lactic acid has been researched along with Fetal Growth Restriction in 44 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on 2 women with organic acidemias, one with classical maple syrup urine disease and another with mild propionic acidemia in which protein restricted diets and carnitine supplementation were successfully employed to manage pregnancies." | 7.68 | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. ( Barness, LA; Davidson, SR; Harding, CO; Van Calcar, SC; Wolff, JA, 1992) |
| " Taurine may have been released by the tissues as a protective mechanism against hypoxia-induced inflammation, or in an attempt to maintain osmotic balance." | 3.74 | Taurine as a marker for foetal wellbeing? ( de Boo, HA; Harding, JE, 2007) |
| " Of the 24 fetuses with normal heart rates and abnormal velocimetry, 4 (17 percent) had moderate lactic acidosis, 1 (4 percent) had a low pH value, and 3 (12 percent) had hypoxia." | 3.68 | Diagnostic value of blood sampling in fetuses with growth retardation. ( Battaglia, FC; Bozzetti, P; Buscaglia, M; Cetin, I; Ferrazzi, E; Lanfranchi, A; Marconi, AM; Pardi, G, 1993) |
| "We report on 2 women with organic acidemias, one with classical maple syrup urine disease and another with mild propionic acidemia in which protein restricted diets and carnitine supplementation were successfully employed to manage pregnancies." | 3.68 | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. ( Barness, LA; Davidson, SR; Harding, CO; Van Calcar, SC; Wolff, JA, 1992) |
| "During placental insufficiency-induced intrauterine growth restriction (PI-IUGR), uteroplacental weight-specific oxygen consumption rates are maintained, yet fetal glucose and amino acid supply is decreased and fetal lactate concentrations are increased." | 1.91 | Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency. ( Brown, LD; Julian, CG; Kyllo, HM; Lorca, RA; Moore, LG; Rozance, PJ; Wang, D; Wesolowski, SR; Wilkening, RB, 2023) |
| "Considering SGA being a proxy for fetal growth restriction, and acidemia a proxy for hypoxia, it is concluded that growth-restricted fetuses have an intact ability to develop lacticemia during hypoxia." | 1.48 | The small-for-gestational-age fetus has an intact ability to develop lacticemia when exposed to hypoxia: a retrospective comparative register study. ( Åkerman, F; Källén, K; Mokarami, P; Olofsson, P, 2018) |
| "While utero-placental insufficiency is associated with adverse outcomes for both mother and fetus, many of the maternal-fetal adaptations during pregnancy in models of fetal compromise remain unclear." | 1.38 | Circulating and utero-placental adaptations to chronic placental ischemia in the rat. ( Banek, CT; Bauer, AJ; Chasson, S; Gilbert, JS; Gingery, A, 2012) |
| "In addition, intrauterine growth retardation (IUGR) increases the susceptibility of offspring to high-fat (HF) diet-induced metabolic syndrome." | 1.38 | Intrauterine growth retardation increases the susceptibility of pigs to high-fat diet-induced mitochondrial dysfunction in skeletal muscle. ( Chen, D; He, J; Huang, Z; Liu, J; Mao, X; Yao, Y; Yu, B; Zheng, P, 2012) |
| "Nutritional interventions for intrauterine growth restriction (IUGR) have raised concerns for fetal toxicity, the mechanisms of which are unknown." | 1.35 | Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. ( Barry, JS; Brown, LD; Hay, WW; Limesand, SW; Rozance, PJ, 2009) |
| "Severe fetal growth restriction (FGR) is often associated with hypoxia." | 1.34 | Development and mechanisms of fetal hypoxia in severe fetal growth restriction. ( Battaglia, FC; de Vrijer, B; Galan, HL; Meschia, G; Regnault, TR; Wilkening, RB, 2007) |
| "Newborns with intrauterine growth retardation show lower preprandial values of glucose and ketone bodies than newborns with appropriate weight, but higher levels of lactate and pyruvate; nevertheless the lactate/pyruvate and beta-hydroxybutyrate/acetoacetate ratios are normal." | 1.32 | Redox status in very-low birth-weight newborns. ( Bossoli, S; Dani, C; Filippi, L; Giani, T; Messeri, A; Pezzati, M; Rubaltelli, FF; Tronchin, M, 2004) |
| "Many fetuses suffering from intrauterine growth restriction (IUGR) are hypoglycaemic." | 1.32 | Glucose metabolism in the human preterm and term placenta of IUGR fetuses. ( Jansson, T; Magnusson, AL; Powell, T; Wennergren, M, 2004) |
| "Severe hypoxemia induces similar alterations of renal excretion in newborn piglets." | 1.31 | Effect of severe normocapnic hypoxia on renal function in growth-restricted newborn piglets. ( Bauer, R; Walter, B; Zwiener, U, 2000) |
| "Intrauterine growth retardation was induced in newborn dogs after 3 days of maternal nutritional deprivation (birth weight 251 +/- 7 versus 227 +/- 7 g, p less than 0." | 1.27 | Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs. ( Kliegman, RM, 1988) |
| "We examined the possibility that in preeclampsia complicated by fetal growth retardation, placental energy state is low either because of impaired glycolysis or because of ischemia resulting from reduced maternal placental blood flow." | 1.27 | Placental glycolysis and energy metabolism in preeclampsia. ( Bloxam, DL; Bullen, BE; Lao, TT; Walters, BN, 1987) |
| "In 14 pregnancies complicated by intrauterine growth retardation, the umbilical cord was sampled before delivery under ultrasonic guidance for rapid fetal karyotyping." | 1.27 | Cord sampling for the evaluation of oxygenation and acid-base balance in growth-retarded human fetuses. ( Battaglia, FC; Bozzetti, P; Buscaglia, M; Cetin, I; Ferrazzi, E; Makowski, EL; Marconi, AM; Pardi, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.36) | 18.7374 |
| 1990's | 9 (20.45) | 18.2507 |
| 2000's | 14 (31.82) | 29.6817 |
| 2010's | 13 (29.55) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, AK | 1 |
| Wang, D | 2 |
| Goldstrohm, DA | 1 |
| Brown, LD | 3 |
| Rozance, PJ | 4 |
| Limesand, SW | 3 |
| Wesolowski, SR | 2 |
| Kyllo, HM | 1 |
| Lorca, RA | 1 |
| Julian, CG | 1 |
| Moore, LG | 1 |
| Wilkening, RB | 3 |
| Zhang, H | 1 |
| Chen, Y | 1 |
| Li, Y | 1 |
| Wang, T | 1 |
| Åkerman, F | 1 |
| Mokarami, P | 1 |
| Källén, K | 1 |
| Olofsson, P | 1 |
| Parisi, S | 1 |
| Monzeglio, C | 1 |
| Attini, R | 1 |
| Biolcati, M | 1 |
| Masturzo, B | 1 |
| Mensa, M | 1 |
| Mischinelli, M | 1 |
| Pilloni, E | 1 |
| Todros, T | 1 |
| Metges, CC | 1 |
| Görs, S | 1 |
| Lang, IS | 1 |
| Hammon, HM | 1 |
| Brüssow, KP | 1 |
| Weitzel, JM | 1 |
| Nürnberg, G | 1 |
| Rehfeldt, C | 1 |
| Otten, W | 1 |
| Brutsaert, TD | 1 |
| Tamvada, KH | 1 |
| Kiyamu, M | 1 |
| White, DD | 1 |
| Gage, TB | 1 |
| Corvino, SB | 1 |
| Netto, AO | 1 |
| Sinzato, YK | 1 |
| Campos, KE | 1 |
| Calderon, IM | 1 |
| Rudge, MV | 1 |
| Volpato, GT | 1 |
| Zambrano, E | 1 |
| Damasceno, DC | 1 |
| Andescavage, N | 1 |
| Limperopoulos, C | 1 |
| Evangelou, I | 1 |
| Murnick, J | 1 |
| du Plessis, A | 1 |
| Barry, JS | 1 |
| Hay, WW | 3 |
| Charles-Edwards, GD | 1 |
| Jan, W | 1 |
| To, M | 1 |
| Maxwell, D | 1 |
| Keevil, SF | 1 |
| Robinson, R | 1 |
| Cetin, I | 4 |
| Barberis, B | 1 |
| Brusati, V | 1 |
| Brighina, E | 1 |
| Mandia, L | 1 |
| Arighi, A | 1 |
| Radaelli, T | 1 |
| Biondetti, P | 1 |
| Bresolin, N | 1 |
| Pardi, G | 5 |
| Rango, M | 1 |
| Højbjerre, L | 1 |
| Alibegovic, AC | 1 |
| Sonne, MP | 1 |
| Dela, F | 1 |
| Vaag, A | 1 |
| Bruun, JM | 1 |
| Stallknecht, B | 1 |
| Gilbert, JS | 1 |
| Bauer, AJ | 1 |
| Gingery, A | 1 |
| Banek, CT | 1 |
| Chasson, S | 1 |
| Liu, J | 1 |
| Chen, D | 1 |
| Yao, Y | 1 |
| Yu, B | 1 |
| Mao, X | 1 |
| He, J | 1 |
| Huang, Z | 1 |
| Zheng, P | 1 |
| Holzmann, M | 1 |
| Cnattingius, S | 1 |
| Nordström, L | 1 |
| Torrance, HL | 1 |
| Pistorius, L | 1 |
| Voorbij, HA | 1 |
| Visser, GH | 1 |
| Selak, MA | 1 |
| Storey, BT | 1 |
| Peterside, I | 1 |
| Simmons, RA | 1 |
| Filippi, L | 1 |
| Messeri, A | 1 |
| Dani, C | 1 |
| Pezzati, M | 1 |
| Tronchin, M | 1 |
| Giani, T | 1 |
| Bossoli, S | 1 |
| Rubaltelli, FF | 1 |
| Magnusson, AL | 1 |
| Powell, T | 1 |
| Wennergren, M | 1 |
| Jansson, T | 2 |
| de Vrijer, B | 2 |
| Regnault, TR | 2 |
| Meschia, G | 2 |
| Battaglia, FC | 6 |
| Marconi, AM | 4 |
| Paolini, CL | 1 |
| Zerbe, G | 1 |
| Settle, P | 1 |
| Sibley, CP | 1 |
| Doughty, IM | 1 |
| Johnston, T | 1 |
| Glazier, JD | 1 |
| Powell, TL | 1 |
| D'Souza, SW | 1 |
| Galan, HL | 1 |
| de Boo, HA | 1 |
| Harding, JE | 1 |
| Wallace, JM | 1 |
| Milne, JS | 1 |
| Aitken, RP | 1 |
| Smith, D | 1 |
| Moxon-Lester, L | 1 |
| Sinclair, K | 1 |
| Burke, C | 1 |
| Cowin, GJ | 1 |
| Rose, SE | 1 |
| Colditz, P | 1 |
| Azpurua, H | 1 |
| Alvarado, A | 1 |
| Mayobre, F | 1 |
| Salom, T | 1 |
| Copel, JA | 1 |
| Guevara-Zuloaga, F | 1 |
| Robinson, JS | 1 |
| Jones, CT | 1 |
| Kingston, EJ | 1 |
| Leth, H | 1 |
| Toft, PB | 1 |
| Pryds, O | 1 |
| Peitersen, B | 1 |
| Lou, HC | 1 |
| Henriksen, O | 1 |
| Ferrazzi, E | 4 |
| Bellotti, M | 1 |
| Marconi, A | 1 |
| Flisi, L | 1 |
| Barbera, A | 1 |
| Steiner, H | 1 |
| Staudach, A | 1 |
| Spitzer, D | 1 |
| Schaffer, KH | 1 |
| Gregg, A | 1 |
| Weiner, CP | 1 |
| Lanfranchi, A | 1 |
| Bozzetti, P | 2 |
| Buscaglia, M | 2 |
| Boyle, DW | 1 |
| Lecklitner, S | 1 |
| Liechty, EA | 1 |
| Lin, CH | 2 |
| Gelardi, NL | 2 |
| Cha, CJ | 2 |
| Oh, W | 2 |
| Bauer, R | 1 |
| Walter, B | 1 |
| Zwiener, U | 1 |
| Van Calcar, SC | 1 |
| Harding, CO | 1 |
| Davidson, SR | 1 |
| Barness, LA | 1 |
| Wolff, JA | 1 |
| Ferrari, MM | 1 |
| Fowden, AL | 1 |
| Hughes, P | 1 |
| Comline, RS | 1 |
| Kliegman, RM | 1 |
| Bloxam, DL | 1 |
| Bullen, BE | 1 |
| Walters, BN | 1 |
| Lao, TT | 1 |
| Makowski, EL | 1 |
1 trial available for lactic acid and Fetal Growth Restriction
| Article | Year |
|---|---|
Lactate production as a response to intrapartum hypoxia in the growth-restricted fetus.
Topics: Acidosis, Lactic; Adult; Birth Weight; Female; Fetal Blood; Fetal Growth Retardation; Fetal Hypoxia; | 2012 |
43 other studies available for lactic acid and Fetal Growth Restriction
| Article | Year |
|---|---|
Tissue-specific responses that constrain glucose oxidation and increase lactate production with the severity of hypoxemia in fetal sheep.
Topics: Adipose Tissue; Animals; Disease Models, Animal; Female; Fetal Growth Retardation; Fetal Hypoxia; Fe | 2022 |
Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency.
Topics: Amino Acids; AMP-Activated Protein Kinases; Animals; Female; Fetal Growth Retardation; Fetus; Glucos | 2023 |
Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets.
Topics: Amine Oxidase (Copper-Containing); AMP-Activated Protein Kinases; Animals; Dietary Supplements; DNA, | 2020 |
The small-for-gestational-age fetus has an intact ability to develop lacticemia when exposed to hypoxia: a retrospective comparative register study.
Topics: Analysis of Variance; Biomarkers; Blood Glucose; Case-Control Studies; Female; Fetal Blood; Fetal Gr | 2018 |
Evidence of lower oxygen reserves during labour in the growth restricted human foetus: a retrospective study.
Topics: Birth Weight; Cardiotocography; Female; Fetal Blood; Fetal Distress; Fetal Growth Retardation; Heart | 2017 |
Low and high dietary protein:carbohydrate ratios during pregnancy affect materno-fetal glucose metabolism in pigs.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Blood Glucose; Brain; Diet; Diet, Carbohydrate | 2014 |
Response to an aerobic training intervention in young adults depends on ponderal index at birth.
Topics: Adult; Birth Weight; Body Composition; Exercise; Female; Fetal Development; Fetal Growth Retardation | 2012 |
Intrauterine Growth Restricted Rats Exercised at Pregnancy: Maternal-Fetal Repercussions.
Topics: Acidosis, Lactic; Animals; Biomarkers; Birth Weight; Blood Glucose; Diabetes Mellitus, Experimental; | 2015 |
Pregnancy outcomes in two growth restricted fetuses with in utero cerebral lactate.
Topics: Brain; Fatal Outcome; Female; Fetal Growth Retardation; Fetus; Humans; Infant, Newborn; Lactic Acid; | 2015 |
Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction.
Topics: Acidosis; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Disease Models, Animal; Down-Regulati | 2009 |
Non-invasive detection and quantification of human foetal brain lactate in utero by magnetic resonance spectroscopy.
Topics: Adult; Biomarkers; Brain; Brain Chemistry; Female; Fetal Growth Retardation; Fetal Hypoxia; Fetus; H | 2010 |
Lactate detection in the brain of growth-restricted fetuses with magnetic resonance spectroscopy.
Topics: Brain; Brain Chemistry; Feasibility Studies; Fetal Growth Retardation; Humans; Lactic Acid; Magnetic | 2011 |
Increased lipolysis but diminished gene expression of lipases in subcutaneous adipose tissue of healthy young males with intrauterine growth retardation.
Topics: Adult; Bed Rest; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; | 2011 |
Circulating and utero-placental adaptations to chronic placental ischemia in the rat.
Topics: Adaptation, Physiological; Animals; Female; Fetal Development; Fetal Growth Retardation; Fetus; Insu | 2012 |
Intrauterine growth retardation increases the susceptibility of pigs to high-fat diet-induced mitochondrial dysfunction in skeletal muscle.
Topics: Animals; Blood Glucose; Diet, High-Fat; DNA, Mitochondrial; Eating; Female; Fetal Growth Retardation | 2012 |
Lactate to creatinine ratio in amniotic fluid: a pilot study.
Topics: Acidosis, Lactic; Amniotic Fluid; Biomarkers; Cesarean Section; Creatinine; Female; Fetal Blood; Fet | 2013 |
Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats.
Topics: Aconitate Hydratase; Adenosine Triphosphate; Animals; Blood Glucose; Blotting, Western; Citrate (si) | 2003 |
Redox status in very-low birth-weight newborns.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Female; Fetal Growth Retardation; Gluconeogenesis; Glucose; Hu | 2004 |
Glucose metabolism in the human preterm and term placenta of IUGR fetuses.
Topics: Adult; Biological Transport; Chorionic Villi; Female; Fetal Growth Retardation; Gestational Age; Glu | 2004 |
Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction.
Topics: Animals; Biological Transport; Blood Glucose; Body Temperature; Cycloleucine; Ethanol; Female; Fetal | 2004 |
Lactacidemia in intrauterine growth restricted (IUGR) pregnancies: relationship to clinical severity, oxygenation and placental weight.
Topics: Female; Fetal Growth Retardation; Fetal Weight; Gestational Age; Humans; Lactic Acid; Organ Size; Ox | 2006 |
Placental lactate transporter activity and expression in intrauterine growth restriction.
Topics: Amniotic Fluid; Blotting, Western; Carbon Radioisotopes; Female; Fetal Growth Retardation; Gestation | 2006 |
Development and mechanisms of fetal hypoxia in severe fetal growth restriction.
Topics: Animals; Blood Glucose; Body Temperature; Disease Models, Animal; Female; Fetal Blood; Fetal Growth | 2007 |
Taurine as a marker for foetal wellbeing?
Topics: Amino Acids; Animals; Biomarkers; Disease Models, Animal; Female; Fetal Death; Fetal Development; Fe | 2007 |
Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep.
Topics: Adiposity; Animals; Body Weight; Female; Fetal Growth Retardation; Fetus; Glucose; Glucose Clamp Tec | 2007 |
Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction.
Topics: Animals; Blood Glucose; Cyclic AMP Response Element-Binding Protein; Female; Fetal Growth Retardatio | 2007 |
Increased cerebral lactate during hypoxia may be neuroprotective in newborn piglets with intrauterine growth restriction.
Topics: Animals; Animals, Newborn; Apoptosis; Birth Weight; Brain; Brain Chemistry; Cell Count; Diffusion Ma | 2007 |
Metabolic assessment of the brain using proton magnetic resonance spectroscopy in a growth-restricted human fetus: case report.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Child, Preschool; Choline; Female; Fetal Growth Retard | 2008 |
Studies on experimental growth retardation in sheep. The effects of maternal hypoxaemia.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Endometrium; Female; Fetal Growth Retardation; | 1983 |
Brain lactate in preterm and growth-retarded neonates.
Topics: Brain; Corpus Striatum; Fetal Growth Retardation; Humans; Infant; Infant, Newborn; Infant, Premature | 1995 |
Peak velocity of the outflow tract of the aorta: correlations with acid base status and oxygenation of the growth-retarded fetus.
Topics: Aorta; Blood Flow Velocity; Carbon Dioxide; Ductus Arteriosus; Female; Fetal Growth Retardation; Ges | 1995 |
Growth deficient fetuses with absent or reversed umbilical artery end-diastolic flow are metabolically compromised.
Topics: Carbon Dioxide; Cesarean Section; Cordocentesis; Diastole; Female; Fetal Growth Retardation; Gestati | 1995 |
Diagnostic value of blood sampling in fetuses with growth retardation.
Topics: Acidosis; Amino Acids; Cordocentesis; Delivery, Obstetric; Female; Fetal Diseases; Fetal Growth Reta | 1993 |
Effect of prolonged uterine blood flow reduction on fetal growth in sheep.
Topics: Animals; Biological Availability; Blood Glucose; Embryonic and Fetal Development; Female; Fetal Bloo | 1996 |
Cerebral metabolic response to hypoglycemia in severe intrauterine growth-retarded rat pups.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Brain; Female; Fetal Growth Retardation; Glucose; Hy | 1998 |
Cerebral metabolic response to hypoglycemia in severe intrauterine growth-retarded rat pups.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Fetal Growth Retardation; Glucose; Hypoglycemia; Lac | 1998 |
Effect of severe normocapnic hypoxia on renal function in growth-restricted newborn piglets.
Topics: Acidosis; Animals; Animals, Newborn; Blood Gas Analysis; Blood Glucose; Blood Pressure; Carbon Dioxi | 2000 |
Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia.
Topics: Adult; Amino Acids; Carbon-Carbon Ligases; Carnitine; Citrates; Citric Acid; Female; Fetal Growth Re | 1992 |
Lactate metabolism in normal and growth-retarded human fetuses.
Topics: Female; Fetal Blood; Fetal Growth Retardation; Fetal Hypoxia; Fetus; Humans; Lactates; Lactic Acid; | 1990 |
The effects of insulin on the growth rate of the sheep fetus during late gestation.
Topics: Animals; Blood Glucose; Embryonic and Fetal Development; Female; Fetal Growth Retardation; Gestation | 1989 |
Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs.
Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Female; Fetal Growth Retardation; Glycogen | 1988 |
Placental glycolysis and energy metabolism in preeclampsia.
Topics: Adenine Nucleotides; Energy Metabolism; Female; Fetal Growth Retardation; Glycolysis; Humans; Lactat | 1987 |
Cord sampling for the evaluation of oxygenation and acid-base balance in growth-retarded human fetuses.
Topics: Acid-Base Equilibrium; Female; Fetal Blood; Fetal Growth Retardation; Fetal Monitoring; Heart Rate, | 1987 |