lactic acid has been researched along with Hibernation, Myocardial in 23 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Short-term myocardial hibernation is characterized by an adaptation of contractile function to the reduced blood flow, the recovery of creatine phosphate content and lactate balance back towards normal, whereas ATP content remains reduced at a constant level." | 1.30 | Inorganic phosphate content and free energy change of ATP hydrolysis in regional short-term hibernating myocardium. ( Heusch, G; Martin, C; Rose, J; Schulz, R, 1998) |
| "Myocardial hibernation is an adaptive phenomenon occurring in patients with a history of acute ischemia followed by prolonged hypoperfusion." | 1.29 | Metabolic adaptation during a sequence of no-flow and low-flow ischemia. A possible trigger for hibernation. ( Bernocchi, P; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Ruigrok, TJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (56.52) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, Q | 1 |
| Suzuki, G | 1 |
| Young, RF | 1 |
| Page, BJ | 1 |
| Fallavollita, JA | 2 |
| Canty, JM | 2 |
| Malm, BJ | 1 |
| Southworth, R | 1 |
| Garlick, PB | 1 |
| Wiggers, H | 1 |
| Nørrelund, H | 1 |
| Nielsen, SS | 1 |
| Andersen, NH | 1 |
| Nielsen-Kudsk, JE | 1 |
| Christiansen, JS | 1 |
| Nielsen, TT | 1 |
| Møller, N | 1 |
| Bøtker, HE | 1 |
| Sidi, A | 2 |
| Muehlschlegel, JD | 2 |
| Muehschlegel, JD | 1 |
| Kirby, DS | 2 |
| Lobato, EB | 2 |
| Abd-Elfattah, AS | 1 |
| Wechsler, AS | 1 |
| Gao, ZP | 1 |
| Downey, HF | 1 |
| Fan, WL | 1 |
| Mallet, RT | 1 |
| Carrier, M | 1 |
| Tourigny, A | 1 |
| Thoribé, N | 1 |
| Montpetit, M | 1 |
| Khalil, A | 1 |
| Solymoss, BC | 1 |
| Pelletier, LC | 1 |
| Stahl, RF | 1 |
| Soller, BR | 1 |
| Hsi, C | 1 |
| BelleIsle, J | 1 |
| Vander Salm, TJ | 1 |
| Hata, K | 1 |
| Takasago, T | 1 |
| Saeki, A | 1 |
| Nishioka, T | 1 |
| Goto, Y | 1 |
| Okuda, K | 1 |
| Nohara, R | 1 |
| Fujita, M | 1 |
| Tamaki, N | 1 |
| Konishi, J | 1 |
| Sasayama, S | 1 |
| Ferrari, R | 1 |
| Cargnoni, A | 1 |
| Bernocchi, P | 1 |
| Pasini, E | 1 |
| Curello, S | 1 |
| Ceconi, C | 1 |
| Ruigrok, TJ | 1 |
| Sommerschild, HT | 2 |
| Offstad, J | 2 |
| Grund, F | 2 |
| Ilebekk, A | 2 |
| Kirkebøen, KA | 2 |
| McFalls, EO | 1 |
| Baldwin, D | 1 |
| Marx, D | 1 |
| Jaimes, D | 1 |
| Fashingbauer, P | 1 |
| Ward, HB | 1 |
| Martin, C | 1 |
| Schulz, R | 3 |
| Rose, J | 1 |
| Heusch, G | 3 |
| Dörge, H | 1 |
| Bartling, B | 1 |
| Hoffmann, J | 1 |
| Holtz, J | 1 |
| Darmer, D | 1 |
| Abete, P | 1 |
| Cioppa, A | 1 |
| Calabrese, C | 1 |
| Pascucci, I | 1 |
| Cacciatore, F | 1 |
| Napoli, C | 1 |
| Carnovale, V | 1 |
| Ferrara, N | 1 |
| Rengo, F | 1 |
| Kamel, KS | 1 |
| Mazer, CD | 1 |
| Nikolaidis, LA | 1 |
| Hentosz, T | 1 |
| Doverspike, A | 1 |
| Huerbin, R | 1 |
| Stolarski, C | 1 |
| Shen, YT | 1 |
| Shannon, RP | 1 |
| Korvald, C | 1 |
| Elvenes, OP | 1 |
| Aghajani, E | 1 |
| Myhre, ES | 1 |
| Myrmel, T | 1 |
2 reviews available for lactic acid and Hibernation, Myocardial
| Article | Year |
|---|---|
Myocardial preconditioning: a model or a phenomenon?
Topics: Adenosine Triphosphate; Animals; Heat-Shock Response; Humans; Lactates; Lactic Acid; Myocardial Isch | 1995 |
Pathophysiology of hibernation, stunning, and ischemic preconditioning.
Topics: Animals; Chronic Disease; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Stun | 1998 |
1 trial available for lactic acid and Hibernation, Myocardial
| Article | Year |
|---|---|
Influence of insulin and free fatty acids on contractile function in patients with chronically stunned and hibernating myocardium.
Topics: Aged; Blood Glucose; Chronic Disease; Cicatrix; Cross-Over Studies; Diastole; Drug Combinations; Ech | 2005 |
20 other studies available for lactic acid and Hibernation, Myocardial
| Article | Year |
|---|---|
Reductions in mitochondrial O(2) consumption and preservation of high-energy phosphate levels after simulated ischemia in chronic hibernating myocardium.
Topics: Adenosine Triphosphate; Animals; Chronic Disease; Coronary Circulation; Coronary Occlusion; Coronary | 2009 |
Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest.
Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Animals; Blood Flow Velocity; Blood Pressure; C | 2003 |
Dobutamine responsiveness, PET mismatch, and lack of necrosis in low-flow ischemia: is this hibernation in the isolated rat heart?
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Creatine Kinase; Dobutamine; Fluorodeoxyglucose F | 2003 |
Treating metabolic impairment and myocardial stunning with phosphodiesterase inhibitor type III, milrinone, administered prior to coronary artery occlusion in the presence of calcium channel blockade in pigs.
Topics: Analysis of Variance; Animals; Biomarkers; Blood Pressure; Calcium Channel Blockers; Cardiac Output; | 2007 |
Administration of milrinone before ischemia, in the presence of beta-blockade, to treat metabolic impairment and myocardial stunning in pigs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary S | 2008 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; C | 1995 |
Effects of cold and warm blood cardioplegia assessed by myocardial pH and release of metabolic markers.
Topics: Analysis of Variance; Animals; Biomarkers; Creatine Kinase; Dogs; Heart Arrest, Induced; Hydrogen-Io | 1994 |
Decreasing myocardial pH reflects ischemia during continuous warm retrograde cardioplegic arrest.
Topics: Adenosine Triphosphate; Animals; Cardioplegic Solutions; Dogs; Heart Arrest, Induced; Hydrogen-Ion C | 1994 |
Stunned myocardium after rapid correction of acidosis. Increased oxygen cost of contractility and the role of the Na(+)-H+ exchange system.
Topics: Acidosis; Animals; Calcium; Dogs; Epinephrine; Lactates; Lactic Acid; Myocardial Contraction; Myocar | 1994 |
Improvement of myocardial ischemic dysfunction with dichloroacetic acid: experimental study by repeated ischemia in dogs.
Topics: Animals; Blood Glucose; Calcium; Coronary Circulation; Dichloroacetic Acid; Dogs; Fatty Acids, Nones | 1995 |
Metabolic adaptation during a sequence of no-flow and low-flow ischemia. A possible trigger for hibernation.
Topics: Adaptation, Physiological; Animals; Biomechanical Phenomena; Calcium; Coronary Circulation; Creatine | 1996 |
Characterization of metabolic responses to low-flow ischemia in intact pig hearts and isolated blood-perfused neonatal pig hearts.
Topics: Adaptation, Physiological; Anaerobic Threshold; Animals; Animals, Newborn; Blood Flow Velocity; Carb | 1998 |
Adenosine receptor blockade enhances myocardial stunning without a sustained effect on fluorine-18-FDG uptake postreperfusion.
Topics: Animals; Coronary Circulation; Fluorodeoxyglucose F18; Glucose; Hemodynamics; Lactic Acid; Myocardia | 1998 |
Inorganic phosphate content and free energy change of ATP hydrolysis in regional short-term hibernating myocardium.
Topics: Adenosine Triphosphate; Animals; Biopsy; Cardiac Pacing, Artificial; Cardiotonic Agents; Coronary Ci | 1998 |
Quantification of cardioprotective gene expression in porcine short-term hibernating myocardium.
Topics: Amino Acid Sequence; Animals; Base Sequence; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Prote | 1999 |
Ischemic threshold and myocardial stunning in the aging heart.
Topics: Aging; Animals; Creatine Kinase; Heart; In Vitro Techniques; Lactic Acid; Male; Myocardial Stunning; | 1999 |
Importance of heart rate for acute hibernation in isolated blood-perfused piglet hearts.
Topics: Acute Disease; Animals; Biopsy; Creatine Kinase; Heart Rate; In Vitro Techniques; Lactic Acid; Myoca | 2000 |
Effect of NaHCO3 on cardiac energy metabolism and contractile function during hypoxemia.
Topics: Acidosis, Lactic; Analysis of Variance; Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; D | 2001 |
Mechanisms whereby rapid RV pacing causes LV dysfunction: perfusion-contraction matching and NO.
Topics: Animals; Cell Respiration; Consciousness; Coronary Circulation; Dogs; Enzyme Inhibitors; Female; Gly | 2001 |
Postischemic mechanoenergetic inefficiency is related to contractile dysfunction and not altered metabolism.
Topics: Animals; Blood Glucose; Blood Pressure; Carbon Radioisotopes; Energy Metabolism; Fatty Acids; Glucos | 2001 |