Page last updated: 2024-10-17

lactic acid and Heart Failure

lactic acid has been researched along with Heart Failure in 176 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Creatine supplementation in chronic heart failure augments skeletal muscle endurance and attenuates the abnormal skeletal muscle metabolic response to exercise."9.08The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure. ( Andrews, R; Cowley, AJ; Curtis, S; Greenhaff, P; Perry, A, 1998)
"Twelve outpatients with type II diabetes mellitus and mild clinical signs and history of cardiac failure were studied to assess the effects of ibopamine on glucose and lipid metabolism."9.06Safety of ibopamine in type II diabetic patients with mild chronic heart failure. A double-blind cross-over study. ( Cicchetti, V; DiCarlo, A; Giannarelli, R; Marchetti, P; Navalesi, R; Sabino, F, 1990)
"This study investigated the safe use of metformin in patients with (1) type 2 diabetes mellitus (T2DM) and heart failure on metformin, and (2) heart failure without T2DM and metformin naïve."8.31The safe use of metformin in heart failure patients both with and without T2DM: A cross-sectional and longitudinal study. ( Carland, JE; Chowdhury, G; Day, RO; Graham, G; Greenfield, JR; Hayward, CS; Kumar, S; Kumarasinghe, G; Macdonald, P; Olsen, N; Stocker, SL, 2023)
"The study aims to examine the predictive value of arterial blood lactic acid concentration for in-hospital all-cause mortality in the intensive care unit (ICU) for patients with acute heart failure (AHF)."8.12Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure. ( Chao, Y; Hu, W; Wang, X; Yan, X; Yuan, L; Zang, B; Zhang, Y; Zhao, W, 2022)
"The present study assesses whether ranolazine increases left ventricular (LV) function without an increase in myocardial oxygen consumption (MVO2) and thus improves LV mechanical efficiency in dogs with heart failure (HF)."7.71Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. ( Blackburn, B; Chandler, MP; Morita, H; Roth, BA; Sabbah, HN; Stanley, WC; Suzuki, G; Wolff, A, 2002)
"The effect of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine) on myocardial metabolism was investigated in an experimental model of ischemic acute heart failure (AHF) induced by coronary ligation in anesthetized dogs."7.70Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998)
"To evaluate purine degradation in patients with congestive heart failure concentrations of serum hypoxanthine, lactate, and noradrenaline were measured before and after submaximal treadmill exercise in 12 patients with chronic congestive heart failure and nine healthy volunteers."7.68Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure. ( Hisatome, I; Ishiko, R; Kinugawa, T; Kitamura, H; Kobayashi, M; Kotake, H; Mashiba, H; Miyakoda, H; Saito, M; Sato, R, 1990)
"The hemodynamic and myocardial metabolic effects of enoximone (phosphodiesterase III inhibitor), alone or in combination with metoprolol (beta-adrenergic blocker), were studied in patients with congestive heart failure."7.68Effect of enoximone alone and in combination with metoprolol on myocardial function and energetics in severe congestive heart failure: improvement in hemodynamic and metabolic profile. ( Branzi, A; Caldarera, I; Galie, N; Grattoni, C; Magnani, B; Magnani, G; Melandri, G; Rapezzi, C, 1993)
"The acute haemodynamic and myocardial metabolic effects of intravenous urapidil were evaluated in 12 patients with severe congestive heart failure due to coronary heart disease."7.67Acute haemodynamic and myocardial metabolic effects of intravenous urapidil in severe heart failure. ( Chan, KH; Chow, JS; Pan, HY; Wang, RY; Wong, RP, 1984)
"Thus, patients with severe chronic congestive heart failure display metabolic derangement in muscle, which, in this study, was not corrected by treatment with enalapril."6.67Muscle energy metabolism in severe chronic congestive heart failure--effect of treatment with enalapril. ( Broqvist, M; Dahlström, U; Karlsson, E; Larsson, J, 1992)
"Spontaneous hypercortisolism (HC) is a common endocrine disease of senior dogs, often overlapping in selected clinical signs and hematologic and blood biochemical abnormalities with nonadrenal diseases (NADs)."5.72Canine urinary lactate and cortisol metabolites in hypercortisolism, nonadrenal disease, congestive heart failure, and health. ( Burchell, RK; Fries, R; Gal, A; Kadotani, S; Li, Z; Lopez-Villalobos, N; Petreanu, Y; Scott-Moncrieff, JC; Ulanov, AV, 2022)
"Levosimendan was effective in improving heart function."5.51Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy. ( Bergounioux, J; Essid, A; Haegy, I; Josseran, L; Mbieleu, B; Sumanaru, D, 2019)
"The milrinone plasma level was significantly greater in group III than in the other groups (group I, 0 ng/mL; group II, 1."5.40Sustained release of milrinone delivered via microparticles in a rodent model of myocardial infarction. ( Al Kindi, H; Nepotchatykh, O; Paul, A; Prakash, S; Schwertani, A; Shum-Tim, D; You, Z, 2014)
"Ten patients with congestive heart failure (CHF) (NYHA II-IV) on adjusted doses of digitalis and diuretics underwent a careful clinical assessment including an evaluation of exertion dyspnoea and the usual echocardiographic indices of cardiac performance."5.27Sympathetic activation on effort in patients with chronic heart failure. Long term effects of captopril. ( Alunni, G; Boschetti, E; Bruni, B; Castellano, M; Cocchieri, M; Fortunati, F; Grassi, V; Tantucci, C, 1988)
"To clarify the intestinal barrier function (IBF) state of patients with acute myocardial infarction-heart failure (AMI-HF), and to compare the therapeutic effects of rhubarb and Pantoprazole (proton pump inhibitor)."5.16[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart]. ( Mao, XB; Mao, Y; Wang, SQ, 2012)
"Creatine supplementation in chronic heart failure augments skeletal muscle endurance and attenuates the abnormal skeletal muscle metabolic response to exercise."5.08The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure. ( Andrews, R; Cowley, AJ; Curtis, S; Greenhaff, P; Perry, A, 1998)
"Eight patients with mild heart failure were treated in random order for 1 week with 2 mg bumethanide at 0800 and 1200 (treatment 1) h, 1 mg bumethanide at 0800, 1200, 1800, 2200 (treatment 2) and 5 mg bendroflumethiazide at 0800 and 1800 (treatment 3) h."5.07A comparison of three diuretic regimens in heart failure. ( Andreasen, F; Bech, OM; Bruun, P; Diamant, B; Eriksen, UH; Guul, SJ; Hartling, OJ; Hvidt, S; Kahr, O; Nielsen, LP, 1993)
"The reduced maximal exercise capacity of patients with heart failure has been attributed to skeletal muscle underperfusion with resultant intramuscular lactic acidosis and muscular fatigue."5.06Effect of dichloroacetate on the exercise performance of patients with heart failure. ( Egler, J; Ferraro, N; Mancini, DM; Wilson, JR, 1988)
"Twelve outpatients with type II diabetes mellitus and mild clinical signs and history of cardiac failure were studied to assess the effects of ibopamine on glucose and lipid metabolism."5.06Safety of ibopamine in type II diabetic patients with mild chronic heart failure. A double-blind cross-over study. ( Cicchetti, V; DiCarlo, A; Giannarelli, R; Marchetti, P; Navalesi, R; Sabino, F, 1990)
"05) between two groups, which included birth weight (BW), weight on admission, gestational age, age on admission, mode of delivery, septic shock, heart failure, respiratory failure, pulmonary hypertension, hypothermia, serum lactic acid, and aspartate aminotransferase (AST)."4.31Risk factors for death caused by early onset sepsis in neonates: a retrospective cohort study. ( Chen, F; Chen, X; He, H; Hu, Y; Wei, H, 2023)
"This study investigated the safe use of metformin in patients with (1) type 2 diabetes mellitus (T2DM) and heart failure on metformin, and (2) heart failure without T2DM and metformin naïve."4.31The safe use of metformin in heart failure patients both with and without T2DM: A cross-sectional and longitudinal study. ( Carland, JE; Chowdhury, G; Day, RO; Graham, G; Greenfield, JR; Hayward, CS; Kumar, S; Kumarasinghe, G; Macdonald, P; Olsen, N; Stocker, SL, 2023)
", lactic acid, and 3-hydroxybutyric acid) levels have been suggested to reflect the dysbiosis of human gut microbiota, which represents an additional factor involved in the onset of heart failure (HF) disease."4.31HiSorb sorptive extraction for determining salivary short chain fatty acids and hydroxy acids in heart failure patients. ( Biagini, D; Di Francesco, F; Ghimenti, S; Lenzi, A; Lomonaco, T; Salvo, P; Vivaldi, FM, 2023)
"The study aims to examine the predictive value of arterial blood lactic acid concentration for in-hospital all-cause mortality in the intensive care unit (ICU) for patients with acute heart failure (AHF)."4.12Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure. ( Chao, Y; Hu, W; Wang, X; Yan, X; Yuan, L; Zang, B; Zhang, Y; Zhao, W, 2022)
"We evaluated the ability of four biomarkers (C-Reactive protein (CRP), lactate, mid-regional proadrenomedullin (MR-proADM) and procalcitonin (PCT)) to detect each kind of organ failure considered in the SOFA in 213 patients with infection, sepsis or septic shock, by using multivariate regression analysis and calculation of the area under the receiver operating curve (AUROC)."3.96MR- proADM to detect specific types of organ failure in infection. ( Aldecoa, C; Almansa, R; Andaluz-Ojeda, D; Andrés, C; Bermejo-Martin, JF; Calvo, D; Cicuendez, R; Esteban-Velasco, MC; Martín, S; Martin-Fernandez, M; Muñoz-Bellvís, L; Nogales, L; Ríos-Llorente, A; Sanchez-Barrado, E; Vaquero-Roncero, LM, 2020)
"The present study assesses whether ranolazine increases left ventricular (LV) function without an increase in myocardial oxygen consumption (MVO2) and thus improves LV mechanical efficiency in dogs with heart failure (HF)."3.71Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. ( Blackburn, B; Chandler, MP; Morita, H; Roth, BA; Sabbah, HN; Stanley, WC; Suzuki, G; Wolff, A, 2002)
"The effect of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine) on myocardial metabolism was investigated in an experimental model of ischemic acute heart failure (AHF) induced by coronary ligation in anesthetized dogs."3.70Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998)
"The purpose of this study was to examine the use of lactic acid levels and continuous central venous oxygen saturation (central venous oximetry) to stratify and treat patients with acutely decompensated end-stage chronic congestive heart failure (CHF) presenting to the emergency department."3.70Undetected cardiogenic shock in patients with congestive heart failure presenting to the emergency department. ( Ander, DS; Gryzbowski, M; Jaggi, M; Levine, AB; Levine, TB; Masura, J; Rady, MY; Rivers, E, 1998)
"64) l x min(-1)] and mean VO2 at lactic acidosis threshold [LAT, 0."3.70Gas exchange responses to continuous incremental cycle ergometry exercise in primary pulmonary hypertension in humans. ( Brundage, BH; Engelen, MP; Pórszász, J; Riley, MS; Wasserman, K, 2000)
"The hemodynamic and myocardial metabolic effects of enoximone (phosphodiesterase III inhibitor), alone or in combination with metoprolol (beta-adrenergic blocker), were studied in patients with congestive heart failure."3.68Effect of enoximone alone and in combination with metoprolol on myocardial function and energetics in severe congestive heart failure: improvement in hemodynamic and metabolic profile. ( Branzi, A; Caldarera, I; Galie, N; Grattoni, C; Magnani, B; Magnani, G; Melandri, G; Rapezzi, C, 1993)
" Twenty-five patients with chronic heart failure performed cycle ergometry for 6 min at 25 W and at a work rate midway (50 percent delta) between their lactic acidosis threshold (LAT) and peak VO2."3.68O2 uptake kinetics in response to exercise. A measure of tissue anaerobiosis in heart failure. ( Barstow, TJ; Ben-Dov, I; Mizumoto, G; Sietsema, KE; Sullivan, CS; Wasserman, K; Zhang, YY, 1993)
"To evaluate purine degradation in patients with congestive heart failure concentrations of serum hypoxanthine, lactate, and noradrenaline were measured before and after submaximal treadmill exercise in 12 patients with chronic congestive heart failure and nine healthy volunteers."3.68Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure. ( Hisatome, I; Ishiko, R; Kinugawa, T; Kitamura, H; Kobayashi, M; Kotake, H; Mashiba, H; Miyakoda, H; Saito, M; Sato, R, 1990)
"The acute haemodynamic and myocardial metabolic effects of intravenous urapidil were evaluated in 12 patients with severe congestive heart failure due to coronary heart disease."3.67Acute haemodynamic and myocardial metabolic effects of intravenous urapidil in severe heart failure. ( Chan, KH; Chow, JS; Pan, HY; Wang, RY; Wong, RP, 1984)
" To evaluate this relationship in chronic congestive heart failure (CHF), we studied eight patients with chronic CHF at baseline and during treatment with nitroglycerin."3.67Dependence of oxygen consumption on oxygen delivery in patients with chronic congestive heart failure. ( Amin, D; Jasper, AC; Koerner, SK; Mohsenifar, Z; Shah, PK, 1987)
"In order to determine the status of the energy production system of the heart during cardiac failure of sheep with gousiekte, observations were made of the heart tissue levels of adenosine triphosphate (ATP), creatine phosphate (CrP), inorganic phosphate, reduced nicotine adenine dinucleotide (NADH) and lactate."3.66A study on the function of some subcellular systems of the sheep myocardium during gousiekte. I. The energy production system. ( Pretorius, PJ; Snyman, LD; Van Der Walt, JJ, 1982)
"Thirty-three patients with congestive heart failure, New York Heart Association II or III symptoms, and left ventricular ejection fraction 25."2.71Effects of angiotensin-converting enzyme inhibitor plus irbesartan on maximal and submaximal exercise capacity and neurohumoral activation in patients with congestive heart failure. ( Blanchet, M; Curnier, D; De Champlain, J; Ducharme, A; Lamoureux, MC; Racine, N; Sheppard, R; Sirois, P; Tardif, JC; White, M, 2005)
"Thirty men (mean age 67+/-8 years) with congestive heart failure in NYHA class III (mean ejection fraction 32+/-5%) were evaluated prior to and following exercise training."2.70Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols. ( Aarsland, T; Dickstein, K; Haugland, A; Kristiansen, M; Larsen, AI, 2001)
"Twenty-seven patients with congestive heart failure [10 patients in functional class A (peak exercise O2 uptake >20 ml x kg-1 x min-1), 9 in class B (20-15 ml x kg-1 x min-1), and 8 in class C (15-10 ml x kg-1 x min-1)] underwent a cardiopulmonary exercise test with once-per-minute simultaneous blood sampling from the pulmonary and systemic arteries for determination of Hb, PO2, PCO2, pH, O2 content (CO2), Hb saturation and lactic acid (pulmonary artery only), and calculation of P50."2.68Contribution of PO2, P50, and Hb to changes in arteriovenous O2 content during exercise in heart failure. ( Agostoni, PG; Assanelli, E; Conconi, B; Guazzi, M; Lauri, G; Marenzi, GC; Palermo, P; Perego, GB; Sganzerla, P, 1996)
"Thus, patients with severe chronic congestive heart failure display metabolic derangement in muscle, which, in this study, was not corrected by treatment with enalapril."2.67Muscle energy metabolism in severe chronic congestive heart failure--effect of treatment with enalapril. ( Broqvist, M; Dahlström, U; Karlsson, E; Larsson, J, 1992)
"Cardiogenic shock has the potential for significant morbidity and mortality if not recognized early."2.66Identifying cardiogenic shock in the emergency department. ( Daly, M; Koyfman, A; Lentz, S; Long, B, 2020)
"Spontaneous hypercortisolism (HC) is a common endocrine disease of senior dogs, often overlapping in selected clinical signs and hematologic and blood biochemical abnormalities with nonadrenal diseases (NADs)."1.72Canine urinary lactate and cortisol metabolites in hypercortisolism, nonadrenal disease, congestive heart failure, and health. ( Burchell, RK; Fries, R; Gal, A; Kadotani, S; Li, Z; Lopez-Villalobos, N; Petreanu, Y; Scott-Moncrieff, JC; Ulanov, AV, 2022)
"BACKGROUND Hyperlactatemia is a common phenomenon following cardiac surgeries and is associated with prolonged ICU stay and higher morbidity and mortality rates, but such analyses have never focused on patients undergoing heart transplantation (HTX), in whom hyperlactatemia defined with the traditional threshold is observed in nearly every individual."1.56Postoperative Serum Lactate Levels for In-Hospital Mortality Prediction Among Heart Transplant Recipients. ( Drwiła, R; Górkiewicz-Kot, I; Hymczak, H; Kapelak, B; Kędziora, A; Milaniak, I; Piątek, J; Sobczyk, D; Tomsia, P; Wierzbicki, K, 2020)
"According to the new definition of septic shock, vasopressor therapy and hyperlactatemia are essential for diagnosis."1.51Risk factors for mortality in patients with low lactate level and septic shock. ( Choi, JY; Jeong, SJ; Jeong, WY; Jung, IY; Kim, EJ; Kim, JM; Kim, MH; Kim, YC; Ku, NS; Oh, DH; Song, JE; Song, YG, 2019)
"Levosimendan was effective in improving heart function."1.51Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy. ( Bergounioux, J; Essid, A; Haegy, I; Josseran, L; Mbieleu, B; Sumanaru, D, 2019)
"Cellular damage and cardiorespiratory failure are the most common causes of mortality and morbidity after poisoning."1.43Successful Treatment of Aluminium Phosphide Poisoning by Extracorporeal Membrane Oxygenation. ( Hajesmaeili, M; Hassanian-Moghaddam, H; Rahimi, M; Sadeghi, R; Taherkhani, M; Zamani, N, 2016)
"Lactic acid was injected into the arterial blood supply of the hind limb to stimulate ASIC3 in muscle afferent nerves and evoke muscle metaboreceptor response in control rats and HF rats."1.42ASIC3 contributes to the blunted muscle metaboreflex in heart failure. ( Li, J; Lu, J; Xing, J, 2015)
"High output cardiac failure is rare in MD patients and is related to myocardial abnormalities and hyperlactacidemia."1.40Refractory high output heart failure in a patient with primary mitochondrial respiratory chain disease. ( Horii, M; Kamon, D; Kawakami, R; Nakagawa, H; Nakano, T; Okayama, S; Onoue, K; Saito, Y; Sakaguchi, Y; Takemura, G; Uemura, S, 2014)
"The milrinone plasma level was significantly greater in group III than in the other groups (group I, 0 ng/mL; group II, 1."1.40Sustained release of milrinone delivered via microparticles in a rodent model of myocardial infarction. ( Al Kindi, H; Nepotchatykh, O; Paul, A; Prakash, S; Schwertani, A; Shum-Tim, D; You, Z, 2014)
"Cardiac functional deterioration in dilated cardiomyopathy (DCM) is known to be reversed by intramyocardial up-regulation of multiple cardioprotective factors, whereas a prostacyclin analog, ONO1301, has been shown to paracrinally activate interstitial cells to release a variety of protective factors."1.39A slow-releasing form of prostacyclin agonist (ONO1301SR) enhances endogenous secretion of multiple cardiotherapeutic cytokines and improves cardiac function in a rapid-pacing-induced model of canine heart failure. ( Daimon, T; Fukushima, S; Kawaguchi, N; Matsuura, N; Miyagawa, S; Nakatani, S; Okita, Y; Saito, A; Sakai, Y; Sawa, Y; Shiozaki, M; Shirasaka, T, 2013)
"Development of heart failure is known to be associated with changes in energy substrate metabolism."1.39Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. ( Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P, 2013)
"To evaluate the occurrence of arrhythmias and cardiovascular changes during 6WT."1.35Analysis of 6-minute walk test safety in pre-heart transplantation patients. ( Bernardelli, GF; Branco, JN; Buffolo, E; Cipriano, G; Mair, V; Yuri, D, 2009)
"and results Left ventricular hypertrophy was induced surgically in Sprague-Dawley rats by inter-renal aortic constriction."1.35Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy. ( Akki, A; Seymour, AM, 2009)
"Echocardiography demonstrated that right ventricular dysfunction occurred in the absence of recruitment."1.32Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. ( Ackerley, C; Duggan, M; Engelberts, D; Kavanagh, BP; McCaul, CL; McNamara, PJ, 2003)
"Congestive heart failure was produced by left coronary artery ligation in rats."1.31Beneficial effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor in rats with heart failure following myocardial infarction. ( Asaka, N; Hayashi, Y; Kirimoto, T; Matsuura, N; Miyake, H; Nakano, M; Tajima, K, 2000)
"Thus, cardiac failure was associated with decreased myocardial oxygen consumption and failure of oxygen consumption to increase with an increase in the level of exercise."1.30Regulation of myocardial blood flow by oxygen consumption is maintained in the failing heart during exercise. ( Bache, RJ; Crampton, M; Jones, B; Melchert, P; Pierpont, GL; Traverse, JH, 1999)
"4."1.29Ventilatory and heart rate responses after exercise in chronic cardiac failure. ( Nicholls, DP; Riley, M; Stanford, CF, 1994)
" The dosage of catecholamines was highest immediately after transplantation (2 h: 0."1.28[Hemodynamic characteristics of heart transplant patients in the early postoperative period]. ( Albes, J; Coppola, R; Cremer, J; Dammenhayn, L; Haverich, A; Schäfers, HJ; Wahlers, T, 1991)
" Moreover, the changes in peak skeletal muscle blood flow noted during long-term administration of captopril, an angiotensin-converting enzyme inhibitor, appears to correlate with the changes in aerobic capacity."1.27Direct and indirect assessment of skeletal muscle blood flow in chronic congestive heart failure. ( Katz, S; LeJemtel, TH; Scortichini, D, 1988)
"Ten patients with congestive heart failure (CHF) (NYHA II-IV) on adjusted doses of digitalis and diuretics underwent a careful clinical assessment including an evaluation of exertion dyspnoea and the usual echocardiographic indices of cardiac performance."1.27Sympathetic activation on effort in patients with chronic heart failure. Long term effects of captopril. ( Alunni, G; Boschetti, E; Bruni, B; Castellano, M; Cocchieri, M; Fortunati, F; Grassi, V; Tantucci, C, 1988)

Research

Studies (176)

TimeframeStudies, this research(%)All Research%
pre-199029 (16.48)18.7374
1990's40 (22.73)18.2507
2000's41 (23.30)29.6817
2010's43 (24.43)24.3611
2020's23 (13.07)2.80

Authors

AuthorsStudies
Marbach, JA1
Stone, S1
Schwartz, B1
Pahuja, M1
Thayer, KL1
Faugno, AJ1
Chweich, H1
Rabinowitz, JB1
Kapur, NK1
Gal, A1
Fries, R1
Kadotani, S1
Ulanov, AV1
Li, Z1
Scott-Moncrieff, JC1
Burchell, RK1
Lopez-Villalobos, N1
Petreanu, Y1
Lu, T1
Tan, L1
Xu, K1
Liu, J1
Liu, C1
Zhang, G1
Shi, R1
Huang, Z1
Hu, W2
Yuan, L2
Wang, X2
Zang, B2
Zhang, Y2
Yan, X2
Zhao, W2
Chao, Y2
Sundermeyer, J1
Dabboura, S1
Weimann, J1
Beer, BN1
Becher, PM1
Seiffert, M1
Kirchhof, P1
Blankenberg, S1
Westermann, D1
Schrage, B1
Chen, Y1
Yang, K1
Wu, B1
Lin, W1
Chen, S1
Xu, X2
Peng, C1
Xie, D1
Chowdhury, G1
Carland, JE1
Kumar, S1
Olsen, N1
Graham, G1
Kumarasinghe, G1
Hayward, CS1
Greenfield, JR1
Macdonald, P1
Day, RO1
Stocker, SL1
Chen, W1
Chen, M1
Qiao, X1
Lenzi, A1
Biagini, D1
Ghimenti, S1
Vivaldi, FM1
Salvo, P1
Di Francesco, F1
Lomonaco, T1
Guzelce, MC1
Colak, N1
Ucar, G1
Orhan, E1
Chen, X1
He, H1
Wei, H1
Chen, F1
Hu, Y1
Gizak, A1
McCubrey, JA1
Rakus, D1
Uyar, H1
Yesil, E1
Karadeniz, M1
Orscelik, O1
Ozkan, B1
Ozcan, T1
Cicek Yilmaz, D1
Celik, A1
Segreti, A1
Grigioni, F2
Campodonico, J1
Magini, A1
Zaffalon, D1
Sinagra, G2
Sciascio, GD1
Swenson, ER1
Agostoni, P3
Andrés, C1
Andaluz-Ojeda, D1
Cicuendez, R1
Nogales, L1
Martín, S1
Martin-Fernandez, M1
Almansa, R1
Calvo, D1
Esteban-Velasco, MC1
Vaquero-Roncero, LM1
Ríos-Llorente, A1
Sanchez-Barrado, E1
Muñoz-Bellvís, L1
Aldecoa, C1
Bermejo-Martin, JF1
Kędziora, A1
Wierzbicki, K1
Piątek, J1
Hymczak, H1
Górkiewicz-Kot, I1
Milaniak, I1
Tomsia, P1
Sobczyk, D1
Drwiła, R1
Kapelak, B1
Bhavani, SV1
Huang, ES1
Verhoef, PA1
Churpek, MM1
Daly, M1
Long, B1
Koyfman, A1
Lentz, S1
Bosso, G1
Mercurio, V1
Diab, N1
Pagano, A1
Porta, G1
Allegorico, E1
Serra, C1
Guiotto, G1
Numis, FG1
Tocchetti, CG1
Schiraldi, F1
Emdin, M1
De Martino, F1
Apostolo, A1
Masè, M1
Contini, M1
Carriere, C1
Vignati, C1
Cluntun, AA1
Badolia, R1
Lettlova, S1
Parnell, KM1
Shankar, TS1
Diakos, NA1
Olson, KA1
Taleb, I1
Tatum, SM1
Berg, JA1
Cunningham, CN1
Van Ry, T1
Bott, AJ1
Krokidi, AT1
Fogarty, S1
Skedros, S1
Swiatek, WI1
Yu, X1
Luo, B1
Merx, S1
Navankasattusas, S1
Cox, JE1
Ducker, GS1
Holland, WL1
McKellar, SH1
Rutter, J1
Drakos, SG1
Cetinkaya, HB1
Gunes, H1
Rossiter, HB1
Ørn, S1
van Hall, G1
Daniels, CE1
Litin, SC1
Bundrick, JB1
Kisaka, T1
Stringer, WW1
Koike, A1
Wasserman, K4
Oh, DH1
Kim, MH1
Jeong, WY1
Kim, YC1
Kim, EJ1
Song, JE1
Jung, IY1
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Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Exercise Conditioning in Elderly Patients With Heart Failure[NCT01113840]201 participants (Actual)Interventional1993-07-31Completed
Impaired Tissue Oxygen Delivery in Patients With Coexistent COPD-heart Failure: What Consequences on Neuromuscular Fatigue During Exercise?[NCT05235685]40 participants (Anticipated)Interventional2023-02-21Recruiting
Is Non-invasive Ventilation Effective in Improving the Exercise Capacity in Patients With Cardiac Heart Failure?: A Randomized Controlled Trial[NCT05433610]12 participants (Actual)Interventional2022-06-28Completed
The American Burn Association's Randomized Controlled Evaluation of Hemofiltration in Adult Burn Patients With Septic Shock and Acute Renal Failure[NCT01213914]37 participants (Actual)Interventional2011-08-31Active, not recruiting
Exercise Capacity, Muscle Strength, Respiratory Characteristics, Physical Activity and Quality of Life in Patients With Lung Cancer Awaiting Surgery[NCT04450719]47 participants (Actual)Observational2018-07-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for lactic acid and Heart Failure

ArticleYear
Lactate Clearance Is Associated With Improved Survival in Cardiogenic Shock: A Systematic Review and Meta-Analysis of Prognostic Factor Studies.
    Journal of cardiac failure, 2021, Volume: 27, Issue:10

    Topics: Heart Failure; Humans; Lactic Acid; Prognosis; Prospective Studies; Retrospective Studies; Shock, Ca

2021
Identifying cardiogenic shock in the emergency department.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Acidosis, Lactic; Bradycardia; Confusion; Early Diagnosis; Echocardiography; Edema; Electrocardiogra

2020
Roles of periodic breathing and isocapnic buffering period during exercise in heart failure.
    European journal of preventive cardiology, 2020, Volume: 27, Issue:2_suppl

    Topics: Anaerobic Threshold; Bicarbonates; Buffers; Cardiorespiratory Fitness; Exercise Test; Exercise Toler

2020
Mechanisms That Modulate Peripheral Oxygen Delivery during Exercise in Heart Failure.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:Supplement

    Topics: Blood Gas Analysis; Cardiac Output; Exercise Tolerance; Heart Failure; Humans; Lactic Acid; Oxygen;

2017
[From rest to run--make your heart failure patients exercise for a long life].
    MMW Fortschritte der Medizin, 2013, Mar-07, Volume: 155, Issue:4

    Topics: Contraindications; Exercise; Exercise Therapy; Heart Failure; Heart Rate; Humans; Lactic Acid; Oxyge

2013
Essential amino acids and exercise tolerance in elderly muscle-depleted subjects with chronic diseases: a rehabilitation without rehabilitation?
    BioMed research international, 2014, Volume: 2014

    Topics: Aged; Aged, 80 and over; Chronic Disease; Exercise Therapy; Exercise Tolerance; Female; Heart Failur

2014
[Physiopathology of exercise. Muscular adaptations].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:3

    Topics: Adaptation, Physiological; Anaerobic Threshold; Biopsy; Exercise; Exercise Test; Exercise Tolerance;

2000
[Threshold parameters in clinical practice].
    Orvosi hetilap, 2000, Oct-29, Volume: 141, Issue:44

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Lactic; Anaerobic Threshold; Diagnosis, Differ

2000
[Lactate in cardiac rehabilitation].
    Herz, 2001, Volume: 26, Issue:7

    Topics: Adult; Age Factors; Aged; Anaerobic Threshold; Coronary Disease; Exercise; Heart Failure; Humans; La

2001
Concepts and applications of cardiopulmonary exercise testing.
    Chest, 1988, Volume: 93, Issue:4

    Topics: Dyspnea; Exercise Test; Heart Failure; Humans; Lactates; Lactic Acid; Physical Exertion; Pulmonary G

1988

Trials

21 trials available for lactic acid and Heart Failure

ArticleYear
Effect of ventilatory support on functional capacity in patients with heart failure: a pilot study.
    Arquivos brasileiros de cardiologia, 2011, Volume: 96, Issue:3

    Topics: Adult; Blood Pressure; Dyspnea; Exercise Test; Female; Heart Failure; Humans; Lactic Acid; Male; Mid

2011
[Effects of added therapy with Chinese herbal medicine Kanli Granule on skeletal muscle dysfunction in patients with chronic heart failure].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:3

    Topics: Aged; Chronic Disease; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Lactic Acid; Male; Midd

2012
The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy.
    European journal of preventive cardiology, 2014, Volume: 21, Issue:2

    Topics: Adult; Ammonia; Biomarkers; Brazil; Cardiovascular Agents; Cross-Over Studies; Heart Failure; Humans

2014
[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2012, Volume: 32, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Endotoxins; Female; Glutamine; Heart Failure; Humans;

2012
Skeletal muscle reflex in heart failure patients: role of hydrogen.
    Circulation, 2003, Jan-21, Volume: 107, Issue:2

    Topics: Aged; Chemoreceptor Cells; Dopamine; Exercise Test; Female; Food, Formulated; Hand Strength; Heart F

2003
Effects of angiotensin-converting enzyme inhibitor plus irbesartan on maximal and submaximal exercise capacity and neurohumoral activation in patients with congestive heart failure.
    American heart journal, 2005, Volume: 149, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Comp

2005
An alternative approach for exercise prescription and efficacy testing in patients with chronic heart failure: a randomized controlled training study.
    American heart journal, 2005, Volume: 149, Issue:5

    Topics: Aged; Anaerobic Threshold; Catecholamines; Echocardiography; Exercise Test; Exercise Therapy; Exerci

2005
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To

2008
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To

2008
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To

2008
Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Adult; Blood Volume; Cardiac Output; Cardiography, Impedance; Chronic Disease; Exercise; Exercise To

2008
Can anaerobic threshold be used as an end-point for therapeutic trials in heart failure? Lessons from a multicentre randomized placebo-controlled trial. The VO2 French Study Group.
    European heart journal, 1994, Volume: 15, Issue:2

    Topics: Anaerobic Threshold; Angiotensin-Converting Enzyme Inhibitors; Double-Blind Method; Exercise Test; H

1994
A comparison of three diuretic regimens in heart failure.
    European journal of clinical investigation, 1993, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Blood Volume; Bumetanide; Circadian Rhythm; Diuretics;

1993
Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure.
    The American journal of cardiology, 1996, Nov-01, Volume: 78, Issue:9

    Topics: Chronic Disease; Dyspnea; Exercise; Fatigue; Female; Heart Failure; Heart Rate; Hemodynamics; Humans

1996
Contribution of PO2, P50, and Hb to changes in arteriovenous O2 content during exercise in heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 80, Issue:2

    Topics: Anaerobic Threshold; Blood Gas Analysis; Carbon Dioxide; Carboxyhemoglobin; Exercise; Exercise Test;

1996
The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure.
    European heart journal, 1998, Volume: 19, Issue:4

    Topics: Aged; Ammonia; Cardiotonic Agents; Creatine; Dietary Supplements; Exercise Test; Exercise Tolerance;

1998
Altered purine and glycogen metabolism in skeletal muscle during exercise in patients with heart failure.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:4

    Topics: Ammonia; Blood Pressure; Exercise; Exercise Test; Female; Glycogen; Heart Failure; Heart Rate; Human

1999
Lack of effect of increased inspired oxygen concentrations on maximal exercise capacity or ventilation in stable heart failure.
    The American journal of cardiology, 1999, Dec-15, Volume: 84, Issue:12

    Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Electrocardiography; Exercise Test; Female; He

1999
Assessing the effect of exercise training in men with heart failure; comparison of maximal, submaximal and endurance exercise protocols.
    European heart journal, 2001, Volume: 22, Issue:8

    Topics: Aged; Blood Gas Analysis; Clinical Protocols; Exercise Test; Exercise Therapy; Exercise Tolerance; H

2001
[Physical training as interval or continuous training in chronic heart failure for improving functional capacity, hemodynamics and quality of life--a controlled study].
    Zeitschrift fur Kardiologie, 2002, Volume: 91, Issue:4

    Topics: Activities of Daily Living; Cardiac Output; Chronic Disease; Exercise Test; Female; Follow-Up Studie

2002
Muscle energy metabolism in severe chronic congestive heart failure--effect of treatment with enalapril.
    European heart journal, 1992, Volume: 13, Issue:9

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Biopsy; Double-Blind Method; Drug Therapy, Combinat

1992
Safety of ibopamine in type II diabetic patients with mild chronic heart failure. A double-blind cross-over study.
    Cardiology, 1990, Volume: 77 Suppl 5

    Topics: Aged; C-Peptide; Cardiotonic Agents; Deoxyepinephrine; Diabetes Mellitus, Type 2; Double-Blind Metho

1990
Effect of dichloroacetate on the exercise performance of patients with heart failure.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:6

    Topics: Acetates; Acidosis, Lactic; Adult; Aged; Dichloroacetic Acid; Exercise; Fatigue; Heart Failure; Huma

1988
[Chronic therapy of congestive cardiomyopathy: effects of prenalterol and digoxin].
    Zeitschrift fur Kardiologie, 1985, Volume: 74, Issue:7

    Topics: Adult; Cardiac Output; Cardiac Volume; Cardiomyopathy, Dilated; Cardiotonic Agents; Clinical Trials

1985

Other Studies

145 other studies available for lactic acid and Heart Failure

ArticleYear
Canine urinary lactate and cortisol metabolites in hypercortisolism, nonadrenal disease, congestive heart failure, and health.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2022, Volume: 34, Issue:4

    Topics: Animals; Creatinine; Cushing Syndrome; Dog Diseases; Dogs; Heart Failure; Hydrocortisone; Lactic Aci

2022
Outcomes of hyperlactatemia on admission in critically ill patients with acute myocardial infarction: A retrospective study from MIMIC-IV.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Critical Illness; Heart Failure; Humans; Hyperlactatemia; Lactic Acid; Myocardial Infarction; Retros

2022
Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure.
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Heart Failure; Hospitals; Humans; Lactic Acid; Retrospective Studies

2022
Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure.
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Heart Failure; Hospitals; Humans; Lactic Acid; Retrospective Studies

2022
Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure.
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Heart Failure; Hospitals; Humans; Lactic Acid; Retrospective Studies

2022
Predictive Value of Arterial Blood Lactic Acid Concentration on the Risk of in-Hospital All-Cause Death in Patients with Acute Heart Failure.
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Heart Failure; Hospitals; Humans; Lactic Acid; Retrospective Studies

2022
Short-Term Lactate Kinetics in Patients With Cardiogenic Shock.
    JACC. Heart failure, 2023, Volume: 11, Issue:4

    Topics: Heart Failure; Heart-Assist Devices; Humans; Kinetics; Lactic Acid; Shock, Cardiogenic

2023
Association between lactate/albumin ratio and mortality in patients with heart failure after myocardial infarction.
    ESC heart failure, 2023, Volume: 10, Issue:3

    Topics: Albumins; Heart Failure; Humans; Lactic Acid; Myocardial Infarction; Retrospective Studies

2023
The safe use of metformin in heart failure patients both with and without T2DM: A cross-sectional and longitudinal study.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:8

    Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypoglycemic Agents; Lact

2023
Interaction of lactate/albumin and geriatric nutritional risk index on the all-cause mortality of elderly patients with critically ill heart failure: A cohort study.
    Clinical cardiology, 2023, Volume: 46, Issue:7

    Topics: Aged; Cohort Studies; Critical Illness; Geriatric Assessment; Heart Failure; Humans; Lactic Acid; Nu

2023
HiSorb sorptive extraction for determining salivary short chain fatty acids and hydroxy acids in heart failure patients.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023, Aug-01, Volume: 1228

    Topics: Acetic Acid; Butyric Acid; Dysbiosis; Fatty Acids; Fatty Acids, Volatile; Gas Chromatography-Mass Sp

2023
Prognostic value of the NEWS + Lactate score in patients with decompensated heart failure in the emergency department.
    ESC heart failure, 2023, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Early Warning Score; Emergency Service, Hospital;

2023
Risk factors for death caused by early onset sepsis in neonates: a retrospective cohort study.
    BMC infectious diseases, 2023, Nov-30, Volume: 23, Issue:1

    Topics: Birth Weight; Heart Failure; Humans; Infant; Infant, Newborn; Lactic Acid; Prognosis; Retrospective

2023
Cell-to-cell lactate shuttle operates in heart and is important in age-related heart failure.
    Aging, 2020, 02-08, Volume: 12, Issue:4

    Topics: Aging; Animals; Cell Cycle; Cell Line; Fibroblasts; Heart Failure; Lactic Acid; Mice; Myocardium; My

2020
The Effect of High Lactate Level on Mortality in Acute Heart Failure Patients With Reduced Ejection Fraction Without Cardiogenic Shock.
    Cardiovascular toxicology, 2020, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Female; Heart Failure; Humans; Lactic Acid; Male; Middle Aged;

2020
Chemoreceptor hyperactivity in heart failure: Is lactate the culprit?
    European journal of preventive cardiology, 2021, 08-09, Volume: 28, Issue:9

    Topics: Chemoreceptor Cells; Heart Failure; Humans; Lactic Acid

2021
MR- proADM to detect specific types of organ failure in infection.
    European journal of clinical investigation, 2020, Volume: 50, Issue:6

    Topics: Adrenomedullin; Aged; Aged, 80 and over; Area Under Curve; Blood Coagulation Disorders; C-Reactive P

2020
Postoperative Serum Lactate Levels for In-Hospital Mortality Prediction Among Heart Transplant Recipients.
    Annals of transplantation, 2020, May-26, Volume: 25

    Topics: Adult; Critical Care; Female; Heart Failure; Heart Transplantation; Hospital Mortality; Humans; Hype

2020
Novel Temperature Trajectory Subphenotypes in COVID-19.
    Chest, 2020, Volume: 158, Issue:6

    Topics: Adult; Age Factors; Aged; Antipyretics; Bilirubin; Black or African American; Body Mass Index; Body

2020
Time-weighted lactate as a predictor of adverse outcome in acute heart failure.
    ESC heart failure, 2021, Volume: 8, Issue:1

    Topics: Heart Failure; Hospitalization; Humans; Intensive Care Units; Italy; Lactic Acid

2021
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
    Cell metabolism, 2021, 03-02, Volume: 33, Issue:3

    Topics: Animals; Anion Transport Proteins; Cardiomegaly; Heart Failure; Heart-Assist Devices; Humans; Lactic

2021
Use of Shock Index and Lactate to Predict Mortality in Acute Heart Failure Patients in Emergency Department.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:3

    Topics: Emergency Service, Hospital; Heart Failure; Hospital Mortality; Humans; Lactic Acid; Prognosis; Retr

2021
The "Anaerobic Threshold" Concept Is Valid in Physiology and Medicine.
    Medicine and science in sports and exercise, 2021, 05-01, Volume: 53, Issue:5

    Topics: Anaerobic Threshold; Carbon Dioxide; Exercise; Heart Failure; Humans; Lactic Acid; Oxygen; Pulmonary

2021
Does a normal peripheral lactate value always indicate an aerobic tissue metabolism?
    European journal of heart failure, 2017, Volume: 19, Issue:8

    Topics: Heart Failure; Humans; Lactic Acid; Oxygen Consumption; Reference Values

2017
Clinical pearls in pulmonary diseases.
    Disease-a-month : DM, 2017, Volume: 63, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Asthma; Confusion; Cough; Female; Heart

2017
Risk factors for mortality in patients with low lactate level and septic shock.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2019, Volume: 52, Issue:3

    Topics: Aged; APACHE; C-Reactive Protein; Chronic Disease; Cohort Studies; Female; Heart Failure; Humans; Hy

2019
Blood lactate is a predictor of short-term mortality in patients with myocardial infarction complicated by heart failure but without cardiogenic shock.
    BMC cardiovascular disorders, 2018, 01-18, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Coronary Angiography; Female; Heart Failure; Humans; Kap

2018
Increased blood lactate is prevalent and identifies poor prognosis in patients with acute heart failure without overt peripheral hypoperfusion.
    European journal of heart failure, 2018, Volume: 20, Issue:6

    Topics: Acute Disease; Aged; Biomarkers; Disease Progression; Female; Heart Failure; Humans; Lactic Acid; Ma

2018
Risk factors and outcomes of sepsis-induced myocardial dysfunction and stress-induced cardiomyopathy in sepsis or septic shock: A comparative retrospective study.
    Medicine, 2018, Volume: 97, Issue:13

    Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Cytokines; Diabetes Mellitus; Echocar

2018
I will take my heart failure 'lactate-free' please.
    European journal of heart failure, 2018, Volume: 20, Issue:6

    Topics: Heart Failure; Humans; Lactic Acid; Prevalence; Prognosis

2018
Prognostic Value of Serum Lactate Levels in Patients Undergoing Urgent Heart Transplant: A Subanalysis of the ASIS-TC Spanish Multicenter Study.
    Revista espanola de cardiologia (English ed.), 2019, Volume: 72, Issue:3

    Topics: Biomarkers; Emergencies; Female; Follow-Up Studies; Heart Failure; Heart Transplantation; Humans; La

2019
Risk factors associated with 30-day mortality for out-of-center ECMO support: experience from the newly launched ECMO retrieval service.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2019, Volume: 22, Issue:2

    Topics: Adult; Aged; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Female; Germany; He

2019
Levosimendan as Rescue Therapy for Acute Heart Failure in a Patient with Duchenne Muscular Dystrophy.
    Pediatric cardiology, 2019, Volume: 40, Issue:3

    Topics: Acute Disease; Adult; Cardiomyopathies; Cardiotonic Agents; Heart Failure; Humans; Lactic Acid; Male

2019
Sex Differences in Heart Failure With Preserved Ejection Fraction Pathophysiology: A Detailed Invasive Hemodynamic and Echocardiographic Analysis.
    JACC. Heart failure, 2019, Volume: 7, Issue:3

    Topics: Aged; Blood Flow Velocity; Blood Gas Analysis; Compliance; Diffusion; Echocardiography; Exercise Tes

2019
New-Onset Heart Failure.
    JAMA cardiology, 2019, 06-01, Volume: 4, Issue:6

    Topics: Acidosis; Adult; Alcoholism; Beriberi; Dyspnea; Echocardiography; Edema; Electrocardiography; Heart

2019
Acute heart failure, iron deficiency, and hyperlactataemia: a high-risk combination.
    Kardiologia polska, 2019, Volume: 77, Issue:3

    Topics: Anemia, Iron-Deficiency; Heart Failure; Humans; Lactic Acid

2019
Cavo-pulmonary anastomosis associated with left ventricular in comparison with biventricular circulatory support in acute heart failure.
    Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular, 2012, Volume: 27, Issue:4

    Topics: Animals; Cytokines; Disease Models, Animal; Heart Bypass, Right; Heart Failure; Heart Ventricles; He

2012
A slow-releasing form of prostacyclin agonist (ONO1301SR) enhances endogenous secretion of multiple cardiotherapeutic cytokines and improves cardiac function in a rapid-pacing-induced model of canine heart failure.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:2

    Topics: Animals; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Cardiovascula

2013
Left ventricular assist device effects on metabolic substrates in the failing heart.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Alanine; Amino Acids, Aromatic; Case-Control Studies; Creatine; Female; Glucose; Glutamine; H

2013
Metabonomics analysis of plasma reveals the lactate to cholesterol ratio as an independent prognostic factor of short-term mortality in acute heart failure.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Acute Disease; Aged; Aged, 80 and over; Area Under Curve; Cholesterol; Cohort Studies; Female; Heart

2013
Increased catabolic activity in adipose tissue of patients with chronic heart failure.
    European journal of heart failure, 2013, Volume: 15, Issue:10

    Topics: Adipose Tissue; Adult; Aged; Atrial Natriuretic Factor; Blood Glucose; Cachexia; Case-Control Studie

2013
The association of plasma lactate with incident cardiovascular outcomes: the ARIC Study.
    American journal of epidemiology, 2013, Aug-01, Volume: 178, Issue:3

    Topics: Alcohol Drinking; Biomarkers; Community-Based Participatory Research; Comorbidity; Coronary Disease;

2013
Association between hyperlactatemia and occult cardiac failure in diabetic patients on maintenance hemodialysis.
    International urology and nephrology, 2014, Volume: 46, Issue:8

    Topics: Aged; Bicarbonates; Blood Gas Analysis; Diabetic Nephropathies; Echocardiography; Female; Heart Fail

2014
Refractory high output heart failure in a patient with primary mitochondrial respiratory chain disease.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:4

    Topics: Adult; Cardiac Output, High; Cardiomyopathies; Heart Failure; Hemodiafiltration; Humans; Lactic Acid

2014
The role of biochemical markers as early indicators of cardiac damage and prognostic parameters of perinatal asphyxia.
    Vojnosanitetski pregled, 2014, Volume: 71, Issue:2

    Topics: Asphyxia Neonatorum; Biomarkers; C-Reactive Protein; Creatine Kinase, MB Form; Heart Failure; Humans

2014
Validation of lactate level as a predictor of early mortality in acute decompensated heart failure patients who entered intensive care unit.
    Journal of cardiology, 2015, Volume: 65, Issue:2

    Topics: Acute Disease; Aged; Biomarkers; Female; Heart Failure; Hospital Mortality; Hospitalization; Humans;

2015
ASIC3 contributes to the blunted muscle metaboreflex in heart failure.
    Medicine and science in sports and exercise, 2015, Volume: 47, Issue:2

    Topics: Acid Sensing Ion Channels; Animals; Blood Pressure; Ganglia, Spinal; Heart Failure; Heart Rate; Lact

2015
Sustained release of milrinone delivered via microparticles in a rodent model of myocardial infarction.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 148, Issue:5

    Topics: Animals; Blood Pressure; Cardiotonic Agents; Cell Adhesion Molecules; Chemistry, Pharmaceutical; Chr

2014
[Extracorporeal membrane oxygenation for the treatment of refractory cardiogenic shock in adults: strategies, results, and predictors of mortality].
    Giornale italiano di cardiologia (2006), 2014, Volume: 15, Issue:10

    Topics: Adult; Aged; Biomarkers; Blood Transfusion; Creatine Kinase; Extracorporeal Membrane Oxygenation; Fe

2014
[Veno-arterial extracorporeal membrane oxygenation system: "leave the chest closed!"].
    Giornale italiano di cardiologia (2006), 2014, Volume: 15, Issue:10

    Topics: Extracorporeal Membrane Oxygenation; Female; Heart Failure; Humans; Lactic Acid; Male; Shock, Cardio

2014
Successful Treatment of Aluminium Phosphide Poisoning by Extracorporeal Membrane Oxygenation.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:3

    Topics: Adult; Aluminum Compounds; Echocardiography; Extracorporeal Membrane Oxygenation; Heart Failure; Hum

2016
Late gadolinium enhancement on cardiac magnetic resonance predicts coronary vasomotor abnormality and myocardial lactate production in patients with chronic heart failure.
    Heart and vessels, 2016, Volume: 31, Issue:12

    Topics: Acetylcholine; Adult; Aged; Biomarkers; Blood Flow Velocity; Cardiomyopathies; Chi-Square Distributi

2016
Prognostic significance of endogenous erythropoietin in long-term outcome of patients with acute decompensated heart failure.
    European journal of heart failure, 2016, Volume: 18, Issue:7

    Topics: Acute Disease; Aged; Aged, 80 and over; Anemia; Cause of Death; Cohort Studies; Disease Progression;

2016
[In Process Citation].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2016, Volume: 111, Issue:4

    Topics: Critical Care; Heart Failure; Humans; Lactic Acid; Prognosis; Pulmonary Embolism; Risk Assessment; S

2016
Western diet impairs metabolic remodelling and contractile efficiency in cardiac hypertrophy.
    Cardiovascular research, 2009, Feb-15, Volume: 81, Issue:3

    Topics: Acyl-CoA Dehydrogenase; Animals; CD36 Antigens; Diabetes Mellitus, Type 2; Dietary Fats; Disease Mod

2009
Assessment of a new experimental model of isolated right ventricular failure.
    Artificial organs, 2009, Volume: 33, Issue:3

    Topics: Animals; Disease Models, Animal; Dogs; Echocardiography; Ethanol; Heart; Heart Failure; Hemodynamics

2009
Analysis of 6-minute walk test safety in pre-heart transplantation patients.
    Arquivos brasileiros de cardiologia, 2009, Volume: 92, Issue:4

    Topics: Arrhythmias, Cardiac; Elective Surgical Procedures; Epidemiologic Methods; Exercise Test; Female; He

2009
Ghrelin improves disturbed myocardial energy metabolism in rats with heart failure induced by isoproterenol.
    Journal of peptide science : an official publication of the European Peptide Society, 2010, Volume: 16, Issue:8

    Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Eating; Echocardiography; Energy Metabolism;

2010
Assessment of metabolic phenotypes in patients with non-ischemic dilated cardiomyopathy undergoing cardiac resynchronization therapy.
    Journal of cardiovascular translational research, 2010, Volume: 3, Issue:6

    Topics: Adenosine Triphosphate; Adult; Aged; Amino Acids; Biomarkers; Blood Glucose; Cardiac Resynchronizati

2010
Comparison of three methods to identify the anaerobic threshold during maximal exercise testing in patients with chronic heart failure.
    American journal of physical medicine & rehabilitation, 2012, Volume: 91, Issue:2

    Topics: Anaerobic Threshold; Exercise Test; Exercise Tolerance; Female; Heart Failure; Heart Rate; Humans; L

2012
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
    Cardiovascular research, 2013, Mar-15, Volume: 97, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hy

2013
Heparin-binding protein: an early indicator of critical illness and predictor of outcome in cardiac arrest.
    Resuscitation, 2013, Volume: 84, Issue:7

    Topics: Aged; Antimicrobial Cationic Peptides; APACHE; Biomarkers; Blood Proteins; Carrier Proteins; Female;

2013
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure.
    Circulation, 2002, Jul-30, Volume: 106, Issue:5

    Topics: Acetyl-CoA Carboxylase; Acyl-CoA Dehydrogenase; Animals; Carbon Isotopes; Carbon Radioisotopes; Carb

2002
Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure.
    Circulation research, 2002, Aug-23, Volume: 91, Issue:4

    Topics: Acetanilides; Animals; Cardiotonic Agents; Chronic Disease; Coronary Circulation; Disease Models, An

2002
Effect of myocardial volume overload and heart failure on lactate transport into isolated cardiac myocytes.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:3

    Topics: Animals; Biological Transport, Active; Blotting, Western; Body Weight; Buffers; Butyrates; Cell Sepa

2003
Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs.
    American journal of respiratory and critical care medicine, 2003, Jun-15, Volume: 167, Issue:12

    Topics: Animals; Blood Gas Analysis; Capillary Leak Syndrome; Disease Models, Animal; Echocardiography; Func

2003
Prognostic usefulness of an increase of N-terminal proatrial natriuretic peptide during exercise in patients with chronic heart failure.
    The American journal of cardiology, 2003, Jul-01, Volume: 92, Issue:1

    Topics: Aged; Atrial Natriuretic Factor; Exercise; Exercise Test; Heart Failure; Humans; Interleukin-8; Lact

2003
Exercise responses of elderly patients with diastolic versus systolic heart failure.
    Medicine and science in sports and exercise, 2003, Volume: 35, Issue:9

    Topics: Aged; Aging; Anaerobic Threshold; Diastole; Exercise; Exercise Tolerance; Female; Heart Failure; Hum

2003
[Lactic acid and ketones in the blood in congestive heart disease treated by prolonged fast].
    Folia cardiologica, 1952, Volume: 11, Issue:4

    Topics: Fasting; Heart Failure; Humans; Ketone Bodies; Ketones; Khellin; Lactic Acid

1952
[Triphosphoric ester of thiamine and its action on hyperlactacidemia in congestive heart failure].
    Giornale di clinica medica, 1953, Volume: 34, Issue:5

    Topics: Esters; Heart Failure; Humans; Lactic Acid; Thiamine

1953
[Significance of changes in blood lactic and pyruvic acid levels in cardiac decompensation].
    Magyar belorvosi archivum (1955), 1956, Volume: 9, Issue:4

    Topics: Heart Failure; Lactic Acid; Pyruvates; Pyruvic Acid

1956
[Significance of changes in blood lactic and pyruvic acid levels in cardiac decompensation].
    Magyar belorvosi archivum (1955), 1956, Volume: 9, Issue:4

    Topics: Heart Failure; Lactic Acid; Pyruvates; Pyruvic Acid

1956
[Significance of changes in blood lactic and pyruvic acid levels in cardiac decompensation].
    Magyar belorvosi archivum (1955), 1956, Volume: 9, Issue:4

    Topics: Heart Failure; Lactic Acid; Pyruvates; Pyruvic Acid

1956
[Significance of changes in blood lactic and pyruvic acid levels in cardiac decompensation].
    Magyar belorvosi archivum (1955), 1956, Volume: 9, Issue:4

    Topics: Heart Failure; Lactic Acid; Pyruvates; Pyruvic Acid

1956
[Comparative studies on the behavior of the lactic acid level in therapy of cardiac insufficiency].
    Medizinische Klinik, 1959, Jan-02, Volume: 54, Issue:1

    Topics: Heart Failure; Humans; Lactic Acid

1959
[Lactacidemia and ascorbic acid in cardiac insufficiency; therapeutic conclusions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1959, May-01, Volume: 14, Issue:9

    Topics: Ascorbic Acid; Heart Failure; Humans; Lactic Acid; Vitamins

1959
[The influence of cocarboxylase on pyruvic and lactic acids in blood in cardiac disorders].
    Wiener medizinische Wochenschrift (1946), 1959, Dec-05, Volume: 109

    Topics: Heart Diseases; Heart Failure; Humans; Lactates; Lactic Acid; Pyruvates; Thiamine Pyrophosphate

1959
Restoration of sarcoplasmic reticulum protein level by thyroid hormone contributes to partial improvement of myocardial function, but not to glucose metabolism in an early failing heart.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 24, Issue:4

    Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Disease Models, Animal; Disease Progression;

2003
Mechanical versus medical bridge to transplantation in children. What is the best timing for mechanical bridge?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:4

    Topics: Adolescent; Cardiotonic Agents; Child; Child, Preschool; Creatinine; Extracorporeal Membrane Oxygena

2004
Studies on intragastric PCO2 at rest and during exercise as a marker of intestinal perfusion in patients with chronic heart failure.
    European journal of heart failure, 2004, Volume: 6, Issue:4

    Topics: Biomarkers; Carbon Dioxide; Chronic Disease; Exercise; Exercise Test; Female; Germany; Heart Failure

2004
Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:4

    Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Dogs; Down-Regulation; Fatty Acids, Nonest

2004
Surgery for mesenteric infarction: prognostic factors associated with early death within 72 hours.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:6

    Topics: Aged; Aspartate Aminotransferases; Calcitonin; Calcitonin Gene-Related Peptide; Cholesterol; Female;

2004
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:6

    Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag

2004
Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 99, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Electric Stimulation; Heart

2005
Mechanical circulatory support in infants and adults with the MEDOS/HIA assist device.
    Artificial organs, 2005, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Bilirubin; Child; Child, Preschool; Creatinine; Female; Heart Failure; Hear

2005
Differential cardiovascular responses during weaning failure: effects on tissue oxygenation and lactate.
    Intensive care medicine, 2005, Volume: 31, Issue:12

    Topics: Aged; Aged, 80 and over; Cardiac Output; Cardiac Output, Low; Case-Control Studies; Female; Heart Fa

2005
Weaning failure from cardiovascular origin.
    Intensive care medicine, 2005, Volume: 31, Issue:12

    Topics: Cardiac Output, Low; Heart Failure; Humans; Lactic Acid; Oxygen; Pulmonary Disease, Chronic Obstruct

2005
A pilot study to assess the feasibility of a submaximal exercise test to measure individual response to cardiac medication in dogs with acquired heart failure.
    Veterinary research communications, 2007, Volume: 31, Issue:6

    Topics: Animals; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Cardiotonic Agents; Dog Disease

2007
Usefulness of BNP-administration in cardiac surgery: animal model.
    Scandinavian cardiovascular journal : SCJ, 2007, Volume: 41, Issue:5

    Topics: Animals; Cardiopulmonary Bypass; Catecholamines; Creatine Kinase; Female; Heart Failure; Hemodynamic

2007
Myocardial metabolic and hemodynamic effects of intravenous MDL-17,043, a new cardiotonic drug, in patients with chronic severe heart failure.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Aged; Blood Flow Velocity; Cardiotonic Agents; Chronic Disease; Enoximone; Female; Heart Failure; He

1984
Acute haemodynamic and myocardial metabolic effects of intravenous urapidil in severe heart failure.
    European heart journal, 1984, Volume: 5, Issue:9

    Topics: Aged; Antihypertensive Agents; Cardiac Output; Coronary Circulation; Electrocardiography; Energy Met

1984
Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts.
    Circulation research, 1983, Volume: 53, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cricetinae; Energy Metabolism; He

1983
[Status of several types of tissue metabolism at rest and during functional tests in patients in the initial stage of heart failure].
    Kardiologiia, 1984, Volume: 24, Issue:3

    Topics: Acid-Base Equilibrium; Adult; Aged; Exercise Test; Female; Glycolysis; Heart Failure; Humans; Lactat

1984
[Peripheral tissue oxygenation in patients with congestive heart failure].
    Acta medica portuguesa, 1983, Volume: 4, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Diphosphoglyceric Acids; Erythrocytes; Female; Heart Failure; H

1983
Effect of hydralazine on perfusion and metabolism in the leg during upright bicycle exercise in patients with heart failure.
    Circulation, 1983, Volume: 68, Issue:2

    Topics: Aged; Cardiac Output; Exercise Test; Female; Heart Failure; Humans; Hydralazine; Lactates; Lactic Ac

1983
[Hemodynamic and metabolic effects of using sodium nitroprusside in acute myocardial infarct complicated by left ventricular failure].
    Kardiologiia, 1982, Volume: 22, Issue:9

    Topics: Acute Disease; Adult; Aged; Blood Glucose; Creatine Kinase; Electrocardiography; Ferricyanides; Hear

1982
A study on the function of some subcellular systems of the sheep myocardium during gousiekte. I. The energy production system.
    The Onderstepoort journal of veterinary research, 1982, Volume: 49, Issue:4

    Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Heart Failure; Lactates; Lactic Acid; Male; Mito

1982
Acute substantial benefit of inotropic therapy with amrinone on exercise hemodynamics and metabolism in severe congestive heart failure.
    Circulation, 1981, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Aminopyridines; Amrinone; Blood Pressure; Exercise Test; Female; Heart Failure; H

1981
Effects of sodium nitroprusside upon cardiac work, efficiency, and substrate extraction in severe left ventricular failure.
    British heart journal, 1981, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Ferricyanides; Heart; Heart Failure; Hemodynamics; Humans; Lactates; Lactic Acid;

1981
Effects of isosorbide dinitrate and hydralazine on regional metabolic responses to arm exercise in patients with heart failure.
    The American journal of cardiology, 1981, Volume: 48, Issue:5

    Topics: Adult; Arm; Female; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Lactates; Lactic Acid;

1981
Effects of spiraprilat, an angiotensin-converting enzyme inhibitor, on anesthetized dogs in a new model of acute left ventricular failure.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4

    Topics: Adenosine Triphosphate; Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressur

1993
Ventilatory and heart rate responses after exercise in chronic cardiac failure.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:2

    Topics: Aged; Carbon Dioxide; Exercise Test; Heart Failure; Heart Rate; Humans; Lactates; Lactic Acid; Lung;

1994
Effect of physical training on exercise-induced hyperkalemia in chronic heart failure. Relation with ventilation and catecholamines.
    Circulation, 1994, Volume: 89, Issue:3

    Topics: Epinephrine; Exercise Test; Exercise Therapy; Exercise Tolerance; Heart Failure; Homeostasis; Humans

1994
Effect of enoximone alone and in combination with metoprolol on myocardial function and energetics in severe congestive heart failure: improvement in hemodynamic and metabolic profile.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:3

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Coronary Circulation; Drug Synergism; Drug Therapy, Com

1993
O2 uptake kinetics in response to exercise. A measure of tissue anaerobiosis in heart failure.
    Chest, 1993, Volume: 103, Issue:3

    Topics: Acidosis, Lactic; Adult; Aged; Anaerobiosis; Catecholamines; Energy Metabolism; Exercise; Exercise T

1993
Ammonia response to exercise in patients with congestive heart failure.
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Ammonia; Exercise; Exercise Test; Female; Heart Failure; Humans; Hypoxanthin

1996
Skeletal muscle metabolism during exercise in patients with chronic heart failure.
    Heart (British Cardiac Society), 1996, Volume: 76, Issue:1

    Topics: Adenosine Triphosphate; Aged; Cardiac Catheterization; Exercise; Exercise Test; Female; Glucose; Glu

1996
Effects of heart rate on coronary circulation and external mechanical efficiency in elderly hypertensive patients with left ventricular hypertrophy.
    Clinical cardiology, 1996, Volume: 19, Issue:8

    Topics: Aged; Analysis of Variance; Coronary Circulation; Heart Failure; Heart Rate; Hemodynamics; Humans; H

1996
Abnormalities of skeletal muscle metabolism in patients with chronic heart failure: evidence that they are present at rest.
    Heart (British Cardiac Society), 1997, Volume: 77, Issue:2

    Topics: Adult; Aged; Ammonia; Female; Forearm; Hand Strength; Heart Failure; Humans; Lactic Acid; Male; Midd

1997
Improved ventilation and decreased sympathetic stress in chronic heart failure patients following local endurance training with leg muscles.
    Journal of cardiac failure, 1997, Volume: 3, Issue:1

    Topics: Adult; Aged; Atrial Natriuretic Factor; Epinephrine; Exercise Therapy; Exercise Tolerance; Heart Fai

1997
Renal circulation and cellular metabolism during left ventricular assisted circulation: comparison study of pulsatile and nonpulsatile assists.
    Artificial organs, 1997, Volume: 21, Issue:7

    Topics: Animals; beta 2-Microglobulin; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Anim

1997
Non-invasive measurement of cardiac output and ventricular ejection fractions in chronic cardiac failure: relationship to impaired exercise tolerance.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:3

    Topics: Adult; Aged; Cardiac Output; Chronic Disease; Exercise Test; Exercise Tolerance; Heart Failure; Hear

1997
Skeletal muscle function at low work level as a model for daily activities in patients with chronic heart failure.
    European heart journal, 1997, Volume: 18, Issue:10

    Topics: Activities of Daily Living; Blood Flow Velocity; Blood Gas Analysis; Chronic Disease; Energy Metabol

1997
Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:2

    Topics: Acute Disease; Anesthesia; Animals; Calcium Channel Blockers; Dogs; Female; Heart Failure; Hemodynam

1998
Undetected cardiogenic shock in patients with congestive heart failure presenting to the emergency department.
    The American journal of cardiology, 1998, Oct-01, Volume: 82, Issue:7

    Topics: Aged; Case-Control Studies; Emergencies; Emergency Treatment; Heart Failure; Humans; Lactic Acid; Mi

1998
Maintained exercise pressor response in heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Exercise; Female; Glycolysis; Heart Failure;

1998
Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog.
    Circulation research, 1998, Nov-16, Volume: 83, Issue:10

    Topics: Animals; Blood Pressure; Carbon Dioxide; Consciousness; Diastole; Dogs; Fatty Acids, Nonesterified;

1998
Sympathetic nervous response relative to the adenosine triphosphate supply-demand imbalance during exercise is augmented in patients with heart failure.
    Chest, 1998, Volume: 114, Issue:5

    Topics: Adenosine Diphosphate; Anaerobic Threshold; Exercise Test; Female; Heart Failure; Humans; Hypoxanthi

1998
Regulation of myocardial blood flow by oxygen consumption is maintained in the failing heart during exercise.
    Circulation research, 1999, Mar-05, Volume: 84, Issue:4

    Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Echocardiography; Heart; Heart Failure; Heart

1999
Female-related skeletal muscle phenotype in patients with moderate chronic heart failure before and after dynamic exercise training.
    Cardiovascular research, 1999, Volume: 42, Issue:1

    Topics: Adult; Aged; Biopsy, Needle; Case-Control Studies; Chronic Disease; Exercise Test; Female; Heart Fai

1999
Non-invasive measurement of stroke volume during exercise in heart failure patients.
    Clinical science (London, England : 1979), 2000, Volume: 98, Issue:5

    Topics: Adult; Aged; Anaerobic Threshold; Cardiac Output; Exercise; Exercise Test; Female; Heart Failure; Hu

2000
Beneficial effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor in rats with heart failure following myocardial infarction.
    European journal of pharmacology, 2000, May-03, Volume: 395, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Body Weight; Cardio

2000
Gas exchange responses to continuous incremental cycle ergometry exercise in primary pulmonary hypertension in humans.
    European journal of applied physiology, 2000, Volume: 83, Issue:1

    Topics: Acidosis, Lactic; Adult; Case-Control Studies; Exercise; Exercise Test; Female; Heart Failure; Human

2000
Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock.
    Critical care medicine, 2000, Volume: 28, Issue:11

    Topics: Acid-Base Equilibrium; Blood Volume; Cardiac Output; Critical Care; Heart Failure; Hemodynamics; Hem

2000
Skeletal muscle characteristics, muscle strength and thigh muscle area in patients before and after cardiac transplantation.
    European journal of heart failure, 2001, Volume: 3, Issue:1

    Topics: Case-Control Studies; Citrate (si)-Synthase; Exercise Test; Female; Heart Failure; Heart Transplanta

2001
High lactate predicts the failure of intraaortic balloon pumping after cardiac surgery.
    The Annals of thoracic surgery, 2001, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Coronary Artery Bypass; Female; Heart Failure; Heart Valve Prosthesis Impla

2001
Effect of a myocardial volume overload on lactate transport in skeletal muscle sarcolemmal vesicles.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:1

    Topics: Animals; Cardiac Volume; Carrier Proteins; Citrate (si)-Synthase; Female; Heart Failure; Lactic Acid

2001
Serum lactates are not predictive of heart failure severity in status I cardiac transplant candidates.
    The Journal of cardiovascular surgery, 2001, Volume: 42, Issue:6

    Topics: Biomarkers; Cardiac Catheterization; Cardiomyopathies; Critical Care; Heart Failure; Heart Transplan

2001
Cardiac energetics in congestive heart failure.
    Circulation, 2002, Feb-12, Volume: 105, Issue:6

    Topics: Animals; Carbohydrate Metabolism; Disease Models, Animal; Energy Metabolism; Glycolysis; Heart Failu

2002
Preoperative IABP in high-risk patients reduces postoperative lactate release and subsequent mortality.
    The Annals of thoracic surgery, 2002, Volume: 73, Issue:3

    Topics: Heart Arrest, Induced; Heart Failure; Heart Valve Prosthesis Implantation; Humans; Intra-Aortic Ball

2002
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
    Circulation, 2002, Jul-09, Volume: 106, Issue:2

    Topics: Aged; Aspirin; Bradykinin; Chemoreceptor Cells; Chronic Disease; Cyclooxygenase Inhibitors; Exercise

2002
Determination of plasma lactic acid concentration and specific activity using high-performance liquid chromatography.
    Journal of chromatography, 1991, Aug-23, Volume: 568, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetates; Chromatography, High Pressure Liquid; Heart Failure; Humans; Hydrox

1991
[Hemodynamic characteristics of heart transplant patients in the early postoperative period].
    Zeitschrift fur Kardiologie, 1991, Volume: 80, Issue:11

    Topics: Adult; Epoprostenol; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Lactates; L

1991
[Exercise therapy after acute myocardial infarct and heart failure].
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 8

    Topics: Heart Failure; Hemodynamics; Humans; Lactates; Lactic Acid; Myocardial Infarction; Physical Educatio

1991
[Plasma ANP, noradrenaline, lactate concentrations during standardized ergometric stress in post-infarct patients. Evaluation of myocardial stress function with reference to limits of exercise therapy].
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 8

    Topics: Atrial Natriuretic Factor; Exercise Test; Heart Failure; Hemodynamics; Humans; Lactates; Lactic Acid

1991
Altered skeletal muscle metabolic response to exercise in chronic heart failure. Relation to skeletal muscle aerobic enzyme activity.
    Circulation, 1991, Volume: 84, Issue:4

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Citrate (si)-Synthase; Exercise; Exercise Test; Heart Failure; Hex

1991
Catecholamine metabolism in heart failure patients and healthy control subjects.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:12

    Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Dilated; Catecholamines; Exercise; Half-Life; Heart Fai

1990
[Heart surgery interventions in risk patients. New possibilities for improving therapeutic results].
    Zentralblatt fur Chirurgie, 1990, Volume: 115, Issue:14

    Topics: Adult; Cardiac Output; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Energy Metaboli

1990
Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure.
    British heart journal, 1990, Volume: 64, Issue:6

    Topics: Adenosine Triphosphate; Adult; Aged; Chronic Disease; Exercise Test; Female; Glycolysis; Heart Failu

1990
A comparison of methodologies in detection of the anaerobic threshold.
    Circulation, 1990, Volume: 81, Issue:1 Suppl

    Topics: Aged; Anaerobic Threshold; Exercise Test; Heart Failure; Humans; Lactates; Lactic Acid; Male; Models

1990
The anaerobic threshold in chronic heart failure. Relation to blood lactate, ventilatory basis, reproducibility, and response to exercise training.
    Circulation, 1990, Volume: 81, Issue:1 Suppl

    Topics: Anaerobic Threshold; Exercise Test; Exercise Therapy; Heart Failure; Hemodynamics; Humans; Lactates;

1990
Oxygen uptake/supply dependency. Effects of short-term dobutamine infusion.
    The American review of respiratory disease, 1990, Volume: 142, Issue:1

    Topics: Acidosis, Lactic; Aged; Bacterial Infections; Dobutamine; Female; Heart Failure; Humans; Lactates; L

1990
Response of the beta-adrenergic system to maximal dynamic exercise in congestive heart failure secondary to idiopathic dilated cardiomyopathy.
    The American journal of cardiology, 1989, Jun-01, Volume: 63, Issue:18

    Topics: Adult; Cardiomyopathy, Dilated; Cyclic AMP; Epinephrine; Exercise; Exercise Test; Female; Heart Fail

1989
Energy metabolism and mechanical function in perfused hearts of Syrian hamsters with dilated or hypertrophic cardiomyopathy.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Carnitine; Coenzyme A; Coronary Circu

1986
Effect of the renin-angiotensin system on limb circulation and metabolism during exercise in patients with heart failure.
    Journal of the American College of Cardiology, 1985, Volume: 6, Issue:3

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Exercise Test; Heart Fail

1985
Direct and indirect assessment of skeletal muscle blood flow in chronic congestive heart failure.
    The American journal of cardiology, 1988, Sep-09, Volume: 62, Issue:8

    Topics: Captopril; Cardiac Output; Heart Failure; Humans; Lactates; Lactic Acid; Milrinone; Muscles; Phospho

1988
Dependence of oxygen consumption on oxygen delivery in patients with chronic congestive heart failure.
    Chest, 1987, Volume: 92, Issue:3

    Topics: Blood Gas Analysis; Heart Failure; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Nitroglycerin;

1987
Sympathetic activation on effort in patients with chronic heart failure. Long term effects of captopril.
    Acta cardiologica, 1988, Volume: 43, Issue:5

    Topics: Adult; Aged; Captopril; Carbon Dioxide; Cardiac Output; Echocardiography; Exercise Test; Heart Failu

1988
[Assessment of the calcium homeostatic state using the double calcium tolerance test].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:12

    Topics: Calcium; Calcium, Dietary; Chronic Disease; Feedback; Heart Failure; Homeostasis; Humans; Hypercalce

1988
Abdominal pain and weakness in an elderly woman.
    Annals of emergency medicine, 1986, Volume: 15, Issue:10

    Topics: Abdomen; Aged; Creatine Kinase; Electrocardiography; Female; Heart Failure; Humans; Isoenzymes; Lact

1986
Effect of the sympathetic nervous system on limb circulation and metabolism during exercise in patients with heart failure.
    Circulation, 1985, Volume: 72, Issue:1

    Topics: Aged; Cardiac Output; Heart Failure; Humans; Lactates; Lactic Acid; Leg; Male; Middle Aged; Oxygen C

1985