Page last updated: 2024-10-17

lactic acid and Hyperventilation

lactic acid has been researched along with Hyperventilation in 74 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.

Research Excerpts

ExcerptRelevanceReference
"It has been suggested that hyperventilation and the disproportionate increase in VCO2 versus VO2 above the ventilatory threshold (V(TH)) in ramp exercise are due to the production of nonmetabolic CO2 in muscle because of lactic acid buffering by plasma bicarbonate entering the cell in exchange with lactate [Wasserman, K."8.83Lactic acid buffering, nonmetabolic CO2 and exercise hyperventilation: a critical reappraisal. ( Aguilaniu, B; Péronnet, F, 2006)
"25 U), phosphocreatine (PCr) decreases (>30%), and adenosine triphosphate (ATP) decreases (>10%) after hyperventilation (HV) (20 mm Hg PaCO(2))."7.74Brain changes to hypocapnia using rapidly interleaved phosphorus-proton magnetic resonance spectroscopy at 4 T. ( Artru, AA; Dager, SR; Frederick, BB; Friedman, SD; Jensen, JE; Renshaw, PF, 2007)
" Measurement of pH in cerebrospinal fluid (CSF) yielded central lactic acidosis despite alkalosis in peripheral blood."7.74Central lactic acidosis, hyperventilation, and respiratory alkalosis: leading clinical features in a 3-year-old boy with malignant meningeal melanoma. ( Bierbach, U; Blüher, S; Hirsch, W; Kiess, W; Meixensberger, J; Schober, R; Schulz, M; Siekmeyer, W; Tröbs, RB, 2008)
" It is concluded that the greater EIH with treadmill running is a consequence of the combined effect of a reduced lactic acidosis-induced hyperventilation and greater ventilation-perfusion inequality with this exercise mode."5.09Arterial hypoxaemia in endurance athletes is greater during running than cycling. ( Chapman, MJ; Gore, CJ; Greville, HW; McNaughton, NS; Rice, AJ; Rogers, KJ; Scicchitano, R; Scroop, GC; Thornton, AT, 2000)
"10 at each work load); 2) hyperventilation following acetazolamide (which returned pH to control values despite ventilation and PaCO2 identical to condition 1); and 3) metabolic acidosis induced by acetazolamide (with spontaneous ventilation)."5.06Effect of respiratory alkalosis during exercise on blood lactate. ( Davies, SF; Iber, C; Keene, SA; McArthur, CD; Path, MJ, 1986)
"It has been suggested that hyperventilation and the disproportionate increase in VCO2 versus VO2 above the ventilatory threshold (V(TH)) in ramp exercise are due to the production of nonmetabolic CO2 in muscle because of lactic acid buffering by plasma bicarbonate entering the cell in exchange with lactate [Wasserman, K."4.83Lactic acid buffering, nonmetabolic CO2 and exercise hyperventilation: a critical reappraisal. ( Aguilaniu, B; Péronnet, F, 2006)
"25 U), phosphocreatine (PCr) decreases (>30%), and adenosine triphosphate (ATP) decreases (>10%) after hyperventilation (HV) (20 mm Hg PaCO(2))."3.74Brain changes to hypocapnia using rapidly interleaved phosphorus-proton magnetic resonance spectroscopy at 4 T. ( Artru, AA; Dager, SR; Frederick, BB; Friedman, SD; Jensen, JE; Renshaw, PF, 2007)
" Measurement of pH in cerebrospinal fluid (CSF) yielded central lactic acidosis despite alkalosis in peripheral blood."3.74Central lactic acidosis, hyperventilation, and respiratory alkalosis: leading clinical features in a 3-year-old boy with malignant meningeal melanoma. ( Bierbach, U; Blüher, S; Hirsch, W; Kiess, W; Meixensberger, J; Schober, R; Schulz, M; Siekmeyer, W; Tröbs, RB, 2008)
" Extracellular pH defense against lactic acidosis was estimated from changes (Delta) in lactic acid ([La]), [HCO3-], pH and PCO2 in plasma, which equilibrates with interstitial fluid."3.74Extracellular pH defense against lactic acid in untrained and trained altitude residents. ( Böning, D; Coy, L; Mora, M; Reyes, O; Rojas, J; Serrato, M, 2008)
"The purpose of this study was to compare the effect of hyperventilation and indomethacin on cerebral circulation, metabolism and pressures in patients with acute severe head injury in order to see if indomethacin may act supplementary to hyperventilation."3.69CO(2) and indomethacin vasoreactivity in patients with head injury. ( Astrup, J; Bergholt, B; Cold, GE; Dahl, B; Jensen, K; Kjaersgaard, JO; Mosdal, B, 1996)
"Hyperventilation-induced respiratory alkalosis can enhance WAnT cycling sprint performance well in the magnitude of what is seen after successful bicarbonate ingestion."2.82Enhancement on Wingate Anaerobic Test Performance With Hyperventilation. ( Beneke, R; Böning, D; Hütler, M; Leithäuser, RM, 2016)
"Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown."2.79Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux. ( Grüne, F; Kazmaier, S; Sonntag, H; Stolker, RJ; Weyland, A, 2014)
"To evaluate the impact of respiratory alkalosis on the elimination of intravenously infused lactate."2.67Lactic acid kinetics in respiratory alkalosis. ( Druml, W; Grimm, G; Laggner, AN; Lenz, K; Schneeweiss, B, 1991)
"Acute hyperventilation is neither necessary nor sufficient for panic to occur."2.38Carbon dioxide hypersensitivity, hyperventilation, and panic disorder. ( Gorman, JM; Klein, DF; Papp, LA, 1993)
"Cerebral blood flow after cardiac arrest is reduced during the delayed hypoperfusion phase, while cerebral metabolic rate of oxygen returns to baseline values."1.30Cerebrovascular reactivity in comatose patients resuscitated from a cardiac arrest. ( Buunk, G; Meinders, AE; van der Hoeven, JG, 1997)
"Alkalosis is prominent among the many physiologic and biochemical effects of sodium lactate infusion."1.27Blood gas changes and hypophosphatemia in lactate-induced panic. ( Cohen, BS; Davies, SO; Fyer, AJ; Gorman, JM; Klein, DF; Liebowitz, MR; Ross, D, 1986)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199024 (32.43)18.7374
1990's19 (25.68)18.2507
2000's22 (29.73)29.6817
2010's9 (12.16)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suarez, N1
Conway, N1
Pickett, T1
Sakamoto, A1
Naito, H1
Chow, CM1
Grüne, F1
Kazmaier, S1
Sonntag, H1
Stolker, RJ1
Weyland, A1
Rostami, E1
Rocksén, D1
Ekberg, NR1
Goiny, M1
Ungerstedt, U1
Péronnet, F2
Aguilaniu, B2
Leithäuser, RM1
Böning, D2
Hütler, M1
Beneke, R1
Brown, PI2
Sharpe, GR3
Johnson, MA3
Yano, T2
Yunoki, T2
Matsuura, R2
Arimitsu, T2
Renggli, AS2
Verges, S2
Notter, DA2
Spengler, CM2
Hopker, JG1
Jobson, SA1
Pandit, JJ1
Magnotta, VA1
Heo, HY1
Dlouhy, BJ1
Dahdaleh, NS1
Follmer, RL1
Thedens, DR1
Welsh, MJ1
Wemmie, JA1
Tofteng, F1
Jorgensen, L1
Hansen, BA1
Ott, P1
Kondrup, J1
Larsen, FS1
Marion, DW2
Puccio, A1
Wisniewski, SR1
Kochanek, P1
Dixon, CE1
Bullian, L1
Carlier, P1
Zornow, MH1
Prough, DS1
Hug, F1
Faucher, M1
Kipson, N1
Jammes, Y1
HUCKABEE, WE1
CAIN, SM1
NAIMARK, A1
JONES, NL1
LAL, S1
FRANKEL, HM1
SYKES, MK1
COOKE, PM1
Gargaglioni, LH1
Bicego, KC1
Steiner, AA1
Branco, LG2
Gaviani, P1
Gonzalez, RG1
Zhu, JJ1
Batchelor, TT1
Henson, JW1
McConnell, AK1
Ogata, H1
Horiuchi, M1
Soustiel, JF1
Mahamid, E1
Chistyakov, A1
Shik, V1
Benenson, R1
Zaaroor, M1
Friedman, SD1
Jensen, JE1
Frederick, BB1
Artru, AA2
Renshaw, PF1
Dager, SR2
Whipp, BJ2
Ward, SA2
Blüher, S1
Schulz, M1
Bierbach, U1
Meixensberger, J1
Tröbs, RB1
Hirsch, W1
Schober, R1
Kiess, W1
Siekmeyer, W1
Burtscher, M1
Szubski, C1
Faulhaber, M1
Rojas, J1
Serrato, M1
Reyes, O1
Coy, L1
Mora, M1
Scheen, A1
Lemaire, P1
Liu, CY1
Bettice, JA1
Owens, D1
Riley, S1
Gorman, JM6
Askanazi, J2
Liebowitz, MR5
Fyer, AJ5
Stein, J1
Kinney, JM1
Klein, DF5
Carr, DB1
Sheehan, DV1
Young, RS1
Yagel, SK1
Shephard, RJ1
Grote, J1
Zimmer, K1
Schubert, R1
Hagberg, JM1
Coyle, EF1
Carroll, JE1
Miller, JM1
Martin, WH1
Brooke, MH1
Pörtner, HO1
Wood, SC1
Papp, LA1
Siderowf, AD1
Balcer, LJ1
Kenyon, LC1
Nei, M1
Raps, EC1
Galetta, SL1
Dahl, B1
Bergholt, B1
Cold, GE1
Astrup, J1
Mosdal, B1
Jensen, K1
Kjaersgaard, JO1
Cheung, PY1
Posse, S1
Richards, TL1
Yuan, C1
Ogg, R1
Müller-Gärtner, HW1
Hayes, C1
Buunk, G1
van der Hoeven, JG1
Meinders, AE1
Schneider, DA1
Berwick, JP1
Schaffranietz, L1
Heinke, W1
Ozcelik, O1
Letarte, PB1
Puccio, AM1
Brown, SD1
Shiogai, T1
Nara, I1
Saruta, K1
Hara, M1
Saito, I1
Rice, AJ1
Scroop, GC1
Thornton, AT1
McNaughton, NS1
Rogers, KJ1
Chapman, MJ1
Greville, HW1
Scicchitano, R1
Gore, CJ1
Hutchinson, PJ1
Gupta, AK1
Fryer, TF1
Al-Rawi, PG1
Chatfield, DA1
Coles, JP1
O'Connell, MT1
Kett-White, R1
Minhas, PS1
Aigbirhio, FI1
Clark, JC1
Kirkpatrick, PJ1
Menon, DK1
Pickard, JD1
Powers, SK1
Martin, D1
Cicale, M1
Collop, N1
Huang, D1
Criswell, D1
Nutt, D1
Lawson, C1
Maddock, RJ2
Carter, CS1
Gietzen, DW1
Druml, W1
Grimm, G1
Laggner, AN1
Lenz, K1
Schneeweiss, B1
Krendel, DA1
Pilch, JF1
Stahl, RL1
Goetz, RR1
Dillon, D2
Davies, S1
Mateo-Bermudez, J1
Frewen, TC1
Sumabat, WO1
Han, VK1
Campbell, K1
Tiffin, N1
Fyer, MR1
Goetz, R1
Kinney, J1
Judd, FK1
Burrows, GD1
Norman, TR1
George, DT1
Nutt, DJ1
Walker, WV1
Porges, SW1
Adinoff, B1
Linnoila, M1
Rainey, JM1
Nesse, RM1
Pan, LG1
Forster, HV1
Bisgard, GE1
Murphy, CL1
Lowry, TF1
Cohen, BS1
Ross, D1
Davies, SO2
Davies, SF1
Iber, C1
Keene, SA1
McArthur, CD1
Path, MJ1
Levitt, M1
Levy, G1
Appleby, IL1
Anderson, S1
Palij, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cerebral Microdialysis in Patients With Fulminant Hepatic Failure[NCT00836420]50 participants (Actual)Observational2000-01-31Completed
The Effect of Breast Reconstruction Surgery Using Tissue Expanders on Respiratory Functions[NCT02491762]45 participants (Anticipated)Observational2015-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for lactic acid and Hyperventilation

ArticleYear
[Physiological significance and interpretation of plasma lactate concentration and pH in clinical exercise testing].
    Revue des maladies respiratoires, 2014, Volume: 31, Issue:6

    Topics: Aerobiosis; Anaerobic Threshold; Blood Chemical Analysis; Exercise; Exercise Test; Humans; Hydrogen-

2014
Controversies in the physiological basis of the 'anaerobic threshold' and their implications for clinical cardiopulmonary exercise testing.
    Anaesthesia, 2011, Volume: 66, Issue:2

    Topics: Anaerobic Threshold; Carotid Body; Exercise; Exercise Test; Humans; Hyperventilation; Lactic Acid; T

2011
Lactic acid buffering, nonmetabolic CO2 and exercise hyperventilation: a critical reappraisal.
    Respiratory physiology & neurobiology, 2006, Jan-25, Volume: 150, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Buffers; Carbon Dioxide; Exercise; Humans; Hyperventil

2006
Physiological mechanisms dissociating pulmonary CO2 and O2 exchange dynamics during exercise in humans.
    Experimental physiology, 2007, Volume: 92, Issue:2

    Topics: Anaerobic Threshold; Carbon Dioxide; Exercise; Exercise Tolerance; Humans; Hyperventilation; Kinetic

2007
Ventilatory control in humans: constraints and limitations.
    Experimental physiology, 2007, Volume: 92, Issue:2

    Topics: Carbon Dioxide; Exercise; Exercise Tolerance; Humans; Hyperventilation; Lactic Acid; Models, Biologi

2007
Panic anxiety: a new biological model.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Anxiety Disorders; Brain Stem; Carbon Dioxide; Fear; Humans; Hyperventilation; Lactates; Lactic Acid

1984
Exercise-induced bronchospasm - pathophysiology and treatment.
    Canadian journal of applied sport sciences. Journal canadien des sciences appliquees au sport, 1981, Volume: 6, Issue:3

    Topics: Adult; Age Factors; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Carbon Dioxide; Child;

1981
Carbon dioxide hypersensitivity, hyperventilation, and panic disorder.
    The American journal of psychiatry, 1993, Volume: 150, Issue:8

    Topics: Alkalosis, Respiratory; Carbon Dioxide; Cognitive Behavioral Therapy; Humans; Hyperventilation; Lact

1993
Panic attacks. A neurochemical overview of models and mechanisms.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Bicarbonates; Caffeine; Female; Humans; Hypercapnia; Hyperventilation; Lactates; Lactic Acid; Male;

1992
Psychobiology of anxiety and anxiety disorders.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Animals; Anxiety; Anxiety Disorders; Blood Platelets; Caffeine; Carbolines; Carbon Dioxide; Cats; Di

1985

Trials

9 trials available for lactic acid and Hyperventilation

ArticleYear
Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux.
    Anesthesiology, 2014, Volume: 120, Issue:2

    Topics: Adult; Aerobiosis; Aged; Anesthesia, Intravenous; Blood Gas Analysis; Brain Chemistry; Carbon Dioxid

2014
Enhancement on Wingate Anaerobic Test Performance With Hyperventilation.
    International journal of sports physiology and performance, 2016, Volume: 11, Issue:7

    Topics: Acid-Base Equilibrium; Adult; Alkalosis, Respiratory; Anaerobic Threshold; Bicarbonates; Biomarkers;

2016
Inspiratory muscle training reduces blood lactate concentration during volitional hyperpnoea.
    European journal of applied physiology, 2008, Volume: 104, Issue:1

    Topics: Adult; Breathing Exercises; Diaphragm; Humans; Hyperventilation; Inhalation; Intercostal Muscles; La

2008
Detecting activity-evoked pH changes in human brain.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-22, Volume: 109, Issue:21

    Topics: Acidosis; Adult; Animals; Bicarbonates; Brain; Brain Mapping; Buffers; Carbon Dioxide; Cerebrovascul

2012
Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury.
    Critical care medicine, 2002, Volume: 30, Issue:12

    Topics: Adult; Brain; Brain Injuries; Brain Ischemia; Female; Glutamic Acid; Humans; Hyperventilation; Lacti

2002
Comparison of moderate hyperventilation and mannitol for control of intracranial pressure control in patients with severe traumatic brain injury--a study of cerebral blood flow and metabolism.
    Acta neurochirurgica, 2006, Volume: 148, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Edema; Brain Injuries; Brain Ischemia; Cerebral Cortex; Cerebrovascul

2006
Arterial hypoxaemia in endurance athletes is greater during running than cycling.
    Respiration physiology, 2000, Volume: 123, Issue:3

    Topics: Acidosis, Lactic; Adult; Arteries; Blood Gas Analysis; Exercise Test; Humans; Hydrogen-Ion Concentra

2000
Lactic acid kinetics in respiratory alkalosis.
    Critical care medicine, 1991, Volume: 19, Issue:9

    Topics: Aged; Alkalosis, Respiratory; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Hyperventilatio

1991
Effect of respiratory alkalosis during exercise on blood lactate.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:3

    Topics: Acetazolamide; Acidosis; Adult; Alkalosis, Respiratory; Biofeedback, Psychology; Female; Humans; Hyd

1986

Other Studies

55 other studies available for lactic acid and Hyperventilation

ArticleYear
Panic-related hyperventilation resulting in hypophosphataemia and a high lactate.
    BMJ case reports, 2013, May-09, Volume: 2013

    Topics: Adult; Chest Pain; Dyspnea; Female; Humans; Hyperventilation; Hypophosphatemia; Lactic Acid; Panic;

2013
Hyperventilation as a strategy for improved repeated sprint performance.
    Journal of strength and conditioning research, 2014, Volume: 28, Issue:4

    Topics: Acid-Base Imbalance; Adaptation, Physiological; Bicycling; Blood Gas Analysis; Ergometry; Exercise T

2014
Brain metabolism and oxygenation in healthy pigs receiving hypoventilation and hyperoxia.
    Respiratory physiology & neurobiology, 2013, Dec-01, Volume: 189, Issue:3

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain; Heart Rate; Hyperventilation; Hypoventilation; I

2013
Relationship between hyperventilation and excessive CO2 output during recovery from repeated cycling sprints.
    Physiological research, 2009, Volume: 58, Issue:4

    Topics: Bicycling; Carbon Dioxide; Exercise Tolerance; Humans; Hyperventilation; Lactic Acid; Male; Oxygen C

2009
Development of respiratory muscle contractile fatigue in the course of hyperpnoea.
    Respiratory physiology & neurobiology, 2008, Dec-31, Volume: 164, Issue:3

    Topics: Analysis of Variance; Electric Stimulation; Electromyography; Humans; Hyperventilation; Lactic Acid;

2008
Effects of different respiratory muscle training regimes on fatigue-related variables during volitional hyperpnoea.
    Respiratory physiology & neurobiology, 2009, Dec-31, Volume: 169, Issue:3

    Topics: Adult; Analysis of Variance; Breathing Exercises; Humans; Hyperventilation; Lactic Acid; Lung; Male;

2009
Inspiratory muscle training abolishes the blood lactate increase associated with volitional hyperpnoea superimposed on exercise and accelerates lactate and oxygen uptake kinetics at the onset of exercise.
    European journal of applied physiology, 2012, Volume: 112, Issue:6

    Topics: Adult; Arteries; Breathing Exercises; Education; Exercise; Heart Rate; Humans; Hyperventilation; Kin

2012
Cerebral microdialysis in patients with fulminant hepatic failure.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:6

    Topics: Adult; Female; Glutamic Acid; Humans; Hyperventilation; Hypnotics and Sedatives; Hypothermia, Induce

2002
Does acute hyperventilation cause cerebral ischemia in severely head-injured patients?
    Critical care medicine, 2002, Volume: 30, Issue:12

    Topics: Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Respiration, A

2002
EMG signs of neuromuscular fatigue related to the ventilatory threshold during cycling exercise.
    Clinical physiology and functional imaging, 2003, Volume: 23, Issue:4

    Topics: Acidosis, Lactic; Adult; Electromyography; Exercise Test; Female; Humans; Hydrogen-Ion Concentration

2003
Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation.
    The Journal of clinical investigation, 1958, Volume: 37, Issue:2

    Topics: Glucose; Hyperventilation; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid

1958
Cerebral excess lactate production during hyperventilation of anesthetized dogs.
    Technical documentary report. SAM-TDR. USAF School of Aerospace Medicine, 1962, Volume: 62-109

    Topics: Animals; Cell Respiration; Dogs; Humans; Hyperventilation; Hypoxia, Brain; Lactates; Lactic Acid; Re

1962
THE EFFECT OF HYPOXIA ON GAS EXCHANGE AND ARTERIAL LACTATE AND PYRUVATE CONCENTRATION DURING MODERATE EXERCISE IN MAN.
    Clinical science, 1965, Volume: 28

    Topics: Arteries; Blood; Carbon Dioxide; Exercise; Humans; Hydrogen-Ion Concentration; Hyperventilation; Hyp

1965
BLOOD LACTATE AND PYRUVATE AND EVIDENCE FOR HYPOCAPNIC LACTICACIDOSIS IN THE CHICKEN.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Acidosis; Animals; Bicarbonates; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Chickens; Hyperv

1965
THE EFFECT OF HYPERVENTILATION OF "EXCESS LACTATE" PRODUCTION DURING ANAESTHESIA.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Acid-Base Equilibrium; Anesthesia; Anesthesia, Inhalation; Anesthesiology; Hyperventilation; Lactate

1965
Lactate as a modulator of hypoxia-induced hyperventilation.
    Respiratory physiology & neurobiology, 2003, Oct-16, Volume: 138, Issue:1

    Topics: Acidosis, Lactic; Animals; Dichloroacetic Acid; Enzyme Inhibitors; Hyperventilation; Hypoxia; Lactic

2003
Central neurogenic hyperventilation and lactate production in brainstem glioma.
    Neurology, 2005, Jan-11, Volume: 64, Issue:1

    Topics: Adult; Brain Stem Neoplasms; Female; Glioma; Humans; Hyperventilation; Lactic Acid

2005
Maximal voluntary hyperpnoea increases blood lactate concentration during exercise.
    European journal of applied physiology, 2006, Volume: 96, Issue:5

    Topics: Adult; Carbon Dioxide; Exercise; Exercise Test; Heart Rate; Humans; Hypercapnia; Hyperventilation; L

2006
Relationship between oxygenation in inactive biceps brachii muscle and hyperventilation during leg cycling.
    Physiological research, 2007, Volume: 56, Issue:1

    Topics: Adult; Anaerobic Threshold; Bicycling; Carbon Dioxide; Exercise; Exercise Test; Heart Rate; Hemoglob

2007
Brain changes to hypocapnia using rapidly interleaved phosphorus-proton magnetic resonance spectroscopy at 4 T.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:3

    Topics: Adenosine Triphosphate; Adult; Brain; Female; Humans; Hydrogen-Ion Concentration; Hyperventilation;

2007
Central lactic acidosis, hyperventilation, and respiratory alkalosis: leading clinical features in a 3-year-old boy with malignant meningeal melanoma.
    European journal of pediatrics, 2008, Volume: 167, Issue:4

    Topics: Acidosis, Lactic; Alkalosis, Respiratory; Child, Preschool; Diagnosis, Differential; Fatal Outcome;

2008
Prediction of the susceptibility to AMS in simulated altitude.
    Sleep & breathing = Schlaf & Atmung, 2008, Volume: 12, Issue:2

    Topics: Acclimatization; Acute Disease; Altitude; Altitude Sickness; Exercise; Humans; Hypercapnia; Hyperven

2008
Extracellular pH defense against lactic acid in untrained and trained altitude residents.
    European journal of applied physiology, 2008, Volume: 103, Issue:2

    Topics: Acclimatization; Acid-Base Equilibrium; Acidosis, Lactic; Adaptation, Physiological; Adult; Altitude

2008
[A reduction in the hyperventilation threshold by intravenous infusion of adrenaline in the treadmill exercise].
    Archives internationales de physiologie et de biochimie, 1983, Volume: 91, Issue:3

    Topics: Blood Pressure; Epinephrine; Heart Rate; Humans; Hyperventilation; Infusions, Parenteral; Lactates;

1983
[Tissue oxygen and carbon dioxide partial pressure changes in normal subjects during hyperventilation].
    Zhonghua nei ke za zhi, 1983, Volume: 22, Issue:4

    Topics: Adult; Carbon Dioxide; Female; Humans; Hyperventilation; Lactates; Lactic Acid; Male; Middle Aged; M

1983
The effects of hypocapnia on intracellular pH and bicarbonate.
    Respiration physiology, 1984, Volume: 55, Issue:1

    Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Animals; Bicarbonates; Body Fluids; Carbon Dioxide; H

1984
Response to hyperventilation in a group of patients with panic disorder.
    The American journal of psychiatry, 1984, Volume: 141, Issue:7

    Topics: Adult; Alkalosis, Respiratory; Anxiety Disorders; Blood-Brain Barrier; Carbon Dioxide; Fear; Female;

1984
Cerebral physiological and metabolic effects of hyperventilation in the neonatal dog.
    Annals of neurology, 1984, Volume: 16, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blood Glucose; Brain; Brain Ischemia; Carbon Diox

1984
Effects of severe arterial hypocapnia on regional blood flow regulation, tissue PO2 and metabolism in the brain cortex of cats.
    Pflugers Archiv : European journal of physiology, 1981, Volume: 391, Issue:3

    Topics: Adenine Nucleotides; Animals; Carbon Dioxide; Cats; Cerebral Cortex; Cerebrovascular Circulation; Gl

1981
Exercise hyperventilation in patients with McArdle's disease.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1982, Volume: 52, Issue:4

    Topics: Adult; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; Hyperventilation;

1982
Interaction between temperature and hypoxia in the alligator.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 2

    Topics: Alligators and Crocodiles; Animals; Body Temperature; Hydrogen-Ion Concentration; Hyperventilation;

1993
Central neurogenic hyperventilation in an awake patient with a pontine glioma.
    Neurology, 1996, Volume: 46, Issue:4

    Topics: Astrocytoma; Brain Neoplasms; Cerebrospinal Fluid; Humans; Hydrogen-Ion Concentration; Hyperventilat

1996
CO(2) and indomethacin vasoreactivity in patients with head injury.
    Acta neurochirurgica, 1996, Volume: 138, Issue:3

    Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Craniocerebral Trauma; Hum

1996
Hyperlactatemia associated with hypocarbic hyperventilation.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:1

    Topics: Animals; Hyperventilation; Lactic Acid; Swine

1996
In vivo measurement of regional brain metabolic response to hyperventilation using magnetic resonance: proton echo planar spectroscopic imaging (PEPSI).
    Magnetic resonance in medicine, 1997, Volume: 37, Issue:6

    Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Choline; Creatine; Echo-Planar Imaging;

1997
Cerebrovascular reactivity in comatose patients resuscitated from a cardiac arrest.
    Stroke, 1997, Volume: 28, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Cerebral Arteries; Cerebrovascular Circulation;

1997
VE and VCO2 remain tightly coupled during incremental cycling performed after a bout of high-intensity exercise.
    European journal of applied physiology and occupational physiology, 1998, Volume: 77, Issue:1-2

    Topics: Acidosis; Adult; Bicycling; Exercise; Female; Humans; Hyperventilation; Lactic Acid; Pulmonary Gas E

1998
The effect of different ventilation regimes on jugular venous oxygen saturation in elective neurosurgical patients.
    Neurological research, 1998, Volume: 20 Suppl 1

    Topics: Adult; Aged; Brain; Humans; Hyperventilation; Jugular Veins; Lactic Acid; Middle Aged; Oximetry; Oxy

1998
Effect of altered body CO2 stores on pulmonary gas exchange dynamics during incremental exercise in humans.
    Experimental physiology, 1999, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Bicycling; Carbon Dioxide; Differential Threshold; Exercise; Humans; Hyperventila

1999
Effect of hypocapnea on CBF and extracellular intermediates of secondary brain injury.
    Acta neurochirurgica. Supplement, 1999, Volume: 75

    Topics: Brain; Brain Injuries; Carbon Dioxide; Chromatography, High Pressure Liquid; Extracellular Space; Gl

1999
Continuous monitoring of cerebrospinal fluid acid-base balance and oxygen metabolism in patients with severe head injury: pathophysiology and treatments for cerebral acidosis and ischemia.
    Acta neurochirurgica. Supplement, 1999, Volume: 75

    Topics: Acidosis; Adolescent; Adult; Brain Injuries; Brain Ischemia; Carbon Dioxide; Fever; Glasgow Coma Sca

1999
Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Female; Gluc

2002
Exercise-induced hypoxemia in athletes: role of inadequate hyperventilation.
    European journal of applied physiology and occupational physiology, 1992, Volume: 65, Issue:1

    Topics: Adult; Bicycling; Carbon Dioxide; Humans; Hyperventilation; Hypoxia; Lactates; Lactic Acid; Male; Ox

1992
Elevated serum lactate associated with panic attacks induced by hyperventilation.
    Psychiatry research, 1991, Volume: 38, Issue:3

    Topics: Adult; Body Mass Index; Diet; Female; Glycolysis; Heart Rate; Humans; Hydrocortisone; Hyperventilati

1991
Central hyperventilation in primary CNS lymphoma: evidence implicating CSF lactic acid.
    Neurology, 1991, Volume: 41, Issue:7

    Topics: Central Nervous System Diseases; Female; Humans; Hyperventilation; Lactates; Lactic Acid; Lymphoma;

1991
Sodium D-lactate infusion of panic disorder patients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:3

    Topics: Adult; Agoraphobia; Bicarbonates; Blood Pressure; Calcium; Carbon Dioxide; Fear; Female; Heart Rate;

1990
Elevated serum lactate following hyperventilation during glucose infusion in panic disorder.
    Biological psychiatry, 1990, Feb-15, Volume: 27, Issue:4

    Topics: Adult; Alkalosis, Respiratory; Anxiety Disorders; Fear; Female; Glucose; Humans; Hyperglycemia; Hype

1990
Effects of hyperventilation, hypothermia, and altered blood viscosity on cerebral blood flow, cross-brain oxygen extraction, and cerebral metabolic rate for oxygen in cats.
    Critical care medicine, 1989, Volume: 17, Issue:9

    Topics: Animals; Blood Viscosity; Brain Injuries; Cats; Cerebrovascular Circulation; Hyperventilation; Hypot

1989
Ventilatory physiology of patients with panic disorder.
    Archives of general psychiatry, 1988, Volume: 45, Issue:1

    Topics: Adult; Alkalosis; Anxiety Disorders; Blood Pressure; Carbon Dioxide; Fear; Female; Humans; Hypercapn

1988
The biological basis of anxiety. An overview.
    Journal of affective disorders, 1985, Volume: 9, Issue:3

    Topics: Anxiety Disorders; Carbon Dioxide; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Humans; Hypervent

1985
Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. A possible mechanism of panic provocation?
    Archives of general psychiatry, 1989, Volume: 46, Issue:2

    Topics: Adult; Anxiety Disorders; Arrhythmia, Sinus; Fear; Female; Heart; Humans; Hyperventilation; Lactates

1989
Independence of exercise hyperpnea and acidosis during high-intensity exercise in ponies.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:3

    Topics: Acidosis; Animals; Arteries; Bicarbonates; Carbon Dioxide; Carotid Body; Denervation; Heart Rate; Ho

1986
Blood gas changes and hypophosphatemia in lactate-induced panic.
    Archives of general psychiatry, 1986, Volume: 43, Issue:11

    Topics: Adult; Alkalosis; Alkalosis, Respiratory; Anxiety Disorders; Carbon Dioxide; Fear; Female; Humans; H

1986
Blood gas changes and hypophosphatemia in lactate-induced panic.
    Archives of general psychiatry, 1988, Volume: 45, Issue:1

    Topics: Anxiety Disorders; Carbon Dioxide; Fear; Humans; Hyperventilation; Lactates; Lactic Acid; Oxygen; Pa

1988
Lactate provocation of panic attacks. II. Biochemical and physiological findings.
    Archives of general psychiatry, 1985, Volume: 42, Issue:7

    Topics: Adult; Agoraphobia; Anxiety Disorders; Arousal; Calcium; Epinephrine; Fear; Female; Heart Rate; Huma

1985