lactic acid has been researched along with Hypoplastic Left Heart Syndrome in 8 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gładki, M | 1 |
| Składzień, T | 1 |
| Żurek, R | 1 |
| Broniatowska, E | 1 |
| Wójcik, E | 1 |
| Skalski, JH | 1 |
| Mills, KI | 1 |
| Kaza, AK | 1 |
| Walsh, BK | 1 |
| Bond, HC | 1 |
| Ford, M | 1 |
| Wypij, D | 1 |
| Thiagarajan, RR | 1 |
| Almodovar, MC | 1 |
| Quinonez, LG | 1 |
| Baird, CW | 1 |
| Emani, SE | 1 |
| Pigula, FA | 1 |
| DiNardo, JA | 1 |
| Kheir, JN | 1 |
| Peterson, AL | 1 |
| Quartermain, MD | 1 |
| Ades, A | 1 |
| Khalek, N | 1 |
| Johnson, MP | 1 |
| Rychik, J | 1 |
| Murtuza, B | 1 |
| Wall, D | 1 |
| Reinhardt, Z | 1 |
| Stickley, J | 1 |
| Stumper, O | 1 |
| Jones, TJ | 1 |
| Barron, DJ | 1 |
| Brawn, WJ | 1 |
| Miyaji, K | 1 |
| Miyamoto, T | 1 |
| Kohira, S | 1 |
| Yoshii, T | 1 |
| Itatani, K | 1 |
| Sato, H | 1 |
| Inoue, N | 1 |
| Photiadis, J | 2 |
| Urban, AE | 2 |
| Sinzobahamvya, N | 2 |
| Fink, C | 2 |
| Schindler, E | 2 |
| Schneider, M | 2 |
| Marie Brecher, A | 1 |
| Asfour, B | 2 |
| Brecher, AM | 1 |
| Charpie, JR | 1 |
| Dekeon, MK | 1 |
| Goldberg, CS | 1 |
| Mosca, RS | 1 |
| Bove, EL | 1 |
| Kulik, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)[NCT02184169] | 27 participants (Actual) | Interventional | 2012-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A calculated estimate of cardiac index/systemic blood flow based on the Fick principle. (NCT02184169)
Timeframe: While mechanically ventilated, up to 14 days
| Intervention | L/min/m2 (Mean) |
|---|---|
| Hypoplastic Left Heart Syndrome | 1.3 |
| Transposition of the Great Arteries | 2.2 |
Oxygen consumption is the mass of oxygen gas consumed per minute, measured as the difference between oxygen mass inspired versus exhaled per minute. (NCT02184169)
Timeframe: While mechanically ventilated, up to 14 days
| Intervention | mL oxygen/min/m^2 (Mean) |
|---|---|
| HLHS | 72 |
| TGA With/Without VSD | 102 |
8 other studies available for lactic acid and Hypoplastic Left Heart Syndrome
| Article | Year |
|---|---|
Effect of acid-base balance on postoperative course in children with hypoplastic left heart syndrome after the modified Norwood procedure.
Topics: Acid-Base Equilibrium; Blood Gas Analysis; Female; Humans; Hypoplastic Left Heart Syndrome; Infant, | 2017 |
Phosphodiesterase Inhibitor-Based Vasodilation Improves Oxygen Delivery and Clinical Outcomes Following Stage 1 Palliation.
Topics: Blalock-Taussig Procedure; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Femal | 2016 |
Impact of mode of delivery on markers of perinatal hemodynamics in infants with hypoplastic left heart syndrome.
Topics: Apgar Score; Biomarkers; Blood Gas Analysis; Blood Glucose; Buffers; Carbon Dioxide; Cesarean Sectio | 2011 |
The importance of blood lactate clearance as a predictor of early mortality following the modified Norwood procedure.
Topics: Algorithms; Aorta; Biomarkers; Body Weight; Cardiopulmonary Bypass; Female; Follow-Up Studies; Human | 2011 |
The effectiveness of high-flow regional cerebral perfusion in Norwood stage I palliation.
Topics: Biomarkers; Cardiopulmonary Bypass; Cerebrovascular Circulation; Creatinine; Humans; Hypoplastic Lef | 2011 |
Restrictive left atrial outflow adversely affects outcome after the modified Norwood procedure.
Topics: Aortic Valve; Chi-Square Distribution; Heart Septal Defects, Atrial; Hemodynamics; Humans; Hypoplast | 2005 |
Optimal pulmonary to systemic blood flow ratio for best hemodynamic status and outcome early after Norwood operation.
Topics: Hemodynamics; Hospital Mortality; Humans; Hypoplastic Left Heart Syndrome; Infant; Infant, Newborn; | 2006 |
Postoperative hemodynamics after Norwood palliation for hypoplastic left heart syndrome.
Topics: Cardiac Surgical Procedures; Coronary Circulation; Extracorporeal Membrane Oxygenation; Hemodynamics | 2001 |