lactic acid has been researched along with Emesis in 15 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastric beriberi is a rare presentation of TD that can lead to severe GI symptoms and lactic acidosis." | 8.12 | Clinical profile of patients presenting with thiamine-responsive upper-gastrointestinal upset: A pointer toward gastric beriberi. ( Ganie, MA; Kareem, O; Muzaffer, U; Nisar, S; Tanvir, M; Wani, IA, 2022) |
| "Gastric beriberi is a rare presentation of TD that can lead to severe GI symptoms and lactic acidosis." | 4.12 | Clinical profile of patients presenting with thiamine-responsive upper-gastrointestinal upset: A pointer toward gastric beriberi. ( Ganie, MA; Kareem, O; Muzaffer, U; Nisar, S; Tanvir, M; Wani, IA, 2022) |
| " His blood gas analysis showed a metabolic acidosis caused by renal failure and lactic acidosis combined with a hypochloraemic alkalosis." | 3.73 | [A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue]. ( Bedock, B; Dumaine, A; Gauclère, V; Legrand, E; Proust, P; Rozière, A; Tayssir, A, 2006) |
| "Manifestations suggestive of migraine were present in each child." | 2.40 | Mitochondrial disease and cyclic vomiting syndrome. ( Boles, RG; Williams, JC, 1999) |
| " Adverse events included rising serum lactate (30." | 1.39 | Tolerability and safety of enteral nutrition in critically ill patients receiving intravenous vasopressor therapy. ( Mancl, EE; Muzevich, KM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nisar, S | 1 |
| Tanvir, M | 1 |
| Ganie, MA | 1 |
| Kareem, O | 1 |
| Muzaffer, U | 1 |
| Wani, IA | 1 |
| Nuzzo, A | 1 |
| Joly, F | 1 |
| Ronot, M | 1 |
| Castier, Y | 1 |
| Huguet, A | 1 |
| Paugam-Burtz, C | 1 |
| Cazals-Hatem, D | 1 |
| Tran-Dinh, A | 1 |
| Becq, A | 1 |
| Panis, Y | 1 |
| Bouhnik, Y | 1 |
| Maggiori, L | 1 |
| Corcos, O | 1 |
| Parente, CS | 1 |
| Sandland-Taylor, LE | 1 |
| Akhtar, W | 1 |
| Kalantar-Zadeh, K | 1 |
| Uppot, RN | 1 |
| Lewandrowski, KB | 1 |
| Baur, DA | 1 |
| Schroer, AB | 1 |
| Luden, ND | 1 |
| Womack, CJ | 1 |
| Smyth, SA | 1 |
| Saunders, MJ | 1 |
| Thanachartwet, V | 1 |
| Oer-Areemitr, N | 1 |
| Chamnanchanunt, S | 1 |
| Sahassananda, D | 1 |
| Jittmittraphap, A | 1 |
| Suwannakudt, P | 1 |
| Desakorn, V | 1 |
| Wattanathum, A | 1 |
| Beharrysingh, R | 1 |
| McDaniel, JL | 1 |
| Abdel Hak, A | 1 |
| Voore, N | 1 |
| Abandeh, FI | 1 |
| Young, DS | 1 |
| Miller, ES | 1 |
| Bhatia, K | 1 |
| Mancl, EE | 1 |
| Muzevich, KM | 1 |
| Zouaoui, K | 1 |
| Dulaurent, S | 1 |
| Gaulier, JM | 1 |
| Moesch, C | 1 |
| Lachâtre, G | 1 |
| Lichterfeld, M | 1 |
| Fischer, HP | 1 |
| Spengler, U | 1 |
| Rockstroh, JK | 1 |
| Dumaine, A | 1 |
| Tayssir, A | 1 |
| Gauclère, V | 1 |
| Proust, P | 1 |
| Legrand, E | 1 |
| Rozière, A | 1 |
| Bedock, B | 1 |
| McTague, JA | 1 |
| Forney, R | 1 |
| Boles, RG | 1 |
| Williams, JC | 1 |
| Strachan, J | 1 |
| McLellan, A | 1 |
| Kirkpatrick, M | 1 |
| Hume, R | 1 |
| Mechan, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159] | Phase 2 | 140 participants (Actual) | Interventional | 2018-02-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Arm | 2.9 |
| Placebo Arm | 1.93 |
Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 11.5 |
| Placebo Arm | 11 |
In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 11 |
| Placebo Arm | 13 |
Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.
| Intervention | days (Mean) |
|---|---|
| Treatment Arm | 4.76 |
| Placebo Arm | 4.66 |
ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 6 |
| Placebo Arm | 10 |
PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | Percent (Mean) |
|---|---|
| Treatment Arm | 63 |
| Placebo Arm | 58 |
Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.
| Intervention | hours (Mean) |
|---|---|
| HAT Treatment | 27 |
| Comparator | 53 |
Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 22 |
| Placebo Arm | 22.4 |
2 reviews available for lactic acid and Emesis
| Article | Year |
|---|---|
Jamaican vomiting sickness in Toledo, Ohio.
Topics: Adipates; Adult; Chromatography, Gas; Emergency Service, Hospital; Female; Fluid Therapy; Fruit; Hum | 1994 |
Mitochondrial disease and cyclic vomiting syndrome.
Topics: Adolescent; Adult; Child; Child, Preschool; DNA Mutational Analysis; DNA, Mitochondrial; Female; Hum | 1999 |
1 trial available for lactic acid and Emesis
| Article | Year |
|---|---|
Glucose-fructose enhances performance versus isocaloric, but not moderate, glucose.
Topics: Administration, Oral; Adult; Athletic Performance; Bicycling; Blood Glucose; Colic; Dizziness; Doubl | 2014 |
12 other studies available for lactic acid and Emesis
| Article | Year |
|---|---|
Clinical profile of patients presenting with thiamine-responsive upper-gastrointestinal upset: A pointer toward gastric beriberi.
Topics: Adult; Aged; Beriberi; Gastrointestinal Diseases; Humans; Lactic Acid; Middle Aged; Nausea; Thiamine | 2022 |
Normal Lactate and Unenhanced CT-Scan Result in Delayed Diagnosis of Acute Mesenteric Ischemia.
Topics: Abdominal Pain; Acute Disease; Adult; Anastomosis, Surgical; Chronic Disease; Cohort Studies; Colon; | 2020 |
Diagnostic challenge: an atypical presentation of infective endocarditis.
Topics: Bacteremia; Blood Culture; C-Reactive Protein; Diagnosis, Differential; Diarrhea; Dysentery; Early W | 2021 |
Case records of the Massachusetts General Hospital. Case 23-2013. A 54-year-old woman with abdominal pain, vomiting, and confusion.
Topics: Abdominal Pain; Acidosis, Lactic; Confusion; Diabetes Mellitus, Type 2; Diagnosis, Differential; Fem | 2013 |
Identification of clinical factors associated with severe dengue among Thai adults: a prospective study.
Topics: Adolescent; Adult; Age Factors; Child; Dengue Virus; Female; Hemorrhage; Humans; Lactic Acid; Logist | 2015 |
A Break in the Wall: Stercoral Colitis.
Topics: Abdomen; Aged; Cervical Cord; Colitis; Confusion; Fatal Outcome; Fecal Impaction; Female; Hospice Ca | 2016 |
Fever and Malaise in an Infant.
Topics: Anti-Bacterial Agents; Antimalarials; Babesiosis; Clindamycin; Diagnosis, Differential; Doxycycline; | 2017 |
Tolerability and safety of enteral nutrition in critically ill patients receiving intravenous vasopressor therapy.
Topics: Administration, Intravenous; Adult; Aged; Critical Illness; Dose-Response Relationship, Drug; Entera | 2013 |
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro | 2013 |
[Fatty liver and increased serum lactate in a woman with HIV].
Topics: Abdominal Pain; Antiretroviral Therapy, Highly Active; Biopsy; Fatty Liver; Female; Hepatomegaly; HI | 2003 |
[A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue].
Topics: Acid-Base Imbalance; Acidosis; Acute Kidney Injury; Adult; Alkalosis; Blood Chemical Analysis; Blood | 2006 |
Ketoacidosis: an unusual presentation of MELAS.
Topics: Blood Glucose; C-Reactive Protein; Cerebral Infarction; Child; Creatinine; Humans; Ketosis; Lactic A | 2001 |