lactic acid has been researched along with Endometrioma in 14 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leuprolide acetate is a highly potent analog of luteinizing hormone-releasing hormone." | 5.27 | One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. ( Heya, T; Ogawa, Y; Okada, H; Shimamoto, T, 1988) |
| "The pathological expression and function of lactate dehydrogenase A (LDHA), a key enzyme that converts pyruvate into lactic acid during glycolysis, remains unknown in endometriosis." | 4.02 | Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis. ( Dai, Y; Huang, Q; Jin, X; Lin, X; Liu, N; Shi, L; Zhang, S; Zheng, J; Zhou, F, 2021) |
| "The aim of this study was to determine whether endometrioma resection alters most commonly defined endometrial metabolites, lactate (Lac), N-acetylaspartate (NAA), creatine 1 (Cr1), creatine 2 (Cr2), and choline (Cho) during the window of implantation." | 3.85 | Impact of Endometrioma Resection on Eutopic Endometrium Metabolite Contents: Noninvasive Evaluation of Endometrium Receptivity. ( Acet, M; Acet, T; Bozkurt, DK; Celik, O; Ersahin, A; Ersahin, S; Ilhan, S; Yavuz, Y, 2017) |
| " Studies on the dosage design of this new delivery system of leuprorelin are summarized." | 2.38 | [Once-a-month injectable microcapsules of leuprorelin acetate]. ( Ogawa, Y; Okada, H; Toguchi, H; Yamamoto, M, 1991) |
| "Endometriosis is a gynaecological condition characterized by the growth of endometrium-like tissues within and outside of the pelvic cavity." | 1.91 | Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis. ( Cao, Y; Gou, Y; Jiao, N; Wang, B; Wang, H; Wang, T; Yu, Y; Zhang, Z, 2023) |
| "Endometriosis is a common disease in women of childbearing age and is closely associated with female infertility." | 1.72 | Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis. ( Cai, L; Cui, Y; Liu, J; Mao, J; Mao, Y; Zhang, J, 2022) |
| "Endometriosis is a chronic hormonal inflammatory disease characterized by the presence of endometrial tissue outside the uterus." | 1.62 | HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression. ( Ren, C; Wang, Y; Xiu, J; Yang, T; Yu, Z, 2021) |
| "Endometriosis is a common gynecological disease, which is defined as the growth of endometrial tissues outside the uterine cavity." | 1.51 | Induction of Pyruvate Dehydrogenase Kinase 1 by Hypoxia Alters Cellular Metabolism and Inhibits Apoptosis in Endometriotic Stromal Cells. ( Lee, HC; Lin, SC; Tsai, SJ; Wu, MH, 2019) |
| "The serum metabolomics signature of endometrial cancer patients is peculiar because it differs from that of healthy controls and from that of benign endometrial disease and from other gynecological cancers (such as ovarian cancer)." | 1.48 | Metabolomic Signature of Endometrial Cancer. ( Di Cello, A; Guida, M; Landolfi, A; Martinelli, P; Sarno, L; Scala, G; Troisi, J; Venturella, R; Zullo, F, 2018) |
| "Leuprolide acetate is a highly potent analog of luteinizing hormone-releasing hormone." | 1.27 | One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. ( Heya, T; Ogawa, Y; Okada, H; Shimamoto, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, J | 1 |
| Zhang, J | 1 |
| Cai, L | 1 |
| Cui, Y | 2 |
| Liu, J | 2 |
| Mao, Y | 2 |
| Gou, Y | 1 |
| Wang, H | 3 |
| Wang, T | 1 |
| Wang, B | 1 |
| Jiao, N | 1 |
| Yu, Y | 1 |
| Cao, Y | 1 |
| Zhang, Z | 1 |
| Wang, Y | 1 |
| Xiu, J | 1 |
| Yang, T | 1 |
| Ren, C | 1 |
| Yu, Z | 1 |
| Zheng, J | 1 |
| Dai, Y | 1 |
| Lin, X | 1 |
| Huang, Q | 1 |
| Shi, L | 1 |
| Jin, X | 1 |
| Liu, N | 1 |
| Zhou, F | 1 |
| Zhang, S | 1 |
| Marianna, S | 1 |
| Alessia, P | 1 |
| Susan, C | 1 |
| Francesca, C | 2 |
| Angela, S | 1 |
| Antonella, N | 1 |
| Patrizia, I | 1 |
| Nicola, C | 1 |
| Emilio, C | 1 |
| Troisi, J | 1 |
| Sarno, L | 1 |
| Landolfi, A | 1 |
| Scala, G | 1 |
| Martinelli, P | 1 |
| Venturella, R | 1 |
| Di Cello, A | 1 |
| Zullo, F | 1 |
| Guida, M | 1 |
| Lee, HC | 1 |
| Lin, SC | 1 |
| Wu, MH | 1 |
| Tsai, SJ | 1 |
| Young, VJ | 1 |
| Brown, JK | 1 |
| Maybin, J | 1 |
| Saunders, PT | 1 |
| Duncan, WC | 1 |
| Horne, AW | 1 |
| Qi, X | 1 |
| Zhang, Y | 1 |
| Ji, H | 1 |
| Wu, X | 1 |
| Wang, F | 1 |
| Xie, M | 1 |
| Shu, L | 1 |
| Jiang, S | 1 |
| Ersahin, A | 1 |
| Celik, O | 1 |
| Acet, M | 1 |
| Ersahin, S | 1 |
| Acet, T | 1 |
| Bozkurt, DK | 1 |
| Yavuz, Y | 1 |
| Ilhan, S | 1 |
| Liu, Q | 1 |
| Ma, P | 1 |
| Liu, L | 1 |
| Ma, G | 1 |
| Ma, J | 1 |
| Liu, X | 1 |
| Liu, Y | 1 |
| Lin, W | 1 |
| Zhu, Y | 1 |
| de Almeida Borges, VR | 1 |
| Tavares, MR | 1 |
| da Silva, JH | 1 |
| Tajber, L | 1 |
| Boylan, F | 1 |
| Ribeiro, AF | 1 |
| Nasciutti, LE | 1 |
| Cabral, LM | 1 |
| de Sousa, VP | 1 |
| Toguchi, H | 1 |
| Ogawa, Y | 2 |
| Okada, H | 2 |
| Yamamoto, M | 1 |
| Heya, T | 1 |
| Shimamoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of a Combined Treatment With Myo-inositol, D-chiro-inositol and Glucomannan in Women With PCOS[NCT03608813] | 120 participants (Actual) | Observational | 2016-09-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lactic acid and Endometrioma
| Article | Year |
|---|---|
[Once-a-month injectable microcapsules of leuprorelin acetate].
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Capsules; Delayed-Action Preparations; Drug Delivery | 1991 |
13 other studies available for lactic acid and Endometrioma
| Article | Year |
|---|---|
Elevated prohibitin 1 expression mitigates glucose metabolism defects in granulosa cells of infertile patients with endometriosis.
Topics: Endometriosis; Female; Glucose; Granulosa Cells; Humans; Infertility; Lactic Acid; Prohibitins; Repr | 2022 |
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Topics: Animals; Endometriosis; Female; Humans; Intracellular Signaling Peptides and Proteins; Lactic Acid; | 2023 |
HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression.
Topics: Aminopyridines; Animals; Blotting, Western; Cell Count; Cell Line; Cell Movement; Cell Proliferation | 2021 |
Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis.
Topics: Adult; Apoptosis; Cell Proliferation; Endometriosis; Endometrium; Epithelial Cells; Epithelial-Mesen | 2021 |
Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.
Topics: Adult; Chemokine CCL11; Chemokine CXCL10; Endometriosis; Female; Follicular Fluid; Humans; Insulin; | 2017 |
Metabolomic Signature of Endometrial Cancer.
Topics: 3-Hydroxybutyric Acid; Aged; Biomarkers, Tumor; Case-Control Studies; Diagnosis, Differential; Endom | 2018 |
Induction of Pyruvate Dehydrogenase Kinase 1 by Hypoxia Alters Cellular Metabolism and Inhibits Apoptosis in Endometriotic Stromal Cells.
Topics: Apoptosis; Cell Hypoxia; Cells, Cultured; Endometriosis; Female; Gene Expression; Gene Expression Re | 2019 |
Transforming growth factor-β induced Warburg-like metabolic reprogramming may underpin the development of peritoneal endometriosis.
Topics: Ascitic Fluid; Cell Line, Transformed; Endometriosis; Endometrium; Epithelial Cells; Female; Glucose | 2014 |
Knockdown of prohibitin expression promotes glucose metabolism in eutopic endometrial stromal cells from women with endometriosis.
Topics: Adult; Endometriosis; Endometrium; Female; Gene Knockdown Techniques; Glucose; Humans; In Vitro Tech | 2014 |
Impact of Endometrioma Resection on Eutopic Endometrium Metabolite Contents: Noninvasive Evaluation of Endometrium Receptivity.
Topics: Adult; Aspartic Acid; Choline; Creatine; Endometriosis; Endometrium; Female; Humans; Lactic Acid; Ma | 2017 |
Evaluation of PLGA containing anti-CTLA4 inhibited endometriosis progression by regulating CD4+CD25+Treg cells in peritoneal fluid of mouse endometriosis model.
Topics: Animals; Antibodies; Ascitic Fluid; Cell Culture Techniques; Cell Proliferation; CTLA-4 Antigen; Dru | 2017 |
Development and characterization of poly(lactic-co-glycolic) acid nanoparticles loaded with copaiba oleoresin.
Topics: Cell Survival; Cells, Cultured; Drug Carriers; Endometriosis; Fabaceae; Female; Freeze Drying; Human | 2018 |
One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats.
Topics: Animals; Capsules; Delayed-Action Preparations; Endometriosis; Estradiol; Female; Follicle Stimulati | 1988 |