lactic acid has been researched along with Diathesis in 23 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxidative phosphorylation of isolated rat skeletal muscle mitochondria after exposure to lactic acidosis in either phosphorylating or nonphosphorylating states has been evaluated." | 7.70 | Actively phosphorylating mitochondria are more resistant to lactic acidosis than inactive mitochondria. ( Sahlin, K; Tonkonogi, M, 1999) |
| "Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 5.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
| "Oxidative phosphorylation of isolated rat skeletal muscle mitochondria after exposure to lactic acidosis in either phosphorylating or nonphosphorylating states has been evaluated." | 3.70 | Actively phosphorylating mitochondria are more resistant to lactic acidosis than inactive mitochondria. ( Sahlin, K; Tonkonogi, M, 1999) |
| "Using cultured mesenchymal and cancer cells, as well as mouse allograft models, we provide evidence that extracellular lactate can be utilized by fibroblasts to maintain tricarboxylic acid (TCA) cycle anaplerosis and non-essential amino acid biosynthesis through PC activity." | 1.62 | Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. ( Cai, X; Cimino, FV; King, B; Pavlova, NN; Schwörer, S; Sizemore, GM; Thompson, CB, 2021) |
| "SLC1A3 was found to be overexpressed in gastric cancer, and this overexpression was associated with poor prognosis." | 1.56 | SLC1A3 promotes gastric cancer progression via the PI3K/AKT signalling pathway. ( Awaleh Moumin, F; Cai, J; Chen, J; Chen, X; Jia, L; Xu, L, 2020) |
| "Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 1.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
| "Glycogen levels were significantly lower in both rhesus (median=0." | 1.38 | A comparison of lower genital tract glycogen and lactic acid levels in women and macaques: implications for HIV and SIV susceptibility. ( Gilbert, D; Kendrick, SR; Mirmonsef, P; Spear, GT; Veazey, RS; Wang, J, 2012) |
| " MH susceptibility leads to a leftward shift of the dose-response curve for IM lactate after local injection of halothane and caffeine." | 1.33 | The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. ( Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (21.74) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 6 (26.09) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, ZH | 1 |
| Peng, WB | 1 |
| Zhang, P | 1 |
| Yang, XP | 1 |
| Zhou, Q | 1 |
| Schwörer, S | 1 |
| Pavlova, NN | 1 |
| Cimino, FV | 1 |
| King, B | 1 |
| Cai, X | 1 |
| Sizemore, GM | 1 |
| Thompson, CB | 1 |
| Manosalva, C | 1 |
| Quiroga, J | 1 |
| Hidalgo, AI | 1 |
| Alarcón, P | 1 |
| Anseoleaga, N | 1 |
| Hidalgo, MA | 1 |
| Burgos, RA | 1 |
| Xu, J | 1 |
| Jakher, Y | 1 |
| Ahrens-Nicklas, RC | 1 |
| Xu, L | 1 |
| Chen, J | 1 |
| Jia, L | 1 |
| Chen, X | 1 |
| Awaleh Moumin, F | 1 |
| Cai, J | 1 |
| Martiñón-Gutiérrez, G | 1 |
| Luna-Castro, M | 1 |
| Hernández-Muñoz, R | 1 |
| Karnib, N | 1 |
| El-Ghandour, R | 1 |
| El Hayek, L | 1 |
| Nasrallah, P | 1 |
| Khalifeh, M | 1 |
| Barmo, N | 1 |
| Jabre, V | 1 |
| Ibrahim, P | 1 |
| Bilen, M | 1 |
| Stephan, JS | 1 |
| Holson, EB | 1 |
| Ratan, RR | 1 |
| Sleiman, SF | 1 |
| Faulhaber, M | 1 |
| Wille, M | 1 |
| Gatterer, H | 1 |
| Heinrich, D | 1 |
| Burtscher, M | 1 |
| Ma, X | 1 |
| Deng, J | 1 |
| Cao, N | 1 |
| Guo, Z | 1 |
| Zheng, Y | 1 |
| Geng, S | 1 |
| Meng, M | 1 |
| Lin, H | 1 |
| Duan, Y | 1 |
| Du, G | 1 |
| Mirmonsef, P | 1 |
| Gilbert, D | 1 |
| Veazey, RS | 1 |
| Wang, J | 1 |
| Kendrick, SR | 1 |
| Spear, GT | 1 |
| Johannsen, S | 1 |
| Berberich, C | 1 |
| Metterlein, T | 1 |
| Roth, C | 1 |
| Reiners, K | 1 |
| Roewer, N | 2 |
| Schuster, F | 2 |
| Ramos, JJ | 1 |
| Marca, C | 1 |
| Loste, A | 1 |
| García de Jalón, JA | 1 |
| Fernández, A | 1 |
| Cubel, T | 1 |
| Schöll, H | 1 |
| Hager, M | 1 |
| Müller, R | 1 |
| Anetseder, M | 1 |
| Podesser, BK | 1 |
| Jain, M | 1 |
| Ngoy, S | 1 |
| Apstein, CS | 1 |
| Eberli, FR | 1 |
| Nelson, TE | 1 |
| Flewellen, EH | 1 |
| Gloyna, DF | 1 |
| Coverly, J | 1 |
| Peters, L | 1 |
| Whittle, E | 1 |
| Basketter, DA | 1 |
| Tonkonogi, M | 1 |
| Sahlin, K | 1 |
| Gao, XJ | 1 |
| Deng, DM | 1 |
| Geng, QM | 1 |
| Wedel, DJ | 1 |
| Iaizzo, PA | 1 |
| Milde, JH | 1 |
| Yoshida, S | 1 |
| Gershwin, ME | 1 |
| Keen, CL | 1 |
| Donald, JM | 1 |
| Golub, MS | 1 |
| Ording, H | 2 |
| Fonsmark, L | 1 |
| Nielsen, VG | 1 |
| Cozzi, PJ | 1 |
| Lyon, RT | 1 |
| Davis, HR | 1 |
| Sylora, J | 1 |
| Glagov, S | 1 |
| Zarins, CK | 1 |
3 reviews available for lactic acid and Diathesis
| Article | Year |
|---|---|
Lactate in the tumour microenvironment: From immune modulation to therapy.
Topics: Animals; Biological Transport; Biomarkers; Disease Management; Disease Susceptibility; Energy Metabo | 2021 |
Role of Lactate in Inflammatory Processes: Friend or Foe.
Topics: Animals; Biological Transport; Biomarkers; Cytokines; Disease Susceptibility; Energy Metabolism; Hum | 2021 |
Brain Branched-Chain Amino Acids in Maple Syrup Urine Disease: Implications for Neurological Disorders.
Topics: Amino Acids, Branched-Chain; Aspartic Acid; Brain; Central Nervous System; Disease Susceptibility; G | 2020 |
20 other studies available for lactic acid and Diathesis
| Article | Year |
|---|---|
Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment.
Topics: Animals; Cancer-Associated Fibroblasts; Cell Line; Citric Acid Cycle; Collagen; Disease Susceptibili | 2021 |
SLC1A3 promotes gastric cancer progression via the PI3K/AKT signalling pathway.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Survival; Cell Transf | 2020 |
Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Electromagnetic Fields; Energy | 2021 |
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases.
Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Behavior, Animal; Benzamides; Depressio | 2019 |
Resting arterial oxygen saturation and breathing frequency as predictors for acute mountain sickness development: a prospective cohort study.
Topics: Acute Disease; Adult; Altitude Sickness; Atmosphere Exposure Chambers; Cohort Studies; Disease Susce | 2014 |
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Diseas | 2016 |
A comparison of lower genital tract glycogen and lactic acid levels in women and macaques: implications for HIV and SIV susceptibility.
Topics: Animals; Disease Susceptibility; Female; Glycogen; HIV Antibodies; HIV Infections; HIV-1; Humans; La | 2012 |
Screening test for malignant hyperthermia in patients with persistent hyperCKemia: a pilot study.
Topics: Adult; Creatine Kinase; Disease Susceptibility; Female; Humans; Lactic Acid; Male; Malignant Hyperth | 2013 |
Biochemical changes in apparently normal sheep from flocks affected by polioencephalomalacia.
Topics: Animals; Disease Susceptibility; Encephalomalacia; Feces; Female; Hydrolases; Lactic Acid; Male; Pre | 2003 |
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Re | 2006 |
Unveiling gender differences in demand ischemia: a study in a rat model of genetic hypertension.
Topics: Animals; Coronary Circulation; Diastole; Disease Models, Animal; Disease Susceptibility; Female; Hyp | 2007 |
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; | 1983 |
Susceptibility to skin stinging, non-immunologic contact urticaria and acute skin irritation; is there a relationship?
Topics: Acrolein; Acute Disease; Administration, Topical; Adult; Anti-Inflammatory Agents; Antimutagenic Age | 1998 |
Actively phosphorylating mitochondria are more resistant to lactic acidosis than inactive mitochondria.
Topics: Acidosis, Lactic; Adenosine Diphosphate; Animals; Disease Susceptibility; Hydrogen-Ion Concentration | 1999 |
A study of oral health condition in individuals with no oral hygiene and its association with plaque acidogenesis.
Topics: Acids, Acyclic; Bacteria; Carboxylic Acids; Dental Calculus; Dental Caries; Dental Caries Susceptibi | 2000 |
Desflurane is a trigger of malignant hyperthermia in susceptible swine.
Topics: Anesthesia, Inhalation; Animals; Blood; Body Temperature; Carbon Dioxide; Desflurane; Disease Suscep | 1991 |
The influence of aluminum on resistance to listeria monocytogenes in Swiss-Webster mice.
Topics: Aluminum; Animals; Diet; Disease Susceptibility; Erythrocyte Indices; Female; Immunity, Innate; Inje | 1989 |
Use of vecuronium and doxapram in patients susceptible to malignant hyperthermia.
Topics: Adult; Anesthesia, General; Body Temperature; Carbon Dioxide; Disease Susceptibility; Doxapram; Huma | 1988 |
Atracurium and its antagonism by neostigmine (plus glycopyrrolate) in patients susceptible to malignant hyperthermia.
Topics: Adult; Atracurium; Body Temperature; Carbon Dioxide; Disease Susceptibility; Glycopyrrolate; Humans; | 1986 |
Aortic wall metabolism in relation to susceptibility and resistance to experimental atherosclerosis.
Topics: Animals; Aorta; Aortic Coarctation; Aortic Diseases; Arteriosclerosis; Blood Pressure; Deoxyglucose; | 1988 |