Page last updated: 2024-10-17

lactic acid and Edema

lactic acid has been researched along with Edema in 34 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
" Pathological metabolic shift and subsequent lactic acid production are thought to play an important role in diverse painful states; however, their contribution to inflammation-driven pain is still to be comprehended."7.81Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis. ( Go, Y; Harris, RA; Jeoung, NH; Jha, MK; Kook, H; Lee, IK; Lee, MG; Park, DH; Song, GJ; Suk, K, 2015)
"Osmotic agents such as glycerol are used to treat brain edema in stroke patients."7.73Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema. ( Berger, C; Kiening, KL; Sakowitz, OW; Schwab, S, 2005)
" Pathological metabolic shift and subsequent lactic acid production are thought to play an important role in diverse painful states; however, their contribution to inflammation-driven pain is still to be comprehended."3.81Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis. ( Go, Y; Harris, RA; Jeoung, NH; Jha, MK; Kook, H; Lee, IK; Lee, MG; Park, DH; Song, GJ; Suk, K, 2015)
"Osmotic agents such as glycerol are used to treat brain edema in stroke patients."3.73Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema. ( Berger, C; Kiening, KL; Sakowitz, OW; Schwab, S, 2005)
"05) protected from lactic acidosis, glutamate buildup, and diminished HCO(3)(-) levels."3.71CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice. ( Chang, WL; Granger, DN; Huang, J; Jones, SP; Lefer, DJ; Sun, G; Suzuki, H; van der Heyde, HC; Welbourne, T; Yin, L, 2001)
"Cardiogenic shock is difficult to diagnose due to diverse presentations, overlap with other shock states (i."2.66Identifying cardiogenic shock in the emergency department. ( Daly, M; Koyfman, A; Lentz, S; Long, B, 2020)
"Myocardial edema is divided into cellular edema and interstitial edema; however, the dynamic change of cardiomyocyte edema has not been described in detail."1.51PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1. ( Dong, H; Huang, B; Liu, X; Liu, Z; Miao, H; Qiu, F; Wang, M; Yuan, Y; Zhang, H; Zhang, Z; Zhao, Q, 2019)
" Pharmacokinetic study in Wistar rats with i."1.43Lecithin and PLGA-based self-assembled nanocomposite, Lecithmer: preparation, characterization, and pharmacokinetic/pharmacodynamic evaluation. ( Fahr, A; Fariya, MK; Nagarsenker, MS; Rajawat, GS; Steiniger, F; Varghese, SE, 2016)
"5mg/mL, PF-F2NPs with cPF 1mg/mL) produced by solvent displacement technique and tested the in vitro cytotoxicity, ex vivo corneal permeation, in vivo ocular tolerance and in vivo anti-inflammatory efficacy of PF-F1NPs, PF-F2NPs, in comparison to eye drops conventional dosage form (Oftalar(®), PF 1mg/mL) and free drug solution (PF dissolved in PBS, 1."1.43In vitro, ex vivo and in vivo characterization of PLGA nanoparticles loading pranoprofen for ocular administration. ( Abrego, G; Alvarado, H; Calpena, AC; Cañadas, C; García, ML; Silva, AM; Souto, EB, 2016)
" However, the high molecular, positively charged PL is toxic in high doses, proposed as lysis of red blood cells."1.40In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats. ( Akerberg, D; Andersson, R; Isaksson, K; Posaric-Bauden, M; Tingstedt, B, 2014)
" Recent evidence shows that local/regional/systemic delayed adverse effects may appear with its use."1.35Late-onset immune-mediated adverse effects after poly-L-lactic acid injection in non-HIV patients: clinical findings and long-term follow-up. ( Alijotas-Reig, J; Garcia-Gimenez, V; Vilardell-Tarres, M, 2009)
"Triptolide (TP), which has potent immunosuppressive effects, anti-inflammatory and severe toxicity on digestive, urogenital, blood circulatory system, was used as a model drug in this study."1.33Anti-inflammatory effects of triptolide loaded poly(D,L-lactic acid) nanoparticles on adjuvant-induced arthritis in rats. ( Dong, J; Liu, M; Xu, H; Yang, X; Yang, Y, 2005)
"PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy."1.33Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006)
"This clinicopathologic case report documents an adverse effect associated with the use of a polylactic acid-based barrier in the treatment of human gingival recession defects."1.30Adverse effects associated with a bioabsorbable guided tissue regeneration device in the treatment of human gingival recession defects. A clinicopathologic case report. ( Tatakis, DN; Trombelli, L, 1999)
"Lactic acid promotes the proliferation of other mesenchymal cells as well."1.27The role of increased lactic acid concentration in neovascularizations. ( Imre, G, 1984)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.88)18.7374
1990's3 (8.82)18.2507
2000's11 (32.35)29.6817
2010's14 (41.18)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Lopez, TCC1
Malavazzi, TCDS1
Rodrigues, MFSD1
Bach, EE1
Silva, DT1
Hi, EMB1
França, CM1
Bussadori, SK1
Mesquita-Ferrari, RA1
Fernandes, KPS1
Paganini, M1
Moon, RE1
Giacon, TA1
Cialoni, D1
Martani, L1
Zucchi, L1
Garetto, G1
Talamonti, E1
Camporesi, EM1
Bosco, G1
Xi, S1
Cheng, S1
Meng, F1
Xu, B1
He, Y1
Mei, J1
Tang, M1
Daly, M1
Long, B1
Koyfman, A1
Lentz, S1
Huang, B1
Miao, H1
Yuan, Y1
Qiu, F1
Liu, X1
Liu, Z1
Zhang, H1
Zhao, Q1
Wang, M1
Dong, H1
Zhang, Z1
Jiawan, A1
Tandjung, K1
Isaksson, K1
Akerberg, D1
Posaric-Bauden, M1
Andersson, R1
Tingstedt, B1
Freitas, KC1
Hillhouse, TM1
Leitl, MD1
Negus, SS1
Jha, MK1
Song, GJ1
Lee, MG1
Jeoung, NH1
Go, Y1
Harris, RA1
Park, DH1
Kook, H1
Lee, IK1
Suk, K1
Parra, A1
Clares, B1
Rosselló, A1
Garduño-Ramírez, ML1
Abrego, G3
García, ML3
Calpena, AC3
Alvarado, H2
Souto, EB2
Guevara, B1
Bellowa, LH1
Garduño, ML1
Varghese, SE1
Fariya, MK1
Rajawat, GS1
Steiniger, F1
Fahr, A1
Nagarsenker, MS1
Cañadas, C1
Silva, AM1
Kaur, M1
Sharma, S1
Sinha, VR1
Patterson, S1
Zee, J1
Wiseman, S1
Hecker, M1
Jeong, I1
Kim, BS1
Lee, H1
Lee, KM1
Shim, I1
Kang, SK1
Yin, CS1
Hahm, DH1
Alijotas-Reig, J1
Garcia-Gimenez, V1
Vilardell-Tarres, M1
Finn, A1
Oerther, SC1
Kojic, Z1
Stojanovic, D1
Popadic, S1
Jokanovic, M1
Janackovic, D1
LaBan, MM1
Nagarajan, R1
Riutta, JC1
Loenneke, JP1
Fahs, CA1
Thiebaud, RS1
Rossow, LM1
Abe, T1
Ye, X1
Kim, D1
Bemben, MG1
Berger, C1
Sakowitz, OW1
Kiening, KL1
Schwab, S1
Liu, M1
Dong, J1
Yang, Y1
Yang, X1
Xu, H1
Huisman, TA1
Klein, A1
Werner, B1
Straube, T1
Boltshauser, E1
Bennet, L1
Roelfsema, V1
Dean, JM1
Wassink, G1
Power, GG1
Jensen, EC1
Gunn, AJ1
Ferretti, C1
Imre, G1
Tatakis, DN1
Trombelli, L1
Chang, WL1
Jones, SP1
Lefer, DJ1
Welbourne, T1
Sun, G1
Yin, L1
Suzuki, H1
Huang, J1
Granger, DN1
van der Heyde, HC1
Arnon, S1
Aviram, R1
Dolfin, T1
Regev, R1
Litmanovits, I1
Tepper, R1
Elpeleg, ON1
Sayers, SP1
Clarkson, P1
Patel, JJ1
Pearl, JM1
Laks, H1
Drinkwater, DC1
Meneshian, A1
Martin, SM1
Curzan, M1
Chang, PA1
Baum, TD1
Wang, H1
Rothschild, HR1
Gang, DL1
Fink, MP1
Wolf, C1
Groh, V1
Pehamberger, H1

Reviews

2 reviews available for lactic acid and Edema

ArticleYear
Identifying cardiogenic shock in the emergency department.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:11

    Topics: Acidosis, Lactic; Bradycardia; Confusion; Early Diagnosis; Echocardiography; Edema; Electrocardiogra

2020
Paucity of muscle metastasis in otherwise widely disseminated cancer: a conundrum.
    American journal of physical medicine & rehabilitation, 2010, Volume: 89, Issue:11

    Topics: Diagnostic Imaging; Edema; Humans; Lactic Acid; Muscle Neoplasms; Muscle, Skeletal; Neoplasm Metasta

2010

Other Studies

32 other studies available for lactic acid and Edema

ArticleYear
Histological and biochemical effects of preventive and therapeutic vascular photobiomodulation on rat muscle injury.
    Journal of biophotonics, 2022, Volume: 15, Issue:5

    Topics: Animals; Edema; Lactic Acid; Low-Level Light Therapy; Muscles; Rats

2022
Relative hypoxemia at depth during breath-hold diving investigated through arterial blood gas analysis and lung ultrasound.
    Journal of applied physiology (Bethesda, Md. : 1985), 2023, 10-01, Volume: 135, Issue:4

    Topics: Blood Gas Analysis; Carbon Dioxide; Diving; Edema; Humans; Hypoxia; Lactic Acid; Oxygen; Pulmonary A

2023
Effects of arterial blood supply and venous return on multi-territory perforator flap survival.
    Journal of plastic surgery and hand surgery, 2020, Volume: 54, Issue:3

    Topics: Angiography; Animals; Colorimetry; Edema; Epidermis; Epigastric Arteries; Glucose; Graft Survival; L

2020
PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.
    International journal of molecular medicine, 2019, Volume: 43, Issue:5

    Topics: Animals; Aquaporin 1; Cardiotonic Agents; Edema; Eye Proteins; Glucose; Glycolysis; Lactic Acid; Mal

2019
New-Onset Heart Failure.
    JAMA cardiology, 2019, 06-01, Volume: 4, Issue:6

    Topics: Acidosis; Adult; Alcoholism; Beriberi; Dyspnea; Echocardiography; Edema; Electrocardiography; Heart

2019
In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats.
    Journal of materials science. Materials in medicine, 2014, Volume: 25, Issue:5

    Topics: Animals; Edema; Hemorrhage; Injections, Intraperitoneal; Injections, Intravenous; Lactic Acid; Mater

2014
Effects of acute and sustained pain manipulations on performance in a visual-signal detection task of attention in rats.
    Drug development research, 2015, Volume: 76, Issue:4

    Topics: Animals; Attention; Behavior, Animal; Edema; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Lactic A

2015
Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Oct-21, Volume: 35, Issue:42

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Edema; Gene Expression Regulation; Hyperalgesia; I

2015
Ex vivo permeation of carprofen from nanoparticles: A comprehensive study through human, porcine and bovine skin as anti-inflammatory agent.
    International journal of pharmaceutics, 2016, Mar-30, Volume: 501, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Topical; Animals; Anti-Inflammatory Agents; beta-

2016
Biopharmaceutical profile of hydrogels containing pranoprofen-loaded PLGA nanoparticles for skin administration: In vitro, ex vivo and in vivo characterization.
    International journal of pharmaceutics, 2016, Mar-30, Volume: 501, Issue:1-2

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Drug Carriers; Drug Liberation

2016
Lecithin and PLGA-based self-assembled nanocomposite, Lecithmer: preparation, characterization, and pharmacokinetic/pharmacodynamic evaluation.
    Drug delivery and translational research, 2016, Volume: 6, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Daunorubicin; Delayed-Action Preparations; Drug Delivery Sy

2016
In vitro, ex vivo and in vivo characterization of PLGA nanoparticles loading pranoprofen for ocular administration.
    International journal of pharmaceutics, 2016, Sep-25, Volume: 511, Issue:2

    Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Cell Surv

2016
Polymer based microspheres of aceclofenac as sustained release parenterals for prolonged anti-inflammatory effect.
    Materials science & engineering. C, Materials for biological applications, 2017, Mar-01, Volume: 72

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Diclofenac; Dr

2017
Effects of chronic exposure to dietary selenomethionine on the physiological stress response in juvenile white sturgeon (Acipenser transmontanus).
    Aquatic toxicology (Amsterdam, Netherlands), 2017, Volume: 186

    Topics: Animals; Blood Glucose; Diet; Edema; Energy Metabolism; Environmental Exposure; Fishes; Gene Express

2017
Prolonged analgesic effect of PLGA-encapsulated bee venom on formalin-induced pain in rats.
    International journal of pharmaceutics, 2009, Oct-01, Volume: 380, Issue:1-2

    Topics: Acupuncture Points; Animals; Bee Venoms; Biocompatible Materials; Delayed-Action Preparations; Drug

2009
Late-onset immune-mediated adverse effects after poly-L-lactic acid injection in non-HIV patients: clinical findings and long-term follow-up.
    Dermatology (Basel, Switzerland), 2009, Volume: 219, Issue:4

    Topics: Adult; Aged; Biocompatible Materials; Cohort Studies; Cosmetic Techniques; Edema; Face; Female; Foll

2009
Can L(+)-lactate be used as a marker of experimentally induced inflammation in rats?
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59, Issue:4

    Topics: Animals; Arthritis, Experimental; Biomarkers; Carrageenan; Cyclooxygenase 2 Inhibitors; Cyclooxygena

2010
The irritative property of alpha-tricalcium phosphate to the rabbit skin.
    General physiology and biophysics, 2009, Volume: 28 Spec No

    Topics: Administration, Topical; Animals; Calcium Phosphates; Edema; Erythema; Female; Lactic Acid; Male; Oi

2009
The acute muscle swelling effects of blood flow restriction.
    Acta physiologica Hungarica, 2012, Volume: 99, Issue:4

    Topics: Acute Disease; Adult; Ankle Brachial Index; Blood Pressure; Edema; Electromyography; Exercise; Femal

2012
Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema.
    Stroke, 2005, Volume: 36, Issue:2

    Topics: Adult; Aged; Brain; Brain Edema; Drug Monitoring; Edema; Female; Glutamic Acid; Glycerol; Humans; In

2005
Anti-inflammatory effects of triptolide loaded poly(D,L-lactic acid) nanoparticles on adjuvant-induced arthritis in rats.
    Journal of ethnopharmacology, 2005, Feb-28, Volume: 97, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemistry, Pharmaceutical

2005
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion

2006
Regulation of cytochrome oxidase redox state during umbilical cord occlusion in preterm fetal sheep.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 292, Issue:4

    Topics: Animals; Blood Glucose; Brain; Carbon Dioxide; Carotid Arteries; Cerebral Cortex; Edema; Electric Im

2007
A prospective trial of poly-L-lactic/polyglycolic acid co-polymer plates and screws for internal fixation of mandibular fractures.
    International journal of oral and maxillofacial surgery, 2008, Volume: 37, Issue:3

    Topics: Absorbable Implants; Adolescent; Adult; Biocompatible Materials; Bone Plates; Bone Screws; Device Re

2008
The role of increased lactic acid concentration in neovascularizations.
    Acta morphologica Hungarica, 1984, Volume: 32, Issue:2

    Topics: Animals; Cell Division; Cell Movement; Corneal Diseases; Edema; Eye; Humans; Lactates; Lactic Acid;

1984
Adverse effects associated with a bioabsorbable guided tissue regeneration device in the treatment of human gingival recession defects. A clinicopathologic case report.
    Journal of periodontology, 1999, Volume: 70, Issue:5

    Topics: Absorbable Implants; Adult; Biocompatible Materials; Edema; Female; Foam Cells; Follow-Up Studies; F

1999
CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice.
    Infection and immunity, 2001, Volume: 69, Issue:12

    Topics: Acidosis, Lactic; Adenosine Triphosphatases; Animals; Anion Transport Proteins; Capillary Permeabili

2001
Mitochondrial DNA depletion presenting prenatally with skin edema and multisystem disease immediately after birth.
    Prenatal diagnosis, 2002, Volume: 22, Issue:1

    Topics: Consanguinity; DNA; DNA, Mitochondrial; Edema; Female; Fetal Diseases; Fetal Movement; Gestational A

2002
Metabolic response to light exercise after exercise-induced rhabdomyolysis.
    European journal of applied physiology, 2002, Volume: 86, Issue:3

    Topics: Adult; Arm; Edema; Exercise; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Muscle,

2002
Fluosol cardioplegia results in complete functional recovery: a comparison with blood cardioplegia.
    The Annals of thoracic surgery, 1992, Volume: 54, Issue:6

    Topics: Adenosine Triphosphate; Animals; Blood; Blood Chemical Analysis; Drug Evaluation, Preclinical; Edema

1992
Mesenteric oxygen metabolism, ileal mucosal hydrogen ion concentration, and tissue edema after crystalloid or colloid resuscitation in porcine endotoxic shock: comparison of Ringer's lactate and 6% hetastarch.
    Circulatory shock, 1990, Volume: 30, Issue:4

    Topics: Animals; Colloids; Edema; Escherichia coli Infections; Hydrogen-Ion Concentration; Hydroxyethyl Star

1990
[Oral leukoedema--sequela of an artifact].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1986, Volume: 37, Issue:7

    Topics: Adult; Diagnosis, Differential; Drug Combinations; Edema; Factitious Disorders; Female; Humans; Lact

1986