Page last updated: 2024-10-17

lactic acid and Funnel Chest

lactic acid has been researched along with Funnel Chest in 4 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Funnel Chest: A developmental anomaly in which the lower sternum is posteriorly dislocated and concavely deformed, resulting in a funnel-shaped thorax.

Research Excerpts

ExcerptRelevanceReference
"The minimally invasive repair of pectus excavatum has become the preferred technique in most centres."1.35Absorbable stabilisation of the bar in minimally invasive repair of pectus excavatum. ( Asquasciati, C; Costanzo, S; Jasonni, V; Romanini, MV; Torre, M; Varela, P, 2008)
"Uncertainty exists as to whether pectus excavatum causes true physiologic impairments to exercise performance as opposed to lack of fitness due to reluctance to exercise."1.32Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. ( Cooper, CB; Fonkalsrud, EW; Malek, MH, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torre, M1
Jasonni, V1
Asquasciati, C1
Costanzo, S1
Romanini, MV1
Varela, P1
Pilegaard, HK1
Licht, PB1
Malek, MH1
Fonkalsrud, EW1
Cooper, CB1
Vleggaar, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aerobic Exercise to Improve Outcomes of Treatment for Methamphetamine Dependence[NCT01103531]135 participants (Actual)Interventional2010-03-31Completed
Phase II Magnetic Alteration of Pectus Excavatum[NCT00466206]Phase 1/Phase 210 participants (Actual)Interventional2007-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Affect on Cardiac Activity

EKG performed prior to implantation, one month post-implantation, and after explanation to evaluate whether magnetic field near the heart adversely affects cardiac activity. Outcome measure describes number of patients who experienced adverse change in EKG. (NCT00466206)
Timeframe: One month post-explantation

Interventionparticipants (Number)
Magnetic Mini-Mover Group0

Damage/Discoloration to Skin

Outcome measure is number of patients who experienced permanent skin damage or discoloration due to external brace wear (NCT00466206)
Timeframe: One-month post-explant

Interventionparticipants (Number)
3MP Treatment Group0

Efficacy: Patient Recommendation of Treatment

"Based on patient response to one-year post-explantation QoL statement: I would recommend this treatment for pectus excavatum (sunken chest) to someone else with pectus excavatum. Ratings: 5-strongly agree; 4-agree; 3-unsure; 2-disagree; 1-strongly disagree" (NCT00466206)
Timeframe: One year post-explanation

InterventionScores on a scale (Mean)
Magnetic Mini-Mover Group4.2

Efficacy: Patient Satisfaction

Based on patient response to one-year post-explantation QoL questionnaire: How satisfied are you with the correction of your chest? Ratings: 5-very satisfied; 4-satisfied; 3-unsure; 2-dissatisfied; 1-very dissatisfied (NCT00466206)
Timeframe: One year post-explant

InterventionScores on a scale (Mean)
3MP Treatment Arm3.7

Patient Compliance

Compliance measured by average number of hours per day external device was worn by patient, as measured by the data sensor and logging device built into external prosthetic (NCT00466206)
Timeframe: 18 months active Rx

Interventionavg hours per day brace worn (Mean)
Treatment Arm16

Other Studies

4 other studies available for lactic acid and Funnel Chest

ArticleYear
Absorbable stabilisation of the bar in minimally invasive repair of pectus excavatum.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2008, Volume: 18, Issue:6

    Topics: Absorbable Implants; Adolescent; Adult; Biocompatible Materials; Child; Funnel Chest; Humans; Lactic

2008
Can absorbable stabilizers be used routinely in the Nuss procedure?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2009, Volume: 35, Issue:4

    Topics: Absorbable Implants; Adolescent; Adult; Child; Female; Funnel Chest; Humans; Lactic Acid; Male; Midd

2009
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Cardiovascular Diseases; Exercise Test; Female; Forced Expiratory Volume; Funnel

2003
Soft-tissue augmentation and the role of poly-L-lactic acid.
    Plastic and reconstructive surgery, 2006, Volume: 118, Issue:3 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Cicatrix; Cosmetic Techniques; Face; Female

2006