Page last updated: 2024-10-17

lactic acid and Heart Valve Diseases

lactic acid has been researched along with Heart Valve Diseases in 14 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).

Research Excerpts

ExcerptRelevanceReference
"Pimobendan has gained enormous importance in the treatment of mitral valve disease in dogs."6.90Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly. ( Bach, JP; Iwanuk, N; Nolte, I; Pilgram, A; Raue, J; Rohn, K; Rumstedt, K; Sehn, M; Wall, L, 2019)
"We compared the onset of predictors for postoperative complications (lactate, total T2 (tT2), total T4 (tT4) and cortisone) retrospectively with the onset of altered growth hormone (GH) concentration in a patient who had had a lethal postoperative outcome and in 13 patients who were without postoperative complications for a period of 24 hours postoperatively."3.71Postoperative altered plasma growth hormone levels--a predictor for postoperative complications? A case report. ( Kirchner, E; Nietgen, G; Pirlich, M; Rümelin, A; Schäfers, HJ; Thum, P; von zur Mühlen, A, 2001)
"Pimobendan has gained enormous importance in the treatment of mitral valve disease in dogs."2.90Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly. ( Bach, JP; Iwanuk, N; Nolte, I; Pilgram, A; Raue, J; Rohn, K; Rumstedt, K; Sehn, M; Wall, L, 2019)
" Moreover, RAP lowered the volume of transfusion and dosage blood products."2.80Short-Term Effects and Safety Analysis of Retrograde Autologous Blood Priming for Cardiopulmonary Bypass in Patients with Cardiac Valve Replacement Surgery. ( Cheng, M; Li, JQ; Tian, WC; Wu, TC, 2015)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's2 (14.29)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwanuk, N1
Wall, L1
Nolte, I1
Raue, J1
Rumstedt, K1
Pilgram, A1
Sehn, M1
Rohn, K1
Bach, JP1
Song, Y1
Soh, S1
Shim, JK1
Park, KU1
Kwak, YL1
Soares, FB1
Pereira-Neto, GB1
Rabelo, RC1
Kamel, PI1
Qu, X1
Geiszler, AM1
Nagrath, D1
Harmancey, R1
Taegtmeyer, H1
Grande-Allen, KJ1
Cheng, M1
Li, JQ1
Wu, TC1
Tian, WC1
Trunk, P1
Gersak, B1
Salerno, TA1
Macedo, FI1
Ahlsson, A1
Sobrosa, C1
Kaijser, L1
Jansson, E1
Bomfim, V1
Jiang, Z1
Kejian, H1
Lei, CY1
Gu, K1
Rümelin, A1
Nietgen, G1
Pirlich, M1
Thum, P1
Schäfers, HJ1
von zur Mühlen, A1
Kirchner, E1
Wollert, HG1
Müller, W1
Fischer, D1
Wollert, U1
Schubert, F1
Krause, EG1
Panzner, R1
Smolenski, RT1
Swierczyński, J1
Narkiewicz, M1
Zydowo, MM1
Köhler, P1
Schwela, H1
Jecht, C1
Förster, D1
Klein, HH1
Spaar, U1
Schlepple, H1
Wiegand, V1
Kreuzer, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Adenosine on Myocardial Protection in Intermittent Warm Blood Cardioplegia: A Randomized Placebo-controlled Trial[NCT02681913]Phase 2100 participants (Anticipated)Interventional2016-02-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for lactic acid and Heart Valve Diseases

ArticleYear
Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Animals; Cardiomegaly; Dog Diseases; Dogs; Echocardiography; Exercise Test; Female; Heart Murmurs; H

2019
Short-Term Effects and Safety Analysis of Retrograde Autologous Blood Priming for Cardiopulmonary Bypass in Patients with Cardiac Valve Replacement Surgery.
    Cell biochemistry and biophysics, 2015, Volume: 73, Issue:2

    Topics: Adult; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Double-Blind Method; Female;

2015
Adenosine in cold blood cardioplegia--a placebo-controlled study.
    Interactive cardiovascular and thoracic surgery, 2012, Volume: 14, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Aged; Biopsy; Cold Temperature; Dose-Response Relationship, Drug; Do

2012
Effects of L-arginine cardioplegia on myocardium.
    The journal of extra-corporeal technology, 2001, Volume: 33, Issue:1

    Topics: Aged; Arginine; Cardiac Surgical Procedures; Cardioplegic Solutions; Female; Heart Arrest, Induced;

2001

Other Studies

10 other studies available for lactic acid and Heart Valve Diseases

ArticleYear
Skin perfusion pressure as an indicator of tissue perfusion in valvular heart surgery: Preliminary results from a prospective, observational study.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Acute Kidney Injury; Aged; Area Under Curve; Cardiopulmonary Bypass; Female; Heart Valve Diseases; H

2017
Assessment of plasma lactate and core-peripheral temperature gradient in association with stages of naturally occurring myxomatous mitral valve disease in dogs.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2018, Volume: 28, Issue:6

    Topics: Animals; Body Temperature; Dog Diseases; Dogs; Female; Heart Valve Diseases; Lactic Acid; Male; Mitr

2018
Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells.
    Journal of the Royal Society, Interface, 2014, Dec-06, Volume: 11, Issue:101

    Topics: Animals; Aortic Valve; Cell Survival; Collagen; Extracellular Matrix; Galactose; Glucose; Glutamic A

2014
Comparison of serum troponin I and plasma lactate concentrations in arrested versus beating-heart aortic valve replacement.
    The Journal of heart valve disease, 2010, Volume: 19, Issue:6

    Topics: Aged; Aorta; Aortic Valve; Biomarkers; Cardiopulmonary Bypass; Constriction; Coronary Circulation; C

2010
Beating-heart valve surgery: perspectives and insights into the future of myocardial protective strategies.
    The Journal of heart valve disease, 2010, Volume: 19, Issue:6

    Topics: Aorta; Aortic Valve; Biomarkers; Cardiopulmonary Bypass; Constriction; Coronary Circulation; Coronar

2010
Postoperative altered plasma growth hormone levels--a predictor for postoperative complications? A case report.
    Current medical research and opinion, 2001, Volume: 17, Issue:2

    Topics: Aged; Aortic Valve; Biomarkers; Cortisone; Heart Valve Diseases; Human Growth Hormone; Humans; Lacti

2001
[Heart surgery interventions in risk patients. New possibilities for improving therapeutic results].
    Zentralblatt fur Chirurgie, 1990, Volume: 115, Issue:14

    Topics: Adult; Cardiac Output; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Energy Metaboli

1990
Purines, lactate and phosphate release from child and adult heart during cardioplegic arrest.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Dec-03, Volume: 192, Issue:3

    Topics: Adult; Cardioplegic Solutions; Child; Child, Preschool; Coronary Disease; Heart Arrest, Induced; Hea

1990
[The behavior of ASAT, CK and LDH and lactate in patients with cardiac diseases in relation to graded ergometric stress with reference to assessing the performance capacity of patients].
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1989, Volume: 30, Issue:1

    Topics: Adult; Aspartate Aminotransferases; Creatine Kinase; Disability Evaluation; Exercise Test; Female; H

1989
Comparative analysis of myocardial enzyme activities of the energy-supplying metabolism in patients with dilative cardiomyopathies and valve diseases.
    Clinical cardiology, 1986, Volume: 9, Issue:5

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Cardiomyopathy, Dilated; Citric Acid Cycle; Creatine Kinase; Energ

1986