Page last updated: 2024-10-17

lactic acid and Erythrocytosis

lactic acid has been researched along with Erythrocytosis in 8 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Chuvash polycythemia (CP) is an autosomal recessive human disorder in which the regulatory degradation of HIF is impaired, resulting in elevated levels of HIF at normal oxygen tensions."1.36Regulation of human metabolism by hypoxia-inducible factor. ( Cheeseman, J; Clarke, K; Constantin-Teodosiu, D; Dorrington, KL; Edwards, LM; Emmanuel, Y; Formenti, F; Frayn, KN; Greenhaff, PL; Humphreys, SM; Karpe, F; Lappin, TR; McMullin, MF; McNamara, CJ; Mills, W; Murphy, JA; O'Connor, DF; Percy, MJ; Ratcliffe, PJ; Robbins, PA; Smith, TG; Treacy, M, 2010)
"Methylene blue was then administered intravenously to facilitate conversion of methemoglobin to oxyhemoglobin, which increased oxygen content (12."1.33Regulation of oxygen delivery during induced polycythemia in exercising dogs. ( Horwitz, LD; Lindenfeld, J; Travis, VL; Weil, JV, 2005)
"With normovolemic polycythemia, cardiac output fell in a linear fashion as hematocrit was increased to 65%, but these changes were balanced by an increasing oxygen content resulting in constant systemic oxygen transport."1.27Hemodynamic response to normovolemic polycythemia at rest and during exercise in dogs. ( Horwitz, LD; Lindenfeld, J; Travis, VL; Weil, JV, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
van de Sande, MJA1
Lopriore, E1
Verweij, EJT1
de Bruin, C1
Slaghekke, F1
Tollenaar, LSA1
Formenti, F1
Constantin-Teodosiu, D1
Emmanuel, Y1
Cheeseman, J1
Dorrington, KL1
Edwards, LM1
Humphreys, SM1
Lappin, TR1
McMullin, MF1
McNamara, CJ1
Mills, W1
Murphy, JA1
O'Connor, DF1
Percy, MJ1
Ratcliffe, PJ1
Smith, TG1
Treacy, M1
Frayn, KN1
Greenhaff, PL1
Karpe, F1
Clarke, K1
Robbins, PA1
Lindenfeld, J2
Weil, JV2
Travis, VL2
Horwitz, LD2
Frangioni, G2
Borgioli, G2
Rosenkrantz, TS1
Philipps, AF1
Knox, I1
Zalneraitis, EL1
Porte, PJ1
Skrzypczak, PE1
Raye, JR1
Spriet, LL1
Gledhill, N1
Froese, AB1
Wilkes, DL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Endogenous Iron Status and Intravenous Iron on Human Skeletal Muscle Metabolism at Rest and During Exercise[NCT02308449]29 participants (Actual)Interventional2014-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for lactic acid and Erythrocytosis

ArticleYear
Lactate acidosis and hypoglycaemia in twin anaemia polycythemia sequence donors.
    Archives of disease in childhood. Fetal and neonatal edition, 2023, Volume: 108, Issue:3

    Topics: Female; Fetofetal Transfusion; Humans; Hypoglycemia; Lactic Acid; Placenta; Polycythemia; Pregnancy;

2023
Regulation of human metabolism by hypoxia-inducible factor.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jul-13, Volume: 107, Issue:28

    Topics: Adult; Exercise; Female; Gene Expression Regulation; Humans; Hypoxia; Lactates; Lactic Acid; Male; M

2010
Regulation of oxygen delivery during induced polycythemia in exercising dogs.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:5

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Blood Viscosity; Cardiac Output; Dogs; Erythrocyte Tran

2005
J10 lactate-induced polycythemia in newts.
    The Journal of experimental zoology, 1983, Volume: 225, Issue:1

    Topics: Alkalosis; Animals; Erythrocyte Count; Lactates; Lactic Acid; Polycythemia; Pyruvates; Pyruvic Acid;

1983
[Experimental polycythemia induced by lactate in Tritons].
    Bollettino della Societa italiana di biologia sperimentale, 1982, Apr-15, Volume: 58, Issue:7

    Topics: Animals; Erythrocyte Count; Erythropoiesis; Female; Hypoxia; Lactates; Lactic Acid; Male; Polycythem

1982
Regulation of cerebral glucose metabolism in normal and polycythemic newborn lambs.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Brain; Cerebrovascular Circulation; Electroencepha

1992
Effect of graded erythrocythemia on cardiovascular and metabolic responses to exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Blood Pressure; Blood Transfusion, Autologous; Cardiac Output; Heart R

1986
Hemodynamic response to normovolemic polycythemia at rest and during exercise in dogs.
    Circulation research, 1985, Volume: 56, Issue:6

    Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Lactates; Lac

1985