Page last updated: 2024-10-17

lactic acid and Fractures, Bone

lactic acid has been researched along with Fractures, Bone in 40 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Fractures, Bone: Breaks in bones.

Research Excerpts

ExcerptRelevanceReference
"43 cattle with long-bone fractures between July 2016 and Dec 2018."1.72Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures. ( Babkine, M; Constant, C; Desrochers, A; Marchionatti, E; Nichols, S, 2022)
"Low vitamin D levels are associated with stress fractures, but serum vitamin D levels were higher in fracture compared to non-fracture subjects."1.48Elevated Creatine Kinase and Lactic Acid Dehydrogenase and Decreased Osteocalcin and Uncarboxylated Osteocalcin are Associated with Bone Stress Injuries in Young Female Athletes. ( Ishida, H; Ito, E; Kobayashi, T; Matsumoto, H; Matsumoto, M; Miyamoto, K; Miyamoto, T; Nakamura, M; Nishiwaki, Y; Oguma, Y; Otani, T; Sato, Y; Tani, M, 2018)
"Massive hemorrhage was defined as hemorrhage requiring transfusion of≥6 red cell concentrate units within 24h of admission."1.43Scoring system to predict hemorrhage in pelvic ring fracture. ( Hayashi, T; Inoue, T; Kitamura, T; Matsumoto, T; Numoto, K; Ohmori, T; Tada, K; Tamura, R; Tokioka, T, 2016)
"These four children all had seizure activity and abnormal initial neurological examinations and required admission to the PICU."1.33Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury. ( Ball, WS; Care, M; Cecil, KM; Makoroff, KL, 2005)
" The release profile of the microcapsules was designed to mimic a dosing regimen of multiple injections of TAK-778 solution."1.31Enhancement of fracture repair in rats with streptozotocin-induced diabetes by a single injection of biodegradable microcapsules containing a bone formation stimulant, TAK-778. ( Hoshino, T; Makino, H; Muranishi, H; Nagai, H; Notoya, K; Ogawa, Y; Saito, K; Sohda, T, 2000)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.50)18.7374
1990's8 (20.00)18.2507
2000's16 (40.00)29.6817
2010's13 (32.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Constant, C3
Marchionatti, E3
Desrochers, A3
Babkine, M3
Nichols, S3
Sharma, S1
Mudgal, D1
Gupta, V1
Loeffler, J1
Duda, GN1
Sass, FA1
Dienelt, A1
Jiang, W1
Zhang, X2
Lin, B1
Li, W1
Hu, X1
Cheng, J1
Xu, Z1
Chen, Z1
Zhao, Y1
He, T1
Chen, K1
Jiang, L1
Zhang, J1
Wan, H1
Li, R1
Miyamoto, T1
Oguma, Y1
Sato, Y1
Kobayashi, T1
Ito, E1
Tani, M1
Miyamoto, K1
Nishiwaki, Y1
Ishida, H1
Otani, T1
Matsumoto, H1
Matsumoto, M1
Nakamura, M1
Do, WS1
Forte, DM1
Sheldon, RR1
Weiss, JB1
Barron, MR1
Sokol, KK1
Black, GE1
Hegge, SR1
Eckert, MJ1
Martin, MJ1
Zhu, W1
Huang, J1
Lu, W1
Sun, Q1
Peng, L1
Fen, W1
Li, H1
Ou, Y1
Liu, H1
Wang, D1
Zeng, Y1
Tarchala, M1
Harvey, EJ1
Barralet, J1
Ohmori, T1
Matsumoto, T1
Kitamura, T1
Tamura, R1
Tada, K1
Inoue, T1
Hayashi, T1
Numoto, K1
Tokioka, T1
Jayasuriya, AC1
Ebraheim, NA1
Hayakawa, T1
Mochizuki, C1
Hara, H1
Yang, F1
Shen, H1
Wang, S1
Sato, M1
Hao, W1
Pang, L1
Jiang, M1
Lv, R1
Xiong, Z1
Hu, YY1
Hu, YL1
Yuan, WQ1
Wang, LF1
Liu, HF1
Jin, D1
Chen, L1
Liu, L1
Li, C1
Tan, Y1
Zhang, G1
Kono, M1
Mori, R1
Uchio, Y1
Grey, B1
Rodseth, RN1
Muckart, DJ1
Lionelli, GT1
Korentager, RA1
Shafer, BL1
Simonian, PT1
Zhao, J1
Liao, W1
Wang, Y1
Pan, J1
Liu, F1
Huang, C1
Li, J2
Zhu, J1
Li, P1
Xie, G1
Gong, Y1
Gumanenko, EK1
Nemchenko, NS1
Goncharov, AV1
Pashkovskiĭ, EV1
Makoroff, KL1
Cecil, KM1
Care, M1
Ball, WS1
Xiao, R1
Song, Y1
Yang, T1
Huang, F1
Chi, L1
Li, X2
Feng, Q1
Liu, X1
Dong, W1
Cui, F1
Joukainen, A1
Partio, EK2
Waris, P1
Joukainen, J1
Kröger, H1
Törmälä, P1
Rokkanen, P1
Zou, J1
Zhu, G1
Qi, X1
Pu, Y1
Alexander, H1
Langrana, N1
Massengill, JB1
Weiss, AB1
Athanasiou, KA1
Niederauer, GG1
Agrawal, CM1
Mainil-Varlet, P1
Cordey, J1
Landolt, M1
Gogolewski, S1
Gosain, AK1
Song, L1
Corrao, MA1
Pintar, FA1
Böstman, OM2
Illi, OE1
Feldmann, CP1
Pihlajamäki, HK1
George, K1
Becker, D1
Seligson, D1
Hoshino, T1
Muranishi, H1
Saito, K1
Notoya, K1
Makino, H1
Nagai, H1
Sohda, T1
Ogawa, Y1
Spector, JA1
Mehrara, BJ1
Greenwald, JA1
Saadeh, PB1
Steinbrech, DS1
Bouletreau, PJ1
Smith, LP1
Longaker, MT1
Mosier-Laclair, S1
Pike, H1
Pomeroy, G1
Thordarson, DB1
Samuelson, M1
Shepherd, LE1
Merkle, PF1
Lee, J1
Voutilainen, NH1
Hess, MW1
Toivonen, TS1
Krogerus, LA1
Pätiälä, HV1
Kumta, SM1
Spinner, R1
Leung, PC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Establishment for Prediction Model of Intraoperative Blood Transfusion for Patients With Pelvic Fracture in China: A Multicenter Observational Study[NCT03855644]2,000 participants (Anticipated)Observational [Patient Registry]2019-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for lactic acid and Fractures, Bone

ArticleYear
The Metabolic Microenvironment Steers Bone Tissue Regeneration.
    Trends in endocrinology and metabolism: TEM, 2018, Volume: 29, Issue:2

    Topics: Animals; Bone Regeneration; Fractures, Bone; Humans; Inflammation; Lactic Acid; Mesenchymal Stem Cel

2018
Biomaterial-Stabilized Soft Tissue Healing for Healing of Critical-Sized Bone Defects: the Masquelet Technique.
    Advanced healthcare materials, 2016, Volume: 5, Issue:6

    Topics: Animals; Biocompatible Materials; Fractures, Bone; Lactic Acid; Polyglycolic Acid; Polylactic Acid-P

2016
Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers.
    Biomaterials, 1996, Volume: 17, Issue:2

    Topics: Animals; Biocompatible Materials; Cell Division; Fractures, Bone; Humans; Lactic Acid; Ligaments; Or

1996
Intraosseous bioabsorbable poly-L-lactic acid screw presenting as a late foreign-body reaction: a case report.
    Foot & ankle international, 2001, Volume: 22, Issue:3

    Topics: Abscess; Absorbable Implants; Adolescent; Bone Screws; Female; Foot Injuries; Foreign-Body Reaction;

2001

Trials

5 trials available for lactic acid and Fractures, Bone

ArticleYear
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2017, 08-15, Volume: 31, Issue:8

    Topics: Animals; Fracture Fixation, Internal; Fracture Healing; Fractures, Bone; Humans; Knee Injuries; Knee

2017
[A prospective randomized trial of poly-DL-lactic acid absorbable and metallic screws for treatment of syndesmotic disruptions].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:10

    Topics: Absorbable Implants; Adult; Ankle Injuries; Bone Screws; Female; Fibula; Fractures, Bone; Humans; La

2010
Bioabsorbable screw fixation for the treatment of ankle fractures.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2007, Volume: 12, Issue:1

    Topics: Absorbable Implants; Adolescent; Adult; Aged; Ankle Injuries; Bone Screws; Equipment Design; Female;

2007
Bioabsorbable versus stainless steel screw fixation of the syndesmosis in pronation-lateral rotation ankle fractures: a prospective randomized trial.
    Foot & ankle international, 2001, Volume: 22, Issue:4

    Topics: Absorbable Implants; Adult; Ankle Injuries; Bone Screws; Female; Follow-Up Studies; Fracture Fixatio

2001
Absorbable intramedullary implants for hand fractures. Animal experiments and clinical trial.
    The Journal of bone and joint surgery. British volume, 1992, Volume: 74, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Biodegradation, Environmental; Bone Wires; Female; Femur; Follow-U

1992

Other Studies

31 other studies available for lactic acid and Fractures, Bone

ArticleYear
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Admission lactate concentration has predictive value for death or severe complications within 30 days after admission in cattle with long-bone fractures.
    Journal of the American Veterinary Medical Association, 2022, 11-24, Volume: 261, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Fractures, Bone; Lactic Acid; Prognosis; Prospective Studies; ROC

2022
Advancement in biological and mechanical behavior of 3D printed poly lactic acid bone plates using polydopamine coating: Innovation for healthcare.
    Journal of the mechanical behavior of biomedical materials, 2023, Volume: 143

    Topics: Apatites; Bone Plates; Delivery of Health Care; Fractures, Bone; Humans; Lactic Acid; Polyesters; Pr

2023
Elevated Creatine Kinase and Lactic Acid Dehydrogenase and Decreased Osteocalcin and Uncarboxylated Osteocalcin are Associated with Bone Stress Injuries in Young Female Athletes.
    Scientific reports, 2018, 12-21, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Athletes; Athletic Injuries; Biomarkers; Carbon Dioxide; Case-Control Studies; Cr

2018
Minimally invasive preperitoneal balloon tamponade and abdominal aortic junctional tourniquet versus open packing for pelvic fracture-associated hemorrhage: Not all extrinsic compression is equal.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:4

    Topics: Animals; Aorta, Abdominal; Balloon Occlusion; Bandages; Blood Loss, Surgical; Fractures, Bone; Hemat

2019
Performance test of Nano-HA/PLLA composites for interface fixation.
    Artificial cells, nanomedicine, and biotechnology, 2014, Volume: 42, Issue:5

    Topics: Biocompatible Materials; Bone and Bones; Durapatite; Fracture Fixation, Internal; Fractures, Bone; H

2014
Scoring system to predict hemorrhage in pelvic ring fracture.
    Orthopaedics & traumatology, surgery & research : OTSR, 2016, Volume: 102, Issue:8

    Topics: Abbreviated Injury Scale; Aged; Area Under Curve; Blood Transfusion; Case-Control Studies; Contrast

2016
Evaluation of bone matrix and demineralized bone matrix incorporated PLGA matrices for bone repair.
    Journal of materials science. Materials in medicine, 2009, Volume: 20, Issue:8

    Topics: Animals; Bone Demineralization Technique; Bone Matrix; Bone Regeneration; Bone Substitutes; Cell Adh

2009
In vivo evaluation of composites of PLGA and apatite with two different levels of crystallinity.
    Journal of materials science. Materials in medicine, 2010, Volume: 21, Issue:1

    Topics: Absorbable Implants; Animals; Bone Substitutes; Crystallization; Durapatite; Female; Fracture Healin

2010
Skeletal repair in rabbits using a novel biomimetic composite based on adipose-derived stem cells encapsulated in collagen I gel with PLGA-beta-TCP scaffold.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:2

    Topics: Adipocytes; Animals; Biocompatible Materials; Biomimetics; Calcium Phosphates; Collagen Type I; Elas

2010
A new growth factor controlled drug release system to promote healing of bone fractures: nanospheres of recombinant human bone morphogenetic-2 and polylactic acid.
    Journal of nanoscience and nanotechnology, 2011, Volume: 11, Issue:4

    Topics: Bone Morphogenetic Protein 2; Cell Line; Delayed-Action Preparations; Fracture Healing; Fractures, B

2011
Bone screws have advantages in repair of experimental osteochondral fragments.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:7

    Topics: Animals; Biomechanical Phenomena; Bone Regeneration; Bone Screws; Cartilage, Articular; Cattle; Dise

2012
Early fracture stabilisation in the presence of subclinical hypoperfusion.
    Injury, 2013, Volume: 44, Issue:2

    Topics: Adult; Arterial Pressure; Cell Hypoxia; Female; Femoral Fractures; Fracture Fixation, Internal; Frac

2013
Biomechanical failure of metacarpal fracture resorbable plate fixation.
    Annals of plastic surgery, 2002, Volume: 49, Issue:2

    Topics: Absorbable Implants; Adult; Bone Plates; Equipment Failure; Fracture Fixation, Internal; Fractures,

2002
Broken poly-L-lactic acid interference screw after ligament reconstruction.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2002, Volume: 18, Issue:7

    Topics: Accidents, Traffic; Achilles Tendon; Adolescent; Adult; Ankle Injuries; Anterior Cruciate Ligament;

2002
Preparation and degradation characteristic study of bone repair composite of DL-polylactic acid/hydroxyapatite/decalcifying bone matrix.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2002, Volume: 5, Issue:6

    Topics: Biocompatible Materials; Biopolymers; Bone and Bones; Bone Density; Bone Matrix; Bone Substitutes; D

2002
[A comparative study on two different absorbable intramedullary nails in treating metacarpal and phalanx fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2004, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Bone Nails; Chitosan; Female; Follow-Up Studies; Fracture Fixation, Intramedullar

2004
[Pathogenetical features of the acute period of traumatic disease. Traumatic shock as a special manifestation of the acute period].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:6

    Topics: Abdominal Injuries; Acidosis; Acute Disease; Coma, Post-Head Injury; Disseminated Intravascular Coag

2004
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
    Pediatric radiology, 2005, Volume: 35, Issue:7

    Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe

2005
[A preliminary clinical study on absorbable screws].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2005, Volume: 22, Issue:5

    Topics: Absorbable Implants; Adolescent; Adult; Ankle Injuries; Bone Screws; Child; Female; Fracture Fixatio

2005
Collagen-based implants reinforced by chitin fibres in a goat shank bone defect model.
    Biomaterials, 2006, Volume: 27, Issue:9

    Topics: Animals; Bone and Bones; Bone Density; Bone Regeneration; Chitin; Collagen; Compressive Strength; Du

2006
[In vivo degradation and tissue compatibility of poly-L-lactide/beta-tricalcium phosphate composite rods for internal fixation of bone fractures].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2007, Volume: 24, Issue:1

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Calcium Phosphates; Fractures, Bone; Internal

2007
Development of new methods for phalangeal fracture fixation.
    Journal of biomechanics, 1981, Volume: 14, Issue:6

    Topics: Animals; Biomechanical Phenomena; Carbon; Carbon Fiber; Finger Injuries; Fracture Fixation, Intramed

1981
The use of a resorbable augmentation device to secure plating of osteoporotic bones. An in vitro study.
    International orthopaedics, 1997, Volume: 21, Issue:4

    Topics: Bone Cements; Bone Plates; Fracture Fixation, Internal; Fractures, Bone; Humans; In Vitro Techniques

1997
Biomechanical evaluation of titanium, biodegradable plate and screw, and cyanoacrylate glue fixation systems in craniofacial surgery.
    Plastic and reconstructive surgery, 1998, Volume: 101, Issue:3

    Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Biomechanical Phenomena; Bone Plate

1998
Osteoarthritis of the ankle after foreign-body reaction to absorbable pins and screws: a three- to nine-year follow-up study.
    The Journal of bone and joint surgery. British volume, 1998, Volume: 80, Issue:2

    Topics: Absorption; Adult; Ankle Joint; Biocompatible Materials; Bone Nails; Bone Screws; Chi-Square Distrib

1998
Stimulation of fracture healing by local application of humoral factors integrated in biodegradable implants.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1998, Volume: 8, Issue:4

    Topics: Absorbable Implants; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Plates

1998
Late foreign-body reaction to an intraosseous bioabsorbable polylactic acid screw. A case report.
    The Journal of bone and joint surgery. American volume, 1998, Volume: 80, Issue:12

    Topics: Absorbable Implants; Adult; Ankle Injuries; Bone Screws; Female; Foreign-Body Reaction; Fractures, B

1998
Absorbable fasteners for the fixation of ankle fractures.
    The Journal of the Kentucky Medical Association, 1999, Volume: 97, Issue:3

    Topics: Absorbable Implants; Adult; Ankle Injuries; Female; Fractures, Bone; Humans; Internal Fixators; Lact

1999
Enhancement of fracture repair in rats with streptozotocin-induced diabetes by a single injection of biodegradable microcapsules containing a bone formation stimulant, TAK-778.
    Journal of biomedical materials research, 2000, Sep-05, Volume: 51, Issue:3

    Topics: Animals; Benzothiepins; Biocompatible Materials; Biodegradation, Environmental; Capsules; Diabetes M

2000
Osteoblast expression of vascular endothelial growth factor is modulated by the extracellular microenvironment.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:1

    Topics: Acidosis, Lactic; Animals; Animals, Newborn; Cells, Cultured; Endothelial Growth Factors; Extracellu

2001
A long-term clinical study on dislocated ankle fractures fixed with self-reinforced polylevolactide (SR-PLLA) implants.
    Journal of long-term effects of medical implants, 2002, Volume: 12, Issue:1

    Topics: Absorbable Implants; Adult; Ankle Injuries; Female; Foreign-Body Reaction; Fracture Fixation; Fractu

2002