lactic acid has been researched along with Ichthyosis in 12 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Ichthyosis: Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ninety-two patients were enrolled; 41 of these were excluded from analysis (25 were lost to follow-up, 8 were noncompliant, 1 was discharged from study because of an adverse event after visit 1, and 7 were noncompliant after visit 2)." | 2.71 | A double-blind clinical trial comparing the efficacy and safety of pure lanolin versus ammonium lactate 12% cream for the treatment of moderate to severe foot xerosis. ( Alfieri, DM; Goodwin, S; Jackman, L; Jennings, MB; Lesczczynski, C; Parker, ER, 2003) |
| "Netherton's syndrome is a rare symptom complex characterized by greatly elevated IgE levels with atopic manifestations, an ichthyotic skin disorder (ichthyosis linearis circumflexa and/or congenital lamellar ichthyosis), and the characteristic hair abnormality trichorrhexis invaginata." | 2.39 | Netherton's syndrome: a syndrome of elevated IgE and characteristic skin and hair findings. ( deShazo, RD; Smith, DL; Smith, JG; Wong, SW, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danby, SG | 1 |
| Brown, K | 1 |
| Higgs-Bayliss, T | 1 |
| Chittock, J | 1 |
| Albenali, L | 1 |
| Cork, MJ | 1 |
| Machan, M | 1 |
| Kestenbaum, T | 1 |
| Fraga, GR | 1 |
| Jennings, MB | 1 |
| Alfieri, DM | 1 |
| Parker, ER | 1 |
| Jackman, L | 1 |
| Goodwin, S | 1 |
| Lesczczynski, C | 1 |
| Smith, DL | 1 |
| Smith, JG | 1 |
| Wong, SW | 1 |
| deShazo, RD | 1 |
| Sanclemente, G | 1 |
| Falabella, R | 1 |
| Escobar, CE | 1 |
| Arroyave, JA | 1 |
| Ademola, J | 1 |
| Frazier, C | 1 |
| Kim, SJ | 1 |
| Theaux, C | 1 |
| Saudez, X | 1 |
| Wehr, RF | 2 |
| Kantor, I | 1 |
| Jones, EL | 1 |
| McPhee, ME | 1 |
| Krochmal, L | 3 |
| Van Scott, EJ | 1 |
| Yu, RJ | 1 |
| Rogers, RS | 1 |
| Callen, J | 1 |
| Wehr, R | 1 |
| Buxman, M | 1 |
| Hickman, J | 1 |
| Ragsdale, W | 1 |
| Stretcher, G | 1 |
| Beverley, DW | 1 |
| Wheeler, D | 1 |
| Garty, BZ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Pathology Assessment With Optical Technologies (SPOT): a Cross- Sectional Clinical Study in Atopic Dermatitis Patients and Healthy Subjects[NCT04295824] | 80 participants (Anticipated) | Observational | 2020-08-06 | Recruiting | |||
| Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valera[NCT04194814] | Phase 2 | 37 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Ichthyosis
| Article | Year |
|---|---|
Netherton's syndrome: a syndrome of elevated IgE and characteristic skin and hair findings.
Topics: Biopsy, Needle; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Hair; Hair Dis | 1995 |
5 trials available for lactic acid and Ichthyosis
| Article | Year |
|---|---|
A double-blind clinical trial comparing the efficacy and safety of pure lanolin versus ammonium lactate 12% cream for the treatment of moderate to severe foot xerosis.
Topics: Administration, Topical; Adult; Aged; Double-Blind Method; Drug Combinations; Female; Follow-Up Stud | 2003 |
Clinical evaluation of 40% urea and 12% ammonium lactate in the treatment of xerosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedul | 2002 |
A controlled comparative efficacy study of 5% ammonium lactate lotion versus an emollient control lotion in the treatment of moderate xerosis.
Topics: Double-Blind Method; Emollients; Female; Humans; Ichthyosis; Lactates; Lactic Acid; Leg; Lipids; Mid | 1991 |
Comparative efficacy of 12% ammonium lactate lotion and 5% lactic acid lotion in the treatment of moderate to severe xerosis.
Topics: Adult; Aged; Double-Blind Method; Drug Evaluation; Female; Humans; Ichthyosis; Lactates; Lactic Acid | 1989 |
Therapeutic activity of lactate 12% lotion in the treatment of ichthyosis. Active versus vehicle and active versus a petrolatum cream.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Clinic | 1986 |
6 other studies available for lactic acid and Ichthyosis
| Article | Year |
|---|---|
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
Diffuse hyperkeratosis in a deaf and blind 48-year-old woman--quiz case. Diagnosis: keratitis-ichthyosis-deafness (KID) syndrome with secondary dermatophytosis.
Topics: Antifungal Agents; Baths; Blindness; Deafness; Dermatologic Agents; Female; Fluconazole; Humans; Ich | 2012 |
Ichthyosis bullosa of Siemens: a topical therapy option.
Topics: Administration, Topical; Antipruritics; Child; Humans; Ichthyosis; Lactic Acid; Male; Propionates; Q | 1999 |
Alpha hydroxy acids: procedures for use in clinical practice.
Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic | 1989 |
High plasma urea concentrations in collodion babies.
Topics: Betaine; Drug Combinations; Female; Humans; Ichthyosis; Infant, Newborn; Lactates; Lactic Acid; Skin | 1986 |
High plasma urea concentration in babies with lamellar ichthyosis.
Topics: Drug Combinations; Humans; Ichthyosis; Infant; Infant, Newborn; Lactates; Lactic Acid; Skin Absorpti | 1986 |