Page last updated: 2024-10-17

lactic acid and Gonorrhea

lactic acid has been researched along with Gonorrhea in 6 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Chappell, BT1
Mena, LA1
Maximos, B1
Mollan, S1
Culwell, K1
Howard, B1
CARPENTER, CM1
BAHN, JM1
Exley, RM2
Wu, H1
Shaw, J1
Schneider, MC1
Smith, H2
Jerse, AE1
Tang, CM2
Gobelet, C1
Gerster, JC1
Evanchick, CE1
Davis, DE1
Harrington, TM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2B Double-blind Placebo-controlled Efficacy Trial of EVO100 (Previously Known as Amphora ® Gel) for the Prevention of Acquisition of Urogenital Chlamydia Trachomatis Infection[NCT03107377]Phase 2/Phase 3860 participants (Actual)Interventional2017-11-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Compliance With EVO100 and Sensitivity Analyses (Part I)

Summary of Coital Events during treatment (NCT03107377)
Timeframe: 16 weeks

InterventionCoital Events (Mean)
EVO10015.7
Placebo16.3

Compliance With EVO100 and Sensitivity Analyses (Part II)

Summary of number of applicators used via eDiary (NCT03107377)
Timeframe: 16 weeks

InterventionNumber of Applicators (Mean)
EVO10013.0
Placebo13.5

Compliance With EVO100 and Sensitivity Analyses (Part III)

Study product adherence (NCT03107377)
Timeframe: 16 weeks

Intervention% of sex acts where study product used (Mean)
EVO10078.9
Placebo78.3

Urogenital CT Infection

Proportion of subjects who experience urogenital CT infection during the study intervention period (incident infection of CT). (NCT03107377)
Timeframe: 16 weeks

InterventionParticipants (Count of Participants)
EVO10014
Placebo28

Urogenital GC Infection

Proportion of subjects who experience urogenital GC infection during the study intervention period (incident infection of GC). (NCT03107377)
Timeframe: 16 weeks

InterventionParticipants (Count of Participants)
EVO1002
Placebo9

Reviews

1 review available for lactic acid and Gonorrhea

ArticleYear
Effect of host lactate on gonococci and meningococci: new concepts on the role of metabolites in pathogenicity.
    Infection and immunity, 2007, Volume: 75, Issue:9

    Topics: Animals; Gonorrhea; Humans; Lactic Acid; Meningitis, Meningococcal; Neisseria gonorrhoeae; Neisseria

2007

Trials

1 trial available for lactic acid and Gonorrhea

ArticleYear
EVO100 prevents chlamydia and gonorrhea in women at high risk of infection.
    American journal of obstetrics and gynecology, 2021, Volume: 225, Issue:2

    Topics: Administration, Intravaginal; Adult; Anti-Infective Agents; Chlamydia Infections; Citric Acid; Drug

2021

Other Studies

4 other studies available for lactic acid and Gonorrhea

ArticleYear
Adaptability of gonococcus to four bacteriostatic agents, sodium sulfathiazole, rivanol lactate, promin, and penicillin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1945, Volume: 60

    Topics: Dapsone; Ethacridine; Gonorrhea; Lactates; Lactic Acid; Neisseria; Neisseria gonorrhoeae; Penicillin

1945
Lactate acquisition promotes successful colonization of the murine genital tract by Neisseria gonorrhoeae.
    Infection and immunity, 2007, Volume: 75, Issue:3

    Topics: Animals; Blood Bactericidal Activity; Colony Count, Microbial; Female; Gonorrhea; Lactic Acid; Membr

2007
Synovial fluid lactate levels in septic and non-septic arthritides.
    Annals of the rheumatic diseases, 1984, Volume: 43, Issue:5

    Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Arthritis, Rheumatoid; Gonorrhea; Hemarthrosi

1984
Septic arthritis. Clinical approach to the 'hot joint'.
    Postgraduate medicine, 1986, Feb-01, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Child; Diagn

1986