lactic acid has been researched along with Embryopathies in 33 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies in healthy patients undergoing elective caesarean delivery show that, compared with phenylephrine, ephedrine used to treat spinal hypotension is associated with increased fetal acidosis." | 9.27 | A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise. ( Adams, SC; Arcache, MJ; Dyer, RA; Emmanuel, A; Higgins, N; James, MF; Joolay, Y; Lombard, CJ; Reed, AR; Schulein, S; van Dyk, D; Vorster, A; Wong, CA, 2018) |
| " We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome." | 7.72 | Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model. ( Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Räsänen, J, 2004) |
| "Studies in healthy patients undergoing elective caesarean delivery show that, compared with phenylephrine, ephedrine used to treat spinal hypotension is associated with increased fetal acidosis." | 5.27 | A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise. ( Adams, SC; Arcache, MJ; Dyer, RA; Emmanuel, A; Higgins, N; James, MF; Joolay, Y; Lombard, CJ; Reed, AR; Schulein, S; van Dyk, D; Vorster, A; Wong, CA, 2018) |
| " We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome." | 3.72 | Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model. ( Alahuhta, S; Erkinaro, T; Kavasmaa, T; Mäkikallio, K; Räsänen, J, 2004) |
| " The diagnosis of pyruvate dehydrogenase deficiency was made in the presenting fetus after delivery on the basis of subsequent mortality from severe lactic acidosis." | 3.71 | Prenatal diagnosis of pyruvate dehydrogenase deficiency using magnetic resonance imaging. ( Brown, SA; Mulkern, R; Norwitz, ER; Robinson, JN; Rybicki, F; Tempany, CM, 2001) |
| " Captopril treatment, which reduces maternal blood pressure, during pregnancy and lactation, is reported to have a beneficial effect postnatally, normalizing the blood pressure of offspring in the SHR." | 3.70 | Effects of maternal captopril treatment on growth, blood glucose and plasma insulin in the fetal spontaneously hypertensive rat. ( Bassett, NS; Batchelor, DC; Johnston, BM; Lewis, RM; Skinner, SJ; Vickers, MH, 1999) |
| " Of the 24 fetuses with normal heart rates and abnormal velocimetry, 4 (17 percent) had moderate lactic acidosis, 1 (4 percent) had a low pH value, and 3 (12 percent) had hypoxia." | 3.68 | Diagnostic value of blood sampling in fetuses with growth retardation. ( Battaglia, FC; Bozzetti, P; Buscaglia, M; Cetin, I; Ferrazzi, E; Lanfranchi, A; Marconi, AM; Pardi, G, 1993) |
| "Congenital heart disease is the leading cause of death in the first year after birth." | 1.31 | Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient. ( Bennink, GB; Brenner, JI; Copel, JA; Hitchcock, JF; Kleinman, CS; Lisowski, LA; Meijboom, EJ; Stoutenbeek, P; Verheijen, PM, 2001) |
| "Induced fetal hypoxemia resulted in a lactic metabolic acidosis that progressively worsened, with death occurring in three of the animals during the early recovery period." | 1.29 | Recovery of the ovine fetus from sustained hypoxia: effects on endocrine, cardiovascular, and biophysical activity. ( Carmichael, L; Fraher, L; Matsuda, Y; Patrick, J; Richardson, B, 1994) |
| "Induced fetal hypoxemia resulted in a progressive lactic metabolic acidosis; however, all fetuses had recovered within 24 hours." | 1.28 | Effects of sustained hypoxemia on the sheep fetus at midgestation: endocrine, cardiovascular, and biophysical responses. ( Carmichael, L; Challis, J; Matsuda, Y; Patrick, J; Richardson, B, 1992) |
| "To test the hypothesis that long-term hypoxemia affects fetal cardiac function, we measured right (RVO) and left (LVO) ventricular output by electromagnetic flow probes." | 1.28 | Right and left ventricular function in fetal sheep exposed to long-term high-altitude hypoxemia. ( Gilbert, RD; Kamitomo, M; Longo, LD, 1992) |
| "The effects of prolonged mild hypoxemia on the fetus have received little attention." | 1.27 | The effect of mild hypoxemia maintained for twenty-four hours on maternal and fetal glucose, lactate, cortisol, and arginine vasopressin in pregnant sheep at 122 to 139 days' gestation. ( Elias, B; Figueroa, J; Markowitz, S; Nathanielsz, P; Towell, ME, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 13 (39.39) | 18.2507 |
| 2000's | 11 (33.33) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Surmeli Onay, O | 1 |
| Korkmaz, A | 1 |
| Yigit, S | 1 |
| Yurdakok, M | 1 |
| Holzmann, M | 1 |
| Nordström, L | 2 |
| Steer, P | 1 |
| Dyer, RA | 1 |
| Emmanuel, A | 1 |
| Adams, SC | 1 |
| Lombard, CJ | 1 |
| Arcache, MJ | 1 |
| Vorster, A | 1 |
| Wong, CA | 1 |
| Higgins, N | 1 |
| Reed, AR | 1 |
| James, MF | 1 |
| Joolay, Y | 1 |
| Schulein, S | 1 |
| van Dyk, D | 1 |
| Andresen, JH | 1 |
| Saugstad, OD | 1 |
| Labrecque, L | 1 |
| Provençal, M | 1 |
| Caqueret, A | 1 |
| Wo, BL | 1 |
| Bujold, E | 1 |
| Larivière, F | 1 |
| Bédard, MJ | 1 |
| Torrance, HL | 1 |
| Pistorius, L | 1 |
| Voorbij, HA | 1 |
| Visser, GH | 1 |
| Hunter, CJ | 1 |
| Bennet, L | 1 |
| Power, GG | 1 |
| Roelfsema, V | 1 |
| Blood, AB | 1 |
| Quaedackers, JS | 1 |
| George, S | 1 |
| Guan, J | 1 |
| Gunn, AJ | 1 |
| Erkinaro, T | 2 |
| Mäkikallio, K | 2 |
| Kavasmaa, T | 2 |
| Alahuhta, S | 1 |
| Räsänen, J | 2 |
| Acharya, G | 1 |
| Haapsamo, M | 1 |
| Mertens, L | 1 |
| Huhta, JC | 1 |
| Gjerris, AC | 1 |
| Staer-Jensen, J | 1 |
| Jørgensen, JS | 1 |
| Bergholt, T | 1 |
| Nickelsen, C | 1 |
| Cooper, D | 1 |
| Sharma, S | 1 |
| Orakkan, P | 1 |
| Franke, U | 1 |
| Kwan, E | 1 |
| Rurak, DW | 2 |
| Taylor, SM | 2 |
| Westgren, M | 2 |
| Lingman, G | 1 |
| Stangenberg, M | 1 |
| Davis, LE | 1 |
| Hohimer, AR | 2 |
| Woods, LL | 1 |
| Matsuda, Y | 2 |
| Patrick, J | 2 |
| Carmichael, L | 2 |
| Fraher, L | 1 |
| Richardson, B | 2 |
| Cock, ML | 1 |
| Wlodek, ME | 1 |
| Hooper, SB | 1 |
| McCrabb, GJ | 1 |
| Harding, R | 1 |
| Pardi, G | 1 |
| Cetin, I | 1 |
| Marconi, AM | 1 |
| Lanfranchi, A | 1 |
| Bozzetti, P | 1 |
| Ferrazzi, E | 1 |
| Buscaglia, M | 1 |
| Battaglia, FC | 1 |
| Cohn, HE | 1 |
| Piasecki, GJ | 1 |
| Cohen, WR | 1 |
| Jackson, BT | 1 |
| Krüger, K | 1 |
| Kublickas, M | 1 |
| Liu, KZ | 1 |
| Mantsch, HH | 1 |
| Lewis, RM | 1 |
| Vickers, MH | 1 |
| Batchelor, DC | 1 |
| Bassett, NS | 1 |
| Johnston, BM | 1 |
| Skinner, SJ | 1 |
| Giussani, DA | 2 |
| Gardner, DS | 2 |
| Cox, DT | 1 |
| Fletcher, AJ | 2 |
| Verheijen, PM | 1 |
| Lisowski, LA | 1 |
| Stoutenbeek, P | 1 |
| Hitchcock, JF | 1 |
| Brenner, JI | 1 |
| Copel, JA | 1 |
| Kleinman, CS | 1 |
| Meijboom, EJ | 1 |
| Bennink, GB | 1 |
| Robinson, JN | 1 |
| Norwitz, ER | 1 |
| Mulkern, R | 1 |
| Brown, SA | 1 |
| Rybicki, F | 1 |
| Tempany, CM | 1 |
| Arnon, S | 1 |
| Aviram, R | 1 |
| Dolfin, T | 1 |
| Regev, R | 1 |
| Litmanovits, I | 1 |
| Tepper, R | 1 |
| Elpeleg, ON | 1 |
| Bloomfield, MR | 1 |
| Fowden, AL | 1 |
| Challis, J | 1 |
| Kamitomo, M | 1 |
| Longo, LD | 1 |
| Gilbert, RD | 1 |
| Chao, CR | 1 |
| Bissonnette, JM | 1 |
| Piquard, F | 1 |
| Hsiung, R | 1 |
| Schaefer, A | 1 |
| Haberey, P | 1 |
| Dellenbach, P | 1 |
| Towell, ME | 1 |
| Figueroa, J | 1 |
| Markowitz, S | 1 |
| Elias, B | 1 |
| Nathanielsz, P | 1 |
| Cooper, CC | 1 |
1 review available for lactic acid and Embryopathies
| Article | Year |
|---|---|
Lactate measurements in scalp and cord arterial blood.
Topics: Acid-Base Imbalance; Biomarkers; Female; Fetal Blood; Fetal Diseases; Fetal Hypoxia; Humans; Hypoxia | 2001 |
1 trial available for lactic acid and Embryopathies
| Article | Year |
|---|---|
A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise.
Topics: Acidosis; Adult; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Ephedrine; Female; Fetal | 2018 |
31 other studies available for lactic acid and Embryopathies
| Article | Year |
|---|---|
Hypoxic-ischemic enterocolitis: a proposal of a new terminology for early NEC or NEC-like disease in preterm infants, a single-center prospective observational study.
Topics: Biomarkers; Case-Control Studies; Enterocolitis, Necrotizing; Fatty Acid-Binding Proteins; Female; F | 2020 |
Inconsistency between lactate meters in the assessment of fetal metabolic acidemia.
Topics: Acidosis; Female; Fetal Blood; Fetal Diseases; Fetal Monitoring; Humans; Lactic Acid; Pregnancy; Ref | 2021 |
50 Years Ago in The Journal of Pediatrics: Acid-Base Monitoring of the Fetus during Labor with Blood Obtained from the Scalp.
Topics: Acid-Base Equilibrium; Acidosis; Blood Specimen Collection; Female; Fetal Diseases; Fetal Monitoring | 2019 |
Correlation of cord blood pH, base excess, and lactate concentration measured with a portable device for identifying fetal acidosis.
Topics: Acidosis; Fetal Blood; Fetal Diseases; Humans; Hydrogen-Ion Concentration; Lactic Acid; Prenatal Dia | 2014 |
Lactate to creatinine ratio in amniotic fluid: a pilot study.
Topics: Acidosis, Lactic; Amniotic Fluid; Biomarkers; Cesarean Section; Creatinine; Female; Fetal Blood; Fet | 2013 |
Key neuroprotective role for endogenous adenosine A1 receptor activation during asphyxia in the fetal sheep.
Topics: Animals; Asphyxia; Blood Gas Analysis; Body Temperature; Brain; Calorimetry; Cell Count; Cerebrovasc | 2003 |
Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model.
Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Ani | 2004 |
Metabolic acidosis decreases fetal myocardial isovolumic velocities in a chronic sheep model of increased placental vascular resistance.
Topics: Acidosis; Acute Disease; Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Chronic D | 2008 |
Umbilical cord blood lactate: a valuable tool in the assessment of fetal metabolic acidosis.
Topics: Acidosis, Lactic; Blood Gas Analysis; Fetal Blood; Fetal Diseases; Humans; Infant, Newborn; Lactic A | 2008 |
Does placental lactate production have a role in ephedrine-induced fetal metabolic acidosis?
Topics: Acidosis; Cesarean Section; Ephedrine; Female; Fetal Diseases; Humans; Lactic Acid; Maternal-Fetal E | 2008 |
Oxygen consumption, acid-base status, and behavior during and after acute, severe hemorrhage in fetal lambs.
Topics: Acid-Base Equilibrium; Acute Disease; Animals; Behavior, Animal; Blood Glucose; Blood Pressure; Elec | 1995 |
Oxygenation of the human fetus as a function of hemoglobulin concentration.
Topics: Acid-Base Equilibrium; Female; Fetal Blood; Fetal Diseases; Fetal Hemoglobin; Fetus; Humans; Lactate | 1994 |
Renal function during chronic anemia in the ovine fetus.
Topics: Amniotic Fluid; Anemia; Animals; Biological Availability; Chronic Disease; Fetal Diseases; Fetus; Gl | 1994 |
Recovery of the ovine fetus from sustained hypoxia: effects on endocrine, cardiovascular, and biophysical activity.
Topics: Animals; Blood Glucose; Carbon Dioxide; Cardiovascular System; Electrophysiology; Endocrine Glands; | 1994 |
The effects of twenty-four hours of reduced uterine blood flow on fetal fluid balance in sheep.
Topics: Amniotic Fluid; Animals; Deglutition; Diuresis; Electrolytes; Female; Fetal Blood; Fetal Diseases; F | 1994 |
Diagnostic value of blood sampling in fetuses with growth retardation.
Topics: Acidosis; Amino Acids; Cordocentesis; Delivery, Obstetric; Female; Fetal Diseases; Fetal Growth Reta | 1993 |
The adrenal secretion of catecholamines during systemic metabolic acidosis in fetal sheep.
Topics: Acidosis; Adrenal Medulla; Animals; Arteries; Blood Glucose; Carbon Dioxide; Catecholamines; Epineph | 1997 |
Lactate in scalp and cord blood from fetuses with ominous fetal heart rate patterns.
Topics: Female; Fetal Blood; Fetal Diseases; Heart Rate, Fetal; Humans; Lactic Acid; Pregnancy; Prospective | 1998 |
Simultaneous quantitation from infrared spectra of glucose concentrations, lactate concentrations, and lecithin/sphingomyelin ratios in amniotic fluid.
Topics: Amniotic Fluid; Female; Fetal Diseases; Fetal Distress; Fetal Organ Maturity; Glucose; Humans; Lacti | 1999 |
Effects of maternal captopril treatment on growth, blood glucose and plasma insulin in the fetal spontaneously hypertensive rat.
Topics: Animals; Blood Glucose; Captopril; Drinking; Female; Fetal Blood; Fetal Diseases; Fetal Weight; Gest | 1999 |
Purinergic contribution to circulatory, metabolic, and adrenergic responses to acute hypoxemia in fetal sheep.
Topics: Animals; Blood Glucose; Blood Pressure; Catecholamines; Epinephrine; Female; Femoral Artery; Fetal B | 2001 |
Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient.
Topics: Acidosis; Cardiac Surgical Procedures; Female; Fetal Diseases; Gestational Age; Heart Defects, Conge | 2001 |
Prenatal diagnosis of pyruvate dehydrogenase deficiency using magnetic resonance imaging.
Topics: Acidosis, Lactic; Adult; Cerebral Cortex; Cerebral Ventricles; Cerebrospinal Fluid; Diseases in Twin | 2001 |
Mitochondrial DNA depletion presenting prenatally with skin edema and multisystem disease immediately after birth.
Topics: Consanguinity; DNA; DNA, Mitochondrial; Edema; Female; Fetal Diseases; Fetal Movement; Gestational A | 2002 |
Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus.
Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Adrenocorticotropic Hormone; Animals; Blood Gas Anal | 2002 |
Effects of sustained hypoxemia on the sheep fetus at midgestation: endocrine, cardiovascular, and biophysical responses.
Topics: Animals; Blood Glucose; Carbon Dioxide; Cardiovascular System; Endocrine Glands; Female; Fetal Disea | 1992 |
Right and left ventricular function in fetal sheep exposed to long-term high-altitude hypoxemia.
Topics: Altitude; Animals; Cardiac Output; Catecholamines; Fetal Diseases; Fetal Heart; Gases; Hemodynamics; | 1992 |
Fetal cerebral blood flow and metabolism during oligemia and early postoligemic reperfusion.
Topics: Animals; Arteries; Blood Glucose; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencepha | 1991 |
Does fetal acidosis develop with maternal glucose infusion during normal labor?
Topics: Acidosis; Adult; Female; Fetal Diseases; Fetal Distress; Glucose; Humans; Hyperglycemia; Isotonic So | 1989 |
The effect of mild hypoxemia maintained for twenty-four hours on maternal and fetal glucose, lactate, cortisol, and arginine vasopressin in pregnant sheep at 122 to 139 days' gestation.
Topics: Animals; Arginine Vasopressin; Blood Glucose; Female; Fetal Blood; Fetal Diseases; Gestational Age; | 1987 |
Fetal oxygen consumption and PO2 during hypercapnia in pregnant sheep.
Topics: Animals; Blood Glucose; Blood Pressure; Female; Fetal Diseases; Heart Rate; Hypercapnia; Lactates; L | 1986 |