lactic acid has been researched along with Glycogen Storage Disease in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Glycogen Storage Disease: A group of inherited metabolic disorders involving the enzymes responsible for the synthesis and degradation of glycogen. In some patients, prominent liver involvement is presented. In others, more generalized storage of glycogen occurs, sometimes with prominent cardiac involvement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fasting glucagon test of 40 patients with hepatic glycogen storage disease (type I, 13 patients; type Ib, 5 patients; type III, 12 patients; type IX (phosphorylase kinase deficiency), 10 patients) has been reviewed." | 7.66 | Value of the glucagon test in screening for hepatic glycogen storage disease. ( Dunger, DB; Leonard, JV, 1982) |
| "The plasma glucose, insulin, glucagon, lactate and amino acid response patterns to glucose and protein meals were examined in 11 patients with type III glycogen storage disease (GSD-III)." | 3.66 | Amino acid disturbances in type III glycogenosis: differences from type I glycogenosis. ( Bashan, N; Coleman, RA; Moses, S; Mushlin, P; Shipp, E; Slonim, AE, 1983) |
| "The fasting glucagon test of 40 patients with hepatic glycogen storage disease (type I, 13 patients; type Ib, 5 patients; type III, 12 patients; type IX (phosphorylase kinase deficiency), 10 patients) has been reviewed." | 3.66 | Value of the glucagon test in screening for hepatic glycogen storage disease. ( Dunger, DB; Leonard, JV, 1982) |
| "The ketosis was reversed by glucagon administration." | 1.27 | Clinical and laboratory observations in a child with hepatic phosphorylase kinase deficiency. ( Brown, BI; Burke, BA; Tuchman, M; Ulstrom, RA, 1986) |
| "Three patients with McArdle's disease exercised for 2 h at 30% VO2max." | 1.27 | The second wind phenomenon in McArdle's disease. ( Binkhorst, RA; Braakhekke, JP; de Bruin, MI; Joosten, EM; Stegeman, DF; Wevers, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Serrano-Lorenzo, P | 1 |
| Rabasa, M | 1 |
| Esteban, J | 1 |
| Hidalgo Mayoral, I | 1 |
| Domínguez-González, C | 1 |
| Blanco-Echevarría, A | 1 |
| Garrido-Moraga, R | 1 |
| Lucia, A | 1 |
| Blázquez, A | 1 |
| Rubio, JC | 1 |
| Palma-Milla, C | 1 |
| Arenas, J | 1 |
| Martín, MA | 1 |
| Regan, JA | 1 |
| Golubski, B | 1 |
| Gilbert, EB | 1 |
| Sullivan, B | 1 |
| McCall, SJ | 1 |
| Sata, SS | 1 |
| Preisler, N | 1 |
| Laforêt, P | 2 |
| Echaniz-Laguna, A | 1 |
| Ørngreen, MC | 1 |
| Lonsdorfer-Wolf, E | 1 |
| Doutreleau, S | 1 |
| Geny, B | 1 |
| Stojkovic, T | 2 |
| Piraud, M | 2 |
| Petit, FM | 1 |
| Vissing, J | 2 |
| Petit, F | 1 |
| Orngreen, MC | 1 |
| Andersen, G | 1 |
| Claeys, KG | 1 |
| Wary, C | 1 |
| Hogrel, JY | 1 |
| Soggia, AP | 1 |
| Correa-Giannella, ML | 1 |
| Fortes, MA | 1 |
| Luna, AM | 1 |
| Pereira, MA | 1 |
| Tarnopolsky, M | 1 |
| Stevens, L | 1 |
| MacDonald, JR | 1 |
| Rodriguez, C | 1 |
| Mahoney, D | 1 |
| Rush, J | 1 |
| Maguire, J | 1 |
| OEI, TL | 1 |
| Bröjer, JT | 1 |
| Essén-Gustavsson, B | 1 |
| Annandale, EJ | 1 |
| Valberg, SJ | 1 |
| Mineo, I | 2 |
| Kono, N | 2 |
| Shimizu, T | 2 |
| Sumi, S | 2 |
| Nonaka, K | 2 |
| Tarui, S | 2 |
| Slonim, AE | 1 |
| Coleman, RA | 1 |
| Moses, S | 1 |
| Bashan, N | 1 |
| Shipp, E | 1 |
| Mushlin, P | 1 |
| Greene, HL | 1 |
| Rumpf, KW | 1 |
| Wagner, H | 1 |
| Kaiser, H | 1 |
| Meinck, HM | 1 |
| Goebel, HH | 1 |
| Scheler, F | 1 |
| Hagberg, JM | 1 |
| Coyle, EF | 1 |
| Carroll, JE | 1 |
| Miller, JM | 1 |
| Martin, WH | 1 |
| Brooke, MH | 1 |
| Dunger, DB | 1 |
| Leonard, JV | 1 |
| Clark, DG | 2 |
| Neville, SD | 2 |
| Brinkman, M | 2 |
| Filsell, OH | 1 |
| de Barsy, T | 1 |
| Hers, HG | 1 |
| Nishimura, Y | 1 |
| Challiss, RA | 1 |
| Leighton, B | 1 |
| Wilson, S | 1 |
| Thurlby, PL | 1 |
| Arch, JR | 1 |
| Biggemann, B | 1 |
| Hilgarth, R | 1 |
| Wendel, U | 1 |
| Smit, GP | 1 |
| Ververs, MT | 1 |
| Belderok, B | 1 |
| Van Rijn, M | 1 |
| Berger, R | 1 |
| Fernandes, J | 1 |
| Tuchman, M | 1 |
| Brown, BI | 1 |
| Burke, BA | 1 |
| Ulstrom, RA | 1 |
| Braakhekke, JP | 1 |
| de Bruin, MI | 1 |
| Stegeman, DF | 1 |
| Wevers, RA | 1 |
| Binkhorst, RA | 1 |
| Joosten, EM | 1 |
| van Riet, W | 1 |
| de Meirsman, J | 1 |
| de Saedeleer, J | 1 |
| Dom, R | 1 |
| Carton, H | 1 |
| van den Heede, J | 1 |
| Bulcke, JA | 1 |
| Hara, N | 1 |
| Yamada, Y | 1 |
| Haynes, WD | 1 |
| Williams, J | 1 |
| Hosking, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Triheptanoin in Adults With McArdle Disease (Glycogen Storage Disease Type V)[NCT02432768] | Phase 2 | 22 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Glycogen Storage Disease
| Article | Year |
|---|---|
Glycogen storage disease.
Topics: Blood Glucose; Glucosephosphate Dehydrogenase Deficiency; Glycogen; Glycogen Storage Disease; Glycog | 1982 |
Normal metabolism and disorders of carbohydrate metabolism.
Topics: Carbohydrate Metabolism; Enzymes; Glucose; Glycogen; Glycogen Storage Disease; Glycolysis; Humans; L | 1990 |
1 trial available for lactic acid and Glycogen Storage Disease
| Article | Year |
|---|---|
[Type I glycogenosis: extending therapy with uncooked cornstarch].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Combined Modality Therapy; Creatinine; Enteral N | 1986 |
23 other studies available for lactic acid and Glycogen Storage Disease
| Article | Year |
|---|---|
Clinical, Biochemical, and Molecular Characterization of Two Families with Novel Mutations in the
Topics: Codon, Nonsense; Dermatitis; Female; Glycogen Storage Disease; Humans; Isoenzymes; Lactate Dehydroge | 2022 |
Glycogenic Hepatopathy Causing Elevated Lactic Acid and Liver Enzymes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Diabetes Mel | 2020 |
Fat and carbohydrate metabolism during exercise in phosphoglucomutase type 1 deficiency.
Topics: Adult; Bicycling; Carbohydrate Metabolism; Exercise Test; Exercise Tolerance; Glucose; Glycogen Stor | 2013 |
Muscle glycogenosis due to phosphoglucomutase 1 deficiency.
Topics: Adult; Ammonia; Exercise; Glycogen Storage Disease; Humans; Lactic Acid; Male; Muscle, Skeletal; Mut | 2009 |
A novel mutation in the glycogen synthase 2 gene in a child with glycogen storage disease type 0.
Topics: Base Sequence; Blood Glucose; Child; Codon, Nonsense; Exons; Fasting; Female; Frameshift Mutation; G | 2010 |
Diagnostic utility of a modified forearm ischemic exercise test and technical issues relevant to exercise testing.
Topics: Adult; Ammonia; Catheterization, Peripheral; Eating; Exercise Test; Forearm; Glycogen Storage Diseas | 2003 |
Hexose monophosphate, pyruvate and lactate in the peripheral blood in glycogen-storage disease type I.
Topics: Glycogen; Glycogen Storage Disease; Hexosephosphates; Hexoses; Humans; Lactates; Lactic Acid; Pyruva | 1962 |
Proglycogen, macroglycogen, glucose, and glucose-6-phosphate concentrations in skeletal muscles of horses with polysaccharide storage myopathy performing light exercise.
Topics: Animals; Biopsy; Creatine Kinase; Female; Glucose; Glucose-6-Phosphate; Glycogen; Glycogen Storage D | 2006 |
A comparative study on glucagon effect between McArdle disease and Tarui disease.
Topics: Adult; Female; Glucagon; Glucose; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; | 1984 |
Amino acid disturbances in type III glycogenosis: differences from type I glycogenosis.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; Fem | 1983 |
Increased ammonia production during forearm ischemic work test in McArdle's disease.
Topics: Ammonia; Forearm; Glycogen; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; Ische | 1981 |
Exercise hyperventilation in patients with McArdle's disease.
Topics: Adult; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; Hyperventilation; | 1982 |
Value of the glucagon test in screening for hepatic glycogen storage disease.
Topics: Blood Glucose; Fasting; Glucagon; Glycogen Storage Disease; Humans; Lactates; Lactic Acid; Liver Dis | 1982 |
Glycogen metabolism in the liver of the neonatal gsd/gsd and control (GSD/GSD) rat.
Topics: Animals; Animals, Newborn; Blood Glucose; Glycogen Storage Disease; Lactates; Lactic Acid; Liver Gly | 1982 |
[Lactate dehydrogenase M subunit deficiency].
Topics: Exercise Test; Glycogen Storage Disease; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; La | 1990 |
An investigation of the beta-adrenoceptor that mediates metabolic responses to the novel agonist BRL28410 in rat soleus muscle.
Topics: Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Glycogen Storage Disease; Heart Ra | 1988 |
Complex carbohydrates in the dietary management of patients with glycogenosis caused by glucose-6-phosphatase deficiency.
Topics: Adolescent; Blood Glucose; Child; Dietary Carbohydrates; Glycogen Storage Disease; Glycogen Storage | 1988 |
Clinical and laboratory observations in a child with hepatic phosphorylase kinase deficiency.
Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Child, Preschool; Glycogen Storage Disease; Histocyto | 1986 |
The second wind phenomenon in McArdle's disease.
Topics: Adaptation, Physiological; Adult; Ammonia; Blood Glucose; Cardiac Output; Electromyography; Fatigue; | 1986 |
Early onset myophosphorylase deficiency (Mc Ardle's disease) with absence of myophosphorylase protein on SDS electrophoresis. The role of the ischemic forearm test.
Topics: Adult; Biopsy; Electromyography; Electrophoresis, Polyacrylamide Gel; Exercise Test; Female; Forearm | 1985 |
Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII.
Topics: Adult; Ammonia; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Glycogen Storage | 1985 |
Effects in vivo of food deprivation and 3-mercaptopicolinate in the glycogen-storage-disease (gsd/gsd) rat.
Topics: Animals; Blood Glucose; Body Weight; Female; Food Deprivation; Glycerol; Glycogen Storage Disease; L | 1985 |
Type V glycogen storage disease.
Topics: Child; Creatine Kinase; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; L | 1985 |