Page last updated: 2024-10-17

lactic acid and Genetic Predisposition

lactic acid has been researched along with Genetic Predisposition in 22 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Genetic factors play a role in the development of lactic acidosis after OLT."7.78The association of promoter gene polymorphisms of the tumor necrosis factor-α and interleukin-10 with severity of lactic acidosis during liver transplantation surgery. ( Abouelfetoh, F; Baz, H; Farahat, O; Labib, D; Mokhtar, A; Salah, M, 2012)
"Genetic factors play a role in the development of lactic acidosis after OLT."3.78The association of promoter gene polymorphisms of the tumor necrosis factor-α and interleukin-10 with severity of lactic acidosis during liver transplantation surgery. ( Abouelfetoh, F; Baz, H; Farahat, O; Labib, D; Mokhtar, A; Salah, M, 2012)
"Clear cell renal cell carcinoma (ccRCC) is the most common pathological subtype of kidney cancer."2.48Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. ( Burrell, RA; Dykema, K; Endesfelder, D; Gerlinger, M; Howell, M; Jiang, M; Kelly, G; Larkin, J; Martinez, P; Patard, JJ; Rioux-Leclercq, N; Santos, CR; Saunders, RE; Spencer-Dene, B; Stamp, G; Swanton, C; Vetter, M, 2012)
"Specific treatment of mitochondrial diseases is in its infancy and is a major challenge for pediatric medicine."2.44Disorders of mitochondrial function. ( Debray, FG; Lambert, M; Mitchell, GA, 2008)
"The pathophysiology of febrile seizures remains unclear."1.48Interleukin-4 and tumor necrosis factor-alpha levels in children with febrile seizures. ( Bae, SH; Choi, J; Ha, J; Kim, K; Kim, SJ; Kim, SN; Kwak, BO; Kwon, A; Lee, R; Son, JS, 2018)
"PDHc deficiency was demonstrated in muscle and fibroblasts without detectable PDHA1 mutations."1.36Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. ( Briones, P; Font, A; Pineda, M; Quintana, E; Ribes, A; Tort, F; Vilaseca, MA, 2010)
"Lactic acid levels were documented at five different time points: 10 min after beginning of cardiopulmonary bypass, 40 min after cardiopulmonary bypass termination, and 30 min, 8h, and 16 h after the surgery."1.33IL-10 and TNF-beta gene polymorphisms have no major influence on lactate levels after cardiac surgery. ( Brezina, A; Hubacek, JA; Kellovsky, P; Pirk, J; Poledne, R; Riha, H, 2006)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's5 (22.73)29.6817
2010's12 (54.55)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Yuan, Y1
Sun, L2
Wang, X2
Chen, J1
Jia, M1
Zou, Y1
Sa, H1
Cai, Y1
Xu, Y2
Sun, C1
Guo, Y1
Li, H1
Ma, K1
Ye, Z1
Wu, C1
Zhang, N1
Du, L1
Cao, Q1
Huang, X1
Tang, J1
Wang, Q1
Li, F1
Zhou, C1
Xu, Q1
Xiong, X1
Kijlstra, A1
Qin, N1
Yang, P1
Gupta, JK1
Care, A1
Goodfellow, L1
Alfirevic, Z1
Lian, LY1
Müller-Myhsok, B1
Alfirevic, A1
Phelan, MM1
Wei, YL1
Tian, Q1
Zhao, XX1
Qiu, GZ1
Ha, J1
Choi, J1
Kwon, A1
Kim, K1
Kim, SJ1
Bae, SH1
Son, JS1
Kim, SN1
Kwak, BO1
Lee, R1
Pacheu-Grau, D1
Callegari, S1
Emperador, S1
Thompson, K1
Aich, A1
Topol, SE1
Spencer, EG1
McFarland, R1
Ruiz-Pesini, E1
Torkamani, A1
Taylor, RW1
Montoya, J1
Rehling, P1
Zhang, Y1
Wang, T1
Li, X1
Ma, Y1
Akasaka, T1
Hokimoto, S1
Sueta, D1
Tabata, N1
Sakamoto, K1
Yamamoto, E1
Yamamuro, M1
Tsujita, K1
Kojima, S1
Kaikita, K1
Kajiwara, A1
Morita, K1
Oniki, K1
Saruwatari, J1
Nakagawa, K1
Ogata, Y1
Ogawa, H1
Cordani, M1
Pacchiana, R1
Butera, G1
D'Orazi, G1
Scarpa, A1
Donadelli, M1
Dewulf, JP1
Barrea, C1
Vincent, MF1
De Laet, C1
Van Coster, R1
Seneca, S1
Marie, S1
Nassogne, MC1
Debray, FG1
Lambert, M1
Mitchell, GA1
Dela, F1
Stallknecht, B1
Quintana, E1
Pineda, M1
Font, A1
Vilaseca, MA1
Tort, F1
Ribes, A1
Briones, P1
Gerlinger, M1
Santos, CR1
Spencer-Dene, B1
Martinez, P1
Endesfelder, D1
Burrell, RA1
Vetter, M1
Jiang, M1
Saunders, RE1
Kelly, G1
Dykema, K1
Rioux-Leclercq, N1
Stamp, G1
Patard, JJ1
Larkin, J1
Howell, M1
Swanton, C1
Farahat, O1
Salah, M1
Mokhtar, A1
Abouelfetoh, F1
Labib, D1
Baz, H1
Hassanzadeh, M1
Gilanpour, H1
Charkhkar, S1
Buyse, J1
Decuypere, E1
Riha, H1
Hubacek, JA1
Poledne, R1
Kellovsky, P1
Brezina, A1
Pirk, J1
Sperl, W1
Jesina, P1
Zeman, J1
Mayr, JA1
Demeirleir, L1
VanCoster, R1
Pícková, A1
Hansíková, H1
Houst'ková, H1
Krejcík, Z1
Koch, J1
Smet, J1
Muss, W1
Holme, E1
Houstek, J1
Beauchamp, NJ1
Taybert, J1
Champion, MP1
Layet, V1
Heinz-Erian, P1
Dalton, A1
Tanner, MS1
Pronicka, E1
Sharrard, MJ1
Lockette, W1
Kirkland, K1
Farrow, S1
Griez, E1
Schruers, K1
Balasubramanyam, A1
McKay, S1
Nadkarni, P1
Rajan, AS1
Garza, A1
Pavlik, V1
Herd, JA1
Jahoor, F1
Reeds, PJ1

Reviews

4 reviews available for lactic acid and Genetic Predisposition

ArticleYear
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis.
    Cancer letters, 2016, 07-01, Volume: 376, Issue:2

    Topics: Animals; Cell Communication; Cell Movement; Cytokines; Extracellular Matrix; Genetic Predisposition

2016
Disorders of mitochondrial function.
    Current opinion in pediatrics, 2008, Volume: 20, Issue:4

    Topics: Child; Citric Acid Cycle; DNA, Mitochondrial; Genetic Predisposition to Disease; Humans; Lactic Acid

2008
Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target.
    The Journal of pathology, 2012, Volume: 227, Issue:2

    Topics: Apoptosis; Carcinoma, Renal Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell

2012
Experimental pathophysiology of panic.
    Journal of psychosomatic research, 1998, Volume: 45, Issue:6

    Topics: Carbon Dioxide; Female; Genetic Predisposition to Disease; Humans; Lactic Acid; Male; Models, Biolog

1998

Other Studies

18 other studies available for lactic acid and Genetic Predisposition

ArticleYear
Identification of a new
    Future oncology (London, England), 2019, Volume: 15, Issue:36

    Topics: Alternative Splicing; Animals; Base Sequence; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferat

2019
Altered gut microbiome composition in patients with Vogt-Koyanagi-Harada disease.
    Gut microbes, 2020, 05-03, Volume: 11, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Animals; Biodiversity; Butyrates; Disease Models, Animal; DNA, Bacte

2020
Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach.
    Bioscience reports, 2021, 09-30, Volume: 41, Issue:9

    Topics: Adult; Biomarkers; Case-Control Studies; Female; Genetic Predisposition to Disease; Genome-Wide Asso

2021
Association between MFN2 gene polymorphisms and the risk and prognosis of acute liver failure: a case-control study in a Chinese population.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, May-15, Volume: 50, Issue:6

    Topics: Adult; Ammonia; Asian People; Case-Control Studies; China; Female; Gene Frequency; Genetic Predispos

2017
Interleukin-4 and tumor necrosis factor-alpha levels in children with febrile seizures.
    Seizure, 2018, Volume: 58

    Topics: Biomarkers; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Humans; Interleukin-

2018
Mutations of the mitochondrial carrier translocase channel subunit TIM22 cause early-onset mitochondrial myopathy.
    Human molecular genetics, 2018, 12-01, Volume: 27, Issue:23

    Topics: Carrier Proteins; Child; DNA, Mitochondrial; Exome Sequencing; Female; Fibroblasts; Genetic Predispo

2018
The evaluation of neural and vascular hyper-reactivity for sensitive skin.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2016, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Capsaicin; Female; Genetic Predisposition to Disease; Humans; Hyperalgesia; Lacti

2016
Sex differences in the impact of CYP2C19 polymorphisms and low-grade inflammation on coronary microvascular disorder.
    American journal of physiology. Heart and circulatory physiology, 2016, 06-01, Volume: 310, Issue:11

    Topics: Aged; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square Distribution; Coronary Artery

2016
Evidence of a wide spectrum of cardiac involvement due to ACAD9 mutations: Report on nine patients.
    Molecular genetics and metabolism, 2016, Volume: 118, Issue:3

    Topics: Acyl-CoA Dehydrogenases; Adult; Child; Female; Genetic Predisposition to Disease; Heart Diseases; Hu

2016
Effect of physical training on insulin secretion and action in skeletal muscle and adipose tissue of first-degree relatives of type 2 diabetic patients.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 299, Issue:1

    Topics: Adipose Tissue; Adult; Blood Glucose; Body Composition; C-Peptide; Diabetes Mellitus, Type 2; Exerci

2010
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Acidosis, Lactic; Adult; Amino Acid Sequence; Base Sequence; Biomarkers; Blepharoptosis; Cells, Cult

2010
The association of promoter gene polymorphisms of the tumor necrosis factor-α and interleukin-10 with severity of lactic acidosis during liver transplantation surgery.
    Transplantation proceedings, 2012, Volume: 44, Issue:5

    Topics: Acidosis, Lactic; Adult; Biomarkers; Egypt; Female; Genetic Predisposition to Disease; Heterozygote;

2012
Anatomical parameters of cardiopulmonary system in three different lines of chickens: further evidence for involvement in ascites syndrome.
    Avian pathology : journal of the W.V.P.A, 2005, Volume: 34, Issue:3

    Topics: Aging; Animals; Ascites; Body Weight; Cardiovascular System; Chickens; Genetic Predisposition to Dis

2005
IL-10 and TNF-beta gene polymorphisms have no major influence on lactate levels after cardiac surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 30, Issue:1

    Topics: Adult; Aged; Biomarkers; Coronary Artery Bypass; Female; Gene Frequency; Genetic Predisposition to D

2006
Deficiency of mitochondrial ATP synthase of nuclear genetic origin.
    Neuromuscular disorders : NMD, 2006, Volume: 16, Issue:12

    Topics: Adenosine Triphosphate; Adolescent; Age of Onset; Cardiomyopathy, Hypertrophic, Familial; Cell Nucle

2006
High frequency of missense mutations in glycogen storage disease type VI.
    Journal of inherited metabolic disease, 2007, Volume: 30, Issue:5

    Topics: Amino Acid Sequence; Animals; Blood Glucose; Child, Preschool; DNA Mutational Analysis; Exons; Femal

2007
Alpha 2-adrenergic agonists increase cellular lactate efflux.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Body Temperature Regulation; Cells, Cultured; Cerebrovascular Di

1996
Ethnicity affects the postprandial regulation of glycogenolysis.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adult; Asian People; Blood Glucose; Carbon Isotopes; Diabetes Mellitus, Type 2; Energy Metabolism; G

1999