lactic acid has been researched along with Hemorrhage in 100 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy." | 7.79 | The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013) |
| "These findings support the possible beneficial effects of sabiporide in the treatment of acute metabolic acidosis and could have implications for the treatment of metabolic acidosis in man." | 7.79 | Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. ( Abraham, WM; Kraut, JA; Wu, D, 2013) |
| " The authors investigated the influence of hypovolemia on the effect of an inhalation anesthetic, isoflurane, in a swine hemorrhage model." | 7.73 | Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model. ( Fukuda, K; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2005) |
| " We investigated the changes in fibrinogen metabolism and coagulation after a moderate hemorrhage and resuscitation." | 7.73 | Effects of hemorrhage and lactated Ringer's resuscitation on coagulation and fibrinogen metabolism in swine. ( Chinkes, DL; Dubick, MA; Martini, WZ; Sondeen, J, 2006) |
| "Terlipressin (TP) is a vasopressin analogue used to reverse certain shock etiologies in some European countries." | 5.39 | Terlipressin with limited fluid resuscitation in a swine model of hemorrhage. ( Bielawski, A; DeVito, SS; Devlin, JJ; Gutierrez, MA; Henao, J; Johnson, AS; Kotora, J; Littlejohn, LF; Nowak, G, 2013) |
| " Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy." | 3.79 | The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013) |
| "These findings support the possible beneficial effects of sabiporide in the treatment of acute metabolic acidosis and could have implications for the treatment of metabolic acidosis in man." | 3.79 | Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. ( Abraham, WM; Kraut, JA; Wu, D, 2013) |
| " At a target pressure of 40 mmHg, the initial blood pressure response to oxygen is the same, but it gradually decreases as the animal develops a lactic acidosis." | 3.74 | Cardiovascular responses to oxygen inhalation after hemorrhage in anesthetized rats: hyperoxic vasoconstriction. ( Atkins, JL; Johnson, KB; Pearce, FJ, 2007) |
| " The authors investigated the influence of hypovolemia on the effect of an inhalation anesthetic, isoflurane, in a swine hemorrhage model." | 3.73 | Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model. ( Fukuda, K; Kurita, T; Morita, K; Sanjo, Y; Sato, S; Takata, K; Uraoka, M, 2005) |
| " We investigated the changes in fibrinogen metabolism and coagulation after a moderate hemorrhage and resuscitation." | 3.73 | Effects of hemorrhage and lactated Ringer's resuscitation on coagulation and fibrinogen metabolism in swine. ( Chinkes, DL; Dubick, MA; Martini, WZ; Sondeen, J, 2006) |
| "Among 111 non-massively bleeding trauma patients, 40 presented no indication for transfusion." | 2.87 | Blood Transfusion Indicators Following Trauma in the Non-Massively Bleeding Patient. ( Fontaine, MJ; Hu, PF; Kozar, RA; Li, HC; Mackenzie, CF; Miller, C; Parimi, N; Scalea, TM; Stein, DM; Yang, S, 2018) |
| "Of the 120 normotensive trauma patients, 30 (25 %) required at least one unit of packed red blood cells (RBC) and 12 (10 %) patients received at least four RBC within the first 48 h." | 2.82 | Capillary lactate concentration on admission of normotensive trauma patients: a prospective study. ( Bosson, JL; Bouzat, P; Brun, J; Manhes, P; Payen, JF; Schilte, C; Vinclair, M, 2016) |
| "Twelve pigs were subjected to hemorrhagic shock and 45 min of REBOA." | 1.91 | Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock. ( Ewer, N; Ford, R; Hoareau, GL; Johnson, MA; Neff, LP; Patel, N; Van Brocklin, MW; Vapniarsky, N; Williams, TK; Youngquist, ST, 2023) |
| "In hemodynamically normal trauma patients, the admission lactate of >4 mmol/L is a robust predictor of MT requirement and associated with poor outcomes." | 1.43 | Lactate predicts massive transfusion in hemodynamically normal patients. ( Brooke, M; Garcia, A; Miraflor, E; Victorino, GP; Yeung, L, 2016) |
| "Massive hemorrhage was defined as hemorrhage requiring transfusion of≥6 red cell concentrate units within 24h of admission." | 1.43 | Scoring system to predict hemorrhage in pelvic ring fracture. ( Hayashi, T; Inoue, T; Kitamura, T; Matsumoto, T; Numoto, K; Ohmori, T; Tada, K; Tamura, R; Tokioka, T, 2016) |
| "5 mM, 30- or 3-min incubation in blood or plasma) and after chronic use (50 mg/kg, i." | 1.42 | Cytidine 5'-diphosphocholine differentially affects hemostatic parameters in diverse conditions in rats: an investigation via thromboelastography. ( Cam, B; Sagdilek, E; Savci, V; Yildirim, N, 2015) |
| "Two cases with the diagnosis of Leigh syndrome was clear." | 1.42 | [Clinical characteristics and genetic analysis of two cases with Leigh syndrome with acute pulmonary hemorrhage as predominant manifestation]. ( Danqun, J; Jie, D; Kefei, H; Wenjia, T, 2015) |
| " However, the high molecular, positively charged PL is toxic in high doses, proposed as lysis of red blood cells." | 1.40 | In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats. ( Akerberg, D; Andersson, R; Isaksson, K; Posaric-Bauden, M; Tingstedt, B, 2014) |
| "Terlipressin (TP) is a vasopressin analogue used to reverse certain shock etiologies in some European countries." | 1.39 | Terlipressin with limited fluid resuscitation in a swine model of hemorrhage. ( Bielawski, A; DeVito, SS; Devlin, JJ; Gutierrez, MA; Henao, J; Johnson, AS; Kotora, J; Littlejohn, LF; Nowak, G, 2013) |
| "Patients undergoing elective abdominal aortic aneurysm surgery participated as control subjects." | 1.39 | Serum S100B protein is increased and correlates with interleukin 6, hypoperfusion indices, and outcome in patients admitted for surgical control of hemorrhage. ( Garini, E; Glynos, C; Kokkoris, S; Nanas, S; Pantziou, H; Psachoulia, C; Routsi, C; Stamataki, E; Stathopoulos, A, 2013) |
| "Hemorrhage was induced by withdrawing blood from the right femoral artery, and mean arterial pressure was maintained between 35 and 40 mm Hg for 30 min after which resuscitation was performed using normal saline (control), 3% hypertonic saline, or centhaquin dissolved in 3% hypertonic saline." | 1.38 | Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats. ( Garcia, DJ; Gulati, A; Havalad, S; Lavhale, MS, 2012) |
| "To study this, male rats underwent trauma-hemorrhage (mean blood pressure approximately 40 mmHg for 90 min) followed by fluid resuscitation." | 1.35 | Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1. ( Bland, KI; Chaudry, IH; Choudhry, MA; Hsieh, CH; Hsu, JT; Kan, WH; Schwacha, MG, 2008) |
| "Although arterial hypoxemia developed during the second run, arterial PO2 values were significantly (P < 0." | 1.31 | Effect of prior high-intensity exercise on exercise-induced arterial hypoxemia in Thoroughbred horses. ( Goetz, TE; Hassan, AS; Manohar, M, 2001) |
| "If glycogen is a limiting factor, as found with head-only stunning, pH drops too rapidly and affects water-holding capacity and color." | 1.31 | Effects of feed deprivation and electrical, gas, and captive needle stunning on early postmortem muscle metabolism and subsequent meat quality. ( Gerritzen, MA; Korf, J; Lambooij, E; Savenije, B; Schreurs, FJ; Winkelman-Goedhart, HA, 2002) |
| "Both steroids and hemorrhage may affect the hepatic energy metabolism." | 1.30 | [Effects of steroids on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage]. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1997) |
| "Glycogen in LR group was higher than that in the control group." | 1.30 | [Effects of lactated Ringer solution and acetated Ringer solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage]. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1998) |
| "Hemorrhage was initiated at t = 0 min or t = 70 min in groups I and II, respectively." | 1.28 | Systemic and mesenteric O2 metabolism in endotoxic pigs: effect of graded hemorrhage. ( Baum, TD; Fink, MP; Heard, SO; Rothschild, HR; Wang, HL, 1991) |
| "Pulmonary changes in acute cerebral ischemia were studied in anesthetized Mongolian gerbils, in which both carotid arteries were occluded simultaneously." | 1.27 | Pulmonary hemorrhage in experimental cerebral ischemia in mongolian gerbils. Brain metabolism and lung pathology. ( Fujishima, M; Ishitsuka, T; Nakatomi, Y; Ogata, J; Omae, T; Sadoshima, S; Tamaki, K, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (9.00) | 18.7374 |
| 1990's | 29 (29.00) | 18.2507 |
| 2000's | 23 (23.00) | 29.6817 |
| 2010's | 32 (32.00) | 24.3611 |
| 2020's | 7 (7.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, SJ | 3 |
| Zhou, ZW | 3 |
| Yang, C | 3 |
| Wei, KP | 3 |
| Ma, JZ | 3 |
| Chu, ZF | 3 |
| Gu, P | 3 |
| Griggs, JE | 2 |
| Lyon, RM | 2 |
| Sherriff, M | 2 |
| Barrett, JW | 2 |
| Wareham, G | 2 |
| Ter Avest, E | 2 |
| Wang, LL | 1 |
| Tian, YM | 1 |
| Hu, S | 1 |
| Zhang, HP | 2 |
| Meng, XX | 1 |
| Zhong, YX | 1 |
| Du, MH | 1 |
| Ding, Y | 1 |
| Talbot, CT | 1 |
| Zersen, KM | 1 |
| Hess, AM | 1 |
| Hall, KE | 1 |
| Patel, N | 1 |
| Johnson, MA | 2 |
| Vapniarsky, N | 1 |
| Van Brocklin, MW | 1 |
| Williams, TK | 2 |
| Youngquist, ST | 1 |
| Ford, R | 1 |
| Ewer, N | 1 |
| Neff, LP | 2 |
| Hoareau, GL | 2 |
| Liu, J | 1 |
| Cao, B | 1 |
| Luo, Y | 1 |
| Chen, X | 1 |
| Han, H | 1 |
| Li, L | 1 |
| Zeng, J | 1 |
| Fukuma, H | 1 |
| Nakada, TA | 1 |
| Shimada, T | 1 |
| Shimazui, T | 1 |
| Aizimu, T | 1 |
| Nakao, S | 1 |
| Watanabe, H | 1 |
| Mizushima, Y | 1 |
| Matsuoka, T | 1 |
| Gue, YX | 1 |
| Sayers, M | 1 |
| Whitby, BT | 1 |
| Kanji, R | 1 |
| Adatia, K | 1 |
| Smith, R | 1 |
| Davies, WR | 1 |
| Perperoglou, A | 1 |
| Potpara, TS | 1 |
| Lip, GYH | 1 |
| Gorog, DA | 1 |
| Schiller, AM | 1 |
| Howard, JT | 1 |
| Lye, KR | 1 |
| Magby, CG | 1 |
| Convertino, VA | 1 |
| Hamada, SR | 1 |
| Rosa, A | 1 |
| Gauss, T | 1 |
| Desclefs, JP | 1 |
| Raux, M | 1 |
| Harrois, A | 1 |
| Follin, A | 1 |
| Cook, F | 1 |
| Boutonnet, M | 2 |
| Attias, A | 1 |
| Ausset, S | 1 |
| Dhonneur, G | 1 |
| Duranteau, J | 2 |
| Langeron, O | 1 |
| Paugam-Burtz, C | 1 |
| Pirracchio, R | 1 |
| de St Maurice, G | 1 |
| Vigué, B | 1 |
| Rouquette, A | 1 |
| Parimi, N | 1 |
| Fontaine, MJ | 1 |
| Yang, S | 1 |
| Hu, PF | 1 |
| Li, HC | 1 |
| Mackenzie, CF | 1 |
| Kozar, RA | 1 |
| Miller, C | 1 |
| Scalea, TM | 2 |
| Stein, DM | 2 |
| Tibbits, EM | 1 |
| Simon, MA | 1 |
| Davidson, AJ | 1 |
| DeSoucy, ES | 1 |
| Faulconer, ER | 1 |
| Grayson, JK | 1 |
| Hoehn, MR | 1 |
| Teeter, WA | 1 |
| Morrison, JJ | 1 |
| Gamble, WB | 1 |
| Hu, P | 1 |
| Brenner, ML | 1 |
| Do, WS | 1 |
| Forte, DM | 1 |
| Sheldon, RR | 1 |
| Weiss, JB | 1 |
| Barron, MR | 1 |
| Sokol, KK | 1 |
| Black, GE | 1 |
| Hegge, SR | 1 |
| Eckert, MJ | 1 |
| Martin, MJ | 2 |
| Devlin, JJ | 1 |
| DeVito, SS | 1 |
| Littlejohn, LF | 1 |
| Gutierrez, MA | 1 |
| Nowak, G | 1 |
| Henao, J | 1 |
| Bielawski, A | 1 |
| Kotora, J | 1 |
| Johnson, AS | 1 |
| Stamataki, E | 1 |
| Stathopoulos, A | 1 |
| Garini, E | 1 |
| Kokkoris, S | 1 |
| Glynos, C | 1 |
| Psachoulia, C | 1 |
| Pantziou, H | 1 |
| Nanas, S | 1 |
| Routsi, C | 1 |
| Vanhuyse, F | 1 |
| Frotscher, B | 1 |
| Lecompte, T | 1 |
| Maureira, P | 1 |
| Villemot, JP | 1 |
| Folliguet, T | 1 |
| Toussaint-Hacquard, M | 1 |
| Pattarini, JM | 1 |
| Blue, RS | 1 |
| Aikins, LT | 1 |
| Law, J | 1 |
| Walshe, AD | 1 |
| Garbino, A | 1 |
| Turney, MW | 1 |
| Clark, JB | 1 |
| Lashof-Sullivan, M | 1 |
| Shoffstall, A | 1 |
| Lavik, E | 1 |
| Porta, CR | 1 |
| Nelson, D | 1 |
| McVay, D | 1 |
| Salgar, S | 1 |
| Eckert, M | 1 |
| Izenberg, S | 1 |
| Isaksson, K | 1 |
| Akerberg, D | 1 |
| Posaric-Bauden, M | 1 |
| Andersson, R | 1 |
| Tingstedt, B | 1 |
| Xia, J | 1 |
| Xie, N | 1 |
| Feng, Y | 1 |
| Yin, A | 1 |
| Liu, P | 1 |
| Zhou, R | 1 |
| Lin, F | 1 |
| Teng, G | 1 |
| Lei, Y | 1 |
| Hubbard, W | 1 |
| Keith, J | 1 |
| Berman, J | 1 |
| Miller, M | 1 |
| Scott, C | 1 |
| Peck, C | 1 |
| Chaudry, IH | 2 |
| Cam, B | 1 |
| Sagdilek, E | 1 |
| Yildirim, N | 1 |
| Savci, V | 1 |
| Soller, B | 1 |
| Zou, F | 1 |
| Prince, MD | 1 |
| Dubick, MA | 2 |
| Sondeen, JL | 1 |
| Lin, RL | 1 |
| Lin, YJ | 1 |
| Xu, F | 1 |
| Lee, LY | 1 |
| Vantrease, JE | 1 |
| Dudek, N | 1 |
| DonCarlos, LL | 1 |
| Scrogin, KE | 1 |
| Danqun, J | 1 |
| Jie, D | 1 |
| Wenjia, T | 1 |
| Kefei, H | 1 |
| Zhu, Y | 1 |
| Qiu, Y | 1 |
| Liao, L | 1 |
| Thanachartwet, V | 1 |
| Oer-Areemitr, N | 1 |
| Chamnanchanunt, S | 1 |
| Sahassananda, D | 1 |
| Jittmittraphap, A | 1 |
| Suwannakudt, P | 1 |
| Desakorn, V | 1 |
| Wattanathum, A | 1 |
| Bouzat, P | 1 |
| Schilte, C | 1 |
| Vinclair, M | 1 |
| Manhes, P | 1 |
| Brun, J | 1 |
| Bosson, JL | 1 |
| Payen, JF | 1 |
| Brooke, M | 1 |
| Yeung, L | 1 |
| Miraflor, E | 1 |
| Garcia, A | 1 |
| Victorino, GP | 1 |
| Ohmori, T | 1 |
| Matsumoto, T | 1 |
| Kitamura, T | 1 |
| Tamura, R | 1 |
| Tada, K | 1 |
| Inoue, T | 1 |
| Hayashi, T | 1 |
| Numoto, K | 1 |
| Tokioka, T | 1 |
| Justin, G | 1 |
| Finley, S | 1 |
| Abdur Rahman, AR | 1 |
| Guiseppi-Elie, A | 2 |
| Okamura, Y | 1 |
| Fukui, Y | 1 |
| Kabata, K | 1 |
| Suzuki, H | 1 |
| Handa, M | 1 |
| Ikeda, Y | 1 |
| Takeoka, S | 1 |
| Edwards, LN | 1 |
| Engle, TE | 1 |
| Correa, JA | 1 |
| Paradis, MA | 1 |
| Grandin, T | 1 |
| Anderson, DB | 1 |
| Scultetus, A | 1 |
| Arnaud, F | 1 |
| Kaplan, L | 1 |
| Shander, A | 1 |
| Philbin, N | 1 |
| Rice, J | 1 |
| McCarron, R | 1 |
| Freilich, D | 1 |
| Vandromme, MJ | 1 |
| Griffin, RL | 1 |
| McGwin, G | 1 |
| Weinberg, JA | 2 |
| Rue, LW | 1 |
| Kerby, JD | 1 |
| Gulati, A | 1 |
| Lavhale, MS | 1 |
| Garcia, DJ | 1 |
| Havalad, S | 1 |
| Wu, D | 1 |
| Kraut, JA | 1 |
| Abraham, WM | 1 |
| Friedman, Z | 1 |
| Berkenstadt, H | 1 |
| Preisman, S | 1 |
| Perel, A | 1 |
| Alam, HB | 1 |
| Uy, GB | 1 |
| Miller, D | 1 |
| Koustova, E | 1 |
| Hancock, T | 1 |
| Inocencio, R | 1 |
| Anderson, D | 1 |
| Llorente, O | 1 |
| Rhee, P | 1 |
| STEIN-WERBLOWSKY, R | 1 |
| VAN FOSSAN, DD | 2 |
| CLARK, RT | 2 |
| BIDDULPH, C | 1 |
| CRISCUOLO, D | 1 |
| Varela, JE | 1 |
| Cohn, SM | 1 |
| Diaz, I | 1 |
| Giannotti, GD | 1 |
| Proctor, KG | 2 |
| Kurita, T | 1 |
| Morita, K | 1 |
| Fukuda, K | 1 |
| Uraoka, M | 1 |
| Takata, K | 1 |
| Sanjo, Y | 1 |
| Sato, S | 1 |
| Satoh, K | 1 |
| Ohtawa, M | 1 |
| Katoh, M | 1 |
| Okamura, E | 1 |
| Satoh, T | 1 |
| Matsuura, A | 1 |
| Oi, Y | 1 |
| Ogawa, R | 1 |
| Silveira, SA | 1 |
| Haibara, AS | 1 |
| Coimbra, CC | 1 |
| Sinert, R | 2 |
| Tillotson, RD | 1 |
| Adar, E | 1 |
| Isaac, Y | 1 |
| Nagdev, A | 1 |
| Peng, J | 1 |
| Carrer, A | 1 |
| Shahidi, H | 1 |
| Zehtabchi, S | 2 |
| Goldman, M | 1 |
| Kapitanyan, R | 1 |
| Ballas, J | 1 |
| Zhou, D | 1 |
| Zu, Q | 1 |
| Martini, WZ | 1 |
| Chinkes, DL | 1 |
| Sondeen, J | 1 |
| Atkins, JL | 1 |
| Johnson, KB | 1 |
| Pearce, FJ | 1 |
| Meybohm, P | 1 |
| Cavus, E | 1 |
| Bein, B | 1 |
| Steinfath, M | 1 |
| Weber, B | 1 |
| Scholz, J | 1 |
| Doerges, V | 1 |
| Ditting, T | 1 |
| Hilgers, KF | 1 |
| Stetter, A | 1 |
| Linz, P | 1 |
| Schönweiss, C | 1 |
| Veelken, R | 1 |
| Hsu, JT | 1 |
| Kan, WH | 1 |
| Hsieh, CH | 1 |
| Choudhry, MA | 1 |
| Schwacha, MG | 1 |
| Bland, KI | 1 |
| Gustafsson, D | 1 |
| Andersson, LO | 1 |
| Lundvall, J | 1 |
| Ishitsuka, T | 1 |
| Fujishima, M | 1 |
| Sadoshima, S | 1 |
| Nakatomi, Y | 1 |
| Tamaki, K | 1 |
| Ogata, J | 1 |
| Omae, T | 1 |
| Kwan, E | 1 |
| Rurak, DW | 1 |
| Taylor, SM | 1 |
| McCoy, DE | 1 |
| Steele, JE | 1 |
| Cox, RH | 1 |
| Wiley, RL | 1 |
| Rocha e Silva, M | 1 |
| Braga, GA | 1 |
| Prist, R | 1 |
| Velasco, IT | 1 |
| Grança, ES | 1 |
| Van der Linden, P | 1 |
| Rausin, I | 1 |
| Deltell, A | 1 |
| Bekrar, Y | 1 |
| Gilbart, E | 1 |
| Bakker, J | 1 |
| Vincent, JL | 1 |
| Jeevaratnam, K | 1 |
| Sugendran, K | 1 |
| Vaidyanathan, CS | 1 |
| Pellicane, JV | 1 |
| Gore, DC | 1 |
| DeMaria, EJ | 1 |
| Delman, K | 1 |
| Malek, SK | 1 |
| Bundz, S | 1 |
| Abumrad, NN | 1 |
| Lang, CH | 1 |
| Molina, PE | 1 |
| Ikeya, K | 3 |
| Kashimoto, S | 4 |
| Kume, M | 3 |
| Kumazawa, T | 4 |
| Tamion, F | 1 |
| Richard, V | 1 |
| Lyoumi, S | 1 |
| Daveau, M | 1 |
| Bonmarchand, G | 1 |
| Leroy, J | 1 |
| Thuillez, C | 1 |
| Lebreton, JP | 1 |
| Winslow, RM | 2 |
| Gonzales, A | 1 |
| Gonzales, ML | 1 |
| Magde, M | 1 |
| McCarthy, M | 1 |
| Rohlfs, RJ | 1 |
| Vandegriff, KD | 1 |
| Schou, H | 1 |
| Kongstad, L | 1 |
| Perez de Sá, V | 1 |
| Werner, O | 1 |
| Larsson, A | 1 |
| Boiarinov, GA | 1 |
| Mukhina, IV | 1 |
| Penknovich, AA | 1 |
| Snopova, LB | 1 |
| Zimin, IuV | 1 |
| Balandina, MV | 1 |
| Radaev, AM | 1 |
| Skvortsova, IE | 1 |
| Prodanets, NN | 1 |
| Markos'ian, SA | 1 |
| Rasmussen, A | 1 |
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| Kristensen, M | 1 |
| Ott, P | 1 |
| Kirkegaard, P | 1 |
| Secher, NH | 1 |
| Alfaro, V | 1 |
| Pesquero, J | 1 |
| Palacios, L | 1 |
| Couëtil, LL | 1 |
| Denicola, DB | 1 |
| Manning, JE | 1 |
| Katz, LM | 1 |
| Brownstein, MR | 1 |
| Pearce, LB | 1 |
| Gawryl, MS | 1 |
| Baker, CC | 1 |
| Dowling, K | 1 |
| Herr, A | 1 |
| Siskin, G | 1 |
| Sansivero, GE | 1 |
| Stainken, B | 1 |
| Glass, TF | 1 |
| Fabian, MJ | 1 |
| Schweitzer, JB | 1 |
| Manohar, M | 2 |
| Goetz, TE | 2 |
| Hassan, AS | 2 |
| Baker, GJ | 1 |
| Xiao, G | 1 |
| Huang, N | 1 |
| Kheirabadi, BS | 1 |
| Tuthill, D | 1 |
| Pearson, R | 1 |
| Bayer, V | 1 |
| Beall, D | 1 |
| Drohan, W | 1 |
| MacPhee, MJ | 1 |
| Holcomb, JB | 1 |
| McNeil, CJ | 1 |
| Smith, LD | 1 |
| Jenkins, LD | 1 |
| York, MG | 1 |
| Josephs, MJ | 1 |
| Savenije, B | 1 |
| Schreurs, FJ | 1 |
| Winkelman-Goedhart, HA | 1 |
| Gerritzen, MA | 1 |
| Korf, J | 1 |
| Lambooij, E | 1 |
| Okuda, C | 1 |
| Sawa, T | 1 |
| Harada, M | 1 |
| Murakami, T | 1 |
| Matsuda, T | 1 |
| Tanaka, Y | 1 |
| Schlichtig, R | 2 |
| Klions, HA | 1 |
| Kramer, DJ | 2 |
| Nemoto, EM | 1 |
| Hannon, JP | 1 |
| Wade, CE | 2 |
| Bossone, CA | 1 |
| Hunt, MM | 1 |
| Coppes, RI | 1 |
| Loveday, JA | 1 |
| Heard, SO | 1 |
| Baum, TD | 1 |
| Wang, HL | 1 |
| Rothschild, HR | 1 |
| Fink, MP | 1 |
| Dunham, CM | 1 |
| Fabian, M | 1 |
| Siegel, JH | 1 |
| Gettings, L | 1 |
| Boston, JR | 1 |
| Pinsky, MR | 1 |
| Bickell, WH | 1 |
| Bruttig, SP | 1 |
| Millnamow, GA | 1 |
| O'Benar, J | 1 |
| Przybelski, RJ | 1 |
| Malcolm, DS | 1 |
| Burris, DG | 1 |
| Levin, GS | 1 |
| Shevchenko, LI | 1 |
| Gubaev, SA | 1 |
| Hinohara, S | 1 |
| Miyaji, T | 1 |
| Shchukina, MIa | 1 |
| Kernbach, G | 1 |
| Püschel, K | 1 |
| Brinkmann, B | 1 |
| Seyde, WC | 1 |
| McGowan, L | 1 |
| Lund, N | 1 |
| Duling, B | 1 |
| Longnecker, DE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "External Validation of the Clinical Pre-hospital Red- Flag Alert for Activation of Intra-hospital Hemorrhage Control Response in Blunt Trauma. A Prospective Multicentric Study"[NCT05820217] | 630 participants (Anticipated) | Observational | 2023-05-10 | Not yet recruiting | |||
| Evaluation of a Transfusion Therapy Using Whole Blood Versus Fractionated Blood Products in the Management of Coagulopathy in Patients Admitted to Hospital for Acute Traumatic Hemorrhage[NCT04431999] | Phase 3 | 200 participants (Anticipated) | Interventional | 2021-12-04 | Recruiting | ||
| Predictive Abilities for Transfusion Needs of Capillary Lactate Measure in Emergency for Injured Normotensive Patients[NCT01793428] | 120 participants (Actual) | Observational | 2011-08-31 | Completed | |||
| Establishment for Prediction Model of Intraoperative Blood Transfusion for Patients With Pelvic Fracture in China: A Multicenter Observational Study[NCT03855644] | 2,000 participants (Anticipated) | Observational [Patient Registry] | 2019-04-05 | Recruiting | |||
| A Prospective, Multi-Centric, Randomized, Double-Blind, Parallel, Phase-III Study to Assess Efficacy of PMZ-2010 as a Resuscitative Agent for Hypovolemic Shock to be Used as an Adjuvant to Standard Shock Treatment[NCT04045327] | Phase 3 | 105 participants (Actual) | Interventional | 2019-01-31 | Completed | ||
| A Prospective, Multi-centric, Randomized, Double-blind, Parallel, Saline Controlled Phase II Safety and Efficacy Study of PMZ-2010 as a Resuscitative Agent for Hypovolemic Shock to be Used Along With Standard Shock Treatment.[NCT04056065] | Phase 2 | 50 participants (Actual) | Interventional | 2017-05-29 | Completed | ||
| A Multicentric Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Centhaquine as an Adjuvant to the Standard of Care in COVID-19 Patients With Moderate to Severe Acute Respiratory Distress Syndrome[NCT05241067] | Phase 2 | 60 participants (Anticipated) | Interventional | 2024-03-31 | Not yet recruiting | ||
| A Prospective, Multi-centric, Open-labeled, Phase-IV Study to Assess Safety and Efficacy of LYFAQUIN™ (Centhaquine Citrate) as a Resuscitative Agent for Hypovolemic Shock to be Used as an Adjuvant to Standard Treatment of Shock[NCT05956418] | Phase 4 | 400 participants (Anticipated) | Interventional | 2021-08-13 | Recruiting | ||
| A Randomized, Double-blind, Placebo-controlled Phase I Study to Determine the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of PMZ-2010 (Centhaquin) in Healthy Male Volunteers[NCT02408731] | Phase 1 | 24 participants (Actual) | Interventional | 2014-10-31 | Completed | ||
| A Multi-Centric, Randomized, Double-Blind, Placebo-controlled, Phase-III Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent to be Used as an Adjuvant to Standard Treatment of Hypovolemic Shock[NCT05251181] | Phase 3 | 430 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| Use of Hypertonic Versus Isotonic Solutions in Off Pump Coronary Artery Bypass Graft Surgery Targeting the Left Marginal Branch[NCT01463917] | Phase 4 | 20 participants (Anticipated) | Interventional | 2011-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lactic acid and Hemorrhage
| Article | Year |
|---|---|
Risk factors of major bleeding detected by machine learning method in patients undergoing liver resection with controlled low central venous pressure technique.
Topics: Central Venous Pressure; Hemorrhage; Humans; Lactic Acid; Liver; Machine Learning; Risk Factors | 2023 |
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion; | 2013 |
Intravenous hemostats: challenges in translation to patients.
Topics: Animals; Antifibrinolytic Agents; Complement System Proteins; Erythrocytes; Fibrinogen; Hemorrhage; | 2013 |
4 trials available for lactic acid and Hemorrhage
93 other studies available for lactic acid and Hemorrhage
| Article | Year |
|---|---|
Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool.
Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Hospitals; Humans; Lactic Acid; Point-of- | 2022 |
Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool.
Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Hospitals; Humans; Lactic Acid; Point-of- | 2022 |
Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool.
Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Hospitals; Humans; Lactic Acid; Point-of- | 2022 |
Predictive clinical utility of pre-hospital point of care lactate for transfusion of blood product in patients with suspected traumatic haemorrhage: derivation of a decision-support tool.
Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Hospitals; Humans; Lactic Acid; Point-of- | 2022 |
Study on an Animal Model of Seawater Immersion Injury Following Hemorrhagic Shock.
Topics: Animals; Disease Models, Animal; Hemorrhage; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Resuscit | 2023 |
Shock index is positively correlated with acute blood loss and negatively correlated with cardiac output in a canine hemorrhagic shock model.
Topics: Anesthesia, General; Animals; Cardiac Output; Dog Diseases; Dogs; Hemorrhage; Lactic Acid; Shock, He | 2023 |
Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock.
Topics: Animals; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Hemorrhage; Lactic Acid | 2023 |
Prehospital lactate improves prediction of the need for immediate interventions for hemorrhage after trauma.
Topics: Adult; Area Under Curve; Blood Transfusion; Emergency Medical Services; Emergency Service, Hospital; | 2019 |
Usefulness of the NULL-PLEASE Score to Predict Survival in Out-of-Hospital Cardiac Arrest.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiopulmonary Resuscitation; Electric Countershock; Female; | 2020 |
Comparisons of Traditional Metabolic Markers and Compensatory Reserve as Early Predictors of Tolerance to Central Hypovolemia in Humans.
Topics: Adult; Blood Pressure; Female; Heart Rate; Hemodynamics; Hemorrhage; Humans; Hypovolemia; Lactic Aci | 2018 |
Development and validation of a pre-hospital "Red Flag" alert for activation of intra-hospital haemorrhage control response in blunt trauma.
Topics: Adult; Blood Transfusion; Chi-Square Distribution; Cohort Studies; Emergency Medical Services; Femal | 2018 |
Development and validation of a pre-hospital "Red Flag" alert for activation of intra-hospital haemorrhage control response in blunt trauma.
Topics: Adult; Blood Transfusion; Chi-Square Distribution; Cohort Studies; Emergency Medical Services; Femal | 2018 |
Development and validation of a pre-hospital "Red Flag" alert for activation of intra-hospital haemorrhage control response in blunt trauma.
Topics: Adult; Blood Transfusion; Chi-Square Distribution; Cohort Studies; Emergency Medical Services; Femal | 2018 |
Development and validation of a pre-hospital "Red Flag" alert for activation of intra-hospital haemorrhage control response in blunt trauma.
Topics: Adult; Blood Transfusion; Chi-Square Distribution; Cohort Studies; Emergency Medical Services; Femal | 2018 |
Endovascular variable aortic control (EVAC) versus resuscitative endovascular balloon occlusion of the aorta (REBOA) in a swine model of hemorrhage and ischemia reperfusion injury.
Topics: Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Endovascular Procedures; Female; Hemodyna | 2018 |
Aortic branch vessel flow during resuscitative endovascular balloon occlusion of the aorta.
Topics: Animals; Aorta; Arteries; Balloon Occlusion; Blood Flow Velocity; Disease Models, Animal; Endovascul | 2019 |
Minimally invasive preperitoneal balloon tamponade and abdominal aortic junctional tourniquet versus open packing for pelvic fracture-associated hemorrhage: Not all extrinsic compression is equal.
Topics: Animals; Aorta, Abdominal; Balloon Occlusion; Bandages; Blood Loss, Surgical; Fractures, Bone; Hemat | 2019 |
Terlipressin with limited fluid resuscitation in a swine model of hemorrhage.
Topics: Animals; Arterial Pressure; Disease Models, Animal; Fluid Therapy; Heart Rate; Hemorrhage; Lactic Ac | 2013 |
Serum S100B protein is increased and correlates with interleukin 6, hypoperfusion indices, and outcome in patients admitted for surgical control of hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Bicarbonates; Biomarkers; Female; Hemorr | 2013 |
[Use of rFVIIa in intractable hemorrhage in patients on central veno-arterial ECMO].
Topics: Adult; Blood Transfusion; Drug Resistance; Extracorporeal Membrane Oxygenation; Factor VIIa; Female; | 2013 |
The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis.
Topics: Acidosis; Animals; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; | 2013 |
In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats.
Topics: Animals; Edema; Hemorrhage; Injections, Intraperitoneal; Injections, Intravenous; Lactic Acid; Mater | 2014 |
Brain susceptibility weighted imaging signal changes in acute hemorrhagic anemia: an experimental study using a rabbit model.
Topics: Anemia; Animals; Bloodletting; Brain; Disease Models, Animal; Erythrocyte Count; Hematocrit; Hemoglo | 2014 |
17α-Ethynylestradiol-3-sulfate treatment of severe blood loss in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Et | 2015 |
Cytidine 5'-diphosphocholine differentially affects hemostatic parameters in diverse conditions in rats: an investigation via thromboelastography.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Collagen; Cytidine Diphosphate Choline; Hemoglobi | 2015 |
Comparison of Noninvasive pH and Blood Lactate as Predictors of Mortality in a Swine Hemorrhagic Shock with Restricted Volume Resuscitation Model.
Topics: Animals; Area Under Curve; Disease Models, Animal; Hemorrhage; Hydrogen-Ion Concentration; Lactic Ac | 2015 |
Hemorrhagic hypotension-induced hypersensitivity of vagal pulmonary C-fibers to chemical stimulation and lung inflation in anesthetized rats.
Topics: Action Potentials; Animals; Arterial Pressure; Chemoreceptor Cells; Disease Models, Animal; Hemorrha | 2015 |
5-HT1A receptors of the nucleus tractus solitarii facilitate sympathetic recovery following hypotensive hemorrhage in rats.
Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Disease Models, Animal; Hemorrhage; Hypotension; | 2015 |
[Clinical characteristics and genetic analysis of two cases with Leigh syndrome with acute pulmonary hemorrhage as predominant manifestation].
Topics: Brain; Carnitine; DNA, Mitochondrial; Female; Genetic Testing; Hemorrhage; Humans; Infant; Lactic Ac | 2015 |
Evaluation of Hemostatic Effects of Carbonized Hair-Loaded Poly(L-Lactic) Acid Nanofabrics.
Topics: Animals; Bandages; Carbon; Female; Femoral Artery; Hair; Hemorrhage; Hemostatics; Humans; Lactic Aci | 2015 |
Identification of clinical factors associated with severe dengue among Thai adults: a prospective study.
Topics: Adolescent; Adult; Age Factors; Child; Dengue Virus; Female; Hemorrhage; Humans; Lactic Acid; Logist | 2015 |
Lactate predicts massive transfusion in hemodynamically normal patients.
Topics: Adult; Biomarkers; Blood Transfusion; Female; Hemodynamics; Hemorrhage; Humans; Lactic Acid; Logisti | 2016 |
Scoring system to predict hemorrhage in pelvic ring fracture.
Topics: Abbreviated Injury Scale; Aged; Area Under Curve; Blood Transfusion; Case-Control Studies; Contrast | 2016 |
Biomimetic hydrogels for biosensor implant biocompatibility: electrochemical characterization using micro-disc electrode arrays (MDEAs).
Topics: Animals; Biomimetic Materials; Biosensing Techniques; Body Temperature; Glucose; Hemorrhage; Humans; | 2009 |
Novel platelet substitutes: disk-shaped biodegradable nanosheets and their enhanced effects on platelet aggregation.
Topics: Artificial Cells; Blood Platelets; Fibrinogen; Hemorrhage; Humans; Lactic Acid; Nanostructures; Olig | 2009 |
The relationship between exsanguination blood lactate concentration and carcass quality in slaughter pigs.
Topics: Abattoirs; Animals; Cadaver; Carbon Dioxide; Food Technology; Hemorrhage; Lactic Acid; Male; Meat; P | 2010 |
Hemoglobin-based oxygen carrier (HBOC-201) and escalating doses of recombinant factor VIIa (rFVIIa) as a novel pre-hospital resuscitation fluid in a swine model of severe uncontrolled hemorrhage.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Blood Substitutes; Disease Models, Animal; Dose-Respons | 2011 |
An implantable biochip to influence patient outcomes following trauma-induced hemorrhage.
Topics: Animals; Biosensing Techniques; Disease Models, Animal; Enzymes, Immobilized; Glucose; Glucose Oxida | 2011 |
Prospective identification of patients at risk for massive transfusion: an imprecise endeavor.
Topics: Adult; Blood Pressure; Blood Transfusion; Emergency Service, Hospital; Erythrocyte Transfusion; Hear | 2011 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
Topics: Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Cardiotonic Agents; Drug | 2012 |
Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs.
Topics: Acidosis; Animals; Cardiovascular System; Cation Transport Proteins; Familial Primary Pulmonary Hype | 2013 |
A comparison of lactated ringer's solution to hydroxyethyl starch 6% in a model of severe hemorrhagic shock and continuous bleeding in dogs.
Topics: Animals; Blood Loss, Surgical; Blood Pressure; Dogs; Hemodynamics; Hemorrhage; Hydroxyethyl Starch D | 2003 |
Comparative analysis of hemostatic agents in a swine model of lethal groin injury.
Topics: Animals; Bandages; Blood Pressure; Cardiac Output; Groin; Hemorrhage; Hemostatics; Lactic Acid; Mode | 2003 |
The early detection of cancer of the uterus.
Topics: Cervix Uteri; Climacteric; Early Detection of Cancer; Female; Hemorrhage; Humans; Lactic Acid; Menop | 1954 |
Postmortem diagnosis of hypoxia by means of brain lactic acid concentration.
Topics: Brain; Hemorrhage; Humans; Hypoxia; Lactic Acid | 1958 |
Relation of hypoxemia and/or hypocapnia to lactic acid content of brain and cardiovascular response.
Topics: Brain; Carbon Dioxide; Cardiovascular Physiological Phenomena; Cardiovascular System; Hemorrhage; Hu | 1958 |
Splanchnic perfusion during delayed, hypotensive, or aggressive fluid resuscitation from uncontrolled hemorrhage.
Topics: Acid-Base Equilibrium; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; | 2003 |
Influence of hypovolemia on the electroencephalographic effect of isoflurane in a swine model.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Electroencep | 2005 |
Pharmacological study of BRS, a new bicarbonated Ringer's solution, in haemorrhagic shock dogs.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Do | 2005 |
Hyperglycemic response to hemorrhage is modulated by baroreceptors unloading but not by peripheral chemoreceptors activation.
Topics: Animals; Blood Glucose; Blood Pressure; Carotid Body; Chemoreceptor Cells; Cyanides; Heart Rate; Hem | 2005 |
The effect of ethanol on uncontrolled hemorrhage in a rodent model.
Topics: Alcoholic Intoxication; Animals; Blood Pressure; Disease Models, Animal; Ethanol; Heart Rate; Hemorr | 2005 |
Diagnostic performance of serial haematocrit measurements in identifying major injury in adult trauma patients.
Topics: Adult; Female; Hematocrit; Hemorrhage; Humans; Infusions, Intravenous; Injury Severity Score; Lactic | 2006 |
[Effects of a hemostatic jelly with polylactic acid on hemostasis of injured cancellous bone].
Topics: Animals; Bone and Bones; Drug Combinations; Gelatin Sponge, Absorbable; Hemorrhage; Hemostatic Techn | 2006 |
Effects of hemorrhage and lactated Ringer's resuscitation on coagulation and fibrinogen metabolism in swine.
Topics: Animals; Blood Coagulation; Fibrinogen; Hematology; Hemorrhage; Isotonic Solutions; Lactic Acid; Res | 2006 |
Cardiovascular responses to oxygen inhalation after hemorrhage in anesthetized rats: hyperoxic vasoconstriction.
Topics: Acidosis, Lactic; Administration, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Cardiovascula | 2007 |
Neurochemical monitoring using intracerebral microdialysis during systemic haemorrhage.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabol | 2007 |
Renal sympathetic nerves modulate erythropoietin plasma levels after transient hemorrhage in rats.
Topics: Animals; Blood Pressure; Erythropoietin; Hemorrhage; Hypotension; Kidney; Kidney Diseases; Lactic Ac | 2007 |
Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1.
Topics: Animals; Chemokine CXCL1; Chemokine CXCL2; Estrogens; Heme Oxygenase-1; Hemorrhage; Intercellular Ad | 2008 |
Decrease in survival time in beta 2-adrenoceptor blocked cats exposed to bleeding.
Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Catecholamines; Cats; Glycerol; Hematocrit; Hem | 1984 |
Pulmonary hemorrhage in experimental cerebral ischemia in mongolian gerbils. Brain metabolism and lung pathology.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain; Brain Ischemia; Female; Gerbillinae; Hemorrh | 1984 |
Oxygen consumption, acid-base status, and behavior during and after acute, severe hemorrhage in fetal lambs.
Topics: Acid-Base Equilibrium; Acute Disease; Animals; Behavior, Animal; Blood Glucose; Blood Pressure; Elec | 1995 |
Swim training alters sympathoadrenal and endocrine responses to hemorrhage in borderline hypertensive rats.
Topics: Adrenal Glands; Animals; Blood Glucose; Blood Pressure; Catecholamines; Endocrine Glands; Heart Rate | 1995 |
Isochloremic hypertonic solutions for severe hemorrhage.
Topics: Acetates; Acetic Acid; Animals; Blood Gas Analysis; Blood Proteins; Blood Volume; Chlorides; Dextran | 1993 |
Detection of tissue hypoxia by arteriovenous gradient for PCO2 and pH in anesthetized dogs during progressive hemorrhage.
Topics: Animals; Carbon Dioxide; Dogs; Hemorrhage; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Aci | 1995 |
Do the hydrolysis products, methylamine and N,N'-dimethylurea, play any role in the methyl isocyanate-induced haematological and biochemical changes in rabbits?
Topics: Animals; Antisickling Agents; Cyanates; Erythrocyte Count; Female; Hemoglobins; Hemorrhage; Hydrolys | 1993 |
Decreased lactate in endotoxin-resistant mice undergoing hemorrhage is independent of tumor necrosis factor availability.
Topics: Animals; Blood Glucose; Drug Resistance; Endotoxins; Hematocrit; Hemorrhage; Lactates; Lactic Acid; | 1994 |
Resuscitation with lactated Ringer's solution after hemorrhage: lack of cardiac toxicity.
Topics: Animals; Blood Gas Analysis; Electrocardiography; Heart; Hemodynamics; Hemorrhage; Isotonic Solution | 1996 |
[Effects of steroids on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acidosis, Lactic; Acute Disease; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Glycogen | 1997 |
Gut ischemia and mesenteric synthesis of inflammatory cytokines after hemorrhagic or endotoxic shock.
Topics: Animals; Cytokines; Endotoxins; Hemodynamics; Hemorrhage; Inflammation Mediators; Interleukin-6; Int | 1997 |
[Effects of lactated Ringer solution and acetated Ringer solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Glycogen; Hemorrhage; Isotonic Solutions; Lactic Aci | 1998 |
Vascular resistance and the efficacy of red cell substitutes in a rat hemorrhage model.
Topics: Animals; Blood Pressure; Blood Substitutes; Blood Viscosity; Blood Volume; Exchange Transfusion, Who | 1998 |
Uncompensated blood loss is not tolerated during acute normovolemic hemodilution in anesthetized pigs.
Topics: Anesthesia; Animals; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Hematocrit; Hemod | 1998 |
[Mechanisms of actovegin effect on the central nervous system during postischemic period].
Topics: Animals; Brain; Carotid Arteries; Glucose; Heart Arrest; Heme; Hemodynamics; Hemorrhage; Injections, | 1998 |
[Effects of local ischemia on various parameters of the small intestine viability at different ages].
Topics: Age Factors; Animals; Catalase; Dogs; Hemorrhage; Intestine, Small; Ischemia; L-Lactate Dehydrogenas | 1998 |
[Effects of hypertonic lactated Ringer's solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Energy Metabolism; Glycogen; Hemorrhage; Hypertonic | 1998 |
Preserved arterial flow secures hepatic oxygenation during haemorrhage in the pig.
Topics: Animals; Blood Pressure; Catecholamines; Female; Heart Rate; Hemorrhage; Hepatic Artery; Lactic Acid | 1999 |
Acid-base disturbance during hemorrhage in rats: significant role of strong inorganic ions.
Topics: Acid-Base Equilibrium; Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Blo | 1999 |
Blood gas, plasma lactate and bronchoalveolar lavage cytology analyses in racehorses with respiratory disease.
Topics: Animals; Blood Gas Analysis; Bronchitis; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Exerc | 1999 |
Bovine hemoglobin-based oxygen carrier (HBOC-201) for resuscitation of uncontrolled, exsanguinating liver injury in swine. Carolina Resuscitation Research Group.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Blood Substitutes; Dose-Response Relationship, Drug; He | 2000 |
Use of a collagen plug device to seal a subclavian artery puncture secondary to intraarterial dialysis catheter placement.
Topics: Absorbable Implants; Aged; Biocompatible Materials; Catheterization, Peripheral; Catheters, Indwelli | 1999 |
The impact of hypercarbia on the evolution of brain injury in a porcine model of traumatic brain injury and systemic hemorrhage.
Topics: Animals; Axons; Blood Pressure; Brain; Brain Injuries; Brain Ischemia; Carbon Dioxide; Cardiac Outpu | 2001 |
Effect of prior high-intensity exercise on exercise-induced arterial hypoxemia in Thoroughbred horses.
Topics: Animals; Arteries; Bicarbonates; Blood Gas Analysis; Blood-Air Barrier; Body Temperature; Endoscopy; | 2001 |
Nasal strips do not affect pulmonary gas exchange, anaerobic metabolism, or EIPH in exercising Thoroughbreds.
Topics: Ammonia; Anaerobiosis; Animals; Blood Gas Analysis; Body Temperature; Endoscopy; Female; Heart Rate; | 2001 |
[Experimental study of the effect of dexamethasone on pulmonary diffuse hemorrhage and energy metabolism of mitochondria in the liver of guinea pig infected with leptospirosis].
Topics: Adenosine Triphosphatases; Animals; Anti-Inflammatory Agents; Dexamethasone; Energy Metabolism; Guin | 1999 |
Metabolic and hemodynamic effects of CO2 pneumoperitoneum in a controlled hemorrhage model.
Topics: Analysis of Variance; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Hemodynamics; | 2001 |
Effects of feed deprivation and electrical, gas, and captive needle stunning on early postmortem muscle metabolism and subsequent meat quality.
Topics: Abattoirs; Adenosine Triphosphate; Animals; Blood Glucose; Chickens; Electricity; Food Deprivation; | 2002 |
Lactate in rat skeletal muscle after hemorrhage measured by microdialysis probe calibrated in situ.
Topics: Acute Disease; Animals; Calibration; Dialysis; Extracellular Space; Hemorrhage; Lactates; Lactic Aci | 1992 |
Hepatic dysoxia commences during O2 supply dependence.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dogs; Hemorrhage; Hydroxybutyrates; Lactates; Lactic | 1992 |
Blood gas and acid-base status of conscious pigs subjected to fixed-volume hemorrhage and resuscitated with hypertonic saline dextran.
Topics: Acid-Base Imbalance; Animals; Bicarbonates; Blood; Carbon Dioxide; Dextrans; Hemorrhage; Hydrogen-Io | 1990 |
Systemic and mesenteric O2 metabolism in endotoxic pigs: effect of graded hemorrhage.
Topics: Animals; Escherichia coli; Hemorrhage; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Lipopolysa | 1991 |
Hepatic insufficiency and increased proteolysis, cardiac output, and oxygen consumption following hemorrhage.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Cardiac Output; Dogs; Endopeptidas | 1991 |
Renal O2 consumption during progressive hemorrhage.
Topics: Animals; Dogs; Hemorrhage; Kidney; Kinetics; Lactates; Lactic Acid; Oxygen Consumption; Renal Circul | 1991 |
The detrimental effects of intravenous crystalloid after aortotomy in swine.
Topics: Acid-Base Equilibrium; Animals; Aorta, Abdominal; Crystalloid Solutions; Female; Hemodynamics; Hemor | 1991 |
Cross-linked hemoglobin solution as a resuscitative fluid after hemorrhage in the rat.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Cross-Linking Reagents; Heart Rate; H | 1991 |
[Comparative evaluation of the effects of crystalloid solutions containing sodium lactate and sodium succinate on the hemodynamic indicators in different types of hemorrhage].
Topics: Animals; Crystalloid Solutions; Disease Models, Animal; Female; Hemodynamics; Hemorrhage; Isotonic S | 1991 |
Effects of naloxone on cardiac energy metabolism in acute hemorrhage in rats.
Topics: Animals; Energy Metabolism; Heart; Hemorrhage; Lactates; Lactic Acid; Male; Myocardium; Naloxone; Py | 1986 |
[Concentration of lactic acid in the blood and erythropoiesis during exposure to hypoxia].
Topics: Acclimatization; Altitude; Animals; Erythropoiesis; Hemoglobins; Hemorrhage; Hypoxia; Lactates; Lact | 1986 |
[Biochemical measurements of glucose metabolism in relation to cause of death and postmortem effects].
Topics: Acetone; Blood Glucose; Diabetes Mellitus; Diabetic Coma; Glycated Hemoglobin; Hemorrhage; Humans; L | 1986 |
Effects of anesthetics on regional hemodynamics in normovolemic and hemorrhaged rats.
Topics: Anesthesia, General; Anesthetics; Animals; Blood Pressure; Cardiac Output; Cerium Radioisotopes; Chl | 1985 |