Pressure Management and Dexmedetomidine on Outcomes of High-risk Patients After Major Abdominal Surgeries: a 2×2 Factorial Randomized Controlled Trial[NCT03933306] | Phase 4 | 496 participants (Actual) | Interventional | 2019-05-20 | Active, not recruiting | ||
La Sepsi Nel Paziente Anziano: Studio Prospettico Sui Pazienti Ricoverati in Ambiente Internistico.[NCT04945889] | 580 participants (Actual) | Observational | 2019-04-01 | Completed | |||
DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study)[NCT04624945] | 150 participants (Anticipated) | Observational | 2020-11-25 | Recruiting | |||
Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965] | 350 participants (Anticipated) | Observational | 2018-08-15 | Active, not recruiting | |||
Contribution of Pre-hospital Blood Lactate Level for Pre-hospital Orientation of Septic Shock[NCT03831685] | 1,000 participants (Anticipated) | Observational | 2018-03-01 | Recruiting | |||
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)[NCT01128413] | 22 participants (Actual) | Interventional | 2010-07-31 | Terminated (stopped due to lack of resources) | |||
Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974] | 196 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
Bedside Resources to Gauge Intravascular Volume Status in Hypovolemic Infants in the Operating Room[NCT03915587] | 23 participants (Actual) | Interventional | 2019-04-08 | Completed | |||
A Multi-center Randomized Comparison of a Minimally-invasive Cardiovascular Hemodynamic Optimization (MiCHO) Protocol Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock Patients Presenting to the Emergency Department[NCT00535821] | Phase 4 | 5 participants (Actual) | Interventional | 2007-06-30 | Terminated (stopped due to slow enrollement unavailable technology) | ||
Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units[NCT02652364] | 112 participants (Actual) | Observational | 2015-10-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The median lactate clearance from time zero to within 6 hours of the ED stay. (NCT01128413)
Timeframe: The median lactate clearance within 6 hours of the ED stay.
Intervention | percent lactate clearance (Median) |
---|---|
Fluid Optimization (FO) | 54 |
Routine Care (RC) | 56 |
"Using a delta peak aortic velocity threshold of 10% (measured from CardioQ-EDM) before and after a bolus to define fluid responders (=/>10%) from non-responders (<10%), we will determine the performance of pre-bolus CRI reading which is an index between 0 and 1 (0=poor reserve and 1=excellent reserve) in order to predict fluid responders from non-responders. Measurements will be recorded three times with one minute between measurements and then averaged.~Vital signs analyzed included heart rate, systolic blood pressure, mean arterial pressure, shock index (heart rate/systolic blood pressure), pulse pressure variability, and end-tidal carbon dioxide level. Infants were also monitored with a Compensatory Reserve Index (CRI) monitor, which provides a continuous, individual-specific, beat-to-beat estimate of central volume status, from normovolemia (CRI=1) to decompensation (CRI=0). Each variable's performance was compared using area under the receiver operator curves (AUC)." (NCT03915587)
Timeframe: Through study completion (3-4 hours)
Intervention | units on a scale (Mean) |
---|---|
Fluid Challenge Responders | 0.06 |
Fluid Challenge Non-responders | 0.05 |
In-hospital mortality (NCT00535821)
Timeframe: hospital
Intervention | participants (Number) |
---|---|
MiCHO | 0 |
EGDT | 0 |
5 reviews available for lactic acid and Infection
Article | Year |
---|---|
Big Tests in Little People.
Topics: Asthma; Biomarkers; Child; Fibrin Fibrinogen Degradation Products; Heart Diseases; Humans; Infection | 2021 |
Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages.
Topics: Animals; Autoimmunity; Cell Cycle Proteins; Dendritic Cells; Humans; Immunomodulation; Infections; I | 2021 |
Prognosis of emergency department patients with suspected infection and intermediate lactate levels: a systematic review.
Topics: Adult; Aged; Biomarkers; Emergency Service, Hospital; Female; Humans; Infections; Lactic Acid; Male; | 2014 |
Infections in neurosurgery: using laboratory data to plan optimal treatment strategies.
Topics: Bacterial Infections; C-Reactive Protein; Clinical Laboratory Techniques; Humans; Infections; Interl | 2002 |
Oxygen transport in adult respiratory distress syndrome and other acute circulatory problems: relationship of oxygen delivery and oxygen consumption.
Topics: Biological Transport; Cardiac Output; Humans; Infections; Lactates; Lactic Acid; Multiple Organ Fail | 1991 |
3 trials available for lactic acid and Infection
Article | Year |
---|---|
Association of Clinical Hypoperfusion Variables With Lactate Clearance and Hospital Mortality.
Topics: Adult; Aged; Female; Hospital Mortality; Humans; Hyperlactatemia; Infections; Lactic Acid; Male; Mid | 2018 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial.
Topics: Adult; Aorta, Thoracic; Blood Pressure; Echocardiography, Doppler; Echocardiography, Transesophageal | 2007 |
Lipid infusion increases oxygen consumption similarly in septic and nonseptic patients.
Topics: Adult; Blood Glucose; Epinephrine; Fat Emulsions, Intravenous; Female; Humans; Hydrocortisone; Infec | 1991 |
33 other studies available for lactic acid and Infection
Article | Year |
---|---|
Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department.
Topics: Biomarkers; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Lactic Acid; Multip | 2022 |
A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS.
Topics: Adult; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Intensive Care Units; La | 2022 |
MR- proADM to detect specific types of organ failure in infection.
Topics: Adrenomedullin; Aged; Aged, 80 and over; Area Under Curve; Blood Coagulation Disorders; C-Reactive P | 2020 |
Accuracy of prehospital point-of-care lactate in early in-hospital mortality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulances; Area Under Curve; Cardiovascular Diseases; E | 2020 |
Blood lactate measurement within the emergency department: A two-year retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Emergency Service, Hospital; Female; France; Hospital Mo | 2019 |
Mathematical modeling of energy consumption in the acute inflammatory response.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Humans; Infections; Inflammation; Lactic Acid; M | 2019 |
The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study.
Topics: Adolescent; Adrenomedullin; Adult; Aged; Aged, 80 and over; Area Under Curve; Biomarkers; C-Reactive | 2019 |
[Comparison of different strategies for short-term death prediction in the infected older patient].
Topics: Aged; Aged, 80 and over; Area Under Curve; Cohort Studies; Comorbidity; Drug Resistance, Bacterial; | 2019 |
Elevated arterial lactate level as an independent risk factor for pancreatic infection in moderately severe acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Female; Humans; Infections; Lactic Acid; Male; Middle Aged; Pancreatitis | 2019 |
Functional overreaching: the key to peak performance during the taper?
Topics: Adult; Affect; Athletic Performance; Bicycling; Fatigue; Humans; Infections; Lactic Acid; Male; Oxyg | 2014 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units; | 2016 |
Emergency department lactate is associated with mortality in older adults admitted with and without infections.
Topics: Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Creatinine; Critical Illness; Emergenc | 2010 |
Enhanced vaccine control of epidemics in adaptive networks.
Topics: Adaptation, Physiological; Disease Outbreaks; Endemic Diseases; Infections; Lactic Acid; Monte Carlo | 2010 |
Intraoperative lactate levels and postoperative complications of pediatric cardiac surgery.
Topics: Adolescent; Blood Gas Analysis; Blood Volume; Cardiac Surgical Procedures; Cardiopulmonary Bypass; C | 2012 |
Prognostic value of incremental lactate elevations in emergency department patients with suspected infection.
Topics: Aged; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Lactic Ac | 2012 |
Heparin-binding protein: an early indicator of critical illness and predictor of outcome in cardiac arrest.
Topics: Aged; Antimicrobial Cationic Peptides; APACHE; Biomarkers; Blood Proteins; Carrier Proteins; Female; | 2013 |
Assessment of adipose tissue metabolism by means of subcutaneous microdialysis in patients with sepsis or circulatory failure.
Topics: Adipose Tissue; Adult; Aged; Blood Glucose; Case-Control Studies; Fatty Acids, Nonesterified; Female | 2003 |
Benefits of switching from a conventional to a low-GDP bicarbonate/lactate-buffered dialysis solution in a rat model.
Topics: Animals; Bicarbonates; Dialysis Solutions; Female; Guanosine Diphosphate; Infections; Lactic Acid; M | 2005 |
Serum lactate as a predictor of mortality in emergency department patients with infection.
Topics: Adult; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Hospitalization; Humans; Inf | 2005 |
Serum lactate as a predictor of mortality in emergency department patients with infection.
Topics: Adult; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Hospitalization; Humans; Inf | 2005 |
Serum lactate as a predictor of mortality in emergency department patients with infection.
Topics: Adult; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Hospitalization; Humans; Inf | 2005 |
Serum lactate as a predictor of mortality in emergency department patients with infection.
Topics: Adult; Cohort Studies; Emergency Service, Hospital; Hospital Mortality; Hospitalization; Humans; Inf | 2005 |
Serum lactate as a predictor of mortality in emergency department patients with infection: does the lactate level tell the whole story?
Topics: Emergency Medicine; Emergency Service, Hospital; Hospital Mortality; Humans; Infections; Lactic Acid | 2005 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Serum lactate as a marker for mortality in patients presenting to the emergency department with infection.
Topics: Adult; Biomarkers; Emergency Service, Hospital; Evidence-Based Medicine; Humans; Infections; Informa | 2007 |
[The diagnostic value of cerebrospinal fluid lactic acid level in central nervous system infection (author's transl)].
Topics: Adolescent; Adult; Aged; Central Nervous System Diseases; Diagnosis, Differential; Evaluation Studie | 1981 |
Effects of dobutamine on oxygen transport and consumption in the adult respiratory distress syndrome.
Topics: Adult; Aged; Blood Gas Analysis; Dobutamine; Dose-Response Relationship, Drug; Female; Hemodynamics; | 1994 |
Blood lactate concentrations and neonatal sepsis.
Topics: Biomarkers; Humans; Infant, Newborn; Infections; Lactates; Lactic Acid | 1993 |
Vasodilating prostaglandin E1 decreases critical oxygen delivery by increasing critical oxygen extraction in anesthetized pigs.
Topics: Alprostadil; Anesthesia; Animals; Cardiac Output; Hemodynamics; Infections; Lactates; Lactic Acid; M | 1993 |
Differences in water diffusion and lactate production in two different types of postinfectious encephalopathy.
Topics: Body Water; Brain Chemistry; Brain Diseases; Child; Echo-Planar Imaging; Encephalomyelitis, Acute Di | 2000 |
Ciprofloxacin-impregnated poly-L-lactic acid drug carrier. New aspects of a resorbable drug delivery system in local antimicrobial treatment of bone infections.
Topics: Biological Assay; Bone Diseases; Ciprofloxacin; Delayed-Action Preparations; Drug Delivery Systems; | 1992 |
Lack of a relationship between induced changes in oxygen consumption and changes in lactate levels.
Topics: Acidosis, Lactic; Blood Transfusion; Dobutamine; Female; Fluid Therapy; Humans; Infections; Lactates | 1991 |
Tissue metabolite levels in different types of skeletal muscle during sepsis.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Energy Metabolism; Hindlimb; Humans; Infections; Lac | 1991 |
Unaccounted for anion in metabolic acidosis during severe sepsis in humans.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Aged, 80 and over; Anions; Blood Proteins; Creatine; F | 1991 |
Sepsis does not alter red blood cell glucose metabolism or Na+ concentration: a 2H-, 23Na-NMR study.
Topics: Animals; Blood Glucose; Deuterium; Erythrocytes; Female; Fluorometry; Infections; Lactates; Lactic A | 1990 |
Effect of catabolic hormone infusion on protein turnover and amino acid uptake in skeletal muscle.
Topics: Amino Acids; Aminobutyrates; Animals; Blood Glucose; Epinephrine; Glucagon; Hormones; Hydrocortisone | 1990 |
Flow redistribution in a hyperdynamic small animal burn: comparison to patterns in sepsis.
Topics: Animals; Burns; Female; Infections; Lactates; Lactic Acid; Liver; Liver Circulation; Muscles; Pyruva | 1987 |