Page last updated: 2024-10-17

lactic acid and Hyperkalemia

lactic acid has been researched along with Hyperkalemia in 19 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To determine the influence of lactic acidosis, the Bohr effect, and exercise induced hyperkalaemia on the occurrence of the heart rate deflection point (HRDP) in elite (professional) cyclists."9.10Lactic acidosis, potassium, and the heart rate deflection point in professional road cyclists. ( Carvajal, A; Chicharro, JL; Hoyos, J; Lucía, A; Pérez, M; Santalla, A, 2002)
" Intensive exercise also increases the level of circulating catecholamines and lactic acid, which both have been shown to alleviate the depressing effect of hyperkalemia in slow-twitch muscles."7.73Effects of lactic acid and catecholamines on contractility in fast-twitch muscles exposed to hyperkalemia. ( Clausen, T; Hansen, AK; Nielsen, OB, 2005)
"To determine the influence of lactic acidosis, the Bohr effect, and exercise induced hyperkalaemia on the occurrence of the heart rate deflection point (HRDP) in elite (professional) cyclists."5.10Lactic acidosis, potassium, and the heart rate deflection point in professional road cyclists. ( Carvajal, A; Chicharro, JL; Hoyos, J; Lucía, A; Pérez, M; Santalla, A, 2002)
" Intensive exercise also increases the level of circulating catecholamines and lactic acid, which both have been shown to alleviate the depressing effect of hyperkalemia in slow-twitch muscles."3.73Effects of lactic acid and catecholamines on contractility in fast-twitch muscles exposed to hyperkalemia. ( Clausen, T; Hansen, AK; Nielsen, OB, 2005)
" The principal findings included metabolic acidosis accompanied by an increase in the plasma anion gap that was not caused by L -lactic acidosis, hyperkalemia, and the abrupt onset of hypotension."3.71Citric acid ingestion: a life-threatening cause of metabolic acidosis. ( DeMars, CS; Halperin, ML; Himmelfarb, J; Hollister, K; Tomassoni, A, 2001)
" After propranolol, CaCl2 was given during acidosis and hyperkalemia."3.69Role of Ca2+ in protecting the heart from hyperkalemia and acidosis in the rabbit: implications for exercise. ( Leitch, SP; Paterson, DJ, 1994)
"Hemorrhagic shock was induced for 30 minutes while a leg compression device was applied."1.51Extracorporeal potassium binding for the management of hyperkalemia in an anephric model of crush injury. ( Beyer, CA; Grayson, JK; Hoareau, GL; Kashtan, H; Ross, JD; Stewart, IJ; Walker, L; Wilson, C; Wishy, A, 2019)
"Hyperkalemia is a clinically important electrolyte imbalance in neonatal diarrheic calves that has previously been associated with skeletal muscle weakness and life-threatening cardiac arrhythmias."1.39Hyperkalemia in neonatal diarrheic calves depends on the degree of dehydration and the cause of the metabolic acidosis but does not require the presence of acidemia. ( Constable, PD; Knubben-Schweizer, G; Lorch, A; Lorenz, I; Sauter-Louis, C; Trefz, FM, 2013)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's4 (21.05)18.2507
2000's6 (31.58)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Fenu, EM1
O'Neill, SS1
Insuasti-Beltran, G1
Pettenati, MJ1
Giffen, M1
Harrison, WT1
Hoareau, GL1
Beyer, CA1
Wilson, C1
Kashtan, H1
Wishy, A1
Grayson, JK1
Walker, L1
Ross, JD1
Stewart, IJ1
Delaney, M1
Axdorff-Dickey, RL1
Crockett, GI1
Falconer, AL1
Levario, MJ1
McMullan, DM1
Trefz, FM1
Constable, PD1
Sauter-Louis, C1
Lorch, A1
Knubben-Schweizer, G1
Lorenz, I1
Ho, JD1
Dawes, DM1
Bultman, LL1
Moscati, RM1
Janchar, TA1
Miner, JR1
Jauchem, JR1
Cheema-Dhadli, S1
Chong, CK1
Kamel, KS1
Halperin, ML2
Medeiros, WM1
Carvalho, AC1
Peres, P1
De Luca, FA1
Gun, C1
Zouaoui, K1
Dulaurent, S1
Gaulier, JM1
Moesch, C1
Lachâtre, G1
Hansen, AK1
Clausen, T1
Nielsen, OB1
Reinert, M1
Khaldi, A1
Zauner, A1
Doppenberg, E1
Choi, S1
Bullock, R1
Leitch, SP1
Paterson, DJ1
Chin, ER1
Lindinger, MI1
Heigenhauser, GJ1
Bøtker, HE1
Sonne, HS1
Frøbert, O1
Andreasen, F1
Nakasuji, M1
Bookallil, MJ1
DeMars, CS1
Hollister, K1
Tomassoni, A1
Himmelfarb, J1
Lucía, A1
Hoyos, J1
Santalla, A1
Pérez, M1
Carvajal, A1
Chicharro, JL1
Banker, MC1
Hicks, GL1
Tibi, P1
Pearce, F1
Rosenmund, A1
Brand, B1
Straub, PW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pre Bypass Ultrafiltration (PBUF) Improves Intraoperative Glucose, Sodium, Potassium and Lactate Levels in Children Requiring Cardiopulmonary Bypass[NCT03576534]13 participants (Actual)Interventional2019-10-03Terminated (stopped due to Given SARS CoV2 pandemic, we had difficulty enrolling patients in the proposed time frame)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lactic acid and Hyperkalemia

ArticleYear
Pathophysiologic changes due to TASER® devices versus excited delirium: potential relevance to deaths-in-custody?
    Journal of forensic and legal medicine, 2011, Volume: 18, Issue:4

    Topics: Acidosis; Animals; Blood Glucose; Body Temperature; Catecholamines; Channelopathies; Conducted Energ

2011

Trials

5 trials available for lactic acid and Hyperkalemia

ArticleYear
Risk of extracorporeal life support circuit-related hyperkalemia is reduced by prebypass ultrafiltration.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013, Volume: 14, Issue:6

    Topics: Adolescent; Biomarkers; Child; Child, Preschool; Erythrocyte Transfusion; Extracorporeal Circulation

2013
Prolonged TASER use on exhausted humans does not worsen markers of acidosis.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:4

    Topics: Acidosis; Adult; Biomarkers; Electric Injuries; Electric Stimulation; Electroshock; Fatigue; Female;

2009
The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy.
    European journal of preventive cardiology, 2014, Volume: 21, Issue:2

    Topics: Adult; Ammonia; Biomarkers; Brazil; Cardiovascular Agents; Cross-Over Studies; Heart Failure; Humans

2014
Pathophysiological mechanisms of postrevascularization hyperkalemia in orthotopic liver transplantation.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:6

    Topics: Adult; Aspartate Aminotransferases; Blood Loss, Surgical; Central Venous Pressure; Female; Humans; H

2000
Lactic acidosis, potassium, and the heart rate deflection point in professional road cyclists.
    British journal of sports medicine, 2002, Volume: 36, Issue:2

    Topics: Acidosis, Lactic; Adult; Anaerobic Threshold; Bicycling; Exercise; Exercise Test; Heart Rate; Humans

2002

Other Studies

13 other studies available for lactic acid and Hyperkalemia

ArticleYear
Sudden Unexpected Death in a Child From Acute Myeloid Leukemia.
    The American journal of forensic medicine and pathology, 2021, Jun-01, Volume: 42, Issue:2

    Topics: Acidosis; Anemia; Child, Preschool; Death, Sudden; Female; Gene Rearrangement; Histone-Lysine N-Meth

2021
Extracorporeal potassium binding for the management of hyperkalemia in an anephric model of crush injury.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:4

    Topics: Animals; Crush Injuries; Disease Models, Animal; Extracorporeal Circulation; Female; Hyperkalemia; K

2019
Hyperkalemia in neonatal diarrheic calves depends on the degree of dehydration and the cause of the metabolic acidosis but does not require the presence of acidemia.
    Journal of dairy science, 2013, Volume: 96, Issue:11

    Topics: Acidosis; Animals; Cattle; Cattle Diseases; Creatinine; Dehydration; Diarrhea; Hydrogen-Ion Concentr

2013
An acute infusion of lactic acid lowers the concentration of potassium in arterial plasma by inducing a shift of potassium into cells of the liver in fed rats.
    Nephron. Physiology, 2012, Volume: 120, Issue:2

    Topics: Acute Disease; Animals; Hormones; Hydrochloric Acid; Hyperkalemia; Infusions, Intravenous; Insulin;

2012
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro

2013
Effects of lactic acid and catecholamines on contractility in fast-twitch muscles exposed to hyperkalemia.
    American journal of physiology. Cell physiology, 2005, Volume: 289, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Calcitonin Gene-Related Peptide; Epinephrine; Female;

2005
High extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure.
    Neurosurgical focus, 2000, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Astrocytes; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cran

2000
Role of Ca2+ in protecting the heart from hyperkalemia and acidosis in the rabbit: implications for exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:5

    Topics: Acidosis; Analysis of Variance; Animals; Calcium; Calcium Chloride; Female; Heart; Hemodynamics; Hyd

1994
Distribution of lactate and other ions in inactive skeletal muscle: influence of hyperkalemic lactacidosis.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:12

    Topics: Acidosis, Lactic; Animals; Hyperkalemia; Ion Transport; Lactic Acid; Male; Membrane Potentials; Musc

1997
Enhanced exercise-induced hyperkalemia in patients with syndrome X.
    Journal of the American College of Cardiology, 1999, Mar-15, Volume: 33, Issue:4

    Topics: Exercise Test; Female; Humans; Hyperkalemia; Lactic Acid; Male; Microvascular Angina; Middle Aged; M

1999
Citric acid ingestion: a life-threatening cause of metabolic acidosis.
    Annals of emergency medicine, 2001, Volume: 38, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Calcium; Calcium Chloride; Citric Acid; Critical Care; Drug

2001
Metabolic and functional cardiac impairment after reperfusion with persantine.
    The Journal of surgical research, 1991, Volume: 51, Issue:2

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Dipyridamole; Heart; Heart Arrest; Hemodynami

1991
Hyperlactataemia, hyperkalemia and heart block in acute iron overload: the fatal role of the hepatic iron-incorporation rate in rats on ferric citrate infusions.
    European journal of clinical investigation, 1988, Volume: 18, Issue:1

    Topics: Animals; Disease Models, Animal; Electrocardiography; Ferric Compounds; Heart Block; Heart Conductio

1988