lactic acid has been researched along with Fukuhara Disease in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the role of chronic cerebral lactic acidosis in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)." | 9.11 | Cerebral lactic acidosis correlates with neurological impairment in MELAS. ( De Vivo, DC; DiMauro, S; Engelstad, K; Hirano, M; Jhung, S; Kaufmann, P; Mao, X; Mitsis, E; Sano, MC; Shanske, S; Shungu, DC, 2004) |
| "To evaluate the role of chronic cerebral lactic acidosis in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)." | 5.11 | Cerebral lactic acidosis correlates with neurological impairment in MELAS. ( De Vivo, DC; DiMauro, S; Engelstad, K; Hirano, M; Jhung, S; Kaufmann, P; Mao, X; Mitsis, E; Sano, MC; Shanske, S; Shungu, DC, 2004) |
| "Localized brain proton MR spectra were acquired from patients with different mitochondrial encephalomyopathies (myoclonus epilepsy with ragged-red fibers [MERRF], Kearns-Sayre syndrome [KSS], and mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes [MELAS])." | 3.68 | Proton MR spectroscopic characterization of differences in regional brain metabolic abnormalities in mitochondrial encephalomyopathies. ( Andermann, F; Arnold, DL; Karpati, G; Mathews, PM; Silver, K, 1993) |
| "Although there seems to be a gene dosage effect in MERRF, we found no absolute relationship between the relative proportion of mutant genomes in blood and clinical severity." | 1.30 | Gene dosage effect in one family with myoclonic epilepsy and ragged-red fibers (MERRF). ( Arenas, J; Arpa, J; Barreiro, P; Campos, Y; Cruz-Martínez, A; Gutiérrez-Molina, M; Lacasa, T; López-Pajares, R; Martin-Casanueva, MA; Morales, MC; Pérez-Conde, MC; Tatay, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaufmann, P | 1 |
| Shungu, DC | 1 |
| Sano, MC | 1 |
| Jhung, S | 1 |
| Engelstad, K | 1 |
| Mitsis, E | 1 |
| Mao, X | 1 |
| Shanske, S | 1 |
| Hirano, M | 1 |
| DiMauro, S | 1 |
| De Vivo, DC | 1 |
| Mathews, PM | 1 |
| Andermann, F | 1 |
| Silver, K | 1 |
| Karpati, G | 1 |
| Arnold, DL | 1 |
| Arpa, J | 1 |
| Campos, Y | 1 |
| Gutiérrez-Molina, M | 1 |
| Martin-Casanueva, MA | 1 |
| Cruz-Martínez, A | 1 |
| Pérez-Conde, MC | 1 |
| López-Pajares, R | 1 |
| Morales, MC | 1 |
| Tatay, J | 1 |
| Lacasa, T | 1 |
| Barreiro, P | 1 |
| Arenas, J | 1 |
1 trial available for lactic acid and Fukuhara Disease
| Article | Year |
|---|---|
Cerebral lactic acidosis correlates with neurological impairment in MELAS.
Topics: Acidosis, Lactic; Adult; Blood Glucose; Cerebral Ventricles; Chronic Disease; DNA Mutational Analysi | 2004 |
2 other studies available for lactic acid and Fukuhara Disease
| Article | Year |
|---|---|
Proton MR spectroscopic characterization of differences in regional brain metabolic abnormalities in mitochondrial encephalomyopathies.
Topics: Aspartic Acid; Brain; Choline; Creatine; Humans; Kearns-Sayre Syndrome; Lactates; Lactic Acid; Magne | 1993 |
Gene dosage effect in one family with myoclonic epilepsy and ragged-red fibers (MERRF).
Topics: Adult; Age of Onset; Creatine Kinase; Disease Progression; DNA, Mitochondrial; Female; Gene Dosage; | 1997 |