lactic acid has been researched along with Fatigue Syndrome, Chronic in 18 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies in chronic fatigue syndrome (CFS) have reported reductions in maximal oxygen uptake (VO(2max)), yet often the testing procedures have not followed accepted guidelines, and gender data have been pooled." | 2.70 | Maximal oxygen uptake and lactate metabolism are normal in chronic fatigue syndrome. ( Buckley, JD; Burnet, RB; Nemeth, PM; Sargent, C; Scroop, GC, 2002) |
| " The fatigue task altered the dose-response relationship to intramuscular acidic saline injections." | 1.34 | Muscle fatigue increases the probability of developing hyperalgesia in mice. ( Lisi, TL; Moore, SA; Sluka, KA; Yokoyama, T, 2007) |
| "Muscle histometry in patients with chronic fatigue syndrome generally did not show the changes expected as a result of inactivity." | 1.30 | Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome. ( Archard, LC; Barrett, MC; Fletcher, R; Lane, RJ; Moss, J; Woodrow, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, XS | 1 |
| Ma, W | 1 |
| Xiong, LJ | 1 |
| Zhai, CT | 1 |
| Li, W | 1 |
| Tian, YF | 1 |
| Natelson, BH | 2 |
| Mao, X | 4 |
| Stegner, AJ | 1 |
| Lange, G | 1 |
| Vu, D | 1 |
| Blate, M | 1 |
| Kang, G | 1 |
| Soto, E | 1 |
| Kapusuz, T | 1 |
| Shungu, DC | 4 |
| Mueller, C | 1 |
| Lin, JC | 1 |
| Sheriff, S | 1 |
| Maudsley, AA | 1 |
| Younger, JW | 1 |
| Torrell, H | 1 |
| Alonso, Y | 1 |
| Garrabou, G | 1 |
| Mulet, D | 1 |
| Catalán, M | 1 |
| Valiente-Pallejà, A | 1 |
| Carreño-Gago, L | 1 |
| García-Arumí, E | 1 |
| Montaña, E | 1 |
| Vilella, E | 1 |
| Martorell, L | 1 |
| Mathew, SJ | 3 |
| Keegan, KA | 1 |
| Levine, SM | 2 |
| Smith, EL | 1 |
| Heier, LA | 1 |
| Otcheretko, V | 1 |
| Coplan, JD | 1 |
| Kindlon, T | 1 |
| Murrough, JW | 2 |
| Collins, KA | 1 |
| Kelly, C | 1 |
| Andrade, G | 1 |
| Nestadt, P | 1 |
| Cao, Y | 1 |
| Hu, Y | 1 |
| Liu, P | 1 |
| Zhao, HX | 1 |
| Zhou, XJ | 1 |
| Wei, YM | 1 |
| Weiduschat, N | 1 |
| Pillemer, S | 1 |
| Dyke, JP | 1 |
| Medow, MS | 1 |
| Stewart, JM | 1 |
| Jones, NL | 1 |
| Heigenhauser, GJ | 1 |
| Dalakas, MC | 1 |
| Lane, RJ | 3 |
| Soteriou, BA | 1 |
| Zhang, H | 1 |
| Archard, LC | 2 |
| Wallman, KE | 1 |
| Morton, AR | 1 |
| Goodman, C | 1 |
| Grove, R | 1 |
| Yokoyama, T | 1 |
| Lisi, TL | 1 |
| Moore, SA | 1 |
| Sluka, KA | 1 |
| Wassif, WS | 1 |
| Sherman, D | 1 |
| Salisbury, JR | 1 |
| Peters, TJ | 1 |
| Barrett, MC | 2 |
| Woodrow, D | 1 |
| Moss, J | 1 |
| Fletcher, R | 1 |
| Taylor, DJ | 1 |
| Kemp, GJ | 1 |
| Lodi, R | 1 |
| Sargent, C | 1 |
| Scroop, GC | 1 |
| Nemeth, PM | 1 |
| Burnet, RB | 1 |
| Buckley, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of Exercise Response in Chronic Fatigue Syndrome / Myalgic Encephalomyelitis.[NCT03675087] | 22 participants (Anticipated) | Observational | 2019-02-27 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for lactic acid and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Use of dynamic tests of muscle function and histomorphometry of quadriceps muscle biopsies in the investigation of patients with chronic alcohol misuse and chronic fatigue syndrome.
Topics: Adult; Alcoholism; Ammonia; AMP Deaminase; Analysis of Variance; Biopsy, Needle; Creatine Kinase; Di | 1994 |
Maximal oxygen uptake and lactate metabolism are normal in chronic fatigue syndrome.
Topics: Adult; Anaerobic Threshold; Exercise Test; Exercise Tolerance; Fatigue Syndrome, Chronic; Female; He | 2002 |
16 other studies available for lactic acid and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
[Effect of herbal cake-separated moxibustion on behavioral stress reactions and blood lactic acid level and muscular AMPK/PGC-1α signaling in rats with chronic fatigue syndrome].
Topics: AMP-Activated Protein Kinases; Animals; beta-Endorphin; Fatigue Syndrome, Chronic; Lactic Acid; Moxi | 2022 |
Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity.
Topics: Adult; Analysis of Variance; Brain; Cerebrovascular Circulation; Cohort Studies; Fatigue Syndrome, C | 2017 |
Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Fatigue; Fatigue Syndrome, Chronic; Female; Humans; | 2020 |
Mitochondrial dysfunction in a family with psychosis and chronic fatigue syndrome.
Topics: Adult; Aged; Cell Respiration; DNA, Mitochondrial; Enzymes; Family Health; Fatigue Syndrome, Chronic | 2017 |
Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T (1)H MRS imaging study.
Topics: Adolescent; Adult; Anxiety Disorders; Cerebral Ventricles; Demography; Fatigue Syndrome, Chronic; Fe | 2009 |
Stratification using biological factors should be performed in more CFS studies.
Topics: Biomarkers; Cognitive Behavioral Therapy; Diagnosis, Differential; Energy Metabolism; Exercise; Fati | 2010 |
Increased ventricular lactate in chronic fatigue syndrome measured by 1H MRS imaging at 3.0 T. II: comparison with major depressive disorder.
Topics: Adult; Cerebral Ventricles; Depressive Disorder, Major; Fatigue Syndrome, Chronic; Female; gamma-Ami | 2010 |
Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running.
Topics: Animals; Blood Urea Nitrogen; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Fat | 2012 |
Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology.
Topics: Adolescent; Adult; Cerebral Cortex; Cerebral Ventricles; Cerebrovascular Circulation; Demography; Fa | 2012 |
VO2max and lactate production are not normal in all patients with chronic fatigue.
Topics: Adult; Anaerobic Threshold; Fatigue Syndrome, Chronic; Humans; Lactic Acid; Male; Muscle, Skeletal; | 2002 |
Enteroviruses in chronic fatigue syndrome: "now you see them, now you don't".
Topics: DNA, Bacterial; DNA, Viral; Enterovirus; Exercise; Fatigue Syndrome, Chronic; Humans; Inflammation; | 2003 |
Enterovirus related metabolic myopathy: a postviral fatigue syndrome.
Topics: Adult; DNA, Viral; Enterovirus; Enterovirus B, Human; Exercise; Exercise Test; Fatigue Syndrome, Chr | 2003 |
Physiological responses during a submaximal cycle test in chronic fatigue syndrome.
Topics: Adult; Case-Control Studies; Exercise Test; Exercise Tolerance; Fatigue Syndrome, Chronic; Fear; Fem | 2004 |
Muscle fatigue increases the probability of developing hyperalgesia in mice.
Topics: Animals; Carbon Dioxide; Cumulative Trauma Disorders; Disease Models, Animal; Dose-Response Relation | 2007 |
Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome.
Topics: Adult; Anaerobic Threshold; Biopsy, Needle; Exercise; Exercise Test; Fatigue Syndrome, Chronic; Fema | 1998 |
Heterogeneity in chronic fatigue syndrome: evidence from magnetic resonance spectroscopy of muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Biopsy; Fatigue Syndrome, Chronic; Female; For | 1998 |