lactic acid has been researched along with Dyspnea in 23 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Dyspnea: Difficult or labored breathing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report 4 cases of lactic acidosis in diabetic patients usually treated with metformin." | 7.72 | [Metformin-associated lactic acidosis remains a serious complication of metformin therapy]. ( Giunti, C; Grimaud, D; Ichai, C; Levraut, J; Orban, JC, 2003) |
| "We report 4 cases of lactic acidosis in diabetic patients usually treated with metformin." | 3.72 | [Metformin-associated lactic acidosis remains a serious complication of metformin therapy]. ( Giunti, C; Grimaud, D; Ichai, C; Levraut, J; Orban, JC, 2003) |
| "Sixteen COPD patients (mean FEV1 33+/-13% predicted) underwent a 6-min walking test and performed stair-climbing (44 steps) in a randomized, cross-over design." | 2.73 | Exercise in severe COPD: is walking different from stair-climbing? ( Dreher, M; Kabitz, HJ; Prettin, S; Sonntag, F; Walterspacher, S; Windisch, W, 2008) |
| "Symptom scores of perceived breathlessness and muscle effort were recorded using Borg scales." | 2.71 | Symptoms, lactate and exercise limitation at peak cycle ergometry in adults with cystic fibrosis. ( Dodd, ME; Moorcroft, AJ; Morris, J; Webb, AK, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Villanueva Rábano, R | 1 |
| Martín-Rodríguez, F | 1 |
| López-Izquierdo, R | 1 |
| Varela, ML | 1 |
| Mota, T | 1 |
| Martins Fernandes, R | 1 |
| Soto, F | 1 |
| Chen, J | 1 |
| Zhu, YF | 1 |
| Du, ZQ | 1 |
| Li, WF | 1 |
| Zhang, MJ | 1 |
| Zhao, SD | 1 |
| Ying, JW | 1 |
| Li, Z | 1 |
| Miao, HJ | 1 |
| Jiawan, A | 1 |
| Tandjung, K | 1 |
| Suarez, N | 1 |
| Conway, N | 1 |
| Pickett, T | 1 |
| Chéhère, B | 1 |
| Bougault, V | 1 |
| Gicquello, A | 1 |
| Wallaert, B | 1 |
| Riganas, CS | 1 |
| Vrabas, IS | 1 |
| Christoulas, K | 1 |
| Mandroukas, K | 1 |
| Bailey, SJ | 1 |
| Romer, LM | 3 |
| Kelly, J | 1 |
| Wilkerson, DP | 1 |
| DiMenna, FJ | 1 |
| Jones, AM | 1 |
| Lima, Eda S | 1 |
| Cruz, CG | 1 |
| Santos, FC | 1 |
| Gomes-Neto, M | 1 |
| Bittencourt, HS | 1 |
| Reis, FJ | 1 |
| Aras, R | 1 |
| Guimarães, AC | 1 |
| Rodrigues-Junior, Ede S | 1 |
| Zurek, M | 1 |
| Schmied, C | 1 |
| Fontana, P | 1 |
| Studer, I | 1 |
| Orban, JC | 1 |
| Giunti, C | 1 |
| Levraut, J | 1 |
| Grimaud, D | 1 |
| Ichai, C | 1 |
| STRANDELL, T | 1 |
| Sabapathy, S | 1 |
| Kingsley, RA | 1 |
| Schneider, DA | 1 |
| Adams, L | 1 |
| Morris, NR | 1 |
| Moorcroft, AJ | 1 |
| Dodd, ME | 1 |
| Morris, J | 1 |
| Webb, AK | 1 |
| Haverkamp, HC | 1 |
| Amann, M | 1 |
| Lovering, AT | 1 |
| Pegelow, DF | 1 |
| Dempsey, JA | 1 |
| Dreher, M | 1 |
| Walterspacher, S | 1 |
| Sonntag, F | 1 |
| Prettin, S | 1 |
| Kabitz, HJ | 1 |
| Windisch, W | 1 |
| Taylor, BJ | 1 |
| Furui, T | 1 |
| Imai, A | 1 |
| Tamaya, T | 1 |
| Meyer, K | 1 |
| Schwaibold, M | 1 |
| Westbrook, S | 1 |
| Beneke, R | 1 |
| Hajric, R | 1 |
| Görnandt, L | 1 |
| Lehmann, M | 1 |
| Roskamm, H | 1 |
| Casaburi, R | 1 |
| Polkey, MI | 1 |
| Hawkins, P | 1 |
| Kyroussis, D | 1 |
| Ellum, SG | 1 |
| Sherwood, R | 1 |
| Moxham, J | 1 |
| Weber, KT | 1 |
| Janicki, JS | 1 |
| McElroy, PA | 1 |
| Reddy, HK | 1 |
| Volovoĭ, VL | 1 |
| Setrakian, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of the VitaBreath Device on Chest Wall Dynamic Hyperinflation and Respiratory Muscle Activation During Recovery From Exercise in Patients With Chronic Obstructive Pulmonary Disease[NCT03848819] | 14 participants (Actual) | Interventional | 2019-07-01 | Completed | |||
| Comparison of Clinical and Physiological Response Among Three Modalities of Exercise Training in COPD With Chronic Respiratory Failure (CRF)[NCT04201548] | 60 participants (Anticipated) | Interventional | 2019-08-28 | Recruiting | |||
| Effectiveness of Chest Compressions Under Mild Hypoxia: Should Rescuers Breathe Supplemental Oxygen on Commercial Flights?[NCT04072484] | 19 participants (Actual) | Interventional | 2019-08-16 | Terminated (stopped due to Research at the University of Chicago was halted in March 2020.) | |||
| Regulation of Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease: A Mechanistic Approach[NCT01398943] | 60 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Brachial artery FMD induced by reactive hyperemia will be used to assess vascular endothelial function at baseline and several hours after each experimental intervention. (NCT01398943)
Timeframe: Post FMD was taken approximately 110 min after baseline
| Intervention | percentage of change in FMD (Mean) | |
|---|---|---|
| Placebo | AOC Treatment | |
| All Controls | 6.7 | 6.9 |
| All COPD Patients | 3.1 | 4.7 |
A measure of vascular stiffness at baseline and several hours after each experimental intervention. (NCT01398943)
Timeframe: Post PWV was taken approximately 90 min after baseline
| Intervention | m/sec (Mean) | |
|---|---|---|
| Placebo | AOC Treatment | |
| All Controls | 11 | 10 |
| All COPD Patients | 14 | 11 |
2 reviews available for lactic acid and Dyspnea
| Article | Year |
|---|---|
Skeletal muscle function in COPD.
Topics: Anabolic Agents; Biomechanical Phenomena; Dyspnea; Exercise Therapy; Humans; Lactic Acid; Lung Disea | 2000 |
Concepts and applications of cardiopulmonary exercise testing.
Topics: Dyspnea; Exercise Test; Heart Failure; Humans; Lactates; Lactic Acid; Physical Exertion; Pulmonary G | 1988 |
6 trials available for lactic acid and Dyspnea
| Article | Year |
|---|---|
Inspiratory muscle training enhances pulmonary O(2) uptake kinetics and high-intensity exercise tolerance in humans.
Topics: Adaptation, Physiological; Adult; Biomarkers; Breathing Exercises; Dyspnea; Exercise Test; Exercise | 2010 |
Effect of ventilatory support on functional capacity in patients with heart failure: a pilot study.
Topics: Adult; Blood Pressure; Dyspnea; Exercise Test; Female; Heart Failure; Humans; Lactic Acid; Male; Mid | 2011 |
Symptoms, lactate and exercise limitation at peak cycle ergometry in adults with cystic fibrosis.
Topics: Adult; Cystic Fibrosis; Dyspnea; Exercise Test; Exercise Tolerance; Female; Humans; Lactic Acid; Lun | 2005 |
Exercise in severe COPD: is walking different from stair-climbing?
Topics: Aged; Carbon Dioxide; Cross-Over Studies; Dyspnea; Exercise; Exercise Test; Female; Forced Expirator | 2008 |
Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure.
Topics: Chronic Disease; Dyspnea; Exercise; Fatigue; Female; Heart Failure; Heart Rate; Hemodynamics; Humans | 1996 |
Inspiratory pressure support prolongs exercise induced lactataemia in severe COPD.
Topics: Acidosis, Respiratory; Aged; Dyspnea; Exercise Therapy; Forced Expiratory Volume; Humans; Hydrogen-I | 2000 |
15 other studies available for lactic acid and Dyspnea
| Article | Year |
|---|---|
National Early Warning Score 2 Lactate (NEWS2-L) in Predicting Early Clinical Deterioration in Patients with Dyspnoea in Prehospital Care.
Topics: Clinical Deterioration; Dyspnea; Early Warning Score; Emergency Medical Services; Hospital Mortality | 2021 |
Peeking at the right heart at the right moment: a giant thrombus in transit.
Topics: Acute-On-Chronic Liver Failure; Anticoagulants; Cardiomyopathy, Dilated; Dyspnea; Echocardiography; | 2020 |
Predictors of mechanical ventilation for COVID-19: combined data from three designated hospitals.
Topics: Aged; Aged, 80 and over; APACHE; Area Under Curve; Blood Urea Nitrogen; COVID-19; Creatine Kinase; C | 2020 |
New-Onset Heart Failure.
Topics: Acidosis; Adult; Alcoholism; Beriberi; Dyspnea; Echocardiography; Edema; Electrocardiography; Heart | 2019 |
Panic-related hyperventilation resulting in hypophosphataemia and a high lactate.
Topics: Adult; Chest Pain; Dyspnea; Female; Humans; Hyperventilation; Hypophosphatemia; Lactic Acid; Panic; | 2013 |
Cardiorespiratory Response to Different Exercise Tests in Interstitial Lung Disease.
Topics: Dyspnea; Exercise Test; Exercise Tolerance; Female; Heart Rate; Humans; Lactic Acid; Leg; Lung Disea | 2016 |
Specific inspiratory muscle training does not improve performance or VO2max levels in well trained rowers.
Topics: Adaptation, Physiological; Adult; Dyspnea; Exercise Tolerance; Female; Humans; Inspiratory Capacity; | 2008 |
[Clinical assessment of exertion intolerance and stress dyspnea with spiroergometry].
Topics: Cardiovascular Deconditioning; Coronary Artery Bypass; Diagnosis, Differential; Dyspnea; Ergometry; | 2012 |
[Metformin-associated lactic acidosis remains a serious complication of metformin therapy].
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Diabetes Complications; Diabetes Mellitus, Type | 2003 |
HEART RATE, ARTERIAL LACTATE CONCENTRATION AND OXYGEN UPTAKE DURING EXERCISE IN OLD MEN COMPARED WITH YOUNG MEN.
Topics: Aging; Blood Chemical Analysis; Dyspnea; Exercise Test; Fatigue; Geriatrics; Heart; Heart Rate; Huma | 1964 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Topics: Aged; Dyspnea; Exercise; Female; Forced Expiratory Volume; Humans; Lactic Acid; Male; Oxygen Consump | 2004 |
Effect of acute severe hypoxia on peripheral fatigue and endurance capacity in healthy humans.
Topics: Adult; Dyspnea; Electromagnetic Fields; Exercise; Exercise Test; Femoral Nerve; Humans; Hypoxia; Lac | 2007 |
Effect of expiratory muscle fatigue on exercise tolerance and locomotor muscle fatigue in healthy humans.
Topics: Abdominal Muscles; Adult; Dyspnea; Electromagnetic Fields; Electromyography; Electrophysiology; Exer | 2008 |
Successful outcome of pregnancy complicated with thyroidectomy-induced hypoparathyroidism and sudden dyspnea. A case report.
Topics: Adenocarcinoma, Papillary; Adult; Calcium; Calcium Gluconate; Cesarean Section; Dyspnea; Female; Hum | 1993 |
[Concept of the anaerobic threshold and its clinical significance].
Topics: Acidosis; Cardiac Rehabilitation; Cardiovascular Diseases; Diagnosis, Differential; Dyspnea; Exercis | 1986 |