lactic acid has been researched along with Infant, Newborn, Diseases in 17 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4." | 7.66 | Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982) |
| "The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4." | 3.66 | Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Torres Yordán, NC | 1 |
| Lewis, AG | 1 |
| McElrath, TF | 1 |
| Tolan, NV | 1 |
| Greenberg, JA | 1 |
| Y, RB | 1 |
| S, LR | 1 |
| Lewis, LE | 1 |
| Cascant-Vilaplana, MM | 1 |
| Lara-Cantón, I | 1 |
| Núñez-Ramiro, A | 1 |
| Solaz-García, Á | 1 |
| Llorens-Salvador, R | 1 |
| Quintás, G | 1 |
| Kuligowski, J | 1 |
| Vento, M | 1 |
| Polnaszek, B | 1 |
| López, JD | 1 |
| Clark, R | 1 |
| Raghuraman, N | 1 |
| Macones, GA | 2 |
| Cahill, AG | 2 |
| Einikyte, R | 1 |
| Snieckuviene, V | 1 |
| Ramasauskaite, D | 1 |
| Panaviene, J | 1 |
| Paliulyte, V | 1 |
| Opolskiene, G | 1 |
| Kazenaite, E | 1 |
| Chassard, C | 1 |
| de Wouters, T | 1 |
| Lacroix, C | 1 |
| Tuuli, MG | 1 |
| Stout, MJ | 1 |
| Shanks, A | 1 |
| Odibo, AO | 1 |
| Martí Gamboa, S | 1 |
| Pascual Mancho, J | 1 |
| Rodrigo Rodríguez, M | 1 |
| Ruiz Sada, J | 1 |
| Castán Mateo, S | 1 |
| de Boode, WP | 1 |
| ZNAMENACEK, K | 1 |
| PRIBYLOVA, H | 1 |
| García-Cazorla, A | 1 |
| De Lonlay, P | 1 |
| Nassogne, MC | 1 |
| Rustin, P | 1 |
| Touati, G | 1 |
| Saudubray, JM | 1 |
| Wasterlain, CG | 1 |
| Dwyer, BE | 1 |
| Krieger, IE | 1 |
| Nigro, M | 1 |
| Sarnaik, A | 1 |
| Taqi, Q | 1 |
| Swanström, S | 1 |
| Bratteby, LE | 1 |
| Domenech, E | 1 |
| Moya, M | 1 |
| Barroso, F | 1 |
| Rodríguez Luis, JC | 1 |
| González Espinosa, C | 1 |
| Deshpande, SA | 1 |
| Platt, MP | 1 |
| McHattie, JC | 1 |
| Crossan, M | 1 |
| Talukdar, C | 1 |
| Elder, R | 1 |
| Murdock, AI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oxygen for Category II Intrauterine Fetal Resuscitation: A Randomized, Noninferiority Trial[NCT02741284] | 114 participants (Actual) | Interventional | 2016-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Determined by umbilical artery cord gas collected at time of delivery and only in patients with paired (umbilical artery and umbilical vein) cord gases. (NCT02741284)
Timeframe: At delivery
| Intervention | mmol/L (Mean) |
|---|---|
| Room Air | 3.5 |
| Oxygen | 3.4 |
Number of patients with resolution of recurrent variable or recurrent late decelerations within 60 minutes of randomization (NCT02741284)
Timeframe: 60 minutes after randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| No Oxygen | 49 |
| Oxygen | 43 |
As determined by cord gas collection at time of delivery (NCT02741284)
Timeframe: At time of delivery
| Intervention | meq/L (Mean) |
|---|---|
| Room Air | -3.6 |
| Oxygen | -3.6 |
Partial pressure of carbon dioxide as collected on cord gases at time of delivery (NCT02741284)
Timeframe: At time of delivery
| Intervention | mmHg (Mean) |
|---|---|
| Room Air | 55.9 |
| Oxygen | 57.4 |
Determined by umbilical artery cord gas collected at time of delivery and only in patients with paired (umbilical artery and umbilical vein) cord gases. (NCT02741284)
Timeframe: At time of delivery
| Intervention | pH units (Mean) |
|---|---|
| Room Air | 7.26 |
| Oxygen | 7.25 |
Partial pressure of oxygen as collected on cord gases at time of delivery (NCT02741284)
Timeframe: Time of delivery
| Intervention | mm Hg (Mean) |
|---|---|
| Room Air | 19.7 |
| Oxygen | 24.4 |
Delivery via Cesarean section, operative vaginal delivery (forceps or vacuum), or spontaneous vaginal delivery (NCT02741284)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Cesarean delivery | Cesarean delivery for non reassuring fetal status | Operative vaginal delivery | Spontaenous vaginal delivery | |
| Oxygen | 6 | 2 | 1 | 41 |
| Room Air | 2 | 0 | 6 | 43 |
1 review available for lactic acid and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Probiotics tailored to the infant: a window of opportunity.
Topics: Bifidobacterium; Dietary Supplements; Feces; Gastrointestinal Tract; Humans; Infant Formula; Infant, | 2014 |
16 other studies available for lactic acid and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Point-of-care assessment of combined umbilical arterial and venous lactate: A potential screening test for neonatal acidosis.
Topics: Acidosis; Cross-Sectional Studies; Fetal Blood; Humans; Hydrogen-Ion Concentration; Infant, Newborn; | 2022 |
Umbilical Cord Blood Acid-Base Parameters and Lactate as Predictors of Subsequent Meconium Aspiration Syndrome in Neonates.
Topics: Amniotic Fluid; Female; Fetal Blood; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lactic Acid | 2022 |
Longitudinal perturbations of plasma nuclear magnetic resonance profiles in neonatal encephalopathy.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Brain Injuries; Humans; Hypothermia, Induced; Hypoxia-Ischemia, B | 2023 |
Marked variability in intrapartum electronic fetal heart rate patterns: association with neonatal morbidity and abnormal arterial cord gas.
Topics: Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Electrocardiography; Fetal Blood; Fetal Monitoring | 2020 |
The comparison of umbilical cord arterial blood lactate and pH values for predicting short-term neonatal outcomes.
Topics: Apgar Score; Female; Fetal Blood; Humans; Hydrogen-Ion Concentration; Hypoxia; Infant, Newborn; Infa | 2017 |
Umbilical cord arterial lactate compared with pH for predicting neonatal morbidity at term.
Topics: Academic Medical Centers; Apgar Score; Blood Gas Analysis; Cause of Death; Cohort Studies; Female; F | 2014 |
pH, base deficit or lactate. Which is better for predicting neonatal morbidity?
Topics: Blood Gas Analysis; Fetal Blood; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Newbor | 2017 |
Clinical monitoring of systemic hemodynamics in critically ill newborns.
Topics: Acid-Base Equilibrium; Blood Circulation; Blood Pressure; Body Temperature; Critical Illness; Heart | 2010 |
THE SIGNIFICANCE OF BLOOD "EXCESS LACTATE" IN THE NEWBORN PERIOD.
Topics: Asphyxia Neonatorum; Biomedical Research; Blood Glucose; Carbohydrate Metabolism; Cesarean Section; | 1964 |
Long-term follow-up of neonatal mitochondrial cytopathies: a study of 57 patients.
Topics: Child, Preschool; Disease Progression; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; I | 2005 |
Brain metabolism during prolonged seizures in neonates.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Glucose; Haplorhini; Humans; Infant, Newborn; Infan | 1983 |
Screening of high risk infants for metabolic disease in a metropolitan hospital.
Topics: Amino Acids; Ammonia; Carboxylic Acids; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lactates | 1981 |
Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH.
Topics: Acid-Base Imbalance; Asphyxia Neonatorum; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxant | 1982 |
[Iron absorption in low birth weight and anemic infants (author's transl)].
Topics: Anemia, Hypochromic; Animals; Cattle; Female; Gestational Age; Humans; Infant; Infant Food; Infant, | 1981 |
Association between blood lactate and acid-base status and mortality in ventilated babies.
Topics: Acid-Base Equilibrium; Biomarkers; Female; Humans; Infant Mortality; Infant, Newborn; Infant, Newbor | 1997 |
A comparison of hexachlorophene and lactacyd on growth of skin flora in healthy term newborn infants.
Topics: Antisepsis; Bacteria; Drug Combinations; Hexachlorophene; Humans; Immune Sera; Infant, Newborn; Infa | 1974 |