lactic acid has been researched along with Hyperlactatemia in 120 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hyperlactatemia: Increase in blood LACTATE concentration often associated with SEPTIC SHOCK; LUNG INJURY; SEPSIS; and DRUG TOXICITY. When hyperlactatemia is associated with low body pH (acidosis) it is LACTIC ACIDOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When compared to cocaine exposure alone, CE exposure in ED patients with acute drug overdose was significantly associated with higher occurrence of cardiac arrest, higher mean lactate concentrations, and lower occurrence of myocardial injury." | 8.31 | Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose. ( Manini, AF; Manoochehri, O; Richardson, LD; Shastry, S, 2023) |
| " The present study aims to evaluate the factors that may contribute to the decision whether to start RRT or not and the potential impact of the start of RRT on the outcome in patients with severe lactic acidosis (SLA) (lactate ≥5 mmol/L)." | 8.12 | Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy. ( Hoste, EAJ; Kruse, JM; Van Biesen, W; Van De Ginste, L; Vanommeslaeghe, F; Verbeke, F, 2022) |
| "The inadequate intraoperative infusion rate of sufentanil is an independent risk factor for lactic acidosis after heart valve surgery." | 8.12 | Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery. ( Ge, YP; Jiang, W; Luo, TG; Pan, YC; Shi, Q; Xiao, ZH; Zhan, YF; Zheng, BS, 2022) |
| "Treatment of pediatric septic shock with thiamine was followed by rapid improvement in physiologic and clinical outcomes after prolonged hyperlactatemia." | 7.91 | Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock. ( Berg, RA; Blowey, B; Fitzgerald, JC; Ganetzky, R; Keele, L; Murali, CN; Sutton, RM; Weiss, SL, 2019) |
| " The primary outcomes were: (1) hyperlactatemia, defined as a lactate concentration ≥ 2 mmol/L at any point during hospital admission and, (2) metformin associated lactic acidosis (MALA), defined as a lactate concentration ≥ 5 mmol/L and pH <7." | 7.91 | Incidence and risk factors for hyperlactatemia in ED patients with acute metformin overdose. ( Hoffman, RS; Manini, AF; Taub, ES, 2019) |
| " No patient was hospitalized for lactic acidosis as the main diagnosis." | 7.85 | Metformin Does Not Induce Hyperlactatemia in Patients Admitted to Internal Medicine Ward. ( Doenyas-Barak, K; Golik, A; Koren, R; Koren, S; Zilberman-Itskovich, S, 2017) |
| " However, its use is limited because of potential lactic acidosis-associated adverse effects, particularly in renal impairment patients." | 7.85 | Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes. ( Cha, BS; Han, E; Hwang, S; Kang, ES; Kang, HP; Lee, BW; Lee, EY; Lee, HC; Lee, SH; Lee, W; Lee, YH; Lee, YM, 2017) |
| "Hyperlactatemia occurs during or after extracorporeal circulation in the form of lactic acidosis, increasing the risk of postoperative complications and the mortality rate." | 5.34 | Continuous ultrafiltration during extracorporeal circulation and its effect on lactatemia: A randomized controlled trial. ( Abellán-Hervás, MJ; García-Camacho, C; Lagares-Franco, C; Marín-Paz, AJ; Sáinz-Otero, AM, 2020) |
| " We carried out an electronic search in Medline and Scopus, using the keywords "COVID-19" OR "SARS-CoV-2" AND "lactate" OR "lactic acid" OR "hyperlactatemia", between 2019 and present time (i." | 5.22 | Blood lactate concentration in COVID-19: a systematic literature review. ( Carpenè, G; Fortunato, G; Henry, BM; Lippi, G; Nocini, R; Onorato, D; Rizk, JG, 2022) |
| "When compared to cocaine exposure alone, CE exposure in ED patients with acute drug overdose was significantly associated with higher occurrence of cardiac arrest, higher mean lactate concentrations, and lower occurrence of myocardial injury." | 4.31 | Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose. ( Manini, AF; Manoochehri, O; Richardson, LD; Shastry, S, 2023) |
| " The present study aims to evaluate the factors that may contribute to the decision whether to start RRT or not and the potential impact of the start of RRT on the outcome in patients with severe lactic acidosis (SLA) (lactate ≥5 mmol/L)." | 4.12 | Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy. ( Hoste, EAJ; Kruse, JM; Van Biesen, W; Van De Ginste, L; Vanommeslaeghe, F; Verbeke, F, 2022) |
| "The inadequate intraoperative infusion rate of sufentanil is an independent risk factor for lactic acidosis after heart valve surgery." | 4.12 | Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery. ( Ge, YP; Jiang, W; Luo, TG; Pan, YC; Shi, Q; Xiao, ZH; Zhan, YF; Zheng, BS, 2022) |
| "Treatment of pediatric septic shock with thiamine was followed by rapid improvement in physiologic and clinical outcomes after prolonged hyperlactatemia." | 3.91 | Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock. ( Berg, RA; Blowey, B; Fitzgerald, JC; Ganetzky, R; Keele, L; Murali, CN; Sutton, RM; Weiss, SL, 2019) |
| " The primary outcomes were: (1) hyperlactatemia, defined as a lactate concentration ≥ 2 mmol/L at any point during hospital admission and, (2) metformin associated lactic acidosis (MALA), defined as a lactate concentration ≥ 5 mmol/L and pH <7." | 3.91 | Incidence and risk factors for hyperlactatemia in ED patients with acute metformin overdose. ( Hoffman, RS; Manini, AF; Taub, ES, 2019) |
| "In patients presenting with acute type-A aortic dissection (aTAAD), lactic acid measurement is a frequently used analysis for diagnosis of acute ischemia, which may have a dismal prognosis." | 3.88 | Perioperative Hyperlactemia Is a Poor Predictor of Outcome in Patients Undergoing Surgery for Acute Type-A Aortic Dissection. ( Bjursten, H; Herou, E; Larsson, M; Luts, C; Nozohoor, S; Sjögren, J; Zindovic, I, 2018) |
| " Lactic acidosis was present in 42% and 80% of hyperlactatemic dogs and cats, respectively." | 3.88 | Retrospective evaluation of the prognostic utility of plasma lactate concentration, base deficit, pH, and anion gap in canine and feline emergency patients. ( Epstein, SE; Hopper, K; Kass, PH; Kohen, CJ, 2018) |
| " No patient was hospitalized for lactic acidosis as the main diagnosis." | 3.85 | Metformin Does Not Induce Hyperlactatemia in Patients Admitted to Internal Medicine Ward. ( Doenyas-Barak, K; Golik, A; Koren, R; Koren, S; Zilberman-Itskovich, S, 2017) |
| " However, its use is limited because of potential lactic acidosis-associated adverse effects, particularly in renal impairment patients." | 3.85 | Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes. ( Cha, BS; Han, E; Hwang, S; Kang, ES; Kang, HP; Lee, BW; Lee, EY; Lee, HC; Lee, SH; Lee, W; Lee, YH; Lee, YM, 2017) |
| " Peripheral venoarterial extracorporeal membrane oxygenation (splanchnic ECMO) may be more effective at reducing lactic acidosis for these patients." | 3.85 | Peripheral venoarterial extracorporeal membrane oxygenation for severe hyperlactataemia after cardiac surgery: a pilot study. ( Bellomo, R; Biesenbach, P; Crisman, M; Ghanpur, R; Hilton, A; Lindstrom, S; Mårtensson, J; Matalanis, G, 2017) |
| "Eligible septic shock patients who consented to participation in the study were randomly assigned to receive early lactate-guided treatment or regular treatment as controls." | 3.11 | Early Lactate-Guided Resuscitation of Elderly Septic Patients. ( Chen, H; Tong, F; Wang, X; Wang, Y; Xu, J, 2022) |
| "Hyperlactatemia was not associated with length of time to DKA resolution and length of hospital stay." | 3.01 | Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit. ( Li, Y; Liu, J; Yan, H, 2021) |
| "The etiology of hyperlactatemia is complex and multifactorial." | 2.58 | Clinical use of plasma lactate concentration. Part 1: Physiology, pathophysiology, and measurement. ( Hughes, D; Rosenstein, PG; Tennent-Brown, BS, 2018) |
| "Hyperlactatemia is common in critically ill patients and has a variety of etiologies." | 2.55 | Drug-induced hyperlactatemia. ( Blohm, E; Lai, J; Neavyn, M, 2017) |
| "Early-onset hyperlactatemia is that which develops in the operating room or very early following intensive care unit (ICU) admission." | 2.55 | Hyperlactatemia and Cardiac Surgery. ( Minton, J; Sidebotham, DA, 2017) |
| "Hence, hyperlactatemia is closely associated with disease severity but it is an epiphenomenon as the body attempts to protect itself." | 2.55 | Update: Clinical Use of Plasma Lactate. ( Gillespie, Í; Hughes, D; Rosenstein, PG, 2017) |
| "Hyperlactatemia was associated with in-hospital mortality (Odds Ratio [OR] 1." | 1.91 | Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis. ( Doola, R; Kumar, A; Laupland, KB; Ramanan, M; Shaikh, A; Tabah, A; Zahumensky, A, 2023) |
| "VTE risk and blood hyperlactatemia have been associated with a higher mortality risk in critically ill Covid-19 patients who are hospitalized in the ICU in Saudi Arabia." | 1.91 | The risk of venous thromboembolism and blood hyperlactatemia is associated with increased mortality among critically ill patients with Covid-19. ( Ali Khan, I; AlQarni, HM; Alshammary, AF; Farzan, R; Vennu, V, 2023) |
| "Hyperlactatemia is associated with mortality outcomes in patients undergoing CRRT for acute kidney injury." | 1.91 | Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury. ( Han, SS; Joo, KW; Kang, MW; Kim, DK; Kim, SG; Kim, YC; Kim, YS; Lee, J; Oh, KH; Yun, D, 2023) |
| "Baseline respiration at the time of septic shock diagnosis was correlated with lactate (Spearman -0." | 1.72 | Association Between Hyperlactatemia, Perfusional Parameters, and Lymphocyte Mitochondrial Dysfunction in Septic Shock Patients. ( Friedman, G; Júnior, JA; Kopczynski, A; Montes, THM; Nedel, WL; Portela, LV; Rodolphi, MS; Strogulski, NR, 2022) |
| "We reviewed episodes of diabetic ketoacidosis from 79 diabetes patients (one episode per patient)." | 1.72 | Hyperlactatemia in diabetic ketoacidosis. ( Brooks, GA; Lazar, AA; Masharani, U; Strycker, LA; Wu, K, 2022) |
| "Surgical repair for postinfarction ventricular septal rupture (VSR) is a challenging operation, especially in the acute phase with unstable hemodynamics." | 1.72 | Hyperlactatemia as a Risk Stratification for Postinfarction Ventricular Septal Rupture. ( Asai, T; Kinoshita, T; Suzuki, T, 2022) |
| "Hyperlactatemia is a common finding in critically ill patients and has significant prognostic implications." | 1.72 | Could lactate clearance be a marker of mortality in pediatric intensive care unit? ( Ağın, H; Atakul, G; Ceylan, G; Çolak, M; Karaarslan, ÜU; Sandal, ÖS; Sarı, F; Soydan, E; Topal, S, 2022) |
| "Sepsis and septic shock represent a significant worldwide mortality burden." | 1.72 | Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study. ( Cave, G; Chalmers, D; Greenberg, M; O'Beirn, S; Schneider, L, 2022) |
| "Severe hyperlactatemia was associated with death in the ICU (p < 0." | 1.72 | Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors. ( Claus, S; Fichtner-Feigl, S; Kousoulas, L; Lederer, AK; Runkel, M; Spiegelberg, J; Utzolino, S, 2022) |
| " The aim of this study was to determine a supposed correlation between the variables lactate peak concentration and clearance in the blood and mortality in the ECLS context." | 1.72 | Elevated lactate levels and impaired lactate clearance during extracorporeal life support (ECLS) are associated with poor outcome in cardiac surgery patients. ( Albers, J; Bodenstein, M; Dohle, DS; Koelm, S; Kriege, M; Oezkur, M; Rissel, R; Schepers, M, 2022) |
| "Hyperlactatemia is a common complication in critically ill patients with high morbidity and mortality." | 1.72 | Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study. ( Bai, M; Li, L; Sun, S; Zhang, Q, 2022) |
| "Sepsis is a potentially lethal syndrome resulting from a maladaptive response to infection." | 1.62 | Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis. ( Carmeliet, P; De Bosscher, K; Dewaele, S; Dewerchin, M; Dewyse, L; Eggermont, M; Libert, C; Moita, LF; Nuyttens, L; Paakinaho, V; Palvimo, JJ; Sponholz, C; Timmermans, S; Van de Voorde, J; van Grunsven, LA; Van Looveren, K; Van Wyngene, L; Vancraeynest, L; Vanderhaeghen, T; Vandewalle, J; Velho, TR; Wallaeys, C; Weis, S, 2021) |
| "Hyperlactatemia was defined as a lactate level of over 2 mmol/L." | 1.62 | Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short- and long-term mortality risk. ( Ak, R; Cimilli Ozturk, T; Kırkpantur, ED; Sakal, C; Taşçı, A; Ünal Akoğlu, E, 2021) |
| "Severe hyperlactatemia was also more common in CDI patients; during the cardiac procedure, 4 h and 12 h after surgery (p = 0." | 1.62 | Prognostic role of perioperative acid-base disturbances on the risk of Clostridioides difficile infection in patients undergoing cardiac surgery. ( Drwiła, R; Hymczak, H; Kapelak, B; Kędziora, A; Plicner, D; Rzucidło-Hymczak, A, 2021) |
| "BACKGROUND Hyperlactatemia is a common phenomenon following cardiac surgeries and is associated with prolonged ICU stay and higher morbidity and mortality rates, but such analyses have never focused on patients undergoing heart transplantation (HTX), in whom hyperlactatemia defined with the traditional threshold is observed in nearly every individual." | 1.56 | Postoperative Serum Lactate Levels for In-Hospital Mortality Prediction Among Heart Transplant Recipients. ( Drwiła, R; Górkiewicz-Kot, I; Hymczak, H; Kapelak, B; Kędziora, A; Milaniak, I; Piątek, J; Sobczyk, D; Tomsia, P; Wierzbicki, K, 2020) |
| "According to the new definition of septic shock, vasopressor therapy and hyperlactatemia are essential for diagnosis." | 1.51 | Risk factors for mortality in patients with low lactate level and septic shock. ( Choi, JY; Jeong, SJ; Jeong, WY; Jung, IY; Kim, EJ; Kim, JM; Kim, MH; Kim, YC; Ku, NS; Oh, DH; Song, JE; Song, YG, 2019) |
| "Among them, 23." | 1.51 | Blood lactate measurement within the emergency department: A two-year retrospective analysis. ( Contenti, J; Ferrari, P; Lemoel, F; Levraut, J; Occelli, C, 2019) |
| "Although hyperlactatemia is often developed in critically ill patients, it is unclear whether hyperlactatemia is associated with poor prognosis for surgical ICU (SICU) patients." | 1.48 | The incidence and outcome of hyperlactatemia in patients admitted to the intensive care unit after elective surgery. ( Abe, T; Sasabuchi, Y; Takinami, M; Uchino, S, 2018) |
| "Considering SGA being a proxy for fetal growth restriction, and acidemia a proxy for hypoxia, it is concluded that growth-restricted fetuses have an intact ability to develop lacticemia during hypoxia." | 1.48 | The small-for-gestational-age fetus has an intact ability to develop lacticemia when exposed to hypoxia: a retrospective comparative register study. ( Åkerman, F; Källén, K; Mokarami, P; Olofsson, P, 2018) |
| "Hyperlactatemia was defined as a blood lactate concentration ≥5mmol/L and high-grade hyperlactatemia a lactate level ≥10mmol/L." | 1.46 | Hyperlactatemia in ICU patients: Incidence, causes and associated mortality. ( Ayestarán, I; Ferreruela, M; Llompart-Pou, JA; Raurich, JM, 2017) |
| "Persistent hyperlactatemia is associated with adverse outcome in critically ill patients." | 1.46 | Hyperlactatemia and the Importance of Repeated Lactate Measurements in Critically Ill Patients. ( Godinjak, A; Iglica, A; Jusufovic, S; Kukuljac, A; Rama, A; Rozajac, S; Tancica, I; Zvizdic, F, 2017) |
| "Surgical repair of aortic dissection with preoperative laboratory samples drawn before patient transfer to the operating room or immediately after arterial catheter placement intraoperatively." | 1.46 | Hyperlactemia Predicts Surgical Mortality in Patients Presenting With Acute Stanford Type-A Aortic Dissection. ( Bennett, JM; Brophy, CM; Eagle, SS; Hocking, KM; Wise, ES, 2017) |
| "Hyperlactatemia was considered the concentration of lactate above 3 mmol/L." | 1.43 | [CLINICAL ASPECTS OF THE BLOOD LACTATE DYNAMICS DURING OPERATIONS ON THE HEART AND THE AORTA IN CONDITIONS OF CARDIOPULMONARY BYPASS.] ( Akselrod, BA; Gus'kov, DA; Markin, AV; Popov, AM; Trekova, NA; Yudichev, II, 2016) |
| "Hyperlactatemia was associated with death in the ICU [odds ratio 1." | 1.43 | Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients. ( Fuhrmann, V; Haas, SA; Kluge, S; Lange, T; Metschke, M; Petzoldt, M; Saugel, B, 2016) |
| "Persistent hyperlactatemia during septic shock is multifactorial." | 1.43 | Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock. ( Achurra, P; Alegría, L; Bakker, J; Bruhn, A; Castro, R; Gomez, J; Hernández, G; Jarufe, N; Kattan, E; Luengo, C; Ospina-Tascón, G; Rebolledo, R; Soto, D; Tapia, P, 2016) |
| "Alcoholic ketoacidosis (AKA) is a complex syndrome that results from disrupted metabolism in the setting of excessive alcohol use and poor oral intake." | 1.43 | A Patient With Alcoholic Ketoacidosis and Profound Lactemia. ( Gerrity, RS; Katz, KD; King, AM; Menke, NB; Pizon, AF, 2016) |
| "Metformin is a biguanaide antidiabetic drug used worldwide, and its effectiveness and benefits have already been established." | 1.43 | Investigation of Risk Factors Affecting Lactate Levels in Japanese Patients Treated with Metformin. ( Hiraoka, S; Nishihara, M; Tsuji, H; Yokoyama, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.83) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 70 (58.33) | 24.3611 |
| 2020's | 49 (40.83) | 2.80 |
| Authors | Studies |
|---|---|
| Van De Ginste, L | 1 |
| Vanommeslaeghe, F | 1 |
| Hoste, EAJ | 1 |
| Kruse, JM | 1 |
| Van Biesen, W | 1 |
| Verbeke, F | 1 |
| Weinberger, J | 1 |
| Klompas, M | 1 |
| Rhee, C | 1 |
| Sauer, CM | 1 |
| Gómez, J | 2 |
| Botella, MR | 1 |
| Ziehr, DR | 1 |
| Oldham, WM | 1 |
| Gavidia, G | 1 |
| Rodríguez, A | 1 |
| Elbers, P | 1 |
| Girbes, A | 1 |
| Bodi, M | 1 |
| Celi, LA | 1 |
| Nedel, WL | 1 |
| Strogulski, NR | 1 |
| Kopczynski, A | 1 |
| Rodolphi, MS | 1 |
| Montes, THM | 1 |
| Júnior, JA | 1 |
| Friedman, G | 1 |
| Portela, LV | 1 |
| Masharani, U | 1 |
| Strycker, LA | 1 |
| Lazar, AA | 1 |
| Wu, K | 1 |
| Brooks, GA | 1 |
| Carpenè, G | 1 |
| Onorato, D | 1 |
| Nocini, R | 1 |
| Fortunato, G | 1 |
| Rizk, JG | 1 |
| Henry, BM | 1 |
| Lippi, G | 1 |
| Lundström, P | 1 |
| Lauruschkus, K | 1 |
| Andersson, Å | 1 |
| Tornberg, ÅB | 1 |
| Huang, M | 1 |
| Tian, W | 1 |
| Luo, S | 1 |
| Xu, X | 1 |
| Yao, Z | 1 |
| Zhao, R | 1 |
| Huang, Q | 1 |
| Kinoshita, T | 1 |
| Asai, T | 1 |
| Suzuki, T | 1 |
| Vassilieva, A | 1 |
| Møller, K | 1 |
| Skjøth-Rasmussen, J | 1 |
| Sørensen, MK | 1 |
| Spiegelberg, J | 1 |
| Lederer, AK | 1 |
| Claus, S | 1 |
| Runkel, M | 1 |
| Utzolino, S | 1 |
| Fichtner-Feigl, S | 1 |
| Kousoulas, L | 1 |
| Khalil, MA | 1 |
| El Tahan, MR | 1 |
| Khidr, AM | 1 |
| Fallatah, S | 1 |
| Abohamar, AD | 1 |
| Amer, MM | 1 |
| Makhdom, F | 1 |
| El Ghoneimy, Y | 1 |
| Al Bassam, B | 1 |
| Alghamdi, T | 1 |
| Abdulfattah, D | 1 |
| Shastry, S | 1 |
| Manoochehri, O | 1 |
| Richardson, LD | 1 |
| Manini, AF | 2 |
| Aubourg, C | 1 |
| Collard, A | 1 |
| Léger, M | 1 |
| Gros, A | 1 |
| Fouquet, O | 1 |
| Sargentini, C | 1 |
| Rineau, E | 1 |
| Zhan, YF | 1 |
| Shi, Q | 1 |
| Pan, YC | 1 |
| Zheng, BS | 1 |
| Ge, YP | 1 |
| Luo, TG | 1 |
| Xiao, ZH | 1 |
| Jiang, W | 1 |
| Li, L | 1 |
| Bai, M | 1 |
| Zhang, Q | 1 |
| Sun, S | 1 |
| Lu, T | 1 |
| Tan, L | 1 |
| Xu, K | 1 |
| Liu, J | 3 |
| Liu, C | 1 |
| Zhang, G | 1 |
| Shi, R | 1 |
| Huang, Z | 1 |
| Rissel, R | 3 |
| Koelm, S | 3 |
| Schepers, M | 3 |
| Dohle, DS | 3 |
| Albers, J | 3 |
| Oezkur, M | 3 |
| Kriege, M | 3 |
| Bodenstein, M | 3 |
| Schneider, L | 3 |
| Chalmers, D | 3 |
| O'Beirn, S | 3 |
| Greenberg, M | 3 |
| Cave, G | 3 |
| Rezar, R | 1 |
| Mamandipoor, B | 1 |
| Seelmaier, C | 1 |
| Jung, C | 1 |
| Lichtenauer, M | 1 |
| Hoppe, UC | 1 |
| Kaufmann, R | 1 |
| Osmani, V | 1 |
| Wernly, B | 1 |
| Kim, SG | 1 |
| Lee, J | 1 |
| Yun, D | 1 |
| Kang, MW | 1 |
| Kim, YC | 2 |
| Kim, DK | 1 |
| Oh, KH | 1 |
| Joo, KW | 1 |
| Kim, YS | 1 |
| Han, SS | 1 |
| Yu, B | 1 |
| Park, CM | 1 |
| Gil, E | 1 |
| Yoo, K | 1 |
| Choi, KJ | 1 |
| Yoon, SJ | 1 |
| Han, IW | 1 |
| Sandal, ÖS | 1 |
| Ceylan, G | 1 |
| Sarı, F | 1 |
| Atakul, G | 1 |
| Çolak, M | 1 |
| Topal, S | 1 |
| Soydan, E | 1 |
| Karaarslan, ÜU | 1 |
| Ağın, H | 1 |
| Alshammary, AF | 1 |
| AlQarni, HM | 1 |
| Farzan, R | 1 |
| Ali Khan, I | 1 |
| Vennu, V | 1 |
| Kumar, A | 1 |
| Doola, R | 1 |
| Zahumensky, A | 1 |
| Shaikh, A | 1 |
| Tabah, A | 1 |
| Laupland, KB | 1 |
| Ramanan, M | 1 |
| Liu, W | 1 |
| Zhang, S | 1 |
| Li, Q | 1 |
| Wu, Y | 1 |
| Jia, X | 1 |
| Feng, W | 1 |
| Li, Z | 1 |
| Shi, Y | 2 |
| Hou, Q | 1 |
| Ma, J | 1 |
| Liu, Y | 1 |
| Gao, P | 1 |
| Ganz, T | 1 |
| Liu, S | 1 |
| Fitzgerald, O | 1 |
| Perez-Concha, O | 1 |
| Gallego-Luxan, B | 1 |
| Rudd, L | 1 |
| Jorm, L | 1 |
| Ma, S | 1 |
| Lee, H | 1 |
| Jo, WY | 1 |
| Byun, YH | 1 |
| Shin, KW | 1 |
| Choi, S | 1 |
| Oh, H | 1 |
| Park, CK | 1 |
| Park, HP | 1 |
| Guo, T | 1 |
| Zheng, R | 1 |
| Yi, H | 1 |
| Yang, Y | 1 |
| Borghi, F | 1 |
| Morais, CL | 1 |
| Silva, C | 1 |
| da Silva, PC | 1 |
| Ishizu, LY | 1 |
| Costa, GT | 1 |
| Grassi-Kassisse, DM | 1 |
| Wardi, G | 1 |
| Brice, J | 1 |
| Correia, M | 1 |
| Liu, D | 2 |
| Self, M | 1 |
| Tainter, C | 1 |
| Romano, D | 1 |
| Deiner, S | 1 |
| Cherukuri, A | 1 |
| Boateng, B | 1 |
| Shrivastava, R | 1 |
| Mocco, J | 1 |
| Hadjipanayis, C | 1 |
| Yong, R | 1 |
| Kellner, C | 1 |
| Yaeger, K | 1 |
| Lin, HM | 2 |
| Brallier, J | 1 |
| Gosmanova, EO | 1 |
| Shahzad, SR | 1 |
| Sumida, K | 1 |
| Kovesdy, CP | 1 |
| Gosmanov, AR | 1 |
| Hernández, G | 3 |
| Bakker, J | 4 |
| Lausch, CK | 1 |
| Lorch, A | 1 |
| Giertzuch, S | 1 |
| Rieger, A | 1 |
| Knubben-Schweizer, G | 1 |
| Trefz, FM | 1 |
| Stephens, EH | 1 |
| Epting, CL | 1 |
| Backer, CL | 1 |
| Wald, EL | 1 |
| Kędziora, A | 2 |
| Wierzbicki, K | 1 |
| Piątek, J | 1 |
| Hymczak, H | 2 |
| Górkiewicz-Kot, I | 1 |
| Milaniak, I | 1 |
| Tomsia, P | 1 |
| Sobczyk, D | 1 |
| Drwiła, R | 2 |
| Kapelak, B | 2 |
| Lawson, CA | 1 |
| Spangler, EA | 1 |
| Kramer, A | 1 |
| Al Agha, S | 1 |
| Böhm, L | 1 |
| Michael, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Medical Education for Sepsis Source Control and Antibiotics[NCT01187134] | 4,138 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| Using the ΔvapCO2 / Cav02 Ratio as a Prognostic Marker and Predictor of Complications After Cardiac Surgery[NCT02876406] | 150 participants (Anticipated) | Observational [Patient Registry] | 2016-10-31 | Recruiting | |||
| Mortality Due to Septic Shock Associated With Thrombocytopenia in the Intensive Care Unit[NCT03617965] | 350 participants (Anticipated) | Observational | 2018-08-15 | Active, not recruiting | |||
| Dexmedetomidine Improve Microcirculatory Alterations in Initial Resuscitated Septic Shock Patients[NCT02270281] | Phase 4 | 44 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| [NCT02566460] | 360 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Mean Arterial Pressure (MAP) Trial: Study Protocol for a Multicenter, Randomized, Controlled Trial to Compare Three Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass[NCT05740397] | 900 participants (Anticipated) | Interventional | 2021-05-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for lactic acid and Hyperlactatemia
| Article | Year |
|---|---|
What Is the Utility of Measuring Lactate Levels in Patients with Sepsis and Septic Shock?
Topics: Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis; Shock, Septic | 2021 |
Blood lactate concentration in COVID-19: a systematic literature review.
Topics: COVID-19; Hospitalization; Humans; Hyperlactatemia; Lactic Acid; SARS-CoV-2 | 2022 |
Demystifying Lactate in the Emergency Department.
Topics: Acidosis, Lactic; Emergency Service, Hospital; Humans; Hyperlactatemia; Lactic Acid; Prognosis; Seps | 2020 |
Hyperlactatemia: An Update on Postoperative Lactate.
Topics: Acidosis, Lactic; Biomarkers; Cardiac Surgical Procedures; Female; Humans; Hyperlactatemia; Hypoxia; | 2020 |
[Lactate in emergency medicine].
Topics: Emergency Medicine; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Shock | 2020 |
Blood lactate levels in sepsis: in 8 questions.
Topics: Critical Illness; Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis | 2021 |
Drug-induced hyperlactatemia.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Energy Metabolism; Humans; Hyperlactate | 2017 |
Clinical use of plasma lactate concentration. Part 1: Physiology, pathophysiology, and measurement.
Topics: Animals; Biomarkers; Humans; Hyperlactatemia; Lactic Acid | 2018 |
Clinical use of plasma lactate concentration. Part 2: Prognostic and diagnostic utility and the clinical management of hyperlactatemia.
Topics: Animals; Biomarkers; Humans; Hyperlactatemia; Lactic Acid; Species Specificity | 2018 |
Agreement between arterial and peripheral venous lactate levels in the ED: A systematic review.
Topics: Arteries; Emergency Service, Hospital; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Veins | 2019 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Sepsis-associated hyperlactatemia.
Topics: Animals; Cell Hypoxia; Humans; Hyperlactatemia; Lactic Acid; Oxygen Consumption; Sepsis | 2014 |
Lactic acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Fluid Therapy; Humans; Hyperlactatemia; Lactic Acid; Progno | 2014 |
Update: Clinical Use of Plasma Lactate.
Topics: Animals; Dog Diseases; Dogs; Humans; Hyperlactatemia; Lactic Acid; Prognosis; Reference Values | 2017 |
Hyperlactatemia and Cardiac Surgery.
Topics: Acidosis, Lactic; Biomarkers; Cardiac Surgical Procedures; Humans; Hyperlactatemia; Hypoxia; Lactic | 2017 |
6 trials available for lactic acid and Hyperlactatemia
| Article | Year |
|---|---|
Effects of norepinephrine infusion during cardiopulmonary bypass on perioperative changes in lactic acid level (Norcal).
Topics: Cardiopulmonary Bypass; Humans; Hyperlactatemia; Hypotension; Lactic Acid; Myocardial Ischemia; Nore | 2023 |
Continuous ultrafiltration during extracorporeal circulation and its effect on lactatemia: A randomized controlled trial.
Topics: Aged; Cardiac Surgical Procedures; Continuous Renal Replacement Therapy; Extracorporeal Circulation; | 2020 |
Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit.
Topics: Biomarkers; Child; Diabetic Ketoacidosis; Female; Follow-Up Studies; Humans; Hyperlactatemia; Intens | 2021 |
Early Lactate-Guided Resuscitation of Elderly Septic Patients.
Topics: Aged; Fluid Therapy; Humans; Hyperlactatemia; Lactic Acid; Resuscitation; Sepsis; Shock, Septic | 2022 |
Association of Clinical Hypoperfusion Variables With Lactate Clearance and Hospital Mortality.
Topics: Adult; Aged; Female; Hospital Mortality; Humans; Hyperlactatemia; Infections; Lactic Acid; Male; Mid | 2018 |
Use of stepwise lactate kinetics-oriented hemodynamic therapy could improve the clinical outcomes of patients with sepsis-associated hyperlactatemia.
Topics: Adult; Aged; Chi-Square Distribution; China; Female; Guidelines as Topic; Heart Rate; Hemodynamics; | 2017 |
100 other studies available for lactic acid and Hyperlactatemia
| Article | Year |
|---|---|
Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Humans; Hyperlactatemia; Intensive Care Units; Lactic Acid; R | 2022 |
Understanding critically ill sepsis patients with normal serum lactate levels: results from U.S. and European ICU cohorts.
Topics: Aged; Critical Illness; Europe; Female; Hospital Mortality; Humans; Hyperlactatemia; Intensive Care | 2021 |
Association Between Hyperlactatemia, Perfusional Parameters, and Lymphocyte Mitochondrial Dysfunction in Septic Shock Patients.
Topics: Aged; Female; Hemodynamics; Humans; Hyperlactatemia; Lactic Acid; Lymphocytes; Male; Middle Aged; Mi | 2022 |
Hyperlactatemia in diabetic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hyperglycemi | 2022 |
Acute Response to One Bout of Dynamic Standing Exercise on Blood Glucose and Blood Lactate Among Children and Adolescents With Cerebral Palsy Who are Nonambulant.
Topics: Adolescent; Blood Glucose; Cerebral Palsy; Child; Exercise; Humans; Hyperlactatemia; Lactic Acid | 2022 |
Duration of postoperative hyperlactatemia has predictive value in recurrent fistula after major definitive surgery for intestinal fistula.
Topics: Humans; Hyperlactatemia; Intestinal Fistula; Lactic Acid; Postoperative Period; Retrospective Studie | 2022 |
Hyperlactatemia as a Risk Stratification for Postinfarction Ventricular Septal Rupture.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Risk Assessment; Ventricular Septal Rup | 2022 |
Hyperlactatemia associated with elective tumor craniotomy: Protocol for an observational study of pathophysiology and clinical implications.
Topics: Brain Neoplasms; Craniotomy; Humans; Hyperlactatemia; Insulin Resistance; Lactic Acid; Observational | 2022 |
Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors.
Topics: Humans; Hyperlactatemia; Lactic Acid; Prognosis; Retrospective Studies; Sepsis; Shock, Hemorrhagic | 2022 |
Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose.
Topics: Adult; Cardiotoxicity; Cocaine; Drug Overdose; Emergency Service, Hospital; Ethanol; Heart Arrest; H | 2023 |
Risk Factors and Consequences of Late-Onset Hyperlactatemia After Cardiac Surgery With Cardiopulmonary Bypass: A Single-Center Retrospective Study.
Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Hyperlactatemia; Lactic Acid; Postopera | 2022 |
Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery.
Topics: Acidosis, Lactic; Analgesics, Opioid; Cardiac Surgical Procedures; Epinephrine; Heart Valves; Humans | 2022 |
Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study.
Topics: Acute Kidney Injury; Adult; Aged; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hy | 2022 |
Outcomes of hyperlactatemia on admission in critically ill patients with acute myocardial infarction: A retrospective study from MIMIC-IV.
Topics: Critical Illness; Heart Failure; Humans; Hyperlactatemia; Lactic Acid; Myocardial Infarction; Retros | 2022 |
Elevated lactate levels and impaired lactate clearance during extracorporeal life support (ECLS) are associated with poor outcome in cardiac surgery patients.
Topics: Cardiac Surgical Procedures; Extracorporeal Membrane Oxygenation; Humans; Hyperlactatemia; Lactic Ac | 2022 |
Elevated lactate levels and impaired lactate clearance during extracorporeal life support (ECLS) are associated with poor outcome in cardiac surgery patients.
Topics: Cardiac Surgical Procedures; Extracorporeal Membrane Oxygenation; Humans; Hyperlactatemia; Lactic Ac | 2022 |
Elevated lactate levels and impaired lactate clearance during extracorporeal life support (ECLS) are associated with poor outcome in cardiac surgery patients.
Topics: Cardiac Surgical Procedures; Extracorporeal Membrane Oxygenation; Humans; Hyperlactatemia; Lactic Ac | 2022 |
Elevated lactate levels and impaired lactate clearance during extracorporeal life support (ECLS) are associated with poor outcome in cardiac surgery patients.
Topics: Cardiac Surgical Procedures; Extracorporeal Membrane Oxygenation; Humans; Hyperlactatemia; Lactic Ac | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.
Topics: Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies; Sepsis; Shock, Septic | 2022 |
Hyperlactatemia and altered lactate kinetics are associated with excess mortality in sepsis : A multicenter retrospective observational study.
Topics: Humans; Hyperlactatemia; Kinetics; Lactic Acid; Retrospective Studies; Sepsis | 2023 |
Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury.
Topics: Acute Kidney Injury; APACHE; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hyperla | 2023 |
Clinical impact of lactate on postoperative pancreatic fistula after pancreaticoduodenectomy: A single-center retrospective study of 1,043 patients.
Topics: Humans; Hyperlactatemia; Lactic Acid; Pancreatic Fistula; Pancreaticoduodenectomy; Postoperative Com | 2023 |
Could lactate clearance be a marker of mortality in pediatric intensive care unit?
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Female; Humans; Hyperlactatemia; Intensive Care Uni | 2022 |
The risk of venous thromboembolism and blood hyperlactatemia is associated with increased mortality among critically ill patients with Covid-19.
Topics: Adolescent; Adult; COVID-19; Critical Illness; Humans; Hyperlactatemia; Intensive Care Units; Lactic | 2023 |
Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis.
Topics: Adult; Cohort Studies; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hyperlactatemia; Intensive | 2023 |
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Hepcidins; Humans; Hyperlactatemia; Iron; Lactic Acid; Mice | 2023 |
The relationship between hyperglycaemia on admission and patient outcome is modified by hyperlactatemia and diabetic status: a retrospective analysis of the eICU collaborative research database.
Topics: Blood Glucose; Diabetes Mellitus; Humans; Hyperglycemia; Hyperlactatemia; Lactic Acid; Retrospective | 2023 |
The Warburg effect in patients with brain tumors: a comprehensive analysis of clinical significance.
Topics: Brain Neoplasms; Clinical Relevance; Humans; Hyperlactatemia; Lactic Acid; Retrospective Studies | 2023 |
Association between initial microcirculation disturbance patients and mortality in patients who are critically ill: A retrospective cohort study.
Topics: Cohort Studies; Critical Illness; Hospital Mortality; Humans; Hyperlactatemia; Intensive Care Units; | 2023 |
A new perspective of lactatogenesis by isolated adipocytes.
Topics: Adipocytes; Animals; Body Weight; Fasting; Glucose; Hyperlactatemia; Hypertension; Lactic Acid; Male | 2019 |
Clinical impact of intraoperative hyperlactatemia during craniotomy.
Topics: Cohort Studies; Craniotomy; Female; Humans; Hyperlactatemia; Intraoperative Complications; Lactic Ac | 2019 |
Metformin is associated with increase in lactate level in elderly patients with type 2 diabetes and CKD stage 3: A case-control study.
Topics: Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neph | 2020 |
Perspectives on perfusion monitoring in septic shock after the ANDROMEDA-SHOCK trial.
Topics: Capillaries; Humans; Hyperlactatemia; Lactic Acid; Microcirculation; Multicenter Studies as Topic; P | 2019 |
Prognostic relevance of pre- and postoperative plasma l-lactate measurements in calves with acute abdominal emergencies.
Topics: Abdomen, Acute; Animals; Animals, Newborn; Cattle; Cattle Diseases; Emergencies; Female; Hyperlactat | 2020 |
Postoperative Serum Lactate Levels for In-Hospital Mortality Prediction Among Heart Transplant Recipients.
Topics: Adult; Critical Care; Female; Heart Failure; Heart Transplantation; Hospital Mortality; Humans; Hype | 2020 |
The effect of adding lactic acid to canine whole blood on platelet aggregation as measured by impedance aggregometry.
Topics: Animals; Blood Platelets; Dog Diseases; Dogs; Electric Impedance; Female; Hematocrit; Hemostasis; Hy | 2020 |
Peritonitis-associated hyperlactatemia for evaluating mortality in secondary peritonitis.
Topics: Humans; Hyperlactatemia; Lactic Acid; Peritonitis; Prognosis; Sepsis | 2020 |
Can multiple-dose activated charcoal induce elevation in blood lactate concentration? A case report.
Topics: Aged; Antidotes; Carbamazepine; Charcoal; Female; Humans; Hyperlactatemia; Intubation, Gastrointesti | 2021 |
Prognostic value of lactate levels and lactate clearance in sepsis and septic shock with initial hyperlactatemia: A retrospective cohort study according to the Sepsis-3 definitions.
Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Emergency Service, Hospital; Female; Huma | 2021 |
Prognostic role of perioperative acid-base disturbances on the risk of Clostridioides difficile infection in patients undergoing cardiac surgery.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Age Factors; Aged; Blood Gas Analysis; Cardiac Surgical | 2021 |
Significance of lactate clearance in septic shock patients with high bilirubin levels.
Topics: Aged; Bacterial Infections; Bilirubin; Female; Hospital Mortality; Humans; Hyperlactatemia; Lactic A | 2021 |
Admission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short- and long-term mortality risk.
Topics: Brain Ischemia; Hospital Mortality; Humans; Hyperlactatemia; Lactic Acid; Prognosis; Retrospective S | 2021 |
[Approach to diagnosis and treatment of hyperlactatemia].
Topics: Humans; Hyperlactatemia; Lactic Acid | 2021 |
Imaging Hyperpolarized Lactate in Prostate Cancer.
Topics: Humans; Hyperlactatemia; Lactic Acid; Magnetic Resonance Imaging; Male; Prostatic Neoplasms | 2019 |
The risk factors of intraoperative hyperlactatemia in patients undergoing laparoscopic colorectal surgery.
Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Female; Humans; Hyperlactatemia; Lactic Acid; | 2021 |
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis.
Topics: Animals; Glucocorticoids; Hyperlactatemia; Lactic Acid; Mice; Receptors, Glucocorticoid; Sepsis; Vas | 2021 |
Evolving cutoff values of "hyperlactatemia" and the role of infection.
Topics: Acidosis, Lactic; Humans; Hyperlactatemia; Lactic Acid; Sepsis; Shock, Septic | 2017 |
Lactate and Echocardiography Before Veno-Venous Extracorporeal Membrane Oxygenation Support.
Topics: Biomarkers; Echocardiography; Extracorporeal Membrane Oxygenation; Female; Humans; Hyperlactatemia; | 2018 |
The small-for-gestational-age fetus has an intact ability to develop lacticemia when exposed to hypoxia: a retrospective comparative register study.
Topics: Analysis of Variance; Biomarkers; Blood Glucose; Case-Control Studies; Female; Fetal Blood; Fetal Gr | 2018 |
Metformin Does Not Induce Hyperlactatemia in Patients Admitted to Internal Medicine Ward.
Topics: Acidosis, Lactic; Contraindications, Drug; Diabetes Mellitus; Hospitalization; Humans; Hyperlactatem | 2017 |
Hyperlactatemia, Lactate Kinetics and Prediction of Citrate Accumulation in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy With Regional Citrate Anticoagulation.
Topics: Anticoagulants; Citric Acid; Critical Illness; Hospitals, University; Humans; Hyperlactatemia; Inten | 2017 |
Hyperlactatemia in ICU patients: Incidence, causes and associated mortality.
Topics: Adult; Aged; Area Under Curve; Cardiac Surgical Procedures; Critical Illness; Female; Hospital Morta | 2017 |
Peripheral venoarterial extracorporeal membrane oxygenation for severe hyperlactataemia after cardiac surgery: a pilot study.
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Alanine Transaminase; Cardiac Surgical Procedures; Case-C | 2017 |
Risk factors for mortality in patients with low lactate level and septic shock.
Topics: Aged; APACHE; C-Reactive Protein; Chronic Disease; Cohort Studies; Female; Heart Failure; Humans; Hy | 2019 |
Skin perfusion pressure as an indicator of tissue perfusion in valvular heart surgery: Preliminary results from a prospective, observational study.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Cardiopulmonary Bypass; Female; Heart Valve Diseases; H | 2017 |
Prognostic Value of Hyperlactatemia and Lactate Clearance After Mitral Valve Surgery.
Topics: Aged; Biomarkers; Cardiac Surgical Procedures; Female; Humans; Hyperlactatemia; Lactic Acid; Length | 2018 |
Retrospective evaluation of the prognostic utility of plasma lactate concentration, base deficit, pH, and anion gap in canine and feline emergency patients.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Gas Analysis; Cat Diseases; Cats; Dog Diseases; Dogs | 2018 |
The Incidence, Risk Factors, and Outcomes of Hyperlactatemia after Heart Transplantation.
Topics: Adult; Female; Follow-Up Studies; Heart Transplantation; Humans; Hyperlactatemia; Incidence; Japan; | 2018 |
Hyperlactatemia and the Importance of Repeated Lactate Measurements in Critically Ill Patients.
Topics: Adult; Aged; Aged, 80 and over; Bosnia and Herzegovina; Critical Illness; Female; Hospital Mortality | 2017 |
[CLINICAL ASPECTS OF THE BLOOD LACTATE DYNAMICS DURING OPERATIONS ON THE HEART AND THE AORTA IN CONDITIONS OF CARDIOPULMONARY BYPASS.]
Topics: Aorta; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Hyperlactatemia; Lactic Acid; Mo | 2016 |
Perioperative Hyperlactemia Is a Poor Predictor of Outcome in Patients Undergoing Surgery for Acute Type-A Aortic Dissection.
Topics: Acute Disease; Aortic Aneurysm, Thoracic; Aortic Dissection; Biomarkers; Female; Follow-Up Studies; | 2018 |
The incidence and outcome of hyperlactatemia in patients admitted to the intensive care unit after elective surgery.
Topics: Aged; Critical Illness; Elective Surgical Procedures; Emergencies; Female; Follow-Up Studies; Hospit | 2018 |
Increase of Perfusion Index During Vascular Occlusion Test is Paradoxically Associated With Higher Mortality in Septic Shock After Fluid Resuscitation: A Prospective Study.
Topics: Aged; Blood Gas Monitoring, Transcutaneous; Female; Humans; Hyperlactatemia; Lactic Acid; Male; Micr | 2019 |
Blood lactate measurement within the emergency department: A two-year retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Emergency Service, Hospital; Female; France; Hospital Mo | 2019 |
Base excess is superior to lactate-levels in prediction of ICU mortality after cardiac surgery.
Topics: Aged; Cardiopulmonary Bypass; Female; Hospital Mortality; Humans; Hyperlactatemia; Hypertension, Pul | 2018 |
Incidence and risk factors for hyperlactatemia in ED patients with acute metformin overdose.
Topics: Acetaminophen; Acidosis, Lactic; Analgesics, Non-Narcotic; Case-Control Studies; Drug Overdose; Emer | 2019 |
Understanding Hyperlactatemia in Human Sepsis: Are We Making Progress?
Topics: Humans; Hyperlactatemia; Lactic Acid; Sepsis | 2019 |
Understanding Hyperlactatemia in Sepsis: Are We There Yet?
Topics: Humans; Hyperlactatemia; Lactic Acid; Sepsis | 2019 |
Prognostic value of serum lactate kinetics in critically ill patients with cirrhosis and acute-on-chronic liver failure: a multicenter study.
Topics: Acute-On-Chronic Liver Failure; Aged; Area Under Curve; Cohort Studies; Critical Illness; Female; Hu | 2019 |
Matched Retrospective Cohort Study of Thiamine to Treat Persistent Hyperlactatemia in Pediatric Septic Shock.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Female; Hospitals, Pediatric; Humans; Hyperlactatem | 2019 |
Blood lactate in HIV-infected children on antiretroviral therapy in rural South Africa.
Topics: Anti-Retroviral Agents; Child; Female; HIV Infections; Humans; Hyperlactatemia; Lactic Acid; Male; P | 2014 |
Association between hyperlactatemia and occult cardiac failure in diabetic patients on maintenance hemodialysis.
Topics: Aged; Bicarbonates; Blood Gas Analysis; Diabetic Nephropathies; Echocardiography; Female; Heart Fail | 2014 |
Metformin accumulation without hyperlactataemia and metformin-induced hyperlactataemia without metformin accumulation.
Topics: Acidosis, Lactic; Aged; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Hypersensitivi | 2014 |
Hyperlactemia induction modes affect the lactate minimum power and physiological responses in cycling.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Bicycling; Exercise Test; Humans; Hydrogen-Ion Concentration; | 2014 |
Hyperlactatemia is an independent predictor of mortality and denotes distinct subtypes of severe sepsis and septic shock.
Topics: Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Hyperlactatemia; Lactic Acid; Logistic Mode | 2015 |
Lactate in sepsis.
Topics: Aged; Fluid Therapy; Humans; Hyperlactatemia; Lactic Acid; Male; Sepsis; Water-Electrolyte Balance | 2015 |
Disease heterogeneity and risk stratification in sepsis-related occult hypoperfusion: A retrospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Emergency Service, Hospital; Female; Fluid Therapy; | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver; Liver Diseases; Metabolic Clearance Rate | 2015 |
The Use of the Ratio between the Veno-arterial Carbon Dioxide Difference and the Arterial-venous Oxygen Difference to Guide Resuscitation in Cardiac Surgery Patients with Hyperlactatemia and Normal Central Venous Oxygen Saturation.
Topics: Adult; Aged; Blood Gas Analysis; Carbon Dioxide; Cardiac Surgical Procedures; Female; Humans; Hyperl | 2015 |
Is there an association between body temperature and serum lactate levels in hip fracture patients?
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Body Temperature; Female; Fever; Hip Fractures; Humans; | 2015 |
Is lactate clearance impaired in septic shock?
Topics: Animals; Hemodynamics; Hyperlactatemia; Lactic Acid; Liver Diseases; Metabolic Clearance Rate; Shock | 2015 |
Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients.
Topics: Aged; Cohort Studies; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Hyperlact | 2016 |
Relationship Between Peak Lactate and Patient Outcome Following High-Risk Gastrointestinal Surgery: Influence of the Nature of Their Surgery: Elective Versus Emergency.
Topics: Aged; Aged, 80 and over; Critical Illness; Digestive System Surgical Procedures; Elective Surgical P | 2016 |
Lactate and adrenergic signalling in trauma.
Topics: Body Temperature; Female; Fever; Hip Fractures; Humans; Hyperlactatemia; Hypothermia; Lactic Acid; M | 2016 |
Physiological responses at the lactate-minimum-intensity with and without prior high-intensity exercise.
Topics: Adult; Anaerobic Threshold; Carbon Dioxide; Exercise; Exercise Test; Fatigue; Heart Rate; Humans; Hy | 2016 |
[Analysis of risk factor of hyperlactacidemia after gastrointestinal surgery: a clinical data analysis of 216 patients].
Topics: Anti-Bacterial Agents; Arterial Pressure; Calcitonin; Calcitonin Gene-Related Peptide; Digestive Sys | 2015 |
Hyperlactatemia and serial lactate measurements in sick cats.
Topics: Animals; Cat Diseases; Cats; Critical Illness; Female; Hospitalization; Hyperlactatemia; Lactic Acid | 2016 |
Authors' response.
Topics: Body Temperature; Female; Fever; Hip Fractures; Humans; Hyperlactatemia; Hypothermia; Lactic Acid; M | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Ani | 2016 |
Getting Burned by Lactic Acid.
Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Humans; Hyperlactatemia; Lactic Acid; Male; Unnecessar | 2016 |
Hyperlactemia Predicts Surgical Mortality in Patients Presenting With Acute Stanford Type-A Aortic Dissection.
Topics: Acute Disease; Aged; Aortic Aneurysm; Aortic Dissection; Biomarkers; Female; Hospital Mortality; Hum | 2017 |
Use of Postoperative Peak Arterial Lactate Level to Predict Outcome After Cardiac Surgery.
Topics: Aged; Biomarkers; Cardiac Surgical Procedures; Female; Follow-Up Studies; Humans; Hyperlactatemia; K | 2017 |
Continuous Monitoring of Lactate Using Intravascular Microdialysis in High-Risk Cardiac Surgery: A Prospective Observational Study.
Topics: Aged; Cardiac Surgical Procedures; Catheterization, Central Venous; Female; Humans; Hyperlactatemia; | 2017 |
A Patient With Alcoholic Ketoacidosis and Profound Lactemia.
Topics: Acid-Base Equilibrium; Alcoholism; Fluid Therapy; Glucose; Humans; Hyperlactatemia; Ketosis; Lactic | 2016 |
Investigation of Risk Factors Affecting Lactate Levels in Japanese Patients Treated with Metformin.
Topics: Adult; Aged; Asian People; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Type 2; Female; Glyca | 2016 |
Septic shock without hyperlactatemia.
Topics: Amputation, Surgical; Fatal Outcome; Female; Humans; Hyperlactatemia; Lactic Acid; Middle Aged; Shoc | 2017 |
Lactate minimum underestimates the maximal lactate steady-state in swimming mice.
Topics: Anaerobic Threshold; Animals; Body Weight; Exercise Test; Exercise Tolerance; Fatigue; Female; Hyper | 2017 |
Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes.
Topics: Acidosis, Lactic; Adult; Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; H | 2017 |
Early sepsis bundle compliance for non-hypotensive patients with intermediate versus severe hyperlactemia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Databases, Factual; Female; Hospital Mortality; Huma | 2017 |
Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department.
Topics: Aged; Aged, 80 and over; Comorbidity; Diabetes Mellitus; Emergency Service, Hospital; Female; Hospit | 2017 |
Impact of Epinephrine Contained in Local Anesthetic Solution on Serum Lactate Level During Orthognathic Surgery.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Epinephrine; Female; Humans; Hyperlactatemia; Intr | 2017 |
[Relationship of hyperlactatemia and metabolic acidosis].
Topics: Acidosis; Anions; Blood Gas Analysis; Humans; Hyperlactatemia; Intensive Care Units; Lactic Acid | 2011 |
Abnormal resting blood lactate. I. The significance of hyperlactatemia in hospitalized patients.
Topics: Acidosis; Humans; Hyperlactatemia; Lactates; Lactic Acid | 1961 |