Page last updated: 2024-10-17

lactic acid and Facial Dermatoses

lactic acid has been researched along with Facial Dermatoses in 24 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Facial Dermatoses: Skin diseases involving the FACE.

Research Excerpts

ExcerptRelevanceReference
" We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin."9.34Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020)
"Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities."9.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"Salicylic acid (SA) peel is a well-established peeling agent for acne."6.84Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017)
" We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin."5.34Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020)
"Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities."5.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"The Jessner's-trichloroacetic acid (TCA) peel is a procedure developed by Monheit to produce a safe, effective medium-depth chemical peel for the treatment of photoaged skin, actinic keratoses, and superficial acne scars."4.79The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel. ( Monheit, GD, 1995)
"75% and lactic acid 15% on improving the periorbital hyperpigmentation."3.79Chemical peeling with trichloroacetic acid and lactic acid for infraorbital dark circles. ( Alexandru, A; Gregoriou, S; Katsambas, A; Kontochristopoulos, G; Salavastru, C; Teodor, A; Vavouli, C, 2013)
"Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne."3.73Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients. ( Huh, CH; Lee, SH; Park, KC; Youn, SW, 2006)
"Salicylic acid (SA) peel is a well-established peeling agent for acne."2.84Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017)
" The incidence of adverse effect was maximum with GA peel followed by lactic peel and vitamin C."2.82Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study. ( Dayal, S; Jain, VK; Khetri, S; Sahu, P, 2016)
" Visible AK were counted, random skin biopsies performed, adverse effects monitored, and patients questioned about preference and perception of efficacy."2.68A comparison of the efficacy and safety of Jessner's solution and 35% trichloroacetic acid vs 5% fluorouracil in the treatment of widespread facial actinic keratoses. ( Cockerell, CJ; Cox, SE; Cruz, PD; Freeman, RG; Lawrence, N, 1995)
" Despite their obvious benefits, a wide range of possible complications such as immediate, late, delayed, temporary, or irreversible adverse effects have to be respected."2.50Adverse effects of fillers and their histopathology. ( Haneke, E, 2014)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's5 (20.83)18.2507
2000's11 (45.83)29.6817
2010's6 (25.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
How, KN1
Lim, PY1
Wan Ahmad Kammal, WSL1
Shamsudin, N1
Vavouli, C1
Katsambas, A1
Gregoriou, S1
Teodor, A1
Salavastru, C1
Alexandru, A1
Kontochristopoulos, G1
Metivier, D1
Montravers, F1
Balogova, S1
Talbot, JN1
Haneke, E1
Dayal, S2
Sahu, P2
Jain, VK2
Khetri, S1
Amrani, A1
Truchuelo, M1
Cerdá, P1
Fernández, LF1
Sadick, NS1
Valantin, MA1
Aubron-Olivier, C1
Ghosn, J1
Laglenne, E1
Pauchard, M1
Schoen, H1
Bousquet, R1
Katz, P1
Costagliola, D1
Katlama, C1
Boix, V1
Marriott, M1
Whittle, E1
Basketter, DA1
Perry, CM1
Lafaurie, M1
Dolivo, M1
Porcher, R1
Rudant, J1
Madelaine, I1
Molina, JM1
Guaraldi, G1
Orlando, G1
De Fazio, D1
De Lorenzi, I1
Rottino, A1
De Santis, G1
Pedone, A1
Spaggiari, A1
Baccarani, A1
Borghi, V1
Esposito, R1
Oppel, T1
Schaller, M1
Flaig, M1
Korting, HC1
Lee, SH1
Huh, CH1
Park, KC1
Youn, SW1
Wolfram, D1
Tzankov, A1
Piza-Katzer, H1
Hamilton, DG1
Gauthier, N1
Robertson, BF1
Monheit, GD1
Lawrence, N3
Cox, SE3
Cockerell, CJ2
Freeman, RG1
Cruz, PD1
Brody, HJ2
Witheiler, DD1
Cruz, C1
Freemen, RG1
Kim, SW1
Moon, SE1
Kim, JA1
Eun, HC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Structural Fat Grafting for Craniofacial Trauma: Repeat Fat Grafting Injection-5 Subject Cohort[NCT01822301]5 participants (Actual)Interventional2013-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Facial Volume Score

the facial volume and appearance grading scale evaluates each aesthetic region in the face based on both physical examination and 3D photography by the clinician. scale ranges from 1-3 where a score of 1 indicates an obvious contour defect; 2 shows a noticeable improvement in contour but not sufficient to impart a normal appearance; 3 represents a normal appearance and/or close approximation with a normal uninjured contralateral structure. (NCT01822301)
Timeframe: assessed at baseline (pre-op), days 7-21 post-op, 3 months post-op, and 9 months post-op

Interventionunits on a scale (Mean)
Facial Volume Score at Baseline1.8
Facial Volume Score at 7-21 Day PO2.2
Facial Volume Score at 3 Month PO2.2
Facial Volume Score at 9 Months PO2.6

Serial Computed Tomography Imaging

serial computed tomography images were collected to evaluate the volume of the defect (NCT01822301)
Timeframe: assessed at 7-21 days, 3 months and 9 months post op.

Interventionvolume, mL (Mean)
CT Imaging at 7-21 Days PO15
CT Imaging at 3 Months PO10.3
CT Imaging at 9 Months PO12.4

Reviews

5 reviews available for lactic acid and Facial Dermatoses

ArticleYear
Adverse effects of fillers and their histopathology.
    Facial plastic surgery : FPS, 2014, Volume: 30, Issue:6

    Topics: Acrylic Resins; Adipose Tissue; Alginates; Biocompatible Materials; Collagen; Cosmetic Techniques; D

2014
Chemical Peeling: A Useful Tool in the Office.
    Actas dermo-sifiliograficas, 2017, Volume: 108, Issue:4

    Topics: Acids; Animals; Chemexfoliation; Collagen Type I; Drug Combinations; Elastin; Epidermis; Ethanol; Fa

2017
The impact of cosmetic interventions on quality of life.
    Dermatology online journal, 2008, Aug-15, Volume: 14, Issue:8

    Topics: Acrylic Resins; Biocompatible Materials; Botulinum Toxins, Type A; Clinical Trials as Topic; Cosmeti

2008
Poly-L-lactic acid.
    American journal of clinical dermatology, 2004, Volume: 5, Issue:5

    Topics: Adipose Tissue; Biocompatible Materials; Delayed-Action Preparations; Dose-Response Relationship, Dr

2004
The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel.
    Dermatologic clinics, 1995, Volume: 13, Issue:2

    Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Drug Combinations; Ethanol; Face; Facial Dermatoses; Human

1995

Trials

8 trials available for lactic acid and Facial Dermatoses

ArticleYear
Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.
    International journal of dermatology, 2020, Volume: 59, Issue:7

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Facial Derma

2020
Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study.
    Journal of cosmetic dermatology, 2016, Volume: 15, Issue:4

    Topics: Administration, Cutaneous; Adult; Antioxidants; Ascorbic Acid; Chemexfoliation; Eye; Facial Dermatos

2016
Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.
    Journal of cosmetic dermatology, 2017, Volume: 16, Issue:1

    Topics: Acne Vulgaris; Adolescent; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Female; H

2017
Treatment of facial lipoatrophy with intradermal injections of polylactic acid in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2005, Apr-01, Volume: 38, Issue:4

    Topics: Adult; Antiretroviral Therapy, Highly Active; Facial Dermatoses; Female; Follow-Up Studies; HIV Infe

2005
Comparison of three different interventions for the correction of HIV-associated facial lipoatrophy: a prospective study.
    Antiviral therapy, 2005, Volume: 10, Issue:6

    Topics: Acrylic Resins; Adipose Tissue; Adult; Facial Dermatoses; Female; HIV Infections; HIV-Associated Lip

2005
A comparison of the efficacy and safety of Jessner's solution and 35% trichloroacetic acid vs 5% fluorouracil in the treatment of widespread facial actinic keratoses.
    Archives of dermatology, 1995, Volume: 131, Issue:2

    Topics: Drug Combinations; Ethanol; Facial Dermatoses; Fluorouracil; Follow-Up Studies; Humans; Keratosis; L

1995
Treatment of melasma with Jessner's solution versus glycolic acid: a comparison of clinical efficacy and evaluation of the predictive ability of Wood's light examination.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:4

    Topics: Chemexfoliation; Colorimetry; Drug Combinations; Ethanol; Facial Dermatoses; Female; Glycolates; Hum

1997
Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

1999

Other Studies

11 other studies available for lactic acid and Facial Dermatoses

ArticleYear
Chemical peeling with trichloroacetic acid and lactic acid for infraorbital dark circles.
    Journal of cosmetic dermatology, 2013, Volume: 12, Issue:3

    Topics: Adult; Aged; Caustics; Chemexfoliation; Esthetics; Eye; Facial Dermatoses; Female; Humans; Hyperpigm

2013
18F-FDG PET/CT uptake due to poly-L-lactic acid facial injections.
    Nuklearmedizin. Nuclear medicine, 2013, Dec-13, Volume: 52, Issue:6

    Topics: Aged; Diagnosis, Differential; Facial Dermatoses; False Positive Reactions; Fluorodeoxyglucose F18;

2013
Polylactic acid implants (New-Fill) to correct facial lipoatrophy in HIV-infected patients: results of the open-label study VEGA.
    AIDS (London, England), 2003, Nov-21, Volume: 17, Issue:17

    Topics: Adipose Tissue; Adult; Antiretroviral Therapy, Highly Active; Biocompatible Materials; Drug Implants

2003
Polylactic acid implants. A new smile for lipoatrophic faces?
    AIDS (London, England), 2003, Nov-21, Volume: 17, Issue:17

    Topics: Antiretroviral Therapy, Highly Active; Biocompatible Materials; Drug Implants; Facial Dermatoses; HI

2003
Facial variations in sensory responses.
    Contact dermatitis, 2003, Volume: 49, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Dermatitis, Allergic Contact; Facial Dermatoses; Female;

2003
[Facial foreign body granulomas after dermal injection of a polylactate-based implant for wrinkles].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2003, Volume: 1, Issue:3

    Topics: Facial Dermatoses; Female; Granuloma, Foreign-Body; Humans; Lactic Acid; Middle Aged; Polyesters; Po

2003
Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

2006
Surgery for foreign body reactions due to injectable fillers.
    Dermatology (Basel, Switzerland), 2006, Volume: 213, Issue:4

    Topics: Acrylates; Adult; Biocompatible Materials; Cellulose; Collagen; Cosmetic Techniques; Facial Dermatos

2006
Late-onset, recurrent facial nodules associated with injection of poly-L-lactic acid.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008, Volume: 34, Issue:1

    Topics: Anti-Inflammatory Agents; Cellulose; Cosmetic Techniques; Dermatologic Agents; Face; Facial Dermatos

2008
Long-term efficacy and safety of Jessner's solution and 35% trichloroacetic acid vs 5% fluorouracil in the treatment of widespread facial actinic keratoses.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1997, Volume: 23, Issue:3

    Topics: Administration, Topical; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fluorouraci

1997
Variations and comparisons in medium-depth chemical peeling.
    The Journal of dermatologic surgery and oncology, 1989, Volume: 15, Issue:9

    Topics: Administration, Topical; Adult; Carbon Dioxide; Chemexfoliation; Drug Combinations; Epidermis; Ethan

1989