Page last updated: 2024-10-17

lactic acid and Hypotension

lactic acid has been researched along with Hypotension in 97 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Studies in healthy patients undergoing elective caesarean delivery show that, compared with phenylephrine, ephedrine used to treat spinal hypotension is associated with increased fetal acidosis."9.27A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise. ( Adams, SC; Arcache, MJ; Dyer, RA; Emmanuel, A; Higgins, N; James, MF; Joolay, Y; Lombard, CJ; Reed, AR; Schulein, S; van Dyk, D; Vorster, A; Wong, CA, 2018)
"At 115-136 days of gestation, chronically instrumented, anesthetized ewes with either normal placental function or increased placental vascular resistance after placental embolization were randomized to receive boluses of ephedrine (n = 12) or phenylephrine (n = 12) for epidural-induced hypotension after a short period of hypoxemia."7.74Divergent effects of ephedrine and phenylephrine on cardiovascular hemodynamics of near-term fetal sheep exposed to hypoxemia and maternal hypotension. ( Acharya, G; Alahuhta, S; Erkinaro, T; Huhta, JC; Kavasmaa, T; Mäkikallio, K; Päkkilä, M; Räsänen, J, 2007)
" Twenty-four hours after embolization, the ewes were anaesthetized and randomized to receive boluses of ephedrine (n=7) or phenylephrine (n=6) for epidural-induced hypotension after maternal hypoxaemia."7.73Ephedrine and phenylephrine for the treatment of maternal hypotension in a chronic sheep model of increased placental vascular resistance. ( Acharya, G; Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Päkkilä, M; Räsänen, J, 2006)
"At 117-132 days gestation, chronically instrumented, anaesthetized and mechanically ventilated ewes were randomized to receive boluses of ephedrine (n=9) or phenylephrine (n=8) for maternal epidural-induced hypotension after a period of fetal hypoxaemia."7.72Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model. ( Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Räsänen, J, 2004)
"Twelve pigs were randomized to receive either vasopressin (VASO, n = 6) or vasopressin in combination with dobutamine (DOBU, n = 6) during endotoxin shock (E."7.72Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock. ( Martikainen, TJ; Ruokonen, E; Tenhunen, JJ; Uusaro, A, 2004)
"Local effects of dopexamine on intestinal vascular tone and oxygenation were investigated during intestinal hypotension."7.71Does dopexamine influence regional vascular tone and oxygenation during intestinal hypotension? ( Arnerlöv, C; Biber, B; Fröjse, R; Johansson, G; Lehtipalo, S; Winsö, O, 2002)
" In six dogs the effects of etomidate (5 mg X kg-1) on the rates of adenosine triphosphate (ATP) and phosphocreatine (PCr) depletion and lactate accumulation during 9 min of oligemic hypotension to 31 mmHg were compared with six untreated dogs."7.67Preservation of cerebral metabolites by etomidate during incomplete cerebral ischemia in dogs. ( Milde, JH; Milde, LN, 1986)
"Studies in healthy patients undergoing elective caesarean delivery show that, compared with phenylephrine, ephedrine used to treat spinal hypotension is associated with increased fetal acidosis."5.27A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise. ( Adams, SC; Arcache, MJ; Dyer, RA; Emmanuel, A; Higgins, N; James, MF; Joolay, Y; Lombard, CJ; Reed, AR; Schulein, S; van Dyk, D; Vorster, A; Wong, CA, 2018)
"In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia."5.13Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*. ( Chui, K; Khaw, KS; Lau, TK; Ng, FF; Ng, KL; Ngan Kee, WD, 2008)
"To determine the effects on hemodynamics, laboratory parameters, and renal function of terlipressin used in septic-shock patients with hypotension not responsive to high-dose norepinephrine (>2."5.11Terlipressin in catecholamine-resistant septic shock patients. ( Albanèse, J; Chaabane, W; Delmas, A; Garnier, F; Leone, M; Martin, C, 2004)
" Emergency physicians may consider the development of hypotension, high creatine, lactate, base excess, low bicarbonate, and blood pH to be associated with a poor prognosis in the first hours of admission in acute poisoning patients."4.12Prospective analysis of intoxicated patients developing shock and/or organ failure. ( Akday, U; Akpınar, AA; Dişel, NR; Karakoç, E; Taşkın, Ö; Tekin, F, 2022)
" The patient showed severe intraoperative hypotension, lactic acidosis, and complete abolition of motor-evoked potentials during the positioning of posterior corrective bars."3.96Liver and skeletal muscle injury in a 12-year-old female patient after scoliosis correction in prone position: a case report. ( Bacchin, R; Feoli, A; Ghisi, D; Greggi, T; Morigi, A, 2020)
"At 115-136 days of gestation, chronically instrumented, anesthetized ewes with either normal placental function or increased placental vascular resistance after placental embolization were randomized to receive boluses of ephedrine (n = 12) or phenylephrine (n = 12) for epidural-induced hypotension after a short period of hypoxemia."3.74Divergent effects of ephedrine and phenylephrine on cardiovascular hemodynamics of near-term fetal sheep exposed to hypoxemia and maternal hypotension. ( Acharya, G; Alahuhta, S; Erkinaro, T; Huhta, JC; Kavasmaa, T; Mäkikallio, K; Päkkilä, M; Räsänen, J, 2007)
" Twenty-four hours after embolization, the ewes were anaesthetized and randomized to receive boluses of ephedrine (n=7) or phenylephrine (n=6) for epidural-induced hypotension after maternal hypoxaemia."3.73Ephedrine and phenylephrine for the treatment of maternal hypotension in a chronic sheep model of increased placental vascular resistance. ( Acharya, G; Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Päkkilä, M; Räsänen, J, 2006)
"At 117-132 days gestation, chronically instrumented, anaesthetized and mechanically ventilated ewes were randomized to receive boluses of ephedrine (n=9) or phenylephrine (n=8) for maternal epidural-induced hypotension after a period of fetal hypoxaemia."3.72Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model. ( Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Räsänen, J, 2004)
"Twelve pigs were randomized to receive either vasopressin (VASO, n = 6) or vasopressin in combination with dobutamine (DOBU, n = 6) during endotoxin shock (E."3.72Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock. ( Martikainen, TJ; Ruokonen, E; Tenhunen, JJ; Uusaro, A, 2004)
"Local effects of dopexamine on intestinal vascular tone and oxygenation were investigated during intestinal hypotension."3.71Does dopexamine influence regional vascular tone and oxygenation during intestinal hypotension? ( Arnerlöv, C; Biber, B; Fröjse, R; Johansson, G; Lehtipalo, S; Winsö, O, 2002)
" The principal findings included metabolic acidosis accompanied by an increase in the plasma anion gap that was not caused by L -lactic acidosis, hyperkalemia, and the abrupt onset of hypotension."3.71Citric acid ingestion: a life-threatening cause of metabolic acidosis. ( DeMars, CS; Halperin, ML; Himmelfarb, J; Hollister, K; Tomassoni, A, 2001)
"The study investigated whether hypotension in halothane-anaesthetised ponies is the stimulus inducing an endocrine stress response by assessing the effect of maintenance of normotension with a dobutamine infusion."3.70Adrenocortical and metabolic responses to dobutamine infusion during halothane anaesthesia in ponies. ( Taylor, PM, 1998)
" In six dogs the effects of etomidate (5 mg X kg-1) on the rates of adenosine triphosphate (ATP) and phosphocreatine (PCr) depletion and lactate accumulation during 9 min of oligemic hypotension to 31 mmHg were compared with six untreated dogs."3.67Preservation of cerebral metabolites by etomidate during incomplete cerebral ischemia in dogs. ( Milde, JH; Milde, LN, 1986)
"Cerebral blood flow (CBF, by laser Doppler flowmetry) and extracellular cortical concentrations (by microdialysis) of adenosine, inosine, xanthine, hypoxanthine, and lactate were measured together with somatosensory evoked potentials (SEP) in chloralose-anaesthetized spontaneously hypertensive rats (SHR) during relative cerebral ischemia induced by hypotensive hemorrhage."3.67Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites. ( Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P, 1989)
"Fluid resuscitation is recommended in septic shock, but the specific indications for fluids have not been established."2.90Indications for fluid resuscitation in patients with septic shock: Post-hoc analyses of the CLASSIC trial. ( Bjerregaard, MR; Hjortrup, PB; Perner, A, 2019)
"We enrolled 30 patients with septic shock requiring invasive hemodynamic monitoring and norepinephrine infusion of 0."2.73Glibenclamide dose response in patients with septic shock: effects on norepinephrine requirements, cardiopulmonary performance, and global oxygen transport. ( Bachetoni, A; Broeking, K; Ertmer, C; Landoni, G; Lange, M; Morelli, A; Orecchioni, A; Pietropaoli, P; Rocco, M; Traber, DL; Van Aken, H; Westphal, M, 2007)
"Cardiogenic shock has the potential for significant morbidity and mortality if not recognized early."2.66Identifying cardiogenic shock in the emergency department. ( Daly, M; Koyfman, A; Lentz, S; Long, B, 2020)
"Accordingly, sepsis is now defined as a life-threatening organ dysfunction due to a falsely regulated response of the body to an infection."2.55[Updated definition of sepsis : Implications for diagnostics and therapy principles]. ( Schlegel, N, 2017)
"Sepsis is a global health problem."2.49[Initial resuscitation bundle and monitoring tissue perfusion in severe sepsis]. ( Hernández P, G; Romero P, C, 2013)
"The recognition of severe sepsis should be accompanied without delay by very well defined therapeutic measures."2.43The role of bundles in sepsis care. ( Hurtado, FJ; Nin, N, 2006)
"Endotoxemia was induced by systemic injection of lipopolysaccharide (LPS) (1."1.62Central Administration of Angiotensin-(1-7) Improves Vasopressin Impairment and Hypotensive Response in Experimental Endotoxemia. ( Antunes-Rodrigues, J; Batalhão, ME; Bendhack, LM; Capellari Carnio, E; de Lima Faim, F; Lacchini, R; Passaglia, P; Stabile, AM, 2021)
"Hypotension was defined as systolic blood pressure <90 mm Hg or mean arterial pressure <60 mm Hg, and hypoperfusion as admission lactate >2 mmol/L, oliguria, or rising creatinine."1.62Defining Shock and Preshock for Mortality Risk Stratification in Cardiac Intensive Care Unit Patients. ( Baran, DA; Barsness, GW; Bell, MR; Burstein, B; Henry, TD; Holmes, DR; Jentzer, JC; Menon, V; Murphy, J; Naidu, SS; Rihal, CS; Van Diepen, S, 2021)
"Maternal sepsis is a significant cause of maternal morbidity and mortality and is a preventable cause of maternal death."1.51SMFM Consult Series #47: Sepsis during pregnancy and the puerperium. ( Louis, JM; Pacheco, LD; Plante, LA, 2019)
"Prognostication in sepsis is limited by disease heterogeneity, and measures to risk-stratify patients in the proximal phases of care lack simplicity and accuracy."1.48Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department. ( Aydin, A; Dziura, JD; Reynolds, J; Swenson, KE; Wira, CR, 2018)
"It seems reasonable for septic shock to be defined by the lactate levels after volume resuscitation."1.48Prognosis of patients excluded by the definition of septic shock based on their lactate levels after initial fluid resuscitation: a prospective multi-center observational study. ( Beom, JH; Choi, HS; Choi, SH; Chung, SP; Han, KS; Jo, YH; Kang, GH; Kim, K; Kim, WY; Ko, BS; Kwon, WY; Lim, TH; Ryoo, SM; Shin, TG; Suh, GJ, 2018)
"Patients with culture-negative septic shock behave similarly to those with culture-positive septic shock in nearly all respects; early appropriate antimicrobial therapy appears to improve mortality."1.48Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study. ( Bilgili, B; Kethireddy, S; Kirchner, HL; Kumar, A; Layon, AJ; Light, RB; Maki, D; Mirzanejad, Y; Ofoma, UR; Parrillo, JE; Sees, A, 2018)
"Septic shock was associated with reduced renal perfusion and decreased cortical and medullary blood flow, followed by signs of anaerobic metabolism in the cortex when flow reductions became critical."1.46Changes in kidney perfusion and renal cortex metabolism in septic shock: an experimental study. ( Creteur, J; De Backer, D; Herpain, A; Hosokawa, K; Post, EH; Su, F; Taccone, FS; Vincent, JL, 2017)
"Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis."1.43Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). ( Angus, DC; Brunkhorst, FM; Deutschman, CS; Escobar, GJ; Iwashyna, TJ; Kahn, JM; Liu, VX; Rea, TD; Rubenfeld, G; Scherag, A; Seymour, CW; Shankar-Hari, M; Singer, M, 2016)
" HRT caused no adverse effects like electrolyte disturbances or hyperglycaemia."1.42Safety, efficacy and response to a hydrocortisone rescue therapy protocol in children with refractory hypotension after cardiopulmonal bypass. ( Gerbig, I; Grenz, Ch; Haller, Ch; Heimberg, E; Hofbeck, M; Kumpf, M; Neunhoeffer, F; Renk, H; Schlensak, Ch, 2015)
""Cryptic shock" was defined as severe sepsis with a lactate level of 4 mmol/L or greater and normotension, "COS" was defined as initial CS that progressed to septic shock within 72 h, and "OS" was defined as septic shock on ED arrival."1.40Association between hemodynamic presentation and outcome in sepsis patients. ( Cha, WC; Hwang, SY; Jeon, K; Jeong, YK; Jo, IJ; Lee, TR; Shin, TG; Sim, MS; Song, KJ; Suh, GY, 2014)
"Sepsis was defined as suspected infection plus two or more systemic inflammatory response syndrome (SIRS) criteria; those with hypotension were excluded."1.40The microcirculation is preserved in emergency department low-acuity sepsis patients without hypotension. ( Barche, A; Bracey, A; Chang, Y; Filbin, MR; Hou, PC; Kao, E; Massey, M; Shapiro, NI; Skibsted, S, 2014)
"Sepsis is a serious worldwide health care condition that is associated with high mortality rates, despite improvements in the ability to manage infection."1.39Implications of the new international sepsis guidelines for nursing care. ( Aitken, L; Kleinpell, R; Schorr, CA, 2013)
"Patients with septic shock state prior to initial presentation has a lower 30 day survival compared to any other septic conditions."1.38The use of laboratory and physiological parameters in predicting mortality in sepsis induced hypotension and septic shock patients attending the emergency department. ( Azlan, K; Hisamuddin, NA, 2012)
" Reduced IC combined with intracranial volume insults leads to metabolic disturbances in a rat model."1.36Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat. ( Contant, CF; Enblad, P; Goiny, M; Nilsson, P; Piper, I; Salci, K, 2010)
"Six rats died due to hemorrhagic shock by 350 min (Group D) while six rats had survived for the 350 min period after exsanguination (Group A)."1.35Utility of microdialysis to detect the lactate/pyruvate ratio in subcutaneous tissue for the reliable monitoring of hemorrhagic shock. ( Fujitani, S; Hosoyama, A; Kawasaki, N; Kobayashi, K; Ohashi, H; Ohashi, M; Taira, Y; Wada, T, 2009)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-19904 (4.12)18.7374
1990's11 (11.34)18.2507
2000's26 (26.80)29.6817
2010's40 (41.24)24.3611
2020's16 (16.49)2.80

Authors

AuthorsStudies
Kędziora, A1
Piątek, J1
Hymczak, H1
Wasilewski, G1
Guzik, B1
Drwiła, R1
Kapelak, B1
Sobczyk, D1
Konstanty-Kalandyk, J1
Wierzbicki, K1
Sumbal, R1
Ali Baig, MM1
Sumbal, A1
Khalil, MA1
El Tahan, MR1
Khidr, AM1
Fallatah, S1
Abohamar, AD1
Amer, MM1
Makhdom, F1
El Ghoneimy, Y1
Al Bassam, B1
Alghamdi, T1
Abdulfattah, D1
Tekin, F3
Akpınar, AA3
Taşkın, Ö3
Akday, U3
Dişel, NR3
Karakoç, E3
Kuttab, HI1
Evans, CG1
Lykins, JD1
Hughes, MD1
Kopec, JA1
Hernandez, MA1
Ward, MA1
Bacchin, R1
Feoli, A1
Morigi, A1
Ghisi, D1
Greggi, T1
Letson, HL1
Granfeldt, A1
Jensen, TH1
Mattson, TH1
Dobson, GP1
Wolf, JM1
Stefanovski, D1
Silverstein, DC1
Phad, N1
de Waal, K1
Daly, M1
Long, B1
Koyfman, A1
Lentz, S1
Issa, MS2
Grossestreuer, AV1
Patel, H1
Ntshinga, L1
Coker, A1
Yankama, T1
Donnino, MW3
Berg, KM2
Passaglia, P1
de Lima Faim, F1
Batalhão, ME1
Stabile, AM1
Bendhack, LM1
Antunes-Rodrigues, J2
Lacchini, R1
Capellari Carnio, E1
Jentzer, JC1
Burstein, B1
Van Diepen, S1
Murphy, J1
Holmes, DR1
Bell, MR1
Barsness, GW1
Henry, TD1
Menon, V1
Rihal, CS1
Naidu, SS1
Baran, DA1
Djarv, T1
Jeyaraju, M1
McCurdy, MT1
Levine, AR1
Devarajan, P1
Mazzeffi, MA1
Mullins, KE1
Reif, M1
Yim, DN1
Parrino, C1
Lankford, AS1
Chow, JH1
Dyer, RA1
Emmanuel, A1
Adams, SC1
Lombard, CJ1
Arcache, MJ1
Vorster, A1
Wong, CA1
Higgins, N1
Reed, AR1
James, MF1
Joolay, Y1
Schulein, S1
van Dyk, D1
Kethireddy, S1
Bilgili, B1
Sees, A1
Kirchner, HL1
Ofoma, UR1
Light, RB1
Mirzanejad, Y1
Maki, D1
Kumar, A4
Layon, AJ1
Parrillo, JE2
Ferreira, SADS1
Moraes, AC1
Terzi, RGG1
Ferreira, ELA1
Silva, WA1
Moreira, MM1
Souza, LR1
Vicente, JB1
Melo, GR1
Moraes, VC1
Olher, RR1
Sousa, IC1
Peruchi, LH1
Neves, RV1
Rosa, TS1
Ferreira, AP1
Moraes, MR1
Ko, BS1
Kim, K1
Choi, SH1
Kang, GH1
Shin, TG2
Jo, YH1
Ryoo, SM1
Beom, JH1
Kwon, WY1
Han, KS1
Choi, HS1
Chung, SP1
Suh, GJ1
Lim, TH1
Kim, WY1
Bjerregaard, MR1
Hjortrup, PB1
Perner, A1
Plante, LA1
Pacheco, LD1
Louis, JM1
Hallisey, SD1
Greenwood, JC1
Lin, GS1
Chou, TH1
Wu, CY1
Wu, MC1
Fang, CC1
Yen, ZS1
Lee, CC1
Chen, SC1
Kleinpell, R1
Aitken, L1
Schorr, CA1
Collange, O1
Tamion, F1
Meyer, N1
Quillard, M1
Kindo, M1
Hue, G1
Veber, B1
Dureuil, B1
Plissonnier, D1
Pattarini, JM1
Blue, RS1
Aikins, LT1
Law, J1
Walshe, AD1
Garbino, A1
Turney, MW1
Clark, JB1
Cevik, AA1
Dolgun, H1
Oner, S1
Tokar, B1
Acar, N1
Ozakin, E1
Kaya, F1
Romero P, C1
Hernández P, G1
Filbin, MR1
Hou, PC1
Massey, M1
Barche, A1
Kao, E1
Bracey, A1
Skibsted, S1
Chang, Y1
Shapiro, NI1
Lear, CA1
Davidson, JO1
Booth, LC1
Wassink, G1
Galinsky, R1
Drury, PP1
Fraser, M1
Bennet, L1
Gunn, AJ1
Hwang, SY1
Jo, IJ1
Jeon, K1
Suh, GY1
Lee, TR1
Cha, WC1
Sim, MS1
Song, KJ1
Jeong, YK1
Neunhoeffer, F1
Renk, H1
Hofbeck, M1
Grenz, Ch1
Haller, Ch1
Heimberg, E1
Gerbig, I1
Schlensak, Ch1
Kumpf, M1
Lin, RL1
Lin, YJ1
Xu, F1
Lee, LY1
Lopez, EM1
Ghetmiri, E1
Gettle, LM1
Reed, MF1
McAllister, BP1
Lokhandwala, S1
Moskowitz, A1
Lawniczak, R1
Giberson, T1
Cocchi, MN1
Vantrease, JE1
Dudek, N1
DonCarlos, LL1
Scrogin, KE1
Hynes, D1
Bates, S1
Loughman, A1
Klim, S1
French, C1
Kelly, AM1
Scott, HF1
Brou, L1
Deakyne, SJ1
Fairclough, DL1
Kempe, A1
Bajaj, L1
Seymour, CW1
Liu, VX1
Iwashyna, TJ1
Brunkhorst, FM1
Rea, TD1
Scherag, A1
Rubenfeld, G1
Kahn, JM1
Shankar-Hari, M1
Singer, M1
Deutschman, CS1
Escobar, GJ1
Angus, DC1
Schlegel, N1
Post, EH1
Su, F1
Hosokawa, K1
Taccone, FS1
Herpain, A1
Creteur, J1
Vincent, JL1
De Backer, D1
Swenson, KE1
Dziura, JD1
Aydin, A1
Reynolds, J1
Wira, CR1
McDonnell, NJ1
Paech, MJ1
Muchatuta, NA1
Hillyard, S1
Nathan, EA1
Ngan Kee, WD1
Khaw, KS1
Lau, TK1
Ng, FF1
Chui, K1
Ng, KL1
Noto, A1
Lentini, S1
Versaci, A1
Giardina, M1
Risitano, DC1
Messina, R1
David, A1
Cunha-Goncalves, D2
Perez-de-Sa, V2
Grins, E1
Dahm, PL1
Thörne, J2
Blomquist, S2
Larsson, A1
Strehlow, MC1
Ohashi, H1
Kawasaki, N1
Fujitani, S1
Kobayashi, K1
Ohashi, M1
Hosoyama, A1
Wada, T1
Taira, Y1
Salci, K1
Enblad, P1
Goiny, M1
Contant, CF1
Piper, I1
Nilsson, P1
Alders, DJ1
Groeneveld, AB1
Binsl, TW1
de Kanter, FJ1
van Beek, JH1
Fenhammar, J1
Rundgren, M1
Forestier, J1
Kalman, S1
Eriksson, S1
Frithiof, R1
Hiltunen, P1
Palve, J1
Setälä, L1
Mustonen, PK1
Berg, L1
Ruokonen, E2
Uusaro, A2
Kortepeter, MG1
Lawler, JV1
Honko, A1
Bray, M1
Johnson, JC1
Purcell, BK1
Olinger, GG1
Rivard, R1
Hepburn, MJ1
Hensley, LE1
Gómez, H1
Mesquida, J1
Hermus, L1
Polanco, P1
Kim, HK1
Zenker, S1
Torres, A1
Namas, R1
Vodovotz, Y1
Clermont, G1
Puyana, JC1
Pinsky, MR1
Blanié, A1
Vigué, B1
Benhamou, D1
Duranteau, J1
Geeraerts, T1
Nishibe, S1
Tsujita, M1
Hisamuddin, NA1
Azlan, K1
Saia, RS1
Bertozi, G1
Mestriner, FL1
Queiróz Cunha, F1
Cárnio, EC1
Lehtipalo, S1
Biber, B1
Fröjse, R1
Arnerlöv, C1
Johansson, G1
Winsö, O1
Glenn, TC1
Kelly, DF1
Boscardin, WJ1
McArthur, DL1
Vespa, P1
Oertel, M1
Hovda, DA1
Bergsneider, M1
Hillered, L1
Martin, NA1
Okudaira, S1
Suzuki, S1
Martikainen, TJ1
Tenhunen, JJ1
Leone, M2
Albanèse, J2
Delmas, A2
Chaabane, W1
Garnier, F2
Martin, C2
Erkinaro, T3
Mäkikallio, K3
Kavasmaa, T3
Alahuhta, S3
Räsänen, J3
Yokoyama, N1
Nishikawa, K1
Saito, Y1
Saito, S1
Goto, F1
Gumanenko, EK1
Nemchenko, NS1
Goncharov, AV1
Pashkovskiĭ, EV1
Bourgoin, A1
Haery, C1
Paladugu, B1
Symeoneides, S1
Taiberg, L1
Osman, J1
Trenholme, G1
Opal, SM1
Goldfarb, R1
Päkkilä, M2
Acharya, G2
Haugen, O1
Farstad, M1
Lise Kvalheim, V1
Rynning, SE1
Hammersborg, S1
Mongstad, A1
Husby, P1
Hurtado, FJ1
Nin, N1
Huhta, JC1
Morelli, A1
Lange, M1
Ertmer, C1
Broeking, K1
Van Aken, H1
Orecchioni, A1
Rocco, M1
Bachetoni, A1
Traber, DL1
Landoni, G1
Pietropaoli, P1
Westphal, M1
Ditting, T1
Hilgers, KF1
Stetter, A1
Linz, P1
Schönweiss, C1
Veelken, R1
Young, RS1
Yagel, SK1
Towfighi, J1
Aduen, J1
Bernstein, WK1
Khastgir, T1
Miller, J1
Kerzner, R1
Bhatiani, A1
Lustgarten, J1
Bassin, AS1
Davison, L1
Chernow, B1
Nimmo, GR1
Mackenzie, SJ1
Walker, S1
Nicol, M1
Grant, IS1
Mallard, EC1
Williams, CE1
Johnston, BM1
Gluckman, PD1
Joynt, G1
Doedens, L1
Lipman, J1
Bothma, P1
Zauner, A1
Doppenberg, E1
Soukup, J1
Menzel, M1
Young, HF1
Bullock, R1
Wray, GM1
Hinds, CJ1
Thiemermann, C1
Taylor, PM1
Glass, TF1
Fabian, MJ1
Schweitzer, JB1
Weinberg, JA1
Proctor, KG1
Hampl, H1
Berweck, S1
Ludat, K1
Fischer, HC1
Hertel, J1
Kuwagata, Y1
Oda, J1
Matsuyama, S1
Nishino, M1
Hashiguchi, N1
Ogura, H1
Tanaka, H1
Sugimoto, H1
McNeil, CJ1
Smith, LD1
Jenkins, LD1
York, MG1
Josephs, MJ1
DeMars, CS1
Hollister, K1
Tomassoni, A1
Himmelfarb, J1
Halperin, ML1
Mora, N1
Kaptanoglu, L1
Zhang, Z1
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Black, S1
Ver Steeg, K1
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Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
DPP3, Angiotensin II, and Renin Kinetics in Sepsis (DARK-Sepsis) Pilot: Serum Biomarkers to Predict Response to Angiotensin II vs. Standard-of-care Vasopressor Therapy in the Treatment of Septic Shock, a Randomized Controlled Pilot Trial[NCT05824767]Phase 440 participants (Anticipated)Interventional2023-04-17Recruiting
Effect of Personalized Hemodynamic Management Based on Serum Renin Concentration on Acute Kidney Injury Progression in Patients With Shock: a Randomized Controlled Trial.[NCT05898126]800 participants (Anticipated)Interventional2023-06-05Not yet recruiting
Comment Diminuer Les hémocultures Inutiles : Construction et Validation d'un Score prédictif de positivité Des hémocultures en réanimation.[NCT05686577]2,400 participants (Anticipated)Observational2022-11-22Recruiting
Early Efferon LPS Hemoperfusion Through Hypercrosslinked Styrene-divinylbenzene Copolymer With Immobilized LPS-selective Ligand for Treatment of Patients With Septic Shock[NCT04884854]9 participants (Actual)Observational2019-09-13Completed
The Correlation of Regional Cerebral Oxygen Saturation(rScO2) Variation in Passive Leg Raising (PLR) With Neurological Outcomes of Sepsis and Septic Shock Patients[NCT03523169]120 participants (Actual)Observational [Patient Registry]2016-12-31Completed
Evaluation of the PliNOSa® Test as an Aid in the Risk Assessment for the Onset of Sepsis[NCT01371929]166 participants (Actual)Observational2013-02-04Terminated (stopped due to NIH funding ended prior to full enrollment in the clinical study)
Impact of Intraoperative Goal-directed Blood Pressure Management and Dexmedetomidine on Outcomes of High-risk Patients After Major Abdominal Surgeries: a 2×2 Factorial Randomized Controlled Trial[NCT03933306]Phase 4496 participants (Actual)Interventional2019-05-20Active, not recruiting
La Sepsi Nel Paziente Anziano: Studio Prospettico Sui Pazienti Ricoverati in Ambiente Internistico.[NCT04945889]580 participants (Actual)Observational2019-04-01Completed
DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study)[NCT04624945]150 participants (Anticipated)Observational2020-11-25Recruiting
Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965]350 participants (Anticipated)Observational2018-08-15Active, not recruiting
Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia[NCT04401345]Phase 4258 participants (Actual)Interventional2020-06-01Completed
Comparison of Continuous Infusion of Noradrenaline Versus Phenylephrine During Cesarean Section Under Spinal Anesthesia. A Randomized Controlled Trial[NCT03842046]82 participants (Actual)Interventional2019-02-16Completed
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non-elective Caesarean Section: A Prospective Observational Study[NCT04692870]337 participants (Actual)Observational2021-01-06Completed
Effect of Vasopressin on Kidney and Cardiac Function in Previously Hypertensive Patients With Septic Shock: A Randomized Clinical Trial[NCT06125184]50 participants (Anticipated)Interventional2022-11-01Recruiting
EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock[NCT04134624]215 participants (Actual)Interventional2019-09-11Terminated (stopped due to Recruitment for this study was halted in February 2020 due to the COVID-19 pandemic. The study team was unable to continue enrollment due to decreased volumes (and the fact that COVID-19 mimics some of the signs and symptoms of severe sepsis))
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for lactic acid and Hypotension

ArticleYear
Predictors of Mortality in Acute Mesenteric Ischemia: A Systematic Review and Meta-Analysis.
    The Journal of surgical research, 2022, Volume: 275

    Topics: Arrhythmias, Cardiac; Creatinine; Female; Humans; Hypotension; Ischemia; Lactic Acid; Male; Mesenter

2022
What Inotrope and Why?
    Clinics in perinatology, 2020, Volume: 47, Issue:3

    Topics: Cardiac Output; Cardiotonic Agents; Dobutamine; Dopamine; Echocardiography; Epinephrine; Heart; Huma

2020
Identifying cardiogenic shock in the emergency department.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Acidosis, Lactic; Bradycardia; Confusion; Early Diagnosis; Echocardiography; Edema; Electrocardiogra

2020
Beyond Mean Arterial Pressure and Lactate: Perfusion End Points for Managing the Shocked Patient.
    Emergency medicine clinics of North America, 2019, Volume: 37, Issue:3

    Topics: Acute Kidney Injury; Arterial Pressure; Biomarkers; Blood Circulation; Carbon Dioxide; Cardiac Outpu

2019
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
    Aviation, space, and environmental medicine, 2013, Volume: 84, Issue:9

    Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion;

2013
[Initial resuscitation bundle and monitoring tissue perfusion in severe sepsis].
    Revista medica de Chile, 2013, Volume: 141, Issue:9

    Topics: Anti-Bacterial Agents; Chile; Humans; Hypotension; Intensive Care Units; Lactic Acid; Regional Blood

2013
[Updated definition of sepsis : Implications for diagnostics and therapy principles].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2017, Volume: 88, Issue:1

    Topics: Diagnosis, Differential; Fluid Therapy; Guideline Adherence; Humans; Hypotension; Lactic Acid; Sepsi

2017
Early identification of shock in critically ill patients.
    Emergency medicine clinics of North America, 2010, Volume: 28, Issue:1

    Topics: Acid-Base Imbalance; Blood Gas Monitoring, Transcutaneous; Emergency Service, Hospital; Humans; Hypo

2010
The role of bundles in sepsis care.
    Critical care clinics, 2006, Volume: 22, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Blood Glucose; Clinical Protocols; Critical Care; Dose

2006

Trials

10 trials available for lactic acid and Hypotension

ArticleYear
Effects of norepinephrine infusion during cardiopulmonary bypass on perioperative changes in lactic acid level (Norcal).
    Perfusion, 2023, Volume: 38, Issue:8

    Topics: Cardiopulmonary Bypass; Humans; Hyperlactatemia; Hypotension; Lactic Acid; Myocardial Ischemia; Nore

2023
A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise.
    International journal of obstetric anesthesia, 2018, Volume: 33

    Topics: Acidosis; Adult; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Ephedrine; Female; Fetal

2018
Indications for fluid resuscitation in patients with septic shock: Post-hoc analyses of the CLASSIC trial.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:3

    Topics: Aged; Conservative Treatment; Critical Care; Feasibility Studies; Female; Fluid Therapy; Humans; Hyp

2019
A randomised double-blind trial of phenylephrine and metaraminol infusions for prevention of hypotension during spinal and combined spinal-epidural anaesthesia for elective caesarean section.
    Anaesthesia, 2017, Volume: 72, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Ces

2017
Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.
    Anaesthesia, 2008, Volume: 63, Issue:12

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Carbon Dioxide; Cesarean Section

2008
Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.
    Anaesthesia, 2008, Volume: 63, Issue:12

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Carbon Dioxide; Cesarean Section

2008
Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.
    Anaesthesia, 2008, Volume: 63, Issue:12

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Carbon Dioxide; Cesarean Section

2008
Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.
    Anaesthesia, 2008, Volume: 63, Issue:12

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Carbon Dioxide; Cesarean Section

2008
Terlipressin in catecholamine-resistant septic shock patients.
    Shock (Augusta, Ga.), 2004, Volume: 22, Issue:4

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Blood Platelets; Drug Resistance; Epin

2004
[Comparison of the effects of colloid and crystalloid solution for volume preloading on maternal hemodynamics and neonatal outcome in spinal anesthesia for cesarean section].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:9

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Colloids; Crystalloid Solution

2004
Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Creatinine; Female; Humans; Hypertension; Hypotensio

2005
Glibenclamide dose response in patients with septic shock: effects on norepinephrine requirements, cardiopulmonary performance, and global oxygen transport.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:5

    Topics: Adenosine Triphosphate; Aged; Biological Transport; Blood Glucose; Catecholamines; Dose-Response Rel

2007
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism.
    The Journal of trauma, 2001, Volume: 50, Issue:6

    Topics: Analysis of Variance; Animals; Blood Gas Analysis; Blood Substitutes; Hemoglobins; Hemorrhage; Hydro

2001

Other Studies

78 other studies available for lactic acid and Hypotension

ArticleYear
Early postoperative hemodynamic instability after heart transplantation - incidence and metabolic indicators.
    BMC anesthesiology, 2021, 10-02, Volume: 21, Issue:1

    Topics: Biomarkers; Female; Heart Transplantation; Hemodynamics; Humans; Hypotension; Incidence; Lactic Acid

2021
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
Prospective analysis of intoxicated patients developing shock and/or organ failure.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Creatine; Cross-Sectional Studies; Female; Humans; Hypotension; Lac

2022
The Effect of Fluid Resuscitation Timing in Early Sepsis Resuscitation.
    Journal of intensive care medicine, 2023, Volume: 38, Issue:11

    Topics: Adult; Fluid Therapy; Humans; Hypotension; Lactic Acid; Resuscitation; Retrospective Studies; Sepsis

2023
Liver and skeletal muscle injury in a 12-year-old female patient after scoliosis correction in prone position: a case report.
    Spine deformity, 2020, Volume: 8, Issue:2

    Topics: Acidosis; Child; Evoked Potentials, Motor; Female; Humans; Hypotension; Iatrogenic Disease; Intraope

2020
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
    The Journal of surgical research, 2020, Volume: 253

    Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Dr

2020
Retrospective evaluation of the influence of azotemia on plasma lactate concentrations in hypotensive dogs and cats (2008-2018): 337 cases.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2020, Volume: 30, Issue:4

    Topics: Animals; Azotemia; Blood Pressure; Case-Control Studies; Cat Diseases; Cats; Creatinine; Dog Disease

2020
Lactate and hypotension as predictors of mortality after in-hospital cardiac arrest.
    Resuscitation, 2021, Volume: 158

    Topics: Adult; Cardiopulmonary Resuscitation; Hospitals; Humans; Hypotension; Lactic Acid; Out-of-Hospital C

2021
Central Administration of Angiotensin-(1-7) Improves Vasopressin Impairment and Hypotensive Response in Experimental Endotoxemia.
    Cells, 2021, 01-08, Volume: 10, Issue:1

    Topics: Angiotensin I; Animals; Endotoxemia; Gene Expression Regulation; Hypotension; Inflammation; Lactic A

2021
Defining Shock and Preshock for Mortality Risk Stratification in Cardiac Intensive Care Unit Patients.
    Circulation. Heart failure, 2021, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Arterial Pressure; Blood Pressure; Coronary Care Units; Creatinine; Female;

2021
High lactate is common, not alone a reason to stop resuscitation in IHCA.
    Resuscitation, 2021, Volume: 160

    Topics: Cardiopulmonary Resuscitation; Heart Arrest; Hospitals; Humans; Hypotension; Lactic Acid

2021
Reply to: High lactate is common, not alone a reason to stop resuscitation in IHCA.
    Resuscitation, 2021, Volume: 160

    Topics: Cardiopulmonary Resuscitation; Heart Arrest; Hospitals; Humans; Hypotension; Lactic Acid

2021
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
    Critical care medicine, 2022, 01-01, Volume: 50, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten

2022
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
    Critical care medicine, 2022, 01-01, Volume: 50, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten

2022
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
    Critical care medicine, 2022, 01-01, Volume: 50, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten

2022
Renin Kinetics Are Superior to Lactate Kinetics for Predicting In-Hospital Mortality in Hypotensive Critically Ill Patients.
    Critical care medicine, 2022, 01-01, Volume: 50, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypoten

2022
Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study.
    Critical care medicine, 2018, Volume: 46, Issue:4

    Topics: Aged; Anti-Bacterial Agents; APACHE; Blood Culture; Body Temperature; Comorbidity; Female; Heart Rat

2018
A fatal and metabolic experimental hemorrhagic shock in immature swine.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:12

    Topics: Animals; Biomarkers; Control Groups; Disease Models, Animal; Endpoint Determination; Hemodynamics; H

2017
Acute Hypotension After Moderate-Intensity Handgrip Exercise in Hypertensive Elderly People.
    Journal of strength and conditioning research, 2018, Volume: 32, Issue:10

    Topics: Aged; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Exercise; Female; Hand St

2018
Prognosis of patients excluded by the definition of septic shock based on their lactate levels after initial fluid resuscitation: a prospective multi-center observational study.
    Critical care (London, England), 2018, Feb-24, Volume: 22, Issue:1

    Topics: Aged; Chi-Square Distribution; Cohort Studies; Female; Fluid Therapy; Hospital Mortality; Humans; Hy

2018
SMFM Consult Series #47: Sepsis during pregnancy and the puerperium.
    American journal of obstetrics and gynecology, 2019, Volume: 220, Issue:4

    Topics: Anti-Bacterial Agents; Crystalloid Solutions; Culture Techniques; Delivery, Obstetric; Female; Fluid

2019
Target blood pressure for hypotensive resuscitation.
    Injury, 2013, Volume: 44, Issue:12

    Topics: Animals; Cytokines; Disease Models, Animal; Fluid Therapy; Hematocrit; Hypotension; Isotonic Solutio

2013
Implications of the new international sepsis guidelines for nursing care.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2013, Volume: 22, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Blood; Central Venous Pressure; Evidence-Based Nursing; Fluid Therapy;

2013
Early detection of gut ischemia-reperfusion injury during aortic abdominal aneurysmectomy: a pilot, observational study.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Aneurysm, Ruptured; Aortic Aneurysm, Abdominal; Carbon Dioxide; Colon; Constriction; Female; H

2013
Elevated lactate level and shock index in nontraumatic hypotensive patients presenting to the emergency department.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2015, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Emergency Service, Hospital; Female; History, Ancient; H

2015
The microcirculation is preserved in emergency department low-acuity sepsis patients without hypotension.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Flow Velocity; Case-Control Studies; Emergency Service, H

2014
Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Animals; Arterial Pressure; Biomarkers; Blood Gas Analysis; Blood Glucose; Bradycardia; Circadian Rh

2014
Association between hemodynamic presentation and outcome in sepsis patients.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:3

    Topics: Aged; Biomarkers; Blood Pressure; Chi-Square Distribution; Disease Progression; Emergency Service, H

2014
Safety, efficacy and response to a hydrocortisone rescue therapy protocol in children with refractory hypotension after cardiopulmonal bypass.
    Pediatric cardiology, 2015, Volume: 36, Issue:3

    Topics: Adolescent; Age Factors; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child, Preschoo

2015
Hemorrhagic hypotension-induced hypersensitivity of vagal pulmonary C-fibers to chemical stimulation and lung inflation in anesthetized rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Apr-01, Volume: 308, Issue:7

    Topics: Action Potentials; Animals; Arterial Pressure; Chemoreceptor Cells; Disease Models, Animal; Hemorrha

2015
Encephalopathy and high anion gap metabolic acidosis: an unusual herald of buried bumper syndrome.
    Lancet (London, England), 2015, Feb-21, Volume: 385, Issue:9969

    Topics: Acid-Base Equilibrium; Acidosis; Diagnosis, Differential; Humans; Hypotension; Hypothermia; Lactic A

2015
Disease heterogeneity and risk stratification in sepsis-related occult hypoperfusion: A retrospective cohort study.
    Journal of critical care, 2015, Volume: 30, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Emergency Service, Hospital; Female; Fluid Therapy;

2015
5-HT1A receptors of the nucleus tractus solitarii facilitate sympathetic recovery following hypotensive hemorrhage in rats.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-15, Volume: 309, Issue:2

    Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Disease Models, Animal; Hemorrhage; Hypotension;

2015
Arteriovenous blood gas agreement in intensive care patients with varying levels of circulatory compromise: a pilot study.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2015, Volume: 17, Issue:4

    Topics: Aged; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Cohort Studies; Critical Care; Cri

2015
Lactate Clearance and Normalization and Prolonged Organ Dysfunction in Pediatric Sepsis.
    The Journal of pediatrics, 2016, Volume: 170

    Topics: Biomarkers; Child; Cohort Studies; Emergency Service, Hospital; Humans; Hypotension; Lactic Acid; Mu

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
    JAMA, 2016, Feb-23, Volume: 315, Issue:8

    Topics: Adult; Consensus; Female; Hospital Mortality; Humans; Hypotension; Infections; Intensive Care Units;

2016
Changes in kidney perfusion and renal cortex metabolism in septic shock: an experimental study.
    The Journal of surgical research, 2017, Volume: 207

    Topics: Animals; Biomarkers; Female; Glucose; Hypotension; Kidney; Lactic Acid; Laser-Doppler Flowmetry; Pyr

2017
Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department.
    Internal and emergency medicine, 2018, Volume: 13, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Classification; Connecticut; Cross-Sectional Studies; Emergency Serv

2018
A retrospective analysis of terlipressin in bolus for the management of refractory vasoplegic hypotension after cardiac surgery.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:4

    Topics: Aged; Aged, 80 and over; Blood Pressure; Cardiac Output; Cardiac Surgical Procedures; Cardiopulmonar

2009
Inotropic support during experimental endotoxemic shock: part I. The effects of levosimendan on splanchnic perfusion.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy

2009
Inotropic support during experimental endotoxemic shock: part II. A comparison of levosimendan with dobutamine.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy

2009
Utility of microdialysis to detect the lactate/pyruvate ratio in subcutaneous tissue for the reliable monitoring of hemorrhagic shock.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2009, Volume: 45, Issue:6

    Topics: Animals; Blood Pressure; Early Diagnosis; Hypotension; Lactic Acid; Male; Microdialysis; Monitoring,

2009
Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat.
    Upsala journal of medical sciences, 2010, Volume: 115, Issue:4

    Topics: Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Glycerol; Hypotension; Hypoxant

2010
Endotoxemia decreases matching of regional blood flow and O2 delivery to O2 uptake in the porcine left ventricle.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4

    Topics: Animals; Cardiac Output; Coronary Circulation; Coronary Vessels; Endotoxemia; Endotoxins; Hypotensio

2011
Toll-like receptor 4 inhibitor TAK-242 attenuates acute kidney injury in endotoxemic sheep.
    Anesthesiology, 2011, Volume: 114, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cardiac Output; Creatinine; Disease Models, Anima

2011
The effects of hypotension and norepinephrine on microvascular flap perfusion.
    Journal of reconstructive microsurgery, 2011, Volume: 27, Issue:7

    Topics: Animals; Female; Glucose; Hypotension; Ischemia; Lactic Acid; Methyl Ethers; Microdialysis; Microsur

2011
Real-time monitoring of cardiovascular function in rhesus macaques infected with Zaire ebolavirus.
    The Journal of infectious diseases, 2011, Volume: 204 Suppl 3

    Topics: Acid-Base Equilibrium; Animals; Blood Gas Analysis; Blood Pressure; Blood Urea Nitrogen; Body Temper

2011
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated?
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cytokines; Disease Models, Animal

2012
The frontal lobe and thalamus have different sensitivities to hypoxia-hypotension after traumatic brain injury: a microdialysis study in rats.
    Journal of neurotrauma, 2012, Dec-10, Volume: 29, Issue:18

    Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Frontal Lob

2012
The impact of intraoperative vasopressin infusion in complex neonatal cardiac surgery.
    Interactive cardiovascular and thoracic surgery, 2012, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Urea Nitrogen; Cardiac Surgical

2012
The use of laboratory and physiological parameters in predicting mortality in sepsis induced hypotension and septic shock patients attending the emergency department.
    The Medical journal of Malaysia, 2012, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Biomarkers; Emergency Service, Hospital; Humans; Hypotension; Kaplan-Meier Estima

2012
Cardiovascular and inflammatory response to cholecystokinin during endotoxemic shock.
    Shock (Augusta, Ga.), 2013, Volume: 39, Issue:1

    Topics: Animals; Aorta; Blood Pressure; Cholecystokinin; Drug Evaluation, Preclinical; Endotoxemia; Heart Ra

2013
Does dopexamine influence regional vascular tone and oxygenation during intestinal hypotension?
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:10

    Topics: Animals; Dopamine; Female; Hemodynamics; Hypotension; Intestinal Mucosa; Intestines; Jejunum; Lactic

2002
Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose, and lactate metabolism.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:10

    Topics: Adult; Brain; Brain Injuries; Cerebrovascular Circulation; Cohort Studies; Energy Metabolism; Female

2003
Influence of spinal hypotension on fetal oxidative status during elective cesarean section in uncomplicated pregnancies.
    Archives of gynecology and obstetrics, 2005, Volume: 271, Issue:4

    Topics: Adult; Anesthesia, Spinal; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Cesarean Section; Fema

2005
Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cardiac Output; Dobutamine; Female; Fluid The

2004
Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model.
    British journal of anaesthesia, 2004, Volume: 93, Issue:6

    Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Ani

2004
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:6

    Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag

2004
The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.
    The Journal of infectious diseases, 2006, Jan-15, Volume: 193, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cardiac Output; Disease Models, Animal; Escherichia coli Infections;

2006
Ephedrine and phenylephrine for the treatment of maternal hypotension in a chronic sheep model of increased placental vascular resistance.
    British journal of anaesthesia, 2006, Volume: 96, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Animals; Disease Models, Animal; Ephedrine; Female; H

2006
Mean arterial pressure about 40 mmHg during CPB is associated with cerebral ischemia in piglets.
    Scandinavian cardiovascular journal : SCJ, 2006, Volume: 40, Issue:1

    Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation;

2006
Divergent effects of ephedrine and phenylephrine on cardiovascular hemodynamics of near-term fetal sheep exposed to hypoxemia and maternal hypotension.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Blood Pressure; Ca

2007
Renal sympathetic nerves modulate erythropoietin plasma levels after transient hemorrhage in rats.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Blood Pressure; Erythropoietin; Hemorrhage; Hypotension; Kidney; Kidney Diseases; Lactic Ac

2007
Systemic and neuropathologic effects of E. coli endotoxin in neonatal dogs.
    Pediatric research, 1983, Volume: 17, Issue:5

    Topics: Acidosis; Animals; Animals, Newborn; Brain; Dogs; Dose-Response Relationship, Drug; Endotoxins; Esch

1983
The use and clinical importance of a substrate-specific electrode for rapid determination of blood lactate concentrations.
    JAMA, 1994, Dec-07, Volume: 272, Issue:21

    Topics: Blood Chemical Analysis; Confidence Intervals; Critical Care; Critical Illness; Electrodes; Emergenc

1994
Acid-base responses to high-volume haemofiltration in the critically ill.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:9

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Hemofil

1993
Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Brain; Brain Edema; Carbon Dioxide; Co

1994
High-dose adrenaline with low systemic vascular resistance and symmetrical peripheral gangrene.
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 1996, Volume: 34, Issue:2

    Topics: Adult; Cardiac Output; Epinephrine; Gangrene; Humans; Hypotension; Lactic Acid; Malaria, Falciparum;

1996
Extended neuromonitoring: new therapeutic opportunities?
    Neurological research, 1998, Volume: 20 Suppl 1

    Topics: Adolescent; Adult; Body Temperature; Brain; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circula

1998
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
    Shock (Augusta, Ga.), 1998, Volume: 10, Issue:1

    Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne

1998
Adrenocortical and metabolic responses to dobutamine infusion during halothane anaesthesia in ponies.
    Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:4

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Blood Glucose; Blood Pressure; Dobutamine; Halothane;

1998
Secondary neurologic injury resulting from nonhypotensive hemorrhage combined with mild traumatic brain injury.
    Journal of neurotrauma, 1999, Volume: 16, Issue:9

    Topics: Animals; Blood Glucose; Brain Hemorrhage, Traumatic; Brain Injuries; Female; Hypotension; Intracrani

1999
How can hemodialysis-associated hypotension and dialysis-induced symptoms be explained and controlled--particularly in diabetic and arteriosclerotic patients?
    Clinical nephrology, 2000, Volume: 53, Issue:1 Suppl

    Topics: Arteriosclerosis; Diabetes Complications; Diabetes Mellitus; Electroencephalography; Humans; Hypoten

2000
Interleukin-1beta alters the oxygen delivery-oxygen consumption relationship in rabbits by increasing the slope of the supply-independent line.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Animals; Cardiac Tamponade; Female; Humans; Hypotension; Hypoxia; Interleukin-1; Lactic Acid; Models

2000
Citric acid ingestion: a life-threatening cause of metabolic acidosis.
    Annals of emergency medicine, 2001, Volume: 38, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Calcium; Calcium Chloride; Citric Acid; Critical Care; Drug

2001
Single vs. dual vessel porcine extracorporeal liver perfusion.
    The Journal of surgical research, 2002, Volume: 103, Issue:2

    Topics: Ammonia; Animals; Bile; Blood Pressure; Diuresis; Extracorporeal Circulation; Factor V; Female; Hear

2002
Dilation of coronary microvessels by adenosine induced hypotension in dogs.
    International journal of microcirculation, clinical and experimental, 1992, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Arterioles; Blood Gas Analysis; Coronary Circulation; Coronary Vessels; Dogs; Fe

1992
The effects of etomidate on cerebral metabolism and blood flow in a canine model for hypoperfusion.
    Journal of neurosurgery, 1991, Volume: 74, Issue:2

    Topics: Animals; Arteries; Blood Glucose; Blood Pressure; Brain; Cerebrovascular Circulation; Dogs; Etomidat

1991
Hormonal and metabolic effects of chronic interleukin-2 infusion in cancer patients.
    Journal of biological response modifiers, 1990, Volume: 9, Issue:2

    Topics: Adult; Carcinoma, Renal Cell; Epinephrine; Fatty Acids, Nonesterified; Female; Fever; Glycerol; Huma

1990
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:3

    Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extrace

1989
Preservation of cerebral metabolites by etomidate during incomplete cerebral ischemia in dogs.
    Anesthesiology, 1986, Volume: 65, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Dogs; Electroencephalography; Energy Metabolism; Et

1986
Severe self-poisoning with acebutolol in association with alcohol.
    Critical care medicine, 1987, Volume: 15, Issue:2

    Topics: Acebutolol; Adult; Alcoholic Intoxication; Combined Modality Therapy; Dopamine; Female; Heart Block;

1987