lactic acid has been researched along with Glycogen Storage Disease Type II in 2 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Glycogen Storage Disease Type II: An autosomal recessively inherited glycogen storage disease caused by GLUCAN 1,4-ALPHA-GLUCOSIDASE deficiency. Large amounts of GLYCOGEN accumulate in the LYSOSOMES of skeletal muscle (MUSCLE, SKELETAL); HEART; LIVER; SPINAL CORD; and BRAIN. Three forms have been described: infantile, childhood, and adult. The infantile form is fatal in infancy and presents with hypotonia and a hypertrophic cardiomyopathy (CARDIOMYOPATHY, HYPERTROPHIC). The childhood form usually presents in the second year of life with proximal weakness and respiratory symptoms. The adult form consists of a slowly progressive proximal myopathy. (From Muscle Nerve 1995;3:S61-9; Menkes, Textbook of Child Neurology, 5th ed, pp73-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glycogenosis type II, or Pompe Disease, is a lysosomal storage disease caused by the deficiency of acid alpha-glucosidase (GAA), leading to glycogen accumulation in muscles." | 1.42 | Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenosis Type II Fibroblasts. ( Bortot, B; De Martino, E; Dolcetta, D; Emiliani, C; Forni, F; Magini, A; Ruozi, B; Severini, GM; Tancini, B; Tosi, G; Urbanelli, L; Vandelli, MA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tancini, B | 1 |
| Tosi, G | 1 |
| Bortot, B | 1 |
| Dolcetta, D | 1 |
| Magini, A | 1 |
| De Martino, E | 1 |
| Urbanelli, L | 1 |
| Ruozi, B | 1 |
| Forni, F | 1 |
| Emiliani, C | 1 |
| Vandelli, MA | 1 |
| Severini, GM | 1 |
| Umpleby, AM | 1 |
| Trend, PS | 1 |
| Chubb, D | 1 |
| Conaglen, JV | 1 |
| Williams, CD | 1 |
| Hesp, R | 1 |
| Scobie, IN | 1 |
| Wiles, CM | 1 |
| Spencer, G | 1 |
| Sönksen, PH | 1 |
1 trial available for lactic acid and Glycogen Storage Disease Type II
| Article | Year |
|---|---|
The effect of a high protein diet on leucine and alanine turnover in acid maltase deficiency.
Topics: Adult; Alanine; alpha-Glucosidases; Clinical Trials as Topic; Dietary Proteins; Female; Follow-Up St | 1989 |
1 other study available for lactic acid and Glycogen Storage Disease Type II
| Article | Year |
|---|---|
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenosis Type II Fibroblasts.
Topics: alpha-Glucosidases; Cells, Cultured; Drug Delivery Systems; Fibroblasts; Glycogen Storage Disease Ty | 2015 |