lactic acid has been researched along with Eye Diseases in 16 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the antiviral effect of ganciclovir released from biodegradable polymer microspheres in rabbit eyes inoculated with human cytomegalovirus (HCMV)." | 7.69 | Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus. ( Herrero-Vanrell, R; Refojo, MF; Veloso, AA; Zhu, Q, 1997) |
| "To test the antiviral effect of ganciclovir released from biodegradable polymer microspheres in rabbit eyes inoculated with human cytomegalovirus (HCMV)." | 3.69 | Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus. ( Herrero-Vanrell, R; Refojo, MF; Veloso, AA; Zhu, Q, 1997) |
| "The plugs are effective for treating vitreoretinal diseases such as proliferative vitreoretinopathy." | 2.41 | Biodegradable scleral plugs for vitreoretinal drug delivery. ( Kimura, H; Ogura, Y; Tabata, Y; Yasukawa, T, 2001) |
| " The aim of this study to assess the bioavailability and safety of SFAs as drug solvents for the topical ocular application of Cyclosporin A (CsA)." | 1.40 | Semifluorinated alkanes as a liquid drug carrier system for topical ocular drug delivery. ( Dutescu, RM; Merkel, OM; Panfil, C; Schrage, N, 2014) |
| " Based on the area-under-the-curve (AUC), the bioavailability of DEX in the experimental group was significantly higher than that in the control group administrated with regular DEX." | 1.39 | Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases. ( Bu, S; Jiang, L; Xie, X; Yang, C; Zeng, Q; Zhang, L; Zheng, Y; Zhu, D, 2013) |
| " The resultant microparticles were also formulated in two dosage forms, an aqueous suspension and a dry tablet, to test the effect of formulation on the retention capacity of microparticles on the preocular space of rabbits in vivo." | 1.35 | Mucoadhesive microdiscs engineered for ophthalmic drug delivery: effect of particle geometry and formulation on preocular residence time. ( Choy, YB; Edelhauser, HF; McCarey, BE; Park, JH; Prausnitz, MR, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katara, R | 1 |
| Sachdeva, S | 1 |
| Majumdar, DK | 1 |
| Gonzalez-Pizarro, R | 1 |
| Silva-Abreu, M | 1 |
| Calpena, AC | 1 |
| Egea, MA | 1 |
| Espina, M | 1 |
| García, ML | 1 |
| Yang, C | 1 |
| Jiang, L | 1 |
| Bu, S | 1 |
| Zhang, L | 1 |
| Xie, X | 1 |
| Zeng, Q | 1 |
| Zhu, D | 1 |
| Zheng, Y | 1 |
| Dutescu, RM | 1 |
| Panfil, C | 1 |
| Merkel, OM | 1 |
| Schrage, N | 1 |
| Yang, X | 1 |
| Shah, SJ | 1 |
| Wang, Z | 1 |
| Agrahari, V | 1 |
| Pal, D | 1 |
| Mitra, AK | 1 |
| Kim, J | 1 |
| Schlesinger, EB | 1 |
| Desai, TA | 1 |
| Sah, AK | 1 |
| Suresh, PK | 1 |
| Verma, VK | 1 |
| Choy, YB | 1 |
| Park, JH | 1 |
| McCarey, BE | 1 |
| Edelhauser, HF | 1 |
| Prausnitz, MR | 1 |
| Funk, MJ | 1 |
| Belinson, SE | 1 |
| Pimenta, JM | 1 |
| Morsheimer, M | 1 |
| Gibbons, DC | 1 |
| Ozkaya, YG | 1 |
| Ağar, A | 1 |
| Hacioğlu, G | 1 |
| Yargiçoğlu, P | 1 |
| Bertram, JP | 1 |
| Saluja, SS | 1 |
| McKain, J | 1 |
| Lavik, EB | 1 |
| Giordano, GG | 1 |
| Refojo, MF | 3 |
| Arroyo, MH | 1 |
| Veloso, AA | 1 |
| Zhu, Q | 1 |
| Herrero-Vanrell, R | 2 |
| Yasukawa, T | 1 |
| Kimura, H | 1 |
| Tabata, Y | 1 |
| Ogura, Y | 1 |
| Petty, RK | 1 |
| Harding, AE | 1 |
| Morgan-Hughes, JA | 1 |
3 reviews available for lactic acid and Eye Diseases
| Article | Year |
|---|---|
Nanostructured materials for ocular delivery: nanodesign for enhanced bioadhesion, transepithelial permeability and sustained delivery.
Topics: Cell Membrane Permeability; Drug Carriers; Eye Diseases; Humans; Lactic Acid; Nanopores; Nanostructu | 2015 |
Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy.
Topics: Anemia; Animals; Anti-HIV Agents; Blood Cell Count; Developmental Disabilities; DNA, Mitochondrial; | 2007 |
Biodegradable scleral plugs for vitreoretinal drug delivery.
Topics: Animals; Biodegradation, Environmental; Cytomegalovirus Retinitis; Drug Delivery Systems; Eye Diseas | 2001 |
13 other studies available for lactic acid and Eye Diseases
| Article | Year |
|---|---|
Enhancement of ocular efficacy of aceclofenac using biodegradable PLGA nanoparticles: formulation and characterization.
Topics: Administration, Ophthalmic; Animals; Arachidonic Acid; Calorimetry, Differential Scanning; Chemistry | 2017 |
Development of fluorometholone-loaded PLGA nanoparticles for treatment of inflammatory disorders of anterior and posterior segments of the eye.
Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Biological Availability; Chickens; Ch | 2018 |
Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Diffusion; Eye Diseases; Intravitreal Injections; | 2013 |
Semifluorinated alkanes as a liquid drug carrier system for topical ocular drug delivery.
Topics: Administration, Topical; Alkanes; Animals; Castor Oil; Cornea; Cyclosporine; Drug Carriers; Eye; Eye | 2014 |
Nanoparticle-based topical ophthalmic formulation for sustained release of stereoisomeric dipeptide prodrugs of ganciclovir.
Topics: Administration, Ophthalmic; Delayed-Action Preparations; Dipeptides; Drug Delivery Systems; Emulsion | 2016 |
PLGA nanoparticles for ocular delivery of loteprednol etabonate: a corneal penetration study.
Topics: Administration, Ophthalmic; Animals; Cornea; Drug Delivery Systems; Eye Diseases; Goats; Lactic Acid | 2017 |
Mucoadhesive microdiscs engineered for ophthalmic drug delivery: effect of particle geometry and formulation on preocular residence time.
Topics: Adhesiveness; Administration, Topical; Animals; Biocompatible Materials; Conjunctiva; Drug Carriers; | 2008 |
Exercise improves visual deficits tested by visual evoked potentials in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Evoked Potentials, Visual; Eye | 2007 |
Sustained delivery of timolol maleate from poly(lactic-co-glycolic acid)/poly(lactic acid) microspheres for over 3 months.
Topics: Delayed-Action Preparations; Eye Diseases; Humans; Lactic Acid; Microspheres; Polyesters; Polyglycol | 2009 |
Sustained delivery of retinoic acid from microspheres of biodegradable polymer in PVR.
Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Delayed-Action Preparations; Diseas | 1993 |
Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus.
Topics: Animals; Antigens, Viral; Biocompatible Materials; Biodegradation, Environmental; Cytomegalovirus; C | 1997 |
Biodegradable microspheres for vitreoretinal drug delivery.
Topics: Animals; Biodegradation, Environmental; Drug Delivery Systems; Eye Diseases; Humans; Lactic Acid; Mi | 2001 |
The clinical features of mitochondrial myopathy.
Topics: Adolescent; Adult; Aged; Central Nervous System Diseases; Creatine Kinase; Eye Diseases; Female; Hum | 1986 |