lactic acid has been researched along with Diarrhea in 46 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of Saccharomyces boulardii and lactic acid producing probiotics in addition to usual treatment regimen to cure diarrhea among children (6 months to 5 years of age)." | 9.27 | Clinical Efficacy Comparison of Saccharomyces Boulardii and Lactic Acid as Probiotics in Acute Pediatric Diarrhea. ( Asmat, R; Asmat, S; Asmat, TM; Bakhat, HFSG; Shaukat, F, 2018) |
| " During the past decade, however, evidence has accumulated that d-lactic acidosis is a more common occurrence in calves with neonatal diarrhoea." | 8.85 | D-Lactic acidosis in calves. ( Lorenz, I, 2009) |
| "We present a case series comparing lactic acid levels in children with suspected and confirmed intussusception." | 7.85 | Comparison of Lactic Acid Levels in Children with Suspected and Confirmed Intussusception. ( Ishimine, P; Tamas, V, 2017) |
| " During the past decade, however, evidence has accumulated that d-lactic acidosis is a more common occurrence in calves with neonatal diarrhoea." | 4.85 | D-Lactic acidosis in calves. ( Lorenz, I, 2009) |
| "We present a case series comparing lactic acid levels in children with suspected and confirmed intussusception." | 3.85 | Comparison of Lactic Acid Levels in Children with Suspected and Confirmed Intussusception. ( Ishimine, P; Tamas, V, 2017) |
| " Calves that stand insecurely and are not able to correct their position if pushed require higher doses of sodium bicarbonate, if there is clinical evidence of a marked D-lactic acidosis." | 3.78 | Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea. ( Feist, M; Lorch, A; Lorenz, I; Sauter-Louis, C; Trefz, FM, 2012) |
| "The frequency of diarrhea was higher in LPS group than in LPS + Lianshu group and LPS + berberine group (36." | 3.75 | Effect of Lianshu preparation on lipopolysaccharide-induced diarrhea in rats. ( Guo, CY; Liu, H; Liu, J; Wan, R; Wang, XP; Xia, YJ; Xu, XF; Yan, DX; Yan, QL; Yang, WJ, 2009) |
| " In conclusion, no thiamine deficiency was noted in patients with normal anion gap, but thiamine deficiency was not uncommon in patients with a wide anion gap, regardless of lactic acidosis." | 3.74 | A preliminary study of thiamine status in northeastern Thai children with acute diarrhea. ( Boonsiri, P; Panthongviriyakul, C; Tangrassameeprasert, R; Yongvanit, P, 2007) |
| "Methotrexate (MTX) chemotherapy is often accompanied by side effects such as gastrointestinal ulceration and diarrhea." | 3.73 | Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats. ( Celik, A; Eralp, A; Yüncü, M, 2006) |
| "To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 normals." | 3.67 | Organic anions and the diarrhea of inflammatory bowel disease. ( Breuer, RI; Gnaedinger, A; Hauck, W; Vernia, P, 1988) |
| "None required second cycle of dehydration correction." | 2.84 | Randomized Double-blind Trial of Ringer Lactate Versus Normal Saline in Pediatric Acute Severe Diarrheal Dehydration. ( Kartha, GB; Mahadevan, S; Rameshkumar, R, 2017) |
| "PPL could effectively improve the daily weight gain, fecal score, and dehydration score, and the dosage of 0." | 1.91 | Blood metabolomics reveals the therapeutic effect of Pueraria polysaccharide on calf diarrhea. ( Cao, S; Deng, JL; Peng, G; Shen, L; Shen, Y; Su, Z; Wu, X; You, L; Yu, S; Zhang, Y; Zhong, Z; Zhu, Y; Zong, X, 2023) |
| "Hyperkalemia is a clinically important electrolyte imbalance in neonatal diarrheic calves that has previously been associated with skeletal muscle weakness and life-threatening cardiac arrhythmias." | 1.39 | Hyperkalemia in neonatal diarrheic calves depends on the degree of dehydration and the cause of the metabolic acidosis but does not require the presence of acidemia. ( Constable, PD; Knubben-Schweizer, G; Lorch, A; Lorenz, I; Sauter-Louis, C; Trefz, FM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (15.22) | 18.7374 |
| 1990's | 8 (17.39) | 18.2507 |
| 2000's | 11 (23.91) | 29.6817 |
| 2010's | 16 (34.78) | 24.3611 |
| 2020's | 4 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, L | 1 |
| Shen, Y | 1 |
| You, L | 1 |
| Zhang, Y | 2 |
| Su, Z | 1 |
| Peng, G | 1 |
| Deng, JL | 1 |
| Zhong, Z | 1 |
| Yu, S | 1 |
| Zong, X | 1 |
| Wu, X | 1 |
| Zhu, Y | 2 |
| Cao, S | 1 |
| Blake, AB | 1 |
| Guard, BC | 1 |
| Honneffer, JB | 1 |
| Lidbury, JA | 1 |
| Steiner, JM | 1 |
| Suchodolski, JS | 1 |
| Vakili, B | 1 |
| Fateh, A | 1 |
| Asadzadeh Aghdaei, H | 1 |
| Sotoodehnejadnematalahi, F | 1 |
| Siadat, SD | 1 |
| Parente, CS | 1 |
| Sandland-Taylor, LE | 1 |
| Akhtar, W | 1 |
| Chen, YM | 1 |
| Limaye, A | 1 |
| Chang, HW | 1 |
| Liu, JR | 1 |
| Kartha, GB | 1 |
| Rameshkumar, R | 1 |
| Mahadevan, S | 1 |
| Xu, X | 1 |
| Liu, L | 1 |
| Yao, S | 1 |
| Gomez, DE | 1 |
| Lofstedt, J | 1 |
| Arroyo, LG | 1 |
| Wichtel, M | 1 |
| Muirhead, T | 1 |
| Stämpfli, H | 1 |
| McClure, JT | 1 |
| Tamas, V | 1 |
| Ishimine, P | 1 |
| Asmat, S | 1 |
| Shaukat, F | 1 |
| Asmat, R | 1 |
| Bakhat, HFSG | 1 |
| Asmat, TM | 1 |
| Durkalec-Michalski, K | 1 |
| Zawieja, EE | 1 |
| Podgórski, T | 1 |
| Zawieja, BE | 1 |
| Michałowska, P | 1 |
| Łoniewski, I | 1 |
| Jeszka, J | 1 |
| Shi, Q | 1 |
| Wang, J | 2 |
| Yang, H | 1 |
| Zhu, W | 1 |
| Schwedhelm, L | 1 |
| Kirchner, D | 1 |
| Klaus, B | 1 |
| Bachmann, L | 1 |
| Bolla, PA | 1 |
| Carasi, P | 1 |
| Bolla, Mde L | 1 |
| De Antoni, GL | 1 |
| Serradell, Mde L | 1 |
| Trefz, FM | 2 |
| Constable, PD | 1 |
| Sauter-Louis, C | 2 |
| Lorch, A | 2 |
| Knubben-Schweizer, G | 1 |
| Lorenz, I | 5 |
| Kilpinen, S | 1 |
| Rantala, M | 1 |
| Spillmann, T | 1 |
| Björkroth, J | 1 |
| Westermarck, E | 1 |
| Sareban, M | 1 |
| Zügel, D | 1 |
| Koehler, K | 1 |
| Hartveg, P | 1 |
| Zügel, M | 1 |
| Schumann, U | 1 |
| Steinacker, JM | 1 |
| Treff, G | 1 |
| Hynönen, U | 1 |
| Rasinkangas, P | 1 |
| Satokari, R | 1 |
| Paulin, L | 1 |
| de Vos, WM | 1 |
| Pietilä, TE | 1 |
| Kant, R | 1 |
| Palva, A | 1 |
| Boonsiri, P | 1 |
| Tangrassameeprasert, R | 1 |
| Panthongviriyakul, C | 1 |
| Yongvanit, P | 1 |
| Sato, H | 1 |
| Liu, J | 1 |
| Wan, R | 1 |
| Xu, XF | 1 |
| Wang, XP | 1 |
| Yang, WJ | 1 |
| Xia, YJ | 1 |
| Liu, H | 1 |
| Yan, QL | 1 |
| Yan, DX | 1 |
| Guo, CY | 1 |
| Kumari, A | 1 |
| Catanzaro, R | 1 |
| Marotta, F | 1 |
| Feist, M | 1 |
| CORTESI, M | 1 |
| CEVINI, G | 1 |
| Yüncü, M | 1 |
| Eralp, A | 1 |
| Celik, A | 1 |
| Wultańska, D | 1 |
| Pituch, H | 1 |
| Obuch-Woszczatyński, P | 1 |
| Meisel-Mikołajczyk, F | 1 |
| Luczak, M | 1 |
| Etheridge, RD | 1 |
| Seerley, RW | 1 |
| Huber, TL | 1 |
| Leyer, GJ | 1 |
| Wang, LL | 1 |
| Johnson, EA | 1 |
| Flourié, B | 2 |
| Briet, F | 1 |
| Florent, C | 1 |
| Pellier, P | 1 |
| Maurel, M | 1 |
| Rambaud, JC | 1 |
| Hove, H | 1 |
| Krishnan, S | 1 |
| Rajan, DP | 1 |
| Ramakrishna, BS | 1 |
| Kingamkono, R | 1 |
| Sjögren, E | 1 |
| Svanberg, U | 1 |
| Grove-White, DH | 1 |
| White, DG | 1 |
| Bomba, A | 1 |
| Nemcová, R | 1 |
| Gancarcíková, S | 1 |
| Herich, R | 1 |
| Kastel, R | 1 |
| Cambie, C | 1 |
| Clerbaux, T | 1 |
| Moreaux, B | 1 |
| Detry, B | 1 |
| Beerens, D | 1 |
| Frans, A | 1 |
| Gustin, P | 1 |
| Omole, OO | 1 |
| Nappert, G | 1 |
| Naylor, JM | 2 |
| Zello, GA | 1 |
| Tsukahara, T | 1 |
| Ushida, K | 1 |
| Clausen, MR | 1 |
| Bonnén, H | 1 |
| Tvede, M | 1 |
| Mortensen, PB | 1 |
| Boivin, M | 1 |
| Rizza, RA | 1 |
| Go, VL | 1 |
| DiMagno, EP | 1 |
| Kasari, TR | 1 |
| Vernia, P | 2 |
| Gnaedinger, A | 1 |
| Hauck, W | 1 |
| Breuer, RI | 1 |
| Latella, G | 1 |
| Magliocca, FM | 1 |
| Caprilli, R | 1 |
| Uramoto, S | 1 |
| Kagota, K | 1 |
| Niiyama, M | 1 |
| Namioka, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of Kefir[NCT02707198] | Phase 2 | 2 participants (Actual) | Interventional | 2015-11-30 | Terminated (stopped due to Study was not feasible to complete at study site) | ||
| Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Adults on Antibiotics[NCT00848003] | Phase 1 | 40 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lactic acid and Diarrhea
| Article | Year |
|---|---|
Clinical importance of lactic acid bacteria: a short review.
Topics: Cardiovascular Diseases; Diarrhea; Humans; Lactic Acid; Lactobacillus; Neoplasms; Probiotics | 2011 |
D-Lactic acidosis in calves.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Newborn; Blood Gas Analysis; Cattle; Catt | 2009 |
Lactate and short chain fatty acid production in the human colon: implications for D-lactic acidosis, short-bowel syndrome, antibiotic-associated diarrhoea, colonic cancer, and inflammatory bowel disease.
Topics: Acidosis, Lactic; Animals; Colon; Colonic Neoplasms; Diarrhea; Fatty Acids, Volatile; Humans; Intest | 1998 |
6 trials available for lactic acid and Diarrhea
| Article | Year |
|---|---|
Randomized Double-blind Trial of Ringer Lactate Versus Normal Saline in Pediatric Acute Severe Diarrheal Dehydration.
Topics: Administration, Intravenous; Child, Preschool; Cost-Benefit Analysis; Creatinine; Dehydration; Diarr | 2017 |
Clinical Efficacy Comparison of Saccharomyces Boulardii and Lactic Acid as Probiotics in Acute Pediatric Diarrhea.
Topics: Anti-Bacterial Agents; Child, Preschool; Diarrhea; Dietary Supplements; Female; Humans; Infant; Lact | 2018 |
The Effect of a New Sodium Bicarbonate Loading Regimen on Anaerobic Capacity and Wrestling Performance.
Topics: Adolescent; Adult; Anaerobic Threshold; Athletes; Athletic Performance; Blood Glucose; Diarrhea; Die | 2018 |
Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chronic Disease; Diarrhea; Dogs; Double-Blind | 2015 |
Carbohydrate Intake in Form of Gel Is Associated With Increased Gastrointestinal Distress but Not With Performance Differences Compared With Liquid Carbohydrate Ingestion During Simulated Long-Distance Triathlon.
Topics: Adult; Athletes; Athletic Performance; Beverages; Bicycling; Blood Glucose; Colic; Cross-Over Studie | 2016 |
Enteropathogenic bacteria in faecal swabs of young children fed on lactic acid-fermented cereal gruels.
Topics: Beverages; Breast Feeding; Child Nutritional Physiological Phenomena; Child, Preschool; Diarrhea; Di | 1999 |
37 other studies available for lactic acid and Diarrhea
| Article | Year |
|---|---|
Blood metabolomics reveals the therapeutic effect of Pueraria polysaccharide on calf diarrhea.
Topics: Animals; Anti-Bacterial Agents; Cattle; Diarrhea; Lactic Acid; Metabolomics; Pueraria | 2023 |
Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease.
Topics: Animals; Bile Acids and Salts; Diarrhea; Dog Diseases; Dogs; Dysbiosis; Feces; Female; Gastrointesti | 2019 |
Characterization of Gut Microbiota in Hospitalized Patients with Clostridioides difficile Infection.
Topics: Adolescent; Adult; Bacteria; Butyrates; Case-Control Studies; Clostridioides difficile; Clostridium | 2020 |
Diagnostic challenge: an atypical presentation of infective endocarditis.
Topics: Bacteremia; Blood Culture; C-Reactive Protein; Diagnosis, Differential; Diarrhea; Dysentery; Early W | 2021 |
Screening of Lactic Acid Bacterial Strains with Antiviral Activity Against Porcine Epidemic Diarrhea.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Coronavirus Infections; Diarrhea; Dysentery; Interl | 2022 |
[Visceral sensitivity, gut barrier function and autonomic nerve function in patients with diarrhea-predominant irritable bowel syndrome].
Topics: Amine Oxidase (Copper-Containing); Autonomic Pathways; Biomarkers; Case-Control Studies; China; Diar | 2017 |
Association of unmeasured strong ions with outcome of hospitalized beef and dairy diarrheic calves.
Topics: Acid-Base Equilibrium; Animals; Cattle; Cattle Diseases; Diarrhea; Ions; Lactic Acid | 2017 |
Comparison of Lactic Acid Levels in Children with Suspected and Confirmed Intussusception.
Topics: Abdominal Pain; Child, Preschool; Diarrhea; Female; Fever; Humans; Infant; Intussusception; Ischemia | 2017 |
Protein restriction and succedent realimentation affecting ileal morphology, ileal microbial composition and metabolites in weaned piglets.
Topics: Ammonia; Animal Feed; Animals; Diarrhea; Diet; Diet, Protein-Restricted; Dietary Proteins; Digestion | 2019 |
Experimentally induced hyperchloremic and DL-lactic acidosis in calves: an attempt to study the effects of oral rehydration on acid-base status.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Newborn; Calcium; Carbon Dioxide; Cattle; | 2013 |
Protective effect of a mixture of kefir-isolated lactic acid bacteria and yeasts in a hamster model of Clostridium difficile infection.
Topics: Administration, Oral; Animals; Bacterial Toxins; Cecum; Clostridioides difficile; Cricetinae; Cultur | 2013 |
Hyperkalemia in neonatal diarrheic calves depends on the degree of dehydration and the cause of the metabolic acidosis but does not require the presence of acidemia.
Topics: Acidosis; Animals; Cattle; Cattle Diseases; Creatinine; Dehydration; Diarrhea; Hydrogen-Ion Concentr | 2013 |
Isolation and whole genome sequencing of a Ruminococcus-like bacterium, associated with irritable bowel syndrome.
Topics: Acetic Acid; Bacteria, Anaerobic; Base Composition; Base Sequence; Diarrhea; Ethanol; Fatty Acids; F | 2016 |
A preliminary study of thiamine status in northeastern Thai children with acute diarrhea.
Topics: Acidosis, Lactic; Acute Disease; Case-Control Studies; Child; Child, Preschool; Diarrhea; Female; Hu | 2007 |
Increased fecal lactate and decreased volatile fatty acid (VFA), particularly n-butyrate concentrations in diarrheic young calves.
Topics: Ammonia; Animals; Butyrates; Cattle; Cattle Diseases; Diarrhea; Feces; Hydrogen-Ion Concentration; L | 2009 |
Effect of Lianshu preparation on lipopolysaccharide-induced diarrhea in rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Berberine; Cholinesterase Inhibitors; Diarrhea; Drugs, C | 2009 |
Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea.
Topics: Acidosis; Animals; Animals, Newborn; Cattle; Cattle Diseases; Decision Trees; Diarrhea; Electrolytes | 2012 |
[Lactic acid in the feces of healthy infants and those with diarrhea].
Topics: Child; Diarrhea; Feces; Humans; Infant; Infant Welfare; Lactates; Lactic Acid | 1961 |
Investigations on the influence of serum D-lactate levels on clinical signs in calves with metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Suckling; Cattle; Cattle Diseases; Diarrh | 2004 |
Influence of D-lactate on metabolic acidosis and on prognosis in neonatal calves with diarrhoea.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Newborn; Blood Gas Analysis; Cattle; Catt | 2004 |
Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats.
Topics: Animals; Diarrhea; Garlic; Intestine, Small; Lactic Acid; Male; Malondialdehyde; Methotrexate; Plant | 2006 |
[Influence of selected Lactobacillus sp. on Clostridium difficile strains with different toxigenicity profile].
Topics: Antibiosis; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Diarrhea; Enterotoxins; | 2006 |
The effect of diet on fecal moisture, osmolarity of fecal extracts, products of bacterial fermentation and loss of minerals in feces of weaned pigs.
Topics: Acetates; Acetic Acid; Animal Feed; Animals; Bacteria; Diarrhea; Electrolytes; Fatty Acids, Volatile | 1984 |
Acid adaptation of Escherichia coli O157:H7 increases survival in acidic foods.
Topics: Acids; Adaptation, Physiological; Animals; Beverages; Diarrhea; Escherichia coli; Escherichia coli I | 1995 |
Can diarrhea induced by lactulose be reduced by prolonged ingestion of lactulose?
Topics: Adult; beta-Galactosidase; Defecation; Diarrhea; Feces; Female; Gastrointestinal Transit; Humans; Il | 1993 |
The ability of enteric diarrhoeal pathogens to ferment starch to short-chain fatty acids in vitro.
Topics: Butyrates; Butyric Acid; Diarrhea; Fatty Acids, Volatile; Fermentation; Humans; In Vitro Techniques; | 1998 |
Abdominal distension in collapsed diarrhoeic calves: biochemical findings and treatment.
Topics: Abomasum; Acidosis; Animals; Anions; Blood Glucose; Blood Urea Nitrogen; Carbon Dioxide; Cattle; Cat | 1999 |
Potentiation of the effectiveness of Lactobacillus casei in the prevention of E. coli induced diarrhea in conventional and gnotobiotic pigs.
Topics: Animals; Bacterial Adhesion; Colon; Diarrhea; Escherichia coli; Escherichia coli Infections; Germ-Fr | 1999 |
Blood oxygen binding in calves with naturally occurring diarrhea.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Animals, Newborn; Carbon Dioxide; Cattle; C | 2001 |
Both L- and D-lactate contribute to metabolic acidosis in diarrheic calves.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Suckling; Bacteria; Carbon Dioxide; Cattl | 2001 |
Organic acid profiles in feces of pigs with pathogenic or non-pathogenic diarrhea.
Topics: Animals; Anti-Infective Agents; Diarrhea; Dyspepsia; Enrofloxacin; Escherichia coli; Escherichia col | 2001 |
Colonic fermentation to short-chain fatty acids is decreased in antibiotic-associated diarrhea.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Colon; Diarrhea; Fatty | 1991 |
Gastrointestinal and metabolic effects of amylase inhibition in diabetics.
Topics: Aged; Amylases; Blood Glucose; Breath Tests; C-Peptide; Diabetes Mellitus, Type 2; Diarrhea; Dietary | 1988 |
Clinical evaluation of sodium bicarbonate, sodium L-lactate, and sodium acetate for the treatment of acidosis in diarrheic calves.
Topics: Acetates; Acetic Acid; Acidosis; Animals; Bicarbonates; Cattle; Cattle Diseases; Diarrhea; Double-Bl | 1985 |
Organic anions and the diarrhea of inflammatory bowel disease.
Topics: Anions; Citric Acid Cycle; Colitis, Ulcerative; Crohn Disease; Diarrhea; Fatty Acids, Volatile; Fece | 1988 |
Fecal organic anions in diarrhoeal diseases.
Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Colonic Neoplasms; Crohn Disease; Diarrhea; Fatty | 1987 |
Levels of beta-galactosidase and lactic acid, in the intestine, and blood glucose in pig scour.
Topics: Animals; Animals, Suckling; beta-Galactosidase; Blood Glucose; Diarrhea; Galactosidases; Intestinal | 1985 |