Page last updated: 2024-10-17

lactic acid and Hypovolemia

lactic acid has been researched along with Hypovolemia in 11 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Hypovolemia: An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to examine the impact of a novel NHE1 inhibitor, sabiporide, on cardiovascular function, blood oxygen transportation, and inflammatory response in an experimental model of metabolic acidosis produced by hemorrhage-induced hypovolemia followed by an infusion of lactic acid."7.79Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. ( Abraham, WM; Kraut, JA; Wu, D, 2013)
" The authors investigated the influence of hypovolemia on the effect of an inhalation anesthetic, isoflurane, in a swine hemorrhage model."7.73Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model. ( Fukuda, K; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2005)
" The aim of the present study was to examine the impact of a novel NHE1 inhibitor, sabiporide, on cardiovascular function, blood oxygen transportation, and inflammatory response in an experimental model of metabolic acidosis produced by hemorrhage-induced hypovolemia followed by an infusion of lactic acid."3.79Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. ( Abraham, WM; Kraut, JA; Wu, D, 2013)
"Under both normovolemia and hypovolemia, glucose levels in rats anesthetized with sevoflurane were significantly higher than those in rats anesthetized with propofol, and insulin levels in rats anesthetized with sevoflurane were significantly lower than those in rats anesthetized with propofol."3.78The involvement of adenosine triphosphate-sensitive potassium channels in the different effects of sevoflurane and propofol on glucose metabolism in fed rats. ( Kawamura, G; Kitamura, T; Sato, K; Yamada, Y, 2012)
" The authors investigated the influence of hypovolemia on the effect of an inhalation anesthetic, isoflurane, in a swine hemorrhage model."3.73Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model. ( Fukuda, K; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2005)
"Hypovolemia was induced and maintained for 20 min by removal of 50% of the total blood volume; thereafter, the animals were retransfused."1.56Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model. ( Bischoff, SJ; Irintchev, A; Lehmann, T; Lemke, C; Nistor, M; Schiffner, R; Schmidt, M, 2020)
"Circulatory failure is frequent in intensive care unit (ICU) patients and is associated with a high mortality and morbidity."1.39Variable assessment of the circulation in intensive care unit patients with shock. ( Haase, N; Hennings, LI; Perner, A, 2013)
"Sepsis was induced by intravenous administration of E."1.37A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis. ( Ferko, A; Havel, E; Hyspler, R; Koci, J; Lochman, P; Oberreiter, M; Ticha, A; Valis, M, 2011)
"Patients with either septic shock or lactate >or=4."1.34Occult hypoperfusion and mortality in patients with suspected infection. ( Clardy, P; Donnino, M; Howell, MD; Shapiro, NI; Talmor, D, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Schiffner, R1
Bischoff, SJ1
Lehmann, T1
Irintchev, A1
Nistor, M1
Lemke, C1
Schmidt, M1
Schiller, AM1
Howard, JT1
Lye, KR1
Magby, CG1
Convertino, VA1
Hennings, LI1
Haase, N1
Perner, A1
Gurji, HA1
White, DW1
Hoxha, B1
Sun, J1
Harbor, JP1
Schulz, DR1
Williams, AG1
Olivencia-Yurvati, AH1
Mallet, RT1
Koci, J1
Oberreiter, M1
Hyspler, R1
Ticha, A1
Valis, M1
Lochman, P1
Havel, E1
Ferko, A1
Kitamura, T1
Sato, K1
Kawamura, G1
Yamada, Y1
Wu, D1
Kraut, JA1
Abraham, WM1
Kurita, T1
Morita, K1
Fukuda, K1
Uraoka, M1
Takata, K1
Sanjo, Y1
Sato, S1
Rixen, D1
Siegel, JH1
Sennoun, N1
Montemont, C1
Gibot, S1
Lacolley, P1
Levy, B1
Howell, MD1
Donnino, M1
Clardy, P1
Talmor, D1
Shapiro, NI1

Reviews

1 review available for lactic acid and Hypovolemia

ArticleYear
Bench-to-bedside review: oxygen debt and its metabolic correlates as quantifiers of the severity of hemorrhagic and post-traumatic shock.
    Critical care (London, England), 2005, Oct-05, Volume: 9, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Disease Models, Animal; Dogs; Humans; Hypovolemia; Hypoxia

2005

Other Studies

10 other studies available for lactic acid and Hypovolemia

ArticleYear
Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model.
    International journal of molecular sciences, 2020, Feb-27, Volume: 21, Issue:5

    Topics: Animals; Arterioles; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypovolemia; Hypoxi

2020
Comparisons of Traditional Metabolic Markers and Compensatory Reserve as Early Predictors of Tolerance to Central Hypovolemia in Humans.
    Shock (Augusta, Ga.), 2018, Volume: 50, Issue:1

    Topics: Adult; Blood Pressure; Female; Heart Rate; Hemodynamics; Hemorrhage; Humans; Hypovolemia; Lactic Aci

2018
Variable assessment of the circulation in intensive care unit patients with shock.
    Danish medical journal, 2013, Volume: 60, Issue:9

    Topics: Arterial Pressure; Cardiac Output; Clinical Competence; Critical Care; Diuresis; Fluid Therapy; Hear

2013
Pyruvate-enriched resuscitation: metabolic support of post-ischemic hindlimb muscle in hypovolemic goats.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:2

    Topics: Animals; Antioxidants; Citric Acid; Dinoprost; Goats; Hypovolemia; Infusions, Intravenous; Lactic Ac

2014
A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis.
    Neuro endocrinology letters, 2011, Volume: 32, Issue:3

    Topics: Animals; Blood Glucose; Crystalloid Solutions; Escherichia coli Infections; Fluid Therapy; Glycerol;

2011
The involvement of adenosine triphosphate-sensitive potassium channels in the different effects of sevoflurane and propofol on glucose metabolism in fed rats.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Glucose; Blood Pressure; Disease M

2012
Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Acidosis; Animals; Cardiovascular System; Cation Transport Proteins; Familial Primary Pulmonary Hype

2013
Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model.
    Anesthesiology, 2005, Volume: 102, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Electroencep

2005
Comparative effects of early versus delayed use of norepinephrine in resuscitated endotoxic shock.
    Critical care medicine, 2007, Volume: 35, Issue:7

    Topics: Animals; Blood Pressure; Coronary Circulation; Drug Administration Schedule; Endotoxins; Fluid Thera

2007
Occult hypoperfusion and mortality in patients with suspected infection.
    Intensive care medicine, 2007, Volume: 33, Issue:11

    Topics: Aged; Aged, 80 and over; Cohort Studies; Early Diagnosis; Female; Hospital Mortality; Hospitals, Uni

2007