lactic acid has been researched along with Cystic Periventricular Leukomalacia in 4 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyruvate dehydrogenase (PDH) deficiency is a major cause of primary lactic acidosis and neurological dysfunction in infancy and early childhood." | 3.78 | Unilateral periventricular leukomalacia in association with pyruvate dehydrogenase deficiency. ( Connolly, DJ; Mordekar, SR; Sharma, R; Sharrard, MJ, 2012) |
| "Preoperative MRI examinations showed periventricular leukomalacia (PVL) in 4 patients (16%) and infarct in 2 subjects (8%)." | 2.70 | An MRI study of neurological injury before and after congenital heart surgery. ( Chiavacci, RM; Clancy, RR; Galli, KK; Gaynor, JW; Kurth, CD; Mahle, WT; Montenegro, LM; Nicolson, SC; Spray, TL; Tavani, F; Wernovsky, G; Zimmerman, RA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nadeem, M | 1 |
| Clarke, A | 1 |
| Dempsey, EM | 1 |
| Sharma, R | 1 |
| Sharrard, MJ | 1 |
| Connolly, DJ | 1 |
| Mordekar, SR | 1 |
| Mahle, WT | 1 |
| Tavani, F | 1 |
| Zimmerman, RA | 1 |
| Nicolson, SC | 1 |
| Galli, KK | 1 |
| Gaynor, JW | 1 |
| Clancy, RR | 1 |
| Montenegro, LM | 1 |
| Spray, TL | 1 |
| Chiavacci, RM | 1 |
| Wernovsky, G | 1 |
| Kurth, CD | 1 |
| Kidokoro, H | 1 |
| Shimizu, M | 1 |
| Kimoto, H | 1 |
| Okumura, A | 1 |
| Hayakawa, M | 1 |
| Watanabe, K | 1 |
| Ohno, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Anatomy, Hemodynamics and Metabolism In Single Ventricles: Relationship to Neurodevelopment[NCT02919956] | 119 participants (Actual) | Observational | 2016-04-30 | Active, not recruiting | |||
| International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery[NCT05673499] | 900 participants (Anticipated) | Observational | 2022-08-12 | Recruiting | |||
| Autologous Cord Blood Cells for Patients With HLHS: Phase I Study of Feasibility and Safety[NCT01445041] | Phase 1 | 7 participants (Actual) | Interventional | 2011-09-01 | Terminated (stopped due to Funding Period Ended) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lactic acid and Cystic Periventricular Leukomalacia
| Article | Year |
|---|---|
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
An MRI study of neurological injury before and after congenital heart surgery.
Topics: Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebral Infarction; Cerebrovascular Disorders; Coho | 2002 |
3 other studies available for lactic acid and Cystic Periventricular Leukomalacia
| Article | Year |
|---|---|
Day 1 serum lactate values in preterm infants less than 32 weeks gestation.
Topics: Acid-Base Imbalance; Biomarkers; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth | 2010 |
Unilateral periventricular leukomalacia in association with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Alleles; Cerebral Ventricles; Developmental Disabilities; Diagnosis, Differential; | 2012 |
Relationship between serum lactate level and periventricular leukomalacia.
Topics: Case-Control Studies; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, P | 2007 |