Page last updated: 2024-10-17

lactic acid and Hepatitis B

lactic acid has been researched along with Hepatitis B in 13 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Hepatitis B: INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.

Research Excerpts

ExcerptRelevanceReference
" In contrast, in Himalayan marmots treated with AZT we observed delayed toxicity, including lactic acidosis, severe hepatic steatosis, obvious mitochondrial damage, and significant decreases in respiratory chain complex enzyme activity and mtDNA content."7.77Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus. ( Chen, H; Hu, M; Jiang, Z; Li, Z; Tao, Y; Xiong, Y; Zhang, L; Zhang, P, 2011)
"Poly (L-lactic acid) (PLA) microparticles encapsulating Hepatitis B surface antigen (HBsAg) with alum and chitosan were investigated for their potential as a vaccine delivery system."7.74Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan. ( Alpar, HO; Cevher, E; Pandit, S; Somavarapu, S; Zariwala, MG, 2007)
" In contrast, in Himalayan marmots treated with AZT we observed delayed toxicity, including lactic acidosis, severe hepatic steatosis, obvious mitochondrial damage, and significant decreases in respiratory chain complex enzyme activity and mtDNA content."3.77Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus. ( Chen, H; Hu, M; Jiang, Z; Li, Z; Tao, Y; Xiong, Y; Zhang, L; Zhang, P, 2011)
"Poly (L-lactic acid) (PLA) microparticles encapsulating Hepatitis B surface antigen (HBsAg) with alum and chitosan were investigated for their potential as a vaccine delivery system."3.74Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan. ( Alpar, HO; Cevher, E; Pandit, S; Somavarapu, S; Zariwala, MG, 2007)
"The most common causes of ALF were indeterminate liver failure (21%), acute hepatitis B (18%), acetaminophen ingestion (16%), and Budd-Chiari syndrome (9%)."3.74Prognostic implications of lactate, bilirubin, and etiology in German patients with acute liver failure. ( Bahr, MJ; Hadem, J; Klempnauer, J; Manns, MP; Rifai, K; Schneider, AS; Stiefel, P; Tillmann, HL; Wedemeyer, H, 2008)
"Acute liver failure is often accompanied by hyperdynamic circulation, which is also a characteristic of septic shock."1.35Hemodynamics and metabolic studies on septic shock in patients with acute liver failure. ( Chen, PC; Chen, YC; Chu, YY; Fang, JT; Lien, JM; Peng, YS; Tang, JH; Tian, YC; Tsai, MH; Wu, CS; Yang, C, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Mohammed, MM1
Naif, HM1
Nie, Y1
Liu, LX1
Chen, T1
Zhang, Y2
Zhu, X1
Tsai, MH1
Chen, YC1
Lien, JM1
Tian, YC1
Peng, YS1
Fang, JT1
Yang, C1
Tang, JH1
Chu, YY1
Chen, PC1
Wu, CS1
Jain, AK1
Goyal, AK1
Gupta, PN1
Khatri, K1
Mishra, N1
Mehta, A1
Mangal, S1
Vyas, SP1
Zhang, P1
Zhang, L1
Jiang, Z1
Xiong, Y1
Chen, H1
Tao, Y1
Hu, M1
Li, Z1
Giri, N1
Tomar, P1
Karwasara, VS1
Pandey, RS1
Dixit, VK1
van de Kerkhove, MP1
Di Florio, E1
Scuderi, V1
Mancini, A1
Belli, A1
Bracco, A1
Scala, D1
Scala, S1
Zeuli, L1
Di Nicuolo, G1
Amoroso, P1
Calise, F1
Chamuleau, RA1
He, X1
Jiang, L1
Wang, F1
Xiao, Z1
Li, J1
Liu, LS1
Li, D1
Ren, D1
Jin, X1
Li, K1
He, Y1
Shi, K1
Guo, Y1
Sun, S1
Pandit, S1
Cevher, E1
Zariwala, MG1
Somavarapu, S1
Alpar, HO1
Hadem, J1
Stiefel, P1
Bahr, MJ1
Tillmann, HL1
Rifai, K1
Klempnauer, J1
Wedemeyer, H1
Manns, MP1
Schneider, AS1
Lee, MY1
Wang, SS1
Lu, CW1
Chao, Y1
Lee, FY1
Wu, SL1
Lee, SD1
Tsai, YT1
Lo, KJ1
Cui, L1
Schinazi, RF1
Gosselin, G1
Imbach, JL1
Chu, CK1
Rando, RF1
Revankar, GR1
Sommadossi, JP1
Moynihan, JS1
Jones, DH1
Farrar, GH1
Howard, CR1

Trials

1 trial available for lactic acid and Hepatitis B

ArticleYear
Bridging a patient with acute liver failure to liver transplantation by the AMC-bioartificial liver.
    Cell transplantation, 2003, Volume: 12, Issue:6

    Topics: Adult; Ammonia; Animals; Bilirubin; Female; Hepatitis B; Hepatocytes; Humans; Lactic Acid; Liver Fai

2003

Other Studies

12 other studies available for lactic acid and Hepatitis B

ArticleYear
Poly(Lactide-
    Viral immunology, 2022, Volume: 35, Issue:2

    Topics: Adjuvants, Immunologic; Antigens, Surface; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; Hum

2022
Serum lactate level predicts 6-months mortality in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective study.
    Epidemiology and infection, 2021, 01-05, Volume: 149

    Topics: Aged; Ascites; Carcinoma, Hepatocellular; Female; gamma-Glutamyltransferase; Hepatitis B; Hepatitis

2021
Hemodynamics and metabolic studies on septic shock in patients with acute liver failure.
    Journal of critical care, 2008, Volume: 23, Issue:4

    Topics: Aldosterone; APACHE; Blood Gas Analysis; Female; Hemodynamics; Hepatitis B; Hospital Mortality; Huma

2008
Synthesis, characterization and evaluation of novel triblock copolymer based nanoparticles for vaccine delivery against hepatitis B.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Jun-05, Volume: 136, Issue:2

    Topics: Animals; Drug Delivery Systems; Female; Hepatitis B; Hepatitis B Vaccines; Lactic Acid; Mice; Mice,

2009
Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5

    Topics: Acidosis, Lactic; Animals; Antiviral Agents; Dideoxynucleosides; DNA, Mitochondrial; Fatty Liver; He

2011
Targeted novel surface-modified nanoparticles for interferon delivery for the treatment of hepatitis B.
    Acta biochimica et biophysica Sinica, 2011, Volume: 43, Issue:11

    Topics: Animals; Drug Delivery Systems; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Interfero

2011
Augmented humoral and cellular immune responses to hepatitis B DNA vaccine adsorbed onto cationic microparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Oct-03, Volume: 107, Issue:2

    Topics: Adsorption; Animals; Antibody Formation; Blotting, Western; Cations; CD4-Positive T-Lymphocytes; CD8

2005
Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan.
    Journal of microencapsulation, 2007, Volume: 24, Issue:6

    Topics: Aluminum Hydroxide; Animals; Capsules; Cells, Cultured; Chitosan; Cytokines; Drug Carriers; Hepatiti

2007
Prognostic implications of lactate, bilirubin, and etiology in German patients with acute liver failure.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Bilirubin; Biomarkers; Budd-Chiari

2008
Diagnostic parameters for spontaneous bacterial peritonitis in hepatitis B-related cirrhosis: comparison of ascitic fluid polymorphonuclear cell count, lactate and pH values.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1994, Volume: 53, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ascitic Fluid; Bacterial Infections; Female; Hepatitis B; Humans; Hy

1994
Effect of beta-enantiomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implications for predicting drug hepatotoxicity.
    Biochemical pharmacology, 1996, Nov-22, Volume: 52, Issue:10

    Topics: Antiviral Agents; Cell Division; Cell Line; DNA, Mitochondrial; Drug Evaluation, Preclinical; Hepati

1996
A novel microencapsulated peptide vaccine against hepatitis B.
    Vaccine, 2001, Apr-30, Volume: 19, Issue:23-24

    Topics: Amino Acid Sequence; Animals; Capsules; Female; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Sur

2001