lactic acid has been researched along with Gonorrhea in 6 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chappell, BT | 1 |
| Mena, LA | 1 |
| Maximos, B | 1 |
| Mollan, S | 1 |
| Culwell, K | 1 |
| Howard, B | 1 |
| CARPENTER, CM | 1 |
| BAHN, JM | 1 |
| Exley, RM | 2 |
| Wu, H | 1 |
| Shaw, J | 1 |
| Schneider, MC | 1 |
| Smith, H | 2 |
| Jerse, AE | 1 |
| Tang, CM | 2 |
| Gobelet, C | 1 |
| Gerster, JC | 1 |
| Evanchick, CE | 1 |
| Davis, DE | 1 |
| Harrington, TM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2B Double-blind Placebo-controlled Efficacy Trial of EVO100 (Previously Known as Amphora ® Gel) for the Prevention of Acquisition of Urogenital Chlamydia Trachomatis Infection[NCT03107377] | Phase 2/Phase 3 | 860 participants (Actual) | Interventional | 2017-11-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Summary of Coital Events during treatment (NCT03107377)
Timeframe: 16 weeks
| Intervention | Coital Events (Mean) |
|---|---|
| EVO100 | 15.7 |
| Placebo | 16.3 |
Summary of number of applicators used via eDiary (NCT03107377)
Timeframe: 16 weeks
| Intervention | Number of Applicators (Mean) |
|---|---|
| EVO100 | 13.0 |
| Placebo | 13.5 |
Study product adherence (NCT03107377)
Timeframe: 16 weeks
| Intervention | % of sex acts where study product used (Mean) |
|---|---|
| EVO100 | 78.9 |
| Placebo | 78.3 |
Proportion of subjects who experience urogenital CT infection during the study intervention period (incident infection of CT). (NCT03107377)
Timeframe: 16 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| EVO100 | 14 |
| Placebo | 28 |
Proportion of subjects who experience urogenital GC infection during the study intervention period (incident infection of GC). (NCT03107377)
Timeframe: 16 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| EVO100 | 2 |
| Placebo | 9 |
1 review available for lactic acid and Gonorrhea
| Article | Year |
|---|---|
Effect of host lactate on gonococci and meningococci: new concepts on the role of metabolites in pathogenicity.
Topics: Animals; Gonorrhea; Humans; Lactic Acid; Meningitis, Meningococcal; Neisseria gonorrhoeae; Neisseria | 2007 |
1 trial available for lactic acid and Gonorrhea
| Article | Year |
|---|---|
EVO100 prevents chlamydia and gonorrhea in women at high risk of infection.
Topics: Administration, Intravaginal; Adult; Anti-Infective Agents; Chlamydia Infections; Citric Acid; Drug | 2021 |
4 other studies available for lactic acid and Gonorrhea
| Article | Year |
|---|---|
Adaptability of gonococcus to four bacteriostatic agents, sodium sulfathiazole, rivanol lactate, promin, and penicillin.
Topics: Dapsone; Ethacridine; Gonorrhea; Lactates; Lactic Acid; Neisseria; Neisseria gonorrhoeae; Penicillin | 1945 |
Lactate acquisition promotes successful colonization of the murine genital tract by Neisseria gonorrhoeae.
Topics: Animals; Blood Bactericidal Activity; Colony Count, Microbial; Female; Gonorrhea; Lactic Acid; Membr | 2007 |
Synovial fluid lactate levels in septic and non-septic arthritides.
Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Arthritis, Rheumatoid; Gonorrhea; Hemarthrosi | 1984 |
Septic arthritis. Clinical approach to the 'hot joint'.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Child; Diagn | 1986 |