lactic acid has been researched along with Cytomegalovirus Retinitis in 5 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Cytomegalovirus Retinitis: Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in AIDS patients and can cause blindness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of a biodegradable scleral plug containing ganciclovir (GCV) in a rabbit model of human cytomegalovirus (HCMV) retinitis." | 7.71 | Scleral plug of biodegradable polymers containing ganciclovir for experimental cytomegalovirus retinitis. ( Kunou, N; Matsuda, Y; Nakajima, K; Ogura, Y; Ozeki, H; Sakurai, E, 2001) |
| "To test the antiviral effect of ganciclovir released from biodegradable polymer microspheres in rabbit eyes inoculated with human cytomegalovirus (HCMV)." | 7.69 | Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus. ( Herrero-Vanrell, R; Refojo, MF; Veloso, AA; Zhu, Q, 1997) |
| " In this context, the aim of this study was to design in situ thermosensitive hydrogels for GCV ocular delivery by intravitreal injection to achieve sustained drug release behavior and improved ocular bioavailability in the treatment of CMV retinitis." | 5.48 | Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment. ( Shen, Y; Sun, C; Tu, J; Wang, Q; Xu, B, 2018) |
| "To evaluate the efficacy of a biodegradable scleral plug containing ganciclovir (GCV) in a rabbit model of human cytomegalovirus (HCMV) retinitis." | 3.71 | Scleral plug of biodegradable polymers containing ganciclovir for experimental cytomegalovirus retinitis. ( Kunou, N; Matsuda, Y; Nakajima, K; Ogura, Y; Ozeki, H; Sakurai, E, 2001) |
| "To test the antiviral effect of ganciclovir released from biodegradable polymer microspheres in rabbit eyes inoculated with human cytomegalovirus (HCMV)." | 3.69 | Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus. ( Herrero-Vanrell, R; Refojo, MF; Veloso, AA; Zhu, Q, 1997) |
| "The plugs are effective for treating vitreoretinal diseases such as proliferative vitreoretinopathy." | 2.41 | Biodegradable scleral plugs for vitreoretinal drug delivery. ( Kimura, H; Ogura, Y; Tabata, Y; Yasukawa, T, 2001) |
| " In this context, the aim of this study was to design in situ thermosensitive hydrogels for GCV ocular delivery by intravitreal injection to achieve sustained drug release behavior and improved ocular bioavailability in the treatment of CMV retinitis." | 1.48 | Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment. ( Shen, Y; Sun, C; Tu, J; Wang, Q; Xu, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Sun, C | 1 |
| Xu, B | 1 |
| Tu, J | 1 |
| Shen, Y | 1 |
| Duvvuri, S | 1 |
| Janoria, KG | 1 |
| Pal, D | 1 |
| Mitra, AK | 1 |
| Veloso, AA | 1 |
| Zhu, Q | 1 |
| Herrero-Vanrell, R | 1 |
| Refojo, MF | 1 |
| Sakurai, E | 1 |
| Matsuda, Y | 1 |
| Ozeki, H | 1 |
| Kunou, N | 1 |
| Nakajima, K | 1 |
| Ogura, Y | 2 |
| Yasukawa, T | 1 |
| Kimura, H | 1 |
| Tabata, Y | 1 |
1 review available for lactic acid and Cytomegalovirus Retinitis
| Article | Year |
|---|---|
Biodegradable scleral plugs for vitreoretinal drug delivery.
Topics: Animals; Biodegradation, Environmental; Cytomegalovirus Retinitis; Drug Delivery Systems; Eye Diseas | 2001 |
4 other studies available for lactic acid and Cytomegalovirus Retinitis
| Article | Year |
|---|---|
Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment.
Topics: 4-Butyrolactone; Animals; Antiviral Agents; Aqueous Humor; Area Under Curve; Biocompatible Materials | 2018 |
Controlled delivery of ganciclovir to the retina with drug-loaded Poly(d,L-lactide-co-glycolide) (PLGA) microspheres dispersed in PLGA-PEG-PLGA Gel: a novel intravitreal delivery system for the treatment of cytomegalovirus retinitis.
Topics: Animals; Antiviral Agents; Chemistry, Pharmaceutical; Cytomegalovirus Retinitis; Delayed-Action Prep | 2007 |
Ganciclovir-loaded polymer microspheres in rabbit eyes inoculated with human cytomegalovirus.
Topics: Animals; Antigens, Viral; Biocompatible Materials; Biodegradation, Environmental; Cytomegalovirus; C | 1997 |
Scleral plug of biodegradable polymers containing ganciclovir for experimental cytomegalovirus retinitis.
Topics: Absorbable Implants; Animals; Antigens, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Re | 2001 |