Page last updated: 2024-10-17

lactic acid and Depressive Disorder

lactic acid has been researched along with Depressive Disorder in 20 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
" Many double-blind controlled studies have shown that imipramine effectively ameliorates panic attacks and agoraphobia."4.77Panic disorder: response to sodium lactate and treatment with antidepressants. ( Rifkin, A; Siris, SG, 1985)
"Anxiogenic challenge studies (intravenous lactate infusion and oral fenfluramine challenge) were conducted in 17 patients with panic disorder (PD), 12 patients with major depressive disorder and a history of panic attacks (MDD-PD), 27 patients with major depression and no history of panic (MDD), and 12 normal controls."3.68Differential responses to anxiogenic challenge studies in patients with major depressive disorder and panic disorder. ( Targum, SD, 1990)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's3 (15.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LOWENBACH, H1
GREENHILL, MH1
Voderholzer, U1
Dersch, R1
Dickhut, HH1
Herter, A1
Freyer, T1
Berger, M1
Pohl, R2
Rainey, JM1
Gershon, S2
McArthur, P1
Kellner, CH1
Pritchett, JT1
Beale, MD1
Burns, CM1
Bernstein, HJ1
Ruby, RN1
Lambiotte, C1
Levine, J1
Panchalingam, K1
Pettegrew, JW1
Cowley, DS5
Dager, SR5
Roy-Byrne, PP2
Avery, DH1
Dunner, DL5
Targum, SD1
Dorsa, DM1
Schmidt, P1
Cannon, RO1
Diem, H1
Rubinow, DR1
Martinsen, EW1
Strand, J1
Paulsson, G1
Kaggestad, J1
Balon, R1
Jordan, M1
Yeragani, VK1
Gorman, JM2
McGrath, PJ3
Stewart, JW3
Liebowitz, MR1
Markowitz, JM1
Quitkin, FM2
Klein, DF1
Murray, JB1
Rifkin, A1
Siris, SG1
Harrison, W1
Rabkin, J1
Robinson, D1

Reviews

2 reviews available for lactic acid and Depressive Disorder

ArticleYear
Changes in the drug treatment of anxiety disorders.
    Psychopathology, 1984, Volume: 17 Suppl 1

    Topics: Agoraphobia; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder

1984
Panic disorder: response to sodium lactate and treatment with antidepressants.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1

    Topics: Agoraphobia; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Fear; Humans; Imipramine;

1985

Trials

3 trials available for lactic acid and Depressive Disorder

ArticleYear
Changes in the drug treatment of anxiety disorders.
    Psychopathology, 1984, Volume: 17 Suppl 1

    Topics: Agoraphobia; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder

1984
Lactate vulnerability after alprazolam versus placebo treatment of panic disorder.
    Biological psychiatry, 1991, Jul-01, Volume: 30, Issue:1

    Topics: Adult; Alprazolam; Anxiety Disorders; Arousal; Depressive Disorder; Dose-Response Relationship, Drug

1991
Microvascular angina and panic disorder.
    International journal of psychiatry in medicine, 1989, Volume: 19, Issue:4

    Topics: Agoraphobia; Angina Pectoris, Variant; Anxiety Disorders; Arousal; Coronary Angiography; Coronary Va

1989

Other Studies

16 other studies available for lactic acid and Depressive Disorder

ArticleYear
The effect of oral administration of lactic acid upon the clinical course of depressive states.
    The Journal of nervous and mental disease, 1947, Volume: 105, Issue:4

    Topics: Administration, Oral; Bipolar Disorder; Depression; Depressive Disorder; Humans; Lactic Acid; Mental

1947
Physical fitness in depressive patients and impact of illness course and disability.
    Journal of affective disorders, 2011, Volume: 128, Issue:1-2

    Topics: Adult; Anaerobic Threshold; Body Mass Index; Case-Control Studies; Depressive Disorder; Disability E

2011
Panic induced by lactate infusion during electroconvulsive therapy?
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:1

    Topics: Depressive Disorder; Electroconvulsive Therapy; Humans; Infusions, Intravenous; Isotonic Solutions;

1994
Stability of CSF metabolites measured by proton NMR.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:7

    Topics: Amino Acids; Depressive Disorder; Glucose; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectro

2000
Differential responses to anxiogenic challenge studies in patients with major depressive disorder and panic disorder.
    Biological psychiatry, 1990, Jul-01, Volume: 28, Issue:1

    Topics: Administration, Oral; Adult; Anxiety Disorders; Arousal; Depressive Disorder; Diagnosis, Differentia

1990
Plasma beta-endorphin response to lactate infusion.
    Biological psychiatry, 1989, Jan-15, Volume: 25, Issue:2

    Topics: Adult; Agoraphobia; beta-Endorphin; Depressive Disorder; Fear; Female; Humans; Infusions, Intravenou

1989
Physical fitness level in patients with anxiety and depressive disorders.
    International journal of sports medicine, 1989, Volume: 10, Issue:1

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Female; Heart Rate; Humans; Institutionalization; Lac

1989
Lactate response in patients with primary major depression.
    Psychiatry research, 1989, Volume: 27, Issue:3

    Topics: Depressive Disorder; Fear; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Panic

1989
Family history of anxiety disorders in control subjects with lactate-induced panic attacks.
    The American journal of psychiatry, 1989, Volume: 146, Issue:10

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Family; Fear; Female; Humans; Lactates; Lactic Acid;

1989
Panic disorders.
    Modern problems of pharmacopsychiatry, 1987, Volume: 22

    Topics: Antidepressive Agents; Anxiety Disorders; Carbon Dioxide; Depressive Disorder; Diagnosis, Differenti

1987
Lactate provocation of panic attacks in depressed outpatients.
    Psychiatry research, 1988, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Depressive Disorder; Fear; Humans; Infusions, Intravenous; Lac

1988
Psychopharmacological investigation of panic disorder by means of lactate infusion.
    The Journal of general psychology, 1987, Volume: 114, Issue:3

    Topics: Anxiety Disorders; Depressive Disorder; Diagnosis, Differential; Fear; Humans; Infusions, Intravenou

1987
Lactate infusions in major depression without panic attacks.
    Journal of psychiatric research, 1987, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Diagnosis, Differential; Fear; Fema

1987
Lactate-induced panic in primary affective disorder.
    The American journal of psychiatry, 1986, Volume: 143, Issue:5

    Topics: Adult; Agoraphobia; Anxiety Disorders; Depressive Disorder; Diagnosis, Differential; Fear; Female; H

1986
Lactate infusion in patients with depression and anxiety.
    Psychopharmacology bulletin, 1985, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Anxiety; Depressive Disorder; Fear; Humans; Lactates; Lactic Acid; Middle A

1985
Atypical panic attacks in major depression.
    The American journal of psychiatry, 1985, Volume: 142, Issue:10

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Fear; Humans; Lactates; Lactic Acid; Male; Panic

1985