lactic acid has been researched along with Diabetic Neuropathies in 16 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have used diabetic autonomic neuropathy as a model of chronic pulmonary denervation to study the ventilatory response to incremental exercise in 20 diabetic subjects, 10 with (Dan+) and 10 without (Dan-) autonomic dysfunction, and in 10 normal control subjects." | 2.68 | Ventilatory response to exercise in diabetic subjects with autonomic neuropathy. ( Bottini, P; Casucci, G; Dottorini, ML; Puxeddu, E; Scionti, L; Sorbini, CA; Tantucci, C, 1996) |
| "We conclude that DAN, long IDDM duration per se, and antecedent recent hypoglycemia contribute to different extents to impaired adrenaline responses and hypoglycemia unawareness." | 1.30 | Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation. ( Bolli, GB; Bottini, P; Brunetti, P; Ciofetta, M; Del Sindaco, P; Di Vincenzo, A; Fanelli, C; Lalli, C; Lepore, M; Pampanelli, S; Porcellati, F, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, MK | 2 |
| Ament, XH | 1 |
| Yang, F | 1 |
| Liu, Y | 1 |
| Polydefkis, MJ | 1 |
| Pellerin, L | 1 |
| Morrison, BM | 1 |
| Bhusal, A | 1 |
| Rahman, MH | 2 |
| Lee, WH | 1 |
| Lee, IK | 2 |
| Suk, K | 2 |
| Kim, JH | 2 |
| Nam, Y | 1 |
| Lee, MG | 1 |
| Go, Y | 1 |
| Harris, RA | 1 |
| Park, DH | 1 |
| Kook, H | 1 |
| Hazekawa, M | 1 |
| Sakai, Y | 1 |
| Yoshida, M | 1 |
| Haraguchi, T | 1 |
| Morisaki, T | 1 |
| Uchida, T | 1 |
| Won, SJ | 1 |
| Jang, BG | 1 |
| Yoo, BH | 1 |
| Sohn, M | 1 |
| Lee, MW | 1 |
| Choi, BY | 1 |
| Song, HK | 1 |
| Suh, SW | 1 |
| Jensen, RV | 1 |
| Støttrup, NB | 1 |
| Kristiansen, SB | 1 |
| Bøtker, HE | 1 |
| Tilton, RG | 1 |
| Chang, K | 1 |
| Nyengaard, JR | 1 |
| Van den Enden, M | 1 |
| Ido, Y | 1 |
| Williamson, JR | 1 |
| McLellan, AC | 1 |
| Thornalley, PJ | 1 |
| Benn, J | 1 |
| Sonksen, PH | 1 |
| Tantucci, C | 1 |
| Bottini, P | 2 |
| Dottorini, ML | 1 |
| Puxeddu, E | 1 |
| Casucci, G | 1 |
| Scionti, L | 1 |
| Sorbini, CA | 1 |
| Fanelli, C | 1 |
| Pampanelli, S | 1 |
| Lalli, C | 1 |
| Del Sindaco, P | 1 |
| Ciofetta, M | 1 |
| Lepore, M | 1 |
| Porcellati, F | 1 |
| Di Vincenzo, A | 1 |
| Brunetti, P | 1 |
| Bolli, GB | 1 |
| Suzuki, S | 1 |
| Hinokio, Y | 1 |
| Ohtomo, M | 1 |
| Hirai, M | 1 |
| Hirai, A | 1 |
| Chiba, M | 1 |
| Kasuga, S | 1 |
| Satoh, Y | 1 |
| Akai, H | 1 |
| Toyota, T | 1 |
| Hilsted, J | 1 |
| Richter, EA | 1 |
| Madsbad, S | 1 |
| Tronier, B | 1 |
| Christensen, NJ | 1 |
| Hildebrandt, P | 1 |
| Galbo, H | 1 |
| Damkjaer, M | 1 |
| Yao, H | 1 |
| Sadoshima, S | 1 |
| Nishimura, Y | 1 |
| Fujii, K | 1 |
| Oshima, M | 1 |
| Ishitsuka, T | 1 |
| Fujishima, M | 1 |
| Low, PA | 3 |
| Schmelzer, JD | 3 |
| Ward, KK | 2 |
| Yao, JK | 1 |
| Curran, GL | 1 |
| Poduslo, JF | 1 |
| Ward, K | 1 |
| Brimijoin, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for lactic acid and Diabetic Neuropathies
| Article | Year |
|---|---|
Ventilatory response to exercise in diabetic subjects with autonomic neuropathy.
Topics: Adult; Anaerobic Threshold; Autonomic Nervous System Diseases; Blood Glucose; Carbon Dioxide; Diabet | 1996 |
The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation.
Topics: Adult; C-Peptide; Coenzymes; Deafness; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropat | 1998 |
14 other studies available for lactic acid and Diabetic Neuropathies
| Article | Year |
|---|---|
Reducing monocarboxylate transporter MCT1 worsens experimental diabetic peripheral neuropathy.
Topics: Animals; Axons; Behavior, Animal; Demyelinating Diseases; Diabetes Mellitus, Experimental; Diabetic | 2020 |
Satellite glia as a critical component of diabetic neuropathy: Role of lipocalin-2 and pyruvate dehydrogenase kinase-2 axis in the dorsal root ganglion.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Spinal; Inflammation; Lact | 2021 |
Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Ganglia, Spinal; G | 2016 |
Preparation of ONO-1301-loaded poly(lactide-co-glycolide) microspheres and their effect on nerve conduction velocity.
Topics: Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Neuropathie | 2011 |
Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Cell Death; Diabetic Neuropathies; Electrocardiograp | 2012 |
Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients.
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Hemodynamics; Humans; Ische | 2012 |
Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Eye; Fructos | 1995 |
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathi | 1994 |
Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 1; | 1997 |
Increased metabolic sensitivity towards adrenaline in diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Blood Glucose; Diabetic Neuropathies; Epinephrine; Fatty Acids, N | 1985 |
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo | 1989 |
Experimental chronic hypoxic neuropathy: relevance to diabetic neuropathy.
Topics: Animals; Diabetic Neuropathies; Disease Models, Animal; Electrophysiology; Glycated Hemoglobin; Hexo | 1986 |
Effect of hyperbaric oxygenation on normal and chronic streptozotocin diabetic peripheral nerves.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Biological Transport, Active; Diabetes Mellitus, | 1988 |
Ischemic conduction failure and energy metabolism in experimental diabetic neuropathy.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Neurop | 1985 |