lactic acid has been researched along with Foreign-Body Granuloma in 29 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Excerpt | Relevance | Reference |
---|---|---|
" OBJECTIVE To review the use of injectable PLLA, specifically regarding optimal injection technique that can reduce adverse events (AEs) and enhance out comes." | 2.44 | Minimizing adverse events associated with poly-L-lactic acid injection. ( Narins, RS, 2008) |
" Recent evidence shows that local/regional/systemic delayed adverse effects may appear with its use." | 1.35 | Late-onset immune-mediated adverse effects after poly-L-lactic acid injection in non-HIV patients: clinical findings and long-term follow-up. ( Alijotas-Reig, J; Garcia-Gimenez, V; Vilardell-Tarres, M, 2009) |
"For the glabellar region, severe partly vascular adverse events have been reported after treatment with injectable fillers." | 1.35 | The spectrum of adverse reactions after treatment with injectable fillers in the glabellar region: results from the Injectable Filler Safety Study. ( Bachmann, F; Erdmann, R; Hartmann, V; Rzany, B; Wiest, L, 2009) |
"Polylactic acid (PLA) is an agent that is injected with the aim of enhancing the host's own collagen deposition." | 1.34 | Adverse reactions to polylactic acid injections in the periorbital area. ( Apikian, M; Goodman, GJ; Roberts, S, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (6.90) | 18.2507 |
2000's | 22 (75.86) | 29.6817 |
2010's | 5 (17.24) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ledon, JA | 1 |
Savas, JA | 1 |
Yang, S | 1 |
Franca, K | 1 |
Camacho, I | 1 |
Nouri, K | 1 |
Fuller, ML | 1 |
Bradley, EA | 1 |
Narins, RS | 1 |
Reszko, AE | 1 |
Sadick, NS | 1 |
Magro, CM | 1 |
Farber, J | 1 |
Beer, K | 1 |
Bentkover, SH | 1 |
Curcio, NM | 1 |
Parish, LC | 1 |
Azizzadeh, B | 2 |
Alijotas-Reig, J | 1 |
Garcia-Gimenez, V | 1 |
Vilardell-Tarres, M | 1 |
Bachmann, F | 1 |
Erdmann, R | 1 |
Hartmann, V | 1 |
Wiest, L | 1 |
Rzany, B | 1 |
Luginbuehl, V | 1 |
Ruffieux, K | 1 |
Hess, C | 1 |
Reichardt, D | 1 |
von Rechenberg, B | 1 |
Nuss, K | 1 |
Avery, C | 1 |
Clifford, N | 1 |
Schuller-Petrović, S | 1 |
Pavlović, MD | 1 |
Schuller, SS | 1 |
Schuller-Lukić, B | 1 |
Neuhold, N | 1 |
Lombardi, T | 1 |
Samson, J | 1 |
Plantier, F | 1 |
Husson, C | 1 |
Küffer, R | 1 |
Dijkema, SJ | 1 |
van der Lei, B | 1 |
Kibbelaar, RE | 1 |
Oppel, T | 1 |
Schaller, M | 1 |
Flaig, M | 1 |
Korting, HC | 1 |
Poveda, R | 1 |
Bagán, JV | 1 |
Murillo, J | 1 |
Jiménez, Y | 1 |
Andre, P | 1 |
Lowe, NJ | 1 |
Parc, A | 1 |
Clerici, TH | 1 |
Zimmermann, U | 1 |
Bauer, U | 1 |
Vleggaar, D | 1 |
Lam, SM | 1 |
Graivier, M | 1 |
Wildemore, JK | 1 |
Jones, DH | 1 |
Wolfram, D | 1 |
Tzankov, A | 1 |
Piza-Katzer, H | 1 |
Spoliti, M | 1 |
Apikian, M | 1 |
Roberts, S | 1 |
Goodman, GJ | 1 |
Dionyssopoulos, A | 1 |
Nikolis, A | 1 |
Patsatsi, A | 1 |
Sotiriadis, D | 1 |
Vieu, C | 1 |
Arnault, JP | 1 |
Petitpain, N | 1 |
Cuny, JF | 1 |
Barbaud, A | 1 |
Plenat, F | 1 |
Schmutz, JL | 1 |
Goldan, O | 1 |
Garbov-Nardini, G | 1 |
Regev, E | 1 |
Orenstein, A | 1 |
Winkler, E | 1 |
Gould, L | 1 |
Trope, G | 1 |
Cheng, YL | 1 |
Heathcote, JG | 1 |
Sheardown, H | 1 |
Rootman, D | 1 |
Liu, GS | 1 |
Menon, IA | 1 |
Suuronen, R | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Split-face Study of Changing in Skin Physiology and Clinical Appearance After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces[NCT02312154] | Phase 4 | 25 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"We measured a elasticity by a reviscometer device (Courage & Khazaka, Cologne, Germany).~The range of elasticity was 0 (most elastic possible as) ~400 AU(Arbitrary Unit) (inelastic as possible)" (NCT02312154)
Timeframe: 12 weeks
Intervention | AU (arbitrary unit) (Mean) |
---|---|
Treated Side (Restylane Vital) | 242.33 |
Untreated Side | 271.15 |
"We measured an erythema index by a mexameter device (Courage & Khazaka, Cologne, Germany).~The range of erythema index is 0~999 AU(Arbitrary Unit). The range of erythema index was 0 (as non-erythematous as possible) ~999 AU (most erythematous possible)" (NCT02312154)
Timeframe: 12 weeks
Intervention | AU (arbitrary unit) (Mean) |
---|---|
Treated Side (Restylane Vital) | 253.66 |
Untreated Side | 243.53 |
The therapeutic outcome was assessed by investigator using the Global Aesthetic Improvement Scale (GAIS), which rates outcome on the following 5-point scale: 3, very much improved; 2, much improved; 1, improved; 0, no change; and -1, worse. (NCT02312154)
Timeframe: 12 weeks
Intervention | scores on a scale (Mean) |
---|---|
Treated Side (Restylane Vital) | 1.38 |
Untreated Side | 0 |
The therapeutic outcome was assessed by patient self-assessment using the Global Aesthetic Improvement Scale (GAIS), which rates outcome on the following 5-point scale: 3, very much improved; 2, much improved; 1, improved; 0, no change; and -1, worse (NCT02312154)
Timeframe: 12 weeks
Intervention | scores on a scale (Mean) |
---|---|
Treated Side (Restylane Vital) | 1.33 |
Untreated Side | 0 |
"We measured a hydration level by a corneometer device (Courage & Khazaka, Cologne, Germany).~The range of hydration level was 0 (as dry as possible) ~120 AU (Arbitrary Unit)(most moist possible)" (NCT02312154)
Timeframe: 12 weeks
Intervention | AU (arbitrary unit) (Mean) |
---|---|
Treated Side (Restylane Vital) | 53.19 |
Untreated Side | 46.75 |
"We measured a melanin index by a mexameter device (Courage & Khazaka, Cologne, Germany).~The range of melanin index was 0 (as bright as possible) ~999 AU (Arbitrary Unit) (most dark possible)." (NCT02312154)
Timeframe: 12 weeks
Intervention | AU (arbitrary unit) (Mean) |
---|---|
Treated Side (Restylane Vital) | 147.25 |
Untreated Side | 149.00 |
4 reviews available for lactic acid and Foreign-Body Granuloma
Article | Year |
---|---|
Inflammatory nodules following soft tissue filler use: a review of causative agents, pathology and treatment options.
Topics: Acrylic Resins; Adipose Tissue; Biocompatible Materials; Collagen; Dermatologic Agents; Durapatite; | 2013 |
Minimizing adverse events associated with poly-L-lactic acid injection.
Topics: Cellulose; Cosmetic Techniques; Drug Compounding; Face; Female; Granuloma, Foreign-Body; HIV-Associa | 2008 |
Adverse reactions to dermal fillers: a review of European experiences.
Topics: Acrylates; Acrylic Resins; Biocompatible Materials; Cellulose; Collagen; Cosmetic Techniques; Drug E | 2005 |
Biodegradable fracture-fixation devices in maxillofacial surgery.
Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Bone Plates; Bone Screws; Fracture | 1993 |
25 other studies available for lactic acid and Foreign-Body Granuloma
Article | Year |
---|---|
Facial Ulcers and Restrictive Strabismus From Delayed Periorbital Granuloma After Poly-L-Lactic Acid Injection.
Topics: Cosmetic Techniques; Face; Female; Granuloma, Foreign-Body; Humans; Injections, Intradermal; Lactic | 2015 |
Late-onset subcutaneous nodules after poly-L-lactic acid injection.
Topics: Cellulose; Collagen; Cosmetic Techniques; Female; Giant Cells, Foreign-Body; Granuloma, Foreign-Body | 2009 |
Clinicopathologic correlation of delayed-onset periorbital poly-L-lactic acid nodules.
Topics: Cosmetic Techniques; Face; Female; Granuloma, Foreign-Body; Humans; Lactic Acid; Middle Aged; Polyes | 2009 |
The biology of facial fillers.
Topics: Animals; Biocompatible Materials; Biofilms; Cattle; Chondrogenesis; Collagen; Cosmetic Techniques; D | 2009 |
Injectable fillers: an American perspective.
Topics: Acrylic Resins; Animals; Biocompatible Materials; Cattle; Collagen; Cosmetic Techniques; Dermatologi | 2009 |
Late-onset infections and granuloma formation after facial polylactic acid (new-fill) injections in women who are heavy smokers.
Topics: Bacterial Infections; Cellulose; Cosmetic Techniques; Female; Granuloma, Foreign-Body; Humans; Injec | 2009 |
Late-onset immune-mediated adverse effects after poly-L-lactic acid injection in non-HIV patients: clinical findings and long-term follow-up.
Topics: Adult; Aged; Biocompatible Materials; Cohort Studies; Cosmetic Techniques; Edema; Face; Female; Foll | 2009 |
The spectrum of adverse reactions after treatment with injectable fillers in the glabellar region: results from the Injectable Filler Safety Study.
Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Cicatrix; Dermatologic Agents; Drug Combina | 2009 |
Controlled release of tetracycline from biodegradable beta-tricalcium phosphate composites.
Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Biocompatible Materials; Calcium Phosphates; Ce | 2010 |
Foreign body granulomatous reaction of the temporal region following dermal filler administration.
Topics: Cosmetic Techniques; Female; Granuloma, Foreign-Body; Humans; Injections, Intradermal; Lactic Acid; | 2010 |
Early granulomatous foreign body reactions to a novel alginate dermal filler: the system's failure?
Topics: Adult; Alginates; Cellulose; Cosmetic Techniques; Dermatologic Agents; Esthetics; Female; Follow-Up | 2013 |
Orofacial granulomas after injection of cosmetic fillers. Histopathologic and clinical study of 11 cases.
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Cellulose; Collagen; Cosmetic Techniques; Face; Female; G | 2004 |
New-fill injections may induce late-onset foreign body granulomatous reaction.
Topics: Adult; Cellulose; Cheek; Cosmetic Techniques; Female; Granuloma, Foreign-Body; Humans; Lactic Acid; | 2005 |
[Facial foreign body granulomas after dermal injection of a polylactate-based implant for wrinkles].
Topics: Facial Dermatoses; Female; Granuloma, Foreign-Body; Humans; Lactic Acid; Middle Aged; Polyesters; Po | 2003 |
Granulomatous facial reaction to injected cosmetic fillers--a presentation of five cases.
Topics: Aged; Animals; Anti-Inflammatory Agents; Cattle; Collagen; Cosmetic Techniques; Face; Female; Granul | 2006 |
Response to "New-fill injections may induce late-onset foreign body granulomatous reaction".
Topics: Cellulose; Cosmetic Techniques; Granuloma, Foreign-Body; Humans; Lactic Acid; Mannitol; Polymers; Pr | 2006 |
Injectable poly-L-lactic acid (Sculptra): technical considerations in soft-tissue contouring.
Topics: Adult; Aged; Biocompatible Materials; Cellulose; Cheek; Cosmetic Techniques; Face; Female; Freeze Dr | 2006 |
Persistent granulomatous inflammatory response induced by injectable poly-L-lactic acid for HIV lipoatrophy.
Topics: Biocompatible Materials; Diagnosis, Differential; Face; Granuloma, Foreign-Body; HIV-Associated Lipo | 2006 |
Surgery for foreign body reactions due to injectable fillers.
Topics: Acrylates; Adult; Biocompatible Materials; Cellulose; Collagen; Cosmetic Techniques; Facial Dermatos | 2006 |
Glenoid osteolysis after arthroscopic labrum repair with a bioabsorbable suture anchor.
Topics: Absorbable Implants; Adult; Arthroscopy; Athletic Injuries; Female; Follow-Up Studies; Granuloma, Fo | 2007 |
Adverse reactions to polylactic acid injections in the periorbital area.
Topics: Cellulose; Cosmetic Techniques; Dermatologic Agents; Face; Female; Granuloma, Foreign-Body; Humans; | 2007 |
Granulomas of the lips: a rare complication after injection of polylactic acid for aesthetic augmentation.
Topics: Cosmetic Techniques; Female; Granuloma, Foreign-Body; Humans; Lactic Acid; Lip Diseases; Middle Aged | 2007 |
[Granuloma at the injection site of leuprorelin acetate: foreign body reaction to polylactic acid].
Topics: Aged; Buttocks; Granuloma, Foreign-Body; Humans; Injections, Intramuscular; Lactic Acid; Leuprolide; | 2007 |
Late-onset infections and granuloma formation after facial polylactic acid (New-Fill) injections in women who are heavy smokers.
Topics: Abscess; Drainage; Face; Female; Granuloma, Foreign-Body; Humans; Injections, Intradermal; Lactic Ac | 2008 |
Fifty:fifty poly (DL glycolic acid-lactic acid) copolymer as a drug delivery system for 5-fluorouracil: a histopathological evaluation.
Topics: Animals; Biocompatible Materials; Conjunctiva; Drug Delivery Systems; Fibrosis; Fluorouracil; Glycol | 1994 |