Page last updated: 2024-10-17

lactic acid and Ichthyosis

lactic acid has been researched along with Ichthyosis in 12 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Ichthyosis: Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.

Research Excerpts

ExcerptRelevanceReference
" Ninety-two patients were enrolled; 41 of these were excluded from analysis (25 were lost to follow-up, 8 were noncompliant, 1 was discharged from study because of an adverse event after visit 1, and 7 were noncompliant after visit 2)."2.71A double-blind clinical trial comparing the efficacy and safety of pure lanolin versus ammonium lactate 12% cream for the treatment of moderate to severe foot xerosis. ( Alfieri, DM; Goodwin, S; Jackman, L; Jennings, MB; Lesczczynski, C; Parker, ER, 2003)
"Netherton's syndrome is a rare symptom complex characterized by greatly elevated IgE levels with atopic manifestations, an ichthyotic skin disorder (ichthyosis linearis circumflexa and/or congenital lamellar ichthyosis), and the characteristic hair abnormality trichorrhexis invaginata."2.39Netherton's syndrome: a syndrome of elevated IgE and characteristic skin and hair findings. ( deShazo, RD; Smith, DL; Smith, JG; Wong, SW, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danby, SG1
Brown, K1
Higgs-Bayliss, T1
Chittock, J1
Albenali, L1
Cork, MJ1
Machan, M1
Kestenbaum, T1
Fraga, GR1
Jennings, MB1
Alfieri, DM1
Parker, ER1
Jackman, L1
Goodwin, S1
Lesczczynski, C1
Smith, DL1
Smith, JG1
Wong, SW1
deShazo, RD1
Sanclemente, G1
Falabella, R1
Escobar, CE1
Arroyave, JA1
Ademola, J1
Frazier, C1
Kim, SJ1
Theaux, C1
Saudez, X1
Wehr, RF2
Kantor, I1
Jones, EL1
McPhee, ME1
Krochmal, L3
Van Scott, EJ1
Yu, RJ1
Rogers, RS1
Callen, J1
Wehr, R1
Buxman, M1
Hickman, J1
Ragsdale, W1
Stretcher, G1
Beverley, DW1
Wheeler, D1
Garty, BZ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Skin Pathology Assessment With Optical Technologies (SPOT): a Cross- Sectional Clinical Study in Atopic Dermatitis Patients and Healthy Subjects[NCT04295824]80 participants (Anticipated)Observational2020-08-06Recruiting
Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valera[NCT04194814]Phase 237 participants (Actual)Interventional2020-11-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lactic acid and Ichthyosis

ArticleYear
Netherton's syndrome: a syndrome of elevated IgE and characteristic skin and hair findings.
    The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:1 Pt 1

    Topics: Biopsy, Needle; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Hair; Hair Dis

1995

Trials

5 trials available for lactic acid and Ichthyosis

ArticleYear
A double-blind clinical trial comparing the efficacy and safety of pure lanolin versus ammonium lactate 12% cream for the treatment of moderate to severe foot xerosis.
    Cutis, 2003, Volume: 71, Issue:1

    Topics: Administration, Topical; Adult; Aged; Double-Blind Method; Drug Combinations; Female; Follow-Up Stud

2003
Clinical evaluation of 40% urea and 12% ammonium lactate in the treatment of xerosis.
    American journal of clinical dermatology, 2002, Volume: 3, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedul

2002
A controlled comparative efficacy study of 5% ammonium lactate lotion versus an emollient control lotion in the treatment of moderate xerosis.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:5 Pt 1

    Topics: Double-Blind Method; Emollients; Female; Humans; Ichthyosis; Lactates; Lactic Acid; Leg; Lipids; Mid

1991
Comparative efficacy of 12% ammonium lactate lotion and 5% lactic acid lotion in the treatment of moderate to severe xerosis.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:4 Pt 1

    Topics: Adult; Aged; Double-Blind Method; Drug Evaluation; Female; Humans; Ichthyosis; Lactates; Lactic Acid

1989
Therapeutic activity of lactate 12% lotion in the treatment of ichthyosis. Active versus vehicle and active versus a petrolatum cream.
    Journal of the American Academy of Dermatology, 1986, Volume: 15, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Clinic

1986

Other Studies

6 other studies available for lactic acid and Ichthyosis

ArticleYear
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
    Skin pharmacology and physiology, 2016, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi

2016
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
    Skin pharmacology and physiology, 2016, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi

2016
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
    Skin pharmacology and physiology, 2016, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi

2016
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
    Skin pharmacology and physiology, 2016, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi

2016
Diffuse hyperkeratosis in a deaf and blind 48-year-old woman--quiz case. Diagnosis: keratitis-ichthyosis-deafness (KID) syndrome with secondary dermatophytosis.
    Archives of dermatology, 2012, Volume: 148, Issue:10

    Topics: Antifungal Agents; Baths; Blindness; Deafness; Dermatologic Agents; Female; Fluconazole; Humans; Ich

2012
Ichthyosis bullosa of Siemens: a topical therapy option.
    Archives of dermatology, 1999, Volume: 135, Issue:2

    Topics: Administration, Topical; Antipruritics; Child; Humans; Ichthyosis; Lactic Acid; Male; Propionates; Q

1999
Alpha hydroxy acids: procedures for use in clinical practice.
    Cutis, 1989, Volume: 43, Issue:3

    Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic

1989
High plasma urea concentrations in collodion babies.
    Archives of disease in childhood, 1986, Volume: 61, Issue:7

    Topics: Betaine; Drug Combinations; Female; Humans; Ichthyosis; Infant, Newborn; Lactates; Lactic Acid; Skin

1986
High plasma urea concentration in babies with lamellar ichthyosis.
    Archives of disease in childhood, 1986, Volume: 61, Issue:12

    Topics: Drug Combinations; Humans; Ichthyosis; Infant; Infant, Newborn; Lactates; Lactic Acid; Skin Absorpti

1986