lactic acid has been researched along with Decreased Muscle Tone in 13 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Lactic acidosis is exceptionally associated to this allergy." | 7.70 | [Severe lactic acidosis disease disclosing milk-protein intolerance to cows' milk]. ( Ogier de Baulny, H; Olivier, C; Rizk, C; Saudubray, JM; Valdes, L, 1999) |
| " Among them, there were 19 cases of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS), 2 cases of encephalopathies which could not be classified into any specific type, 2 cases of floppy infants, one case of Kearns-Sayer syndrome (KSS) and one case of mitochondrial entero-myopathy." | 3.73 | [Phenotype heterogeneity associated with mitochondrial DNA A3243G mutation]. ( Niu, SL; Pei, P; Qi, Y; Wang, ZX; Xu, YF; Yang, YL; Yuan, Y; Zhang, Y, 2005) |
| " Lactic acidosis is exceptionally associated to this allergy." | 3.70 | [Severe lactic acidosis disease disclosing milk-protein intolerance to cows' milk]. ( Ogier de Baulny, H; Olivier, C; Rizk, C; Saudubray, JM; Valdes, L, 1999) |
| "Three bedouin children with mitochondrial myopathy due to cytochrome c oxidase deficiency presented with progressive muscle weakness, failure to thrive, proximal renal tubular acidosis, and lactic acidemia leading to death." | 3.68 | Autosomal recessive lethal infantile cytochrome C oxidase deficiency. ( Aladjem, M; Barash, V; Barr, J; DiMauro, S; Eshel, G; Fried, K; Gutman, A; Lahat, E, 1991) |
| "Alexander disease is a neurodegenerative disorder characterized by macrocephaly and progressive demyelination with frontal lobe preponderance." | 1.33 | Early mitochondrial dysfunction in an infant with Alexander disease. ( Cáceres-Marzal, C; Fernández, S; Galán, E; Vaquerizo, J, 2006) |
| "The lack of cobalamin caused a severe encephalopathy in the infant, whose brain displayed a striking loss of volume and a delay of myelination." | 1.32 | Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion. ( Horstmann, M; Kohlschütter, A; Lukacs, Z; Neumaier-Probst, E; Steinfeld, R; Ullrich, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verity, CM | 1 |
| Winstone, AM | 1 |
| Stellitano, L | 1 |
| Krishnakumar, D | 1 |
| Will, R | 1 |
| McFarland, R | 1 |
| Szklarczyk, R | 1 |
| Wanschers, BF | 1 |
| Nijtmans, LG | 2 |
| Rodenburg, RJ | 1 |
| Zschocke, J | 1 |
| Dikow, N | 1 |
| van den Brand, MA | 1 |
| Hendriks-Franssen, MG | 1 |
| Gilissen, C | 1 |
| Veltman, JA | 1 |
| Nooteboom, M | 1 |
| Koopman, WJ | 1 |
| Willems, PH | 1 |
| Smeitink, JA | 1 |
| Huynen, MA | 1 |
| van den Heuvel, LP | 1 |
| Horstmann, M | 1 |
| Neumaier-Probst, E | 1 |
| Lukacs, Z | 1 |
| Steinfeld, R | 1 |
| Ullrich, K | 1 |
| Kohlschütter, A | 1 |
| Zhang, Y | 1 |
| Wang, ZX | 1 |
| Niu, SL | 1 |
| Xu, YF | 1 |
| Pei, P | 1 |
| Yuan, Y | 1 |
| Yang, YL | 1 |
| Qi, Y | 1 |
| Cáceres-Marzal, C | 1 |
| Vaquerizo, J | 1 |
| Galán, E | 1 |
| Fernández, S | 1 |
| Gabreëls, FJ | 1 |
| Prick, MJ | 1 |
| Trijbels, JM | 1 |
| Renier, WO | 1 |
| Jaspar, HH | 1 |
| Janssen, AJ | 1 |
| Slooff, JL | 1 |
| Simmons, RD | 1 |
| Bernard, CC | 1 |
| Kerlero de Rosbo, N | 1 |
| Carnegie, PR | 1 |
| Lincke, CR | 1 |
| van den Bogert, C | 1 |
| Wanders, RJ | 1 |
| Tamminga, P | 1 |
| Barth, PG | 1 |
| Sewell, AC | 1 |
| Sperl, W | 1 |
| Herwig, J | 1 |
| Böhles, HJ | 1 |
| Rizk, C | 1 |
| Valdes, L | 1 |
| Ogier de Baulny, H | 1 |
| Saudubray, JM | 1 |
| Olivier, C | 1 |
| Lu, FL | 1 |
| Wang, PJ | 1 |
| Hwu, WL | 1 |
| Tsou Yau, KI | 1 |
| Wang, TR | 1 |
| Eshel, G | 1 |
| Lahat, E | 1 |
| Fried, K | 1 |
| Barr, J | 1 |
| Barash, V | 1 |
| Gutman, A | 1 |
| DiMauro, S | 1 |
| Aladjem, M | 1 |
| Torbergsen, T | 1 |
| Aasly, J | 1 |
| Borud, O | 1 |
| Lindal, S | 1 |
| Mellgren, SI | 1 |
13 other studies available for lactic acid and Decreased Muscle Tone
| Article | Year |
|---|---|
The clinical presentation of mitochondrial diseases in children with progressive intellectual and neurological deterioration: a national, prospective, population-based study.
Topics: Adolescent; Basal Ganglia; Child; Child, Preschool; Developmental Disabilities; Diagnosis, Different | 2010 |
A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia.
Topics: Abnormalities, Multiple; Amino Acid Sequence; Animals; Ataxia; Base Sequence; Cells, Cultured; Child | 2013 |
Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.
Topics: Brain Diseases; Choline Deficiency; Humans; Infant; Lactic Acid; Magnetic Resonance Spectroscopy; Ma | 2003 |
[Phenotype heterogeneity associated with mitochondrial DNA A3243G mutation].
Topics: Adolescent; Adult; Child; Child, Preschool; DNA, Mitochondrial; Female; Humans; Infant; Kearns-Sayre | 2005 |
Early mitochondrial dysfunction in an infant with Alexander disease.
Topics: Alexander Disease; Biopsy; Brain; Cytochrome-c Oxidase Deficiency; Diagnosis, Differential; Female; | 2006 |
Defects in citric acid cycle and the electron transport chain in progressive poliodystrophy.
Topics: Adolescent; Brain; Carbon Dioxide; Child; Child, Preschool; Citric Acid Cycle; Electron Transport; F | 1984 |
Criteria for an adequate explanation of typical clinical signs of EAE in rodents.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Hindlimb; Lactates; Lactic Acid; Muscle Hypoto | 1984 |
Cerebellar hypoplasia in respiratory chain dysfunction.
Topics: Cerebellum; Consanguinity; Cytochrome-c Oxidase Deficiency; Fatal Outcome; Female; Humans; Infant, N | 1996 |
Cirrhosis in a child with deficiency of mitochondrial respiratory-chain succinate-cytochrome c-oxidoreductase.
Topics: Electron Transport Complex II; Electron Transport Complex III; Epilepsy, Tonic-Clonic; Fatal Outcome | 1997 |
[Severe lactic acidosis disease disclosing milk-protein intolerance to cows' milk].
Topics: Acidosis, Lactic; Animals; Fasting; Female; Humans; Infant; Lactic Acid; Milk; Milk Hypersensitivity | 1999 |
Neonatal type of nonketotic hyperglycinemia.
Topics: Ammonia; Brain; Female; Glycine; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; M | 1999 |
Autosomal recessive lethal infantile cytochrome C oxidase deficiency.
Topics: Acidosis, Renal Tubular; Child, Preschool; Consanguinity; Cytochrome-c Oxidase Deficiency; Electron | 1991 |
Mitochondrial myopathy in Marinesco-Sjögren syndrome.
Topics: Adolescent; Adult; Biopsy; Cerebellum; Chromosome Aberrations; Chromosome Disorders; Exercise Test; | 1991 |