lactic acid has been researched along with Discitis in 2 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Discitis: Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To prepare the vancomycin hydrochloride (VA)-loaded poly lactic acid-glycolic acid (PLGA) copolymer microsphere by the multiple emulsion method and evaluate its therapeutic effects on infective discitis." | 7.77 | Intra-discal vancomycin-loaded PLGA microsphere injection for MRSA discitis: an experimental study. ( Liu, F; Liu, J; Ni, B; Wang, F; Zhu, YZ; Zhu, Z, 2011) |
| "Polylactic acid (PLA) patch has proper steric configuration, sufficient mechanic strength, and flexibility, to investigate the blocking effect on the intra-discal inflammation after annulus puncture sticked by medical glue so as to seal the pinhole left after annulus puncture." | 7.76 | [A study on blocking effect of polylactic acid patch on intra-discal inflammation after annulus puncture]. ( Feng, G; Gong, Q; Huang, X; Li, T; Liu, H; Liu, L; Liu, X; Shi, R; Song, Y; Zhang, W; Zhao, X, 2010) |
| "To prepare the vancomycin hydrochloride (VA)-loaded poly lactic acid-glycolic acid (PLGA) copolymer microsphere by the multiple emulsion method and evaluate its therapeutic effects on infective discitis." | 3.77 | Intra-discal vancomycin-loaded PLGA microsphere injection for MRSA discitis: an experimental study. ( Liu, F; Liu, J; Ni, B; Wang, F; Zhu, YZ; Zhu, Z, 2011) |
| "Polylactic acid (PLA) patch has proper steric configuration, sufficient mechanic strength, and flexibility, to investigate the blocking effect on the intra-discal inflammation after annulus puncture sticked by medical glue so as to seal the pinhole left after annulus puncture." | 3.76 | [A study on blocking effect of polylactic acid patch on intra-discal inflammation after annulus puncture]. ( Feng, G; Gong, Q; Huang, X; Li, T; Liu, H; Liu, L; Liu, X; Shi, R; Song, Y; Zhang, W; Zhao, X, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, F | 1 |
| Ni, B | 1 |
| Zhu, Z | 1 |
| Liu, F | 1 |
| Zhu, YZ | 1 |
| Liu, J | 1 |
| Liu, X | 1 |
| Liu, H | 1 |
| Zhao, X | 1 |
| Shi, R | 1 |
| Huang, X | 1 |
| Zhang, W | 1 |
| Feng, G | 1 |
| Song, Y | 1 |
| Li, T | 1 |
| Gong, Q | 1 |
| Liu, L | 1 |
2 other studies available for lactic acid and Discitis
| Article | Year |
|---|---|
Intra-discal vancomycin-loaded PLGA microsphere injection for MRSA discitis: an experimental study.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Discitis; Lactic Acid; Methicillin-Resistan | 2011 |
[A study on blocking effect of polylactic acid patch on intra-discal inflammation after annulus puncture].
Topics: Animals; Discitis; Disease Models, Animal; Female; Inflammation; Interleukin-1beta; Intervertebral D | 2010 |