lactic acid has been researched along with Hypoglycemia in 240 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated that 6 weeks' administration of the SSRI fluoxetine can amplify a wide spectrum of ANS and metabolic counterregulatory responses during hypoglycemia in healthy individuals." | 9.13 | Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals. ( Briscoe, VJ; Davis, SN; Dawling, S; Ertl, AC; Tate, DB, 2008) |
| "Splenic rupture followed by lactic acidosis and hypoglycaemia should lead to suspicion of a cancer-mediated Warburg effect, and prompt urgent chemotherapy." | 8.31 | B-cell hepatosplenic lymphoma presenting in adult patient after spontaneous splenic rupture followed by severe persistent hypoglycaemia: type B lactic acidosis and acute liver failure. ( Gude, MF; Hamilton-Dutoit, S; Moen, M; Steiniche, T, 2023) |
| "Astrocytic glycogen serves as the major source of elevated lactate levels in the ventromedial hypothalamus (VMH) of animals exposed to recurring episodes of hypoglycemia." | 8.31 | Astrocyte Glycogen Is a Major Source of Hypothalamic Lactate in Rats With Recurrent Hypoglycemia. ( Chan, O; Chapman-Natewa, K; Farhat, R; Laxman, AK; Nelson, IE; Su, G, 2023) |
| "Type B lactic acidosis is a rare complication of non-tissue perfusion abnormalities caused by solid tumors or hematologic malignancies." | 8.12 | Type B lactic acidosis associated with diffuse large B-cell lymphoma and the Warburg effect. ( Lv, Z; Wang, C; Zhang, Y, 2022) |
| " Several patients with lactic acidosis and glucose levels below 1." | 7.80 | A patient with acute liver failure and extreme hypoglycaemia with lactic acidosis who was not in a coma: causes and consequences of lactate-protected hypoglycaemia. ( Gladden, LB; Goodwin, ML; McDonald, JR; Nijsten, MW; Oldenbeuving, G; Reijngoud, DJ; Sayilir, R, 2014) |
| "Literature review of cases of lymphoma with lactic acidosis, with and without hypoglycemia, demonstrated that these combinations occurred in multiple categories of B- and T-cell lymphoma." | 7.78 | "Hyper-warburgism," a cause of asymptomatic hypoglycemia with lactic acidosis in a patient with non-Hodgkin's lymphoma. ( Albert, SG; Elhomsy, GC; Eranki, V; Fesler, MJ; Griffing, GT; Michael, AG; Parker, SM, 2012) |
| " Insulin-induced hypoglycemia (IIH) promoted decreased responsiveness of hepatic glycogen catabolism to phenylephrine and isoproterenol, but not to glucagon and cyanide." | 7.70 | Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers. ( Bazotte, RB; Hell, NS; Lima, FB; Lopes, G; Vardanega, M, 1998) |
| "A hemodialysed patient with abdominal pain, severe lactic acidosis and prolonged hypoglycemia is described." | 7.69 | Acute necrotizing pancreatitis, lactic acidosis and prolonged hypoglycemia in a hemodialysed patient--a logical but unfortunately fatal combination. ( Chagnac, A; Gafter, U; Halperin, M; Korzets, A; Ori, Y; Weinstein, T; Zevin, D, 1996) |
| "Correlation between blood glucose, glucagon and adrenaline levels and gluconeogenesis was studied during the recovery from insulin-induced hypoglycemia in rats." | 7.69 | Insulin-induced hypoglycemia stimulates gluconeogenesis from 14C-lactate independently of glucagon and adrenaline releases in rats. ( Mokuda, O; Sakamoto, Y, 1994) |
| "This study demonstrated that 6 weeks' administration of the SSRI fluoxetine can amplify a wide spectrum of ANS and metabolic counterregulatory responses during hypoglycemia in healthy individuals." | 5.13 | Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals. ( Briscoe, VJ; Davis, SN; Dawling, S; Ertl, AC; Tate, DB, 2008) |
| "A review of the literature was performed, focusing on glucose and lactate in relation to cerebral energy metabolism, in the context of four typical clinical situations, namely (transient states of) low glucose availability for the brain due to hypoglycemia, combined with high blood lactate concentrations; permanent neuroglycopenia; lactic acidosis in mitochondrial disorders; and ischemic as well as traumatic brain injury." | 4.93 | Lactate and its many faces. ( Leen, WG; Taher, M; Wevers, RA; Willemsen, MA, 2016) |
| "Astrocytic glycogen serves as the major source of elevated lactate levels in the ventromedial hypothalamus (VMH) of animals exposed to recurring episodes of hypoglycemia." | 4.31 | Astrocyte Glycogen Is a Major Source of Hypothalamic Lactate in Rats With Recurrent Hypoglycemia. ( Chan, O; Chapman-Natewa, K; Farhat, R; Laxman, AK; Nelson, IE; Su, G, 2023) |
| "Splenic rupture followed by lactic acidosis and hypoglycaemia should lead to suspicion of a cancer-mediated Warburg effect, and prompt urgent chemotherapy." | 4.31 | B-cell hepatosplenic lymphoma presenting in adult patient after spontaneous splenic rupture followed by severe persistent hypoglycaemia: type B lactic acidosis and acute liver failure. ( Gude, MF; Hamilton-Dutoit, S; Moen, M; Steiniche, T, 2023) |
| "Type B lactic acidosis is a rare complication of non-tissue perfusion abnormalities caused by solid tumors or hematologic malignancies." | 4.12 | Type B lactic acidosis associated with diffuse large B-cell lymphoma and the Warburg effect. ( Lv, Z; Wang, C; Zhang, Y, 2022) |
| " Several patients with lactic acidosis and glucose levels below 1." | 3.80 | A patient with acute liver failure and extreme hypoglycaemia with lactic acidosis who was not in a coma: causes and consequences of lactate-protected hypoglycaemia. ( Gladden, LB; Goodwin, ML; McDonald, JR; Nijsten, MW; Oldenbeuving, G; Reijngoud, DJ; Sayilir, R, 2014) |
| " The disorder is manifested by the appearance of hypoglycaemia, ketosis and lactic acidosis (neonatally or later during fasting or induced by fructose) and may also be life-threatening." | 3.80 | Fructose-1,6-diphosphatase deficiency: a treatable neurometabolic disorder. ( Gowda, P; Jambagi, M; Kamate, M; Sonoli, S, 2014) |
| "Profound and prolonged hypoglycemia, normal or higher body temperature, and a low lactic acid level during hypoglycemia may be predictors of a poor outcome in patients with hypoglycemic encephalopathy." | 3.79 | Predictors of outcome in hypoglycemic encephalopathy. ( Fujita, N; Igarashi, S; Ikeda, T; Kanazawa, M; Kuwabara, T; Nishizawa, M; Sato, A; Shimohata, T; Takahashi, T; Tanaka, H, 2013) |
| "Literature review of cases of lymphoma with lactic acidosis, with and without hypoglycemia, demonstrated that these combinations occurred in multiple categories of B- and T-cell lymphoma." | 3.78 | "Hyper-warburgism," a cause of asymptomatic hypoglycemia with lactic acidosis in a patient with non-Hodgkin's lymphoma. ( Albert, SG; Elhomsy, GC; Eranki, V; Fesler, MJ; Griffing, GT; Michael, AG; Parker, SM, 2012) |
| " Plasma concentrations of lactate, beta-hydroxybutyrate, and glycerol were low and did not alter during hypoglycemia." | 3.77 | Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia. ( Battin, MR; Harding, JE; Harris, DL; Pleasants, AB; Spooner, CG; Weston, PJ; Williams, CE, 2011) |
| "The activities of glycogen phosphorylase and synthase during infusions of glucagon, isoproterenol, or cyanide in isolated liver of fed rats submitted to short-term insulin-induced hypoglycemia (IIH) was investigated." | 3.74 | Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats. ( Bazotte, RB; Curi, R; Lopes-Bertolini, G; Obici, S, 2008) |
| " At 14 days after tumor implantation, rats not supplemented displayed cancer cachexia characterized by loss of body weight, hypoglycemia, hyperlacticidemia, hypertriglyceridemia, decreased food intake and depletion of glycogen stores in the liver and skeletal muscles." | 3.74 | Effect of fish oil supplementation for 2 generations on changes in macrophage function induced by Walker 256 cancer cachexia in rats. ( Aikawa, J; Bonatto, SJ; Curi, R; Fernandes, LC; Folador, A; Hirabara, SM; Yamazaki, RK, 2007) |
| " Each study consisted of an equilibration (-140 to -40 min), a control (-40 to 0 min), and a test period (0 to 180 min), during which BAY R3401 (10 mg/kg), a glycogen phosphorylase inhibitor, was administered orally, either alone to create mild hypoglycemia or with peripheral glucose infusion to maintain euglycemia or create mild hyperglycemia." | 3.71 | Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog. ( Cherrington, AD; Emshwiller, MG; Flattem, N; Igawa, K; Neal, DW; Shiota, M, 2001) |
| "The purpose of the present study was to investigate the effect of the combined administration of hepatic gluconeogenic substrates (glycerol + L-lactate + L-alanine + L-glutamine) on glucose recovery during insulin induced hypoglycemia (IIH), in rats." | 3.71 | Combined administration of glucose precursors is more efficient than that of glucose itself in recovery from hypoglycemia. ( Bazotte, RB; Borba-Murad, GR; Curi, R; Galletto, R; Souza, HM, 2001) |
| " Thus, continuous parenteral infusion of glucose solution at an early stage after exposure may be an effective clinical therapy for the prevention of hypoglycaemia and metabolic lactic acidosis caused by MCA." | 3.71 | Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats. ( Dote, T; Furuya, E; Kato, J; Kono, K; Sakai, A; Shimizu, H; Toshina, Y; Usuda, K, 2002) |
| " Results show that, immediately after prolonged, moderate exercise, in relation to sedentary controls: 1) the glucose infusion rate required to maintain euglycemia, but not hypoglycemia, was higher; 2) R(d) was greater under euglycemic, but not hypoglycemic conditions; 3) NHGO, but not R(a), was suppressed more by a hyperinsulinemic euglycemic clamp, suggesting that hepatic glucose uptake was increased; 4) a decrement in glucose completely reversed the enhanced suppression of NHGO by insulin that followed exercise; and 5) arterial glucagon and cortisol were transiently higher in the presence of a decrement in glucose." | 3.71 | Prior exercise and the response to insulin-induced hypoglycemia in the dog. ( Coker, RH; Davis, SN; Galassetti, P; Koyama, Y; Lacy, DB; Pencek, RR; Wasserman, DH, 2002) |
| " Laboratory evaluation revealed hypoglycemia, hyperammonemia, lactic acidemia, hyperuricemia, and mild dicarboxylic aciduria." | 3.70 | Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle. ( Dorland, L; Duran, M; IJlst, L; Muntau, AC; Roscher, AA; Röschinger, W; Wanders, RJ, 2000) |
| " Insulin-induced hypoglycemia (IIH) promoted decreased responsiveness of hepatic glycogen catabolism to phenylephrine and isoproterenol, but not to glucagon and cyanide." | 3.70 | Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers. ( Bazotte, RB; Hell, NS; Lima, FB; Lopes, G; Vardanega, M, 1998) |
| " In addition, all tyrphostins and genistein attenuated the liver injury/failure, the pancreatic injury, the hypoglycaemia and the lactic acidosis caused by LPS." | 3.69 | Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase. ( Ruetten, H; Thiemermann, C, 1997) |
| "A hemodialysed patient with abdominal pain, severe lactic acidosis and prolonged hypoglycemia is described." | 3.69 | Acute necrotizing pancreatitis, lactic acidosis and prolonged hypoglycemia in a hemodialysed patient--a logical but unfortunately fatal combination. ( Chagnac, A; Gafter, U; Halperin, M; Korzets, A; Ori, Y; Weinstein, T; Zevin, D, 1996) |
| "Responses to insulin-induced hypoglycemia in fasted sham-operated (SHAM), adrenodemedullated (ADM), and epinephrine-infused ADM (ADM + E) rats were studied to ascertain the specific role of epinephrine in increasing resting skeletal muscle content of adenosine 3',5'-cyclic monophosphate (cAMP) and fructose 2,6-bisphosphate (F-2,6-P2), which are involved in stimulation of muscle glycogenolysis and lactate production." | 3.69 | Role of epinephrine during insulin-induced hypoglycemia in fasted rats. ( Chandler, SL; Huang, W; MacLean, PS; Mills, RH; Winder, WW, 1994) |
| "Correlation between blood glucose, glucagon and adrenaline levels and gluconeogenesis was studied during the recovery from insulin-induced hypoglycemia in rats." | 3.69 | Insulin-induced hypoglycemia stimulates gluconeogenesis from 14C-lactate independently of glucagon and adrenaline releases in rats. ( Mokuda, O; Sakamoto, Y, 1994) |
| "To examine the hypothesis that hypoglycemia has an adverse effect on brain energy state during seizure, neonatal dogs were subjected to bicuculline-induced seizure while hyperglycemic, normoglycemic, or hypoglycemic." | 3.67 | In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure. ( Briggs, RW; Cowan, BE; Dunham, SL; Novotny, E; Petroff, OA; Young, RS, 1987) |
| "Patients with deficient activity of hepatic glucose-6-phosphatase (glycogen storage disease type I [GSD-I]) have fasting-induced hypoglycemia, lactic acidemia, hyperuricemia, hyperlipidemia, and a markedly increased capacity for ethanol elimination." | 3.67 | Rapid ethanol elimination in patients with type I glycogen storage disease is an adaptive change resulting from recurrent hypoglycemia. ( Greene, HL; Hall, SD; Hoyumpa, AM; Parker, PH, 1986) |
| "Somatostatin (ST)-induced glucagon suppression results in hypoglycemia during rest and exercise." | 3.67 | Interactions between glucagon and other counterregulatory hormones during normoglycemic and hypoglycemic exercise in dogs. ( Lickley, HL; Vranic, M; Wasserman, DH, 1984) |
| "Adults with type 1 diabetes established on insulin pumps undertook HIIE and MIE stages in random order during automated insulin delivery via a closed-loop system (Medtronic)." | 2.84 | Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study. ( Gerche, A; Grosman, B; Horsburgh, JC; Jayawardene, DC; Jenkins, AJ; Kurtz, N; MacIsaac, RJ; McAuley, SA; O'Neal, DN; Roberts, TJ; Roy, A; Ward, GM, 2017) |
| "In the study, seven male subjects with type 1 diabetes injected their normal insulin dose and ate their usual breakfast." | 2.72 | The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes. ( Bussau, VA; Ferreira, LD; Fournier, PA; Jones, TW, 2006) |
| "0 mg/metformin (M) 400 mg combination with a G 2." | 2.71 | Effects of two different glibenclamide dose-strengths in the fixed combination with metformin in patients with poorly controlled T2DM: a double blind, prospective, randomised, cross-over clinical trial. ( Brunetti, P; Gori, M; Pagano, G; Perriello, G; Turco, C, 2004) |
| "Fatigue was postponed by carbohydrate feeding in 7 of the 10 subjects." | 2.65 | Carbohydrate feeding during prolonged strenuous exercise can delay fatigue. ( Coyle, EF; Ehsani, AA; Hagberg, JM; Holloszy, JO; Hurley, BF; Martin, WH, 1983) |
| "Glycogen metabolism has important implications for the functioning of the brain, especially the cooperation between astrocytes and neurons." | 2.52 | Energy Metabolism of the Brain, Including the Cooperation between Astrocytes and Neurons, Especially in the Context of Glycogen Metabolism. ( Baranowska-Bosiacka, I; Chlubek, D; Falkowska, A; Goschorska, M; Gutowska, I; Nowacki, P, 2015) |
| "Post mortem diagnosis of glucose metabolism disorders can be difficult and vague because of the lack of characteristic morphological findings." | 2.47 | Disorders of glucose metabolism-post mortem analyses in forensic cases: part I. ( Hess, C; Madea, B; Musshoff, F, 2011) |
| "Exercise is part of type 1 diabetes (T1D) management due to its cardiovascular and metabolic benefits." | 1.72 | Trends of glucose, lactate and ketones during anaerobic and aerobic exercise in subjects with type 1 diabetes: The ACTION-1 study. ( Braspenning, R; De Block, C; De Ridder, F; De Winter, B; Delbeke, D; Ledeganck, KJ; Pieralice, S; Pozzilli, P; Renard, E; Vissers, D, 2022) |
| "Nine people with type 1 diabetes and normal awareness of hypoglycemia underwent two hyperinsulinemic euglycemic-hypoglycemic (3." | 1.72 | Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes. ( de Galan, BE; Grandjean, J; Heerschap, A; Tack, CJ; van Asten, JJA; van der Graaf, M; van Meijel, LA; Wiegers, EC, 2022) |
| "In total, 189 children with type 1 diabetes from 11 diabetes care centers, in Poland, participated in a football tournament in 3 age categories: 7-9 (21." | 1.51 | Assessment of Safety and Glycemic Control During Football Tournament in Children and Adolescents With Type 1 Diabetes-Results of GoalDiab Study. ( Adamska, A; Araszkiewicz, A; Biegański, G; Domaszewska, K; Gawrecki, A; Jarosz-Chobot, P; Klupa, T; Konarski, J; Michalak, A; Naskręt, D; Skowrońska, B; Szadkowska, A; Szypowska, A; Zozulińska-Ziółkiewicz, D, 2019) |
| "Hypoglycemia is a common iatrogenic consequence of type 1 diabetes therapy that can lead to central nervous system injury and even death if untreated." | 1.51 | Hypothermic neuroprotection during reperfusion following exposure to aglycemia in central white matter is mediated by acidification. ( Brown, AM; Evans, RD; Ransom, BR; Rich, LR; Smith, PA, 2019) |
| "Treatment with carvedilol restored VMH lactate levels and improved the adrenaline (epinephrine) responses." | 1.51 | Carvedilol prevents counterregulatory failure and impaired hypoglycaemia awareness in non-diabetic recurrently hypoglycaemic rats. ( Chan, O; Farhat, R; Fisher, SJ; Knight, N; Sejling, AS; Su, G, 2019) |
| "Cerebral ischemia is a serious possible manifestation of diabetic vascular disease." | 1.48 | Acidosis mediates recurrent hypoglycemia-induced increase in ischemic brain injury in treated diabetic rats. ( Dave, KR; Perez-Pinzon, MA; Rehni, AK; Shukla, V, 2018) |
| "Glycogen storage disease type Ia is a genetic disorder that is associated with persistent fasting hypoglycemia and the inability to produce endogenous glucose." | 1.46 | Diabetes mellitus in a patient with glycogen storage disease type Ia: a case report. ( Cohn, A; Ohri, A, 2017) |
| "People with type 1 diabetes typically experience a decrease in blood glucose levels, particularly during low- and moderate-intensity exercises." | 1.46 | Atypical blood glucose response to continuous and interval exercise in a person with type 1 diabetes: a case report. ( Bracken, RM; Eckstein, ML; Groeschl, W; Hofmann, P; Koehler, G; Moser, O; Mueller, A; Pieber, TR; Tschakert, G, 2017) |
| "Age, active cancer, do-not-resuscitate status on ED arrival, lack of fever, hypoglycemia, and intubation were independently associated with increased in-hospital mortality." | 1.43 | Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department. ( Agarwal, A; Drumheller, BC; Gaieski, DF; Goyal, M; Mikkelsen, ME; Sante, SC; Weber, AL, 2016) |
| "Severe malaria is frequently managed without access to laboratory testing." | 1.40 | Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda. ( Conroy, AL; Hawkes, M; John, CC; Kain, KC; Liles, WC; Namasopo, S; Opoka, RO, 2014) |
| "Hypoglycemia is a common adverse event and can injure central nervous system (CNS) white matter (WM)." | 1.40 | Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage. ( Brown, AM; Chen, S; Evans, RD; Hamner, MA; Ransom, BR; Yang, X; Ye, ZC, 2014) |
| "Despite treatment, this syndrome complicated the interpretation of blood glucose readings as a measure of islet graft function and resulted in death or the need for euthanasia in all seven animals." | 1.38 | A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsis. ( Bottino, R; Cooper, DK; Dons, EM; Echeverri, GJ; Rigatti, LH; van der Windt, DJ; Wagner, R; Wijkstrom, M; Zhou, H, 2012) |
| "Hypoglycemia is common during development and is associated with the risk of neurodevelopmental deficits in human infants." | 1.36 | Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia. ( Ennis, K; Gruetter, R; Long, JD; Rao, R; Tkac, I; Ugurbil, K, 2010) |
| "For this purpose, a condition of hyperinsulinemia/hypoglycaemia was obtained with an intraperitoneal (ip) injection of regular insulin (1." | 1.35 | Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia. ( Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F, 2009) |
| "Nutritional interventions for intrauterine growth restriction (IUGR) have raised concerns for fetal toxicity, the mechanisms of which are unknown." | 1.35 | Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. ( Barry, JS; Brown, LD; Hay, WW; Limesand, SW; Rozance, PJ, 2009) |
| " To address this challenge, we evaluated the effect of prolonged gastrointestinal transit on the bioavailability of insulin carried by magnetically responsive microparticles in the presence of an external magnetic field." | 1.33 | Magnetically responsive polymeric microparticles for oral delivery of protein drugs. ( Cheng, J; Farokhzad, OC; Ho, D; Jeong, SY; Jon, S; Khademhosseini, A; Langer, RS; Sherifi, I; Teply, BA; Yim, CH, 2006) |
| "Babesiosis was diagnosed by examination of blood smears." | 1.33 | Glucose, lactate, and pyruvate concentrations in dogs with babesiosis. ( Jacobson, LS; Lobetti, RG, 2005) |
| "Providing glucose at 5 minutes after hypoxemia provided no benefits." | 1.32 | The contribution of glycolytic and oxidative pathways to retinal photoreceptor function. ( Bui, BV; Kalloniatis, M; Vingrys, AJ, 2003) |
| "Normoglycemic hyperinsulinemia caused no change in either retinal [3H]-radioactivity levels or [3H]-[R/VH] while decreasing retinal [14C]-radioactivity levels and retina to vitreous ratios of 14C-radioactivity levels." | 1.32 | Effects of insulin-induced acute hypoglycemia and normoglycemic hyperinsulinemia on the retinal uptake and ocular metabolism of glucose in rabbits. ( Amico, MC; Mattioli, F; Memoli, A; Muller, A; Romanelli, L; Savini, G, 2004) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| "Hyperlipidemia in Group 2 did not alter GU at any CPP, but maintained FAU at baseline levels until CPP was lowered to 40 mmHg." | 1.31 | Hyperlipidemia with hypoglycemia reduces myocardial oxygen utilization efficiency but not contractile function during coronary hypoperfusion. ( Bian, X; Downey, HF; Hart, BJ; Mallet, RT, 2000) |
| "A 10-month-old girl with glycogen storage disease type III developed recurrent severe hypoglycaemia induced by infectious mononucleosis." | 1.31 | Severe hypoglycaemia in a patient with glycogen storage disease type III induced by infectious mononucleosis. ( Hayasaka, K; Ikeda, H; Ito, A; Kato, M; Kimura, T; Okubo, M, 2001) |
| "Fatigue was assessed every 10 min using the Borg scale for rating of perceived exertion." | 1.30 | Well-being, cerebral function, and physical fatigue after nocturnal hypoglycemia in IDDM. ( King, P; Kong, MF; Macdonald, IA; Parkin, H; Tattersall, RB, 1998) |
| "The optimal dichloroacetate pharmacokinetic model for both subjects with cirrhosis and control subjects had two compartments, with all parameters weight normalized." | 1.30 | Pharmacokinetics and pharmacodynamics of dichloroacetate in patients with cirrhosis. ( Fisher, DM; Shangraw, RE, 1999) |
| "We conclude that DAN, long IDDM duration per se, and antecedent recent hypoglycemia contribute to different extents to impaired adrenaline responses and hypoglycemia unawareness." | 1.30 | Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation. ( Bolli, GB; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Di Vincenzo, A; Fanelli, C; Lalli, C; Lepore, M; Pampanelli, S; Porcellati, F, 1997) |
| "From 1981 to 1994, 112 IDDM patients were on IT." | 1.29 | Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia. ( Annibale, B; Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lalli, C; Lepore, M; Modarelli, F; Pampanelli, S; Rambotti, AM; Sindaco, PD, 1996) |
| "This fasting hypoglycemia was completely reversed by giving oral medium-chain fatty acids (MCT)." | 1.27 | Effects of medium-chain triglyceride feeding on glucose homeostasis in the newborn rat. ( Ferre, P; Girard, J; Leturque, A; Pegorier, JP; Turlan, P, 1983) |
| "Intrauterine growth retardation was induced in newborn dogs after 3 days of maternal nutritional deprivation (birth weight 251 +/- 7 versus 227 +/- 7 g, p less than 0." | 1.27 | Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs. ( Kliegman, RM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (19.58) | 18.7374 |
| 1990's | 44 (18.33) | 18.2507 |
| 2000's | 66 (27.50) | 29.6817 |
| 2010's | 67 (27.92) | 24.3611 |
| 2020's | 16 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Watha, K | 1 |
| Davenport, A | 1 |
| Tangvoraphonkchai, K | 1 |
| Wang, C | 1 |
| Lv, Z | 1 |
| Zhang, Y | 1 |
| van Gemert, LA | 1 |
| de Galan, BE | 5 |
| Wevers, RA | 2 |
| Ter Heine, R | 1 |
| Willemsen, MA | 2 |
| van Meijel, LA | 1 |
| van Asten, JJA | 1 |
| Grandjean, J | 1 |
| Heerschap, A | 2 |
| Tack, CJ | 4 |
| van der Graaf, M | 3 |
| Wiegers, EC | 3 |
| Ali, MH | 2 |
| Alshamrani, AA | 1 |
| Briski, KP | 8 |
| De Ridder, F | 1 |
| Ledeganck, KJ | 1 |
| De Winter, B | 1 |
| Braspenning, R | 1 |
| Delbeke, D | 1 |
| Renard, E | 1 |
| Pozzilli, P | 1 |
| Pieralice, S | 1 |
| Vissers, D | 1 |
| De Block, C | 1 |
| van de Sande, MJA | 1 |
| Lopriore, E | 1 |
| Verweij, EJT | 1 |
| de Bruin, C | 1 |
| Slaghekke, F | 1 |
| Tollenaar, LSA | 1 |
| Galderisi, A | 2 |
| Tordin, M | 2 |
| Suppiej, A | 2 |
| Cainelli, E | 2 |
| Baraldi, E | 2 |
| Trevisanuto, D | 2 |
| Napit, PR | 1 |
| Mahmood, ASMH | 1 |
| Ibrahim, MMH | 1 |
| Su, G | 2 |
| Farhat, R | 3 |
| Laxman, AK | 1 |
| Chapman-Natewa, K | 1 |
| Nelson, IE | 1 |
| Chan, O | 5 |
| Young, GM | 1 |
| Jacobs, PG | 1 |
| Tyler, NS | 1 |
| Nguyen, TP | 1 |
| Castle, JR | 1 |
| Wilson, LM | 1 |
| Branigan, D | 1 |
| Gabo, V | 1 |
| Guillot, FH | 1 |
| Riddell, MC | 1 |
| El Youssef, J | 1 |
| Moen, M | 1 |
| Hamilton-Dutoit, S | 1 |
| Steiniche, T | 1 |
| Gude, MF | 1 |
| Richter, J | 1 |
| Rabe, D | 1 |
| Duysen, K | 1 |
| Melchert, UH | 1 |
| Oltmanns, KM | 2 |
| Morrow, B | 1 |
| Malkoc, A | 1 |
| Gong, T | 1 |
| Probst, D | 1 |
| Lin, C | 1 |
| Sen, A | 1 |
| La Belle, JT | 1 |
| Sejling, AS | 2 |
| Wang, P | 2 |
| Zhu, W | 3 |
| Knight, N | 2 |
| Appadurai, D | 1 |
| Harris, DL | 3 |
| Weston, PJ | 3 |
| Harding, JE | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Lactate Administration on Cerebral Blood Flow During Hypoglycemia; Are the Suppressive Effects of Lactate on Counterregulatory Responses to Hypoglycemia Reflected in an Altered CBF Response?[NCT03730909] | 10 participants (Anticipated) | Interventional | 2018-06-11 | Recruiting | |||
| cArdiopulmonary exerCise Test Assessing Multiple bIOmarkers iN Type 1 Diabetes[NCT05097339] | 21 participants (Actual) | Observational [Patient Registry] | 2019-05-10 | Completed | |||
| The Effect of Exercise-induced Hyperlacticacidemia on Counterregulatory Responses, Symptoms, Cognitive Function and Brain Lactate Accumulation During Hypoglycemia in (Hypoglycemic Unaware)Type I Diabetes Patients and Normal Controls[NCT02308293] | 30 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Exercise and Blood Glucose Levels in Patients With Type I Diabetes - a Pilot Study[NCT02075567] | 7 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| The Effect of Insulin-induced Hypoglycemia on Brain Lactate Accumulation and Regional Cerebral Blood Flow in Patients With Type 1 Diabetes Mellitus With and Without Hypoglycemia Unawareness and Non-diabetic Controls[NCT02146404] | 21 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| The Effect of Intravenous Lactate Administration on Brain Lactate Concentrations and pH During Euglycemia and Hypoglycemia in Patients With Type 1 Diabetes With and Without Impaired Awareness of Hypoglycemia[NCT03286816] | 19 participants (Actual) | Interventional | 2016-11-30 | Completed | |||
| Metabolic Studies in Type 1 Diabetic Patients After Allogenic Intraportal Islet Transplantation.[NCT01668485] | Phase 4 | 36 participants (Actual) | Interventional | 2001-11-30 | Completed | ||
| Restoration of Hypoglycemia Awareness With Metoclopramide[NCT03970720] | Phase 2 | 36 participants (Anticipated) | Interventional | 2019-05-28 | Recruiting | ||
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| Prevention of Hypoglycemia After Exercise Using DreaMed Substance Administration Device in Children and Adolescents With Type 1 Diabetes (The PHYSI-DREAM Study)[NCT02657083] | 20 participants (Actual) | Interventional | 2016-01-31 | Completed | |||
| Day and Night Closed-Loop Glycemic Control With Faster-Acting Insulin Aspart in Young Adults With Type 1 Diabetes Using DreaMed Glucositter - The Fast PHYSI-DREAM Study[NCT03212950] | 20 participants (Actual) | Interventional | 2017-07-10 | Completed | |||
| Exercise-related Fuel Metabolism and Glucose Stability in Individuals With Type 1 Diabetes Mellitus[NCT02068638] | 27 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
| Propranolol as a Treatment for Impaired Awareness of Hypoglycemia in Type 1 Diabetes[NCT03161964] | Phase 2 | 2 participants (Actual) | Interventional | 2017-10-19 | Terminated (stopped due to Statistical power could not be achieved due to low enrollment.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for lactic acid and Hypoglycemia
| Article | Year |
|---|---|
Lactate infusion as therapeutical intervention: a scoping review.
Topics: Adult; Brain Injuries, Traumatic; Child; Humans; Hypoglycemia; Lactic Acid; Sodium Lactate; Waste Pr | 2022 |
Lactate and its many faces.
Topics: Acidosis, Lactic; Brain Chemistry; Child; Energy Metabolism; Glucose; Humans; Hypoglycemia; Lactic A | 2016 |
Energy Metabolism of the Brain, Including the Cooperation between Astrocytes and Neurons, Especially in the Context of Glycogen Metabolism.
Topics: Animals; Astrocytes; Biological Transport; Brain; Cerebrovascular Circulation; Citric Acid Cycle; Di | 2015 |
Disorders of glucose metabolism-post mortem analyses in forensic cases: part I.
Topics: Blood Proteins; Diabetes Mellitus; Diabetic Ketoacidosis; Forensic Pathology; Fructosamine; Glucose; | 2011 |
Effect of dietary interventions in the maintenance of normoglycaemia in glycogen storage disease type 1a: a systematic review and meta-analysis.
Topics: Blood Glucose; Cholesterol; Dietary Carbohydrates; Glucose; Glycogen Storage Disease Type I; Humans; | 2013 |
Hypoglycemia and white matter: pathophysiology of axon injury and role of glycogen.
Topics: Action Potentials; Animals; Astrocytes; Axons; Brain; Glucose; Glycogen; Humans; Hypoglycemia; Lacti | 2002 |
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D | 1983 |
Cell damage in the brain: a speculative synthesis.
Topics: Acidosis; Animals; Biological Transport, Active; Brain Ischemia; Calcium; Cell Membrane; Cerebrovasc | 1981 |
The biological basis of malarial disease.
Topics: Animals; Carbohydrate Metabolism; Cytokines; Humans; Hypoglycemia; Immune Tolerance; Inflammation Me | 1997 |
Mitochondrial respiratory chain disorders and the liver.
Topics: Diffuse Cerebral Sclerosis of Schilder; DNA, Mitochondrial; Electron Transport; Humans; Hypoglycemia | 1999 |
On the diagnosis of hypoglycemia in car drivers--including a review of the literature.
Topics: Accidents, Traffic; Adult; Automobile Driving; Blood Glucose; Case-Control Studies; Ethanol; Female; | 2001 |
Glucose homeostasis and the kidney.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose; Glycogen; | 1992 |
The acyl-CoA dehydrogenation deficiencies. Recent advances in the enzymic characterization and understanding of the metabolic and pathophysiological disturbances in patients with acyl-CoA dehydrogenation deficiencies.
Topics: Acidosis; Acyl Coenzyme A; Acyl-CoA Dehydrogenase, Long-Chain; Ammonia; Carboxylic Acids; Chemical P | 1985 |
24 trials available for lactic acid and Hypoglycemia
| Article | Year |
|---|---|
Lactate infusion increases brain energy content during euglycemia but not hypoglycemia in healthy men.
Topics: Adenosine Triphosphate; Blood Glucose; Brain; C-Peptide; Energy Metabolism; Hormones; Humans; Hydrog | 2019 |
A Single Bout of High-Intensity Interval Training Reduces Awareness of Subsequent Hypoglycemia in Patients With Type 1 Diabetes.
Topics: Adult; Awareness; Case-Control Studies; Catecholamines; Cognitive Dysfunction; Cross-Over Studies; D | 2017 |
Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study.
Topics: Adult; Biomarkers; Blood Glucose; Combined Modality Therapy; Cross-Over Studies; Diabetes Mellitus, | 2017 |
Magnitude and mechanisms of glucose counterregulation following islet transplantation in patients with type 1 diabetes suffering from severe hypoglycaemic episodes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Gluconeogenesis; Glucose; Glucose Clamp Tec | 2014 |
Simulated games activity vs continuous running exercise: a novel comparison of the glycemic and metabolic responses in T1DM patients.
Topics: Adult; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Therapy; Female; Games, Recrea | 2015 |
Lactate, rather than ketones, may provide alternative cerebral fuel in hypoglycaemic newborns.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Birth Weight; Blood Glucose; Breast Feeding; Double-Blind Method; | 2015 |
Accuracy of Continuous Glucose Monitoring (CGM) during Continuous and High-Intensity Interval Exercise in Patients with Type 1 Diabetes Mellitus.
Topics: Adult; Bicycling; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 1; Diet, Diabeti | 2016 |
Effects of a selective serotonin reuptake inhibitor, fluoxetine, on counterregulatory responses to hypoglycemia in healthy individuals.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Autonomic Nervous System; Blood Glucose; Blood Pressure; Fatt | 2008 |
Continuous glucose monitoring reveals delayed nocturnal hypoglycemia after intermittent high-intensity exercise in nontrained patients with type 1 diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Energy Metabolism; Exercise; He | 2010 |
Lactate infusion during euglycemia but not hypoglycemia reduces subsequent food intake in healthy men.
Topics: Adult; Anorexia; Appetite; Eating; Energy Intake; Fasting; Feeding Behavior; Humans; Hypoglycemia; I | 2012 |
Effects of two different glibenclamide dose-strengths in the fixed combination with metformin in patients with poorly controlled T2DM: a double blind, prospective, randomised, cross-over clinical trial.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dou | 2004 |
Effect of differing antecedent hypoglycemia on counterregulatory responses to exercise in type 1 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty Acids, Nonesterified; | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
The 10-s maximal sprint: a novel approach to counter an exercise-mediated fall in glycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Exercise Test; F | 2006 |
Sleep loss alters basal metabolic hormone secretion and modulates the dynamic counterregulatory response to hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Adult; C-Peptide; Cross-Over Studies; Epinephrin | 2007 |
Different brain responses to hypoglycemia induced by equipotent doses of the long-acting insulin analog detemir and human regular insulin in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Brain; C-Peptide; Dose-Response Relationship, | 2008 |
Carbohydrate feeding during prolonged strenuous exercise can delay fatigue.
Topics: Adult; Blood Glucose; Dietary Carbohydrates; Epinephrine; Exercise Test; Fatigue; Fatty Acids, Nones | 1983 |
Beta-adrenoceptor blockade and recovery from hypoglycaemia in diabetic subjects: normalization after lactate and glycerol infusions.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Epinephrine; Female; Gluconeogenesis; Glycerol; Growth Horm | 1982 |
Protection by lactate of cerebral function during hypoglycaemia.
Topics: Adult; Blood Chemical Analysis; Brain; Brain Diseases; Cognition; Hormones; Humans; Hypoglycemia; La | 1994 |
Effect of hyperketonemia and hyperlacticacidemia on symptoms, cognitive dysfunction, and counterregulatory hormone responses during hypoglycemia in normal humans.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Cognition; Female; Hormones; Humans; Hydroxybutyrates; | 1994 |
Intravenous lactate prevents cerebral dysfunction during hypoglycaemia in insulin-dependent diabetes mellitus.
Topics: Adult; Analysis of Variance; Brain; Diabetes Mellitus, Type 1; Epinephrine; Evoked Potentials, Audit | 1998 |
Differential gender responses to hypoglycemia are due to alterations in CNS drive and not glycemic thresholds.
Topics: Adult; Blood Glucose; Body Mass Index; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Gl | 2000 |
Alcohol and glucose counterregulation during acute insulin-induced hypoglycemia in type 2 diabetic subjects.
Topics: Acute Disease; Blood Glucose; Central Nervous System Depressants; Diabetes Mellitus, Type 2; Ethanol | 2001 |
Effects of morning hypoglycemia on neuroendocrine and metabolic responses to subsequent afternoon hypoglycemia in normal man.
Topics: Adult; Blood Glucose; Calorimetry, Indirect; Catecholamines; Female; Glucagon; Hemodynamics; Humans; | 2001 |
Systemic and local adrenergic regulation of muscle glucose utilization during hypoglycemia in healthy subjects.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Arteries; Blood Flow Velocity; Blo | 2002 |
203 other studies available for lactic acid and Hypoglycemia
| Article | Year |
|---|---|
Changes in blood glucose and lactate concentrations with hemodialysis.
Topics: Aged; Blood Glucose; Diabetes Mellitus; Female; Glucose; Hemodialysis Solutions; Humans; Hypoglycemi | 2022 |
Type B lactic acidosis associated with diffuse large B-cell lymphoma and the Warburg effect.
Topics: Acidosis, Lactic; Adult; Humans; Hypoglycemia; Lactic Acid; Lymphoma, Large B-Cell, Diffuse; Male; P | 2022 |
Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes.
Topics: Cerebrovascular Circulation; Diabetes Mellitus, Type 1; Glucose Clamp Technique; Humans; Hypoglycemi | 2022 |
Hindbrain lactate regulation of hypoglycemia-associated patterns of catecholamine and metabolic-sensory biomarker gene expression in A2 noradrenergic neurons innervating the male versus female ventromedial hypothalamic nucleus.
Topics: Adrenergic Neurons; Animals; Biomarkers; Catecholamines; Female; Gene Expression; Hypoglycemia; Lact | 2022 |
Trends of glucose, lactate and ketones during anaerobic and aerobic exercise in subjects with type 1 diabetes: The ACTION-1 study.
Topics: Adult; Anaerobiosis; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Exerci | 2022 |
Lactate acidosis and hypoglycaemia in twin anaemia polycythemia sequence donors.
Topics: Female; Fetofetal Transfusion; Humans; Hypoglycemia; Lactic Acid; Placenta; Polycythemia; Pregnancy; | 2023 |
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study.
Topics: Glucose; Humans; Hyperglycemia; Hypoglycemia; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; | 2023 |
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study.
Topics: Glucose; Humans; Hyperglycemia; Hypoglycemia; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; | 2023 |
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study.
Topics: Glucose; Humans; Hyperglycemia; Hypoglycemia; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; | 2023 |
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study.
Topics: Glucose; Humans; Hyperglycemia; Hypoglycemia; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; | 2023 |
Sex-dimorphic hindbrain lactate regulation of ventromedial hypothalamic nucleus glucoregulatory neuron 5'-AMP-activated protein kinase activity and transmitter marker protein expression.
Topics: Adrenergic Neurons; AMP-Activated Protein Kinases; Animals; Female; Glucose; Hypoglycemia; Hypoglyce | 2023 |
Astrocyte Glycogen Is a Major Source of Hypothalamic Lactate in Rats With Recurrent Hypoglycemia.
Topics: Animals; Astrocytes; Glycogen; Glycogen Phosphorylase; Hypoglycemia; Hypothalamus; Lactic Acid; Rats | 2023 |
Quantifying insulin-mediated and noninsulin-mediated changes in glucose dynamics during resistance exercise in type 1 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Glucose; Humans; Hypoglycemia; Insulin; Lactic A | 2023 |
B-cell hepatosplenic lymphoma presenting in adult patient after spontaneous splenic rupture followed by severe persistent hypoglycaemia: type B lactic acidosis and acute liver failure.
Topics: Acidosis, Lactic; Adult; Humans; Hypoglycemia; Lactic Acid; Liver Failure, Acute; Lymphoma, Non-Hodg | 2023 |
Development of Electrochemical Methods to Enzymatically Detect Lactate and Glucose Using Imaginary Impedance for Enhanced Management of Glycemic Compromised Patients.
Topics: Algorithms; Biomarkers; Biosensing Techniques; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 2019 |
Repeated Activation of Noradrenergic Receptors in the Ventromedial Hypothalamus Suppresses the Response to Hypoglycemia.
Topics: Adrenergic Agonists; Adrenergic Neurons; Animals; Blood Glucose; Down-Regulation; Epinephrine; Gluco | 2021 |
Alternative Cerebral Fuels in the First Five Days in Healthy Term Infants: The Glucose in Well Babies (GLOW) Study.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Blood Glucose; Brain; Female; Humans; Hypoglycemia; Infant, Newbo | 2021 |
Exhaustive endurance exercise activates brain glycogen breakdown and lactate production more than insulin-induced hypoglycemia.
Topics: Animals; Blood Glucose; Brain; Cyclic AMP; Disease Models, Animal; Glycogen; Hypoglycemia; Insulin; | 2021 |
Sudden Unexpected Death in a Child From Acute Myeloid Leukemia.
Topics: Acidosis; Anemia; Child, Preschool; Death, Sudden; Female; Gene Rearrangement; Histone-Lysine N-Meth | 2021 |
On-line plasma lactate concentration monitoring in critically ill patients.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Central Venous Catheters; Critical Illness; Female; Glucose | 2017 |
Atypical blood glucose response to continuous and interval exercise in a person with type 1 diabetes: a case report.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Exercise Test; Gl | 2017 |
Poly((D,L)lactic-glycolic)acid-star glucose nanoparticles for glucose transporter and hypoglycemia-mediated tumor targeting.
Topics: Animals; Antineoplastic Agents; Carbocyanines; Cell Line; Docetaxel; Drug Delivery Systems; Drug Lib | 2017 |
Diabetes mellitus in a patient with glycogen storage disease type Ia: a case report.
Topics: Acarbose; Adult; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobi | 2017 |
Acidosis mediates recurrent hypoglycemia-induced increase in ischemic brain injury in treated diabetic rats.
Topics: Acidosis; Acrylamides; Animals; Brain Ischemia; CA1 Region, Hippocampal; Central Nervous System Agen | 2018 |
Performance during a strenuous swimming session is associated with high blood lactate: pyruvate ratio and hypoglycemia in fasted rats.
Topics: Animals; Blood Glucose; Fasting; Hypoglycemia; Lactic Acid; Liver; Male; Perfusion; Physical Conditi | 2018 |
Carvedilol prevents counterregulatory failure and impaired hypoglycaemia awareness in non-diabetic recurrently hypoglycaemic rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Blood Glucose; Body Weight; Carvedilol; Catheteriza | 2019 |
Hypothermic neuroprotection during reperfusion following exposure to aglycemia in central white matter is mediated by acidification.
Topics: Animals; Axons; Disease Models, Animal; Evoked Potentials; Glucose; Hydrogen-Ion Concentration; Hypo | 2019 |
Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus.
Topics: Animals; Carbon Radioisotopes; Catecholamines; Coumaric Acids; gamma-Aminobutyric Acid; Glucose; Glu | 2019 |
Assessment of Safety and Glycemic Control During Football Tournament in Children and Adolescents With Type 1 Diabetes-Results of GoalDiab Study.
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Humans; Hypoglycemia; Hypoglyce | 2019 |
Recurrent hypoglycemia: boosting the brain's metabolic flexibility.
Topics: Animals; Humans; Hypoglycemia; Lactic Acid; Male; Neurons | 2013 |
Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia.
Topics: Animals; Blood Glucose; Brain; Dose-Response Relationship, Drug; Electrophysiology; Glucose; Glucose | 2013 |
Diabetes: Does lactate sustain brain metabolism during hypoglycaemia?
Topics: Animals; Brain; Diabetes Mellitus; Glucose; Humans; Hypoglycemia; Lactates; Lactic Acid; Rats | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.
Topics: Adult; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid; Oxidation-Reduction | 2013 |
Fat and carbohydrate metabolism during exercise in phosphoglucomutase type 1 deficiency.
Topics: Adult; Bicycling; Carbohydrate Metabolism; Exercise Test; Exercise Tolerance; Glucose; Glycogen Stor | 2013 |
Predictors of outcome in hypoglycemic encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Body Temperature; Brain Diseases, Metabolic; Female; | 2013 |
Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.
Topics: Animals; Bicuculline; Coumaric Acids; Diabetes Mellitus, Experimental; Diazoxide; GABA Antagonists; | 2013 |
The diabetic brain during hypoglycemia: in the midst of plenty of lactate.
Topics: Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Lactic Acid | 2013 |
Continuous glucose monitoring in children with glycogen storage disease type I.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Child; Child, Preschoo | 2014 |
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Di | 2014 |
Lactate and the mechanism of hypoglycemia-associated autonomic failure in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hypoglycemia; Lactic Acid; Male; | 2013 |
Hindbrain lactostasis regulates hypothalamic AMPK activity and metabolic neurotransmitter mRNA and protein responses to hypoglycemia.
Topics: Adrenergic Neurons; AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Energy Metabolis | 2014 |
Hindbrain energy status controls hypothalamic metabolic and neuropeptide signals. Focus on "Hindbrain lactostasis regulates hypothalamic AMPK activity and hypothalamic metabolic neurotransmitter mRNA and protein responses to hypoglycemia".
Topics: AMP-Activated Protein Kinases; Animals; Energy Metabolism; Hypoglycemia; Hypothalamus; Lactic Acid; | 2014 |
Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda.
Topics: Anemia; Blood Glucose; Child; Child, Preschool; Cohort Studies; Female; Health Resources; Hemoglobin | 2014 |
A patient with acute liver failure and extreme hypoglycaemia with lactic acidosis who was not in a coma: causes and consequences of lactate-protected hypoglycaemia.
Topics: Acetaminophen; Acidosis, Lactic; Analgesics, Non-Narcotic; Blood Glucose; Follow-Up Studies; Humans; | 2014 |
Endurance training increases brain lactate uptake during hypoglycemia by up regulation of brain lactate transporters.
Topics: Animals; Biological Transport; Cerebral Cortex; Diabetes Mellitus, Experimental; Gene Expression; Hi | 2014 |
Fructose-1,6-diphosphatase deficiency: a treatable neurometabolic disorder.
Topics: Acidosis, Lactic; Child, Preschool; Female; Fructose-1,6-Diphosphatase Deficiency; Humans; Hypoglyce | 2014 |
Lactate, glucose and the neonatal brain: it's time to challenge the paradigm.
Topics: Female; Humans; Hypoglycemia; Ketones; Lactic Acid; Male; Pregnancy | 2015 |
Age-related metabolic fatigue during low glucose conditions in rat hippocampus.
Topics: Aging; Animals; CA1 Region, Hippocampal; Glucose; Glycogen; Hypoglycemia; In Vitro Techniques; Lacti | 2015 |
Hindbrain lactate regulates preoptic gonadotropin-releasing hormone (GnRH) neuron GnRH-I protein but not AMPK responses to hypoglycemia in the steroid-primed ovariectomized female rat.
Topics: Adrenergic Neurons; AMP-Activated Protein Kinases; Animals; Blood Glucose; Drug Administration Route | 2015 |
Altered Plasticity of Glycogen Phosphorylase in Forebrain Gliosomes Obtained from Insulinoma Patients.
Topics: Adenosine Triphosphate; Aged; Astrocytes; Case-Control Studies; Cyclic AMP-Dependent Protein Kinases | 2015 |
Response of lactate metabolism in brain glucosensing areas of rainbow trout (Oncorhynchus mykiss) to changes in glucose levels.
Topics: Adaptation, Physiological; Animals; Astrocytes; Brain; Energy Metabolism; Enzymes; Fish Proteins; Ge | 2015 |
Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department.
Topics: Academic Medical Centers; Adult; Age Factors; Aged; Aged, 80 and over; Blood Coagulation Disorders; | 2016 |
Effect of Exercise Intensity on Glucose Requirements to Maintain Euglycemia During Exercise in Type 1 Diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet; Exercise; Female; Glucose; Glucos | 2016 |
Defective hepatic bicarbonate production due to carbonic anhydrase VA deficiency leads to early-onset life-threatening metabolic crisis.
Topics: Acidosis; Adolescent; Bicarbonates; Carbonic Anhydrases; Child; Child, Preschool; Humans; Hyperammon | 2016 |
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech | 2016 |
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech | 2016 |
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech | 2016 |
Brain Lactate Concentration Falls in Response to Hypoglycemia in Patients With Type 1 Diabetes and Impaired Awareness of Hypoglycemia.
Topics: Adult; Awareness; Brain; Case-Control Studies; Diabetes Mellitus, Type 1; Female; Glucose Clamp Tech | 2016 |
Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.
Topics: Animals; Blood Glucose; Brain; Diabetes Mellitus, Type 1; Disease Models, Animal; Dogs; Female; Fruc | 2016 |
Uncovering molecular abnormalities leading to the Warburg effect in primary refractory diffuse large B-cell lymphoma.
Topics: Acidosis, Lactic; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Drug | 2016 |
Proinflammatory Effects of Hypoglycemia in Humans With or Without Diabetes.
Topics: Adult; Awareness; Case-Control Studies; Chemokine CCL2; Cytokines; Diabetes Mellitus, Type 1; Epinep | 2017 |
Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction.
Topics: Acidosis; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Disease Models, Animal; Down-Regulati | 2009 |
Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats.
Topics: Animals; Enzyme Activation; Feeding Behavior; Glucagon; Glucose; Glycogen Phosphorylase; Glycogen Sy | 2008 |
Evaluation of parenteral depot insulin formulation using PLGA and PLA microparticles.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Carriers; Drug Delivery Systems; Female; Humans; Hypo | 2009 |
Severe hypoglycemia associated with an illegal sexual enhancement product adulterated with glibenclamide: MR imaging findings.
Topics: Adult; Aged; Blood Volume; Brain; Cerebrovascular Disorders; Coma; Consciousness Disorders; Diffusio | 2009 |
The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep.
Topics: Adrenocorticotropic Hormone; Animals; Blood Gas Analysis; Blood Glucose; Cardiovascular System; Cate | 2009 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglyce | 2009 |
In situ coexpression of glucose and monocarboxylate transporter mRNAs in metabolic-sensitive caudal dorsal vagal complex catecholaminergic neurons: transcriptional reactivity to insulin-induced hypoglycemia and caudal hindbrain glucose or lactate repletio
Topics: Animals; ATP-Binding Cassette Transporters; Catecholamines; Chemoreceptor Cells; Energy Metabolism; | 2009 |
Thioredoxin binding protein-2 inhibits excessive fetal hypoglycemia during maternal starvation by suppressing insulin secretion in mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Carrier Proteins; Disease Models | 2010 |
A case of glycogen storage disease type Ib presenting with prolonged neonatal hypoglycaemia and minimal metabolic abnormalities.
Topics: Antiporters; Diagnosis, Differential; Glucose; Glycogen Storage Disease Type I; Humans; Hypoglycemia | 2010 |
Effects of poly (lactic-co-glycolic acid) as a co-emulsifier on the preparation and hypoglycaemic activity of insulin-loaded solid lipid nanoparticles.
Topics: Analysis of Variance; Animals; Blood Glucose; Castor Oil; Chemical Phenomena; Diabetes Mellitus, Exp | 2009 |
Systemic glucose and brain energy metabolism after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Brain; Critical Care; Energy Metaboli | 2010 |
Metabolic crisis after traumatic brain injury is associated with a novel microdialysis proteome.
Topics: Blood Glucose; Brain; Brain Injuries; Brain Ischemia; Cerebral Hemorrhage, Traumatic; Energy Metabol | 2010 |
Effect of insulin hypoglycemia on brain glucose, glycogen, lactate and phosphates.
Topics: Brain; Glucose; Glycogen; Humans; Hypoglycemia; Insulin; Lactates; Lactic Acid; Phosphates | 1947 |
Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia.
Topics: Animals; Animals, Newborn; Brain Chemistry; Chronic Disease; Energy Metabolism; Glucose; Glutamic Ac | 2010 |
Effects of fasting on hypoxic ventilatory responses and the contribution of histamine H1 receptors in mice.
Topics: Animals; Basal Metabolism; Blood Glucose; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Hy | 2011 |
Participation of the liver gluconeogenesis in the glibenclamide-induced hypoglycaemia in rats.
Topics: Animals; Gluconeogenesis; Glucose; Glyburide; Humans; Hypoglycemia; Lactic Acid; Liver; Male; Pyruvi | 2011 |
Estimation of intracellular fluxes in cerebellar neurons after hypoglycemia: importance of the pyruvate recycling pathway and glutamine oxidation.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Glucose; Glutamic Acid; Glutamine; Glycolysi | 2011 |
Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Electroencephalography; Glucose Oxidase; Glycerol; Humans; Hyp | 2011 |
Comparative effects of short-term and long-term insulin-induced hypoglycemia on glucose production in the perfused livers of weaned rats.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; | 2011 |
Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Cell Death; Diabetic Neuropathies; Electrocardiograp | 2012 |
Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids.
Topics: Animals; Fatty Acids; Ghrelin; Gluconeogenesis; Hypoglycemia; Lactic Acid; Male; Mice; Mice, Inbred | 2012 |
"Hyper-warburgism," a cause of asymptomatic hypoglycemia with lactic acidosis in a patient with non-Hodgkin's lymphoma.
Topics: Acidosis, Lactic; Asymptomatic Diseases; Female; Glucose; Glycolysis; Humans; Hypoglycemia; Lactic A | 2012 |
A syndrome of severe hypoglycemia and acidosis in young immunosuppressed diabetic monkeys and pigs-association with sepsis.
Topics: Acidosis; Animals; Bacteria; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; | 2012 |
Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.
Topics: Alanine; Animals; Blood Glucose; Consciousness; Dihydropyridines; Dogs; Fasting; Fatty Acids, Nonest | 2002 |
Correlation between blood glucose concentration and glucose concentration in subcutaneous adipose tissue evaluated with microdialysis during intensive care.
Topics: Adipose Tissue; Blood Glucose; Brain Injuries; Critical Care; Energy Metabolism; Glycerol; Humans; H | 2002 |
Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation.
Topics: Animals; Blood Glucose; Epinephrine; Glucagon; Glucose; Homeostasis; Hypoglycemia; Hypothalamus, Mid | 2003 |
Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephri | 2003 |
Combined administration of glucose precursors is more efficient than that of glucose itself in recovery from hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Drug Combinations; Glucose; Glycerol; Hypoglycemia; Lactic Acid; Li | 2001 |
The contribution of glycolytic and oxidative pathways to retinal photoreceptor function.
Topics: Aerobiosis; Anaerobiosis; Animals; Dark Adaptation; Drug Combinations; Electroretinography; Glucose; | 2003 |
Blood glucose responses and incidence of hypoglycaemia in elite tennis under practice and tournament conditions.
Topics: Adult; Blood Glucose; Germany; Homeostasis; Humans; Hypoglycemia; Incidence; Lactic Acid; Male; Phys | 2003 |
Cerebrolysin inhibits lipid peroxidation induced by insulin hypoglycemia in the brain and heart of mice.
Topics: Amino Acids; Animals; Blood Glucose; Blood Proteins; Brain Chemistry; Heart; Hypoglycemia; Hypoglyce | 2003 |
Effect of thermal stress and muscular exercise, with and without insulin hypoglycaemia, on the body temperature, perspiration rate, and electrolyte and lactate content of sweat.
Topics: Body Temperature; Electrolytes; Exercise; Hot Temperature; Hypoglycemia; Insulins; Lactates; Lactic | 1954 |
[Lactic acid content in chick embryo muscles in the condition of insulin hypoglycemia].
Topics: Animals; Chick Embryo; Humans; Hypoglycemia; Insulin; Lactates; Lactic Acid; Muscles | 1962 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
LPS-induced changes in myocardial markers in neonatal rats.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Biomarkers; Blood Glucose; Energy Metabolism; Fat | 2003 |
[Mechanism of alloxan hypoglycemia; disturbance of liver glycogenesis from lactic acid].
Topics: Alloxan; Blood Glucose; Hypoglycemia; Lactic Acid; Liver | 1950 |
Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.
Topics: Adult; Alanine; Blood Glucose; Cognition Disorders; Glucose Clamp Technique; Hormones; Humans; Hypog | 2004 |
Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats.
Topics: Acetates; Acidosis, Lactic; Animals; Blood Glucose; Glucose; Hypoglycemia; Infusions, Intravenous; L | 2002 |
Effects of insulin-induced acute hypoglycemia and normoglycemic hyperinsulinemia on the retinal uptake and ocular metabolism of glucose in rabbits.
Topics: Animals; Biotransformation; Blood Glucose; Choroid; Deoxyglucose; Eye; Glucose; Glucose Clamp Techni | 2004 |
Obesity-prone rats have preexisting defects in their counterregulatory response to insulin-induced hypoglycemia.
Topics: Adipose Tissue; Animals; Arcuate Nucleus of Hypothalamus; Blood Glucose; Body Composition; Catechola | 2004 |
Glycolysis regulates the induction of lactate utilization for synaptic potentials after hypoxia in the granule cell of guinea pig hippocampus.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Cell Hypoxia; | 2004 |
Plasma catecholamines and the counterregulatory responses to hypoglycemia in infants: a critical role for epinephrine and cortisol.
Topics: Case-Control Studies; Cohort Studies; Epinephrine; Female; Food Deprivation; Humans; Hydrocortisone; | 2004 |
Diagnostic values of combined glucose and lactate values in cerebrospinal fluid and vitreous humour--our experiences.
Topics: Cerebrospinal Fluid; Drug Overdose; Forensic Medicine; Glucose; Glycated Hemoglobin; Humans; Hypogly | 2004 |
A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother.
Topics: Adipose Tissue; Antiretroviral Therapy, Highly Active; Arginine; Asphyxia; Brain; Cardiomegaly; Card | 2005 |
Intermittent high-intensity exercise does not increase the risk of early postexercise hypoglycemia in individuals with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise; Humans; Hypoglycemia; Insulin | 2005 |
Glucose, lactate, and pyruvate concentrations in dogs with babesiosis.
Topics: Acid-Base Equilibrium; Animals; Babesiosis; Blood Gas Analysis; Blood Glucose; Blood Pressure Determ | 2005 |
Cortical Fluoro-Jade staining and blunted adrenomedullary response to hypoglycemia after noncoma hypoglycemia in rats.
Topics: Adrenal Medulla; Animals; Autonomic Nervous System; Biomarkers; Blood Glucose; Cerebral Cortex; Cons | 2005 |
Brain oxygen utilization is unchanged by hypoglycemia in normal humans: lactate, alanine, and leucine uptake are not sufficient to offset energy deficit.
Topics: Adult; Alanine; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Female; Glucos | 2006 |
A potential important role of skeletal muscle in human counterregulation of hypoglycemia.
Topics: Adult; Alanine; Blood Glucose; Female; Forearm; Gluconeogenesis; Glucose; Glycogenolysis; Humans; Hy | 2005 |
Magnetically responsive polymeric microparticles for oral delivery of protein drugs.
Topics: Administration, Oral; Animals; Blood Glucose; Delayed-Action Preparations; Drug Carriers; Electromag | 2006 |
Interaction of carbohydrate metabolism and rat liquid gastric emptying in sustained running.
Topics: Animals; Carbohydrate Metabolism; Gastric Emptying; Hypoglycemia; Lactic Acid; Male; Models, Animal; | 2006 |
Effect of fish oil supplementation for 2 generations on changes in macrophage function induced by Walker 256 cancer cachexia in rats.
Topics: Animals; Blood Glucose; Body Weight; Cachexia; Carcinoma 256, Walker; Coconut Oil; Eating; Fatty Aci | 2007 |
Caudal hindbrain lactate infusion alters glucokinase, SUR1, and neuronal substrate fuel transporter gene expression in the dorsal vagal complex, lateral hypothalamic area, and ventromedial nucleus hypothalamus of hypoglycemic male rats.
Topics: Animals; ATP-Binding Cassette Transporters; Brain; Energy Metabolism; Gene Expression Regulation; Gl | 2007 |
Effects of caudal hindbrain lactate infusion on insulin-induced hypoglycemia and neuronal substrate transporter glucokinase and sulfonylurea receptor-1 gene expression in the ovariectomized female rat dorsal vagal complex: Impact of estradiol.
Topics: Animals; ATP-Binding Cassette Transporters; Drug Implants; Estradiol; Estrogens; Female; Fourth Vent | 2008 |
Effects of caudal fourth ventricular lactate infusion on hypoglycemia-associated MCT2, GLUT3, GLUT4, GCK, and sulfonylurea receptor-1 gene expression in the ovariectomized female rat LHA and VMH: impact of estradiol.
Topics: Animals; ATP-Binding Cassette Transporters; Estradiol; Female; Fourth Ventricle; Glucokinase; Glucos | 2008 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag | 1983 |
Interactions between glucagon and other counterregulatory hormones during normoglycemic and hypoglycemic exercise in dogs.
Topics: Animals; Blood Glucose; Catecholamines; Dogs; Drug Interactions; Fatty Acids, Nonesterified; Female; | 1984 |
Autonomic neural control mechanisms of substrate and hormonal responses to acute hypoglycaemia in man.
Topics: Adrenergic Fibers; Adult; Blood Glucose; Cholinergic Fibers; Cyclic AMP; Fatty Acids, Nonesterified; | 1981 |
Lactate reverses insulin-induced hypoglycemic stupor in suckling-weanling mice: biochemical correlates in blood, liver, and brain.
Topics: Animals; Animals, Suckling; Bicarbonates; Brain; Energy Metabolism; Hydrogen-Ion Concentration; Hypo | 1983 |
Severe hypoglycemia and hyperinsulinemia in falciparum malaria.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Brain Diseases; C-Peptide; Child; | 1983 |
Systemic and neuropathologic effects of E. coli endotoxin in neonatal dogs.
Topics: Acidosis; Animals; Animals, Newborn; Brain; Dogs; Dose-Response Relationship, Drug; Endotoxins; Esch | 1983 |
Differential diagnosis of hypoglycemia in children by responses to fasting and 2-deoxyglucose.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Deoxy Sug | 1983 |
Exdotoxin-induced metabolic changes in the conscious, unrestrained rat: hypoglycemia and elevated blood lactate concentrations without hyperinsulinemia.
Topics: Animals; Blood Glucose; Endotoxins; Hyperinsulinism; Hypoglycemia; Insulin; Lactates; Lactic Acid; M | 1981 |
The development of glucose metabolism in infants of diabetic mothers.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Female; Fetal Blood; Gluc | 1984 |
Lactate as a cerebral metabolic fuel for glucose-6-phosphatase deficient children.
Topics: Brain; Child; Child, Preschool; Glucose; Glycogen Storage Disease Type I; Humans; Hypoglycemia; Lact | 1984 |
Postnatal hypoglycaemia and gluconeogenesis in the newborn rat. Delayed onset of gluconeogenesis in prematurely delivered newborns.
Topics: Animals; Animals, Newborn; Blood Glucose; Female; Gluconeogenesis; Hypoglycemia; Kidney; Lactates; L | 1983 |
Absence of exercise-induced hypoglycaemia in type i (insulin-dependent) diabetic patients during maintenance of normoglycaemia by short-term, open-loop insulin infusion.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon | 1982 |
Effects of medium-chain triglyceride feeding on glucose homeostasis in the newborn rat.
Topics: Animals; Animals, Newborn; Blood Glucose; Carbon Radioisotopes; Dietary Fats; Homeostasis; Hypoglyce | 1983 |
Endotoxin dose. II. Effects on glucose biokinetics in Yucatan minipigs.
Topics: Animals; Blood Glucose; Endotoxins; Female; Hyperglycemia; Hypoglycemia; Kinetics; Lactates; Lactic | 1983 |
[Unusual concomitant associations in sepsis].
Topics: Acidosis; Aged; Disseminated Intravascular Coagulation; Humans; Hypoglycemia; Inappropriate ADH Synd | 1983 |
Regionally selective metabolic effects of hypoglycemia in brain.
Topics: Adenosine Triphosphate; Animals; Brain; Electroencephalography; Fructosediphosphates; Glucose; Gluco | 1981 |
The post mortem diagnosis of fatal hypoglycaemia using the fatty liver and kidney syndrome of chicks as a model.
Topics: Animals; Biotin; Blood Glucose; Chickens; Fatty Liver; Glucose; Hypoglycemia; Kidney Diseases; Lacta | 1982 |
Blood-brain barrier permeability to lactic acid in the newborn dog: lactate as a cerebral metabolic fuel.
Topics: Animals; Animals, Newborn; Blood Glucose; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; D | 1982 |
Factors affecting tryptophan-induced hypoglycaemia in rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hormones; Hypoglyc | 1982 |
Effect of hepatic vagotomy on plasma catecholamines during exercise-induced hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Catecholamines; Epinephrine; Fatty Acids, Nonesterifi | 1995 |
Glucose, lactate, insulin, and somatostatin responses to endotoxin in developing rats.
Topics: Age Factors; Animals; Bacterial Toxins; Blood Glucose; Disease Models, Animal; Endotoxins; Female; H | 1994 |
Studies on metabolic regulation using NMR spectroscopy.
Topics: Animals; Brain; Calcium; Energy Metabolism; Glucose; Glutamic Acid; Glycerophosphates; Guinea Pigs; | 1993 |
Insulin-induced hypoglycemia stimulates gluconeogenesis from 14C-lactate independently of glucagon and adrenaline releases in rats.
Topics: Animals; Blood Glucose; Carbon Radioisotopes; Epinephrine; Glucagon; Gluconeogenesis; Hypoglycemia; | 1994 |
Paradoxical insulin-induced increase in gluconeogenesis in response to prolonged hypoglycemia in conscious dogs.
Topics: Animals; Arteries; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Gluconeogenesis; Glucose; | 1995 |
Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Awareness; Blood Glucose; Diabetes Mellitus, Type 1; Epine | 1994 |
Role of epinephrine during insulin-induced hypoglycemia in fasted rats.
Topics: Adrenal Medulla; Animals; Blood Glucose; Body Weight; Cyclic GMP; Epinephrine; Fasting; Glycogen; Hy | 1994 |
Effects of hypo- and hyperglycemia on brain energy metabolites in mice exposed to carbon monoxide.
Topics: Animals; Brain; Carbon Monoxide Poisoning; Energy Metabolism; Glucose; Hyperglycemia; Hypoglycemia; | 1994 |
Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Atropine; Autonomic Nervous System; Awareness; Blood Glucose; | 1993 |
Response to intravenous injections of amylin and glucagon in fasted, fed, and hypoglycemic rats.
Topics: Amyloid; Animals; Blood Glucose; Eating; Fasting; Glucagon; Hypoglycemia; Injections, Intravenous; I | 1993 |
Exogenous substrate uptake by fetal lambs during reduced glucose delivery.
Topics: Amines; Animals; Biological Availability; Blood Glucose; Female; Fetal Blood; Fetus; Gestational Age | 1993 |
Metabolic adaptation in small for gestational age infants.
Topics: Adaptation, Physiological; Blood Glucose; Enteral Nutrition; Fatty Acids, Nonesterified; Female; Hum | 1993 |
Dexamethasone attenuates hypoglycemia in ten day old rats treated with TNF alpha.
Topics: Animals; Blood Glucose; Dexamethasone; Drug Interactions; Female; Glucocorticoids; Glucose Transport | 1996 |
Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty | 1996 |
Acute necrotizing pancreatitis, lactic acidosis and prolonged hypoglycemia in a hemodialysed patient--a logical but unfortunately fatal combination.
Topics: Acidosis, Lactic; Blood Gas Analysis; Blood Glucose; Diabetes Mellitus, Type 2; Fatal Outcome; Femal | 1996 |
Galactosamine alters glucose regulation in ten-day-old rats treated with a low dose of endotoxin.
Topics: Adipose Tissue; Animals; Bacterial Toxins; Blood Glucose; Brain Chemistry; Endotoxins; Enterotoxins; | 1996 |
Mouse embryonic cardiac metabolism under euglycemic and hypoglycemic conditions.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Carbon Dioxide; Female; Glycolysis; Heart; Hypoglyce | 1996 |
In the absence of counterregulatory hormones, the increase in hepatic glucose production during insulin-induced hypoglycemia in the dog is initiated in the liver rather than the brain.
Topics: Adrenalectomy; Alanine; Animals; Blood Glucose; Brain; Dogs; Fatty Acids, Nonesterified; Female; Glu | 1996 |
The effect of intravenous lactate on cerebral function during hypoglycaemia.
Topics: Adult; Blood Glucose; Brain; Catecholamines; Evoked Potentials, Auditory; Evoked Potentials, Auditor | 1997 |
Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; | 1997 |
Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase.
Topics: Acidosis, Lactic; Animals; Cells, Cultured; Cyclooxygenase 2; Endotoxemia; Endotoxins; Enzyme Induct | 1997 |
Neonatal lethal mitochondrial trifunctional protein deficiency mimicking a respiratory chain defect.
Topics: Ammonia; Cardiomyopathy, Dilated; Electron Transport; Fatal Outcome; Female; Humans; Hypoglycemia; I | 1997 |
[U-13C]glutamate metabolism in astrocytes during hypoglycemia and hypoxia.
Topics: Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cell Hypoxia; Cells, Cultured; Glucose; Glutami | 1998 |
Responsiveness of glycogen catabolism to adrenergic agonists during insulin-induced hypoglycemia in rat livers.
Topics: Adrenergic Agonists; Animals; Area Under Curve; Cyanides; Gastrointestinal Agents; Glucagon; Glucose | 1998 |
Hormonal counterregulation failure in rats is related to previous hyperglycaemia-hyperinsulinaemia.
Topics: Animals; Blood Glucose; Body Weight; Catecholamines; Eating; Female; Glucagon; Glycerol; Hyperglycem | 1998 |
Well-being, cerebral function, and physical fatigue after nocturnal hypoglycemia in IDDM.
Topics: Activities of Daily Living; Adult; Affect; Blood Glucose; Brain; Catecholamines; Circadian Rhythm; D | 1998 |
Cerebral metabolic response to hypoglycemia in severe intrauterine growth-retarded rat pups.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Brain; Female; Fetal Growth Retardation; Glucose; Hy | 1998 |
Renal lactate metabolism and gluconeogenesis during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Flow Velocity; Blood Glucose; Dogs; Epinephrine; Gluconeogenesis; Glucose; G | 1998 |
Cerebral metabolic response to hypoglycemia in severe intrauterine growth-retarded rat pups.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Fetal Growth Retardation; Glucose; Hypoglycemia; Lac | 1998 |
Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose; Hormones; Humans; Hyperinsulin | 1999 |
Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method.
Topics: Anesthesia; Animals; Biocompatible Materials; Capsules; Hypoglycemia; Ileum; Insulin; Lactic Acid; M | 1999 |
Brain substrate utilisation during acute hypoglycaemia.
Topics: Acute Disease; Adult; Amino Acids; Blood Glucose; Brain; Glucose Clamp Technique; Humans; Hypoglycem | 1999 |
Effects of fasting and insulin-induced hypoglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blood Glucose; Brain; Brain Chemistry; Cell Membr | 1999 |
Pharmacokinetics and pharmacodynamics of dichloroacetate in patients with cirrhosis.
Topics: Adult; Blood Glucose; Case-Control Studies; Dichloroacetic Acid; Female; Humans; Hypoglycemia; Lacti | 1999 |
Liver transplantation in mitochondrial respiratory chain disorders.
Topics: Electron Transport; Female; Humans; Hypoglycemia; Infant; Infant, Newborn; Lactic Acid; Liver Failur | 1999 |
Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.
Topics: Age Factors; Blood Glucose; Cross-Sectional Studies; Energy Metabolism; Fatty Acids, Nonesterified; | 2000 |
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid | 2000 |
Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle.
Topics: Ammonia; Cardiac Output, Low; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Coma; Consangu | 2000 |
Hyperlipidemia with hypoglycemia reduces myocardial oxygen utilization efficiency but not contractile function during coronary hypoperfusion.
Topics: Animals; Blood Glucose; Dogs; Fatty Acids; Female; Glucose; Glycogen; Hemodynamics; Hyperlipidemias; | 2000 |
Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Cold Temperature; Consciousness; Dogs; Epine | 2000 |
Monitoring of early postnatal glucose homeostasis and cerebral function in newborn infants of diabetic mothers. A pilot study.
Topics: Adult; Blood Glucose; Electroencephalography; Female; Glucose; Glycerol; Homeostasis; Humans; Hypogl | 2001 |
Alpha- and beta-cell responses to small changes in plasma glucose in the conscious dog.
Topics: Alanine; Animals; Arteries; Blood Glucose; Dogs; Female; Gluconeogenesis; Glucose; Glycerol; Glycoge | 2001 |
Energy fuel utilization by fetal versus young rabbit brain: a 13C MRS isotopomer analysis of [U-(13)C]glucose metabolites.
Topics: 3-Hydroxybutyric Acid; Age Factors; Amino Acids; Animals; Astrocytes; Brain; Carbon Isotopes; Energy | 2001 |
Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Adult; Alanine; Blood Glucose; Blood Pressure; E | 2001 |
Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet.
Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Gas Analysis; Blood | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycero | 2001 |
Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients.
Topics: Adult; Cardiac Output; Catecholamines; Chemical Precipitation; Diabetes Mellitus, Type 1; Diastole; | 2001 |
Effect of near physiologic insulin therapy on hypoglycemia counterregulation in type-1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, None | 2001 |
Severe hypoglycaemia in a patient with glycogen storage disease type III induced by infectious mononucleosis.
Topics: Female; Glycogen Storage Disease Type III; Humans; Hypoglycemia; Infant; Infectious Mononucleosis; L | 2001 |
Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus.
Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Adrenocorticotropic Hormone; Animals; Blood Gas Anal | 2002 |
Prior exercise and the response to insulin-induced hypoglycemia in the dog.
Topics: Animals; Blood Glucose; Carbon Radioisotopes; Catecholamines; Dogs; Energy Metabolism; Fatty Acids, | 2002 |
Prevention of overt hypoglycemia during exercise: stimulation of endogenous glucose production independent of hepatic catecholamine action and changes in pancreatic hormone concentration.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alanine; Animals; Blood Glucose; Dogs; Ep | 2002 |
Optimal daytime feeding regimen to prevent postprandial hypoglycemia in type 1 glycogen storage disease.
Topics: Adolescent; Adult; Blood Glucose; Child; Cholesterol; Eating; Female; Glycogen Storage Disease Type | 1992 |
Insulin-induced hypoglycemia in fed and fasted exercising rats.
Topics: Animals; Blood Glucose; Fasting; Fatigue; Fatty Acids, Nonesterified; Glycogen; Hypoglycemia; Infusi | 1992 |
Effect of hypoxia on cerebral metabolites measured by proton nuclear magnetic resonance spectroscopy in rats.
Topics: Animals; Aspartic Acid; Brain; Hyperglycemia; Hypoglycemia; Hypoxia; Lactates; Lactic Acid; Magnetic | 1991 |
Insulin, glucagon, and catecholamines in prevention of hypoglycemia during fasting.
Topics: Adult; Blood Glucose; C-Peptide; Catecholamines; Fasting; Fatty Acids, Nonesterified; Female; Glucag | 1989 |
Neonatal hyperlactacidemia and hypoglycemia caused by delayed maturation of fructose-1,6-diphosphatase activity.
Topics: Follow-Up Studies; Fructose-Bisphosphatase; Humans; Hypoglycemia; Infant, Newborn; Lactates; Lactic | 1988 |
Effect of hypoglycemic encephalopathy upon amino acids, high-energy phosphates, and pHi in the rat brain in vivo: detection by sequential 1H and 31P NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Electroencephalography; Glutamates; Glutamic Acid; Gluta | 1985 |
Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans.
Topics: Adult; Alanine; Blood Glucose; C-Peptide; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; | 1986 |
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo | 1989 |
Mechanism of exercise-induced hypoglycemia during sulfonylurea treatment.
Topics: Adult; C-Peptide; Glucagon; Glyburide; Humans; Hypoglycemia; Insulin; Kinetics; Lactates; Lactic Aci | 1987 |
Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs.
Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Female; Fetal Growth Retardation; Glycogen | 1988 |
Brain levels of NADH and NAD+ under hypoxic and hypoglycaemic conditions in vitro.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Glucose; Guinea Pigs; Hypoglycemia; Hypoxia, Brain; | 1988 |
In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure.
Topics: Animals; Animals, Newborn; Bicuculline; Brain; Cerebrovascular Circulation; Dogs; Glucose; Hemodynam | 1987 |
Rapid ethanol elimination in patients with type I glycogen storage disease is an adaptive change resulting from recurrent hypoglycemia.
Topics: Adaptation, Physiological; Adolescent; Adult; Blood Glucose; Child; Child, Preschool; Ethanol; Femal | 1986 |
Glucoregulation during exercise: hypoglycemia is prevented by redundant glucoregulatory systems, sympathochromaffin activation, and changes in islet hormone secretion.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Chromaffin System; Epinephrine; Fat | 1986 |
Regional cerebral glucose utilization during insulin-induced hypoglycemia in unanesthetized rats.
Topics: Animals; Blood Glucose; Brain; Glucose; Hypoglycemia; Insulin; Lactates; Lactic Acid; Male; Mathemat | 1986 |
Hypoglycemia following insulin and proinsulin. A comparison.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Humans; Hydrox | 1986 |
[Effect of postprandial exercise in type I diabetes: comparison between the continuous-infusion insulin pump and intensified conventional therapy].
Topics: Adult; Albuminuria; Blood Glucose; Diabetes Mellitus, Type 1; Eating; Exercise Test; Fatty Acids; Fe | 1986 |
Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Epinephrine; Fatty Acids, Nonesterified; Fem | 1987 |
[Effects of splanchnicotomy on plasma catecholamines, glucose and lactic acid during insulin hypoglycemia in sheep].
Topics: Animals; Blood Glucose; Catecholamines; Female; Hypoglycemia; Insulin; Lactates; Lactic Acid; Male; | 1986 |
Metabolic emergencies in cancer medicine.
Topics: Acidosis; ACTH Syndrome, Ectopic; Adrenal Insufficiency; Diagnosis, Differential; Emergencies; Human | 1986 |
Changes in extra- and intracellular pH in the brain during and following ischemia in hyperglycemic and in moderately hypoglycemic rats.
Topics: Acidosis; Animals; Brain; Extracellular Space; Hydrogen-Ion Concentration; Hyperglycemia; Hypoglycem | 1986 |
[Overdose of biguanides].
Topics: Acidosis; Adolescent; Biguanides; Buformin; Female; Humans; Hypoglycemia; Lactates; Lactic Acid | 1985 |