Page last updated: 2024-10-18

lactic acid and Demineralization, Tooth

lactic acid has been researched along with Demineralization, Tooth in 90 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The increase in root caries is a serious problem as society ages."1.72Demonstration of an optical dentin hardness measuring device using bovine dentin with different demineralization times. ( Awazu, K; Hazama, H; Kondo, S; Mine, A; Okumura, S; Tanimoto, H; Tomioka, Y; Yamaguchi, S; Yamamoto, K; Yasuo, K; Yoshikawa, K, 2022)
"All treatments (fluorides and CHX) significantly reduced the biofilm viability compared to placebo varnish and negative control."1.51Protective Effect of 4% Titanium Tetrafluoride Varnish on Dentin Demineralization Using a Microcosm Biofilm Model. ( Buzalaf, MAR; Dos Santos, DMS; Magalhães, AC; Pires, JG; Salomão, PMA; Silva, AB, 2019)
"The aim of this study was to compare the effects of acidulated phosphate fluoride (APF) gel, calcium phosphopeptide-amorphous calcium phosphate (CPP/ACP) paste alone and in combination with CO2 laser on the resistance of enamel to acid solubility."1.48A comparative evaluation of APF gel, CPP/ACP paste alone and in combination with carbon dioxide laser on human enamel resistance to acid solubility using atomic absorption spectrometry: an in-vitro study. ( Dehghan Khalili, S; Fekrazad, R; Nozari, A; Rafiee, A, 2018)
"In vitro root caries were created using an acidified gel (pH 4."1.39Fluoride dentifrice containing xylitol: in vitro root caries formation. ( Flaitz, CM; García-Godoy, F; Hicks, J; Kao, LM, 2013)
"Early detection of dental caries is vital if improved patient outcomes are to be achieved by reversal of the demineralization process."1.39Characterizing and identifying incipient carious lesions in dental enamel using micro-Raman spectroscopy. ( Dadlani, D; Mahoney, D; Mann, AB; Mohanty, B, 2013)
" Changes in mineral distribution effected by F were most pronounced in MeC lesions, with remineralization/mineral redeposition in the original lesion body at the expense of sound enamel beyond the original lesion in a dose-response manner."1.38Effect of fluoride, lesion baseline severity and mineral distribution on lesion progression. ( Butler, A; Hara, AT; Lippert, F; Lynch, RJ, 2012)
"Three measurements of carious dentin depth were made in each specimen by CLSM."1.35Confocal laser scanning microscopic analysis of the depth of dentin caries-like lesions in primary and permanent teeth. ( Correr-Sobrinho, L; de Carvalho, FG; de Fucio, SB; Puppin-Rontani, RM; Sinhoreti, MA, 2008)
"Lactic acid (pH = 4."1.32Morphological evaluation of enamel surface after application of two 'home' whitening products. ( Marchionni, S; Mazzoni, A; Nucci, C; Piana, G; Prati, C, 2004)

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.11)18.7374
1990's18 (20.00)18.2507
2000's28 (31.11)29.6817
2010's38 (42.22)24.3611
2020's5 (5.56)2.80

Authors

AuthorsStudies
Guntermann, L1
Rohrbach, A1
Schäfer, E1
Dammaschke, T1
Kondo, S1
Hazama, H1
Tomioka, Y1
Mine, A1
Yamaguchi, S1
Okumura, S1
Tanimoto, H1
Yasuo, K1
Yoshikawa, K1
Yamamoto, K1
Awazu, K1
Wong, PYW3
Lim, SL3
Loi, STY3
Mei, ML3
Li, KC3
Aziz, S3
Ekambaram, M3
Saha, S1
Chopra, A1
Kamath, SU1
Kashyap, NN1
Zhang, A1
Chen, R1
Aregawi, W1
He, Y1
Wang, S1
Aparicio, C1
Rudney, J1
Chew, HP1
Fok, AS1
Saeki, K2
Chien, YC2
Nonomura, G2
Chin, AF1
Habelitz, S2
Gower, LB1
Marshall, SJ3
Marshall, GW3
Piemjai, M1
Chantarawej, P1
Nakabayashi, N1
Garcia-Godoy, F3
Nozari, A1
Rafiee, A1
Dehghan Khalili, S1
Fekrazad, R1
Wiewiora, C1
Armbruster, P1
Lallier, T1
Ballard, R1
Dos Santos, DMS1
Pires, JG2
Silva, AB1
Salomão, PMA1
Buzalaf, MAR1
Magalhães, AC4
Braga, AS1
Andrade, FB1
Saldanha, LL1
Dokkedal, AL1
Oliveira, RC1
Endo, H1
Kawamoto, R2
Takahashi, F2
Takenaka, H1
Yoshida, F1
Nojiri, K1
Takamizawa, T1
Miyazaki, M3
Kao, LM1
Flaitz, CM1
Hicks, J1
Do, D1
Orrego, S1
Majd, H1
Ryou, H1
Mutluay, MM1
Xu, HHK1
Arola, D1
Cantore, R1
Petrou, I1
Lavender, S2
Santarpia, P2
Liu, Z2
Gittins, E2
Vandeven, M1
Cummins, D1
Sullivan, R3
Utgikar, N1
Ilie, O1
van Turnhout, AG1
van Loosdrecht, MC1
Picioreanu, C1
Newby, EE1
Martinez-Mier, EA1
Hara, A1
Lippert, F4
Kelly, SA1
Fleming, N1
Butler, A3
Bosma, ML1
Zero, DT1
Kaga, M1
Kakuda, S1
Ida, Y1
Toshima, H2
Hashimoto, M1
Endo, K2
Sano, H1
Iino, M1
Murayama, R2
Shimamura, Y1
Kurokawa, H2
Furuichi, T1
Suzuki, T1
Scholtanus, JD1
van der Hoorn, W1
Ozcan, M1
Huysmans, MC1
Roeters, JF1
Kleverlaan, CJ1
Feilzer, AJ1
Al-Khateeb, SN1
Tarazi, SJ1
Al Maaitah, EF1
Al-Batayneh, OB1
Abu Alhaija, ES1
Hornby, K1
Ricketts, SR1
Philpotts, CJ1
Joiner, A1
Schemehorn, B1
Willson, R1
Zhang, M1
He, LB1
Exterkate, RA1
Cheng, L1
Li, JY1
Ten Cate, JM8
Crielaard, W1
Deng, DM1
Vyavhare, S1
Sharma, DS1
Kulkarni, VK1
Schwendicke, F1
Eggers, K1
Meyer-Lueckel, H1
Dörfer, C1
Kovalev, A1
Gorb, S1
Paris, S1
Kohda, N1
Iijima, M1
Kawaguchi, K1
Muguruma, T1
Mizoguchi, I1
Shibasaki, S1
Delecrode, TR1
Siqueira, WL1
Zaidan, FC1
Bellini, MR1
Moffa, EB1
Mussi, MC1
Xiao, Y1
Buzalaf, MA3
Burwell, AK1
Fernandez-Martinez, A1
Pugach, MK1
Ho, SP1
Rapozo-Hilo, M1
Featherstone, JD2
Yang, SY1
Kwon, JS1
Kim, KN1
Kim, KM1
Fawzy, AS1
Priyadarshini, BM1
Selvan, ST1
Lu, TB1
Neo, J1
de Carvalho, FG1
de Fucio, SB1
Sinhoreti, MA1
Correr-Sobrinho, L1
Puppin-Rontani, RM1
van Strijp, AJ1
Gerardu, VA1
Buijs, MJ1
van Loveren, C4
Cross, SE1
Kreth, J1
Wali, RP1
Shi, W2
Gimzewski, JK1
Nakata, K1
Nikaido, T1
Ikeda, M1
Foxton, RM1
Tagami, J1
Moron, BM2
Comar, LP2
Wiegand, A3
Buchalla, W2
Diamanti, I1
Koletsi-Kounari, H1
Mamai-Homata, E1
Vougiouklakis, G1
Hellen, A1
Mandelis, A1
Finer, Y1
Amaechi, BT1
Anderson, MH1
He, J1
Eckert, R1
Lynch, RJ3
Hara, AT1
González-Cabezas, C1
Jiang, H2
Fontana, M1
Eckert, G1
Zanarini, M1
Pazzi, E1
Bonetti, S1
Ruggeri, O1
Alessandri Bonetti, G1
Prati, C5
Schmidlin, PR4
Sener, B3
Attin, T1
Bhat, SS1
Hegde, SK1
Habibullah, MA1
Bernhardt, V1
Mohanty, B1
Dadlani, D1
Mahoney, D1
Mann, AB1
Yu, H1
Liu, L1
Yue, S1
Lu, T1
Chersoni, S1
Suppa, P1
Breschi, L2
Issa, AI1
Preston, KP1
Preston, AJ1
Toumba, KJ1
Duggal, MS1
Göhring, TN2
Zehnder, M2
Banerjee, A1
Gilmour, A1
Kidd, E1
Watson, T1
Kuramoto, A1
Imazato, S1
Walls, AW1
Ebisu, S1
Nucci, C2
Marchionni, S1
Piana, G1
Mazzoni, A1
Chang, WG1
Lim, BS1
Yoon, TH1
Lee, YK1
Kim, CW1
Zimmermann, MA1
Zimmermann, J1
Roos, M1
Roulet, JF1
Hong, SJ1
Jeong, SS1
Song, KB1
Takatsuka, T1
Tanaka, K1
Iijima, Y2
Mishra, P1
Palamara, JE1
Tyas, MJ1
Burrow, MF1
Krämer, N1
Kunzelmann, KH1
Häberlein, I1
Meier, B1
Frankenberger, R1
Gandolfi, MG1
Mongiorgi, R1
ZIPKIN, I1
McCLURE, FJ1
Yamazaki, H1
Margolis, HC6
Kinney, JH1
Balooch, M1
Haupt, DL1
Kleter, GA1
Damen, JJ2
Everts, V1
Niehof, J1
Tanaka, M1
Moreno, EC4
Zhang, YP3
van Houte, J1
Ruben, JL1
Zuidgeest, TG1
Arends, J1
Buijs, JF3
Spets-Happonen, S1
Luoma, H1
Seppä, L1
Räisänen, J1
Tagomori, S1
Iwase, T1
Lagerweij, MD1
Lee, CY1
Kent, RL2
Francci, C1
Deaton, TG1
Arnold, RR1
Swift, EJ1
Perdigão, J1
Bawden, JW1
McIntyre, JM1
Fu, J1
Tantbirojn, D1
Rozzi, SM1
Mitra, SB1
Kedrowski, BL1
Douglas, WH1
Yoshida, Y1
Van Meerbeek, B1
Nakayama, Y1
Yoshioka, M1
Snauwaert, J1
Abe, Y1
Lambrechts, P1
Vanherle, G1
Okazaki, M1
Kielbassa, AM1
Munz, I1
Bruggmoser, G1
Schulte-Mönting, J1
Wang, XY1
Miyazaki, K1
Itoh, Y1
Motokawa, W1
Lutz, F1
Savarino, L1
Saponara Teutonico, A1
Tarabusi, C1
Anderson, P1
Elliott, JC1
Kashket, S1
Yaskell, T1
Nammour, S1
Renneboog-Squilbin, C1
Nyssen-Behets, C1
Spitz, LM1
Eisenberg, AD1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of the Consumption of Beverages Added With Stevia Rebaudiana on Oral pH and Dental Biofilm in Adolescents[NCT05852145]Phase 1/Phase 252 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial.[NCT05437874]Phase 118 participants (Actual)Interventional2018-01-18Completed
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model[NCT01607411]Phase 355 participants (Actual)Interventional2012-02-29Completed
Comparison of Three Orthodontic Bonding Systems in White Spot Lesion Development: A Randomized Clinical Trial[NCT05738356]75 participants (Actual)Interventional2021-12-10Active, not recruiting
Comparison of the Remineralization Potential of an Optimized Fluoride Dentifrice With a Control Fluoride Dentifrice Using an in Situ Caries Model[NCT06010732]Phase 365 participants (Anticipated)Interventional2023-10-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

%SMHR of Enamel Specimens Exposed to Test Treatments

Surface microhardness recovery (SMHR) test was used to assess the changes in mineralization status of enamel specimens using a Wilson 2100 Hardness tester. SMHR was determined by measuring the length of the indentations of enamel specimens. An increase in the indentation length compared to the baseline indicates softening while decrease in the indentation length represents rehardening of enamel surface. Percent SMHR was calculated from indentation values of enamel specimens at baseline (B), after in-situ hardening (R) and after first demineralization challenge (D1) using formula: [(D1-R)/ (D1-B)]*100. (NCT01607411)
Timeframe: Baseline to 4 hours

Intervention%SMHR (Mean)
NaF Toothpaste (1426 Ppm F)30.72
NaF Toothpaste (1000 Ppm F)29.49
NaF Toothpaste (500 Ppm F)28.29

Enamel Fluoride Uptake

Enamel fluoride uptake was determined using the microdrill enamel biopsy technique. The amount of fluoride uptake by enamel was calculated based on amount of F divided by volume of the enamel cores and expressed as micrograms (μg)* F/centimeters(cm)^2. Difference between treatments was calculated with respect to F uptake by enamel. (NCT01607411)
Timeframe: Baseline to 4 hours

Interventionμg*F/cm^2 (Mean)
NaF Toothpaste (1426 Ppm F)1.76
NaF Toothpaste (1000 Ppm F)1.77
NaF Toothpaste (500 Ppm F)1.47
Placebo Toothpaste (0 Ppm F)0.98

Percent Net Acid Resistance (%NAR) of Enamel Specimens

Changes in mineral content of enamel specimens exposed to dietary erosive challenge were determined by measuring the length of the indentations. Decrease in the indentation length compared to the baseline indicates hardening of enamel surface. Enamel specimens were exposed to second erosion challenge to determine NAR which compared the indentations values of sound enamel specimens at baseline (B), first demineralization challenge (D1) and second demineralization challenge (D2). Percent NAR was calculated by formula: [(D1-D2)/ (D1-B)]*100. (NCT01607411)
Timeframe: Baseline to 4 hours

Intervention%NAR (Mean)
NaF Toothpaste (1426 Ppm F)-19.72
NaF Toothpaste (1000 Ppm F)-19.52
NaF Toothpaste (500 Ppm F)-25.82
Placebo Toothpaste (0 Ppm F)-54.38

Percentage Surface Microhardness Recovery of Test Dentifrices Relative to Placebo Dentifrice

Surface microhardness recovery (SMHR) test was used to assess the changes in mineralization status of enamel specimens using a Wilson 2100 Hardness tester. SMHR was determined by measuring the length of the indentations of enamel specimens. An increase in the indentation length compared to the baseline indicates softening while decrease in the indentation length represents rehardening of enamel surface. Percent SMHR was calculated from indentation values of enamel specimens at baseline (B), after in-situ hardening (R) and after first demineralization challenge (D1) using formula: [(D1-R)/ (D1-B)]*100. (NCT01607411)
Timeframe: Baseline to 4 hours

Intervention%SMHR (Mean)
NaF Toothpaste (1426 Ppm F)30.72
NaF Toothpaste (1000 Ppm F)29.49
NaF Toothpaste (500 Ppm F)28.29
Placebo Toothpaste (0 Ppm F)25.13

Trials

9 trials available for lactic acid and Demineralization, Tooth

ArticleYear
In situ clinical effects of new dentifrices containing 1.5% arginine and fluoride on enamel de- and remineralization and plaque metabolism.
    The Journal of clinical dentistry, 2013, Volume: 24 Spec no A

    Topics: Adolescent; Adult; Aged; Ammonium Compounds; Arginine; Calcium; Calcium Carbonate; Calcium Phosphate

2013
A randomised clinical study to evaluate experimental children's toothpastes in an in-situ palatal caries model in children aged 11-14 years.
    International dental journal, 2013, Volume: 63 Suppl 2

    Topics: Adolescent; Cariostatic Agents; Child; Cross-Over Studies; Dental Caries; Dental Enamel; Dose-Respon

2013
Staining of dentin from amalgam corrosion is induced by demineralization.
    American journal of dentistry, 2013, Volume: 26, Issue:4

    Topics: Cariogenic Agents; Copper; Corrosion; Dental Amalgam; Dentin; Humans; Hydrogen-Ion Concentration; La

2013
Chlorhexidine efficacy in preventing lesion formation in enamel and dentine: an in situ study.
    Caries research, 2008, Volume: 42, Issue:6

    Topics: Acids; Animals; Anti-Infective Agents, Local; Biofilms; Cariogenic Agents; Cariostatic Agents; Cattl

2008
In vitro evaluation of the effects of a fluoride-releasing composite on enamel demineralization around brackets.
    Progress in orthodontics, 2012, Volume: 13, Issue:1

    Topics: Acid Etching, Dental; Calcium; Cariogenic Agents; Cariostatic Agents; Composite Resins; Dental Bondi

2012
Resistance of marginal enamel to acid solubility is influenced by restorative systems: an in vitro scanning electron microscopic study.
    Clinical oral investigations, 2003, Volume: 7, Issue:2

    Topics: Adult; Cariogenic Agents; Compomers; Composite Resins; Dental Enamel; Dental Enamel Solubility; Dent

2003
A study investigating the formation of artificial sub-surface enamel caries-like lesions in deciduous and permanent teeth in the presence and absence of fluoride.
    Archives of oral biology, 2003, Volume: 48, Issue:8

    Topics: Cariogenic Agents; Dental Caries; Fluorides; Humans; Image Processing, Computer-Assisted; Lactic Aci

2003
Inhibition of dentine demineralization by zinc oxide: in vitro and in situ studies.
    Dental materials : official publication of the Academy of Dental Materials, 2005, Volume: 21, Issue:12

    Topics: Adult; Animals; Buffers; Cariostatic Agents; Cattle; Cross-Over Studies; Dentin; Double-Blind Method

2005
Effect of experimental fluoride-releasing tooth separator on acid resistance of human enamel in vitro.
    Dental materials journal, 2001, Volume: 20, Issue:4

    Topics: Absorptiometry, Photon; Analysis of Variance; Cariostatic Agents; Dental Enamel; Dental Enamel Solub

2001

Other Studies

81 other studies available for lactic acid and Demineralization, Tooth

ArticleYear
Remineralization and protection from demineralization: effects of a hydroxyapatite-containing, a fluoride-containing and a fluoride- and hydroxyapatite-free toothpaste on human enamel in vitro.
    Head & face medicine, 2022, Jul-13, Volume: 18, Issue:1

    Topics: Dental Enamel; Durapatite; Fluorides; Hardness; Humans; Lactic Acid; Tooth Demineralization; Tooth R

2022
Demonstration of an optical dentin hardness measuring device using bovine dentin with different demineralization times.
    Journal of biomedical optics, 2022, Volume: 27, Issue:10

    Topics: Animals; Cattle; Dental Caries; Dentin; Hardness; Lactic Acid; Optical Devices; Root Caries; Tooth D

2022
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel.
    Journal of oral science, 2023, Jan-11, Volume: 65, Issue:1

    Topics: Acetic Acid; Animals; Cattle; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Lactic Aci

2023
Can acid produced from probiotic bacteria alter the surface roughness, microhardness, and elemental composition of enamel? An in vitro study.
    Odontology, 2023, Volume: 111, Issue:4

    Topics: Bacteria; Calcium; Dental Enamel; Female; Fluorides; Hardness; Humans; Lactic Acid; Phosphorus; Prob

2023
Development and calibration of biochemical models for testing dental restorations.
    Acta biomaterialia, 2020, Volume: 109

    Topics: Animals; Biofilms; Calibration; Cattle; Composite Resins; Dental Restoration, Permanent; Hydrogen-Io

2020
Recovery after PILP remineralization of dentin lesions created with two cariogenic acids.
    Archives of oral biology, 2017, Volume: 82

    Topics: Acetates; Dentin; Elastic Modulus; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Atomic Forc

2017
Prognosis test by visualization of demineralized dentin under restorations to prevent initial wall-lesions initiated by lactic acid.
    American journal of dentistry, 2017, Volume: 30, Issue:3

    Topics: Bisphenol A-Glycidyl Methacrylate; Boron Compounds; Composite Resins; Dental Leakage; Dental Restora

2017
A comparative evaluation of APF gel, CPP/ACP paste alone and in combination with carbon dioxide laser on human enamel resistance to acid solubility using atomic absorption spectrometry: an in-vitro study.
    Minerva stomatologica, 2018, Volume: 67, Issue:2

    Topics: Acidulated Phosphate Fluoride; Bicuspid; Calcium; Caseins; Dental Enamel; Drug Evaluation, Preclinic

2018
Effectiveness of Vanish XT in Reducing the Development of White Spot Lesions: An In Vitro Study.
    Oral health & preventive dentistry, 2018, Volume: 16, Issue:4

    Topics: Humans; In Vitro Techniques; Lactic Acid; Light; Materials Testing; Microscopy, Fluorescence; Orthod

2018
Protective Effect of 4% Titanium Tetrafluoride Varnish on Dentin Demineralization Using a Microcosm Biofilm Model.
    Caries research, 2019, Volume: 53, Issue:5

    Topics: Animals; Biofilms; Cariostatic Agents; Cattle; Dentin; Fluorides; Fluorides, Topical; Humans; In Vit

2019
Effect of hydroalcoholic extract of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves on the viability and activity of microcosm biofilm and on enamel demineralization.
    Journal of applied oral science : revista FOB, 2019, May-30, Volume: 27

    Topics: Anacardiaceae; Animals; Anti-Infective Agents; Biofilms; Cariostatic Agents; Cattle; Colony Count, M

2019
Evaluation of a calcium phosphate desensitizer using an ultrasonic device.
    Dental materials journal, 2013, Volume: 32, Issue:3

    Topics: Analysis of Variance; Animals; Buffers; Calcium Phosphates; Cattle; Dental Cements; Dentin; Dentin D

2013
Fluoride dentifrice containing xylitol: in vitro root caries formation.
    American journal of dentistry, 2013, Volume: 26, Issue:1

    Topics: Cariostatic Agents; Dentifrices; Fluorides; Humans; Hydrogen-Ion Concentration; Lactic Acid; Materia

2013
Accelerated fatigue of dentin with exposure to lactic acid.
    Biomaterials, 2013, Volume: 34, Issue:34

    Topics: Adolescent; Adult; Dental Enamel; Dentin; Humans; Hydrogen-Ion Concentration; Lactic Acid; Microscop

2013
Numerical modelling of tooth enamel subsurface lesion formation induced by dental plaque.
    Caries research, 2014, Volume: 48, Issue:1

    Topics: Acid-Base Equilibrium; Algorithms; Cariostatic Agents; Dental Caries; Dental Enamel; Dental Enamel S

2014
Numerical modelling of tooth enamel subsurface lesion formation induced by dental plaque.
    Caries research, 2014, Volume: 48, Issue:1

    Topics: Acid-Base Equilibrium; Algorithms; Cariostatic Agents; Dental Caries; Dental Enamel; Dental Enamel S

2014
Numerical modelling of tooth enamel subsurface lesion formation induced by dental plaque.
    Caries research, 2014, Volume: 48, Issue:1

    Topics: Acid-Base Equilibrium; Algorithms; Cariostatic Agents; Dental Caries; Dental Enamel; Dental Enamel S

2014
Numerical modelling of tooth enamel subsurface lesion formation induced by dental plaque.
    Caries research, 2014, Volume: 48, Issue:1

    Topics: Acid-Base Equilibrium; Algorithms; Cariostatic Agents; Dental Caries; Dental Enamel; Dental Enamel S

2014
Inhibition of enamel demineralization by buffering effect of S-PRG filler-containing dental sealant.
    European journal of oral sciences, 2014, Volume: 122, Issue:1

    Topics: Aluminum; Animals; Barium; Buffers; Calcium; Cattle; Composite Resins; Dental Enamel; Durapatite; Fl

2014
Optical coherence tomography examination of the effect of S-PRG filler extraction solution on the demineralization of bovine enamel.
    Dental materials journal, 2014, Volume: 33, Issue:1

    Topics: Animals; Cattle; Coated Materials, Biocompatible; Dental Enamel; Glass Ionomer Cements; In Vitro Tec

2014
Does acid etching enhance remineralisation of arrested white spot lesions?
    European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2014, Volume: 15, Issue:6

    Topics: Acid Etching, Dental; Cariostatic Agents; Caseins; Dental Caries; Dental Enamel; Fluorescence; Fluor

2014
Enhanced enamel benefits from a novel toothpaste and dual phase gel containing calcium silicate and sodium phosphate salts.
    Journal of dentistry, 2014, Volume: 42 Suppl 1

    Topics: Animals; Calcium Compounds; Cariostatic Agents; Cattle; Citric Acid; Dental Enamel; Fluorides; Gels;

2014
Biofilm layers affect the treatment outcomes of NaF and Nano-hydroxyapatite.
    Journal of dental research, 2015, Volume: 94, Issue:4

    Topics: Animals; Bacterial Load; Biofilms; Calcium; Cariostatic Agents; Cattle; Dental Enamel; Durapatite; F

2015
Effect of three different pastes on remineralization of initial enamel lesion: an in vitro study.
    The Journal of clinical pediatric dentistry, 2015,Winter, Volume: 39, Issue:2

    Topics: Cariostatic Agents; Caseins; Crystallization; Dental Enamel; Durapatite; Hardness; Humans; Hydrogen-

2015
In vitro Induction of residual caries lesions in dentin: comparative mineral loss and nano-hardness analysis.
    Caries research, 2015, Volume: 49, Issue:3

    Topics: Acetic Acid; Biofilms; Citric Acid; Dental Caries; Dentin; Diphosphonates; Edetic Acid; Elastic Modu

2015
Inhibition of enamel demineralization and bond-strength properties of bioactive glass containing 4-META/MMA-TBB-based resin adhesive.
    European journal of oral sciences, 2015, Volume: 123, Issue:3

    Topics: Boron; Boron Compounds; Buffers; Calcium; Ceramics; Dental Bonding; Dental Enamel; Glass; Hardness;

2015
Ultrasonic assessment of the effects of self-assembling peptide scaffolds on preventing enamel demineralization.
    Acta odontologica Scandinavica, 2016, Volume: 74, Issue:2

    Topics: Animals; Buffers; Cattle; Dental Enamel; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Confoc

2016
Identification of acid-resistant proteins in acquired enamel pellicle.
    Journal of dentistry, 2015, Volume: 43, Issue:12

    Topics: Adolescent; Adult; Citric Acid; Cross-Over Studies; Cystatin B; Dental Caries; Dental Enamel; Dental

2015
Distinct decalcification process of dentin by different cariogenic organic acids: Kinetics, ultrastructure and mechanical properties.
    Archives of oral biology, 2016, Volume: 63

    Topics: Acetates; Biomechanical Phenomena; Dentin; Elastic Modulus; Hardness; Humans; Hydrogen-Ion Concentra

2016
Enamel Surface with Pit and Fissure Sealant Containing 45S5 Bioactive Glass.
    Journal of dental research, 2016, Volume: 95, Issue:5

    Topics: Animals; Bisphenol A-Glycidyl Methacrylate; Cariogenic Agents; Cattle; Ceramics; Composite Resins; D

2016
Proanthocyanidins-Loaded Nanoparticles Enhance Dentin Degradation Resistance.
    Journal of dental research, 2017, Volume: 96, Issue:7

    Topics: Adult; Collagenases; Composite Resins; Dentin; Dentin-Bonding Agents; Grape Seed Extract; Humans; Hy

2017
Confocal laser scanning microscopic analysis of the depth of dentin caries-like lesions in primary and permanent teeth.
    Brazilian dental journal, 2008, Volume: 19, Issue:2

    Topics: Bacteriological Techniques; Bicuspid; Carboxymethylcellulose Sodium; Dental Caries; Dentin; Gels; Hu

2008
Evaluation of bacteria-induced enamel demineralization using optical profilometry.
    Dental materials : official publication of the Academy of Dental Materials, 2009, Volume: 25, Issue:12

    Topics: Algorithms; Animals; Biofilms; Cattle; Citric Acid; Dental Enamel; Hydrogen-Ion Concentration; Imagi

2009
Relationship between fluorescence loss of QLF and depth of demineralization in an enamel erosion model.
    Dental materials journal, 2009, Volume: 28, Issue:5

    Topics: Analysis of Variance; Animals; Cattle; Dental Caries; Dental Caries Activity Tests; Dental Enamel; D

2009
Comparison of cross-sectional hardness and transverse microradiography of artificial carious enamel lesions induced by different demineralising solutions and gels.
    Caries research, 2009, Volume: 43, Issue:6

    Topics: Acetates; Acrylic Resins; Anatomy, Cross-Sectional; Animals; Apatites; Buffers; Calcium Phosphates;

2009
In vitro evaluation of fluoride and calcium sodium phosphosilicate toothpastes, on root dentine caries lesions.
    Journal of dentistry, 2011, Volume: 39, Issue:9

    Topics: Animals; Cariogenic Agents; Cariostatic Agents; Cattle; Dentin; Dentin Solubility; Glass; Hardness;

2011
Quantitative remineralization evolution kinetics of artificially demineralized human enamel using photothermal radiometry and modulated luminescence.
    Journal of biophotonics, 2011, Volume: 4, Issue:11-12

    Topics: Computer Simulation; Dental Enamel; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetic

2011
Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization.
    Caries research, 2011, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacterial

2011
Effect of fluoride, lesion baseline severity and mineral distribution on lesion progression.
    Caries research, 2012, Volume: 46, Issue:1

    Topics: Acetic Acid; Animals; Apatites; Calcium Fluoride; Calcium Phosphates; Carboxymethylcellulose Sodium;

2012
Effect of low pH on surface rehardening efficacy of high concentration fluoride treatments on non-cavitated lesions.
    Journal of dentistry, 2012, Volume: 40, Issue:6

    Topics: Cariostatic Agents; Dental Enamel; Dental Pellicle; Hardness; Humans; Hydrogen-Ion Concentration; La

2012
Protection of sound enamel and artificial enamel lesions against demineralisation: caries infiltrant versus adhesive.
    Journal of dentistry, 2012, Volume: 40, Issue:10

    Topics: Acrylates; Animals; Apatites; Cattle; Composite Resins; Dental Caries; Dental Enamel; Dental Enamel

2012
The effects of lesion baseline characteristics and different Sr:Ca ratios in plaque fluid-like solutions on caries lesion de- and remineralization.
    Archives of oral biology, 2012, Volume: 57, Issue:10

    Topics: Analysis of Variance; Animals; Calcium Chloride; Cattle; Dental Caries; Dental Plaque; In Vitro Tech

2012
Incipient enamel lesions remineralization using casein phosphopeptide amorphous calcium phosphate cream with and without fluoride: a laser fluorescence study.
    The Journal of clinical pediatric dentistry, 2012,Summer, Volume: 36, Issue:4

    Topics: Cariostatic Agents; Caseins; Dental Enamel; Fluorescence; Fluorides; Humans; Hydrogen-Ion Concentrat

2012
Characterizing and identifying incipient carious lesions in dental enamel using micro-Raman spectroscopy.
    Caries research, 2013, Volume: 47, Issue:1

    Topics: Carbonates; Cariogenic Agents; Dental Caries; Dental Enamel; Dentin; Humans; Hydrogen-Ion Concentrat

2013
Characteristics of methylcellulose acid gel lesions created in human and bovine enamel.
    Caries research, 2013, Volume: 47, Issue:1

    Topics: Animals; Cattle; Dental Caries; Dental Enamel; Dentin; Humans; Hydrogen-Ion Concentration; Lactic Ac

2013
Different protocols to produce artificial dentine carious lesions in vitro and in situ: hardness and mineral content correlation.
    Caries research, 2013, Volume: 47, Issue:2

    Topics: Acetic Acid; Anatomy, Cross-Sectional; Animals; Biofilms; Buffers; Calcium; Carboxymethylcellulose S

2013
[Comparison of demineralization of different organic acid to enamel].
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 1998, Volume: 16, Issue:2

    Topics: Acetic Acid; Dental Caries; Dental Enamel; Dental Enamel Solubility; Dental Plaque; Formates; Humans

1998
In vitro microleakage of adhesive-sealed dentin with lactic acid and saliva exposure: a radio-isotope analysis.
    Journal of dentistry, 2004, Volume: 32, Issue:3

    Topics: Acid Etching, Dental; Acrylates; Analysis of Variance; Composite Resins; Dental Cavity Lining; Denta

2004
Relationship between S. mutans and the autofluorescence of carious dentin.
    American journal of dentistry, 2004, Volume: 17, Issue:4

    Topics: Bicuspid; Chelating Agents; Dental Caries; Dentin; Edetic Acid; Fluorescence; Humans; Lactic Acid; M

2004
Inhibition of root caries progression by an antibacterial adhesive.
    Journal of dental research, 2005, Volume: 84, Issue:1

    Topics: Acetone; Adhesives; Analysis of Variance; Anti-Infective Agents, Local; Bisphenol A-Glycidyl Methacr

2005
Morphological evaluation of enamel surface after application of two 'home' whitening products.
    Oral health & preventive dentistry, 2004, Volume: 2, Issue:3

    Topics: Carbamide Peroxide; Cariogenic Agents; Dental Enamel; Drug Combinations; Humans; Hydrogen Peroxide;

2004
Effects of salicylic-lactic acid conditioner on the shear bond strength of brackets and enamel surfaces.
    Journal of oral rehabilitation, 2005, Volume: 32, Issue:4

    Topics: Acid Etching, Dental; Bicuspid; Composite Resins; Dental Bonding; Dental Enamel; Humans; Lactic Acid

2005
Sealing smooth enamel surfaces with a newly devised adhesive patch: a radiochemical in vitro analysis.
    Dental materials : official publication of the Academy of Dental Materials, 2005, Volume: 21, Issue:6

    Topics: Acrylates; Adhesives; Analysis of Variance; Animals; Cattle; Dental Enamel; Dental Stress Analysis;

2005
Effects of sanguinaria in fluoride-containing dentifrices on the remineralisation of subsurface carious lesion in vitro.
    International dental journal, 2005, Volume: 55, Issue:3

    Topics: Alkaloids; Animals; Benzophenanthridines; Cariostatic Agents; Cattle; Dental Caries; Dental Enamel;

2005
The effect of adjacent dentine blocks on the demineralisation and remineralisation of enamel in vitro.
    Caries research, 2006, Volume: 40, Issue:1

    Topics: Analysis of Variance; Animals; Calcium Phosphates; Cattle; Dental Enamel; Dental Enamel Solubility;

2006
Effect of loading and pH on the subsurface demineralization of dentin beams.
    Calcified tissue international, 2006, Volume: 79, Issue:4

    Topics: Animals; Biomechanical Phenomena; Cattle; Dentin; Hydrogen-Ion Concentration; Lactic Acid; Pressure;

2006
Determination of caries risk at resin composite margins.
    American journal of dentistry, 2007, Volume: 20, Issue:1

    Topics: Composite Resins; Dental Caries; Dental Caries Susceptibility; Dental Enamel; Dental Impression Mate

2007
Dental enamel dissolution after alendronate treatment.
    American journal of dentistry, 2007, Volume: 20, Issue:4

    Topics: Bone Density Conservation Agents; Dental Enamel; Diphosphonates; Humans; Hydrogen-Ion Concentration;

2007
Inhibitory effect of fluoride on tooth decalcification by citrate and lactate in vivo.
    Journal of dental research, 1949, Volume: 28, Issue:2

    Topics: Citrates; Citric Acid; Dental Caries; Fluorides; Humans; Lactic Acid; Phosphates; Tooth; Tooth Demin

1949
Enhanced enamel remineralization under acidic conditions in vitro.
    Journal of dental research, 2008, Volume: 87, Issue:6

    Topics: Calcium Phosphates; Dental Enamel; Dental Enamel Solubility; Fluorides; Humans; Ions; Lactic Acid; S

2008
Mineral distribution and dimensional changes in human dentin during demineralization.
    Journal of dental research, 1995, Volume: 74, Issue:5

    Topics: Acid Etching, Dental; Collagen; Dentin; Desiccation; Humans; Lactates; Lactic Acid; Microscopy, Atom

1995
The influence of the organic matrix on demineralization of bovine root dentin in vitro.
    Journal of dental research, 1994, Volume: 73, Issue:9

    Topics: Acetates; Acetic Acid; Animals; Buffers; Calcium; Cattle; Collagenases; Dentin; Diphosphonates; Hydr

1994
Effect of fluoride incorporation into human dental enamel on its demineralization in vitro.
    Archives of oral biology, 1993, Volume: 38, Issue:10

    Topics: Buffers; Calcium; Densitometry; Dental Caries; Dental Enamel; Dental Enamel Solubility; Fluorides; H

1993
Effect of sucrose concentration on the cariogenic potential of pooled plaque fluid from caries-free and caries-positive individuals.
    Caries research, 1993, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Dental Caries; Dental Plaque; Humans; Lactates; Lactic Acid; Middle Aged; Strepto

1993
Fluoride and mineral content in hyper-remineralized coronal bovine dentine in vitro after an acid challenge.
    Caries research, 1993, Volume: 27, Issue:2

    Topics: Animals; Calcium Chloride; Cattle; Dentin; Fluorides; Lactates; Lactic Acid; Mass Spectrometry; Micr

1993
Protective effect of topically applied fluoride in relation to fluoride sensitivity of mutans streptococci.
    Journal of dental research, 1993, Volume: 72, Issue:8

    Topics: Adaptation, Biological; Analysis of Variance; Animals; Calcium; Cattle; Dental Caries; Dental Plaque

1993
The effect of different strontium concentrations on the efficacy of chlorhexidine-fluoride-strontium gel in preventing enamel softening in vitro.
    Archives of oral biology, 1993, Volume: 38, Issue:2

    Topics: Administration, Topical; Animals; Calcium; Cattle; Chlorhexidine; Dental Enamel; Dental Enamel Solub

1993
Ultrastructural change of enamel exposed to a normal pulsed Nd-YAG laser.
    Caries research, 1995, Volume: 29, Issue:6

    Topics: Crystallization; Dental Enamel; Dental Enamel Solubility; Dose-Response Relationship, Radiation; Har

1995
Demineralization of dentine grooves in vitro.
    Caries research, 1996, Volume: 30, Issue:3

    Topics: Analysis of Variance; Animals; Cariogenic Agents; Cattle; Composite Resins; Dental Fissures; Dental

1996
Protection of dentin by triclosan toothpaste in a bacterial demineralisation model.
    European journal of oral sciences, 1999, Volume: 107, Issue:2

    Topics: Adsorption; Analysis of Variance; Animals; Cattle; Dentin; Lactic Acid; Statistics, Nonparametric; S

1999
Kinetics of enamel demineralization in vitro.
    Journal of dental research, 1999, Volume: 78, Issue:7

    Topics: Acetates; Algorithms; Calcium; Dental Enamel; Dental Enamel Solubility; Dental Plaque; Durapatite; H

1999
Fluoride release from restorative materials and its effects on dentin demineralization.
    Journal of dental research, 1999, Volume: 78, Issue:10

    Topics: Animals; Cattle; Dental Materials; Dental Restoration, Permanent; Dentin; Fluorides; Hydrogen-Ion Co

1999
Studies of dental root surface caries. 1: Comparison of natural and artificial root caries lesions.
    Australian dental journal, 2000, Volume: 45, Issue:1

    Topics: Acetic Acid; Buffers; Hardness; Humans; Immersion; Lactic Acid; Microscopy, Polarization; Minerals;

2000
Enamel demineralization under driving forces found in dental plaque fluid.
    European journal of oral sciences, 2000, Volume: 108, Issue:3

    Topics: Cariogenic Agents; Dental Caries; Dental Enamel Solubility; Dental Plaque; Dose-Response Relationshi

2000
In vitro inhibition of enamel demineralization by a polymerizable amphiphilic film.
    European journal of oral sciences, 2000, Volume: 108, Issue:6

    Topics: Acrylates; Animals; Cariostatic Agents; Cattle; Dental Enamel; Dimethylpolysiloxanes; Disease Models

2000
Adhesion to and decalcification of hydroxyapatite by carboxylic acids.
    Journal of dental research, 2001, Volume: 80, Issue:6

    Topics: Acrylic Resins; Adhesiveness; Adsorption; Calcium; Calcium Citrate; Calcium Compounds; Calcium Oxala

2001
Effect of demineralization and remineralization on microhardness of irradiated dentin.
    The Journal of clinical dentistry, 2002, Volume: 13, Issue:3

    Topics: Amines; Analysis of Variance; Animals; Cariostatic Agents; Cattle; Cellulose; Dentin; Diamines; Fluo

2002
Resistance of an enamel-bonding agent to saliva and acid exposure in vitro assessed by liquid scintillation.
    Dental materials : official publication of the Academy of Dental Materials, 2002, Volume: 18, Issue:4

    Topics: Acrylates; Animals; Cattle; Composite Resins; Dental Enamel; Dental Enamel Solubility; Dental Leakag

2002
Enamel microhardness after in vitro demineralization and role of different restorative materials.
    Journal of biomaterials science. Polymer edition, 2002, Volume: 13, Issue:3

    Topics: Biomechanical Phenomena; Dental Caries; Dental Enamel; Humans; Lactic Acid; Models, Biological; Mola

2002
Subsurface demineralization in dental enamel and other permeable solids during acid dissolution.
    Journal of dental research, 1992, Volume: 71, Issue:8

    Topics: Acetates; Acetic Acid; Barium Compounds; Calcium Hydroxide; Dental Enamel; Dental Enamel Solubility;

1992
Composition of pooled plaque fluid from caries-free and caries-positive individuals following sucrose exposure.
    Journal of dental research, 1992, Volume: 71, Issue:11

    Topics: Adolescent; Adult; Calcium; Child; Dental Caries; Dental Plaque; Fluorides; Humans; Hydrogen-Ion Con

1992
Effect of timing of administered calcium lactate on the sucrose-induced intraoral demineralization of bovine enamel.
    Archives of oral biology, 1992, Volume: 37, Issue:3

    Topics: Adult; Animals; Calcium; Cattle; Dental Enamel; Dental Enamel Solubility; Dental Plaque; Female; Hum

1992
Increased resistance to artificial caries-like lesions in dentin treated with CO2 laser.
    Caries research, 1992, Volume: 26, Issue:3

    Topics: Carbon Dioxide; Densitometry; Dental Caries; Dentin; Humans; Lactates; Lactic Acid; Laser Therapy; M

1992
In vitro demineralization of enamel by F-sensitive and F-resistant mutans streptococci in the presence of 0, 0.05, or 0.5 mmol/L NaF.
    Journal of dental research, 1991, Volume: 70, Issue:12

    Topics: Animals; Cattle; Dental Enamel; Dental Plaque; Drug Resistance, Microbial; Glucose; Hydrogen-Ion Con

1991