Page last updated: 2024-10-17

lactic acid and Diabetic Ketoacidosis

lactic acid has been researched along with Diabetic Ketoacidosis in 47 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Diabetic Ketoacidosis: A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA.

Research Excerpts

ExcerptRelevanceReference
"Thiamine functions as an important cofactor in aerobic metabolism and thiamine deficiency can contribute to lactic acidosis."7.80The relationship between lactate and thiamine levels in patients with diabetic ketoacidosis. ( Berg, K; Donnino, MW; Gautam, S; Giberson, T; Graver, A; Liu, X; Moskowitz, A; Uber, A, 2014)
"The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes."7.79Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013)
"Bumetanide treatment increased ATP/Pi and PCr/Pi and ameliorated the declines in these values with insulin/saline treatment."5.36Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. ( Anderson, SE; Glaser, N; O'Donnell, ME; Tancredi, DJ; Yuen, N, 2010)
"Thiamine functions as an important cofactor in aerobic metabolism and thiamine deficiency can contribute to lactic acidosis."3.80The relationship between lactate and thiamine levels in patients with diabetic ketoacidosis. ( Berg, K; Donnino, MW; Gautam, S; Giberson, T; Graver, A; Liu, X; Moskowitz, A; Uber, A, 2014)
"The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes."3.79Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013)
" We assessed the effect of a novel oral antilipolytic agent, N-[(1S, trans)-2-hydroxycyclopentyl]adenosine (GR 79236), in experimental diabetic ketoacidosis."3.69Improvement of ketoacidosis in the diabetic rat after the administration of the oral antilipolytic agent GR 79236. ( Mikhailidis, DP; Strong, P; Thompson, CS, 1994)
"Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity."3.68[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus]. ( Baturin, AA; Marchenko, LF; Terent'eva, EA, 1991)
"Hyperlactatemia was not associated with length of time to DKA resolution and length of hospital stay."3.01Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit. ( Li, Y; Liu, J; Yan, H, 2021)
"Post mortem diagnosis of glucose metabolism disorders can be difficult and vague because of the lack of characteristic morphological findings."2.47Disorders of glucose metabolism-post mortem analyses in forensic cases: part I. ( Hess, C; Madea, B; Musshoff, F, 2011)
"Hyperlactatemia was associated with in-hospital mortality (Odds Ratio [OR] 1."1.91Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis. ( Doola, R; Kumar, A; Laupland, KB; Ramanan, M; Shaikh, A; Tabah, A; Zahumensky, A, 2023)
"We reviewed episodes of diabetic ketoacidosis from 79 diabetes patients (one episode per patient)."1.72Hyperlactatemia in diabetic ketoacidosis. ( Brooks, GA; Lazar, AA; Masharani, U; Strycker, LA; Wu, K, 2022)
"Sixteen children and adolescents with type 1 diabetes (T1D) had blood samples obtained, 6-12 hours into treatment, at three weeks and three months post start of treatment."1.56Soluble Receptor for Glycation End-products Concentration Increases Following the Treatment of Severe Diabetic Ketoacidosis ( Artlett, CM; Blum, J; Hoffman, WH; Ikeda, T; Ishikawa, T; Tani, N, 2020)
"Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus with potentially fatal consequences, is characterized by hyperglycemia and metabolic acidosis due to the accumulation of ketone bodies, which requires people with diabetes to monitor both glucose and ketone bodies."1.56Microneedle-Based Detection of Ketone Bodies along with Glucose and Lactate: Toward Real-Time Continuous Interstitial Fluid Monitoring of Diabetic Ketosis and Ketoacidosis. ( Aghavali, R; Barfidokht, A; Dassau, E; Mercier, PP; Moonla, C; Tangkuaram, T; Tehrani, F; Teymourian, H; Vargas, E; Wang, J, 2020)
"Acute kidney injury was categorized into three stages using the Kidney Disease Improving Global Outcomes scale."1.51Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study. ( Gendler, Y; Kadmon, G; Kaplan, E; Nahum, E; Weissbach, A; Zur, N, 2019)
"sixty patients with diabetic ketoacidosis were enrolled in the study; in which 24 (40%) patients were died within 5 days after admission."1.40Predictors of five days mortality in diabetic ketoacidosis patients: a prospective cohort study. ( Pohan, HT; Sutrisna, B; Suwarto, S; Waspadji, S, 2014)
"Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal."1.39Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013)
"A high anion gap in diabetic ketoacidosis (DKA) suggests that some unmeasured anions must contribute to the generation of the anion gap."1.37Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. ( Adeli, K; Krahn, J; Lu, J; Meng, QH; Randell, E; Zello, GA, 2011)
"Bumetanide treatment increased ATP/Pi and PCr/Pi and ameliorated the declines in these values with insulin/saline treatment."1.36Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. ( Anderson, SE; Glaser, N; O'Donnell, ME; Tancredi, DJ; Yuen, N, 2010)
"Death was, therefore, due to diabetic ketoacidosis complicated by hypothermia."1.36Erosive gastritis, Armanni-Ebstein phenomenon and diabetic ketoacidosis. ( Byard, RW; Zhou, C, 2010)
"During diabetic ketoacidosis (DKA), serum ketone concentrations markedly increase; however, little is known about whether ketone bodies accumulate in cerebral tissues during DKA."1.33Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosis. ( Barnes, PD; Buonocore, MH; Dicarlo, J; Glaser, N; Kuppermann, N; Marcin, J; Neely, EK; Wootton-Gorges, SL, 2005)
"Diabetic ketoacidosis (DKA) and alcoholic ketoacidosis (AKA) are two medical emergencies characterized by elevated total ketone body concentration."1.31Differences in metabolic and hormonal milieu in diabetic- and alcohol-induced ketoacidosis. ( Bhoola, SM; DiGirolamo, M; Isaacs, SD; Kokko, JP; Tuvlin, JA; Umpierrez, GE, 2000)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.02)18.7374
1990's6 (12.77)18.2507
2000's7 (14.89)29.6817
2010's20 (42.55)24.3611
2020's6 (12.77)2.80

Authors

AuthorsStudies
Masharani, U1
Strycker, LA1
Lazar, AA1
Wu, K1
Brooks, GA1
Kumar, A1
Doola, R1
Zahumensky, A1
Shaikh, A1
Tabah, A1
Laupland, KB1
Ramanan, M1
Hoffman, WH1
Ishikawa, T1
Blum, J1
Tani, N1
Ikeda, T1
Artlett, CM1
Jenei, K1
Szatmári, I1
Szabó, E1
Mariam, A1
Luczay, A1
Zsidegh, P1
Tóth-Heyn, P1
Teymourian, H1
Moonla, C1
Tehrani, F1
Vargas, E1
Aghavali, R1
Barfidokht, A1
Tangkuaram, T1
Mercier, PP1
Dassau, E1
Wang, J1
Ibrahim, A1
Bayramoglu, B1
Hokenek, NM1
Tekyol, D1
Liu, J1
Yan, H1
Li, Y1
Claus, P1
Gimenes, AM1
Castro, JR1
Mantovani, MM1
Kanayama, KK1
Simões, DMN1
Schwartz, DS1
Heimer, J1
Gascho, D1
Chatzaraki, V1
Knaute, DF1
Sterzik, V1
Martinez, RM1
Thali, MJ1
Zoelch, N1
Weissbach, A1
Zur, N1
Kaplan, E1
Kadmon, G1
Gendler, Y1
Nahum, E1
Bo, J1
Li, W1
Chen, Z1
Wadden, DG1
Randell, E2
Zhou, H1
Lu, J2
Meng, QH2
Moskowitz, A1
Graver, A1
Giberson, T1
Berg, K1
Liu, X1
Uber, A1
Gautam, S1
Donnino, MW1
Keltanen, T1
Sajantila, A1
Palo, JU1
Partanen, T1
Valonen, T1
Lindroos, K1
Ciechanowska, A1
Ladyzynski, P1
Wojcicki, JM1
Sabalinska, S1
Krzymien, J1
Pulawska, E1
Karnafel, W1
Foltynski, P1
Kawiak, J1
Suwarto, S1
Sutrisna, B1
Waspadji, S1
Pohan, HT1
Hess, C2
Stockhausen, S1
Kernbach-Wighton, G1
Madea, B2
Love, IY1
Perl, S1
Rapoport, MJ1
Glaser, N3
Yuen, N2
Anderson, SE1
Tancredi, DJ1
O'Donnell, ME1
Byard, RW1
Zhou, C1
Titov, VN1
Dmitriev, LF1
Krylin, VA1
Dmitriev, VA1
Musshoff, F1
Zello, GA1
Adeli, K1
Krahn, J1
Wetter, J1
Gohlke, BC1
Woelfle, JF1
Palmiere, C1
Sporkert, F1
Vaucher, P1
Werner, D1
Bardy, D1
Rey, F1
Lardi, C1
Brunel, C1
Augsburger, M1
Mangin, P1
Ngo, C1
Anderson, S1
Trifu, A1
O'Donnell, M1
Shimizu, I1
Ishikawa, E1
Fukuda, T1
Okazaki, S1
Jager, AV1
Tavares, MF1
Shahi, SK1
Ranga, S1
Arulselvi, S1
EWY, GA1
PABICO, RC1
MAHER, JF1
MINTZ, DH1
MENGIS, CL1
Wootton-Gorges, SL1
Buonocore, MH1
Kuppermann, N1
Marcin, J1
Dicarlo, J1
Neely, EK1
Barnes, PD1
Osuna, E1
Vivero, G1
Conejero, J1
Abenza, JM1
Martínez, P1
Luna, A1
Pérez-Cárceles, MD1
Ogihara, T1
Tanaka, Y1
Funk, GC1
Jiang, GY1
Geng, DZ1
Tripathy, BB1
Garabadu, NK1
Samal, KC1
Christopher, MM1
Broussard, JD1
Fallin, CW1
Drost, NJ1
Peterson, ME1
Thompson, CS1
Strong, P1
Mikhailidis, DP1
Pepper, GM1
Schwartz, M1
Umpierrez, GE1
DiGirolamo, M1
Tuvlin, JA1
Isaacs, SD1
Bhoola, SM1
Kokko, JP1
Kawanishi, K1
Ishida, T1
Marchenko, LF1
Baturin, AA1
Terent'eva, EA1
Ritz, S1
Kaatsch, HJ1
Fulop, M1
Bock, J1
Ben-Ezra, J1
Antony, M1
Danzig, J1
Gage, JS1
Kosugi, K1
Scofield, RF1
Chandramouli, V1
Kumaran, K1
Schumann, WC1
Landau, BR1
Yang, DP1
Liang, JZ1
Luo, ZT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults[NCT03520569]Early Phase 115 participants (Actual)Interventional2019-02-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Augmentation Index Between Baseline and After 2 Hour Insulin Clamp

The augmentation index (AIx) measured at the radial artery is a measure of systemic arterial stiffness, and is defined as the ratio of augmentation (Δ P) to central pulse pressure and expressed as percent. AIx = (ΔP/PP) x 100, where P = pressure and PP = Pulse Pressure. Higher percentages indicate increased arterial stiffness. (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp

Interventionpercentage (Mean)
Octreotide- Euglycemia-4.15
Octreotide - Euglycemia- Insulin Clamp-2.23
Octreotide- Hyperglycemia-4.80
Octreotide- Hyperglycemia - Insulin Clamp-8.45

Change in Flow Mediated Dilation (FMD) Between Baseline and After 2 Hour Insulin Clamp

Flow mediated dilation measures the change in brachial diameter in response to 5 minutes of ischemia using B-mode ultrasound. It provides an index of nitric oxide generation by the endothelium . (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp

Intervention% change (Mean)
Octreotide- Euglycemia11.8
Octreotide - Euglycemia- Insulin Clamp11.8
Octreotide- Hyperglycemia8.9
Octreotide- Hyperglycemia - Insulin Clamp8.95

Change in Pulse Wave Velocity (PWV) Between Baseline and After 2 Hour Insulin Clamp

The time required for a blood pressure wave to travel from the carotid to the femoral artery was measured in meter/sec. This is a measurement of central artery stiffness. Higher numbers indicate stiffer vessels (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp

Interventionm/sec (Mean)
Octreotide- Euglycemia5.21
Octreotide - Euglycemia- Insulin Clamp5.06
Octreotide- Hyperglycemia4.79
Octreotide- Hyperglycemia - Insulin Clamp5.07

Reviews

3 reviews available for lactic acid and Diabetic Ketoacidosis

ArticleYear
Disorders of glucose metabolism-post mortem analyses in forensic cases: part I.
    International journal of legal medicine, 2011, Volume: 125, Issue:2

    Topics: Blood Proteins; Diabetes Mellitus; Diabetic Ketoacidosis; Forensic Pathology; Fructosamine; Glucose;

2011
[Diabetic lactic acidosis].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Sep-28, Volume: Suppl 3

    Topics: Acidosis, Lactic; Contraindications; Diabetic Ketoacidosis; Humans; Hypoglycemic Agents; Insulin; La

2006
[Stewart's acid-base approach].
    Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:13-14

    Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Anions; Bicarbonates; Cations; Diabetic Ketoacidosis; El

2007

Trials

1 trial available for lactic acid and Diabetic Ketoacidosis

ArticleYear
Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit.
    BMC endocrine disorders, 2021, May-27, Volume: 21, Issue:1

    Topics: Biomarkers; Child; Diabetic Ketoacidosis; Female; Follow-Up Studies; Humans; Hyperlactatemia; Intens

2021

Other Studies

43 other studies available for lactic acid and Diabetic Ketoacidosis

ArticleYear
Hyperlactatemia in diabetic ketoacidosis.
    Diabetic medicine : a journal of the British Diabetic Association, 2022, Volume: 39, Issue:4

    Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hyperglycemi

2022
Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis.
    Journal of critical care, 2023, Volume: 78

    Topics: Adult; Cohort Studies; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hyperlactatemia; Intensive

2023
Soluble Receptor for Glycation End-products Concentration Increases Following the Treatment of Severe Diabetic Ketoacidosis
    Journal of clinical research in pediatric endocrinology, 2020, 06-03, Volume: 12, Issue:2

    Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glycation End Products,

2020
[Changes of lactate levels in diabetic ketoacidosis and in newly diagnosed type 1 diabetes mellitus].
    Orvosi hetilap, 2019, Volume: 160, Issue:45

    Topics: Blood Gas Analysis; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Femal

2019
Microneedle-Based Detection of Ketone Bodies along with Glucose and Lactate: Toward Real-Time Continuous Interstitial Fluid Monitoring of Diabetic Ketosis and Ketoacidosis.
    Analytical chemistry, 2020, 01-21, Volume: 92, Issue:2

    Topics: Biosensing Techniques; Blood Glucose Self-Monitoring; Diabetic Ketoacidosis; Electrochemical Techniq

2020
Lactate clearance during the first 2 hours after hospital admission: A useful biomarker for predicting 30-day mortality in patients with diabetic ketoacidosis.
    International journal of clinical practice, 2021, Volume: 75, Issue:7

    Topics: Biomarkers; Cohort Studies; Diabetic Ketoacidosis; Hospitals; Humans; Lactic Acid; Retrospective Stu

2021
Blood lactate concentration in diabetic dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2017, Volume: 58, Issue:8

    Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Dog Diseases; Do

2017
Postmortem
    International journal of legal medicine, 2018, Volume: 132, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Diabetic Ketoacidosis; Glucose; Humans; Ketone

2018
Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2019, Volume: 20, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Blood Glucose; Child; Child, Preschool; Critical Illness; Diabetic

2019
D-lactate: a novel contributor to metabolic acidosis and high anion gap in diabetic ketoacidosis.
    Clinical chemistry, 2013, Volume: 59, Issue:9

    Topics: Acid-Base Equilibrium; Diabetic Ketoacidosis; Humans; Lactic Acid; Prognosis

2013
The relationship between lactate and thiamine levels in patients with diabetic ketoacidosis.
    Journal of critical care, 2014, Volume: 29, Issue:1

    Topics: Acidosis, Lactic; Adult; Comorbidity; Diabetic Ketoacidosis; Female; Humans; Lactic Acid; Male; Midd

2014
Assessment of Traub formula and ketone bodies in cause of death investigations.
    International journal of legal medicine, 2013, Volume: 127, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl

2013
Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis.
    The International journal of artificial organs, 2013, Volume: 36, Issue:12

    Topics: Adipose Tissue; Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus

2013
Predictors of five days mortality in diabetic ketoacidosis patients: a prospective cohort study.
    Acta medica Indonesiana, 2014, Volume: 46, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Aged; Bicarbonates; Blood Glucose; Coma; Diabetic Ketoacidosis; Female

2014
Death due to diabetic ketoacidosis: Induction by the consumption of synthetic cannabinoids?
    Forensic science international, 2015, Volume: 257

    Topics: Acetone; Adult; Cannabinoids; Designer Drugs; Diabetic Ketoacidosis; Fatal Outcome; Forensic Toxicol

2015
A Rare Case of Caffeine Storm due to Excessive Coca-Cola Consumption.
    The Israel Medical Association journal : IMAJ, 2016, Volume: 18, Issue:6

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Diabetic Ketoacidosis; Diagnosis, Differential;

2016
Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide.
    Diabetes, 2010, Volume: 59, Issue:3

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Bumetanide; Cerebrovascular Circulation; Creatinine; Dia

2010
Erosive gastritis, Armanni-Ebstein phenomenon and diabetic ketoacidosis.
    Forensic science, medicine, and pathology, 2010, Volume: 6, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adult; Autopsy; Diabetic Ketoacidosis; Fatal Outcome; Gastritis; Glucose; Hum

2010
[Methylglyoxal--a test for impaired biological functions of exotrophy and endoecology, low glucose level in the cytosol and gluconeogenesis from fatty acids (a lecture)].
    Klinicheskaia laboratornaia diagnostika, 2010, Issue:3

    Topics: Animals; Cytosol; Diabetes Mellitus; Diabetic Ketoacidosis; Energy Metabolism; Fatty Acids; Gluconeo

2010
Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis.
    Clinica chimica acta; international journal of clinical chemistry, 2011, Jan-30, Volume: 412, Issue:3-4

    Topics: 3-Hydroxybutyric Acid; Bicarbonates; Blood Glucose; Diabetic Ketoacidosis; Female; Humans; Lactic Ac

2011
Hyperglycemic hyperosmolar state as initial manifestation of pediatric insulin-dependent diabetes.
    Klinische Padiatrie, 2012, Volume: 224, Issue:1

    Topics: Autoantibodies; Blood Glucose; Child, Preschool; Combined Modality Therapy; Creatine; Diabetes Melli

2012
Is the formula of Traub still up to date in antemortem blood glucose level estimation?
    International journal of legal medicine, 2012, Volume: 126, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Blood Glucose; Diabetic Ketoacidosis; Female; Forensi

2012
Effects of hyperglycemia and effects of ketosis on cerebral perfusion, cerebral water distribution, and cerebral metabolism.
    Diabetes, 2012, Volume: 61, Issue:7

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Edema; Cerebrum; Diabetes Mellitus, Experiment

2012
[Blood glucose, urinary glucose, blood ketone bodies, urine ketone bodies, blood lactic acid, and blood pyruvic acid].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 3

    Topics: Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glycosuria; Humans; Ketone Bodies;

2012
Evaluation of diabetic ketoacidosis-related ionic metabolites in human blood serum by capillary electrophoresis.
    Electrophoresis, 2003, Volume: 24, Issue:7-8

    Topics: Diabetic Ketoacidosis; Electrolytes; Electrophoresis, Capillary; Humans; Ions; Keto Acids; Lactic Ac

2003
Lactate--a diagnostic indicator.
    Indian journal of pathology & microbiology, 2002, Volume: 45, Issue:3

    Topics: Acidosis; Diabetic Ketoacidosis; Energy Metabolism; Humans; Lactic Acid

2002
LACTATE ACIDOSIS ASSOCIATED WITH PHENFORMIN THERAPY AND LOCALIZED TISSUE HYPOXIA. REPORT OF A CASE TREATED BY HEMODIALYSIS.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Acidosis; Black People; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Ischemia; Kidney; Kidneys,

1963
LACTIC ACID ACIDEMIA AND PHENFORMIN.
    Rocky Mountain medical journal, 1964, Volume: 61

    Topics: Acidosis; Acidosis, Lactic; Blood; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Lactates; Lacti

1964
Detection of cerebral {beta}-hydroxy butyrate, acetoacetate, and lactate on proton MR spectroscopy in children with diabetic ketoacidosis.
    AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Child; Diabetic Ketoacidosis; Female; Humans; Lactic Acid; Mag

2005
Postmortem vitreous humor beta-hydroxybutyrate: its utility for the postmortem interpretation of diabetes mellitus.
    Forensic science international, 2005, Oct-29, Volume: 153, Issue:2-3

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cadaver; Diabetic Ket

2005
[Treatment of diabetic lactic acidosis].
    Zhonghua yi xue za zhi, 1984, Volume: 64, Issue:3

    Topics: Diabetic Ketoacidosis; Humans; Lactates; Lactic Acid

1984
[Report of 3 cases of diabetes complicated by lactic acidosis].
    Zhonghua yi xue za zhi, 1984, Volume: 64, Issue:3

    Topics: Aged; Diabetic Ketoacidosis; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged

1984
Phenformin and other antidiabetic drugs on blood lactic acid.
    The Journal of the Association of Physicians of India, 1984, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Child; Diabetic Ketoacidosis; Female; Humans; Hypoglycemic Agents; India; L

1984
Increased serum D-lactate associated with diabetic ketoacidosis.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cats; Diabetic Ketoacidosis; Hydroxybutyrates; Lactat

1995
Improvement of ketoacidosis in the diabetic rat after the administration of the oral antilipolytic agent GR 79236.
    Clinical science (London, England : 1979), 1994, Volume: 86, Issue:5

    Topics: Adenosine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Fatty Aci

1994
Lactic acidosis associated with Glucophage use in a man with normal renal and hepatic function.
    Diabetes care, 1997, Volume: 20, Issue:2

    Topics: Acidosis, Lactic; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Drug Therapy, Combination; Human

1997
Differences in metabolic and hormonal milieu in diabetic- and alcohol-induced ketoacidosis.
    Journal of critical care, 2000, Volume: 15, Issue:2

    Topics: Adult; Alcoholism; Blood Glucose; Diabetic Ketoacidosis; Diagnosis, Differential; Epinephrine; Femal

2000
[Lactic acidosis inpatients with diabetes mellitus].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Bicarbonates; Blood Glucose; Diabetic Ketoacidosis; Dichl

1991
[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
    Pediatriia, 1991, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Com

1991
[Postmortem diagnosis of fatal diabetic metabolic dyscontrol: what is the significance of cerebrospinal fluid and vitreous body total values and HbA1?].
    Der Pathologe, 1990, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood-Brain Barrier; Blood-Retinal Barrie

1990
Plasma lactate and 3-hydroxybutyrate levels in patients with acute ethanol intoxication.
    The American journal of medicine, 1986, Volume: 80, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Alcoholic Intoxication; Blood Glucose; Diabetic K

1986
Pathways of acetone's metabolism in the rat.
    The Journal of biological chemistry, 1986, Mar-25, Volume: 261, Issue:9

    Topics: Acetone; Acetyl Coenzyme A; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Female;

1986
[Alteration of blood lactic acid levels in biguanide therapy in diabetics].
    Sichuan yi xue yuan xue bao = Acta Academiae Medicinae Sichuan, 1985, Volume: 16, Issue:2

    Topics: Biguanides; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Humans; Lactates; Lacti

1985