lactic acid has been researched along with Cryptogenic Fibrosing Alveolitis in 10 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lactic acid and LDH5 were significantly elevated in IPF lung tissue compared with controls." | 5.38 | Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β. ( Dahanayake, T; Grant, G; Honnons, S; Hu, JZ; Isern, NG; Jones, C; Kottmann, RM; Kulkarni, AA; Lyda, E; Nathan, SD; Phipps, RP; Salibi, R; Sime, PJ; Smolnycki, KA, 2012) |
| "Radiation-induced lung injury (RILI) is a consequence of therapeutic thoracic irradiation (TR) for many cancers, and there are no FDA-approved curative strategies." | 1.91 | Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury. ( Allegood, JC; Camus, SV; Cowart, LA; Freeberg, MAT; Jackson, PD; Liu, J; Pierre-Louis Odoom, J; Sanchez Rosado, RM; Silvey, S; Sime, PJ; Szomju, BB; Thatcher, TH; Toft, R; Weiss, E, 2023) |
| "Idiopathic pulmonary fibrosis is a progressive, fatal lung disease with poor survival." | 1.46 | Spermidine-mediated poly(lactic- ( Ding, J; Li, D; Li, G; Li, J; Tang, J; Wang, L; Zhang, H, 2017) |
| "Lactic acid and LDH5 were significantly elevated in IPF lung tissue compared with controls." | 1.38 | Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β. ( Dahanayake, T; Grant, G; Honnons, S; Hu, JZ; Isern, NG; Jones, C; Kottmann, RM; Kulkarni, AA; Lyda, E; Nathan, SD; Phipps, RP; Salibi, R; Sime, PJ; Smolnycki, KA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Newton, DA | 1 |
| Lottes, RG | 1 |
| Ryan, RM | 1 |
| Spyropoulos, DD | 1 |
| Baatz, JE | 1 |
| Yang, L | 1 |
| Gilbertsen, A | 1 |
| Xia, H | 1 |
| Benyumov, A | 1 |
| Smith, K | 1 |
| Herrera, J | 1 |
| Racila, E | 1 |
| Bitterman, PB | 1 |
| Henke, CA | 1 |
| Pierre-Louis Odoom, J | 1 |
| Freeberg, MAT | 1 |
| Camus, SV | 1 |
| Toft, R | 1 |
| Szomju, BB | 1 |
| Sanchez Rosado, RM | 1 |
| Jackson, PD | 1 |
| Allegood, JC | 1 |
| Silvey, S | 1 |
| Liu, J | 1 |
| Cowart, LA | 1 |
| Weiss, E | 1 |
| Thatcher, TH | 1 |
| Sime, PJ | 2 |
| Nho, RS | 1 |
| Rice, C | 1 |
| Prasad, J | 1 |
| Bone, H | 1 |
| Farkas, L | 1 |
| Rojas, M | 1 |
| Horowitz, JC | 1 |
| Tang, J | 1 |
| Li, J | 1 |
| Li, G | 1 |
| Zhang, H | 1 |
| Wang, L | 1 |
| Li, D | 1 |
| Ding, J | 1 |
| Kottmann, R | 1 |
| Phipps, R | 1 |
| Sime, P | 1 |
| Worlitzsch, D | 1 |
| Meyer, KC | 1 |
| Döring, G | 1 |
| O'Dwyer, DN | 1 |
| Ashley, SL | 1 |
| Moore, BB | 1 |
| Kottmann, RM | 1 |
| Kulkarni, AA | 1 |
| Smolnycki, KA | 1 |
| Lyda, E | 1 |
| Dahanayake, T | 1 |
| Salibi, R | 1 |
| Honnons, S | 1 |
| Jones, C | 1 |
| Isern, NG | 1 |
| Hu, JZ | 1 |
| Nathan, SD | 1 |
| Grant, G | 1 |
| Phipps, RP | 1 |
| Tuder, RM | 1 |
| Lara, AR | 1 |
| Thannickal, VJ | 1 |
1 review available for lactic acid and Cryptogenic Fibrosing Alveolitis
| Article | Year |
|---|---|
Influences of innate immunity, autophagy, and fibroblast activation in the pathogenesis of lung fibrosis.
Topics: Animals; Autophagy; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Immunity, Innate; Intercellu | 2016 |
9 other studies available for lactic acid and Cryptogenic Fibrosing Alveolitis
| Article | Year |
|---|---|
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Topics: A549 Cells; Alveolar Epithelial Cells; Case-Control Studies; Energy Metabolism; Humans; Idiopathic P | 2021 |
Hypoxia enhances IPF mesenchymal progenitor cell fibrogenicity via the lactate/GPR81/HIF1α pathway.
Topics: Humans; Hypoxia; Idiopathic Pulmonary Fibrosis; Lactic Acid; Mesenchymal Stem Cells; Signal Transduc | 2023 |
Exhaled breath condensate identifies metabolic dysregulation in patients with radiation-induced lung injury.
Topics: Biomarkers; Breath Tests; Humans; Idiopathic Pulmonary Fibrosis; Lactic Acid; Lung; Lung Injury; Lun | 2023 |
Persistent hypoxia promotes myofibroblast differentiation via GPR-81 and differential regulation of LDH isoenzymes in normal and idiopathic pulmonary fibrosis fibroblasts.
Topics: Fibroblasts; Humans; Hypoxia; Idiopathic Pulmonary Fibrosis; Isoenzymes; L-Lactate Dehydrogenase; La | 2023 |
Spermidine-mediated poly(lactic-
Topics: Animals; Coumarins; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Idiopathic Pulmon | 2017 |
Reply: from idiopathic pulmonary fibrosis to cystic fibrosis: got lactate?
Topics: Cell Differentiation; Humans; Idiopathic Pulmonary Fibrosis; Lactic Acid; Myofibroblasts; Transformi | 2013 |
Lactate levels in airways of patients with cystic fibrosis and idiopathic pulmonary fibrosis.
Topics: Cell Differentiation; Humans; Idiopathic Pulmonary Fibrosis; Lactic Acid; Myofibroblasts; Transformi | 2013 |
Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β.
Topics: Case-Control Studies; Cell Differentiation; Gene Expression Regulation, Enzymologic; Humans; Hydroge | 2012 |
Lactate, a novel trigger of transforming growth factor-β activation in idiopathic pulmonary fibrosis.
Topics: Cell Differentiation; Humans; Idiopathic Pulmonary Fibrosis; Lactic Acid; Myofibroblasts; Transformi | 2012 |